Tanaka Hideki 田中秀樹

… Alternative Names

田中秀樹タナカヒデキ

TANAKA Hideki 田中秀樹

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Researcher Number	90434076
Other IDs
Affiliation (Current)	2025: 日本大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2024: 日本大学, 歯学部, 准教授 2017 – 2022: 日本大学, 歯学部, 准教授 2006 – 2010: 日本大学, 歯学部, 専修研究員
Review Section/Research Field	Principal Investigator Periodontal dentistry / Functional basic dentistry Except Principal Investigator Basic Section 57080:Social dentistry-related / Social dentistry / Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator 歯周病 / 喫煙 / ニコチン / 破骨細胞 / サイトカイン / 炭酸脱水酵素 / マトリックス金属プロテアーゼ-9 / カテプシンK / 炭酸脱水酵素II型 / リボ多糖 / LPS … More Except Principal Investigator … More 歯周病 / メタボリックシンドローム / 上皮細胞 / 歯肉線維芽細胞 / 菊抽出物（MBP） / 電動歯ブラシ / 肝臓細胞 / FIB4 / TNF-α / 炎症性サイトカイン / 脂肪滴 / HepG2細胞 / MMP-9 / MMP-2 / MMP-1 / TGF-β / αSAM / I型コラーゲン / 肝星細胞 / 線維化 / 脂肪肝 / 細胞外基質タンパク / 高血糖 / 高血圧 / 血管新生因子 / 脂肪細胞 / 肥満 / シクロオキシゲナーゼ / リポ多糖(LPS) / プラスミノーゲンアクチベーター / プロスタグランジンE_2 / リポ多糖 (LPS) / マトリックス金属プロテアーゼ / ロスタグランジンE2 / 破骨細胞 / 骨芽細胞 / リボ多糖(LPS) / ニコチン / 喫煙 Less

セルフケアとプロフェッショナルケアによる歯周病予防の効果を高めるための基礎研究
- Principal Investigator
  
  中井久美子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Nihon University
The effects of periodontal disease on hepatic steatosis -an epidemiological and cell biological study-
- Principal Investigator
  
  KAWATO Takayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Nihon University
Cell Biology and epidemiological studies of non-obese metabolic syndrome prevention focused on periodontal disease study
- Principal Investigator
  
  KAWATO Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Nihon University
Effects of nicotine on the signal transduction in osteoclast precursorsPrincipal Investigator
- Principal Investigator
  
  TANAKA Hideki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Nihon University
Clarification of molecular mechanism that deteriorates periodontitis with alveolar bone resorption by nicotine and lipopolysaccharide.
- Principal Investigator
  
  MAENO Masao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nihon University
ニコチンとLPSが破骨細胞前駆細胞の機能発現に及ぼす影響Principal Investigator
- Principal Investigator
  
  田中秀樹
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University

All 2022 2021 2019 2018 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Impact of dental health intervention on cardiovascular metabolic risk: a pilot study of Japanese Adults2021
- Author(s)
  Yamazaki Y, Morita T, Nakai K, Konishi Y, Goto A, Yamamoto T, Seto M, Ozaki M, Tanaka H, Maeno M, Kawato T
- Journal Title
  
  Journal of Human Hypertension
  
  Volume: - Issue: 6 Pages: 500-509
- DOI
  10.1038/s41371-021-00551-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10298
[Journal Article] Effect of Periodontitis and Toothbrushing Frequency on Obesity Onset: A Cohort Study.2019
- Author(s)
  Morita T, Yamazaki Y, Seto M, Yamamoto T, Nakai K, Tanaka H, Ozaki M, Koshi R, Maeno M, Kawato T
- Journal Title
  
  Med Sci Monit.
  
  Volume: 25 Pages: 9712-9720
- DOI
  10.12659/msm.917356
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K12022
[Journal Article] Continuous compressive force induces the differentiation of osteoclasts with high levels of inorganic dissolution.2019
- Author(s)
  Matsuike R, Nakai K, Tanaka H, Ozaki M, Kanda M, Nagasaki M, Shibata C, Mayahara Kotoe, Tanabe N, Koshi R, Nakajima A, Kawato T, Maeno M, Shimizu N, Motoyoshi M
- Journal Title
  
  Medical Science Monitor
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K12022
[Journal Article] Continuous application of compressive force induces fusion of osteoclast-like RAW264.7 cells via upregulation of RANK and downregulation of LGR42018
- Author(s)
  Matsuike R, Tanaka H, Nakai K, Kanda M, Nagasaki M, Murakami F, Shibata C, Mayahara K, Nakajima A, Tanabe N, Kawato T, Maeno M, Shimizu N
- Journal Title
  
  Life Science
  
  Volume: 201 Pages: 30-36
- DOI
  10.1016/j.lfs.2018.03.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K12022
[Journal Article] IL-17A suppresses the expression of bone resorption-related proteinases and osteoclast differentiation via IL-17RA or IL-17RC receptors in RAW264.7 cells.2010
- Author(s)
  Kitami S, Tanaka H, Kawato T, Tanabe N, Katono-Tani T, Zhang F, Suzuki N, Yonehara Y, Maeno M
- Journal Title
  
  Biochimie
  
  Volume: 92 Pages: 398-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792132
[Journal Article] IL-17A suppresses the expression of bone resorption-related proteinases and osteoclast differentiation via IL-17RA or IL-17RC receptors in RAW264.7 cells.2010
- Author(s)
  Kitami S, Tanaka H, Kawato T, Tanabe N, Katono-Tani T, Zhang F, Suzuki N, Yonehara Y, Maeno M
- Journal Title
  
  Biochimie 92
  
  Pages: 398-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792132
[Journal Article] Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts.2010
- Author(s)
  Zhang F, Tanaka H, Kawato T, Kitami S, Nakai K, Motohashi M, Suzuki N, Wang C, Ochiai K, Isokawa K, Maeno M
- Journal Title
  
  Biochimie 93
  
  Pages: 296-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21792132
[Journal Article] Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinases, plasminogenactivators, and their inhibitors in human osteoblasts2009
- Author(s)
  Katono T, Tanabe N, Tanaka H, Suzuki N, Maeno M, 他5名
- Journal Title
  
  Arch Oral Biol 54(2)
  
  Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] 成人男性における歯周病と脂肪肝およびその線維化との関連性2022
- Author(s)
  森田十誉子、山崎洋治、山本高司、中井久美子、田中秀樹、尾崎愛美、川戸貴行
- Organizer
  第71回日本口腔衛生学会・総会
- Data Source
  KAKENHI-PROJECT-20K10298
[Presentation] 炎症性サイトカインが脂肪細胞の血管新生因子の発現に及ぼす影響2019
- Author(s)
  柴田知佳，中井久美子，柏木　勝，小口久雄，唐鎌史行，北見　聡，田中秀樹，前野正夫，川戸貴行
- Organizer
  第68回日本口腔衛生学会・総会
- Data Source
  KAKENHI-PROJECT-17K12022
[Presentation] 持続的な圧迫力は破骨細胞の分化を促進する2018
- Author(s)
  松生理恵子，田中秀樹，中井久美子，岡　仁，原田修成，飯田隆文，前野正夫，清水典佳，川戸貴行
- Organizer
  第67回日本口腔衛生学会・総会
- Data Source
  KAKENHI-PROJECT-17K12022
[Presentation] Compressive force induces fusion of osteoclast-like RAW264.7 cells2018
- Author(s)
  Matsuike R, Tanaka H, Nakai K, Mayahara K, Kawato T, Maeno M, Shimizu N
- Organizer
  96th General Session & Exhibition of IADR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K12022
[Presentation] 酪酸は骨芽細胞の分化を抑制しPGE_2産生を促進する2010
- Author(s)
  飯田隆文, 田中秀樹, 川戸貴行, 前野正夫
- Organizer
  第59回日本口腔衛生学会
- Place of Presentation
  新潟
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21792132
[Presentation] 酪酸は骨芽細胞の分化を抑制しPGE2産生を促進する.口腔衛生会誌60(4):4172010
- Author(s)
  飯田隆文, 田中秀樹, 川戸貴行, 田邉奈津子, 神尾宣昌, 北見聡, 桑原亜貴子, 中井久美子, 前野正夫
- Organizer
  第59回日本口腔衛生学会・総会
- Place of Presentation
  朱鷺メッセ,新潟県
- Data Source
  KAKENHI-PROJECT-21792132
[Presentation] IL-17A suppresses proteinase expression and osteoclast differentiation in RAW264.7 cells. 47542010
- Author(s)
  Kitami S, Tanaka H, Kawato T, Tanabe N, Motohashi M, Maeno M
- Organizer
  88^<th> General Session & Exhibition of IADR
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21792132
[Presentation] Butyric acid induces Coxs and PGE2 production in ROS17/2.8 cells. 17252010
- Author(s)
  Iida T, Kawato T, Tanaka H, Katono-Tani T, Kuwabara A, Tanabe N, Kawaguchi T, Maeno M
- Organizer
  88^<th> General Session & Exhibition of IADR
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21792132
[Presentation] 酪酸は骨芽細胞のCOX-1およびCOX-2発現増加を介してPGE2産生を促進する.2010
- Author(s)
  飯田隆文, 田中秀樹, 上遠野(谷)朋子, 桑原亜貴子, 川戸貴行, 田邊奈津子, 前野正夫, 川口隆彦
- Organizer
  プログラム:30,日本歯科保存学会2010年度春季学術大会(第132回)
- Place of Presentation
  崇城大学市民ホール,熊本県
- Data Source
  KAKENHI-PROJECT-21792132
[Presentation] ニコチンは破骨細胞のERKを介して酸産生酵素の発現を増加する.2008
- Author(s)
  田中秀樹
- Organizer
  第57回日本口腔衛生学会・総会
- Place of Presentation
  大宮ソニックシティ, 大宮
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] ニコチンは破骨細胞の炭酸脱水酵素II型の発現を増加させる2008
- Author(s)
  田中秀樹, 他4名
- Organizer
  第17回硬組織再生生物学会学術大会・総会
- Place of Presentation
  徳島
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] ニコチンは破骨細胞の炭酸脱水酵素II型の発現を増加させる.2008
- Author(s)
  田中秀樹
- Organizer
  第17回硬組織再生生物学会学術大会・総会
- Place of Presentation
  徳島文理大学, 徳島
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] ニコチンは破骨細胞のERKを介して酸産生酵素の発現を増加する2008
- Author(s)
  田中秀樹, 他6名
- Organizer
  第57回日本口腔衛生学会
- Place of Presentation
  大宮
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] ニコチンは破骨細胞の炭酸脱水酵素II型とカテプシンKの発現を増加させる2007
- Author(s)
  田中秀樹
- Organizer
  第56回日本口腔衛生学会・総会
- Place of Presentation
  タワーホール船堀,東京
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cells by increasing macrophage colony-stimulating fator and prostaglandin E_2 production by osteoblasts.2007
- Author(s)
  Hideki Tanaka
- Organizer
  29th ASBMR Annual Meeting
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2007-09-18
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] ニコチンは破骨細胞の炭酸脱水酵素II型とカテプシンKの発現を増加させる2007
- Author(s)
  田中秀樹
- Organizer
  第56回日本口腔衛生学会・総会
- Place of Presentation
  東京船堀
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18890203
[Presentation] Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cells by increasing macrophage colony-stimulating factor and prostaglandin E2 production by osteoblasts.2007
- Author(s)
  Tanaka Hideki
- Organizer
  29th ASBMR Annual Meeting
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2007-09-16
- Data Source
  KAKENHI-PROJECT-18890203
[Presentation] ニコチンは破骨細胞の炭酸脱水酵素II型とカテプシンKの発現を増加させる2007
- Author(s)
  田中秀樹, 他7名
- Organizer
  第56回日本口腔衛生学会総会
- Place of Presentation
  東京
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19592182
[Presentation] Nicotine and lipopolysaccharide stimulate the formation of osteoclast-like cellsby increasing macrophage colony-stimulating factor and prostaglandin E2 production by osteoblasts2007
- Author(s)
  Tanaka H, 他7名
- Organizer
  JBMR 22, 29th ASBMR Annual Meeting
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2007-09-18
- Data Source
  KAKENHI-PROJECT-19592182

1. KAWATO Takayuki (50386075)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. 中井久美子 (50736725)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. MAENO Masao (60147618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. TANABE Natsuko (10409097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 森田十誉子 (00597247)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. SUZUKI Naoto (10226532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 尾崎愛美 (10867930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 山本高司 (60868529)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 小菅康弘 (70383726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tanaka Hideki 田中 秀樹

田中 秀樹 タナカ ヒデキ

TANAKA Hideki 田中 秀樹

Research Projects

Research Products

Co-Researchers

セルフケアとプロフェッショナルケアによる歯周病予防の効果を高めるための基礎研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effects of periodontal disease on hepatic steatosis -an epidemiological and cell biological study-

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell Biology and epidemiological studies of non-obese metabolic syndrome prevention focused on periodontal disease study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of nicotine on the signal transduction in osteoclast precursorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of molecular mechanism that deteriorates periodontitis with alveolar bone resorption by nicotine and lipopolysaccharide.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ニコチンとLPSが破骨細胞前駆細胞の機能発現に及ぼす影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of dental health intervention on cardiovascular metabolic risk: a pilot study of Japanese Adults2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Periodontitis and Toothbrushing Frequency on Obesity Onset: A Cohort Study.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Continuous compressive force induces the differentiation of osteoclasts with high levels of inorganic dissolution.2019

Author(s)

Journal Title

Data Source

[Journal Article] Continuous application of compressive force induces fusion of osteoclast-like RAW264.7 cells via upregulation of RANK and downregulation of LGR42018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-17A suppresses the expression of bone resorption-related proteinases and osteoclast differentiation via IL-17RA or IL-17RC receptors in RAW264.7 cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] IL-17A suppresses the expression of bone resorption-related proteinases and osteoclast differentiation via IL-17RA or IL-17RC receptors in RAW264.7 cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts.2010

Author(s)

Journal Title

Data Source

[Journal Article] Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinases, plasminogenactivators, and their inhibitors in human osteoblasts2009

Author(s)

Journal Title

Data Source

[Presentation] 成人男性における歯周病と脂肪肝およびその線維化との関連性2022

Author(s)

Organizer

Tanaka Hideki 田中秀樹

田中秀樹タナカヒデキ

TANAKA Hideki 田中秀樹