TAKATORI Yuki 高鳥悠記

… Alternative Names

高鳥悠記タカトリユキ

Takada-Takatori Yuki 高鳥悠記

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Researcher Number	90411090
Other IDs
Affiliation (Current)	2025: 武庫川女子大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 同志社女子大学, 薬学部, 助教 2017 – 2019: 同志社女子大学, 薬学部, 助教 2007 – 2014: Doshisha Women's College of Liberal Arts, Faculty of Pharmaceutical Sciences, Research Associate 2006: 同志社女子大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Pharmacology in pharmacy / Basic Section 47040:Pharmacology-related / Biological pharmacy Except Principal Investigator Biological pharmacy / General pharmacology
Keywords	Principal Investigator アルツハイマー病 / 薬理学 / アルツハイマー / ニコチン受容体 / 脳・神経 / 薬学 / タウ / アルツハイマー型認知症 / 神経保護作用 / ニューロン … More / 神経保護 / 認知症 / 細胞・組織 / 神経科学 … More Except Principal Investigator アセチルコリン / Acetylcholine / nicotinic receptor / ニコチン受容体 / ムスカリン受容体 / コリンアセチルトランスフェラーゼ / リンパ球 / Receptor / Bioactive molecule / Brain and Neuron / Neuroscience / Pharmaceutical Sciences / Pharmacology / ムスカリン受容体の弛緩機構 / 膜胱括約筋 / 受容体 / 生体分子 / 脳・神経 / 神経科学 / 薬学 / 薬理学 / ラジオイムノアッセイ / phytohemagglutinin / mediatophore / T cell / vacuolar ATPase / Ｔリンパ球 / メディエートフォア / 液胞型プロトンポンプ / Ｂリンパ球 / Tリンパ球 / obesity / choline acetyltransferase / Lymphocyte / muscarinic receptor / acetylcholine / 肥満 Less

アルツハイマー病の治療・予防薬開発に向けた新規創薬ターゲットの探索Principal Investigator
- Principal Investigator
  
  高鳥悠記
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Doshisha Women's College of Liberal Arts
Development of novel therapeutic agents for Alzheimer's disease based on analysis of neuroprotective signals and regulation of tau phosphorylationPrincipal Investigator
- Principal Investigator
  
  Takada-Takatori Yuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
A novel mechanism through regulation of tau phosphorylation and neuroprotective effect by drugs for the treatment of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  TAKADA-TAKATORI YUKI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Interaction between vacuolar H+ ATPase and lymphocytic cholinergic system in regulation of immune function
- Principal Investigator
  
  FUJII Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Role of lymphocytic cholinergic system in regulation of fat metabolism
- Principal Investigator
  
  FUJII Takeshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
アルツハイマー病治療薬の新規神経保護作用機序に関する研究Principal Investigator
- Principal Investigator
  
  高鳥悠記
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Biological pharmacy
- Research Institution
  Doshisha Women's College of Liberal Arts
Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.
- Principal Investigator
  
  FUJII Takeshi, MATSUI Minoru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Doshisha Women's College of Liberal Arts
  The University of Tokyo

All 2019 2018 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] Nicotinic acetylcholine receptor signaling in neuroprotection2018
- Author(s)
  Toshiaki Kume and Yuki Takada-Takatori
- Total Pages
  192
- Publisher
  Springer
- ISBN
  9789811084874
- Data Source
  KAKENHI-PROJECT-17K08323
[Journal Article] Potential protective effect of highly bioavailable curcumin on an oxidative stress model induced by microinjection of sodium nitroprusside in mice brain.2014
- Author(s)
  Nazari, QA., Takada-Takatori, Y., Hashimoto, T., Imaizumi, A., Izumi, Y., Akaike, A., Kume, T.
- Journal Title
  
  Food Funct.
  
  Volume: 5 Issue: 5 Pages: 984-989
- DOI
  10.1039/c4fo00009a
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390139, KAKENHI-PROJECT-24590111, KAKENHI-PROJECT-25460095, KAKENHI-PROJECT-25670036, KAKENHI-PROJECT-25860069
[Journal Article] Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death2014
- Author(s)
  Yasuhiko Izumi, Masayuki Ezumi, Yuki Takada-Takatori, Akinori Akaike, and Toshiaki Kume
- Journal Title
  
  Toxicological Sciences
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860069
[Journal Article] Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death.2014
- Author(s)
  Izumi, Y., Ezumi, M., Takada-Takatori, Y., Akaike, A., and Kume, T.
- Journal Title
  
  Toxicol Sci.
  
  Volume: 139 Issue: 2 Pages: 466-478
- DOI
  10.1093/toxsci/kfu054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390139, KAKENHI-PROJECT-24590111, KAKENHI-PROJECT-25460095, KAKENHI-PROJECT-25670036, KAKENHI-PROJECT-25860069
[Journal Article] Staurosporine induces dopaminergic neurite outgrowth through AMP-activated protein kinase/mammalian target of rapamycin signaling pathway.2013
- Author(s)
  Wakita S, Izumi Y, Nakai T, Adachi K, Takada-Takatori Y, Kume T, Akaike A.
- Journal Title
  
  Neuropharmacology.
  
  Volume: 77C Pages: 39-48
- DOI
  10.1016/j.neuropharm.2013.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860069
[Journal Article] Protective Effect of Luteolin on an Oxidative-Stress Model Induced by Microinjection of Sodium Nitroprusside in Mice2013
- Author(s)
  Nazari, QA., Kume, T., Takada-Takatori, Y., Izumi, Y., and Akaike, A.
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 122 Issue: 2 Pages: 109-117
- DOI
  10.1254/jphs.13019FP
- NAID
  10031185403
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390139, KAKENHI-PROJECT-24590111, KAKENHI-PROJECT-25460095, KAKENHI-PROJECT-25670036, KAKENHI-PROJECT-25860069
[Journal Article] Neuroprotective Effects of Curcumin and Highly Bioavailable Curcumin on Oxidative Stress Induced by Sodium Nitroprusside in Rat Striatal Cell Culture2013
- Author(s)
  Nazari, QA., Kume, T., Izuo, N., Takada-Takatori, Y., Imaizumi, A., Hashimoto, T., Izumi, Y., and Akaike, A.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 8 Pages: 1356-1362
- DOI
  10.1248/bpb.b13-00300
- NAID
  130003361498
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390139, KAKENHI-PROJECT-24590111, KAKENHI-PROJECT-25460095, KAKENHI-PROJECT-25670036, KAKENHI-PROJECT-25860069
[Journal Article] Protective effect of serofendic acid, administered intravenously, on cerebral ischemia-reperfusion injury in rats.2013
- Author(s)
  Ioroi, T., Taguchi, K., Izumi, Y., Takada-Takatori, Y., Akaike, A., and Kume, T.
- Journal Title
  
  Brain Res.
  
  Volume: 1532 Pages: 99-105
- DOI
  10.1016/j.brainres.2013.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390139, KAKENHI-PROJECT-24590111, KAKENHI-PROJECT-25460095, KAKENHI-PROJECT-25670036, KAKENHI-PROJECT-25860069
[Journal Article] Regulatory mechanisms of acetylcholine synthesis and release by T cells2012
- Author(s)
  Fujii T, Takada-Takatori Y, Kawashima K
- Journal Title
  
  Life Sciences
  
  Volume: 91 Issue: 21-22 Pages: 981-985
- DOI
  10.1016/j.lfs.2012.04.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590121
[Journal Article] Mediatophore regulates acetylcholine release from T cells2012
- Author(s)
  Fujii T, Takada-Takatori Y, Horiguchi K, Kawashima K
- Journal Title
  
  Journal of Neuroimmunology
  
  Volume: 244 Issue: 1-2 Pages: 16-22
- DOI
  10.1016/j.jneuroim.2011.12.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590121
[Journal Article] 免疫機能とムスカリン受容体2011
- Author(s)
  藤井健志、高鳥悠記
- Journal Title
  
  鼻アレルギーフロンティア 11
  
  Pages: 36-41
- Data Source
  KAKENHI-PROJECT-20590096
[Journal Article] Acetylcholine synthesis and release in NIH3T3 cells co-expressing the high-affinity choline transporter and choline acetyltransferasae.2009
- Author(s)
  Fujii T, Masai M, Misawa H, Okuda T, Takada-Takatori Y, Moriwaki Y, Haga T, Kawashima K.
- Journal Title
  
  Journal of Neuroscience Research. 87
  
  Pages: 3024-3032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590096
[Journal Article] Effects of donepezil pretreatment against glutamate-induced neurotoxicity in rat cortical neuron chronically treated with donepezil.2008
- Author(s)
  Takada-Takatori, Yuki
- Journal Title
  
  Journal of Pharmacological Sciences 106
  
  Pages: 52-52
- Data Source
  KAKENHI-PROJECT-18890220
[Journal Article] Mechanisms of the nicotinic receptor up-regulation induced by chronic treatment with donepezil and sensitization to donepezl-induced neuroprotection2007
- Author(s)
  Takada-Takatori, Yuki
- Journal Title
  
  Journal of Pharmacological Sciences 103・Suppl1
  
  Pages: 59-59
- Data Source
  KAKENHI-PROJECT-18890220
[Journal Article] Effects of chronic treatment with donepezi lvia α7-nicotinic recepto rand phosphatidylinositol 3-kinase cascade.2007
- Author(s)
  Takada-Takatori, Yuki
- Journal Title
  
  Neuroscience Research 58
  
  Pages: 117-117
- Data Source
  KAKENHI-PROJECT-18890220
[Journal Article] Neroprotective effects of galanthamine and tacrine against glutamate neurotoxicity2006
- Author(s)
  Takada-Takatori, Yuki
- Journal Title
  
  European Journal of Pharmacology 549
  
  Pages: 19-26
- Data Source
  KAKENHI-PROJECT-18890220
[Journal Article] Mechanisms of neuroprotective effects of therapeutic acetylcholinesterase inhibitors used in treatment of Alzheimer's disease2006
- Author(s)
  Takatori, Y
- Journal Title
  
  YAKUGAKU ZASSHI 126・8
  
  Pages: 607-616
- NAID
  110006154972
- Data Source
  KAKENHI-PROJECT-18890220
[Journal Article] Neuroprotective action of donepezil mediated by neuronal nicotinic receptors.2006
- Author(s)
  Takada-Takatori, Yuki
- Journal Title
  
  Psychogeriatrics 6・Suppl2
  
  Pages: 47-56
- Data Source
  KAKENHI-PROJECT-18890220
[Journal Article] Mechanisms of nicotinic receptor-mediated neuroprotection by acetylcholinesterase inhibitors against apoptotic glutamate neurotoxicity2006
- Author(s)
  Takada-Takatori, Yuki
- Journal Title
  
  Neuroscience Research 55・Suppl1
  
  Pages: 101-101
- Data Source
  KAKENHI-PROJECT-18890220
[Presentation] Donepezil decreases tau hyperphosphorylation induced by hypothermia in vivo and in vitro2019
- Author(s)
  Ryosuke Nakanishi, Yuki Takada-Takatori, Kayoko Takara, Konami Takashima, Katsuharu Tsuchida, Yasuhiko Izumi, Akinori Akaike, Tomohiro Miyasaka, Toshiaki Kume
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-17K08323
[Presentation] ドネペジルは細胞内輸送制御分子SNX33の発現量を増大してAβ産生を抑制する2018
- Author(s)
  高鳥悠記、中川翔太、木全璃子、名尾洋亮、泉安彦、土田勝晴、赤池昭紀、久米利明
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08323
[Presentation] Neuroprotective effect of tropisetron other than through α7 nicotinic acetylcholine receptor2013
- Author(s)
  南奈央子、高鳥悠記、泉安彦、赤池昭紀、久米利明
- Organizer
  第7回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東北大学片平キャンパス　さくらホール
- Data Source
  KAKENHI-PROJECT-25860069
[Presentation] 内在性α7型ニコチン受容体アロステリックリガンドSLURP-1の免疫器官における発現とリンパ球コリン作動系活性の調節2013
- Author(s)
  角野有紀、堀口和秀、三澤日出巳、森脇康博、高鳥悠記、川島紘一郎、藤井健志
- Organizer
  第63回日本薬学会近畿支部総会・大会
- Place of Presentation
  同志社女子大学京都・京田辺市
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23590121
[Presentation] 青ジソ由来Nrf2-ARE経路活性化物質のヒト表皮細胞への酸化ストレスに対する保護作用2013
- Author(s)
  上里彩夏、高鳥悠記、武政翔大、泉安彦、赤池昭紀、久米利明、藤井健志
- Organizer
  第63回日本薬学会近畿支部総会・大会
- Place of Presentation
  同志社女子大学京都・京田辺市
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23590121
[Presentation] Regulatory mechanisms of acetylcholine synthesis and release in T cells2011
- Author(s)
  Fujii T, Takada-Takatori Y, Kawashima K
- Organizer
  3^<rd> International Symposium on Non-Neuronal acetylcholine
- Place of Presentation
  オランダ・グローニンゲン
- Year and Date
  2011-08-25
- Data Source
  KAKENHI-PROJECT-23590121
[Presentation] SLURP-1によるTリンパ球からのアセチルコリン遊離促進2011
- Author(s)
  藤井健志、高鳥悠記、川島紘一郎
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  神奈川
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-20590096
[Presentation] メディエートフォアを介するT細胞からのアセチルコリン遊離機構2010
- Author(s)
  藤井健志、高鳥悠記、川島紘一郎
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-20590096
[Presentation] リンパ球における非神経性コリン作動系の発現と免疫調節機構2009
- Author(s)
  藤井健志、高鳥悠記、川島紘一郎
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-20590096
[Presentation] ドネペジル慢性処置した大脳皮質ニューロンにおける低濃度ドネペジル前処置の神経保護作用機序2008
- Author(s)
  高鳥悠記
- Organizer
  第81回日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-18890220
[Presentation] α7ニコチン受容体やphosphatidylinositol 3-kinase経路を介したドネペジル慢性処置の作用2007
- Author(s)
  高鳥悠記
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-18890220
[Presentation] ニューロン保護・新生におけるニコチン受容体シグナルの役割の解明
- Author(s)
  赤池昭紀、久米利明、泉安彦、高鳥悠記
- Organizer
  喫煙科学研究財団研究発表会
- Place of Presentation
  京王プラザホテル（東京）
- Data Source
  KAKENHI-PROJECT-25860069
[Presentation] ニューロンにおけるドネペジルのglycogen synthase kinase-3βの活性抑制作用
- Author(s)
  牧谷洸希、高鳥悠記、南奈央子、河本啓、泉安彦、赤池昭紀、久米利明
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-25860069

1. FUJII Takeshi (80255380)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. KAWASHIMA Koichiro (70095008)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. MATSUI Minoru (50282611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 久米利明 (10303843)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. YAMADA Shizuo (80106434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKEUCHI Tadayoshi (00171611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 宮坂知宏 (90342857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. IZUMI Yasuhiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 赤池昭紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

TAKATORI Yuki 高鳥 悠記

高鳥 悠記 タカトリ ユキ

Takada-Takatori Yuki 高鳥 悠記

Research Projects

Research Products

Co-Researchers

アルツハイマー病の治療・予防薬開発に向けた新規創薬ターゲットの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel therapeutic agents for Alzheimer's disease based on analysis of neuroprotective signals and regulation of tau phosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel mechanism through regulation of tau phosphorylation and neuroprotective effect by drugs for the treatment of Alzheimer's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction between vacuolar H+ ATPase and lymphocytic cholinergic system in regulation of immune function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of lymphocytic cholinergic system in regulation of fat metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルツハイマー病治療薬の新規神経保護作用機序に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Nicotinic acetylcholine receptor signaling in neuroprotection2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Potential protective effect of highly bioavailable curcumin on an oxidative stress model induced by microinjection of sodium nitroprusside in mice brain.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death2014

Author(s)

Journal Title

Data Source

[Journal Article] Endogenous dopamine is involved in the herbicide paraquat-induced dopaminergic cell death.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Staurosporine induces dopaminergic neurite outgrowth through AMP-activated protein kinase/mammalian target of rapamycin signaling pathway.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective Effect of Luteolin on an Oxidative-Stress Model Induced by Microinjection of Sodium Nitroprusside in Mice2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

TAKATORI Yuki 高鳥悠記

高鳥悠記タカトリユキ

Takada-Takatori Yuki 高鳥悠記