SAKUMA Keiichiro 佐久間圭一朗

Researcher Number	90402891
Affiliation (Current)	2019: 愛知県がんセンター(研究所), がん病態生理学分野, ユニット長
Affiliation (based on the past Project Information) *help	2018 – 2019: 愛知県がんセンター(研究所), がん病態生理学分野, ユニット長 2016 – 2017: 愛知県がんセンター(研究所), 分子病態学部, 室長 2007 – 2016: 愛知県がんセンター(研究所), 分子病態学部, 主任研究員 2013: 愛知県がんセンター(研究所), 分子病態学部, 主任研究員
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Tumor biology Except Principal Investigator General medical chemistry / Tumor biology / Tumor biology / Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 喘息 / ホーミング / メモリーT細胞 / 糖鎖 / ヘルパーメモリーT細胞 / 硫酸基転移酵素 / 転写 / 上皮間葉転換 / 浸潤・転移 / 閉塞性肺疾患 … More Except Principal Investigator 転移 / 大腸がん / 生体分子医学 / 低酸素誘導因子 / マウスモデル / 転写調節 / シアル酸 / 細胞接着糖鎖 / 糖トランスポーター / ガングリオシド / リポーターアッセイ / クロマチン免疫沈降法 / シアル酸転移酵素 / 遺伝子導入 / 低酸素 / CD44 / ヒアルロン酸 / セレクチン / 生理活性脂質 / 糖脂質 / セラミド / LPA / シアリルルイスX / ケモカイン / シンデカン / CCR7 / CXCR4 / ヘパラン硫酸 / ジヒドロセラミド / DES1遺伝子 / 質量分析(ESI-MS / MS) / 長鎖脂肪酸(VLCFA) / 不飽和脂肪酸 / shRNA / shRNAライブラリー / スプライシング / RNA結合タンパク / トランスポゾン / 遺伝子改変マウス / 動物実験 / 上皮間葉転換 / マルチオミクス解析 / プロテオーム解析 Less

Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasisOngoing
- Principal Investigator
  
  青木正博
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Aichi Cancer Center Research Institute
Investigation of the roles of primary cilium in cancer metastasisPrincipal Investigator
- Principal Investigator
  
  佐久間圭一朗
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Elucidating the mechanisms of colorectal cancer metastasis using mouse models
- Principal Investigator
  
  Aoki Masahiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Development of new therapeutic strategy targeting epithelial-mesenchymal transition and sialyl lewis glycansPrincipal Investigator
- Principal Investigator
  
  Sakuma Keiichiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Aichi Cancer Center Research Institute
Development of in vivo screening systems for cancer metastasis suppressors
- Principal Investigator
  
  AOKI MASAHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  愛知県がんセンター(研究所)
Disordered expression of the homing receptor glycans on helper memory T cells in patients with severe bronchial asthmaPrincipal Investigator
- Principal Investigator
  
  SAKUMA Keiichiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Aichi Cancer Center Research Institute
Physiological significance of concerted action of cell adhesion molecules induced by hypoxia inducible factor
- Principal Investigator
  
  KANNAGI Reiji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Aichi Medical University
  Aichi Cancer Center Research Institute
Quantitation of carbohydrate homing-receptor molecules on helper memory T cells for evaluation of severity of bronchial asthma.Principal Investigator
- Principal Investigator
  
  SAKUMA Keiichiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Aichi Cancer Center Research Institute
Analysis of Transcription Clusters Induced by Hypoxia Inducible Factor (HIF)
- Principal Investigator
  
  KANNNAGI Reiji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Aichi Cancer Center Research Institute

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] INTESTINE2019
- Author(s)
  佐久間圭一朗、青木正博
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-16K07138
[Book] Gangliosides2018
- Author(s)
  Kannagi R, Cai BH, Huang HC, Chao CC, Sakuma K
- Publisher
  Springer
- ISBN
  9781493985524
- Data Source
  KAKENHI-PROJECT-16K07138
[Book] がん転移学2017
- Author(s)
  佐久間圭一朗、青木正博
- Total Pages
  654
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-16K07138
[Book] 蛋白質・核酸・酵素「セレクチンと相互作用する糖鎖の機能と発現調節」2008
- Author(s)
  神奈木玲児, 陳国云, 佐久間圭一朗, 大森勝之
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-20790583
[Journal Article] Clinical and in vitro studies of the correlation between MGMT and the effect of streptozocin in pancreatic NET2018
- Author(s)
  Hijioka Susumu、Sakuma Keiichiro、Aoki Masahiro、Mizuno Nobumasa、Kuwahara Takamichi、Okuno Nozomi、Hara Kazuo、Yatabe Yasushi
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: 83 Pages: 43-52
- DOI
  10.1007/s00280-018-3700-y
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-18H02686, KAKENHI-PROJECT-16K07138
[Journal Article] HNRNPLL stabilizes mRNA for DNA replication proteins and promotes cell cycle progression in colorectal cancer cells2018
- Author(s)
  Sakuma Keiichiro、Sasaki Eiichi、Kimura Kenya、Komori Koji、Shimizu Yasuhiro、Yatabe Yasushi、Aoki Masahiro
- Journal Title
  
  Cancer Sci
  
  Volume: 109 Pages: 2458-2468
- DOI
  10.1111/cas.13660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111005, KAKENHI-PROJECT-18H02686, KAKENHI-PROJECT-16K07138
[Journal Article] HNRNPLL, a newly identified colorectal cancer metastasis suppressor, modulates alternative splicing ofCD44during epithelial-mesenchymal transition2018
- Author(s)
  Sakuma K, Sasaki E, Kimura K, Komori K, Shimizu Y, Yatabe Y, Aoki M.
- Journal Title
  
  Gut
  
  Volume: 印刷中 Pages: 1103-1111
- DOI
  10.1136/gutjnl-2016-312927
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290045, KAKENHI-PROJECT-16K07138, KAKENHI-PLANNED-26111005
[Journal Article] Induction of 6-sulfated glycans with cell adhesion activity via T-bet and GATA-3 in human helper T cells.2012
- Author(s)
  Sakuma K, Chen GY, Aoki M, Kannagi R.
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: 1820 Pages: 841-848
- DOI
  10.1016/j.bbagen.2012.03.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790774, KAKENHI-PROJECT-23300349, KAKENHI-PROJECT-24590364, KAKENHI-PROJECT-24650627, KAKENHI-PUBLICLY-23112520
[Journal Article] Sialic acid cyclization of human Th homing receptor glycan associated with recurrent exacerbations of atopic dermatitis2012
- Author(s)
  Sakuma K, Aoki M, Kannagi R
- Journal Title
  
  J. Dermatol. Sci
  
  Volume: 68 Pages: 187-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650627
[Journal Article] Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors siglec-7 and -9.2012
- Author(s)
  Miyazaki, K., Sakuma, K., Kawamura, Y. I., Izawa, M., Ohmori, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Suzuki, A., Saito, Y., Dohi, T., and Kannagi, R.
- Journal Title
  
  Journal of Immunology
  
  Volume: 188 Pages: 4690-4700
- DOI
  10.4049/jimmunol.1100605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590324, KAKENHI-PROJECT-22590712, KAKENHI-PROJECT-22790774, KAKENHI-PUBLICLY-23112520, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-23770164
[Journal Article] Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition2012
- Author(s)
  Sakuma K, Aoki M, Kannagi R
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Pages: 7776-7781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650627
[Journal Article] Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial-mesenchymal transition2012
- Author(s)
  Sakuma K, Aoki M, Kannagi R.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A.
  
  Volume: 109(20) Pages: 7776-7781
- DOI
  10.1073/pnas.1111135109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790774, KAKENHI-PROJECT-23300349, KAKENHI-PROJECT-24590364, KAKENHI-PROJECT-24650627, KAKENHI-PUBLICLY-23112520
[Journal Article] Induction eof 6-sulfated glycans with cell adhesion activity via T-bet and GATA-3 in human helper T cells2012
- Author(s)
  Sakuma K, Chen GY, Aoki M, Kannagi R
- Journal Title
  
  Biochem. Biophys. Acta
  
  Volume: 1820 Pages: 841-848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24650627
[Journal Article] Sialylated and sulfated carbohydrate ligands for selecting and siglecs : involvement in traffic and homing of human memory T and B lymphocytes2011
- Author(s)
  Kannagi, R., Ohmori, K., Chen, G. Y., Miyazaki, K., Izawa, M., and Sakuma, K.
- Journal Title
  
  Adv.Exp.Med.Biol.
  
  Volume: 705 Pages: 549-569
- DOI
  10.1007/978-1-4419-7877-6_29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590324, KAKENHI-PROJECT-22790774, KAKENHI-PUBLICLY-23112520
[Journal Article] Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia : Clues in the ongoing search for new tumor markers2010
- Author(s)
  Kannagi, R., Sakuma, K., Miyazaki, K., Lim, K-T., Yusa, A., Yin, J., and Izawa, M.
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Pages: 586-593
- DOI
  10.1111/j.1349-7006.2009.01455.x
- NAID
  10026588975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590324
[Journal Article] Altered expression of glycan genes in cancers induced by epigenetic silencing and tumor hypoxia: Clues in the ongoing search for new tumormarkers.2010
- Author(s)
  Kannagi R, Sakuma K, et, al.
- Journal Title
  
  Cancer Science 101(3)
  
  Pages: 586-593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790583
[Journal Article] Significance of NF-κB/GATA Axis in Tumor Necrosis Factor-α-induced Expression of 6-Sulfated Cell Recognition Glycans in Human T-lymphocytes.2008
- Author(s)
  Guo-Yun Chen, Sakuma K, Kannagi R.
- Journal Title
  
  Journal of Biological Chemistry 283
  
  Pages: 34563-34570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790583
[Journal Article] Significance of NF-kB/GATA axis in TNF-α-induced expression of 6-sulfated cell-recognition glycans in human T-lymphocytes2008
- Author(s)
  Chen, G.-Y, Sakuma, K., Kannagi, R.
- Journal Title
  
  J. Biol. Chem. 283
  
  Pages: 34563-34570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590298
[Presentation] The roles of tumor microenvironment in cancer metastasis2018
- Author(s)
  青木正博、前田亮、小島康、佐久間圭一朗
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] Identification of HNRNPLL as a novel metastasis suppressor of colorectal cancer2018
- Author(s)
  Masahiro Aoki, Eiichi Sasaki, Kenya Kimura, Koji Komori, Yasuhiro Shimizu, Yasushi Yatabe, Keiichiro Sakuma
- Organizer
  AACR Annual Meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] HNRNPLL is a novel colon cancer metastasis suppressor that regulates alternative splicing of CD44 during epithelial-mesenchymal transition2018
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第10回NAGOYAグローバルリトリート
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] HNRNPLLはDNA複製制御因子のmRNAを安定化することで大腸がん細胞の細胞周期を促進する2018
- Author(s)
  佐久間圭一朗
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18H02686
[Presentation] HNRNPLL is a novel metastasis suppressor of colorectal2018
- Author(s)
  青木正博、佐久間圭一朗
- Organizer
  第70回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] HNRNPLL promotes cell cycle progression in colon cancer cells by stabilizing mRNAs for regulators of DNA replication2018
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] Phenotypic roles of HNRNPLL in epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions of colon cancer cells2017
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] HNRNPLLは大腸がん細胞のEMTとMETにおける形質変化に関与する2017
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Identification of HNRNPLL as a novel metastasis suppressor of colorectal cancer2016
- Author(s)
  青木正博、佐久間圭一朗
- Organizer
  第41回内藤コンファレンス
- Place of Presentation
  シャトレーゼ　ガトーキングダム　サッポロ（北海道・札幌市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 大腸がんの新規転移抑制因子HNRNPLLは上皮間葉転換におけるCD44の選択的スプライシングを制御する2016
- Author(s)
  青木正博、佐久間圭一朗
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] 新規大腸がん転移抑制因子HNRNPLLによってスプライシングを受ける遺伝子の同定2016
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Identification of the genes spliced by a novel colon cancer metastasis suppressor HNRNPLL2016
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Data Source
  KAKENHI-PROJECT-16K07138
[Presentation] An in vivo sh RNA screen identifies HNRNPLL as a novel colorctal cancer metastasis2016
- Author(s)
  Aoki M, Sakuma K
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer
- Place of Presentation
  Lahaina (USA)
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-25430129
[Presentation] An in vivo sh RNA screen identifies HNRNPLL as a novel colorctal cancer metastasis2016
- Author(s)
  Aoki, M. Sakuma, K.
- Organizer
  Tenth AACR-JCA Joint Conference on Breakthroughs in Cancer Research: From Biology to Therapeutics
- Place of Presentation
  Lahaina (USA)
- Year and Date
  2016-02-19
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] 大腸がん転移抑制因子候補HNRPLLは上皮間葉転換によって負の制御を受ける2015
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] A genome-wide shRNA library screen for colon cancer metastasis suppressor genes2015
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  第7回NAGOYAグローバルリトリート
- Place of Presentation
  あいち健康プラザ(大府市)
- Year and Date
  2015-02-13
- Data Source
  KAKENHI-PROJECT-25430129
[Presentation] 大腸がん転移抑制因子候補HNRPLLは上皮間葉転換によって負の制御を受ける2015
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場 (名古屋市)
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-25430129
[Presentation] shRNAライブラリーを用いた大腸がん転移抑制遺伝子のゲノムワイドスクリーニング2014
- Author(s)
  佐久間圭一朗、青木正博
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-25430129
[Presentation] shRNA ライブラリーを用いた大腸がん転移抑制遺伝子のゲノムワイドスクリーニング2014
- Author(s)
  佐久間　圭一朗、青木正博
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26290045
[Presentation] Sialyl Lewis glycan expression is linked with epithelial-mesenchymal transition in colon cancer cells2013
- Author(s)
  Sakuma K, Kannagi R, and Aoki M
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋(ウインクあいち)
- Data Source
  KAKENHI-PROJECT-25430129
[Presentation] 大腸がん細胞においてシアリルルイス糖鎖の発現とEMTは関連する2013
- Author(s)
  佐久間圭一朗、神奈木玲児、青木正博
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24650627
[Presentation] c-MycとCDX2はEMTを起こした大腸がん細胞におけるE-セレクチンリガンド糖鎖の発現を媒介する2012
- Author(s)
  佐久間圭一朗、神奈木玲児、青木正博
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24650627
[Presentation] Th2-specific homing ligands involved in recurrent atopic dermatitis exacerbations2011
- Author(s)
  佐久間圭一朗
- Organizer
  日本免疫学会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790774
[Presentation] Th2-specific homing ligands involved in recurrent atopic dermatitis exacerbations.2011
- Author(s)
  佐久間圭一朗、古橋卓也、近藤幸子、矢部宇一郎、大森勝之、森田明理、神奈木玲児
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-22790774
[Presentation] EGF and bFGF induce EMT and E-selectin ligandglycan expression on colorectal cancer cells2011
- Author(s)
  佐久間圭一朗、青木正博、神奈木玲児
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22790774
[Presentation] Carbohydrate-mediated cell adhesion involved in pathogenic homing behaviors of T-and B-lymphocytes2009
- Author(s)
  Kannagi R, Sakuma K, Miyazaki K, Kimura N, Ohmori K
- Organizer
  20th International Symposium on Glycoconjugates
- Place of Presentation
  Puerto Rico
- Year and Date
  2009-12-29
- Data Source
  KAKENHI-PROJECT-21590324
[Presentation] Th2疾患における6-硫酸化糖鎖の異常発現に対するGATA-3関与の可能性2009
- Author(s)
  佐久間圭一朗
- Organizer
  日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790583
[Presentation] ヘルパーT細胞における6-硫酸基転移酵素遺伝子の発現調節機構2008
- Author(s)
  佐久間圭一朗
- Organizer
  日本免疫学会学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20790583
[Presentation] Regulation of glycosyltransferase gene expression involved in lymphocyte homing2008
- Author(s)
  Chen G-Y, Sakuma K, Kannagi R
- Organizer
  Sixth International Glycosyltransferase Conference (GlycoT2008)
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-19590298
[Presentation] Sialylated and sulfated ligands on human B-lymphocytes for CD22/Siglec22008
- Author(s)
  Kannagi R, Ohmori K, Sakuma K, Kimura N
- Organizer
  The 12th International Conference on Biology and Chemistry of Sialic Acid (SialoGlycoT2008)
- Place of Presentation
  St.Petersburg, Russia
- Data Source
  KAKENHI-PROJECT-19590298
[Presentation] 大腸がん細胞においてシアリルルイス糖鎖の発現とEMTは関連する
- Author(s)
  佐久間圭一朗、神奈木玲児、青木正博
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウインク愛知（名古屋市中村区）
- Data Source
  KAKENHI-PROJECT-24650627
[Presentation] c-MycとCDX2はEMTを起こした大腸がん細胞におけるE-セレクチンリガンド糖鎖の発現を媒介する
- Author(s)
  佐久間圭一朗
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  さっぽろ芸文館 (札幌)
- Data Source
  KAKENHI-PROJECT-24650627

1. AOKI MASAHIRO (60362464)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
2. KOJIMA Yasushi (30464217)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. KANNNAGI Reiji (80161389)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. GOTO Yoshiko (30416169)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAGUCHI Osamu (00142167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KYOGASHIMA Mamoru (50225091)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. YASUKAWA Zennta (60443454)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 梶野リエ (20633184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 藤下晃章 (50511870)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TAKEDA Junji (50163407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 三城恵美 (00455544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMAJI Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 河村由紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 土肥多恵子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKUMA Keiichiro 佐久間 圭一朗

Research Projects

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Molecular mechanisms and preventive/therapeutic targets of colon cancer metastasisOngoing

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Investigation of the roles of primary cilium in cancer metastasisPrincipal Investigator

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Elucidating the mechanisms of colorectal cancer metastasis using mouse models

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Development of new therapeutic strategy targeting epithelial-mesenchymal transition and sialyl lewis glycansPrincipal Investigator

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Development of in vivo screening systems for cancer metastasis suppressors

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Disordered expression of the homing receptor glycans on helper memory T cells in patients with severe bronchial asthmaPrincipal Investigator

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Physiological significance of concerted action of cell adhesion molecules induced by hypoxia inducible factor

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Quantitation of carbohydrate homing-receptor molecules on helper memory T cells for evaluation of severity of bronchial asthma.Principal Investigator

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Analysis of Transcription Clusters Induced by Hypoxia Inducible Factor (HIF)

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[Book] INTESTINE2019

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[Book] Gangliosides2018

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[Book] がん転移学2017

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[Book] 蛋白質・核酸・酵素「セレクチンと相互作用する糖鎖の機能と発現調節」2008

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[Journal Article] Clinical and in vitro studies of the correlation between MGMT and the effect of streptozocin in pancreatic NET2018

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SAKUMA Keiichiro 佐久間圭一朗