Oishi Motoi 大石基

… Alternative Names

OISHI Motoi 大石基

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Researcher Number	90419242
Other IDs
Affiliation (Current)	2025: 筑波大学, 数理物質系, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 筑波大学, 数理物質系, 准教授 2011 – 2017: 筑波大学, 数理物質系, 講師 2010: 筑波大学, 大学院・数理物質科学研究科, 講師 2008: University of Tsukuba, 大学院数理物, 講師 2007 – 2008: University of Tsukuba, 大学院・数理物質科学研究科, 講師 2006: 筑波大学, 大学院数理物質科学研究科, 助手
Review Section/Research Field	Principal Investigator Nanomaterials/Nanobioscience / Basic Section 28050:Nano/micro-systems-related / Nanobioscience Except Principal Investigator Science and Engineering / Biomedical engineering/Biological material science
Keywords	Principal Investigator 金ナノ粒子 / DNA / ナノ粒子 / ナノ界面 / siRNA / ナノマシン / 感染症 / 診断 / DNA ナノマシン / アルツハイマー認知症 … More / miRNA / 酵素 / センサー / 19F-NMR / 磁性粒子 / ＤＮＡ / 19Ｆ－ＮＭＲ / ナノゲル粒 / 可視化 / 送達 / ナノゲル粒子 / ナノデバイス / ポリエチレングリコール(PEG) / ブロック共重合体 / アポトーシス / ポリエチレングリコール / ポリアミン … More Except Principal Investigator 免疫沈降 / ポリマーブラシ / PEG / バイオナノ粒子 / バイオインターフェース / SPR / XPS / DDS / 遺伝子治療 / 遺伝子診断 / オリゴ核酸 / RNA精製 / PCR / ストレプトアビジン / センサー / 分子認識 / ELISA / ブラシ / ハイブリッド密生層 / 表面プラズモン共鳴 / ナノ酵素 / 免疫診断 / ナノ診断 Less

Development of Point of Care Testing for Infectious Diseases Based on DNA Walkers with Precisely Designed NanoparticlesPrincipal Investigator
- Principal Investigator
  
  Oishi Motoi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28050:Nano/micro-systems-related
- Research Institution
  University of Tsukuba
Precise control of nano-interface for diagnosis of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  OISHI Motoi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanobioscience
- Research Institution
  University of Tsukuba
Development of 19F-NMR-Based Multiplex Focused Gene Diagnostic SystemsPrincipal Investigator
- Principal Investigator
  
  OISHI Motoi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  University of Tsukuba
Design and Preparation of a Nanodevice Containing Gold Nanoparticles for Delivery and Imaging of Nucleic AcidsPrincipal Investigator
- Principal Investigator
  
  OISHI Motoi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  University of Tsukuba
遺伝子センシングを可能とするバイオナノ粒子の材料設計
- Principal Investigator
  
  長崎幸夫
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  University of Tsukuba
Design of Core-Shell Gold Nanoparticles for the Detection and Induction of apoptosis in vivoPrincipal Investigator
- Principal Investigator
  
  OISHI Motoi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  University of Tsukuba
Bionanosensing based on Bio-frontier Surface
- Principal Investigator
  
  NAGASAKI Yukio
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  University of Tsukuba

[Book] Stimuli-Responsive PEGylated Nanogels for Smart Nanomedicines Chapter 5 in the book entitled Biomedical Applications of Hydrogels Handbook2010
- Author(s)
  M. Oishi and Y. Nagasaki
- Publisher
  Springer Inc
- Data Source
  KAKENHI-PROJECT-22710114
[Book] Biomedical Applications of Hydrogels Handbook2010
- Author(s)
  Motoi Oishi
- Publisher
  Springer Inc.New York
- Data Source
  KAKENHI-PROJECT-22710114
[Book] Macromolecular Chemistry2009
- Author(s)
  Motoi Oishi
- Publisher
  Nov Science Publisher Inc. New York(in press)
- Data Source
  KAKENHI-PROJECT-19710108
[Book] "Block Copolymer Synthesis of Nanoscale Drug and Gene Delivery", in Nanotechnology in Drug Delivery, Ed. byMelgaradt M.de Villiers,Porn anong Aramwit,Glen S.Kwon2008
- Author(s)
  大石基、長崎幸夫
- Publisher
  Springer,New York,2008
- Data Source
  KAKENHI-PROJECT-18200033
[Book] ナノゲルによるピンポイント治療・診断システムへの展開【応用編】第6章, ゲルの微細加工と細胞のマイクロパターニング(吉田亮監修)2008
- Author(s)
  大石基、長崎幸夫
- Publisher
  (株)シーエムシー出版
- Data Source
  KAKENHI-PROJECT-18200033
[Book] Block Copolymer Synthesis of Nanoscale Drug and Gene Delivery2008
- Author(s)
  Motoi Oishi, Yukio Nagasaki
- Publisher
  in Nanotechnology in Drug Delivery, Ed. by Melgaradt M. de Villiers, Pornanong Aramwit, Glen S. Kwon, Springer, New York
- Data Source
  KAKENHI-PROJECT-18200033
[Book] "Smart Hybrid Nanoparticles Based on Stimuli-Responsive PEGylated Nanogels Containing Metal Nanoparticles for Biomedical Applications" in the book entitled "Modern Trends in Macromolecular Chemistry" (Edited by Frank Columbus)
- Author(s)
  Motoi Oishi and Yukio Nagasaki
- Publisher
  Nov Science Publisher Inc. New York(in press)
- Data Source
  KAKENHI-PROJECT-19710108
[Journal Article] Long-term Cryopreservation of Ready-to-Use DNA-Modified Gold Nanoparticle Derivatives: Effect of Preservation Temperature on Their DNA Dissociation and Functional Stability2022
- Author(s)
  Shotaro Juji and Motoi Oishi
- Journal Title
  
  Bulletin of the Chemical Society of Japan
  
  Volume: 95 Issue: 3 Pages: 410-412
- DOI
  10.1246/bcsj.20210437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02589
[Journal Article] Acceleration of DNA Hybridization Chain Reactions on 3D Nano-interfaces of Magnetic Particles and Their Direct Application in the Enzyme-Free Amplified Detection of microRNA2021
- Author(s)
  Motoi Oishi and Shotaro Juji and
- Journal Title
  
  ACS Applied Materials & Interfaces
  
  Volume: 13 Issue: 30 Pages: 35533-35544
- DOI
  10.1021/acsami.1c09631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H02589
[Journal Article] An Efficient Particle-Based DNA Circuit System: Catalytic Disassembly of DNA/PEG-Modified Gold Nanoparticle-Magnetic Bead Composites for Colorimetric Detection of miRNA2016
- Author(s)
  Motoi Oishi and Satomi Sugiyama
- Journal Title
  
  Small
  
  Volume: 12 Issue: 37 Pages: 5153-5158
- DOI
  10.1002/smll.201601741
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K04632
[Journal Article] Kinetic Study of DNA Hybridization on DNA-modified Gold Nanoparticles with Engineered Nano-Interfaces2015
- Author(s)
  Akari Takashima and Motoi Oishi
- Journal Title
  
  RSC Advances
  
  Volume: 5 Issue: 93 Pages: 76014-76018
- DOI
  10.1039/c5ra13116b
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K04632
[Journal Article] Ultrasensitive Detection of DNA and RNA Based on Enzyme-Free Click Chemical Ligation Chain Reaction on Dispersed Gold Nanoparticles2014
- Author(s)
  Daiki Kato and Motoi Oishi
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 10 Pages: 9988-9997
- DOI
  10.1021/nn503150w
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24510165
[Journal Article] Enzyme-Free Fluorescent-Amplified Aptasensors Based on Target-Responsive DNA Strand Displacement via Toehold-Mediated Click Chemical Ligation2014
- Author(s)
  Motoi Oishi, Shingo Nakao, and Daiki Kato
- Journal Title
  
  Chemical Communications
  
  Volume: 50 Pages: 991-993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510165
[Journal Article] Rational Design of a Fluorescence-Amplified Aptasensor Based on Enzyme-Assisted Target Recycling Strategy2013
- Author(s)
  Shingo Nakao and Motoi Oishi
- Journal Title
  
  Chemistry Letters
  
  Volume: 42 Issue: 10 Pages: 1122-1124
- DOI
  10.1246/cl.130439
- NAID
  10031201282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24510165
[Journal Article] Amemiya: Dependence of Swelling Behavior of pH-responsive PEG-modified Nanogel on Cross-link Density2012
- Author(s)
  Goshu Tamura, Yuya Shinohara, Atushi Tamura, Yusuke Sanada, Motoi Oishi, Isamu Akiba, Yukio Nagasaki, Kazuo Sakurai, and Yoshiyuki
- Journal Title
  
  Polymer Journal
  
  Volume: Vol.44,No.3 Issue: 3 Pages: 240-244
- DOI
  10.1038/pj.2011.123
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20106011, KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-22710114, KAKENHI-PROJECT-24659920
[Journal Article] Systemic delivery of siRNA to tumors using a lipid nanoparticle containing a tumor-specific cleavable PEG-lipid2011
- Author(s)
  Hiroto Hatakeyama, Hidetaka Akita, Erika Itoh, Yasuhiro Hayashi, Motoi Oishi, Yukio Nagasaki, R. Danev, K. Nagayama, N. Kaji, H. Kikuchi, Y. Baba, Harashima H
- Journal Title
  
  Biomaterials
  
  Volume: 32(18) Issue: 18 Pages: 4-4
- DOI
  10.1016/j.biomaterials.2011.02.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21240050, KAKENHI-PROJECT-22710114
[Journal Article] ガンのピンポイントナノ診断・治療のための刺激応答性ナノゲル粒子2010
- Author(s)
  大石基
- Journal Title
  
  ナノ学会会報
  
  Volume: 8 Pages: 91-96
- NAID
  40017096005
- Data Source
  KAKENHI-PROJECT-22710114
[Journal Article] Stimuli-Responsive Smart Nanogels for Cancer Diagnostics and Therapy2010
- Author(s)
  M. Oishi and Y. Nagasaki
- Journal Title
  
  Nanomedicine
  
  Volume: 5 Issue: 3 Pages: 451-468
- DOI
  10.2217/nnm.10.18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710114
[Journal Article] Fluorescence-Quenching PEGylated Nanogel Containing Gold Nanoparticles for Monitoring the Cancer Response to Therapy2009
- Author(s)
  Oishi M, Tamura A, Nakamura T, Nagasaki Y
- Journal Title
  
  Advanced Functional Materials 19(6)
  
  Pages: 827-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] A Smart Nanoprobe Based on Fluorescence-Quenching PEGylated Nanogel Containing Gold Nanoparticles for Monitoring the Cancer Response to Therapy2009
- Author(s)
  Motoi Oishi, Atsushi Tamura, Takahito Nakamura, and Yukio Nagasaki
- Journal Title
  
  Adv. Funct. Mater. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710108
[Journal Article] Novel Tumor-specific 19F-MRS/I Nanoprobe based on pH-Responsive PEGylated Nanogel : pH-Dependent 19F-Magnetic Resonance Studies2009
- Author(s)
  Oishi M, Sumitani S, Bronich T K., Kabanov A V., Boska M D., Nagasaki Y
- Journal Title
  
  Chemistry Letters
  
  Pages: 128-129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] A Smart Nanoprobe Based on Fluorescence-Quenching PEGylated Nanogel Containing Gold Nanoparticles for Monitoring the Cancer Response to Therapy2009
- Author(s)
  Motoi Oishi
- Journal Title
  
  Adv. Funct. Mater 19
  
  Pages: 827-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710108
[Journal Article] Structure and Activity Assay of Nanozymes Prepared by the Co-immobilization of Practically Useful Enzymes and Hydrophilic Block Copolymers on Gold Nanoparticles.2008
- Author(s)
  Yuan X , Iijima M, Oishi M , Nagasaki Y
- Journal Title
  
  Langmuir 24
  
  Pages: 6903-6909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Completely Dispersible PEGylafed Gold Nanoparticles Under Physiological Conditions: Modification of Gold Nanoparticles With Precisely Controlled PEG-b-polyamine.2008
- Author(s)
  宮本大輔、大石基、吉本敬太郎、長崎幸夫、他
- Journal Title
  
  Langmuir 24
  
  Pages: 5010-5017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Structure and Activity Assay of Nanozymes Prepared by the Co-I mmobilization of Practically Useful Enzymes and Hydrophic Block Cootymers on Gold Nanoparticles.2008
- Author(s)
  原暁非、大石基、長崎幸夫、他
- Journal Title
  
  Langmuir 24
  
  Pages: 6903-6909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Completely Dispersible PEGylated Gold Nanoparticles under Physiological Conditions : Modification of Gold Nanoparticles with Precisely Controlled PEG-b-Polyamine2008
- Author(s)
  Daisuke Miyamoto, Motoi Oishi, Keiji Kojima, Keitaro Yoshimoto, and Yukio Nagasaki
- Journal Title
  
  Langmuir 24
  
  Pages: 5010-5017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710108
[Journal Article] Enhanced Growth Inhibition of Hepatic Multicellular Tumor Spheroids by Lactosylated Poly (ethylene glycol)-siRNA Conjugate Formulated in PEGylated Polyplexes.2007
- Author(s)
  Oishi Motoi, Nagasaki Yukio, Nishiyama Nobuhiro, Itaka Keiji, Takagi Motoki, Shimamoto Akira, Furuichi Yasuhiro, Kataoka Kazunori
- Journal Title
  
  Chem Med Chem 2
  
  Pages: 1290-1297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Endosomal Release and Intracellular Delivery of Anticancer Drugs Using pH-Sensitive PEGylated Nanogels2007
- Author(s)
  大石基、長崎幸夫, 他
- Journal Title
  
  Journal of Materials Chemistry 17
  
  Pages: 3720-3725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021007
[Journal Article] Endosomal Release and Intracellular Delivery of Anticancer Drugs Using pH-Sensitive PEGylated Nanogels2007
- Author(s)
  大石基、長崎幸夫、他
- Journal Title
  
  Journal of Materials Chemistry 17
  
  Pages: 3720-3725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] On-Off Regulation of 19F Magnetic Resonance Signals Based on pH-Sensitive PEGylated Nanogels for Potential Tumor-Specific Smart 19FMRI Probes2007
- Author(s)
  大石基、長崎幸夫, 他
- Journal Title
  
  Bioconjugate Chemistry 18
  
  Pages: 1379-1382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19021007
[Journal Article] Synthesis, characterization, and biomedical applications of core-shell-type stimuli-responsive nanogels-Nanogel composed of poly [2-(N, N-diethylamino) ethyl methacrylate] core and PEG tethered chains.2007
- Author(s)
  Oishi Motoi, Nagasaki Yukio
- Journal Title
  
  Reactive and Functional Polymers 67
  
  Pages: 1311-1329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] On-Off Regulation of 19 F Magnetic Resonance Signals Based on pH-Sensitive PEGylated Nanogels for Potential Tumor-Specific Smart 19 F MRI Probes2007
- Author(s)
  Oishi Motoi, Sumitani Shogo, Nagasaki Yukio
- Journal Title
  
  Bioconjugate Chemistry 18
  
  Pages: 1379-1382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] One-Pot Synthesis of pH-Responsive PEGylated Nanogels Containing Gold Nanoparticles by Autoreduction of Chloroaurate Ions within Nanoreactors2007
- Author(s)
  Oishi Motoi, Hayashi Hisato, Uno Teppei, Ishii Takehiko, Iijima Michihiro, Nagasaki Yukio
- Journal Title
  
  Macromolecular Chemistry and Physics 208
  
  Pages: 1176-1182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid.2007
- Author(s)
  Hatakeyama H., Akita H., Kogure K., Oishi M., Nagasaki Y., Kihira Y., Ueno M., Kobayashi H., Kikuchi H., Harashima H
- Journal Title
  
  Gene Therapy 14
  
  Pages: 68-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid2007
- Author(s)
  長崎幸夫, 大石基
- Journal Title
  
  Gene Therapy 14
  
  Pages: 68-77
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] On-Off Regulation of 19F Magnetic Resonance Signals Based on pH-Sensitive PEGylated Nanogels for Potential Tumor-Specific Smart 19F MRI Probes2007
- Author(s)
  大石基、長崎幸夫、他
- Journal Title
  
  Bioconjugate Chemistry 18
  
  Pages: 1379-1382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Smart PEGylated gold nanoparticles for the cytoplasmic delivery of siRNA to induce enhanced gene silencing2006
- Author(s)
  長崎幸夫, 大石基
- Journal Title
  
  Chemistry Letters 35(9)
  
  Pages: 1046-1047
- NAID
  10018063296
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] pH-Responsive three-layered PEGylated polyplex micelle based on lactosylated ABC triblock copolymer as targetable and endosome-disruptive nonviral gene vector2006
- Author(s)
  長崎幸夫, 大石基
- Journal Title
  
  Bioconjugate Chemistry 17(3)
  
  Pages: 677-688
- Data Source
  KAKENHI-PROJECT-18200033
[Journal Article] Intracellular inducible alkylation system that exhibits antisense effects with greater potency and selectivity than natural oligonucleotide2006
- Author(s)
  長崎幸夫, 大石基
- Journal Title
  
  Angewandte Chemie International Edition 118(19)
  
  Pages: 3208-3212
- Data Source
  KAKENHI-PROJECT-18200033
[Patent] 複合体、試料中の対象核酸の検出方法及びキット2016
- Inventor(s)
  大石　基、杉山聡深
- Industrial Property Rights Holder
  大石　基、杉山聡深
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-123934
- Filing Date
  2016-06-22
- Data Source
  KAKENHI-PROJECT-15K04632
[Patent] 四級アミノ基を有する架橋ポリマー由来のポリマー微粒子と核酸の複合体2009
- Inventor(s)
  長崎幸夫, 田村篤志, 大石基
- Industrial Property Rights Holder
  国立大学法人筑波大学
- Industrial Property Number
  2009-004710
- Filing Date
  2009-01-13
- Data Source
  KAKENHI-PROJECT-18200033
[Patent] コレステロール低下作用を有する水溶性高分子架橋体2007
- Inventor(s)
  長崎幸夫、大石基、斯波真理子
- Industrial Property Rights Holder
  筑波大学
- Filing Date
  2007-02-09
- Data Source
  KAKENHI-PROJECT-18200033
[Patent] Preparation of Double-Stranded Nucleic Acid Conjugate of Poly(ethylene oxide) and Its Use for Drug Delivery2006
- Inventor(s)
  長崎幸夫, 大石基
- Industrial Property Rights Holder
  科学技術振興機構
- Filing Date
  2006-03-09
- Data Source
  KAKENHI-PROJECT-18200033
[Presentation] DNAバルジループ構造の導入によりバックグラウンドを低減させたDNAサーキットの構築2022
- Author(s)
  菅原匠、大石基
- Organizer
  第82回分析化学討論会
- Data Source
  KAKENHI-PROJECT-20H02589
[Presentation] バルジループを導入した DNA サーキットの最適化と酵素フリーな核酸検出2022
- Author(s)
  菅原匠、大石基
- Organizer
  分析化学会第71年会
- Data Source
  KAKENHI-PROJECT-20H02589
[Presentation] 核酸の 1 分子検出を目指した DNA 化金ナノ粒子固定化ガラス基板の調製と評価2022
- Author(s)
  木佐木大希、大石基
- Organizer
  第12回CSJ化学フェスタ2022
- Data Source
  KAKENHI-PROJECT-20H02589
[Presentation] Au-S結合によってDNAを修飾した金ナノ粒子誘導体の長期保存における安定性の評価2021
- Author(s)
  十字祥太郎、大石基
- Organizer
  日本分析化学会第70年会
- Data Source
  KAKENHI-PROJECT-20H02589
[Presentation] Point of Care Testing (POCT) for Nucleic Acids at Room Temperature & without Enzymes2020
- Author(s)
  Motoi Oishi
- Organizer
  BioJapan 2020 in Yokohama
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02589
[Presentation] 指数関数的な増幅機能を有するDNAサーキットによる酵素フリーおよび室温でのmiRNAの検出2017
- Author(s)
  大石　基、杉山聡深
- Organizer
  日本分析化学会第66回年会
- Data Source
  KAKENHI-PROJECT-15K04632
[Presentation] DNA/PEG化金ナノ粒子・磁性粒子複合体のDNAサーキットによる酵素および装置フリーなmiRNAの検出2016
- Author(s)
  大石　基、杉山聡深
- Organizer
  日本分析化学会第65回年会
- Place of Presentation
  北海道大学札幌キャンパス（北海道札幌市）
- Year and Date
  2016-09-13
- Data Source
  KAKENHI-PROJECT-15K04632
[Presentation] コロイドを用いたDNAサーキットシステム：DNA/PEG化金ナノ粒子と磁性粒子の複合体の触媒的脱会合による核酸の検出2016
- Author(s)
  大石　基、杉山聡深
- Organizer
  第67回コロイドおよび界面化学討論会
- Place of Presentation
  北海道教育大学旭川キャンパス（北海道旭川市）
- Year and Date
  2016-09-21
- Data Source
  KAKENHI-PROJECT-15K04632
[Presentation] 異なる界面構造を有するDNA化金ナノ粒子表面におけるDNAハイブリダイゼーションの速度論的研究2015
- Author(s)
  大石　基、高島明里
- Organizer
  ナノ学会第１３回大会
- Place of Presentation
  東北大学片平キャンパス(宮城県仙台市）
- Year and Date
  2015-05-11
- Data Source
  KAKENHI-PROJECT-15K04632
[Presentation] DNA/PEG共固定化金ナノ粒子界面におけるDNAハイブリダイゼーションの速度論的解析2015
- Author(s)
  大石　基、高島明里
- Organizer
  第66回コロイドおよび界面化学討論会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島県鹿児島市）
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15K04632
[Presentation] DNA化金ナノ粒子表面におけるDNAハイブリダイゼーションの速度論的解析2015
- Author(s)
  高島明里、大石　基
- Organizer
  第75回分析化学討論会
- Place of Presentation
  山梨大学甲府キャンパス(山梨県甲府市）
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-15K04632
[Presentation] DNAおよびRNAの超高感度検出を目指した金ナノ粒子表面での酵素フリー2014
- Author(s)
  大石　基
- Organizer
  ナノ学会　第12回
- Place of Presentation
  京都府宇治市　京都大学宇治キャンパス
- Data Source
  KAKENHI-PROJECT-24510165
[Presentation] 金ナノ粒子表面での酵素フリー型クリックケミカルライゲーション連鎖反応を基盤としたDNAおよびRNAの超高感度検出システムの構築2014
- Author(s)
  大石　基
- Organizer
  第74回分析化学討論会
- Place of Presentation
  福島県郡山市　日本大学工学部
- Data Source
  KAKENHI-PROJECT-24510165
[Presentation] 酵素および酵素フリーでのシグナル増強を目指した蛍光アプタマーセンサーの構築2013
- Author(s)
  大石　基
- Organizer
  日本分析化学会第62年会
- Place of Presentation
  大阪府東大阪市　近畿大学東大阪キャンパス
- Data Source
  KAKENHI-PROJECT-24510165
[Presentation] 構造スイッチングDNAアプタマー用いた酵素増強型蛍光バイオセンサーの創製2013
- Author(s)
  大石　基
- Organizer
  第73回分析化学討論会
- Place of Presentation
  北海道函館市、北海道大学函館キャンパス
- Data Source
  KAKENHI-PROJECT-24510165
[Presentation] Boron Neutron Capture Therapy Assisted by Nanoparticles : Enhanced Tumor Accumulation by Core-Polymerization with Boron-Containing Monomer2011
- Author(s)
  M. Oishi, et. al
- Organizer
  第60回高分子学会年次会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22710114
[Presentation] Design of PEGylated Polyamine Gold Nanoparticles as Nucleic Acid Drug Carriers for Systemic Cancer Gene Therapy2011
- Author(s)
  M. Oishi, et.al
- Organizer
  第60回高分子学会年次会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22710114
[Presentation] Boron Neutron Capture Therapy Assisted by Nanoparticles: Enhanced Tumor Accumulation by Core-Polymerization with Boron-Containing Monomer2011
- Author(s)
  Motoi Oishi
- Organizer
  第60回高分子学会年次会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2011-05-26
- Data Source
  KAKENHI-PROJECT-22710114
[Presentation] ピンポイント治療および診断を目指した刺激応答性PEG化ナノゲル粒子の創製2010
- Author(s)
  大石基
- Organizer
  第59回高分子学会年次会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-22710114
[Presentation] ピンポイント治療および診断を目指した刺激応答性PEG化ナノゲル粒子の創製2010
- Author(s)
  大石基
- Organizer
  第59回高分子学会年次会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2010-05-26
- Data Source
  KAKENHI-PROJECT-22710114
[Presentation] Design and Characterization of pH-Responsive PEGylated Nanogels for Potential Drug Delivery Carrier.2009
- Author(s)
  Tamura M, Tamura A, Oishi M, Nagasaki Y
- Organizer
  ISAT-3/PTW-3, International
- Place of Presentation
  Tokyo International Exchange Center, Tokyo
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-18200033
[Presentation] マルチ刺激応答性ナノゲルリアクターを用いた金ナノ粒子の調製と応用2008
- Author(s)
  中村隆仁、大石基、長崎幸夫
- Organizer
  第57回高分子討論会、大阪市立大学
- Place of Presentation
  大阪、口頭(3T02)
- Year and Date
  2008-09-26
- Data Source
  KAKENHI-PROJECT-18200033
[Presentation] ナノプロープ粒子によるガンおよびアポトーシスのピンポイントイメージング2008
- Author(s)
  大石基
- Organizer
  第17回バイオイメージング学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] ナノプローブ粒子によるガンおよびアポトーシスのピンポイントイメージング2008
- Author(s)
  大石基、長崎幸夫
- Organizer
  第17回バイオイメージング学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] pH-Responsive PEGylated Nanogels as a Smart Nanodevice for Cancer Diagnosis and Therapy2008
- Author(s)
  Motoi Oishi and Yukio Nagasaki
- Organizer
  236th ACS National Meeting (8th International Biorelated polymer Symposium)
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] 細胞内環境およびシグナルに応答するPEG化ナノゲル粒子によるバイオイメージング2008
- Author(s)
  大石基
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] PEG 化金コロイドによるsiRNA 送達システムの構築2008
- Author(s)
  大石基、宮本大輔、中尾上純平、狩野光伸、長崎幸夫
- Organizer
  遺伝子・デリバリー研究会第8回シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] pH ではたらく機能性ナノゲル2008
- Author(s)
  大石基
- Organizer
  高分子学会関東支部第38回茨城地区活動講演会
- Place of Presentation
  つくば
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] pHではたらく機能性ナノゲル2008
- Author(s)
  大石基
- Organizer
  高分子学会関東支部第38回茨城地区活動講演会
- Place of Presentation
  つくば
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] 金ナノ粒子分散安定性向上のためのN6PEG/金ナノ粒子複合化評価2008
- Author(s)
  山中千恵、宮本大輔、大石基、長崎幸夫
- Organizer
  第2回ポリスケールテクノロジーワークショップ
- Place of Presentation
  野田
- Year and Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] PEG化金コロイドによるsiRNA送達システムの構築2008
- Author(s)
  大石基
- Organizer
  遺伝子・デリバリー研究会第8回シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2008-05-09
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] 金ナノ粒子分散安定性向上のためのN6PEG/金ナノ粒子複合化評価2008
- Author(s)
  大石基
- Organizer
  第2回ポリスケールテクノロジーワークショップ
- Place of Presentation
  東京理科大学(野田キャンパス)
- Year and Date
  2008-03-07
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] 細胞内環境およびシグナルに応答するPEG 化ナノゲル粒子によるバイオイメージング2008
- Author(s)
  大石基、長崎幸夫
- Organizer
  第57回高分子討論会
- Place of Presentation
  大阪
- Year and Date
  2008-09-24
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] 細胞内環境応答性PEG化金ナノ粒子によるsiRNAの細胞内デリバリー2007
- Author(s)
  大石基
- Organizer
  第56回高分子年次会
- Place of Presentation
  京都国際会議場
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] ポリエチレングリコール. アルキルアミン, 金属表面, 金ナノ粒子2007
- Author(s)
  古性均、大石基、長崎幸夫
- Organizer
  第56回高分子学会年次会
- Place of Presentation
  京都, (国内ポスター発表、3Pb186)
- Year and Date
  2007-05-31
- Data Source
  KAKENHI-PROJECT-18200033
[Presentation] 胞内環境応答性PEG化金ナノ粒子によるsiRNAの細胞内デリバリー2007
- Author(s)
  大石基、中尾上純平、長崎幸夫
- Organizer
  第56回高分子年次会
- Place of Presentation
  京都
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-19710108
[Presentation] 金ナノ粒子を用いた新しい酵素複合体の調製と特性評価2007
- Author(s)
  原暁非、飯島道弘(小山高専)、大石基、長崎幸夫
- Organizer
  第56回高分子討論会、名古屋工業大学
- Place of Presentation
  名古屋、口頭(3V13)
- Year and Date
  2007-09-21
- Data Source
  KAKENHI-PROJECT-18200033
[Presentation] コレステロール吸着剤を目指したコアーシェル型ナノゲルの創成2007
- Author(s)
  長崎幸夫、吉田吉行、大石基、斯波真理子
- Organizer
  第23回日本DDS学会
- Place of Presentation
  熊本 (国内口頭発表、2-C-28)
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-18200033
[Presentation] DNAクリックケミカルライゲーションを用いたmiRNAの検出
- Author(s)
  大石基, 高島明里
- Organizer
  日本分析化学会第63年会
- Place of Presentation
  広島大学
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-24510165
[Presentation] 金ナノ粒子表面での酵素フリー型クリックケミカルライゲーション連鎖反応を基盤としたDNAおよびRNAの超高感度検出システムの構築
- Author(s)
  加藤大喜, 大石基
- Organizer
  第74回日本分析化学討論会
- Place of Presentation
  日本大学、郡山
- Year and Date
  2014-05-24 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-24510165
[Presentation] スマートナノデバイスによるガンのピンポイント診断・治療システムの開発
- Author(s)
  大石　基
- Organizer
  第４回つくばグリーンイノベーションフォーラム「バイオサイエンス」
- Place of Presentation
  茨城県つくば市、筑波大学
- Data Source
  KAKENHI-PROJECT-24510165

1. NAGASAKI Yukio (90198309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
2. YOSHIMOTO Keitaro (60392172)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. MIYAMOTO Daisuke (30392145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. GEN Gyouhi (60422185)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. SUGIYAMA Satomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Oishi Motoi 大石 基

OISHI Motoi 大石 基

Research Projects

Research Products

Co-Researchers

Development of Point of Care Testing for Infectious Diseases Based on DNA Walkers with Precisely Designed NanoparticlesPrincipal Investigator

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Precise control of nano-interface for diagnosis of Alzheimer's diseasePrincipal Investigator

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Development of 19F-NMR-Based Multiplex Focused Gene Diagnostic SystemsPrincipal Investigator

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Design and Preparation of a Nanodevice Containing Gold Nanoparticles for Delivery and Imaging of Nucleic AcidsPrincipal Investigator

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遺伝子センシングを可能とするバイオナノ粒子の材料設計

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Design of Core-Shell Gold Nanoparticles for the Detection and Induction of apoptosis in vivoPrincipal Investigator

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Bionanosensing based on Bio-frontier Surface

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[Book] Stimuli-Responsive PEGylated Nanogels for Smart Nanomedicines Chapter 5 in the book entitled Biomedical Applications of Hydrogels Handbook2010

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[Book] Biomedical Applications of Hydrogels Handbook2010

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[Book] Macromolecular Chemistry2009

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[Book] "Block Copolymer Synthesis of Nanoscale Drug and Gene Delivery", in Nanotechnology in Drug Delivery, Ed. byMelgaradt M.de Villiers,Porn anong Aramwit,Glen S.Kwon2008

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[Book] ナノゲルによるピンポイント治療・診断システムへの展開【応用編】第6章, ゲルの微細加工と細胞のマイクロパターニング(吉田亮監修)2008

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[Book] Block Copolymer Synthesis of Nanoscale Drug and Gene Delivery2008

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[Book] "Smart Hybrid Nanoparticles Based on Stimuli-Responsive PEGylated Nanogels Containing Metal Nanoparticles for Biomedical Applications" in the book entitled "Modern Trends in Macromolecular Chemistry" (Edited by Frank Columbus)

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[Journal Article] Long-term Cryopreservation of Ready-to-Use DNA-Modified Gold Nanoparticle Derivatives: Effect of Preservation Temperature on Their DNA Dissociation and Functional Stability2022

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Oishi Motoi 大石基

OISHI Motoi 大石基