YAMAMOTO Yukiya 山本幸也

… Alternative Names

山本幸也ヤマモトユキヤ

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Researcher Number	90410703
Other IDs	https://orcid.org/0000-0002-7439-4925
Affiliation (Current)	2025: 中部大学, 生命健康科学部, 教授 2025: 藤田医科大学, 医学部, 客員准教授
Affiliation (based on the past Project Information) *help	2018 – 2019: 藤田医科大学, 医学部, 准教授 2017: 藤田保健衛生大学, 医学部, 准教授 2016: 藤田保健衛生大学, 医学部, 講師 2011 – 2014: 藤田保健衛生大学, 医学部, 講師 2006 – 2007: 藤田保健衛生大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Hematology Except Principal Investigator Hematology
Keywords	Principal Investigator 急性骨髄性白血病 / がん抑制因子 / 急性骨髄球性白血病 / 急性前骨髄球性白血病 / 転写因子 / 急性骨髄性白血 / 急性前骨髄性白血 / 遺伝子異常 / RARA / BCOR / 急性前骨髄性白血病 / ファージライブラリー / 抗体療法 … More Except Principal Investigator … More ゲノム / 遺伝子 / 癌 / 染色体転座 / 白血病 / 複雑核型 / 融合遺伝子 / 造血器腫瘍 / EMID1 / ARID1B / MAML3 / TCF4 / G-CSF / RUNX1 / Leukemia / translocation / fusion gene / RNA-seq Less

Identification and functional analysis of gene aberrations in hematological malignancy with complex chromosomal abnormality using RNA-seq analysis
- Principal Investigator
  
  ABE AKIHIRO
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University
Leukemogenic property of acute promyelocytic leukemia gene, BCOR-RARAPrincipal Investigator
- Principal Investigator
  
  YAMAMOTO Yukiya
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University
急性骨髄性白血病抗原に対する網羅的探索と新規抗体療法開発のための基礎的研究Principal Investigator
- Principal Investigator
  
  山本幸也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Fujita Health University

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Truncated RUNX1 generated from the　fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances　sensitivity　to granulocyte colony-stimulating factor2020
- Author(s)
  Abe A, Yamamoto Y, Katsumi A, Yamamoto H, Okamoto A, Inaguma Y, Iriyama C, Tokuda M, Okamoto M, Emi N, Tomita A.
- Journal Title
  
  Cytogenetic and Genome Research
  
  Volume: - Issue: 5 Pages: 255-263
- DOI
  10.1159/000508012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09860, KAKENHI-PROJECT-19K08853, KAKENHI-PROJECT-18K15402
[Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017
- Author(s)
  Abe A, Yamamoto Y, Katsumi A, Okamoto A, Tokuda M, Inaguma Y, Yamamoto K, Yanada M, Kanie T, Tomita A, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Int J Hematol.
  
  Volume: - Issue: 2 Pages: 208-212
- DOI
  10.1007/s12185-017-2387-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09451, KAKENHI-PROJECT-15K09473, KAKENHI-PROJECT-17K07182, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-16K09860
[Journal Article] ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.2016
- Author(s)
  Abe A, Yamamoto Y, Iba S, Kanie T, Okamoto A, Tokuda M, Inaguma Y, Yanada M, Morishima S, Mizuta S, Akatsuka Y, Okamoto M, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  Genes, chromosomes & cancer
  
  Volume: 55(3) Issue: 3 Pages: 242-250
- DOI
  10.1002/gcc.22327
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13).2016
- Author(s)
  Abe A, Mizuta S, Okamoto A, Yamamoto Y, Kameyama T, Mayeda A, Emi N.
- Journal Title
  
  International journal of laboratory hematology
  
  Volume: 38(2) Issue: 2 Pages: 15-18
- DOI
  10.1111/ijlh.12450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430124, KAKENHI-PROJECT-26460259, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25640081, KAKENHI-PROJECT-24310161, KAKENHI-PROJECT-16K09860
[Journal Article] The fate of patients with acute myeloid leukemia not undergoing induction chemotherapy.2015
- Author(s)
  Masamitsu Yanada, Akinao Okamoto, Yoko Inaguma, Masutaka Tokuda, Satoko Morishima, Tadaharu Kanie, Yukiya Yamamoto, Shuichi Mizuta, Yoshiki Akatsuka, Masataka Okamoto, Nobuhiko Emi.
- Journal Title
  
  International journal of hematology.
  
  Volume: Published online Issue: 1 Pages: 35-40
- DOI
  10.1007/s12185-015-1786-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410
[Journal Article] Construction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H.2014
- Author(s)
  Inaguma Y, Akahori Y, Murayama Y, Shiraishi K, Tsuzuki-Iba S, Endoh A, Tsujikawa J, Demachi-Okamura A, Hiramatsu K, Saji H, Yamamoto Y, Yamamoto N, Nishimura Y, Takahashi T, Kuzushima K, Emi N, Akatsuka Y
- Journal Title
  
  Gene Therapy
  
  Volume: 21 Pages: 575-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410
[Journal Article] A varicella outbreak in B-cell lymphoma patients receiving rituximab-containing chemotherapy2014
- Author(s)
  Akinao Okamoto, Akihiro Abe, Masataka Okamoto, Tsukane Kobayashi, Yoko Inaguma, Masutaka Tokuda, Masamitsu Yanada, Satoko Morishima, Tadaharu Kanie, Yukiya Yamamoto, Motohiro Tsuzuki, Shuichi Mizuta, Yoshiki Akatsuka, Hiroshi Yatsuya, Tetsushi Yoshikawa, Nobuhiko Emi.
- Journal Title
  
  J Infect Chemother.
  
  Volume: 20 Pages: 774-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410
[Journal Article] Clarifying the Impact of Polycomb Complex Component Disruption in Human Cancers.2014
- Author(s)
  Yamamoto Y, Abe A, Emi N
- Journal Title
  
  Molecular Cancer Research
  
  Volume: 12 Issue: 4 Pages: 479-84
- DOI
  10.1158/1541-7786.mcr-13-0596
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591410, KAKENHI-PROJECT-25461437
[Journal Article] Functionally Deregulated AML1/RUNX1 Cooperates with BCR-ABL to Induce a Blastic Phase-Like Phenotype of Chronic Myelogenous Leukemia in Mice.2013
- Author(s)
  Kiyoko Yamamoto, Shinobu Tsuzuki, Yosuke Minami, Yukiya Yamamoto, Akihiro Abe, Koichi Ohshima, Masao Seto, Tomoki Naoe.
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 9 Pages: e74864-e74864
- DOI
  10.1371/journal.pone.0074864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410, KAKENHI-PROJECT-24390249, KAKENHI-PROJECT-25461412, KAKENHI-PROJECT-25461437, KAKENHI-PROJECT-25670449
[Journal Article] t(X;17)(p11;q21) BCOR/RARA2012
- Author(s)
  Yukiya Yamamoto
- Journal Title
  
  Atlas Genet Cytogenet Oncol Haematol
  
  Volume: January 2012
- URL
  http://AtlasGeneticsOncology.org/Anomalies/t0X17p11q21ID1594.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410
[Journal Article] Isolation of human mAbs that directly modulate FMS-related tyrosine kinase 3 signaling2012
- Author(s)
  Yukiya Yamamoto
- Journal Title
  
  Cancer Science
  
  Volume: 103(2) Pages: 350-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410
[Journal Article] A novel RUNX1-C11orf41 fusion gene in a case of acute myeloid leukemia with t(11;21)(p14;q22).2012
- Author(s)
  Abe A, Katsumi A, Kobayashi M, Okamoto A, Tokuda M, Kanie T, Yamamoto Y, Naoe T, Emi N.
- Journal Title
  
  Cancer Genetics
  
  Volume: 205(11) Issue: 11 Pages: 608-11
- DOI
  10.1016/j.cancergen.2012.10.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591410, KAKENHI-PROJECT-24591416
[Presentation] TCF4-MAML3融合遺伝子を認めたCD4+CD56+芽球性NK細胞白血病の１例2019
- Author(s)
  安部明弘、山本幸也、山本秀行、徳田倍将、稲熊容子、岡本晃直、入山智沙子、冨田章裕、岡本昌隆、恵美宣彦
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] ETV6の再構成による異所性遺伝子発現を認めた急性骨髄性白血病の二症例2018
- Author(s)
  安部明弘、山本幸也、岡本晃直、入山智沙子、徳田倍将、稲熊容子、蟹江匡治、冨田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田　明、恵美宣彦
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] 再発急性骨髄性白血病において微小転座から複数のスプライシング産物を認めたRUNX1-GRIK2融合遺伝子2017
- Author(s)
  安部明弘、山本幸也、岡本晃直、徳田倍将、稲熊容子、柳田正光、蟹江匡治、冨田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田明、恵美宣彦
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] ETV6転座によるPDGFRαとGSX2の高発現を認めたt(4;12)を有するAMLの一例2016
- Author(s)
  安部明弘、水田秀一、山本幸也、岡本晃直、伊庭佐知子、徳田倍将、稲熊容子、柳田正光、森島聡子、蟹江匡治、富田章裕、赤塚美樹、岡本昌隆、亀山俊樹、前田明、恵美宣彦
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09860
[Presentation] Clarifying the Impact of Polycomb Complex Component Disruption in Human Cancers2014
- Author(s)
  Yamamoto Y, Abe A, Emi N
- Organizer
  American Association of Cancer Research Annual Meeting 2014
- Place of Presentation
  San Diego Convention Center; San Diego, CA, USA
- Year and Date
  2014-04-06
- Data Source
  KAKENHI-PROJECT-23591410
[Presentation] BCOR as a novel fusion partner of retinoic acid receptor alpha in a t(X;17)(p11;q12) variant of acute promyelocytic leukemia2011
- Author(s)
  山本幸也
- Organizer
  第８回基礎血液懇話会(招待講演)
- Place of Presentation
  名古屋大学医学部
- Data Source
  KAKENHI-PROJECT-23591410
[Presentation] Isolation of human monoclonal antibodies with antagonistic activity for FLT3 targeting therapy2011
- Author(s)
  Yukiya Yamamoto
- Organizer
  第７３回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23591410
[Presentation] t(X;17)(p11;q12)急性前骨髄性白血病における融合遺伝子 BCOR-RARAのクローニングと機能解析2011
- Author(s)
  山本幸也
- Organizer
  第7回麒麟塾(招待講演)
- Place of Presentation
  コクヨホール　東京都港区港南
- Data Source
  KAKENHI-PROJECT-23591410

1. ABE AKIHIRO (00432261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. 恵美宣彦 (30185144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. KATSUMI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 亀山俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

YAMAMOTO Yukiya 山本 幸也

山本 幸也 ヤマモト ユキヤ

Research Projects

Research Products

Co-Researchers

Identification and functional analysis of gene aberrations in hematological malignancy with complex chromosomal abnormality using RNA-seq analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Leukemogenic property of acute promyelocytic leukemia gene, BCOR-RARAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

急性骨髄性白血病抗原に対する網羅的探索と新規抗体療法開発のための基礎的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Truncated RUNX1 generated from the fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances sensitivity to granulocyte colony-stimulating factor2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rearrangement of VPS13B, a causative gene of Cohen syndrome, in a case of RUNX1-RUNX1T1 leukemia with t(8;12;21).2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ETV6-LPXN fusion transcript generated by t(11;12)(q12.1;p13) in a patient with relapsing acute myeloid leukemia with NUP98-HOXA9.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transcriptional activation of platelet-derived growth factor receptor α and GS homeobox 2 resulting from E26 transformation-specific variant 6 translocation in a case of acute myeloid leukemia with t(4;12)(q12;p13).2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The fate of patients with acute myeloid leukemia not undergoing induction chemotherapy.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction and molecular characterization of a T-cell receptor-like antibody and CAR-T cells specific for minor histocompatibility antigen HA-1H.2014

Author(s)

Journal Title

Data Source

[Journal Article] A varicella outbreak in B-cell lymphoma patients receiving rituximab-containing chemotherapy2014

Author(s)

Journal Title

Data Source

[Journal Article] Clarifying the Impact of Polycomb Complex Component Disruption in Human Cancers.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Functionally Deregulated AML1/RUNX1 Cooperates with BCR-ABL to Induce a Blastic Phase-Like Phenotype of Chronic Myelogenous Leukemia in Mice.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] t(X;17)(p11;q21) BCOR/RARA2012

Author(s)

Journal Title

URL

Data Source

[Journal Article] Isolation of human mAbs that directly modulate FMS-related tyrosine kinase 3 signaling2012

Author(s)

Journal Title

Data Source

[Journal Article] A novel RUNX1-C11orf41 fusion gene in a case of acute myeloid leukemia with t(11;21)(p14;q22).2012

Author(s)

Journal Title

DOI

Data Source

YAMAMOTO Yukiya 山本幸也

山本幸也ヤマモトユキヤ

[Journal Article] Truncated RUNX1 generated from the　fusion of RUNX1 to antisense GRIK2 via a cryptic chromosome translocation enhances　sensitivity　to granulocyte colony-stimulating factor2020