Kawaguchi Makiko 川口真紀子

… Alternative Names

川口真紀子カワグチマキコ

KAWAGUCHI Makiko 川口真紀子

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Researcher Number	90405598
Other IDs
Affiliation (Current)	2025: 愛媛大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 宮崎大学, 医学部, 助教 2022 – 2023: 宮崎大学, 医学部, 助教 2011 – 2020: 宮崎大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / General physiology / Basic Section 50010:Tumor biology-related / Pathological medical chemistry Except Principal Investigator General anatomy (including histology/embryology) / Experimental pathology
Keywords	Principal Investigator セリンプロテアーゼ / PAR-2 / セリンプロテアーゼインヒビター / 潰瘍性大腸炎 / ST14 / 大腸癌 / マトリプターゼ / 腸管上皮 / 膜結合型セリンプロテアーゼ / SPINT-2 … More / tufting enteropathyy / SPINT2 / EpCAM / prostasin / matriptase / HAI-2 / HAI-1 / 腸管発癌 / p38MAPK / 表皮 / 病理学 / プロテアーゼ / 上皮機能 / 細胞膜結合型セリンプロテアーゼインヒビター / 腸上皮 … More Except Principal Investigator 細胞組織化学 / 解剖学 / ラット肝臓 / miR-122 / in situ hybidization / 凍結切片 / パラフィン切片 / ラット肝切除モデル / miR122 / microRNA / 28S rRNA / in situ hybridization / 蛍光共鳴エネルギー移動 / 蛍光 / マイクロRNA / in situハイブリダイゼーション / 癌 / マトリプターゼ / HAI-2 / 発がん / HAI / 遺伝子改変マウス / 浸潤・転移 / がん細胞微小環境 / 上皮組織 / HAI-1 / 浸潤転移 / 発癌 / 上皮細胞 / プロテアーゼインヒビター / プロテアーゼ / 実験病理学 / 病理学 Less

先天性ナトリウム下痢症の発症メカニズム解明と治療法の開発Principal Investigator
- Principal Investigator
  
  川口真紀子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  University of Miyazaki
大腸発癌におけるマトリプターゼ発現の意義に関する研究Principal Investigator
- Principal Investigator
  
  川口真紀子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  University of Miyazaki
Regulation of membrane-anchored serine protease activities and its significance in epithelial pathophysiologyPrincipal Investigator
- Principal Investigator
  
  Kawaguchi Makiko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  University of Miyazaki
The analysis of microRNA localization using fluorescence resonance energy transfer based in situ hybridization
- Principal Investigator
  
  Hishikawa Yoshitaka
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  University of Miyazaki
Roles of HAI-1, a membrane-anchored serine protease inhibitor, in intestinal carcinogenesis through regulating pericellular proteolysisPrincipal Investigator
- Principal Investigator
  
  Kawaguchi Makiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
Roles of HAI-1, a membrane-anchored serine protease inhibitor, in maintaining keratinocyte morphologyPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Makiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  University of Miyazaki
Regulation of protease activities on the epithelial cell surface and its significance in epithelial disorders.
- Principal Investigator
  
  KATAOKA HIROAKI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Miyazaki
Role of membrane-bound serine protease inhibitor in maintaining integrity of intestinal epitheliumPrincipal Investigator
- Principal Investigator
  
  KAWAGUCHI Makiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  University of Miyazaki

All 2023 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Matriptase-2 regulates iron homeostasis primarily by setting the basal levels of hepatic hepcidin expression through a nonproteolytic mechanism2023
- Author(s)
  Enns CA, Weiskopf T, Zhang RH, Wu J, Jue S, Kawaguchi M, Kataoka H, Zhang AS
- Journal Title
  
  J Biol Chem
  
  Volume: 299 Issue: 10 Pages: 105238-105238
- DOI
  10.1016/j.jbc.2023.105238
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07154
[Journal Article] Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM2023
- Author(s)
  Szabo R, Kawaguchi M, Kataoka H, Bugge TH.
- Journal Title
  
  Development
  
  Volume: 150 Issue: 17
- DOI
  10.1242/dev.201801
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07154
[Journal Article] Protease‐activated receptor‐2 accelerates intestinal tumor formation through activation of nuclear factor‐κB signaling and tumor angiogenesis in Apc Min/+ mice2020
- Author(s)
  Kawaguchi Makiko、Yamamoto Koji、Kataoka Hiroaki、Izumi Aya、Yamashita Fumiki、Kiwaki Takumi、Nishida Takahiro、Camerer Eric、Fukushima Tsuyoshi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 4 Pages: 1193-1202
- DOI
  10.1111/cas.14335
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-17K08764, KAKENHI-PROJECT-20K18483, KAKENHI-PROJECT-18K06964
[Journal Article] Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine2019
- Author(s)
  Kawaguchi Makiko、Yamamoto Koji、Takeda Naoki、Fukushima Tsuyoshi、Yamashita Fumiki、Sato Katsuaki、Kitamura Kenichiro、Hippo Yoshitaka、Janetka James W.、Kataoka Hiroaki
- Journal Title
  
  Communications Biology
  
  Volume: 2 Issue: 1 Pages: 11-11
- DOI
  10.1038/s42003-018-0255-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06964, KAKENHI-PROJECT-18K08237, KAKENHI-PROJECT-18K17029, KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-17K08764
[Journal Article] 腸上皮の正常性維持に不可欠な細胞膜結合セリンプロテアーゼ制御機構2019
- Author(s)
  山本晃士、川口真紀子、片岡寛章
- Journal Title
  
  メディカルサイエンスダイジェスト
  
  Volume: 45 Pages: 622-625
- Data Source
  KAKENHI-PROJECT-18K06964
[Journal Article] Aberrant methylation and silencing of the SPINT2 gene in high-grade gliomas.2018
- Author(s)
  Fukushima T, Kawaguchi M, Yamamoto K, Yamashita F, Izumi A, Kaieda T, Takezaki Y, Itoh H, Takeshima H, Kataoka H
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 9 Pages: 2970-2979
- DOI
  10.1111/cas.13732
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08764, KAKENHI-PROJECT-18K06964, KAKENHI-PROJECT-16H05175
[Journal Article] Hepatocyte growth factor activator inhibitor type-2 (HAI-2)/SPINT2 contributes to invasive growth of oral squamous cell carcinoma cells.2018
- Author(s)
  Yamamoto K, Kawaguchi M, ShimomuraT, Izumi A, Konari K, Honda A, Lin CY, Johnson MD, Yamashita Y, FukushimaT and Kataoka K.
- Journal Title
  
  Oncotarget.
  
  Volume: 9 Issue: 14 Pages: 11691-11706
- DOI
  10.18632/oncotarget.24450
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08311, KAKENHI-PROJECT-18K17029, KAKENHI-PROJECT-16H05175
[Journal Article] Deregulated matriptase activity in oral squamous cell carcinoma promotes the infiltration of cancer‐associated fibroblasts by paracrine activation of protease‐activated receptor 2.2017
- Author(s)
  Kanemaru A, Yamamoto K, Kawaguchi M, Fukushima T, Lin C-Y, Johnson MD, Camerer E, Kataoka H.
- Journal Title
  
  International Journal of Cancer
  
  Volume: 140 Issue: 1 Pages: 130-141
- DOI
  10.1002/ijc.30426
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-15K08311
[Journal Article] Prognostic significance of hepatocyte growth factor activator inhibitor type 1 (HAI-1)/SPINT1 immunoreactivity in pancreatic ductal adenocarcinoma.2017
- Author(s)
  Sakugawa C, Haruyama Y, Tanaka H, Fukushima T, Kawaguchi M, Kataoka H
- Journal Title
  
  BMC Res Notes
  
  Volume: 10:674 Issue: 1 Pages: 1-7
- DOI
  10.1186/s13104-017-3014-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-15K08311
[Journal Article] Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the ApcMin/+ model.2016
- Author(s)
  Kawaguchi M, Yamamoto K, Kanemaru A, Tanaka H, Umezawa K, Fukushima T, Kataoka H.
- Journal Title
  
  Oncotarget
  
  Volume: ７ Issue: 42 Pages: 68614-68622
- DOI
  10.18632/oncotarget.11863
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05175, KAKENHI-PROJECT-15K08311
[Journal Article] Ghrelin administration suppresses inflammation-associated colorectal carcinogenesis in mice2015
- Author(s)
  Kawaguchi M, Kanemaru A, Fukushima T, Yamamoto K, Tanaka H, Haruyama Y, Itoh H, Matsumoto N, Kangawa K, Nakazato M, Kataoka H
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Issue: 9 Pages: 1130-1136
- DOI
  10.1111/cas.12725
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08311, KAKENHI-PROJECT-26670419, KAKENHI-PROJECT-24390099, KAKENHI-PROJECT-25293216
[Journal Article] Hepatocyte growth factor activator inhibitor type 1 maintains the assembly of keratin into desmosomes in keratinocytes by regulating protease-activated receptor 2-dependent p38 signaling2015
- Author(s)
  Kawaguchi M, Kanemaru A, Sawaguchi A, Yamamoto K, Baba T, Lin C-Y, Johnson MD, Fukushima T, Kataoka H
- Journal Title
  
  Am. J. Pathol.
  
  Volume: 185 Issue: 6 Pages: 1610-1623
- DOI
  10.1016/j.ajpath.2015.02.009
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08311, KAKENHI-PROJECT-24390099
[Journal Article] Aberrant expression of monocarboxylate transporter 4 (MCT4) in tumor cells predicts an unfavorable outcome in patients with hepatocellular carcinoma.2014
- Author(s)
  Ohno A, Yorita K, Haruyama Y, Kondo K, Kato A, Ohtomo T, Kawaguchi M, Marutuska K, Chijiiwa K, Kataoka H
- Journal Title
  
  Liver International
  
  Volume: 34 Issue: 6 Pages: 942-952
- DOI
  10.1111/liv.12466
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390099, KAKENHI-PROJECT-25860270
[Journal Article] Loss of HAI-1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model.2014
- Author(s)
  Ye J, Kawaguchi M, Haruyama Y, Kanemaru A, Fukushima T, Yamamoto K, Lin C-Y, Kataoka H
- Journal Title
  
  Cancer Science
  
  Volume: 105 Issue: 1 Pages: 44-51
- DOI
  10.1111/cas.12306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390099, KAKENHI-PROJECT-24590486, KAKENHI-PROJECT-25860166
[Journal Article] Mechanisms of Hepatocyte Growth Factor Activation in Cancer2014
- Author(s)
  Kawaguchi M, Kataoka H
- Journal Title
  
  Cancers
  
  Volume: 6 Issue: 4 Pages: 1890-1904
- DOI
  10.3390/cancers6041890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860166
[Journal Article] Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis2013
- Author(s)
  Hoshiko S, Kawaguchi M, Fukushima T, Haruyama Y, Yorita Y, Tanaka H, Seiki M, Inatsu H, Kitamura K, Kataoka H
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 2659-2670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250
[Journal Article] Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells.2013
- Author(s)
  Kohama K, Kawaguchi M, Fukushima T, Lin C-Y, Kataoka H.
- Journal Title
  
  Human Cell
  
  Volume: 25 Issue: 4 Pages: 100-110
- DOI
  10.1007/s13577-012-0055-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250, KAKENHI-PROJECT-24590486
[Journal Article] Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells.2013
- Author(s)
  Kohama K, Kawaguchi M, Fukushima T, Lin C-Y, Kataoka H
- Journal Title
  
  Human Cell
  
  Volume: 25 Pages: 100-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390099
[Journal Article] Regulation of pericellular proteolysis by hepatocyte growth factor activator inhibitor type 1 (HAI-1) in trophoblast cells2013
- Author(s)
  Kohama K, Kawaguchi M, Fukushima T, Lin C-Y, Kataoka H
- Journal Title
  
  Hum. Cell
  
  Volume: 25 Pages: 100-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250
[Journal Article] Hepatocyte growth factor activator inhibitor type 1 is a suppressor of intestinal tumorigenesis.2013
- Author(s)
  Hoshiko S, Kawaguchi M, Fukushima T, Haruyama Y, Yorita K, Tanaka H, Seiki M, Inatsu H, Kitamura K, Kataoka H.
- Journal Title
  
  Cancer Res.
  
  Volume: 73(8) Issue: 8 Pages: 2659-70
- DOI
  10.1158/0008-5472.can-12-3337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220014, KAKENHI-PROJECT-24390099, KAKENHI-PROJECT-24590419, KAKENHI-PROJECT-24590486
[Journal Article] Loss of membrane-bound serine protease inhibitor HAI-1 inducesoral squamous cell carcinoma cells' invasiveness2012
- Author(s)
  Baba T, Kawaguchi M, Fukushima T, Sato Y, Orikawa H, Yorita K, Tanaka H, Lin CY, Sakoda S, Kataoka H
- Journal Title
  
  J Pathol
  
  Volume: (Epub ahead of print) Issue: 2 Pages: 181-192
- DOI
  10.1002/path.3993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590375, KAKENHI-PROJECT-22790384, KAKENHI-PROJECT-23790250, KAKENHI-PROJECT-24390099, KAKENHI-PROJECT-24590419, KAKENHI-PROJECT-24590486
[Journal Article] Activation of macrophage-stimulating protein by human airway trypsin-like protease2012
- Author(s)
  Orikawa H, Kawaguchi M, Baba T, Yorita K, Sakoda S, Kataoka H
- Journal Title
  
  FEBS Lett
  
  Volume: 586 Pages: 217-221
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250
[Journal Article] Activation of macrophage-stimulating protein by human airway trypsin-like protease2012
- Author(s)
  Orikawa H, Kawaguchi M, Baba T, Yorita K, Sakoda S, Kataoka H
- Journal Title
  
  FEBS Letters
  
  Volume: 586 Issue: 3 Pages: 217-221
- DOI
  10.1016/j.febslet.2012.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390114, KAKENHI-PROJECT-23790250
[Journal Article] Loss of membrane-bound serine protease inhibitor HAI-1 induces oral squamous cell carcinoma cells invasiveness2012
- Author(s)
  Baba T, Kawaguchi M, Fukushima T, Sato Y, Orikawa H,Yorita K,Tanaka H,Lin C-Y, Sakoda S, Kataoka H
- Journal Title
  
  J. Pathol
  
  Volume: 228 Pages: 181-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250
[Journal Article] Antitumor effect of dehydroxymethylepoxyquinomicin (DHMEQ),a small molecule inhibitor of nuclear factor-kB, on glioblastoma.2012
- Author(s)
  Fukushima T, Kawaguchi M, Yorita K, Tanaka H, Umezawa K, Takeshima H, Kataoka H
- Journal Title
  
  Neuro. Oncol
  
  Volume: 14 Pages: 19-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250
[Journal Article] Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity2011
- Author(s)
  Kawaguchi M, Takeda N, Hoshiko S, Yorita K, Baba T, Sawaguchi A, Nezu Y, Yoshikawa T, Fukushima T, Kataoka H
- Journal Title
  
  American Journal of Pathology
  
  Volume: 179 Issue: 4 Pages: 1815-1826
- DOI
  10.1016/j.ajpath.2011.06.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390114, KAKENHI-PROJECT-22790384, KAKENHI-PROJECT-23790250
[Journal Article] Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity2011
- Author(s)
  Kawaguchi M, Takeda N, Hoshiko S, Yorita K, Baba T, Sawaguchi A, Nezu Y, Yoshikawa T, Fukushima T, Kataoka H
- Journal Title
  
  Am. J. Pathol
  
  Volume: 179 Pages: 1815-1826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790250
[Journal Article] Hepatocyte growth factor activator inhibitor type 1 suppresses metastatic pulmonary colonization of pancreatic carcinoma cells2011
- Author(s)
  Fukushima T, Kawaguchi M, Yamasaki M, Tanaka H, Yorita K, Kataoka H
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Issue: 2 Pages: 407-413
- DOI
  10.1111/j.1349-7006.2010.01808.x
- NAID
  10029290246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590375, KAKENHI-PROJECT-22790384, KAKENHI-PROJECT-23790250
[Presentation] Loss of matriptase leads to colorectal carcinogenesis and causes abnormal localization of Claudin-7 in tumor cells.2022
- Author(s)
  Kawaguchi M, Kiwaki T, Fukushima T, Kataoka H
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07154
[Presentation] HAI-2 (SPINT2 ) はEpCAM/Claudin-7複合体を安定化し、腸上皮完全性を維持する2020
- Author(s)
  川口真紀子、山本晃士、山下文希、福島剛、片岡寛章
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] HAI-2欠損マウスは腸管上皮の破綻を来たし早期に致死となる2019
- Author(s)
  川口真紀子、山本晃士、山下文希、福島剛、片岡寛章
- Organizer
  第24回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] Protease-activated receptor 2 promotes intestinal tumorigenesis through activation of NF-κB signaling and tumor angiogenesis in ApcMin/+mice2019
- Author(s)
  Kawaguchi M, Yamamoto K, Kiwaki T, FukushimaT, Camerer E, Kataoka H
- Organizer
  ASBMB Special Symposia Series; Serine Proteases in Pericellular Proteolysis and Signaling
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] HAI-1 deficient ApcMin+mice increased tumor formation through promoting tumor angiogenesis by PAR-2 signaling2019
- Author(s)
  Kawaguchi M, Yamamoto K, FukushimaT, Kataoka H
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] Concomitant deletion of PAR-2 abrogated the increased tumor formation in HAI-1 deficient ApcMin+ mice2018
- Author(s)
  Kawaguchi M, Yamamoto K, Fukushima T, Kataoka H
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] HAI-1欠損によるDSS誘発大腸炎の感受性亢進と腸粘膜上皮の修復再生過程におけるPAR-2活性化の意義に関する研究2018
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] HAIによる標的プロテアーゼ活性調節を介した上皮完全性の制御2018
- Author(s)
  川口真紀子、山本晃士、田中弘之、福島剛、片岡寛章
- Organizer
  第23回日本病態プロテアーゼ学会
- Data Source
  KAKENHI-PROJECT-18K06964
[Presentation] Accelerated tumor formation induced by Hai-1 deficiency in the ApcMin/+ model is prevented by concomitant deficiency of Par-22017
- Author(s)
  Kawaguchi M, Yamamoto K, FukushimaT, Camerer E, Kataoka H
- Organizer
  ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] HAI-1欠損はPAR-2シグナル活性化を介して腸管発癌を亢進させる2017
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第22回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] HAI-1 は proteasxe activated receptor-2 (PAR-2) を介して表皮及び毛髪の形態形成を維持する2017
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] 表皮及び毛髪の形態形成の諸段階におけるHAI-1発現の意義に関する検討2017
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] Excess activation of PAR-2 increased frequency of tumor formation in HAI-1 deficient ApcMin+ mice2017
- Author(s)
  Kawaguchi M, Yamamoto K, Fukushima T, Kataoka H
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] PAR-2活性化は軽度のDSS誘発大腸炎におけるHAI-1欠損マウスの感受性亢進に関与する2016
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] Loss of HAI-1 upregulates MMP-9 expression and induces degradation of epidermal basement membrane2016
- Author(s)
  Kawaguchi M, Fukushima T, Kataoka H
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] HAI-1欠損はnuclear factor-κB経路の活性化を介して腸管発癌を亢進させる2016
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第34回日本ヒト細胞学会学術集会
- Place of Presentation
  奈良市
- Year and Date
  2016-07-16
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] HAI-1欠損はPAR-2活性化を介して炎症に対する感受性を亢進させる2016
- Author(s)
  川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第21回日本病態プロテアーゼ学会
- Place of Presentation
  豊中市
- Year and Date
  2016-08-05
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] 癌細胞におけるHAI-1発現の減弱は腫瘍随伴線維芽細胞の遊走を惹起する2015
- Author(s)
  金丸愛、川口真紀子、山本晃士、福島剛、片岡寛章
- Organizer
  第33回日本ヒト細胞学会学術集会
- Place of Presentation
  ホテルスカイタワー（宮崎県・宮崎市）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] HGF activator inhibitors (HAIs) may have fundamental roles in biology of colon adenocarcinoma cells2015
- Author(s)
  Kawaguchi M, Fukushima T, Kataoka H
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] Protease-activated receptor-2 is not involved in the susceptibility to DSS-induced colitis associated with HAI-1deficiency2015
- Author(s)
  Kawaguchi M, Kanemaru A, Yamamoto K, Fukushima T, Camerer E, Kataoka H
- Organizer
  ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases
- Place of Presentation
  Potomac, MD, USA
- Year and Date
  2015-09-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] 口腔扁平上皮癌におけるHepatocyte growth factor activator inhibitor type-2(HAI-2)の発現と意義2015
- Author(s)
  山本晃士、上條苑子、小成一臣、川口真紀子、福島剛、金丸愛、馬場貴、山下義弘、片岡寛章
- Organizer
  第33回日本ヒト細胞学会学術集会
- Place of Presentation
  ホテルスカイタワー（宮崎県・宮崎市）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] Protease-activated receptor-2 is not involved in the susceptibility to DSS-induced colitis associated with HAI-1deficiency.2015
- Author(s)
  Kawaguchi M, Kanemaru A, Yamamoto K, Fukushima T, Camerer E, Kataoka H.
- Organizer
  ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases
- Place of Presentation
  Potomac, MD, USA
- Year and Date
  2015-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 癌随伴線維芽細胞の遊走における癌細胞周囲微小環境トリプシン様セリンプロテアーゼ活性の意義2015
- Author(s)
  片岡寛章、金丸　愛、川口真紀子、山本晃士、福島　剛
- Organizer
  第104回日本病理学会総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-05-01
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] HAI-1による標的プロテアーゼ活性調節を介したがん悪性形質の制御2015
- Author(s)
  川口真紀子、福島剛、金丸愛、山本晃士、田中弘之、片岡寛章
- Organizer
  第33回日本ヒト細胞学会学術集会
- Place of Presentation
  宮崎市
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-15K08311
[Presentation] 膠芽腫における HAI-2 遺伝子の DNA メチル化状態2015
- Author(s)
  福島剛、藤田聡、川口真紀子、金丸愛、山本晃士、田中弘之、片岡寛章
- Organizer
  第33回日本ヒト細胞学会学術集会
- Place of Presentation
  ホテルスカイタワー（宮崎県・宮崎市）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] The insufficient pericellular activity of hepatocyte growth factor activator inhibitor type 1 (HAI-1) induces recruitment of cancer-associated fibroblasts.2015
- Author(s)
  Kanemaru A, Yamamoto K, Kawaguchi M, Camerer E, Kataoka H.
- Organizer
  ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases
- Place of Presentation
  Potomac, MD, USA
- Year and Date
  2015-09-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for maintaining keratinocyte morphology through regulation of PAR-2-dependent p38 MAP kinase signaling2013
- Author(s)
  Makiko Kawaguchi, Naoki Takeda, Ai Kanemaru, Akira Sawaguchi, Tsuyoshi Fukushima, Hiroaki Kataoka
- Organizer
  ASBMB Special Symposia Series; Membrane-Anchored Serine Proteases
- Place of Presentation
  Potomac, MD, USA
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] 腸管発癌におけるHepatocyte growth factor activator inhibitor type1 (HAI-1) の意義2013
- Author(s)
  川口真紀子，星子新理，金丸愛，梅澤一夫，片岡寛章
- Organizer
  第10回日本病理学会カンファレンス
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] Ye JJ, Kawaguchi M, Haruyama Y, Kanemaru A, Fukushima T, Kataoka H2013
- Author(s)
  Ye JJ, Kawaguchi M, Haruyama Y, Kanemaru A, Fukushima T, Kataoka H
- Organizer
  An AACR Special Conference on Tumor Invasion and Metastasis.
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2013-01-21
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) suppresses tumor growth and metastasis of pancreatic adenocarcinoma cells.2013
- Author(s)
  Ye J-J, Kawaguchi M, HaruyamaY, Ai Kanemaru A, Fukushima T, Kataoka H
- Organizer
  AACR Special Conference of Tumor Invasion andMetastasis
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2013-01-21
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 表皮ケラチノサイトにおける細胞膜結合型セリンプロテアーゼ活性制御の意義2013
- Author(s)
  川口真紀子、金丸愛、山本晃士、片岡寛章
- Organizer
  第18回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  大阪府豊中市
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) suppresses tumor growth and metastasis of pancreatic adenocarcinoma cells.2013
- Author(s)
  Jing-Jia Ye, Makiko Kawaguchi, Yukihiro Haruyama, Ai Kanemaru,Tsuyoshi Fukushima, Hiroaki Kataoka
- Organizer
  An AACR Special Conference on Tumor Invasion and Metastasis
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] HGF activator inhibitor type 1 (HAI-1) suppresses tumor growth and metastasis of pancreatic adenocarcinoma cells2012
- Author(s)
  Kawaguchi M, Haruyama Y, Kataoka H
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] 膜型プロテアーゼインヒビターHAI-1 による口腔扁平上皮癌の浸潤制御2012
- Author(s)
  片岡寛章、馬場貴、福島剛、川口真紀子、迫田隅男
- Organizer
  第21回日本がん転移学会学術集会
- Place of Presentation
  広島
- Year and Date
  2012-07-21
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] HGF activator inhibitor type 1 (HAI-l) suppresses tumor growth and metastasis of pancreatic adenocarcinoma cells.2012
- Author(s)
  Kawaguchi M, Haruyama Y, Kataoka H
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 細胞膜結合型プロテアーゼインヒビターHAI-1は表皮角化細胞の形態形成に必須である.2012
- Author(s)
  川口真紀子、竹田直樹、星子新理、福島剛、片岡寛章
- Organizer
  第17回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松市
- Year and Date
  2012-08-17
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 膜型プロテアーゼインヒビターHAT-1による口腔扁平上皮癌の浸潤制御,膜型プロテアーゼインヒビターHAI-1による口腔扁平上皮癌の臍潤制御.2012
- Author(s)
  片岡寛章、馬場貴、福島剛、川口真紀子、迫田隅男
- Organizer
  第21回日本がん転移学会学術集会
- Place of Presentation
  広島市
- Year and Date
  2012-07-12
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 細胞膜結合型プロテアーゼインヒビター HAI-1 は表皮角化細胞の形態形成に必須である2012
- Author(s)
  川口真紀子、竹田直樹、星子新理、福島剛、片岡寛章
- Organizer
  第17回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松市
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] 細胞膜結合型プロテアーゼインヒビターHAI-1 は表皮角化細胞の形態形成に必須である2012
- Author(s)
  川口真紀子、竹田直樹、星子新理、福島剛、片岡寛章
- Organizer
  第17回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  浜松
- Year and Date
  2012-08-17
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] 口腔扁平上皮癌におけるHepatocyte growth factor activator inhibitor type1 (HAI-1)の発現と意義2012
- Author(s)
  馬場貴、川口真紀子、頼田顕辞、福島剛、迫田隅男、片岡寛章
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-26
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] HGF activator inhibitor type 1 (HAI-1) suppresses tumor growth and metastasis of pancreatic adenocarcinoma cells.2012
- Author(s)
  Makiko Kawaguchi, Yukihiro Haruyama, Hiroaki Kataoka
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] 細胞膜結合型セリンプロテアーゼインヒビターHepatocyte growth factor activator inhibitor type 1 (HAI-1) は腸上皮完全性維持に必須である2011
- Author(s)
  川口真紀子、竹田直樹、星子新理、頼田顕辞、馬場貴、澤口朗、福島剛、片岡寛章
- Organizer
  第16回日本病態プロテアーゼ学会学術総会
- Place of Presentation
  豊中
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Type II membrane-type serine protease, matriptase, is expressed in perivascular tumor cells HLC-1 xenograft2011
- Author(s)
  Kawaguchi M, Baba T, Fukushi ma T, Kataoka H
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Hepatpcyte growth factoractivator inhibitor type 1 (HAI-1) regulates cell morphology through control of the actin cytoskeleton in epidermal keratinocyte2011
- Author(s)
  Kawaguchi M, Takeda N, Sawaguchi A, Sato Y, Hoshiko S, Fukushima T, Kataoka H
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) plays an important role in maintaining integrity of intestinal epithelium.2011
- Author(s)
  Kawaguchi M, Hoshiko S, Yorita K, Baba T, Fukushima T, Kataoka H
- Organizer
  XlIIth International Workshop on Molecular & Cellular Biology of Plasminogen Activation
- Place of Presentation
  Clare College, Cambridge, UK
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) は表皮角化細胞の形態形成を制御している2011
- Author(s)
  川口真紀子、星子新理、福島剛、田中弘之、頼田顕辞、梅北佳子、片岡寛章
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-04-29
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Defect of hepatocyte growth factor activator inhibitor type1, a cell surface serine protease inhibitor2011
- Author(s)
  Hoshiko S, Kawaguchi M, Yorita K, Fukushima T, Kataoka H
- Organizer
  enhances intestinal tumorigenesis in ApcMin/+ mice
- Place of Presentation
  Chicago, USA
- Year and Date
  2011-05-10
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] 細胞膜結合型セリンプロテアーゼインヒビター、Hepatocyte growth factor activator inhibitor type 1 (HAI-1) は腸上皮完全性維持に必須である2011
- Author(s)
  川口真紀子、竹田直樹、星子新理、頼田顕辞、馬場貴、澤口朗、福島剛、片岡寛章
- Organizer
  第16回日本病態プロテアーゼ学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府）
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) plays an important role in maintaining integrity of intestinal epithelium2011
- Author(s)
  Kawaguchi M, Hoshiko S, Yorita K, Baba T, Fukushima T, Kataoka H
- Organizer
  XlIIth International Workshop on Molecular & Cellular Biology of Plasminogen Activation
- Place of Presentation
  Cambridge, UK
- Year and Date
  2011-07-10
- Data Source
  KAKENHI-PROJECT-23790250
[Presentation] Hepatocyte growth factor activator inhibitor type 1 suppresses invasion of pancreatic adenocarcinoma cells through inhibition of matriptase/protease-activated receptor-2 axis.
- Author(s)
  Haruyama Y, Ye J-J, Kawaguchi M, Kanemaru A, Fukushima T, Kataoka H
- Organizer
  The 105th Annual Meeting of American Association of Cancer Research
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 低分子NF-ｋB阻害剤DHMEQはHAI-1欠損による腸管発癌亢進を抑制する
- Author(s)
  川口真紀子、金丸愛、梅澤一夫、片岡寛章
- Organizer
  第19回日本病態プロテアーゼ学会
- Place of Presentation
  大阪府豊中市
- Year and Date
  2014-08-08 – 2014-08-09
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] HGF activator inhibitor-1 (HAI-1) による表皮細胞PAR-2活性化制御の意義
- Author(s)
  川口真紀子、金丸愛、山本晃士、福島剛、片岡寛章
- Organizer
  第33回分子病理学研究会
- Place of Presentation
  宮城県刈田郡
- Year and Date
  2014-07-25 – 2014-07-26
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] 腸管発癌におけるHepatocyte growth factor activator inhibitor type 1 (HAI-1)の意義．
- Author(s)
  川口真紀子、星子新理、金丸　愛、梅澤一夫、片岡寛章
- Organizer
  第10回病理学会カンファレンス
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] HAI-1 はマトリプテースによる PAR2 活性化制御を介してケラチノサイトの細胞間接着維持に働く．
- Author(s)
  片岡寛章、川口真紀子、金丸愛、福島剛
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島市
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] Roles for HAI-1, a cell surface inhibitor of membrane-anchored serine proteases, in epithelial integrity and cancer progression.
- Author(s)
  Kataoka H, Kawaguchi M.
- Organizer
  ASBMB Special Symposia Series: Membrane-Anchored Serine Proteases
- Place of Presentation
  Potomac MD, USAPotomac MD, USA
- Invited
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] 表皮ケラチノサイトにおける細胞膜結合型セリンプロテアーゼ活性制御の意義
- Author(s)
  川口真紀子、金丸愛、山本晃士、片岡寛章
- Organizer
  第18回日本病態プロテアーゼ学会
- Place of Presentation
  豊中市
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for maintaining keratinocyte morphology through regulation of PAR-2-dependent p38 MAP kinase signaling.
- Author(s)
  Kawaguchi M, Takeda N, Kanemaru A, Sawaguchi A, Fukushima T, Kataoka H.
- Organizer
  ASBMB Special Symposia Series: Membrane-Anchored Serine Proteases
- Place of Presentation
  Potomac MD, USAPotomac MD, USA
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] HAI-1 はマトリプテースによる PAR2 活性化制御を介してケラチノサイトの細胞間接着維持に働く
- Author(s)
  片岡寛章、川口真紀子、金丸愛、福島剛
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島市
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] Antitumor effect of DHMEQ, a small molecule inhibitor of nuclear factor-κ B, on Hai-1-deficient ApcMin+ mice.
- Author(s)
  Kawaguchi M, Haruyama Y, Umezawa K, Fukushima T, Kataoka H
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390099
[Presentation] Roles of HAI-1, a membrane-anchored serine protease inhibitor, in maintaining keratinocyte morphology
- Author(s)
  Kawaguchi M, Kanemaru A, Fukushima T, and Kataoka H
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] Antitumor effect of DHMEQ, a small molecule inhibitor of nuclear factor-κ B, on Hai-1-deficient ApcMin+ mice
- Author(s)
  Kawaguchi M, Haruyama Y, Umezawa K, Fukushima T, Kataoka H
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860166
[Presentation] Effect of CD24 silencing on pancreatic ductal cell adenocarcinoma cells.
- Author(s)
  Fukushima T, Haruyama Y, Kawaguchi M, Tanaka H, and Kataoka H
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24390099

1. KATAOKA HIROAKI (10214321)

# of Collaborated Projects: 1 results

# of Collaborated Products: 30 results
2. TAKEDA NAOKI (90304998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. ISHIDA YOICHI (90510454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. FUKUSHIMA TSUYOSHI (10452913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
5. Hishikawa Yoshitaka (60304276)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石塚匠 (50700085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. チョウジョウフナランツオツク (90640962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. ピューシンウー (90718123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANAKA Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 清木元治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawaguchi Makiko 川口 真紀子

川口 真紀子 カワグチ マキコ

KAWAGUCHI Makiko 川口 真紀子

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先天性ナトリウム下痢症の発症メカニズム解明と治療法の開発Principal Investigator

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大腸発癌におけるマトリプターゼ発現の意義に関する研究Principal Investigator

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Regulation of membrane-anchored serine protease activities and its significance in epithelial pathophysiologyPrincipal Investigator

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The analysis of microRNA localization using fluorescence resonance energy transfer based in situ hybridization

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Roles of HAI-1, a membrane-anchored serine protease inhibitor, in intestinal carcinogenesis through regulating pericellular proteolysisPrincipal Investigator

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Roles of HAI-1, a membrane-anchored serine protease inhibitor, in maintaining keratinocyte morphologyPrincipal Investigator

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Regulation of protease activities on the epithelial cell surface and its significance in epithelial disorders.

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Role of membrane-bound serine protease inhibitor in maintaining integrity of intestinal epitheliumPrincipal Investigator

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[Journal Article] Matriptase-2 regulates iron homeostasis primarily by setting the basal levels of hepatic hepcidin expression through a nonproteolytic mechanism2023

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[Journal Article] Early-onset tufting enteropathy in HAI-2-deficient mice is independent of matriptase-mediated cleavage of EpCAM2023

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[Journal Article] Protease‐activated receptor‐2 accelerates intestinal tumor formation through activation of nuclear factor‐κB signaling and tumor angiogenesis in Apc Min/+ mice2020

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[Journal Article] Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine2019

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[Journal Article] 腸上皮の正常性維持に不可欠な細胞膜結合セリンプロテアーゼ制御機構2019

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[Journal Article] Aberrant methylation and silencing of the SPINT2 gene in high-grade gliomas.2018

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Kawaguchi Makiko 川口真紀子

川口真紀子カワグチマキコ

KAWAGUCHI Makiko 川口真紀子