Sato Takeshi 佐藤毅

… Alternative Names

佐藤毅サトウタケシ

SATO Takeshi 佐藤毅

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Researcher Number	90403013
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 京都薬科大学, 薬学部, 教授 2018: 京都薬科大学, 一般教育分野, 教授 2014 – 2017: 大阪大学, たんぱく質研究所, 講師 2013: 大阪大学, たんぱく質研究所, 助教 2012: 大阪大学, 蛋白質研究所, 助教 … More 2007 – 2008: 大阪大学, 蛋白質研究所, 助教 2007: Osaka University, たんぱく質研究所, 助教 2006: 大阪大学, 蛋白質研究所, 助手 Less
Review Section/Research Field	Principal Investigator Structural biochemistry / Basic Section 43020:Structural biochemistry-related / Living organism molecular science Except Principal Investigator Bio-related chemistry / Structural biochemistry / Biological Sciences
Keywords	Principal Investigator 膜タンパク質 / 固体NMR / 生体膜 / 半合成 / ライゲーション / 受容体型チロシンキナーゼ / 情報伝達 / Ligation / Notch受容体 / 分子動力学計算 … More / Notch / context dependency / マイクロドメイン / Context dependency / Notchシグナリング / 膜タンパク質の再構成 / リポソーム / 生物物理 / 再構成 / 線維芽細胞増殖因子受容体 / 膜近傍部位 / 膜貫通部位 / 構造生物学 / 膜貫通―膜近傍部位 / 膜蛋白質 / 活性発現の分子機構 … More Except Principal Investigator 膜タンパク質 / ペプチドチオエステル / ライゲーション法 / 化学合成 / 膜蛋白質 / セグメント縮合 / チオエステル法 / 翻訳後修飾 / 固相合成法 / 特異的修飾 / カベオリン / 蛋白質 / 立体構造解析 / 酵素 / シグナル伝達 / タンパク質 / Argタグ補助基 / 選択的縮合法 / 4回膜貫通型受容体 / 光反応性補助基 / Fmoc法 / v-ATPase / EGF 受容体 / 電位依存性プロトンチャネル / EGF受容体 / 膜近傍部位 / 合成法 / 溶解性 / 補助基 Less

Mechanism of Notch receptor signaling and its dependency on lipidsPrincipal Investigator
- Principal Investigator
  
  Sato Takeshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  Kyoto Pharmaceutical University
Chemical synthesis of caveolin
- Principal Investigator
  
  Hojo Hironobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bio-related chemistry
- Research Institution
  Osaka University
Elucidation of substrate recognition mechanism of I-CLiP in the trans- and juxta-membrane regions
- Principal Investigator
  
  NOGI Terukazu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University
Developing strategy for uni-directional insertion of single transmembrane protein to liposomePrincipal Investigator
- Principal Investigator
  
  Sato Takeshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Semi-synthesis of receptor tyrosine kinase and its structure and function analysisPrincipal Investigator
- Principal Investigator
  
  Sato Takeshi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Osaka University
Function of the transmembrane-juxtamembrane region of receptor tyrosine kinase in its activity regulationPrincipal Investigator
- Principal Investigator
  
  SATO Takeshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
Development of a method for membrane protein synthesis based on ligation chemistry
- Principal Investigator
  
  AIMOTO Saburo
- Project Period (FY)
  2003 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University

[Journal Article] Characterizing interaction between the juxtamembrane region of the single transmembrane protein and membrane using chemically synthesized peptides2023
- Author(s)
  Sato Takeshi、Shinohara Akira
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 3 Pages: 102454-102454
- DOI
  10.1016/j.xpro.2023.102454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06038
[Journal Article] Threonine phosphorylation regulates the molecular assembly and signaling of EGFR in cooperation with membrane lipids.2022
- Author(s)
  2)Ryo Maeda, Hiroko Tamagaki-Asahina, Takeshi Sato, Masataka Yanagawa, Yasushi Sako.
- Journal Title
  
  J Cell Sci.
  
  Volume: 135 Issue: 15 Pages: 1-12
- DOI
  10.1242/jcs.260355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06038, KAKENHI-PROJECT-19H05647, KAKENHI-PROJECT-20K05760
[Journal Article] Effect of hydrophobic moment on membrane interaction and cell penetration of apolipoprotein E-derived arginine-rich amphipathic α-helical peptides.2022
- Author(s)
  1)Yuki Takechi-Haraya, Takashi Ohgita, Mana Kotani, Hiroki Kono, Chihiro Saito, Hiroko Tamagaki-Asahina, Kazuchika Nishitsuji, Kenji Uchimura, Takeshi Sato, Ryuji Kawano, Kumiko Sakai-Kato, Ken-ichi Izutsu, Hiroyuki Saito
- Journal Title
  
  Sci. Rep.
  
  Volume: 12 Pages: 4959-4959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06038
[Journal Article] Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis2021
- Author(s)
  Prasada Rao Hanumanthu BD、Sato Takeshi、Challa Kiran、Fujita Yurika、Shinohara Miki、Shinohara Akira
- Journal Title
  
  eLife
  
  Volume: 10 Pages: 1-29
- DOI
  10.7554/elife.63119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22402, KAKENHI-PROJECT-19H00981, KAKENHI-PROJECT-21K06038
[Journal Article] Total Synthesis and Structural Characterization of Caveolin-12021
- Author(s)
  Hironobu Hojo, Toshiki Takei, Yuya Asahina, Nobuaki Okumura, Toshifumi Takao, Masatomo So, Isao Suetake, Takeshi Sato, Akihiro Kawamoto, Yoshio Hirabayashi
- Journal Title
  
  Angew Chem Int Ed Engl .
  
  Volume: 60 Issue: 25 Pages: 13900-13905
- DOI
  10.1002/anie.202100826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06038
[Journal Article] Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue2017
- Author(s)
  Kenta Arai+, Toshiki Takei+, Masaki Okumura+, Satoshi Watanabe+, Yuta Amagai, Yuya Asahina, Luis Moroder, Hironobu Hojo, Kenji Inaba, and Michio Iwaoka
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 印刷中 Issue: 20 Pages: 5522-5526
- DOI
  10.1002/anie.201701654
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-17K05792, KAKENHI-PROJECT-17K15098, KAKENHI-PROJECT-17K18123, KAKENHI-PUBLICLY-17H05868, KAKENHI-PROJECT-15H04335, KAKENHI-PLANNED-26116005
[Journal Article] Total Synthesis and Antibacterial Investigation of Plusbacin A32017
- Author(s)
  Katsuyama Akira、Paudel Atmika、Panthee Suresh、Hamamoto Hiroshi、Kawakami Toru、Hojo Hironobu、Yakushiji Fumika、Ichikawa Satoshi
- Journal Title
  
  Organic Letters
  
  Volume: 19 Issue: 14 Pages: 3771-3774
- DOI
  10.1021/acs.orglett.7b01629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H04180, KAKENHI-PROJECT-16H05097, KAKENHI-PROJECT-17J04794
[Journal Article] Development of SAAP3D force field and the application to replica-exchange Monte Carlo simulation for chignolin and C-peptide2017
- Author(s)
  Iwaoka Michio、Suzuki Toshiki、Shoji Yuya、Dedachi Kenichi、Shimosato Taku、Minezaki Toshiya、Hojo Hironobu、Onuki Hiroyuki、Hirota Hiroshi
- Journal Title
  
  . Comput. Aided Mol. Design
  
  Volume: 31 Issue: 12 Pages: 1039-1052
- DOI
  10.1007/s10822-017-0084-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K05792, KAKENHI-PROJECT-16H04180
[Journal Article] Synthetic transmembrane-juxtamembrane peptide for the structure and function of ErbB receptor tyrosine kinase2016
- Author(s)
  Takeshi Sato
- Journal Title
  
  Biopolymers Peptide Science
  
  Volume: 未定 Issue: 4 Pages: 613-621
- DOI
  10.1002/bip.22775
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26650015, KAKENHI-PROJECT-24687013
[Journal Article] Cooperative roles of hydrophilic loop 1 and the C terminus of presenilin 1 in the substrate-gating mechanism of γ-secretase.2015
- Author(s)
  Shizuka Takagi-Niidome, Tomoki Sasaki, Satoko Osawa, Takeshi Sato, Kanan Morishima, Tetsuo Cai, Takeshi Iwatsubo, and Taisuke Tomita
- Journal Title
  
  J. Neurosci.
  
  Volume: 35 Issue: 6 Pages: 2646-2656
- DOI
  10.1523/jneurosci.3164-14.2015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013, KAKENHI-PROJECT-26650015, KAKENHI-PROJECT-15H02492
[Journal Article] His499 Regulates Dimerization and Prevents Oncogenic Activation by Asparagine Mutations of the Human Thrombopoietin Receptor2015
- Author(s)
  Emilie Leroy, Jean-Philippe Defour, Takeshi Sato, Sharmila Dass, Vitalina Gryshkova, Shwe Myat Marlar, Judith Staerk, Stefan N. Constantinescu and Steven O. Smith
- Journal Title
  
  J.Biol.Chem
  
  Volume: 291 Issue: 6 Pages: 2974-2987
- DOI
  10.1074/jbc.m115.696534
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26650015, KAKENHI-PROJECT-24687013
[Journal Article] ペプチド化学を基礎とした受容体型チロシンキナーゼ膜貫通－膜近傍部位の構造解析2014
- Author(s)
  佐藤　毅
- Journal Title
  
  化学工業
  
  Volume: 65 Pages: 15-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26650015
[Journal Article] Coupling of transmembrane helix orientation to membrane release of the juxtamembrane region in FGFR32014
- Author(s)
  Hiroko Tamagaki, Yusuke Furukawa, Ritsuko Yamaguchi, Hironobu Hojo, Saburo Aimoto, Steven O. Smith and Takeshi Sato
- Journal Title
  
  Biochemistry
  
  Volume: 53 Issue: 30 Pages: 5000-5007
- DOI
  10.1021/bi500327q
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013, KAKENHI-PUBLICLY-25108513, KAKENHI-PROJECT-26650015
[Journal Article] A Cyclic KLVFF-Derived Peptide Aggregation Inhibitor Induces the Formation of Less Toxic Off-Pathway Amyloid Oligomers2014
- Author(s)
  Tadamasa Arai, Daisuke Sasaki, Takushi Araya, Takeshi Sato, Youhei Sohma and Motomu Kanai
- Journal Title
  
  ChemBioChem
  
  Volume: 17 Issue: 17 Pages: 2577-2583
- DOI
  10.1002/cbic.201402430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] Rational Design and Identification of Non-Peptidic Aggregation Inhibitor of Amyloid- Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-].2014
- Author(s)
  Tadamasa Arai, Takushi Araya, Daisuke Sasaki, Atsuhiko Taniguchi, Takeshi Sato, Youhei Sohma, and Motomu Kanai
- Journal Title
  
  Angew. Chem. Int. Ed
  
  Volume: 53 Issue: 31 Pages: 8236-8239
- DOI
  10.1002/anie.201405109
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] Structural Characterization of the Transmembrane-Intracellular Juxtamembrane Region of FGFR3 and Its Implication in the Activation Mechanism2014
- Author(s)
  Hiroko Tamagaki, Ritsuko Yamaguchi and Takeshi Sato
- Journal Title
  
  Peptide Science 2013
  
  Volume: 2013 Pages: 59-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] In vitro reconstitution of a cellular like environment using liposome for Aβ peptide aggregation, its propagation, peptide-lipid interaction and drug screening2014
- Author(s)
  Abhijit Saha,Goutam Mondal, Takeshi Sato and Surajit Ghosh
- Journal Title
  
  Peptide Science 2013
  
  Volume: 2013 Pages: 109-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] Interaction of the intracellular juxtamembrane region with lipid bilayersdepends on relative orientation of transmembrane regions 1n dimer forreceptor tyrosine kinase2013
- Author(s)
  Chihiro Matsushita, Hiroko Tamagaki, Saburo Aimoto, Steven O. Smith and Takeshi Sato
- Journal Title
  
  Peptide Science 2012
  
  Pages: 327-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] Structure of the transmembrane and the intacelllular juxtamembrane of FGFR3 in lipid bilayers2013
- Author(s)
  Hiroko Tamagaki, Saburo Aimoto and Takeshi Sato
- Journal Title
  
  Peptide Science 2012
  
  Pages: 325-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] Transmembrane helix orientation influences membrane binding of the intracellular juxtamembrane domain in Neu receptor peptides2013
- Author(s)
  Chihiro Matsushita, Hiroko Tamagaki, Yudai Miyazawa, Saburo Aimoto, Steven O. Smith and Takeshi Sato
- Journal Title
  
  Proc. Natl. Acad. Sci.USA,
  
  Volume: 110 Pages: 1646-1651
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] A Tryptophan at the Transmembrane-Cytosolic Junction Modulates Thrombopoietin Receptor Dimerization and Activation2013
- Author(s)
  Jean-Philippe Defour, Miki Itaya, Vitalina Gryshkova, Ian C. Brett, Christian Pecquet, Takeshi Sato, Steven O. Smith and Stefan N. Constantinescu
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 110 Issue: 7 Pages: 2540-2545
- DOI
  10.1073/pnas.1211560110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24687013
[Journal Article] Structure of the transmembrane dimer of the amyloid precursor protein: Implications for proteolysis by g-secretase2009
- Author(s)
  T. Sato, T.-C.Tang, G. Reubins, J.Z. Fei, T. Fujimoto, P. Kienlen-Campard, S. N. Constantinescu, J.-N. Octave, S. Aimoto, S. O. Smith
- Journal Title
  
  Proc. Natl Acad. Sci. USA 106
  
  Pages: 1421-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] AHelix-to-Coil Transition at the ε -Cut Site in the Transmembrane Dimer of the Amyloid Precursor Protein is Required for Proteolysis2009
- Author(s)
  Takeshi Sato, Tzu-chun Tang, Gabriella Reubins, Jeffrey Z. Fei, Taiki Fujimoto, Pascal Kienlen-Campard, Stefan N. Constantinescu, Jean-Noel Octave, Saburo Aimoto, Steven O. Smith.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 106
  
  Pages: 1421-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] Structure of the Transmembrane2009
- Author(s)
  Takeshi Sato, Tzu-chun Tang, Gabriella Reubins, Jeffrey Z. Fei, Taiki Fujimoto, Hiroko Tamagaki, Pascal Kienlen-Campard, Stefan N. Constantinescu, Jean-Noel Octave, Steven O. Smith and Saburo Aimoto
- Journal Title
  
  Juxtamembrane Region of Amyloid Peptide Science 2008
  
  Pages: 89-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] A Helix-to-Coil Transition at the ε-Cut Site in the Transmembrane Dimer of the Amyloid Precursor Protein is Required for Proteolysis2009
- Author(s)
  Sato, Takeshi
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 106
  
  Pages: 1421-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] A Helix-to-Coil Transition at the ε-Cut Site in the Transmembrane Dimer of the Amyloid Precursor Protein is Reauired for Proteolvsis2009
- Author(s)
  T. Sato
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 106
  
  Pages: 1421-1426
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide purification by affinity chromatography based on α-ketoacyl group chemistry2009
- Author(s)
  T. Hara, A. Tainosho, K. Nakamura, T. Sato, T. Kawakami, S. Aimoto
- Journal Title
  
  J. Peptide Sci. 15
  
  Pages: 369-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Chemical Synthesis of the Extracellular Juxtamembrane-Transmembrane Region of Thrombopoietin Receptor2008
- Author(s)
  Tomoya Uesugi, Ken'ichiroh Nakamura, Takeshi Sato, Toru Kawakami and Saburo Aimoto
- Journal Title
  
  Peptide Science 2007
  
  Pages: 211-212
- NAID
  10021906895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] Peptide Thioester Synthesis Based on an N-S Acyl Shift Reaction2008
- Author(s)
  Ken'ichiroh Nakamura, Tomoya Uesugi, Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  Peptide Science 2007
  
  Pages: 41-42
- NAID
  10021906551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] Structural Analysis of the Transmembrane-Juxtamembrane Region of FGFR32008
- Author(s)
  Yusuke Furukawa, Takeshi Sato, Chihiro Matsushita, Yuen H. Lam, Xin Zhao, Steven O. Smith and Saburo Aimoto
- Journal Title
  
  Peptide Science 2007
  
  Pages: 319-320
- NAID
  10021907085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] Jean-Noel Octave Amyloidogenic processing but not aicd production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs2008
- Author(s)
  Pascal Kienlen-Campard, Bernadette Tasiaux, Joanne Van Hees, Mingli Li, Sandra Huysseune, Takeshi Sato, Jeffrey. Z. Fei, Saburo Aimoto, Pierre J. Courtoy, Steven O. Smith, Stefan N.Constantinescu, Jean-Noel
- Journal Title
  
  J. Biol Chem. 283
  
  Pages: 7733-7744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] Structure of the Membrane Reconstituted Transmembrane-Juxtamembrane Peptide Neu(647-693) and Its Interaction with Ca2+/Calmodulin2008
- Author(s)
  Chihiro Matsushita, Takeshi Sato, Yusuke Furukawa, Yuen Han Lam, Xin Zhao, Steven O. Smith, Saburo Aimoto
- Journal Title
  
  Peptide Science 2007
  
  Pages: 501-502
- NAID
  10021907427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] Inhibitors of amyloid toxicity based on beta-sheet packing of Aβ40 and Aβ42.2006
- Author(s)
  T. Sato, P. Kienlen-Campard, M. Ahmed, W. Liu, H. Li, J. I. Elliott, S. Aimoto, S. N. Constantinescu, J. N. Octave, S. O. Smith
- Journal Title
  
  Biochemistry 45
  
  Pages: 5503-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Inhibitors of arnyloid toxicity based on beta-sheet packing of Abeta40 and Abeta422006
- Author(s)
  T.Sato
- Journal Title
  
  Biochemistry 45
  
  Pages: 5503-5516
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Synthesis of the C-terminal Region of Opioid Receptor Like 1 in an SDS Micelle by the Native Chemical Ligation: Effect of Thiol Additive and SDS Concentration on Ligation Efficiency,2005
- Author(s)
  T. Sato, Y. Saito, S. Aimoto
- Journal Title
  
  J. Peptide Sci. 11
  
  Pages: 410-416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Synthesis of the C-terminal Region of Opioid Receptor Like 1 in an SDS Micelle by the Native CChemical Ligation Effect of Thiol Additive and SDS Concentration on Ligation Efficiency2005
- Author(s)
  T.Sato
- Journal Title
  
  J.Peptide Sci. 11
  
  Pages: 410-416
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Synthesis of the C-terminal Region of Opioid Receptor Like 1 in an SDS Micelle by the Native Chemical Ligation : Effect of Thiol Additive and SDS Concentration on Ligation Efficiency.2004
- Author(s)
  T.Sato
- Journal Title
  
  J.Peptide Sci., Epub. Dec.
  
  Pages: 20-20
- Data Source
  KAKENHI-PROJECT-15083204
[Journal Article] Peptide purification by affinity chromatography based on α-ketoacyl group chemistry
- Author(s)
  Toshiaki Hara, Akira Tainosho, Ken'ichiroh Nakamura, Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Journal Title
  
  J. Pept. Sci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Journal Article] High resolution 1H MAS RFDR NMR of biological membranes
- Author(s)
  Darryl Aucoin, Devin Camenares, Xin Zhao, Jay Jung, Takeshi Sato and Steven O. Smith
- Journal Title
  
  J. Mag.Reson. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] What's going on in the membrane, activation mechanism of receptor tyrosine kinase2023
- Author(s)
  Takeshi Sato
- Organizer
  International Symposium at National Taiwan University, School of Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06038
[Presentation] 受容体型チロシンキナーゼの膜貫通―膜近傍部位の構造機能解析2016
- Author(s)
  佐藤　毅
- Organizer
  蛋白研セミナー
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府吹田市）
- Year and Date
  2016-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 受容体型チロシンキナーゼの膜貫通―膜近傍部位の構造機能解析2016
- Author(s)
  佐藤　毅
- Organizer
  蛋白研セミナー
- Place of Presentation
  ホテル阪急エキスポパーク(大阪府吹田市）
- Year and Date
  2016-03-03
- Invited
- Data Source
  KAKENHI-PROJECT-26650015
[Presentation] 合成ペプチドを用いた１回膜貫通型タンパク質の構造機能解析2015
- Author(s)
  佐藤　毅
- Organizer
  第15回日本蛋白質科学会年会ワークショップ「生体膜上における事象の分子機構解明を目指すペプチド生命科学」
- Place of Presentation
  徳島あわぎんホール(徳島県徳島市）
- Year and Date
  2015-06-24
- Invited
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] Research on structure and function of membrane protein using synthetic transmembrane peptides2015
- Author(s)
  Takeshi Sato
- Organizer
  19th Korean Peptide Protein Symposium
- Place of Presentation
  Choongchungnam(韓国）
- Year and Date
  2015-07-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26650015
[Presentation] Research on structure and function of membrane protein using synthetic transmembrane peptides2015
- Author(s)
  Takeshi Sato
- Organizer
  19th Korean Peptide Protein Symposium
- Place of Presentation
  Choongchungnam(韓国）
- Year and Date
  2015-07-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 合成ペプチドを用いた１回膜貫通型タンパク質の構造機能解析2015
- Author(s)
  佐藤　毅
- Organizer
  第15回日本蛋白質科学会年会ワークショップ「生体膜上における事象の分子機構解明を目指すペプチド生命科学」
- Place of Presentation
  徳島あわぎんホール(徳島県徳島市）
- Year and Date
  2015-06-24
- Invited
- Data Source
  KAKENHI-PROJECT-26650015
[Presentation] EGFR膜貫通－膜近傍部位の構造機能解析2014
- Author(s)
  佐藤　毅
- Organizer
  第87回日本生化学会, 京都2014.　フォーラム「次世代脂質生物学を支える革新的テクノロジー」
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] EGFR膜貫通－膜近傍部位の構造機能解析2014
- Author(s)
  佐藤　毅
- Organizer
  第87回日本生化学会, 京都2014.　フォーラム「次世代脂質生物学を支える革新的テクノロジー」
- Place of Presentation
  京都国際会館
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26650015
[Presentation] ペプチド化学を基盤とした受容体チロシンキナーゼ膜貫通-膜近傍部位の構造機能解析2014
- Author(s)
  佐藤　毅
- Organizer
  生命分子機能研究会セミナー2014
- Place of Presentation
  滋賀県長浜市
- Invited
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 繊維芽細胞増殖因子受容体3の膜貫通-膜近傍部位の機能構造解析2013
- Author(s)
  玉垣裕子, 相本三郎, 佐藤　毅
- Organizer
  第86回日本生化学会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] Structural change in the transmembrane-juxtamembrane region of receptor tyrosine kinase for its activation2013
- Author(s)
  Takeshi Sato
- Organizer
  Membrane Protein Folding organized by the Biophysical Society (US) and the Korean Institute for Advanced Study
- Place of Presentation
  Seoul, South Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] Structural Characterization of the Transmembrane-Intracellular Juxtamembrane Region of FGFR3 and Its Implication in the Activation Mechanism2013
- Author(s)
  Hiroko Tamagaki, Ritsuko Yamaguchi and Takeshi Sato
- Organizer
  第５０回日本ペプチド討論会・第４回アジア太平洋国際ペプチド学会
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] In vitro reconstitution of a cellular like environment using liposome for Aβ peptide aggregation, its propagation, peptide-lipid interaction and drug screening2013
- Author(s)
  Abhijit Saha,Goutam Mondal, Takeshi Sato and Surajit Ghosh
- Organizer
  第５０回日本ペプチド討論会・第４回アジア太平洋国際ペプチド学会
- Place of Presentation
  大阪府吹田市
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] EGF受容体ファミリーの活性化機構における膜貫通-細胞質内膜近傍部位の機能の解析2013
- Author(s)
  松下千紘, 玉垣裕子, 相本三郎, Steven O. Smith, 佐藤　毅
- Organizer
  第86回日本生化学会
- Place of Presentation
  神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] Structural biology on membrane protein using synthetic transmembrane peptides2013
- Author(s)
  佐藤毅
- Organizer
  4th Indian Peptide Symposium
- Place of Presentation
  Saha Institute of Nuclear Physics (インド・コルカ(招待講演)
- Year and Date
  2013-02-22
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 一回膜貫通型蛋白質の半合成化学的調製2012
- Author(s)
  玉垣裕子, 相本三郎, 佐藤毅
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 繊維芽細胞増殖因子受容体(FGFR3)膜貫通一細胞質内膜近傍部位の脂質二重膜中における構造解析2012
- Author(s)
  玉垣裕子, 相本三郎, 佐藤毅
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島県民交流センター(鹿児島市)
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 1回膜貫通型受容体活性化における膜貫通・膜近傍部位の機能解析2012
- Author(s)
  佐藤毅, 玉垣裕子, 杣本三郎, Steven O. Smith
- Organizer
  第12回日本蛋白質科学会年会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2012-06-21
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] Structure of the transmembrane-juxtamembrane region of the amyloid precursor protein : Implication for proteolvsis at the ε-cut site2009
- Author(s)
  Sato, Takeshi
- Organizer
  Life Science against Intractable Diseases, The joint Symposium of the 4th International Symposium of Institutes Network and Osaka University Global COE Symposium
- Place of Presentation
  Hotel Hankyu Expo Park吹田
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the transmembrane-juxtamembrane region of the amyloid precursor protein : Implication for proteolysis at the ε-cut site2009
- Author(s)
  Takeshi Sato, Steven O. Smith, Saburo Aimoto
- Organizer
  Life Science against Intractable Diseases, The joint Symposium of the 4th International Symposium of Institutes Network and Osaka University Global COE Symposium
- Place of Presentation
  Hotel Hankyu Expo Park
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] FGFR3膜貫通-細胞質内膜近傍部位の構造解析2008
- Author(s)
  佐藤毅, 古川祐輔, 松下千紘, Steven O. Smith, 相本三郎
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the transmembrane-juxtamembrane region of single transmembrane proteins2008
- Author(s)
  Sato, Takeshi
- Organizer
  The 7th OIB Symposium
- Place of Presentation
  岡崎カンファレンスセンター、岡崎
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the Transmembrane - Juxtamembrane Region of Amyloid Precursor Protein2008
- Author(s)
  Takeshi Sato, Tzu-chun Tang, Gabriella Reubins, Jeffrey Z. Fei, Taiki Fujimoto, Hiroko Tamagaki, Pascal Kienlen-Campard, Stefan N. Constantinescu, Jean-Noel Octave, Steven O. Smith and Saburo Aimoto
- Organizer
  第45 回日本ぺプチド討論会
- Place of Presentation
  2008 タワーホール船堀
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structural studies on the membrane reconstituted transmembrane-juxtamembrane region of ErbB2/Neu2008
- Author(s)
  Chihiro Matsushita, Takeshi Sato, Yusuke Furukawa, Yuen Han Lam, Xin Zhao, Steven O. Smith and Saburo Aimoto
- Organizer
  30th European Peptide Symposium
- Place of Presentation
  Finlandia Hall, Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the transmembrane-juxtamembrane region of single transmembrane proteins2008
- Author(s)
  Takeshi Sato, Steven O. Smith, Saburo Aimoto
- Organizer
  The 7th OIB Symposium
- Place of Presentation
  岡崎カンファレンスセンター, 岡崎
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] ネイティブケミカルラィゲーショシ法によるFGFR3膜貫通一膜近傍部位ベプチドの化学合成2007
- Author(s)
  佐藤毅
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] ネイティブケミカルライゲーション法によるFGFR3膜貫通-膜近傍部位ぺプチドの化学合成2007
- Author(s)
  古川祐輔, 佐藤毅, Steven O. Smith, 相本三郎
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Chemical Synthesis of the Extracellular Juxtamembrane-Transmembrane Region of Thrombopoietin Receptor2007
- Author(s)
  Tomoya Uesugi, Ken'ichiroh Nakamura, Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Organizer
  第44回日本ぺプチド討論会2007
- Place of Presentation
  富山国際会議場富山
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structural Analysis of the Transmembrane-Juxtamembrane Region of FGFR32007
- Author(s)
  Yusuke Furukawa, Takeshi Sato, Chihiro Matsushita, Yuen H. Lam, Xin Zhao, Steven O. Smith, Saburo Aimoto
- Organizer
  第44回日本ぺプチド討論会2007
- Place of Presentation
  富山国際会議場富山
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the transmembrane and juxtamembrane region of Neu and FGFR32007
- Author(s)
  Takeshi Sato, Yusuke Furukawa, Chihiro Matsushita, Steven O. Smith, Saburo Aimoto
- Organizer
  第30回日本分子生物学会/第80回日本生化学会合同大会
- Place of Presentation
  パシフィコ横浜、ヨコハマグランドイインターコンチネンタルホテル横浜
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the Membrane Reconstituted Transmembrane-Juxtamembrane Peptide Neu(647-693) and Its Interaction with Ca2+/Calmodulin2007
- Author(s)
  Chihiro Matsushita, Takeshi Sato, Yusuke Furukawa, Yuen Han Lam, Xin Zhao, Steven O. Smith and Saburo Aimoto
- Organizer
  第44回日本ぺプチド討論会2007
- Place of Presentation
  富山国際会議場富山
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Peptide Thioester Synthesis Based on an N-S Acyl Shift Reaction2007
- Author(s)
  Ken'ichiroh Nakamura, Tomoya Uesugi,Takeshi Sato, Toru Kawakami, Saburo Aimoto
- Organizer
  第44回日本ぺプチド討論会2007
- Place of Presentation
  富山国際会議場富山
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structural Analysis of the Transmembrane-Juxtarnembrane Regien of FGFR32007
- Author(s)
  Takeshi Sato
- Organizer
  第44回日本ペプチド討論会
- Place of Presentation
  富山
- Year and Date
  2007-11-07
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the transmembrane and juxtamembran e region of Neu and FGFR32007
- Author(s)
  Takeshi Sato
- Organizer
  第30回日本分子生物学会/第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Chemical Synthesis of the Extracellular Juxtamembrane-Transmembrane Region of Thrombopoietin Receptor2007
- Author(s)
  Takeshi Sato
- Organizer
  第44回日本ペプチド討論会
- Place of Presentation
  富山
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Structure of the Membrane Reconstituted Transmembiane-Juxtainembiane P eptide Neu(647-693) arid lts Interaction with Ca^<2+>/Calmodulin2007
- Author(s)
  Takeshi Sato
- Organizer
  第44回日本ペプチド討論会
- Place of Presentation
  富山
- Year and Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-19710186
[Presentation] Substrate discrimination by size-exclusion in the intramembrane protease RseP.
- Author(s)
  Hizukuri Y, Oda T, Tabata S, Tamura-Kawakami K, Oi R, Sato M, Takagi J, Akiyama Y, and Nogi T
- Organizer
  IUCr 2014 - 23rd Congress and General Assembly
- Place of Presentation
  Montreal, Canada
- Year and Date
  2014-08-05 – 2014-08-12
- Data Source
  KAKENHI-PROJECT-26291016
[Presentation] Mechanism for signaling through the membrane in activation of receptor tyrosine kinase; Molecular Targets for Diseases and Structural Life Science
- Author(s)
  Takeshi Sato
- Organizer
  The 9th International Symposium of the Institute Network
- Place of Presentation
  大阪大学
- Year and Date
  2014-06-19 – 2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-24687013
[Presentation] 細菌表層ストレス応答制御に関わる膜内切断プロテアーゼRsePのタンデムPDZドメインによる切断基質選別機構の解析
- Author(s)
  檜作洋平、小田　隆、田畑早苗、川上-田村恵子、大井里香、佐藤　衛、高木淳一、禾　晃和、秋山芳展
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26291016
[Presentation] Mechanism for signaling through the membrane in activation of receptor tyrosine kinase
- Author(s)
  Takeshi Sato
- Organizer
  Molecular Targets for Diseases and Structural Life Science, The 9th International Symposium of the Institute Network
- Place of Presentation
  大阪大学
- Year and Date
  2014-06-19 – 2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26650015

1. AIMOTO Saburo (80029967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. KAWAKAMI Toru (70273711)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. NOGI Terukazu (40379102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. AKIYAMA Yoshinori (10192460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Hojo Hironobu (00209214)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. HIZUKURI Yohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. OI Rika

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. TAKANUKI Kazunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAMURA Risako

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 篠原美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 岩岡道夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sato Takeshi 佐藤 毅

佐藤 毅 サトウ タケシ

SATO Takeshi 佐藤 毅

Research Projects

Research Products

Co-Researchers

Mechanism of Notch receptor signaling and its dependency on lipidsPrincipal Investigator

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Chemical synthesis of caveolin

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Elucidation of substrate recognition mechanism of I-CLiP in the trans- and juxta-membrane regions

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Developing strategy for uni-directional insertion of single transmembrane protein to liposomePrincipal Investigator

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Semi-synthesis of receptor tyrosine kinase and its structure and function analysisPrincipal Investigator

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Function of the transmembrane-juxtamembrane region of receptor tyrosine kinase in its activity regulationPrincipal Investigator

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Development of a method for membrane protein synthesis based on ligation chemistry

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[Journal Article] Characterizing interaction between the juxtamembrane region of the single transmembrane protein and membrane using chemically synthesized peptides2023

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[Journal Article] Threonine phosphorylation regulates the molecular assembly and signaling of EGFR in cooperation with membrane lipids.2022

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[Journal Article] Effect of hydrophobic moment on membrane interaction and cell penetration of apolipoprotein E-derived arginine-rich amphipathic α-helical peptides.2022

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[Journal Article] Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis2021

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[Journal Article] Total Synthesis and Structural Characterization of Caveolin-12021

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[Journal Article] Preparation of Selenoinsulin as a Long-Lasting Insulin Analogue2017

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[Journal Article] Total Synthesis and Antibacterial Investigation of Plusbacin A32017

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Sato Takeshi 佐藤毅

佐藤毅サトウタケシ

SATO Takeshi 佐藤毅

[Journal Article] Rational Design and Identification of Non-Peptidic Aggregation Inhibitor of Amyloid- Based on a Pharmacophore Motif Obtained from cyclo[-Lys-Leu-Val-Phe-Phe-].2014