Hirata Hiroaki 平田宏聡

Researcher Number	90414028
Other IDs
Affiliation (Current)	2022: 金沢工業大学, バイオ・化学部, 教授
Affiliation (based on the past Project Information) *help	2022: 金沢工業大学, バイオ・化学部, 教授 2019 – 2021: 名古屋大学, 医学系研究科, 特任講師
Review Section/Research Field	Principal Investigator 0702:Biology at cellular to organismal levels, and related fields / Basic Section 90110:Biomedical engineering-related / Transformative Research Areas, Section (III) Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator メカノバイオロジー / アドヘレンスジャンクション / 細胞協同現象 / 葉状仮足 / Rac1 / 焦点接着斑 / アクトミオシンファイバー / 組織伸展 / 細胞増殖 / 上皮細胞 … More / 腫瘍細胞塊 / 力学刺激 / 三次元培養 / グリオーマ / 圧縮刺激 … More Except Principal Investigator メカノセンシング / 研究者ネットワーク / 領域会議 / 研究会 Less

プレッシオ脳神経科学の促進・発展
- Principal Investigator
  
  野々村恵子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Institute of Technology
  National Institute for Basic Biology
Compressive stress against brain tumors: its effect on tumor cell growth and the underlying molecular mechanismPrincipal Investigator
- Principal Investigator
  
  平田宏聡
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kanazawa Institute of Technology
  Nagoya University
Tissue deformation-dependent regulation of cell proliferation: distinct roles of cell-substrate and cell-cell adhesionsPrincipal Investigator
- Principal Investigator
  
  平田宏聡
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  Nagoya University
Mechanism for coordination of cell motility and proliferation in epithelial cells: role of intercellular mechanical interactionPrincipal Investigator
- Principal Investigator
  
  Hirata Hiroaki
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0702:Biology at cellular to organismal levels, and related fields
- Research Institution
  Nagoya University

All 2021 2020 2019

All Journal Article Presentation

[Journal Article] Anti-Malignant Effect of Tensile Loading to Adherens Junctions in Cutaneous Squamous Cell Carcinoma Cells2021
- Author(s)
  Dobrokhotov Oleg、Sunagawa Masaki、Torii Takeru、Mii Shinji、Kawauchi Keiko、Enomoto Atsushi、Sokabe Masahiro、Hirata Hiroaki
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 728383-728383
- DOI
  10.3389/fcell.2021.728383
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12596
[Journal Article] Cell mechanosensing underlies homeostasis of multicellular systems2020
- Author(s)
  Nonomura Keiko、Hirata Hiroaki
- Journal Title
  
  BIOPHYSICS
  
  Volume: 17 Issue: 0 Pages: 100-102
- DOI
  10.2142/biophysico.bsj-2020019
  10.2142/biophysico.BSJ-2020019
- NAID
  130007919803
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12596, KAKENHI-PROJECT-19K23748
[Journal Article] MMP24 as a Target of YAP Is a Potential Prognostic Factor in Cancer Patients2020
- Author(s)
  Wataru Sugimoto、Katsuhiko Itoh、Hiroaki Hirata、Yoshinori Abe、Takeru Torii、Yasumasa Mitsui、Yemima Budirahardja、Nobuyuki Tanaka、Keiko Kawauchi
- Journal Title
  
  Bioengineering
  
  Volume: 7 Pages: 18-18
- DOI
  10.3390/bioengineering7010018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23748, KAKENHI-PROJECT-17H04054, KAKENHI-PROJECT-19J21096, KAKENHI-PROJECT-18K06231
[Journal Article] Coordination between Cell Motility and Cell Cycle Progression in Keratinocyte Sheets via Cell-Cell Adhesion and Rac12020
- Author(s)
  Hirata Hiroaki、Dobrokhotov Oleg、Sokabe Masahiro
- Journal Title
  
  iScience
  
  Volume: 23 Pages: 101729-101729
- DOI
  10.1016/j.isci.2020.101729
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K12596, KAKENHI-PROJECT-19K23748
[Journal Article] Tension-dependent Generation of Biochemical Signals on Actomyosin Fibers2020
- Author(s)
  Hiroaki Hirata、Masahiro Sokabe
- Journal Title
  
  Biophysics
  
  Volume: 60 Issue: 2 Pages: 089-093
- DOI
  10.2142/biophys.60.089
- NAID
  130007818289
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23748
[Journal Article] 細胞増殖の接触阻害における物理的因子の役割2020
- Author(s)
  平田宏聡、Oleg Dobrokhotov、曽我部正博
- Journal Title
  
  実験医学
  
  Volume: 38 Pages: 93-99
- Data Source
  KAKENHI-PROJECT-19K23748
[Presentation] 表皮細胞単層中での細胞周期進行と細胞運動の協調制御：細胞間接着とRac1の役割2021
- Author(s)
  平田宏聡、Oleg Dobrokhotov、曽我部正博
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12596
[Presentation] 表皮細胞増殖の接触阻害における細胞間引張力の役割と表皮がんでの破綻2021
- Author(s)
  平田宏聡、Oleg Dobrokhotov、砂川真輝、榎本篤、曽我部正博
- Organizer
  第5回日本メカノバイオロジー学会
- Data Source
  KAKENHI-PROJECT-20K12596
[Presentation] Tension at adherens junction inhibits proliferation and promotes differentiation of keratinocyte carcinoma cells2020
- Author(s)
  Oleg Dobrokhotov、曽我部正博、平田宏聡
- Organizer
  日本生物物理学会第58回年会
- Data Source
  KAKENHI-PROJECT-20K12596
[Presentation] 細胞外基質硬度による焦点接着斑―アクチン骨格系調節の分子・生物物理基盤2020
- Author(s)
  平田宏聡
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12596
[Presentation] Molecular and biophysical bases for modulation of the focal adhesion-actin cytoskeleton system in response to extracellular substrate rigidity2020
- Author(s)
  平田宏聡
- Organizer
  第53回生物機械システム研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12596
[Presentation] 角化細胞の増殖の接触阻害には接着結合の引張力が必須である2020
- Author(s)
  平田宏聡、Oleg Dobrokhotov、曽我部正博
- Organizer
  日本生物物理学会第58回年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23748
[Presentation] Molecular and biophysical bases for modulation of the focal adhesion-actin cytoskeleton system in response to extracellular substrate rigidity2020
- Author(s)
  平田宏聡
- Organizer
  第53回生物機械システム研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23748
[Presentation] 細胞外基質硬度による焦点接着斑―アクチン骨格系調節の分子・生物物理基盤2020
- Author(s)
  平田宏聡
- Organizer
  第43回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23748
[Presentation] 角化細胞の増殖の接触阻害には接着結合の引張力が必須である2020
- Author(s)
  平田宏聡、Oleg Dobrokhotov、曽我部正博
- Organizer
  日本生物物理学会第58回年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K12596
[Presentation] RhoA activation induces cell cycle exit and differentiation of skin cancer cells2019
- Author(s)
  Oleg Dobrokhotov、Masahiro Sokabe、Hiroaki Hirata
- Organizer
  日本生物物理学会第57回年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K23748

1. 野々村恵子 (70799246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 森松賢順 (70580934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中澤直高 (90800780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KAWAUTI Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 田中信之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirata Hiroaki 平田 宏聡

Research Projects

Research Products

Co-Researchers

プレッシオ脳神経科学の促進・発展

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Compressive stress against brain tumors: its effect on tumor cell growth and the underlying molecular mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Tissue deformation-dependent regulation of cell proliferation: distinct roles of cell-substrate and cell-cell adhesionsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism for coordination of cell motility and proliferation in epithelial cells: role of intercellular mechanical interactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Anti-Malignant Effect of Tensile Loading to Adherens Junctions in Cutaneous Squamous Cell Carcinoma Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell mechanosensing underlies homeostasis of multicellular systems2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] MMP24 as a Target of YAP Is a Potential Prognostic Factor in Cancer Patients2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coordination between Cell Motility and Cell Cycle Progression in Keratinocyte Sheets via Cell-Cell Adhesion and Rac12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tension-dependent Generation of Biochemical Signals on Actomyosin Fibers2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] 細胞増殖の接触阻害における物理的因子の役割2020

Author(s)

Journal Title

Data Source

[Presentation] 表皮細胞単層中での細胞周期進行と細胞運動の協調制御：細胞間接着とRac1の役割2021

Author(s)

Organizer

Data Source

[Presentation] 表皮細胞増殖の接触阻害における細胞間引張力の役割と表皮がんでの破綻2021

Author(s)

Organizer

Data Source

[Presentation] Tension at adherens junction inhibits proliferation and promotes differentiation of keratinocyte carcinoma cells2020

Author(s)

Organizer

Data Source

[Presentation] 細胞外基質硬度による焦点接着斑―アクチン骨格系調節の分子・生物物理基盤2020

Author(s)

Organizer

Data Source

[Presentation] Molecular and biophysical bases for modulation of the focal adhesion-actin cytoskeleton system in response to extracellular substrate rigidity2020

Hirata Hiroaki 平田宏聡