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Murase Kazuyuki  村瀬 和幸

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MURASE Kazuyuki  村瀬 和幸

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Researcher Number 90444918
Affiliation (Current) 2025: 札幌医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2019 – 2023: 札幌医科大学, 医学部, 講師
2017: 札幌医科大学, 医学部, 講師
2015 – 2017: 札幌医科大学, 医学部, 助教
2009 – 2010: Sapporo Medical University, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Hematology / Gastroenterology
Except Principal Investigator
Basic Section 53010:Gastroenterology-related / Tumor diagnostics / Hematology
Keywords
Principal Investigator
標的抗が ん 治療法 / 標的抗がん治療法 / 難治性軟部肉腫 / 免疫原性細胞死 / AYA世代 / BH3 profiling / 高次元サイトメトリー法 / 高次元サイトメトリー / Treg / GVHD … More / 脂質 / 再生医学 / 癌 / 核酸 / 移植・再生医療 … More
Except Principal Investigator
膵癌 / ドラッグデリバリー / ドラッグデリバリーシステム / グライコミクス / biomarker / フコシル化 / 細胞外小胞 / 白血病幹細胞 / 骨髄間質 / 間葉系幹細胞 / エキソソーム / PCBP1 / 骨髄間質細胞 / 骨髄異形成症候群 / 白血病 / マイクロRNA / エクソソーム Less
  • Research Projects

    (7 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (16 People)
  •  AYA世代難治性軟部肉腫に対する免疫原性細胞死を利用した新規抗がん治療法の開発Principal Investigator

    • Principal Investigator
      村瀬 和幸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Sapporo Medical University
  •  Development of a Novel DDS with Tumor-Directed Anticancer Drugs for Pancreatic Cancer

    • Principal Investigator
      Kato Junji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Sapporo Medical University
  •  Development of a new targeted anticancer treatment for Adolescent and Young Adult refractory soft tissue sarcomaPrincipal Investigator

    • Principal Investigator
      Murase Kazuyuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Sapporo Medical University
  •  Development of novel cancer diagnostic method by detection of sugar chain in urine using glycomics analysis

    • Principal Investigator
      Kato Junji
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor diagnostics
    • Research Institution
      Sapporo Medical University
  •  The effect of exosomal miRNA on AML/MDS stromal cells

    • Principal Investigator
      Kobune Masayoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University
  •  Comprehensive analysis of GVHD regulated cells by high dimensional cytometry and identification of prognostic factorsPrincipal Investigator

    • Principal Investigator
      Murase Kazuyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University
  •  Development of liver cancer preventive methods using VA-Lip-siRNAPrincipal Investigator

    • Principal Investigator
      MURASE Kazuyuki
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University

All 2017 2016 2015 2014 2011 2010 2009

All Journal Article Presentation

  • [Journal Article] Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma2017

    • Author(s)
      Arihara Yohei、Takada Kohichi、Kamihara Yusuke、Hayasaka Naotaka、Nakamura Hajime、Murase Kazuyuki、Ikeda Hiroshi、Iyama Satoshi、Sato Tsutomu、Miyanishi Koji、Kobune Masayoshi、Kato Junji
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 39 Pages: 65889-65899

    • DOI

      10.18632/oncotarget.19508

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-17H03599, KAKENHI-PROJECT-15K09482
  • [Journal Article] Activated p53 with Histone Deacetylase Inhibitor Enhances L-Fucose-Mediated Drug Delivery through Induction of Fucosyltransferase 8 Expression in Hepatocellular Carcinoma Cells.2016

    • Author(s)
      Okagawa Y, Murase K, Kato J, et al
    • Journal Title

      PLoS One.

      Volume: 15 Issue: 12 Pages: e0168355-e0168355

    • DOI

      10.1371/journal.pone.0168355

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
  • [Journal Article] Narrow-Band Ultraviolet B Phototherapy Ameliorates Acute Graft-Versus-Host Disease of the Intestine by Expansion of Regulatory T Cells.2016

    • Author(s)
      Hashimoto A, Murase K, Kato J. et al
    • Journal Title

      PLoS One

      Volume: 31 Issue: 3 Pages: e0152823-e0152823

    • DOI

      10.1371/journal.pone.0152823

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461429, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670178, KAKENHI-PROJECT-26670386
  • [Journal Article] The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.2016

    • Author(s)
      Kamihara Y, Murase K, Kato J, et al
    • Journal Title

      Oncotarget

      Volume: 27 Issue: 39 Pages: 64330-64341

    • DOI

      10.18632/oncotarget.11830

    • NAID

      120006576953

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-16K07178, KAKENHI-PROJECT-16K14624
  • [Journal Article] Neurolymphomatosis of the sciatic nerve diagnosed by FDG-PET/CT2016

    • Author(s)
      Usami M, Murase K, Kato J. et al
    • Journal Title

      Rinsho Ketsueki

      Volume: 57 Issue: 1 Pages: 52-55

    • DOI

      10.11406/rinketsu.57.52

    • NAID

      130005125846

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09508
  • [Journal Article] Extracellular vesicle miR-7977 is involved in hematopoietic dysfunction of mesenchymal stromal cells via poly(rC) binding protein 1 reduction in myeloid neoplasms.2016

    • Author(s)
      Horiguchi H, Murase K, Kato J. et al
    • Journal Title

      Haematologica

      Volume: 101 Issue: 4 Pages: 437-447

    • DOI

      10.3324/haematol.2015.134932

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26670386
  • [Journal Article] A phase II trial of small-dose bortezomib, lenalidomide and dexamethasone (sVRD) as consolidation/maintenance therapy in patients with multiple myeloma.2016

    • Author(s)
      Ibata S, Murase K, Kato J, et al
    • Journal Title

      Cancer Chemother Pharmacol.

      Volume: 78 Pages: 1041-1049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09508
  • [Journal Article] Effect of duloxetine in Japanese patients with chemotherapy-induced peripheral neuropathy: a pilot randomized trial.2015

    • Author(s)
      Hirayama Y, Ishitani K, Sato Y, Iyama S, Takada K, Murase K, Kuroda H, Nagamachi Y, Konuma Y, Fujimi A, Sagawa T, Ono K, Horiguchi H, Terui T, Koike K, Kusakabe T, Sato T, Takimoto R, Kobune M, Kato J
    • Journal Title

      Int J Clin Oncol

      Volume: 20 Issue: 5 Pages: 866-871

    • DOI

      10.1007/s10147-015-0810-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09482, KAKENHI-PROJECT-15K09508, KAKENHI-PROJECT-25461430
  • [Journal Article] A dose-escalation study of oxaliplatin/capecitabine/irinotecan (XELOXIRI) and bevacizumab as a first-line therapy for patients with metastatic colorectal cancer.2015

    • Author(s)
      Sato Y, Ohnuma H, Hirakawa M, Takahashi M, Osuga T, Okagawa Y, Murase K, Takada K, Kawano Y, Iyama S, Hayashi T, Sato T, Miyanishi K, Takimoto R, Kobune M, Okita K, Mizuguchi T, Furuhata T, Hirata K, Kato J
    • Journal Title

      Cancer Chemother Pharmacol

      Volume: 75 Issue: 3 Pages: 587-597

    • DOI

      10.1007/s00280-014-2672-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-25461430, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
  • [Journal Article] BAK is a predictive and prognostic biomarker for the therapeutic effect of docetaxel treatment in patients with advanced gastric cancer.2015

    • Author(s)
      Kubo T, Murase K, Kato J. et al
    • Journal Title

      Gastric Cancer.

      Volume: 20

    • NAID

      40020881713

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K09508
  • [Journal Article] RNAi-mediated gene silencing of ST6GalNAc I suppresses the metastatic potential in gastric cancer cells2014

    • Author(s)
      Tamura F, Sato Y, Hirakawa M, Yoshida M, Ono M, Osuga T, Okagawa Y, Uemura N, Arihara Y, Murase K, Kawano Y, Iyama S, Takada K, Hayashi T, Sato T, Miyanishi K, Kobune M, Takimoto R, Kato J.
    • Journal Title

      Gastric Cancer

      Volume: 23 Issue: 1 Pages: 85-97

    • DOI

      10.1007/s10120-014-0454-z

    • NAID

      40020700032

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590921, KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-26461037, KAKENHI-PROJECT-26670386, KAKENHI-PROJECT-15K09508
  • [Journal Article] Tuberculous pleuritis with onset of refractory pleural effusion after chemoradiotherapy for esophageal cancer.2011

    • Author(s)
      Hirakawa M, Sato Y, Ohnuma H, Sagawa T, Ishiwatari H, Murase K, Iyama S, Hayashi T, Sato T, Miyanishi K, Kobune M, Takimoto R, Kato J.
    • Journal Title

      Nippon Shokakibyo Gakkai Zasshi 108(2)

      Pages: 231-237

    • NAID

      10029388119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Two cases of myelodysplastic syndrome associated with pyoderma gangrenosum.2011

    • Author(s)
      Murase K, Sato T, Takimoto R, Kobune M, Kato J.
    • Journal Title

      Rinsho zasshi Naika. In press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Endoscopic findings of enteropathy-type T-cell lymphoma by double-balloon enteroscopy and capsule endoscopy.2010

    • Author(s)
      Sato Y, Murase K
    • Journal Title

      Dig Endosc

      Volume: 22 Pages: 243-5

    • NAID

      10028187103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Endoscopic findings of enteropathy-type T-cell lymphoma by double-balloon enteroscopy and capsule endoscopy.2010

    • Author(s)
      Sato Y, Ono M, Sagawa T, Takimoto R, Hirakawa M, Ohnuma H, Sato T, Iyama S, Murase K, Miyanishi K, Kobune M, Kato J.
    • Journal Title

      Dig Endosc 22(3)

      Pages: 243-245

    • NAID

      10028187103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Evaluation of the efficacy of liposomal amphotericin B.2010

    • Author(s)
      Iyama S, Murase K
    • Journal Title

      Kansenshogaku Zasshi

      Volume: 84 Pages: 182-6

    • NAID

      10026893557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Evaluation of the efficacy of liposomal amphotericin B.2010

    • Author(s)
      Iyama S, Murase K, Sato T, Kikuchi S, Sato Y, Kobune M, Takimoto R, Kato J.
    • Journal Title

      Kansenshogaku Zasshi 84(2)

      Pages: 182-186

    • NAID

      10026893557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Therapeutic results in patients with biphenotypic acute leukemia at Sapporo Medical University Hospital.2010

    • Author(s)
      Murase K, Kato J.
    • Journal Title

      Gan To Kagaku Ryoho

      Volume: 37 Pages: 2011-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Therapeutic results in patients with biphenotypic acute leukemia at Sapporo Medical University Hospital.2010

    • Author(s)
      Murase K, Iyama S, Sato T, Takimoto R, Kobune M, Kato J.
    • Journal Title

      Gan To Kagaku Ryoho 37(10)

      Pages: 2011-2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Drug resistance is dramatically restored by hedgehog inhibitors in CD34^+ leukemic cells.2009

    • Author(s)
      Kobune M, Takimoto R, Murase K, Iyama S, Sato T, Kikuchi S, Kawano Y, Miyanishi K, Sato Y, Niitsu Y, Kato J.
    • Journal Title

      Cancer Sci 100(5)

      Pages: 948-955

    • NAID

      10025145994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Journal Article] Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.2009

    • Author(s)
      Kobune M, Murase K, et al
    • Journal Title

      Cancer science 100(5)

      Pages: 948-955

    • NAID

      10025145994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790674
  • [Presentation] Exosomal microRNAs in bone marrow cavity induce stromal dysfunction in AML/MDS2015

    • Author(s)
      Hiroto Horiguchi, Masayoshi Kobune, Shohei Kikuchi, Kazuyuki Murase, Satoshi Iyama, Kohichi Takada, Tsutomu Sato, Yasushi Sato1), Koji Miyanishi1), Rishu Takimoto, Hiroyuki Kuroda, Masahiro Maeda, Junji Kato
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県金沢市 ホテル日航金沢
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K09482
  • [Presentation] Ex vivo production of mature erythroblasts using coculture with cord blood medical human stromal cells2010

    • Author(s)
      菊地尚平、村瀬和幸
    • Organizer
      第72回日本血液学会学術集会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-09-24
    • Data Source
      KAKENHI-PROJECT-21790674
  • 1.  Kato Junji (20244345)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 2.  高田 弘一 (90398321)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 3.  Kobune Masayoshi (90336389)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  佐藤 勉 (40404602)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  堀口 拓人 (70634674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  松野 鉄平 (60774221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  大須賀 崇裕 (40619714)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  濱口 孝太 (50866613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  宮西 浩嗣 (60372819)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  在原 洋平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  佐藤 康史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  瀧本 理修
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  平川 昌宏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  水口 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  佐藤 昇志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  平田 公一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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