MIYAUCHI Yoshiteru 宮内芳輝

Researcher Number	90445411
Affiliation (based on the past Project Information) *help	2013: 慶應義塾大学, 医学部, 共同研究員 2012: 慶應義塾大学, 医学部, 研究員 2011: 慶應義塾大学, 医学部, 特任助教 2009 – 2010: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery
Keywords	Principal Investigator 破骨細胞 / 転写因子 / 骨代謝 / 骨粗鬆症 / 転写制御 / 整形外科 / 軟骨代謝学 / 骨

Regulation of osteoclastogenesis by transcriptional repressor Blimp1 via epigenetic regulationPrincipal Investigator
- Principal Investigator
  
  MIYAUCHI Yoshiteru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
Regulation of osteoclastogenesis by transcriptional repressorsPrincipal Investigator
- Principal Investigator
  
  MIYAUCHI Yoshiteru
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University

All 2013 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.2013
- Author(s)
  Miyauchi Y, Sato Y, Kobayashi T, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Miyamoto K, Tando T, Morioka H, Matsumoto M, Chambon P, Johnson RS, Kato S, Toyama Y, Miyamoto T.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 110 Issue: 41 Pages: 16568-16573
- DOI
  10.1073/pnas.1308755110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-25861341
[Journal Article] An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion2012
- Author(s)
  Miyamoto H, Katsuyama E, Miyauchi Y, Hoshi H, Miyamoto K, Sato Y, Kobayashi T, Iwasaki R, Yoshida S, Mori T, Kanagawa H, Fujie A, Hao W, Morioka H, Matsumoto M, Toyama Y, Miyamoto T
- Journal Title
  
  J Biol Chem
  
  Volume: vol. 287 Issue: 39 Pages: 32479-84
- DOI
  10.1074/jbc.m112.358226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24791561
[Journal Article] Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis2012
- Author(s)
  Hoshi H, Hao W, Fujita Y, Funayama A, Miyauchi Y, Hashimoto K, Miyamoto K, (他21名)
- Journal Title
  
  J. Bone Miner Res
  
  Volume: 27(9) Issue: 9 Pages: 2015-2023
- DOI
  10.1002/jbmr.1634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300257, KAKENHI-PROJECT-23390217, KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24500882, KAKENHI-PROJECT-24570151, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24651055, KAKENHI-PROJECT-24659395, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] PDGFBB promotes PDGFRα-positive cell migration into artificial bone in vivo.2012
- Author(s)
  Yoshida S, Iwasaki R, Kawana H, Miyauchi Y, Hoshi H, Miyamoto H, Mori T, Kanagawa H et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 421 Issue: 4 Pages: 785-789
- DOI
  10.1016/j.bbrc.2012.04.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] Neovascular niche for human myeloma cells in immunodeficient mouse bone.2012
- Author(s)
  Iriuchishima H, Takubo K, Miyakawa Y, Nakamura-Ishizu A, Miyauchi Y, Fujita N, Miyamoto K, Miyamoto T, Ikeda E, Kizaki M, Nojima Y, Suda T.
- Journal Title
  
  PLoS One.
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231
[Journal Article] An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion.2012
- Author(s)
  Miyamoto H, Katsuyama E, Miyauchi Y, Hoshi H, Miyamoto K, Sato Y, Kobayashi T, Iwasaki R et al.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 32478-32484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231
[Journal Article] Conditional inactivation of Blimp1 in adult mice promotes increased bone mass.2012
- Author(s)
  Miyauchi Y, Miyamoto H, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W et al.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 34 Pages: 28508-28517
- DOI
  10.1074/jbc.m112.356634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24791561
[Journal Article] In vivo behavior of multiple myeloma cells and their niche in immunodeficient mice2012
- Author(s)
  Iriuchishima H, Kizaki M, et al
- Journal Title
  
  PLoS ONE
  
  Volume: 7(2) Issue: 2 Pages: e30557-e30557
- DOI
  10.1371/journal.pone.0030557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591219, KAKENHI-PROJECT-21689040, KAKENHI-PROJECT-22591049, KAKENHI-PUBLICLY-23118527, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-23689049, KAKENHI-PROJECT-24591409
[Journal Article] OC-STAMP and DC-STAMP cooperatively modulate cell-cell fusion to form osteoclasts and foreign body giant cells2012
- Author(s)
  Miyamoto H, et al
- Journal Title
  
  J Bone Miner Res
  
  Volume: (In press) Issue: 6 Pages: 1289-1297
- DOI
  10.1002/jbmr.1575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689040, KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] Matrix metalloproteinase 13 in the ligamentum flavum from lumbar spinal canal stenosis patients with and without diabetes mellitus.2011
- Author(s)
  Cui G, Watanabe K, Miyauchi Y, Hosogane N, Tsuji T, Ishii K, Nakamura M, Toyama Y, Chiba K, Miyamoto T, Matsumoto M.
- Journal Title
  
  J Orthop Sci.
  
  Volume: 16 Pages: 785-790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231
[Journal Article] The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix.2011
- Author(s)
  Tohmonda T, Miyauchi Y, Ghosh R, Yoda M, Uchikawa S, Takito J, Morioka H, Nakamura M, Iwawaki T, Chiba K, Toyama Y, Urano F, Horiuchi K.
- Journal Title
  
  EMBO Rep.
  
  Volume: 12 Pages: 451-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231
[Journal Article] Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization.2011
- Author(s)
  Miyamoto K, Yoshida S, Kawasumi M, Hashimoto K, Kimura T, Sato Y, Kobayashi T, Miyauchi Y, Morioka H, Chiba K, Kobayashi T, Yasuda H, Penninger JM, Toyama Y, Suda T, Miyamoto T.
- Journal Title
  
  J Exp Med.
  
  Volume: 208 Pages: 2175-2181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231
[Journal Article] Suppressive effects for osteoclastogenesis regulated by RANKL signal.2011
- Author(s)
  Miyauchi Y, Miyamoto T.
- Journal Title
  
  Clin Calcium.
  
  Volume: 21 Pages: 1141-1147
- Data Source
  KAKENHI-PROJECT-23592231
[Journal Article] Osteoclasts are dispensable for haematopoietic stem cell maintenance and mobilization2011
- Author(s)
  Miyamoto K, et al
- Journal Title
  
  J Exp Med
  
  Volume: 208 Issue: 11 Pages: 2175-2181
- DOI
  10.1084/jem.20101890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689040, KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130004, KAKENHI-PROJECT-23249053, KAKENHI-PROJECT-23590573, KAKENHI-PROJECT-23592231
[Journal Article] The Blimpl-Bcl6 axis is critical to regulate osteoclast differentiation and bone metabolism.2010
- Author(s)
  Miyauchi, Y., et al.
- Journal Title
  
  J.Exp.Med.
  
  Volume: 207 Pages: 751-762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791410
[Journal Article] The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis2010
- Author(s)
  Yoshiteru Miyauchi, Ken Ninomiya, Hiroya Miyamoto, Akemi Sakamoto, Ryotaro Iwasaki, Hiroko Hoshi, Kana Miyamoto, Wu Hao, Shigeyuki Yoshida, Hideo Morioka, Kazuhiro Chiba, Shigeaki Kato, Takeshi Tokuhisa, Mitinori Saitou, Yoshiaki Toyama, Toshio Suda, Takeshi Miyamoto
- Journal Title
  
  Journal of Experimental Medicine 207
  
  Pages: 751-762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791410
[Journal Article] Oncogenic nucleoporin CAN/Nup214 interacts with vitamin D receptor and modulates its function.2009
- Author(s)
  Miyauchi, Y., et al.
- Journal Title
  
  J.Cell.Biochem. 109
  
  Pages: 1090-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791410
[Presentation] 転写抑制因子Blimp1は骨代謝制御の分子標的である2011
- Author(s)
  宮内芳輝、戸山芳昭、宮本健史
- Organizer
  第29回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-23592231
[Presentation] 転写抑制因子Blimp1は骨量制御の分子標的である2011
- Author(s)
  宮内芳輝、戸山芳昭、宮本健史
- Organizer
  第２９回日本骨代謝学会
- Place of Presentation
  大阪国際会議場（大阪府）
- Data Source
  KAKENHI-PROJECT-23592231
[Presentation] 転写抑制因子Blimp1とBcl6による破骨細胞分化制御2010
- Author(s)
  宮内芳輝
- Organizer
  第13回骨発生・再生研究会
- Place of Presentation
  東京
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21791410
[Presentation] Blimp1およびBc16による破骨細胞分化制御2010
- Author(s)
  宮内芳輝
- Organizer
  第13回骨発生・再生研究会
- Place of Presentation
  東京
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-21791410
[Presentation] 転写抑制因子Blimp1とBcl6による破骨細胞分化制御2010
- Author(s)
  宮内芳輝
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21791410
[Presentation] Blimp1およびBc16による破骨細胞分化制御2010
- Author(s)
  宮内芳輝、戸山芳昭、宮本健史
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-21791410
[Presentation] Transcriptional Regulation of Osteoclast Differentiation2009
- Author(s)
  Miyauchi, Y.
- Organizer
  第1回Orthopedic Research Club
- Place of Presentation
  かずさ
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21791410
[Presentation] Transcriptional regulation of osteoclast differentiation2009
- Author(s)
  宮内芳輝
- Organizer
  第1回Orthopedic Research Club
- Place of Presentation
  千葉
- Year and Date
  2009-11-01
- Data Source
  KAKENHI-PROJECT-21791410

1. MIYAMOTO Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 木崎昌弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYAUCHI Yoshiteru 宮内 芳輝

Research Projects

Research Products

Co-Researchers

Regulation of osteoclastogenesis by transcriptional repressor Blimp1 via epigenetic regulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of osteoclastogenesis by transcriptional repressorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PDGFBB promotes PDGFRα-positive cell migration into artificial bone in vivo.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neovascular niche for human myeloma cells in immunodeficient mouse bone.2012

Author(s)

Journal Title

Data Source

[Journal Article] An essential role for STAT6-STAT1 protein signaling in promoting macrophage cell-cell fusion.2012

Author(s)

Journal Title

Data Source

[Journal Article] Conditional inactivation of Blimp1 in adult mice promotes increased bone mass.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo behavior of multiple myeloma cells and their niche in immunodeficient mice2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] OC-STAMP and DC-STAMP cooperatively modulate cell-cell fusion to form osteoclasts and foreign body giant cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Matrix metalloproteinase 13 in the ligamentum flavum from lumbar spinal canal stenosis patients with and without diabetes mellitus.2011

Author(s)

Journal Title

Data Source

[Journal Article] The IRE1α-XBP1 pathway is essential for osteoblast differentiation through promoting transcription of Osterix.2011

Author(s)

Journal Title

Data Source

[Journal Article] Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization.2011

Author(s)

Journal Title

Data Source

[Journal Article] Suppressive effects for osteoclastogenesis regulated by RANKL signal.2011

Author(s)

Journal Title

Data Source

[Journal Article] Osteoclasts are dispensable for haematopoietic stem cell maintenance and mobilization2011

Author(s)

Journal Title

DOI

Data Source

MIYAUCHI Yoshiteru 宮内芳輝