SHIRAFUJI Yoshinori 白藤宜紀

Researcher Number	90423285
Affiliation (based on the past Project Information) *help	2011: 岡山大学, 大学病院, 助教 2009 – 2011: Okayama University, 岡山大学病院, 助教 2009 – 2010: Okayama University, 病院, 助教 2008: Okayama University, 医学部・歯学部附属病院, 助教 2007: Okayama University, 医学部歯学部・附属病院, 助教 2006: 岡山大学, 医学部・歯学部附属病院, 助手
Review Section/Research Field	Principal Investigator Dermatology Except Principal Investigator Dermatology
Keywords	Principal Investigator アルギニン / デフェンシン / ヒトβデフェンシン-3 / サイトカイン / αヘリクス / IL-8 / IL-6 / αヘリカル / メタロβラクタマーゼ産生緑膿菌 / 塩抵抗性(6)MRSA … More / 黄色ブドウ球菌(4)緑膿菌 / 黄色ブドウ球菌 / 塩抵抗性 / 抗菌活性 / HBD-3 / リコンビナント / レボフロキサシン / メタロβ産生緑膿菌 / 抗菌ペプチド … More Except Principal Investigator 接着因子 / 免疫微小環境 / ケモカイン / 腫瘍免疫 / 乳頭腫 / ウイルス / リモデリング / Th2 / 伝染性軟属腫ウイルス / Bowen病 / 日光角化症 / TSLP / 樹状細胞 / 伝染性軟属腫 / ヒト乳頭腫ウイルス / CAEBV / ウイルス発癌 / HDAC阻害 / NK細胞リンパ腫 / NK細胞増殖症 / 慢性活動性EBウイルス感染症 / リンパ腫 / 潜伏感染 / EBウイルス / NK細胞 / γδT細胞 / NKリンパ球増殖症 / T / 慢性活動性EBV感染症 / EBV / 蚊刺過敏症 / 種痘様水疱症 Less

Preferable biological milieu for the growth of viral epithelial neoplasms and its regulation
- Principal Investigator
  
  IWATSUKI Keiji
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Okayama University
Structural determinant of Humanβ-defensin-3 to stimulate cytokine/chemokine secretionPrincipal Investigator
- Principal Investigator
  
  SHIRAFUJI Yoshinori
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University
A disease spectrum induced by EB virus latent infections and the pathogenesis
- Principal Investigator
  
  IWATSUKI Keiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University
Determinants of antimicrobial activity and salt-resistance of defensinPrincipal Investigator
- Principal Investigator
  
  SHIRAFUJI Yoshinori
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University
デフェンシンの臨床応用Principal Investigator
- Principal Investigator
  
  白藤宜紀
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Okayama University

All 2011 2010 2009 2008 2006

All Journal Article Presentation

[Journal Article] Dendritic cell subsets and immunological milieu in inflammatory human papilloma virus-related skin lesions2011
- Author(s)
  Nakayama Y, Asagoe K, Yamauchi A, Yamamoto T, Shirafuji Y, Morizane S, Nakanishi G, Iwatsuki K
- Journal Title
  
  J Dermatol Sci
  
  Volume: 63 Pages: 173-183
- NAID
  10030892472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659205
[Journal Article] Cold agglutinin-induced acrocyanosis in a patient with subclinical chronic lymphocytic leukemia : a beneficial response to rituximab.2010
- Author(s)
  Shirafuji Y, et al
- Journal Title
  
  European Journal of Dermatol
  
  Volume: 20 Pages: 394-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659205
[Journal Article] Cold agglutinin-induced acrocyanosis in a patient with subclinical chronic lymphocytic leukemia : a beneficial response to rituximab.2010
- Author(s)
  Shirafuji Y, et al
- Journal Title
  
  European Journal of Dermatol
  
  Volume: 20 Pages: 394-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390307
[Journal Article] Cold agglutinin-induced acrocyanosis in a patient with subclinical chronic lymphocytic leukemia : a beneficial response to rituximab.2010
- Author(s)
  Shirafuji Y, Maeda Y, Iwatsuki K.
- Journal Title
  
  Eur J Dermatol 20
  
  Pages: 394-396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390307
[Journal Article] Elevated expression of paneth cell CRS4C in ileitis-prone sampl/YitFc mice : Regional distribution, subcellular localization, and mechanism of action.2010
- Author(s)
  Shanahan MT, Vidrich A, Shirafuji Y, Dubois CL, Henschen-Edman A, Hagen SJ, Cohn SM, Ouellette AJ
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 7493-7504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791075
[Journal Article] Elevated expression of paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action2010
- Author(s)
  Shanahan, M. T、. Vidrich, A. 、Shirafuji, Y., 他5名
- Journal Title
  
  J Biol Chem 285巻
  
  Pages: 7493-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790803
[Journal Article] Elevated expression of paneth cell CRS4C in ileitis-prone samp1/YitFc mice : Regional distribution, subcellular localization, and mechanism of action2010
- Author(s)
  Shanahan MT, Vidrich A, Shirafuji Y, Dubois CL, Henschen-Edman A, Hagen SJ, Cohn SM, Ouellette AJ
- Journal Title
  
  J Biol Chem
  
  Volume: vol 285 Pages: 7493-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791075
[Journal Article] Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins : solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.2006
- Author(s)
  Rosengren KJ, Daly NL, Fornander LM, Jonsson LM, Shirafuji Y, Qu X, Vogel HJ, Ouellette AJ, Craik DJ
- Journal Title
  
  J Biol Chem. 281(38)
  
  Pages: 28068-28078
- Data Source
  KAKENHI-PROJECT-18790789
[Presentation] Two Arg in C-terminal of human beta-defensin-3 are essential for the stimulation of proinflammatory cytokine secretion in keratinocytes2011
- Author(s)
  Yoshinori Shirafuji
- Organizer
  The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  京都国際会議場
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22791075
[Presentation] Two Arg in C-terminal of human beta-defensin-3 are essential for the stimulation of proinflammatory cytokine secretion in keratinocytes2011
- Author(s)
  Shirafuji Y, Yasui Y, Morizane S, Iwatsuki K
- Organizer
  The 36th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  京都
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PROJECT-22791075
[Presentation] Two Arginine residues of C-terminal are essential for the unique salt-insensitive and broad antimicrobial activities of human beta-defensin-32010
- Author(s)
  Yoko Yasui, Yoshinori Shirafuji, Keiji Iwatsuki
- Organizer
  The 35th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  和歌山
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-22791075
[Presentation] Two Arginine residues of C-terminal are essential for the unique salt-insensitive and broad antimicrobial activities of human beta-defensin-32010
- Author(s)
  Yoko Yasui, Yoshinori Shirafuji, Keiji Iwatsuki
- Organizer
  日本研究皮膚科学会第35回年次学術大会・総会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-22791075
[Presentation] Two Arginine residues in the COOH-terminal of human beta-defensin-3 affect broad antimicrobial activities and salt-resistance2009
- Author(s)
  Yoko Sakagami, Yoshinori Shirafuji, Takahi Oono, Keiji Iwatsuki
- Organizer
  The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-20790803
[Presentation] Antimicrobial activity of human beta-defensin-3 against metallo beta lactamase producing Pseudomonas. Aeruginosa2008
- Author(s)
  Yoshinori Shirafuji
- Organizer
  International Investigative Dermatology, 2008
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20790803
[Presentation] Antimicrobial Activity of Human Beta-defensin-3 Against Methicillin-resistant Staphylococcus aureus and Metallo-beta-lactamase-producing Pseudomonas aeruginosa2008
- Author(s)
  Yoko Sakagami, Yoshinori Shirafuji, Takashi Oono, Keiji Iwatsuki
- Organizer
  The 10th China-Japan Joint Meeting of Dermatology
- Place of Presentation
  Hangzhou, China
- Data Source
  KAKENHI-PROJECT-20790803
[Presentation] Antimicrobial activity of human beta-defensin-3 against metallo beta lactamase producing Pseudomonas2008
- Author(s)
  Yoshinori Shirafuji, Yoko Sakagami, Takashi Oono, Keiji Iwatsuki
- Organizer
  Aeruginosa、International Investigative Dermatology, 2008
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-20790803
[Presentation] デフェンシン活性化のメカニズム2008
- Author(s)
  白藤宜紀
- Organizer
  第4回中国研究皮膚科セミナー
- Place of Presentation
  倉敷
- Year and Date
  2008-11-16
- Data Source
  KAKENHI-PROJECT-20790803

1. IWATSUKI Keiji (80126797)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. FUJII Kazuyasu (70452571)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YAMAMOTO Takenobu (50379799)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TSUJI Kazuhide (30304356)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SUZUKI Daisuke (40549820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. AOYAMA Yumi (90291393)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MORIZANA Shin (80423333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

SHIRAFUJI Yoshinori 白藤 宜紀

Research Projects

Research Products

Co-Researchers

Preferable biological milieu for the growth of viral epithelial neoplasms and its regulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural determinant of Humanβ-defensin-3 to stimulate cytokine/chemokine secretionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A disease spectrum induced by EB virus latent infections and the pathogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Determinants of antimicrobial activity and salt-resistance of defensinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

デフェンシンの臨床応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dendritic cell subsets and immunological milieu in inflammatory human papilloma virus-related skin lesions2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cold agglutinin-induced acrocyanosis in a patient with subclinical chronic lymphocytic leukemia : a beneficial response to rituximab.2010

Author(s)

Journal Title

Data Source

[Journal Article] Cold agglutinin-induced acrocyanosis in a patient with subclinical chronic lymphocytic leukemia : a beneficial response to rituximab.2010

Author(s)

Journal Title

Data Source

[Journal Article] Cold agglutinin-induced acrocyanosis in a patient with subclinical chronic lymphocytic leukemia : a beneficial response to rituximab.2010

Author(s)

Journal Title

Data Source

[Journal Article] Elevated expression of paneth cell CRS4C in ileitis-prone sampl/YitFc mice : Regional distribution, subcellular localization, and mechanism of action.2010

Author(s)

Journal Title

Data Source

[Journal Article] Elevated expression of paneth cell CRS4C in ileitis-prone SAMP1/YitFc mice: regional distribution, subcellular localization, and mechanism of action2010

Author(s)

Journal Title

Data Source

[Journal Article] Elevated expression of paneth cell CRS4C in ileitis-prone samp1/YitFc mice : Regional distribution, subcellular localization, and mechanism of action2010

Author(s)

Journal Title

Data Source

[Journal Article] Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins : solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.2006

Author(s)

Journal Title

Data Source

[Presentation] Two Arg in C-terminal of human beta-defensin-3 are essential for the stimulation of proinflammatory cytokine secretion in keratinocytes2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Two Arg in C-terminal of human beta-defensin-3 are essential for the stimulation of proinflammatory cytokine secretion in keratinocytes2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Two Arginine residues of C-terminal are essential for the unique salt-insensitive and broad antimicrobial activities of human beta-defensin-32010

SHIRAFUJI Yoshinori 白藤宜紀