HOSODA Kohkichi 細田弘吉

Researcher Number	90403261
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2021: 神戸大学, 医学研究科, 医学研究員 2016: 神戸大学, 医学研究科, 准教授 2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 准教授 2014: 神戸大学, 医学研究科, 准教授 2008 – 2009: Kobe University, 医学研究科, 准教授 2007: Kobe University, 大学院・医学系研究科, 准教授
Review Section/Research Field	Principal Investigator Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Neurosurgery / Cerebral neurosurgery
Keywords	Principal Investigator メタボロミクス / 脳虚血 / metabolomics / 熱ショックタンパク / ペントースリン酸経路 / NADPH / ペントースリン酸 / 脳梗塞 / cerebral ischemia / 治療薬 … More / ATMキナーゼ / 脳虚血再灌流障害 / 脳虚血再灌流 / Geranylgeranylacetone / geranylgeranylacetone / heat shock protein / stroke / ischemia reperfusion / 熱ショックタンパク質 / 虚血再灌流障害 / 熱ショック蛋白 / トランスクリプトミクス / オミクス / 脳代謝 / pentose phosphate / 一過性脳虚血 / 頚動脈狭窄症 / microarray / RT-PCA / MCA occlusion / metabolic pathway / び慢性軸策損傷 / び慢性軸索損傷 / 脳血流 / arterial spin labeling / び漫性軸索損傷 / 頭部外傷 / 拡散テンソル画像 / MRI … More Except Principal Investigator metabolome / simulation / high / aneurysm growth / thin walled region / thin wall / thick wall / growth / prediction / rupture / growing / OSI / WSS / CFD / cerebral aneurysm / 神経細胞死 / apoptosis / microRNA-21 / アポトーシス / 代謝 / マイクロRNA / 脳梗塞 / microRNA / cerebral infarction / メタボローム解析 / グリオーマ / MR spectroscopy / 2-hydroxyglutarate / IDH mutation / glutamate / IDH / glioma / 骨髄間質細胞 / 再生 / 下垂体 / 濾胞星細胞 / 動物モデル / 下垂体機能再生 / 実験脳外科学 Less

Elucidation of the role of ATM kinase pathway in cerebral ischemia-reperfusion injury and its application to new cerebral infarction therapyPrincipal Investigator
- Principal Investigator
  
  Hosoda Kohkichi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kobe University
Identification of growing cerebral aneurysms by MRI alone CFD analysis using lattice Boltzmann method
- Principal Investigator
  
  KIMURA HIDEHITO
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kobe University
Comprehennsive analysis of cerebral metabolic changes during ischemia-reperfusion by omicsPrincipal Investigator
- Principal Investigator
  
  Hosoda Kohkichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kobe University
Effect of microRNA -21 in cerebral ischemia.
- Principal Investigator
  
  Mizukawa Katsu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kobe University
Diagnostic value of tumor metabolites in metabolome analysis for glioma patients
- Principal Investigator
  
  Kohmura Eiji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kobe University
metabolome analysis of cerebral ischemia: exploration of biomarkers by comprehensive analysis of metabolic changes before and after cerebral ischemiaPrincipal Investigator
- Principal Investigator
  
  HOSODA Kohkichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University
Pituitary regeneration by bone marrow stromal cell tranplantation
- Principal Investigator
  
  TANIGUCHI MASAAKI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University
Utility of diffusion tensor imaging in the diffuse axonal injury for detecting white matter lesions and predicting long-term cognitive functionPrincipal Investigator
- Principal Investigator
  
  HOSODA Kohkichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kobe University

All 2021 2019 2018 2017 2016 2015 2014 2013 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 脳血管障害の急性期マネジメント　「虚血性脳血管障害急性期の全身管理」2014
- Author(s)
  細田弘吉
- Total Pages
  286
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-24592126
[Journal Article] Geranylgeranylacetone attenuates cerebral ischemia-reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study2021
- Author(s)
  Matsuo, Kazuya and Hosoda, Kohkichi and Tanaka, Jun and Yamamoto, Yusuke and Imahori, Taichiro and Nakai, Tomoaki and Irino, Yasuhiro and Shinohara, Masakazu and Sasayama, Takashi and Kohmura, Eiji
- Journal Title
  
  BMC Neuroscience
  
  Volume: 22 Issue: 1 Pages: 9-19
- DOI
  10.1186/s12868-021-00614-7
- NAID
  120006975748
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08994, KAKENHI-PROJECT-20K09369, KAKENHI-PROJECT-20K17968
[Journal Article] Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis2021
- Author(s)
  Hosoda Kohkichi、Imahori Taichiro、Tanaka Kazuhiro、Uno Takiko、Nakai Tomoaki、Kohta Masaaki、Fujita Atsushi、Sasayama Takashi
- Journal Title
  
  Translational Stroke Research
  
  Volume: 13 Issue: 3 Pages: 420-431
- DOI
  10.1007/s12975-021-00968-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08994, KAKENHI-PROJECT-20K17968, KAKENHI-PROJECT-22K09233
[Journal Article] Pencil Beam Presaturation Magnetic Resonance Imaging Helps to Identify Patients at Risk for Intolerance to Temporary Internal Carotid Artery Occlusion During Carotid Endarterectomy and Carotid Artery Stenting2019
- Author(s)
  Tanaka Jun、Hosoda Kohkichi、Matsuo Kazuya、Kyotani Katsusuke、Takemoto Youta、Yamamoto Yusuke、Fujita Atsushi、Kohta Masaaki、Kimura Hidehito、Sasayama Takashi、Kohmura Eiji
- Journal Title
  
  World Neurosurgery
  
  Volume: 130 Pages: e899-e907
- DOI
  10.1016/j.wneu.2019.07.033
- NAID
  120006993678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08994, KAKENHI-PROJECT-17K10897, KAKENHI-PROJECT-17K10898
[Journal Article] Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone: Preliminary Results2019
- Author(s)
  Kimura H, Hayashi K, Taniguchi M, Hosoda K, Fujita A, Seta T, Tomiyama A, Kohmura E
- Journal Title
  
  World Neurosurgery
  
  Volume: 122 Pages: e1439-e1448
- DOI
  10.1016/j.wneu.2018.11.081
- NAID
  120006840183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10826, KAKENHI-PROJECT-16K06070
[Journal Article] Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion2018
- Author(s)
  Yamamoto Yusuke、Hosoda Kohkichi、Imahori Taichiro、Tanaka Jun、Matsuo Kazuya、Nakai Tomoaki、Irino Yasuhiro、Shinohara Masakazu、Sato Naoko、Sasayama Takashi、Tanaka Kazuhiro、Nagashima Hiroaki、Kohta Masaaki、Kohmura Eiji
- Journal Title
  
  Brain Research
  
  Volume: 1687 Pages: 82-94
- DOI
  10.1016/j.brainres.2018.03.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10302, KAKENHI-PROJECT-17K09579, KAKENHI-PROJECT-17K10863, KAKENHI-PROJECT-17K10898, KAKENHI-PROJECT-18K08943
[Journal Article] Combined metabolic and transcriptional profiling identifies pentose phosphate pathway activation by HSP27 phosphorylation during cerebral ischemia.2017
- Author(s)
  Imahori T, Hosoda K, Nakai T, Yamamoto Y, Irino Y, Shinohara M, Sato N, Sasayama T, Tanaka K, Nagashima H, Kohta M, Kohmura E.
- Journal Title
  
  Neuroscience.
  
  Volume: 349 Pages: 1-16
- DOI
  10.1016/j.neuroscience.2017.02.036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10863, KAKENHI-PROJECT-15K10302
[Journal Article] Duplex-assisted carotid artery stenting without administration of contrast medium for patients with chronic kidney disease or allergic reaction.2016
- Author(s)
  Mizowaki T, Fujita A, Imahori T, Uyama A, Inoue S, Kohta M, Hamaguchi H, Sasayama T, Hosoda K, Kohmura E.
- Journal Title
  
  Neuroradiology
  
  Volume: in press Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293309
[Journal Article] Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma2016
- Author(s)
  Hiroaki Nagashima1, Kazuhiro Tanaka1*, Takashi Sasayama1, Yasuhiro Irino2, Naoko Sato1, Yukiko Takeuchi2, Katsusuke Kyotani3, Akitake Mukasa6, Katsu Mizukawa1, Junichi Sakata1, Yusuke Yamamoto1, Kohkichi Hosoda1, Tomoo Itoh4, Ryohei Sasaki5, and Eiji Kohmura1
- Journal Title
  
  Neuro-Oncology
  
  Volume: in press Pages: 1-10
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293309
[Journal Article] Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma2016
- Author(s)
  Nagashima H, Tanaka K, Sasayama T, Irino Y, Sato N, Takeuchi Y, Kyotani K, Mukasa A, Mizukawa K, Sakata J, Yamamoto Y, Hosoda K, Itoh T, Sasaki R, Kohmura E.
- Journal Title
  
  Neuro Oncol
  
  Volume: 18(11) Pages: 1559-1568
- DOI
  10.1093/neuonc/now090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05391, KAKENHI-PROJECT-26293321, KAKENHI-PROJECT-26462158, KAKENHI-PROJECT-15K09996, KAKENHI-PROJECT-16K15581, KAKENHI-PROJECT-16K15641
[Journal Article] Two Cases of Cerebral Infarction due to Focal Irradiation for Glioma in Adults2015
- Author(s)
  Minami N, Mizukawa K, Iwahashi H, Nagashima H, Tanaka K, Sasayama T, Hosoda K, Mukumoto N, Sasaki R, Kohmura E.
- Journal Title
  
  Neurological Surgery 脳神経外科
  
  Volume: 43 Issue: 4 Pages: 344-351
- DOI
  10.11477/mf.1436203018
- ISSN
  0301-2603, 1882-1251
- Year and Date
  2015-04-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293309, KAKENHI-PROJECT-26462158, KAKENHI-PROJECT-26462181, KAKENHI-PROJECT-25462258
[Journal Article] 無症候性頸動脈狭窄症に対する手術治療の現状と課題2015
- Author(s)
  細田弘吉，藤田敦史，木村英仁，甲田将章，阿久津宣行，甲村英二
- Journal Title
  
  脳卒中の外科
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592126
[Journal Article] Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.2015
- Author(s)
  Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, Masui K, Gini B, Yang H, Hosoda K, Sasaki R, Mischel PS, Kohmura E.
- Journal Title
  
  J Clin Invest
  
  Volume: 125 Issue: 4 Pages: 1591-602
- DOI
  10.1172/jci78239
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462158, KAKENHI-PROJECT-26830073, KAKENHI-PROJECT-15K09996, KAKENHI-PROJECT-26462181, KAKENHI-PROJECT-25462258, KAKENHI-PROJECT-25670535, KAKENHI-PROJECT-25293265, KAKENHI-PROJECT-25293309
[Journal Article] Use of Heparinized Autologous Blood for Intraoperative Rinsing and Storage of Vascular Grafts2015
- Author(s)
  Kimura H, Hosoda K, Kohmura E
- Journal Title
  
  Neurological Surgery 脳神経外科
  
  Volume: 43 Issue: 2 Pages: 109-115
- DOI
  10.11477/mf.1436202964
- ISSN
  0301-2603, 1882-1251
- Year and Date
  2015-02-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293309
[Journal Article] Subarachnoid Hemorrhage Due to Rupture of an Intracavernous Carotid Artery Aneurysm Coexisting with a Prolactinoma under Cabergoline Treatment.2014
- Author(s)
  Akutsu N, Hosoda K, Ohta K, Tanaka H, Taniguchi M, Kohmura E.
- Journal Title
  
  J Neurol Surg Rep
  
  Volume: 75 Issue: 01 Pages: e73-e76
- DOI
  10.1055/s-0033-1364166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293309
[Journal Article] Utility of 320- detector row ct for diagnosis and therapeutic strategy for paraclinoid and intracavernous aneurysms.2014
- Author(s)
  Inoue, S., Hosoda, K., Fujita, A., Ohno, Y., Fujii, M., Sugimura, K., and Kohmura, E.
- Journal Title
  
  Acta Neurochir (Wien)
  
  Volume: 156 Issue: 3 Pages: 505-514
- DOI
  10.1007/s00701-014-1996-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592126, KAKENHI-PROJECT-25293309
[Journal Article]2013
- Author(s)
  Tanaka H, Sasayama T, Tanaka K, Nakamizo S, Nishihara M, Mizukawa K, Kohta M, Koyama J, Miyake S, Taniguchi M, Hosoda K, Kohmura E
- Journal Title
  
  J Neurooncol
  
  Volume: 111(3) Issue: 3 Pages: 273-83
- DOI
  10.1007/s11060-012-1027-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591610, KAKENHI-PROJECT-24791501, KAKENHI-PROJECT-25293309, KAKENHI-PROJECT-25462258
[Journal Article]2013
- Author(s)
  Nakamizo S, Sasayama T, Shinohara M, Irino Y, Nishiumi S, Nishihara M, Tanaka H, Tanaka K, Mizukawa K, Itoh T, Taniguchi M, Hosoda K, Yoshida M, Kohmura E
- Journal Title
  
  J Neurooncol
  
  Volume: 113(1) Issue: 1 Pages: 65-74
- DOI
  10.1007/s11060-013-1090-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591610, KAKENHI-PROJECT-24791501, KAKENHI-PROJECT-25293309, KAKENHI-PROJECT-25462258
[Journal Article] Preoperative detection of the facial nerve by high-field magnetic resonance imaging in patients with vestibular schwannoma2013
- Author(s)
  Nakai T, Yamamoto H, Tanaka K, Koyama J, Fujita A, Taniguchi M, Hosoda K, Kohmura E
- Journal Title
  
  Neuroradiology
  
  Volume: 55 Issue: 5 Pages: 615-20
- DOI
  10.1007/s00234-013-1156-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293309
[Journal Article] Diffusion tensor imaging in acute stage is useful to detect the white matter lesions and to predict the long-term cognitive prognosis of mild to moderate traumatic brain injury in adults.2011
- Author(s)
  Matsushita M, Hosoda K, Naitoh Y, Yamashita H, Kohmura E
- Journal Title
  
  J Neurosurg in press
- Data Source
  KAKENHI-PROJECT-19591674
[Journal Article] Diffusion tensor imaging in acute stage is useful to detect the white matter lesions and to predict the long-term cognitive prognosis of mild to moderate traumatic brain injury in adults2011
- Author(s)
  Matsushita, Hosoda, et.al.
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591674
[Journal Article] Clinical application of Arterial Spin Labeling MRI in patients with carotid stenosis -quantitative comparative study with SPECT-2011
- Author(s)
  Uchihashi Y, Hosoda K, Zimine I, Fujita A, Fujii M, Sugimura K, Kohmura E
- Journal Title
  
  AJNR Am J Neuroradiol in press
- Data Source
  KAKENHI-PROJECT-19591674
[Journal Article] Clinical application of Arterial Spin Labeling MRI in patients with carotid stenosis -quantitative comparative study with SPECT-2011
- Author(s)
  Ushihashi, Hosoda, et.al
- Journal Title
  
  American Journal of Neuroradiology
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] 脳虚血再灌流障害におけるオミクス解析2021
- Author(s)
  細田弘吉　中井友昭　今堀太一郎　山本祐輔　田中潤　松尾和哉　甲田将章　藤田敦史　田中一寛　篠山隆司　甲村英二
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 脳虚血再灌流障害のオミクス解析2021
- Author(s)
  細田弘吉，中井友昭，今堀太一郎，山本祐輔，田中潤，松尾和哉，甲田将章，藤田敦史，田中一寛，篠山隆司，甲村英二
- Organizer
  第46回日本脳卒中学会学術集会　2021年3月13日　福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Activate the Pentose Phosphate Pathway to Reduce the Cerebral Ischemia/Reperfusion Injury: The Impact of Heat Shock Protein 27 Phosphorylation2019
- Author(s)
  Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Takashi Sasayama, Eiji Kohmura
- Organizer
  International Stroke Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 脳虚血再灌流障害に対する Heat shock protein 27リン酸化誘導による神経保護治療：メタボロミクス研究から治療応用へ．2019
- Author(s)
  9.松尾和哉, 細田弘吉, 田中潤, 山本祐輔, 今堀太一郎, 中井友昭, 入野康宏, 篠原正和, 篠山隆司, 甲村英二．
- Organizer
  日本脳神経外科学会第78回学術総会　2019年10月9日　大阪国際会議場（グランキューブ大阪）
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 脳虚血再灌流障害に対する Heat shock protein 27リン酸化誘導による神経保護治療：オミクス研究から治療へ．特別シンポジウム1『時間で追う脳虚血の病態と治療:1急性期』2019
- Author(s)
  13.松尾和哉, 細田弘吉, 田中潤, 山本祐輔, 今堀太一郎, 中井友昭, 入野康宏, 篠原正和, 篠山隆司, 甲村英二．
- Organizer
  第62回日本脳循環代謝学会学術集会2019年11月29日　江陽グランドホテル（仙台）
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Phosphorylation of Heat Shock Protein 27 Leads to Activation of Pentose Phosphate Pathway and Protection from Cerebral Ischemia-Reperfusion Injury2019
- Author(s)
  3.Matsuo K, Hosoda K, Tanaka J, Yamamoto Y, Imahori T, Nakai T, Irino Y, Shinohara M, Sasayama T, Kohmura E
- Organizer
  Brain & Brain PET 2019, Yokohama (Japan)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 虚血再灌流時のHeat shock protein 27リン酸化によるペントースリン酸経路亢進: オミクス研究から治療応用へ2019
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  第44回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Heat shock protein 27リン酸化誘導による脳虚血再灌流時の神経保護:オミクス研究から臨床応用へ2019
- Author(s)
  7.松尾和哉，細田弘吉，田中潤，山本祐輔，今堀太一郎，中井友昭，入野康宏，篠原正和，篠山隆司，甲村英二．
- Organizer
  第20回日本分子脳神経外科学会　2019年8月9日　秋葉原コンベンションホール（東京）
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Upregulation of Pentose Phosphate Pathway after Focal Cerebral Ischemia/Reperfusion Injury in Rat Cerebral Cortex: The Impact of Heat Shock Protein 27 Phosphorylation2018
- Author(s)
  Kazuya Matsuo, Kohkichi Hosoda, Jun Tanaka1, Yusuke Yamamoto, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Eiji Kohmura
- Organizer
  International Stroke Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] 虚血後再灌流による脳皮質でのペントースリン酸経路の賦活化 -オミクス解析による分析とHeat shock protein 27の関与-2018
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  第19回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 虚血再灌流による脳皮質ペントースリン酸経路の亢進　オミクス研究を基に探るHeat shock protein 27 の役割2018
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  第62回日本脳循環代謝学会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] 虚血再灌流による脳皮質でのペントースリン酸経路の賦活化オミクス解析による分析と Heat shock protein 27 の役割2018
- Author(s)
  松尾和哉、細田弘吉、田中潤、山本祐輔、今堀太一郎、中井友昭、入野康宏、篠原正和、篠山隆司、甲村英二
- Organizer
  日本脳神経外科学会第77回学術総会
- Data Source
  KAKENHI-PROJECT-18K08994
[Presentation] Prediction of Cerebral Aneurysm Growth using Our Novel Computational Fluid Dynamics Tool2017
- Author(s)
  Hidehito Kimura, Kohsuke Hayashi, Kohkichi Hosoda, Atsushi Fujita, Masaaki Taniguchi, Akio Tomiyama, Eiji Kohmura
- Organizer
  第32回日本脳神経外科国際学会フォーラム
- Data Source
  KAKENHI-PROJECT-17K10826
[Presentation] Prediction of Cerebral Aneurysm Growth Using Novel Magnetic Resonance Imaging-based Computational Fluid Dynamics Tool2017
- Author(s)
  Hidehito Kimura, Kohsuke Hayashi, Kohkichi Hosoda, Atsushi Fujita, Masaaki Taniguchi, Akio Tomiyama, Eiji Kohmura
- Organizer
  International stroke conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10826
[Presentation] MRA単独CFD解析による脳動脈瘤の増大予測2017
- Author(s)
  木村英仁, 林　公祐, 細田弘吉, 藤田敦史, 冨山明男, 甲村英二
- Organizer
  Stroke 2017（第46回脳卒中の外科学会）
- Data Source
  KAKENHI-PROJECT-17K10826
[Presentation] Combined Metabolic And Transcriptional Profiling Identifies Pentose Phosphate Pathway Activation by Heat Shock Protein 27 Phosphorylation During Cerebral Ischemia2017
- Author(s)
  YUSUKE YAMAMOTO, Kohkichi Hosoda, Jun Tanaka, Taichiro Imahori, Tomoaki Nakai, Yasuhiro Irino, Masakazu Shinohara, Naoko Sato, Eiji Kohmura
- Organizer
  International Stroke Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] 脳組織のオミクス解析による脳虚血中HSP27リン酸化を介するペントースリン酸経路活性化の同定2016
- Author(s)
  山本祐輔、細田弘吉、入野康宏、篠原正和、今堀太一郎、田中潤、中井友昭、甲村英二
- Organizer
  第59回日本脳循環代謝学会学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] 虚血脳組織のオミクス解析による脳虚血中HSP27リン酸化を介するペントースリン酸経路活性化の同定2016
- Author(s)
  山本祐輔、細田弘吉、入野康宏、篠原正和、今堀太一郎、田中潤、中井友昭、甲村英二
- Organizer
  日本脳神経外科学会第 75 回学術総会
- Place of Presentation
  福岡
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] Metabolomic Analysis of Ischemic Brain Tissue to Explore Specific Metabolic Pathway Assosiated with Cerebral Ischemia2016
- Author(s)
  Yusuke Yamamoto, Kohkichi Hosoda, Yasuhiro Irino, Jun Tanaka, Taichiro Imahori, Tomoaki Nakai, Eiji Kohmura
- Organizer
  International Stroke Conference 2016
- Place of Presentation
  Los Angeles, California, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] METABOLIC AND TRANSCRIPTIONAL PROFILING OF ACUTE CEREBRAL ISCHEMIA IN RATS: PART 1. CHANGES 380 OF BRAIN TISSUE2015
- Author(s)
  T. Imahori, K. Hosoda, Y. Irino, T. Nakai, Y. Yamamoto, J. Tanaka, E. Kohmura
- Organizer
  Brain 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] METABOLIC PROFILING TO IDENTIFY DISTINCT CHANGES ASSOCIATED WITH ISCHEMIC CEREBROVASCULAR EVENTS 385 IN CAROTID STENOSIS2015
- Author(s)
  T. Nakai, K. Hosoda, T. Imahori, M. Shinohara, Y. Irino, M. Yoshida, E. Kohmura
- Organizer
  Brain 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] METABOLOMICS PROFILING OF ACUTE ISCHEMIA IN RATS: PARTII. METABOLIC CHANGES OF BLOOD PLASMA2015
- Author(s)
  Y. Yamamoto, K. Hosoda, T. Imahori, Y. Irino, J.U.N. Tanaka, T. Nakai, E.I.J.I. Kohmura
- Organizer
  Brain 2015
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2015-06-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] 急性期脳虚血代謝物変動の包括的メタボローム解析によるバイオマーカー探索2015
- Author(s)
  今堀太一郎、細田弘吉、入野康宏、山本祐輔、田中潤、中井友昭，甲村英二
- Organizer
  日本脳神経外科学会第 74 回学術総会
- Place of Presentation
  札幌
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K10302
[Presentation] Metabolomics profiling in cerebral ischemic rats using GC-MS for identification of blood biomarkers associated with acute ischemic stroke2014
- Author(s)
  T.Imahori, K.Hosoda, T.Nakai, Y.Iriono, E.Kohmura
- Organizer
  The 2nd International Conference on Heart & Brain
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] Metabolomics study for new candidate biomarkers in cerebral ischemia2014
- Author(s)
  T.Nakai, K.Hosoda, T.Imahori, S.Nishiumi, M.Yoshida, E.Kohmura
- Organizer
  The 2nd International Conference on Heart & Brain
- Place of Presentation
  Paris
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] メタボロミクス解析による新たな脳虚血バイオマーカー探求2013
- Author(s)
  中井　友昭、細田　弘吉、今堀　太一郎、甲村　英二、西海　信、吉田　優
- Organizer
  日本脳神経外科学会第72回学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] メタボロミクス解析を用いた頚動脈内膜剥離術中の脳代謝物変化による新たな脳虚血バイオマーカーの探索2013
- Author(s)
  今堀　太一郎、中井　友昭、細田　弘吉、西海　信、吉田　優、甲村　英二
- Organizer
  第25回日本脳循環代謝学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] メタボロミクス解析を用いた新たな脳虚血バイオマーカーの探求2013
- Author(s)
  中井　友昭、細田　弘吉、今堀　太一郎、西海　信、吉田　優、甲村　英二
- Organizer
  第25回日本脳循環代謝学会総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] 内頚動脈内膜剥離術中の一時的脳血流遮断時の脳代謝変化について -メタボロミクス解析を用いた研究-2013
- Author(s)
  中井友昭、細田弘吉、今堀太一郎、甲村英二
- Organizer
  Stroke2013
- Place of Presentation
  グランドプリンスホテル新高輪（東京都）
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] Diffusion tensor imaging in the acute stage of mild to moderate head injury is useful to detect the white matter lesions and to predict the long-term prognosis.2010
- Author(s)
  細田弘吉, 松下誠, 甲村英二
- Organizer
  The 2nd International Congress of Asia Oceania Neurotrauma Society
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] Clinical application of Arterial Spin Labeling MRI in patients with carotid stenosis -quantitative comparative study with SPECT-.2010
- Author(s)
  Uchihashi Y, Hosoda K, Zimine I, Yamamoto D, Aoyama N, Fujii, M, Kohmura E
- Organizer
  The 60th Congress of Neurological Surgeons
- Place of Presentation
  San Frabcisoco
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] ASL(QUASAR)法を用いた無侵襲脳灌流画像撮像法の臨床応用2010
- Author(s)
  内橋義人, 細田弘吉, Ivan Zimine, 藤井康彦, 青山信和, 甲村英二
- Organizer
  第39回脳卒中の外科学会総会シンポジウム:脳卒中の日常臨床における脳循環代謝画像:有用性と限界
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] Arterial Spin Labeling (ASL)-MRIによる脳灌流画像の臨床応用-SPECTとの比較-2009
- Author(s)
  内橋義人, 細田弘吉, 藤田敦史, イワン・ジミー, 藤田敦史, 井上悟志, 青山信和, 神澤匡数, 川光秀昭, 青木一, 藤井正彦, 甲村英二
- Organizer
  第38回日本神経放射線学会シンポジウムIII機能画像の有用性と限界
- Place of Presentation
  水戸
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] Comparison of CBF Measurement by ASL and SPECT in Patients with Carotid Stenosis.2009
- Author(s)
  Uchihashi Y, Hosoda K, Zimine I, Fujita A, Inoue S, Aihara H, Kawamitsu H, Aoyama N, Aoki H, Fujii M, Kohmura E
- Organizer
  International Society for magnetic resonance in medicine (ISMRM) 17th Scientific Meeting & Exhibition
- Place of Presentation
  Honolulu
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] ASL-MRIによる新しい脳灌流画像の臨床応用ーSPECTとの比較ー2009
- Author(s)
  内橋義人, 細田弘吉, 藤田敦史, イワン・ジミー, 青山信和, 川光秀昭, 藤井正彦, 井上悟志, 甲村英二
- Organizer
  第38回脳卒中の外科学会総会シンポジウム:脳卒中画像診断の最先端
- Place of Presentation
  松江
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] 拡散テンソル画像による頭部外傷における白質病変検出の試みと予後との関連2008
- Author(s)
  松下誠, 山本大輔, 太田耕平, 原淑恵, 山下晴央, 細田弘吉, 甲村英二
- Organizer
  第31回日本神経外傷学会シンポジウム3:高次機能障害-病態の解明-
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] Detection of neurological (neuropathological) changes in white matter and evaluation of prognosis by diffusion tensor images.2008
- Author(s)
  松下誠, 原淑恵, 山下晴央, 細田弘吉, 甲村英二
- Organizer
  The 26th Annual National Neurotrauma Symposium
- Place of Presentation
  Orlando
- Data Source
  KAKENHI-PROJECT-19591674
[Presentation] Metabolomic Profiling of Middle Cerebral Artery Occlusion Models in the Rats Using GC-MS for Exploration of Blood Metabolic Biomarkers Associated with Acute Cerebral Ischemia
- Author(s)
  Imahori T, Hosoda K, Nakai T, Irino Y, Kohmura E
- Organizer
  9th World Stroke Congress
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] グリオーマにおける脳脊髄液を用いたメタボローム解析
- Author(s)
  篠山隆司、中溝聡、篠原正和、入野康弘、西海信、田中宏知、田中一寛、水川克、伊藤智雄、細田弘吉、吉田優、甲村英二
- Organizer
  第2回がんと代謝研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-25293309
[Presentation] グリオーマにおける脳脊髄液を用いたメタボローム解析
- Author(s)
  篠山隆司、中溝聡、篠原正和、入野康弘、西海信、田中宏知、田中一寛、水川克、細田弘吉、吉田優、甲村英二
- Organizer
  第2回がんと代謝研究会
- Place of Presentation
  東京
- Year and Date
  2014-07-10 – 2014-07-11
- Data Source
  KAKENHI-PROJECT-26462158
[Presentation] ラット中大脳動脈閉塞モデルのメタボローム解析による急性期脳虚血の代謝変動：Part I 脳組織の変化
- Author(s)
  今堀太一郎、細田弘吉、入野康宏、山本祐輔、田中潤、中井友昭、甲村英二
- Organizer
  第40回日本脳卒中学会総会
- Place of Presentation
  広島
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] Utility of 320-detector row CT for diagnosis and therapeutic strategy for paraclinoid and intracavernous aneurysms
- Author(s)
  Hosoda K, Inoue S, Ohno Y, Fujii M, Sugimura K, Kohmura E
- Organizer
  9th World Stroke Congress
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-10-22 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] 当院における悪性神経膠腫再発例に対するアバスチン(Bevacizumab)療法
- Author(s)
  水川克、篠山隆司、田中一寛、長嶋宏明、堀達雄、細田弘吉、甲村英二
- Organizer
  第73回日本脳神経外科学会総会
- Place of Presentation
  東京
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-26462158
[Presentation] ラット中大脳動脈閉塞モデルのメタボローム解析による急性期脳虚血時の代謝変化 Part II: 血漿中の変化
- Author(s)
  細田弘吉, 今堀太一郎, 入野康宏, 山本祐輔, 田中潤, 中井友昭, 甲村英二
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] 脳虚血代謝変動のメタボローム解析によるバイオマーカーの探索
- Author(s)
  細田弘吉
- Organizer
  第40回日本脳卒中学会総会
- Place of Presentation
  広島
- Year and Date
  2015-03-26 – 2015-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] 脳内出血を来たした滑膜肉腫の脳転移の１例
- Author(s)
  水川　克、堀　達雄、森　達也、鵜山　淳、南　徳明、長嶋宏明、田中一寛、篠山隆司、細田弘吉、甲村英二
- Organizer
  第32回日本脳腫瘍学会
- Place of Presentation
  東京
- Year and Date
  2014-11-30 – 2014-12-02
- Data Source
  KAKENHI-PROJECT-26462158
[Presentation] ラット中大脳動脈閉塞モデルのメタボローム解析による急性期脳虚血時の代謝変化 Part I 脳組織の変化
- Author(s)
  今堀太一郎、細田弘吉、入野康宏、山本祐輔、田中潤、中井友昭，甲村英二
- Organizer
  第26回日本脳循環代謝学会総会
- Place of Presentation
  岡山
- Year and Date
  2014-11-21 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] ラット中大脳動脈閉塞モデルの脳組織および血漿メタボローム解析（GC/MS）による急性期脳虚血バイオマーカー探索
- Author(s)
  今堀太一郎, 細田弘吉, 山本祐輔, 田中潤, 中井友昭, 入野康宏, 甲村英二
- Organizer
  日本脳神経外科学会第73回学術総会
- Place of Presentation
  東京（グランドプリンスホテル新高輪）
- Year and Date
  2014-10-09 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-24592126
[Presentation] ラット中大脳動脈閉塞モデルのメタボローム解析による急性期脳虚血の代謝変動 PartⅡ 血漿中の変化
- Author(s)
  山本祐輔、細田弘吉、入野康宏、今堀太一郎、田中潤、中井友昭，甲村英二
- Organizer
  第40回日本脳卒中学会総会
- Place of Presentation
  広島
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24592126

1. KOHMURA Eiji (30225388)

# of Collaborated Projects: 7 results

# of Collaborated Products: 58 results
2. SASAYAMA Takashi (10379399)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
3. TANAKA Kazuhiro (70467661)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. MIZUKAWA Katsu (80403260)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. 篠原正和 (80437483)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
6. FUJII Masahiko (00228959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. KOYAMA Junji (00594508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UCHIHASHI Yoshito (80605999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YOSHIDA Masaru (00419475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. TANIGUCHI MASAAKI (60346195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KONDOH Takeshi (50273769)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SASAKI Ryohei (30346267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. KIMURA HIDEHITO (90514753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. 小西淳也 (40403290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 西原賢在 (20452493)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 林公祐 (60455152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

HOSODA Kohkichi 細田 弘吉

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Co-Researchers

Elucidation of the role of ATM kinase pathway in cerebral ischemia-reperfusion injury and its application to new cerebral infarction therapyPrincipal Investigator

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Identification of growing cerebral aneurysms by MRI alone CFD analysis using lattice Boltzmann method

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Comprehennsive analysis of cerebral metabolic changes during ischemia-reperfusion by omicsPrincipal Investigator

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Effect of microRNA -21 in cerebral ischemia.

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Diagnostic value of tumor metabolites in metabolome analysis for glioma patients

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metabolome analysis of cerebral ischemia: exploration of biomarkers by comprehensive analysis of metabolic changes before and after cerebral ischemiaPrincipal Investigator

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Pituitary regeneration by bone marrow stromal cell tranplantation

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Utility of diffusion tensor imaging in the diffuse axonal injury for detecting white matter lesions and predicting long-term cognitive functionPrincipal Investigator

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[Book] 脳血管障害の急性期マネジメント 「虚血性脳血管障害急性期の全身管理」2014

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[Journal Article] Geranylgeranylacetone attenuates cerebral ischemia-reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study2021

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[Journal Article] Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis2021

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[Journal Article] Pencil Beam Presaturation Magnetic Resonance Imaging Helps to Identify Patients at Risk for Intolerance to Temporary Internal Carotid Artery Occlusion During Carotid Endarterectomy and Carotid Artery Stenting2019

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[Journal Article] Detection of Hemodynamic Characteristics Before Growth in Growing Cerebral Aneurysms by Analyzing Time-of-Flight Magnetic Resonance Angiography Images Alone: Preliminary Results2019

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HOSODA Kohkichi 細田弘吉

[Book] 脳血管障害の急性期マネジメント　「虚血性脳血管障害急性期の全身管理」2014

[Journal Article] 無症候性頸動脈狭窄症に対する手術治療の現状と課題2015