Takaso Masashi 高相晶士

… Alternative Names

TAKASO Masashi 高相晶士

高相昌士タカソウマサシ

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Researcher Number	90439117
Other IDs	https://orcid.org/0000-0003-3193-8643
Affiliation (Current)	2025: 北里大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 北里大学, 医学部, 教授 2013 – 2016: 北里大学, 医学部, 教授 2010: 北里大学, 医学部附属病院, 教授 2009: 北里大学, 医学部, 講師 2009: 北里大学, 医学部附属病院, 准教授
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator コラーゲン結合型成長因子 / 性差 / 変形性関節症 / MAIT / ペプチド / 末梢神経障害 / マクロファージ / RAG2 KO / M2マクロファージ / T細胞サブセット … More / CD8 / T細胞 / 絞扼性神経障害 / 非炎症性 / 変形性膝関節症 / ゲノム編集 / 非古典経路 / 古典経路 / TGF-β / 血管内皮成長因子 / Apelin / 神経ペプチド / 疼痛 / 血管内皮増殖因子 / コラーゲン材料 / 細菌 / 再生医学 / 運動器再生 / コラーゲン結合ドメイン / コラーゲン / 塩基性線維芽細胞増殖因子 / 細菌コラゲナーゼ / 運動器再生医療 / 機能性人工骨膜 / 人工骨膜組織 / 細胞積層技術 / 間葉系幹細胞 / 人工骨膜 … More Except Principal Investigator 腰痛 / サイトカイン / 細胞内シグナル / 椎間板 / 治療 / 筋量 / サルコペニア / 骨粗鬆症 / 筋肉 / ロコモティブシンドローム / 感覚神経 / 後根神経節 / 伝達 / 脊椎 / 疼痛 / 神経 / シグナル / 細胞 / グリア Less

MAIT細胞に着眼した変形性関節症病態の性差の解明Principal Investigator
- Principal Investigator
  
  高相晶士
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Identification of T Cell Subsets Involved in Constriction Nerve Injury and Development of Therapeutic Methods Using NeuropeptidesPrincipal Investigator
- Principal Investigator
  
  Takaso Masashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Proposal of a definition of sarcopenia based on trunk muscles and a study on the correlation between sarcopenia and clinical symptoms such as low back pain
- Principal Investigator
  
  Ohtori Seiji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Chiba University
Inflammatory-independent pain mechanism via to VEGF/neuropeptide axisPrincipal Investigator
- Principal Investigator
  
  Takaso Masashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kitasato University
Musculoskeletal regeneration using Growth factor-anchored materialsPrincipal Investigator
- Principal Investigator
  
  Masashi Takaso
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kitasato University
Development of novel fracture healing methods using artificical perioteum and collagen-binding growth factor containing a collagen-binding domain from Clostridium histolyticum collagenasePrincipal Investigator
- Principal Investigator
  
  TAKASO Masashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Kitasato University
Patho-mechanism of discogenic low back pain
- Principal Investigator
  
  TAKAHASHI Kazuhisa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Chiba University
Patho-mechanism of transmission of low back pain
- Principal Investigator
  
  OHTORI Seiji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Chiba University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2011 2010 Other

All Journal Article Presentation Patent

[Journal Article] Nerve decompression surgery suppresses TNF-a; expression and T cell infiltration in a rat sciatic nerve chronic constriction injury model2022
- Author(s)
  Mukai M, Uchida K, Inoue G, Satoh M, Miyagi M, Yokozeki Y, Hirosawa N, Matsuura Y, Ohtori S, Takaso M
- Journal Title
  
  J Orthop Res
  
  Volume: in press Issue: 11 Pages: 0-0
- DOI
  10.1002/jor.25280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09011, KAKENHI-PROJECT-20K09415, KAKENHI-PROJECT-21K09308, KAKENHI-PROJECT-21K20961, KAKENHI-PROJECT-22K08679
[Journal Article] Expression and regulation of macrophage-inducible C-type lectin in human synovial macrophages2020
- Author(s)
  Moriya M, Uchida K, Takano S, Iwase D, Inoue G, Mukai M, Tazawa R, Aikawa J, Sekiguchi H, Takaso M
- Journal Title
  
  Cent Eur J Immunol
  
  Volume: 45 Issue: 4 Pages: 377-381
- DOI
  10.5114/ceji.2020.103411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09119
[Journal Article] Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee2020
- Author(s)
  Takata K, Uchida K, Mukai M, Takano S, Aikawa J, Iwase D, Sekiguchi H, Miyagi M, Inoue G, Takaso M
- Journal Title
  
  Diabetes Metab Syndr Obes
  
  Volume: 13 Pages: 1491-1497
- DOI
  10.2147/dmso.s253147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18073, KAKENHI-PROJECT-18K09119
[Journal Article] Vascular endothelial growth factor is regulated by the canonical and non-canonical transforming growth factor-β pathway in synovial fibroblasts derived from osteoarthritis patients2019
- Author(s)
  Takano S, Uchida K, Shoji S, Itakura M, Iwase D, Aikawa J, Mukai M, Sekiguchi H, Inoue G, Takaso M.
- Journal Title
  
  Biomed Res Int
  
  Volume: - Pages: 6959056-6959056
- DOI
  10.1155/2019/6959056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09119, KAKENHI-PROJECT-19K24037
[Journal Article] Vascular endothelial growth factor expression and their action in the synovial membranes of patients with painful knee osteoarthritis2018
- Author(s)
  Takano S, Uchida K, Inoue G, Matsumoto T, Aikawa J, Iwase D, Mukai M, Miyagi M, Takaso M
- Journal Title
  
  BMC Musculoskelet Disord
  
  Volume: 19 Issue: 1 Pages: 204-204
- DOI
  10.1186/s12891-018-2127-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09119
[Journal Article] Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia2018
- Author(s)
  Mukai M, Uchida K, Takano S, Iwase D, Aikawa J, Inoue G, Miyagi M, Takaso M
- Journal Title
  
  Lipid in health and disease
  
  Volume: 17 Issue: 1 Pages: 137-137
- DOI
  10.1186/s12944-018-0792-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09119
[Journal Article] Regulation of calcitonin gene-related peptide expression through the COX-2/mPGES-1/PGE2 pathway in the infrapatellar fat pad in knee osteoarthritis2018
- Author(s)
  Aikawa J, Uchida K, Takano S, Inoue G, Iwase D, Miyagi M, Mukai M, Shoji S, Sekiguchi H, Takaso M
- Journal Title
  
  Lipid in health and disease
  
  Volume: 17 Issue: 1 Pages: 215-215
- DOI
  10.1186/s12944-018-0864-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09119
[Journal Article] Oriented collagen tubes combined with basic fibroblast growth factor promote peripheral nerve regeneration in a 15 mm sciatic nerve defect rat model2017
- Author(s)
  Fujimaki H, Uchida K, Inoue G, Miyagi M, Nemoto N, Saku T, Isobe Y, Inage K, Matsushita O, Yagishita S, Sato J, Takano S, Sakuma Y, Ohtori S, Takahashi K, Takaso M.
- Journal Title
  
  J Biomed Mater Res A
  
  Volume: 105 Issue: 1 Pages: 8-14
- DOI
  10.1002/jbm.a.35866
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293341, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-15K20015
[Journal Article] Effect of Freeze-Dried Allograft Bone with Human Basic Fibroblast Growth Factor Containing a Collagen-Binding Domain From Clostridium Histolyticum Collagenase on Bone Formation After Lumbar Posterolateral Fusion Surgery in Rats2017
- Author(s)
  Inoue G, Uchida K, Matsushita O, Fujimaki H, Saito W, Miyagi M, Sekiguchi H, Nishi N, Ohtori S, Yogoro M, Takaso M.
- Journal Title
  
  Spine
  
  Volume: 印刷中 Issue: 17 Pages: 995-1001
- DOI
  10.1097/brs.0000000000002074
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293341, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861209, KAKENHI-PROJECT-15K20015, KAKENHI-PROJECT-17K10982, KAKENHI-PROJECT-17K16701
[Journal Article] Acceleration of bone formation during fracture healing by poly(pro-hyp-gly)10 and basic fibroblast growth factor containing polycystic kidney disease and collagen-binding domains from Clostridium histolyticum collagenase2016
- Author(s)
  Sekiguchi H, Uchida K, Inoue G, Matsushita O, Saito W, Aikawa J, Tanaka K, Fujimaki H, Miyagi M, Takaso M.
- Journal Title
  
  J Biomed Mater Res A
  
  Volume: 104 Issue: 6 Pages: 1372-1378
- DOI
  10.1002/jbm.a.35670
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K20015, KAKENHI-PROJECT-26861209, KAKENHI-PROJECT-26861210, KAKENHI-PROJECT-26293341, KAKENHI-PROJECT-26460527
[Journal Article] Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen binding domain fusion protein combined with allogenic demineralized bone powder.2015
- Author(s)
  Saito W, Uchida K, Matsushita O, Inoue G, Sekiguchi H, Aikawa J, Fujimaki H, Takaso M.
- Journal Title
  
  J Orthop Surg Res
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293341
[Journal Article] Enhancement of periosteal bone formation by basic fibroblast-derived growth factor containing polycystic kidney disease and collagen-binding domains from Clostridium histolyticum collagenase．2015
- Author(s)
  Uchida K, Matsushita O, Nishi N, Inoue G, Horikawa K, Takaso M. ．
- Journal Title
  
  J Tissue Eng Regen Med
  
  Volume: in press Issue: 4 Pages: 1165-1172
- DOI
  10.1002/term.2019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26293341
[Journal Article] CD11c+ macrophages and levels of TNF-α and MMP-3 are increased in synovial and adipose tissues of osteoarthritic mice with hyperlipidemia.2015
- Author(s)
  Uchida K, Satoh M, Inoue G, Onuma K, Miyagi M, Iwabuchi K, Takaso M.
- Journal Title
  
  Exp Clin Immunol
  
  Volume: in press Issue: 3 Pages: 551-559
- DOI
  10.1111/cei.12607
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-25870708, KAKENHI-PROJECT-25460502
[Journal Article] Acceleration of callus formation during fracture healing using basic fibroblast growth factor-kidney disease domain-collagen binding domain fusion protein combined with allogenic demineralized bone powder.2015
- Author(s)
  Saito W, Uchida K, Matsushita O, Inoue G, Sekiguchi H, Aikawa J, Fujimaki H, Takaso M.
- Journal Title
  
  J Orthop Surg Res
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670659
[Journal Article] Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase.2014
- Author(s)
  Uchida K, Matsushita O, Naruse K, Mima T, Nishi N, Hattori S, Ogura T, Inoue G, Tanaka K, Takaso M.
- Journal Title
  
  J Biomed Mater Res A.
  
  Volume: 102 Issue: 6 Pages: 1737-1743
- DOI
  10.1002/jbm.a.34841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-23790483, KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
[Journal Article] Risk factors for L5-S1 disk height reduction after lumbar posterolateral floating fusion surgery.2014
- Author(s)
  Inoue G, Takaso M, Miyagi M, Kamoda H, Ishikawa T, Nakazawa T, Imura T, Ueno M, Saito W, Uchida K, Toyone T, Takahashi K, Ohtori S.
- Journal Title
  
  J Spinal Disord Tech
  
  Volume: in press Issue: 5 Pages: E187-E192
- DOI
  10.1097/bsd.0000000000000088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26861210
[Journal Article] Teriparatide increases the insertional torque of pedicle screws during fusion surgery in patients with postmenopausal osteoporosis.2014
- Author(s)
  Inoue G, Ueno M, Nakazawa T, Imura T, Saito W, Uchida K, Ohtori S, Toyone T, Takahira N, Takaso M.
- Journal Title
  
  J Neurosurg Spine
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670659
[Journal Article] Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase2013
- Author(s)
  Saito W, Uchida K, Ueno M, MatsushitaO, Inoue G, Nishi N, Ogura T, Hattori S, Fujimaki H, Tanaka K, Takaso M
- Journal Title
  
  J Biomed Mater Res A
  
  Volume: in press Issue: 9 Pages: 3049-3055
- DOI
  10.1002/jbm.a.34974
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590516, KAKENHI-PROJECT-24791560, KAKENHI-PROJECT-25670659, KAKENHI-PROJECT-26460527, KAKENHI-PROJECT-26861210
[Journal Article] Triclosan-coated sutures reduce wound infections after spinal surgery: a retrospective, non-randomized, clinical study2013
- Author(s)
  Ueno M, Saito W, Yamagata M, Imura T, Inoue G, Nakazawa T, Takahira N, Uchida K, Fukahori N, Smimomura K, Takaso M.
- Journal Title
  
  Spine J
  
  Volume: - Issue: 5 Pages: 933-938
- DOI
  10.1016/j.spinee.2013.06.046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670659
[Journal Article] Direct Application of the Tumor Necrosis Factor-α Inhibitor, Etanercept, Into a Punctured Intervertebral Disc Decreases Calcitonin Gene-Related Peptide Expression in Rat Dorsal Root Ganglion Neurons2011
- Author(s)
  Horii M, Orita S, Nagata M, Takaso M, Yamauchi K, Yamashita M, Inoue G, Eguchi Y, Ochiai N, Kishida S, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Kuniyoshi K, Suzuki M, Nakamura J, Toyone T, Takahashi K, Ohtori S
- Journal Title
  
  Spine
  
  Volume: 36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591891
[Journal Article] Less invasive and less technically demanding decompressive procedure for lumbar spinal stenosis-appropriate for general orthopaedic surgeons?2011
- Author(s)
  Takaso M, Nakazawa T, Imura T, Okada T, Fukushima K, Ueno M, Saito W, Shintani R, Sakagami H, Takahashi K, Yamazaki M, Ohtori S, Kotani T
- Journal Title
  
  Int Orthop. 35
  
  Pages: 67-73
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Low back pain after lumbar discectomy in patients showing endplate modic type 1 change.2010
- Author(s)
  Ohtori S, Yamashita M, Yamauchi K, Inoue G, Koshi T, Suzuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Nakamura J, Takahashi K
- Journal Title
  
  Spine. 35
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Can the caudal extent of fusion in the surgical treatment of scoliosis in Duchenne muscular dystrophy be stopped at lumbar 5?2010
- Author(s)
  Takaso M, Nakazawa T, Imura T, Ueno M, Saito W, Shintani R, Takahashi K, Yamazaki M, Ohtori S, Okamoto M, Masaki T, Okamoto H, Okutomi T, Ishii K, Ueda Y
- Journal Title
  
  Eur Spine J. 19
  
  Pages: 787-96
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Change in Modic Type 1 and 2 signals after posterolateral fusion surgery.2010
- Author(s)
  Ohtori S, Yamashita M, Yamauchi K, Inoue G, Koshi T, Suzuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Kuniyoshi K, Ishikawa T, Arai G, Miyagi M, Kamoda H, Nakamura J, Aoki Y, Takahashi K
- Journal Title
  
  Spine. 35
  
  Pages: 1231-5
- NAID
  10028064843
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Surgical management of severe scoliosis with high risk pulmonary dysfunction in Duchenne muscular dystrophy : patient function, quality of life and satisfaction.2010
- Author(s)
  Takaso M, Nakazawa T, Imura T, Okada T, Fukushima K, Ueno M, Takahira N, Takahashi K, Yamazaki M, Ohtori S, Okamoto H, Okutomi T, Okamoto M, Masaki T, Uchinuma E, Sakagami H
- Journal Title
  
  Int Orthop. 34
  
  Pages: 695-702
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Existence of pyogenic spondylitis in Modic type 1 change without other signs of infection : 2-year follow-up.2010
- Author(s)
  Ohtori S, Koshi T, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Takaso M, Orita S, Eguchi Y, Ochiai N, Kishida S, Kuniyoshi K, Nakamura J, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Takahashi K
- Journal Title
  
  Eur Spine J. 19
  
  Pages: 1200-5
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Low affinity NGF receptor (p75 neurotrophin receptor) inhibitory antibody reduces pain behavior and CGRP expression in DRG in the mouse sciatic nerve crush model2010
- Author(s)
  Fukui Y, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Wakai K, Hayashi Y, Aoki Y, Takahashi K
- Journal Title
  
  J Orthop Res
  
  Volume: 28 Pages: 279-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591891
[Journal Article] Primary sensory neurons with dichotomizing axons projecting to the facet joint and the low back muscle in rats.2010
- Author(s)
  Wakai K, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Fukui Y, Hayashi Y, Aoki Y, Kuniyoshi K, Nakamura J, Ishikawa T, Arai G, Miyagi M, Kamoda H, Takahashi K
- Journal Title
  
  J Orthop Sci. 15
  
  Pages: 402-6
- NAID
  10027404211
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Direct evidence for sensory innervation of the dorsal portion of the Co5/6 coccygeal intervertebral disc in rats.2010
- Author(s)
  Orita S, Ohtori S, Taniguchi A, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Eguchi Y, Ochiai N, Kishida S, Takaso M, Aoki Y, Takahashi K, Kawakami M
- Journal Title
  
  Spine. 35
  
  Pages: 1346-52
- NAID
  10028065427
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Effect of applying p75NTR saporin to a punctured intervertebral disc on calcitonin gene-related peptide expression in rat dorsal root ganglion neurons.2010
- Author(s)
  Sugiura A, Ohtori S, Yamashita M, Yamauchi K, Inoue G, Suzuki M, Norimoto M, Orita S, Eguchi Y, Kuniyoshi K, Ochiai N, Kishida S, Takaso M, Aoki Y, Ishikawa T, Arai G, Miyagi M, Kamoda H, Nakamura J, Takahashi K
- Journal Title
  
  J Orthop Sci. 15
  
  Pages: 407-13
- NAID
  10027404233
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Two-year results for scoliosis secondary to Duchenne muscular dystrophy fused to lumbar 5 with segmental pedicle screw instrumentation.2010
- Author(s)
  Takaso M, Nakazawa T, Imura T, Okada T, Toyama M, Ueno M, Fukushima K, Saito W, Minatani A, Miyajima G, Fukuda M, Takahira N, Takahashi K, Yamazaki M, Ohtori S, Okamoto H, Okutomi T, Okamoto M, Masaki T
- Journal Title
  
  J Orthop Sci. 15
  
  Pages: 171-7
- NAID
  10027403332
- Data Source
  KAKENHI-PROJECT-20500439
[Journal Article] Evaluation of behavior and neuropeptide markers of pain in a simple, sciatic nerve-pinch pain model in rats.2010
- Author(s)
  Hirose K, Iwakura N, Orita S, Yamashita M, Inoue G, Yamauchi K, Eguchi Y, Ochiai N, Kishida S, Nakamura J, Takaso M, Ishikawa T, Arai G, Miyagi M, Kamoda H, Aoki Y, Hiwatari R, Kakizaki J, Kunishi T, Kono M, Suzuki T, Toyone T, Takahashi K, Kuniyoshi K, Ohtori S.
- Journal Title
  
  Eur Spine J. 19
  
  Pages: 1746-52
- Data Source
  KAKENHI-PROJECT-20500439
[Patent] 神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット2015
- Inventor(s)
  内田健太郎、井上玄、藤巻寿子、高相晶士、松下治
- Industrial Property Rights Holder
  内田健太郎、井上玄、藤巻寿子、高相晶士、松下治
- Industrial Property Rights Type
  特許
- Filing Date
  2015-10-16
- Overseas
- Data Source
  KAKENHI-PROJECT-26293341
[Patent] 軟骨再生用移植材料、軟骨再生用移植材料の製造方法2014
- Inventor(s)
  内田健太郎、井上玄、高相晶士他6名
- Industrial Property Rights Holder
  内田健太郎、井上玄、高相晶士他6名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-246016
- Filing Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-26293341
[Patent] 神経再生用移植材料、神経再生用移植材料の製造方法、及び神経再生用移植材料製造用キット.2014
- Inventor(s)
  内田健太郎　井上　玄、高相晶士、松下　治他8名
- Industrial Property Rights Holder
  内田健太郎　井上　玄、高相晶士、松下　治他8名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-212085
- Filing Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 絞扼性末梢神経障害モデルにおいてCD8T細胞はマクロファージの極性化に関与する2023
- Author(s)
  白澤栄樹, 内田健太郎, 井上玄, 宮城正行, 横関雄司, 柴田直弥, 小沼賢治, 向井務晃, 高相晶士
- Organizer
  第３８回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09308
[Presentation] 末梢神経障害におけるV-set and transmembrane domain containing 4の役割の検討2021
- Author(s)
  横関雄司、内田健太郎、向井務晃、迎学、井上玄、宮城正行、高相晶士
- Organizer
  第36回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-21K09308
[Presentation] 変形性膝関節症患者の滑膜組織におけるPeptide Lvの発現と疼痛への関与の検討.2020
- Author(s)
  迎　学、内田健太郎、高野昇太郎、高田研、岩瀬大、相川淳、大貫裕子、関口裕之、井上玄、高相晶士
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] 女性の変形性膝関節症患者の滑膜組織では男性に比べカルシトニン遺伝子関連ペプチド受容体RAMP1の発現が高い2020
- Author(s)
  内田健太郎、高野昇太郎、高田研、迎　学、相川　淳、岩瀬大、井上玄、高相晶士
- Organizer
  第35回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] 滑膜線維芽細胞における古典経路と非古典経路のクロストークを介したTGF-βによるVEGF制御機構2019
- Author(s)
  高野昇太郎、内田健太郎、庄司真太郎、相川淳、岩瀬大、迎学、宮城正行、関口裕之、大貫裕子、高相晶士
- Organizer
  第34回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] Transforming Growth Factor-beta Stimulates Nerve Growth Factor Production Via The Tak1/p38 Pathway In Osteoarthritic Synovium.2019
- Author(s)
  Kawakubo A, Uchida K, Takano S, Aikawa J, Iwase D, Miyagi M, Nakawaki M, Sekiguchi H, Inoue G, Takaso M.
- Organizer
  ORS 2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] ヒト滑膜組織におけるC型レクチン受容体 macrophage inducible C-type leptin の発現とその制御機構の検討2018
- Author(s)
  森谷光俊、内田健太郎、高野昇太郎、岩瀬　大、井上　玄、宮城正行、田澤諒、中脇充章、大貫裕子、高相晶士
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] 肥満を有する変形性膝関節症患者の滑膜組織におけるMast cellの増加2018
- Author(s)
  内田健太郎、高野昇太郎、岩瀬大、相川淳、迎　学、井上　玄、宮城正行、小沼賢治、齋藤　亘、高相晶士.
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] 血管内皮増殖因子は変形性膝関節症患者の非炎症性疼痛に関与する2018
- Author(s)
  高野昇太郎、内田健太郎、迎　学、岩瀬　大、相川　淳、村田幸佑、宮城正行、井上　玄、大貫裕子、高相晶士
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] HbA1c高値の変形性膝関節症患者の膝蓋下脂肪体ではTNF-alpha, IL-8が亢進している2018
- Author(s)
  迎学、内田健太郎、高野昇太郎、相川淳、岩瀬大、宮城正行、東山礼治、井上　玄、大貫裕子、高相晶士
- Organizer
  第33回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-18K09119
[Presentation] Nerve reconstruction with oriented collagen tubes combined with basic fibroblast growth factor.2017
- Author(s)
  Fujimaki H, Inoue G, Uchida K, Miyagi M, Saito W, Takaso M.
- Organizer
  43rd The International Society for the Study of the Lumbar Spine Annual Meeting
- Place of Presentation
  Sands Expo & Convention Centre (Sigapore)
- Year and Date
  2017-05-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] Acceleration Of Bone Repair During Fracture Healing By Poly(pro-hyp-gly)10 And Basic Fibroblast Growth Factor Containing Collagen-binding Domains From Clostridium Histolyticum Collagenase2017
- Author(s)
  Sekiguchi H, Uchida K, Inoue G, Saito W, Aikawa J, Fujimaki H, Nagura N, Takano S, Miyagi M Takaso M
- Organizer
  ORS 2017 Annual Meeting
- Place of Presentation
  Sandiego, USA
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 細胞配向性コラーゲンチューブによる末梢神経再生 -ナーブリッジTMとの比較検討-.2016
- Author(s)
  藤巻寿子、井上玄、内田健太郎、宮城正行、大鳥精司、高相晶士.
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 新規コラーゲン結合型線維芽細胞増殖因子による骨形成促進法の開発2016
- Author(s)
  関口裕之、内田健太郎、井上玄、相川淳、斉藤亘、宮城正行、松下治、藤巻寿子、高野昇太郎、名倉直重、高相晶士.
- Organizer
  第31回日本整形外科学会基礎学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 細胞配向性コラーゲン人工神経に塩基性線維芽細胞増殖因子を組み合わせた人工神経移植による末梢神経再生の試み2015
- Author(s)
  藤巻寿子、井上玄、内田健太郎、宮城正行、高相晶士.
- Organizer
  第8回日本運動器疼痛学会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-12-12
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] コラーゲン結合型塩基性線維芽細胞増殖因子を用いた人工神経による末梢神経再生2015
- Author(s)
  藤巻寿子、井上　玄、内田健太郎、宮城正行、相川　淳、齋藤　亘、関口裕之、高相晶士
- Organizer
  第30回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県富山市）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 細菌分子によるマトリックスアンカーリング機構を応用した骨形成促進法の開発2015
- Author(s)
  内田健太郎、松下　治、齋藤　亘、井上　玄、高相晶士
- Organizer
  第18回北里微生物アカデミー研究集会
- Place of Presentation
  北里大学（神奈川県相模原市）
- Year and Date
  2015-08-06
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 細胞配向性コラーゲン人工神経と塩基性線維芽細胞増殖因子を組み合わせた新規人工神経による末梢神経再生の試み2015
- Author(s)
  藤巻寿子、井上　玄、内田健太郎、宮城正行、高相晶士
- Organizer
  第34回日本運動器移植・再生医学研究会
- Place of Presentation
  ANAクラウンプラザホテル宇部（山口県宇部市）
- Year and Date
  2015-09-25
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] Bone powder とコラーゲン結合型線維芽細胞増殖因子による骨折後の骨形成促進効果の検討.2014
- Author(s)
  斎藤　亘、内田健太郎、井上　玄、松下　治、大貫裕子、藤巻寿子、関口裕之、相川　淳、高平尚伸、高相晶士.
- Organizer
  第33回日本運動器移植・再生医学研究会
- Place of Presentation
  第一ホテル両国（東京都墨田区）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] 脊椎手術におけるコラーゲン結合ドメインを融合した塩基性線維芽細胞増殖因子の骨形成に与える影響
- Author(s)
  井上玄、内田健太郎、上野正喜、斉藤亘、中澤俊之、井村貴之、松下治、高平尚伸、高相晶士.
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-25670659
[Presentation] Acceleration of bone formation during fracture healing by injectable collagen powder and human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase
- Author(s)
  Saito W, Uchida K, Ueno M, Matsushita O, Inoue G, Nishi N, Ogura T, Hattori S, Fujimaki H, Tanaka K, Takaso M.
- Organizer
  APASTB/JSTT Combined Scientific Meeting 2014
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2014-08-27 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26293341
[Presentation] Acceleration of periosteal bone formation by human basic fibroblast growth factor containing a collagen-binding domain from Clostridium histolyticum collagenase
- Author(s)
  Uchida K, Matsushita O, Naruse K, Inoue G, Takaso M.
- Organizer
  World Congress on Controversies, Debates & Consensus in Bone, Muscle & Joint Diseases
- Place of Presentation
  Brussels
- Data Source
  KAKENHI-PROJECT-25670659
[Presentation] コラーゲン結合性線維芽細胞増殖因子（bFGF-CBD）とコラーゲンシートの併用による同種骨移植後の骨癒合促進
- Author(s)
  上野正喜、内田健太郎、斉藤　亘、余頃瑞希、井上玄、松下治、高平尚伸、高相晶士.
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-25670659
[Presentation] Injectable コラーゲンパウダーとコラーゲン結合型線維芽細胞増殖因子による骨折後の骨形成促進効果の検討
- Author(s)
  斉藤　亘、内田健太郎、上野正喜、井上　玄、大貫裕子、松下治、高相晶士.
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-25670659
[Presentation] 線維芽細胞増殖因子アンカーリング間葉系細胞積層シートの骨形成能の検討
- Author(s)
  内田健太郎、堀川恭佑、井上玄、松下　治、斎藤亘、成瀬康治、藤巻寿子、占部憲、高相晶士.
- Organizer
  第29回日本整形外科学会基礎学術集会
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-25670659

1. OHTORI Seiji (40361430)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. UCHIDA Kentaro (50547578)

# of Collaborated Projects: 4 results

# of Collaborated Products: 40 results
3. INOUE Gen (80594209)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
4. MATSUSHITA Osamu (00209537)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
5. TAKAHASHI Kazuhisa (20179477)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. 大久保直 (10450719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 宮城正行 (90627556)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 佐藤雅 (40611843)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. MABUCHI Yo (50424172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 岩瀬大 (30406946)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. 新谷歩 (00724395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 星野雅俊 (30748637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中村博亮 (60227931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 折田純久 (60638310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 稲毛一秀 (80793629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 赤澤努 (90375808)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 廣澤直也 (10882748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松井崇 (30463582)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. INOUE Joe

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. MIMA Takehiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 高野昇太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takaso Masashi 高相 晶士

TAKASO Masashi 高相 晶士

高相 昌士 タカソウ マサシ

Research Projects

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Co-Researchers

MAIT細胞に着眼した変形性関節症病態の性差の解明Principal Investigator

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Identification of T Cell Subsets Involved in Constriction Nerve Injury and Development of Therapeutic Methods Using NeuropeptidesPrincipal Investigator

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Proposal of a definition of sarcopenia based on trunk muscles and a study on the correlation between sarcopenia and clinical symptoms such as low back pain

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Inflammatory-independent pain mechanism via to VEGF/neuropeptide axisPrincipal Investigator

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Musculoskeletal regeneration using Growth factor-anchored materialsPrincipal Investigator

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Development of novel fracture healing methods using artificical perioteum and collagen-binding growth factor containing a collagen-binding domain from Clostridium histolyticum collagenasePrincipal Investigator

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Patho-mechanism of discogenic low back pain

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Patho-mechanism of transmission of low back pain

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[Journal Article] Nerve decompression surgery suppresses TNF-a; expression and T cell infiltration in a rat sciatic nerve chronic constriction injury model2022

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[Journal Article] Expression and regulation of macrophage-inducible C-type lectin in human synovial macrophages2020

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[Journal Article] Increase in Tryptase and Its Role in the Synovial Membrane of Overweight and Obese Patients with Osteoarthritis of the Knee2020

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[Journal Article] Vascular endothelial growth factor is regulated by the canonical and non-canonical transforming growth factor-β pathway in synovial fibroblasts derived from osteoarthritis patients2019

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[Journal Article] Vascular endothelial growth factor expression and their action in the synovial membranes of patients with painful knee osteoarthritis2018

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[Journal Article] Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia2018

Takaso Masashi 高相晶士

TAKASO Masashi 高相晶士

高相昌士タカソウマサシ