OHTA Kinya 太田欣哉

Researcher Number	90448704
Affiliation (Current)	2025: 金城学院大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2016: 金城学院大学, 薬学部, 准教授 2014 – 2015: 名古屋市立大学, 大学院薬学研究科, 助教 2011 – 2015: 名古屋市立大学, 薬学研究科(研究院), 助教 2012: 名古屋市立大学, 大学院・薬学研究科, 助教 2008 – 2010: 名古屋市立大学, 大学院・薬学研究科, 助教
Review Section/Research Field	Principal Investigator Medical pharmacy Except Principal Investigator Medical pharmacy
Keywords	Principal Investigator スクリーニング / トランスポーター / 薬物相互作用 / 吸収 / 小腸 / 5-carboxyfluorescein / OATP2B1 / 薬物動態 / 薬物間相互作用 / 蛍光 / 有機カチオン / 医療薬剤学 … More Except Principal Investigator … More トランスポーター / 核酸塩基 / 吸収 / 小腸 / チャネル / アクアポリン10 / de novo / プリン塩基 / プリン核酸 / ガンシクロビル / ENBT1 / 代謝酵素 / 促進拡散 / 創薬標的 / 抗アレルギー薬 / 免疫 / 小胞体 / 樹状細胞 / アクアグリセロポリン / アクアポリン / クローニング / ナトリウム依存性 / 担体輸送 / グリセロール Less

Development of rapid functional assay system of OATP and screening of OATP inhibitor contained in food and drinkPrincipal Investigator
- Principal Investigator
  
  OHTA Kinya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kinjo Gakuin University
  Nagoya City University
Nucleobase Transport Function of Aquaporin 10: Its Role in the Intestinal Absorption of Nucleobases and Analogous Drugs
- Principal Investigator
  
  Yuasa Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Physiological role of a novel nucleobase transporter in the utilization of extracellular purine nucleobases
- Principal Investigator
  
  INOUE Katsuhisa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
  Nagoya City University
Functional Characteristics of a Novel Transporter Specifically Expressed in the Endoplasmic Reticulum in Dendritic Cells and its Role in Immune System
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Development of novel assay system for the functionality of organic cation transporters using fluorescent probe substratePrincipal Investigator
- Principal Investigator
  
  OHTA Kinya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University
Identification and Functional Analysis of the Na^+-Dependent Glycerol Transporter in HCT-15 Cells
- Principal Investigator
  
  YUASA Hiroaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nagoya City University

All 2016 2015 2014 2013 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Functional Characteristics of Aquaporin 7 as a Facilitative Glycerol Carrier2014
- Author(s)
  Takahiro Katano, Yuko Ito, Kinya Ohta, Tomoya Yasujima, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 29 Issue: 3 Pages: 244-248
- DOI
  10.2133/dmpk.DMPK-13-RG-121
- NAID
  130004463384
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460194
[Journal Article] Competitive Inhibition of AQP7-mediated Glycerol Transport by Glycerol Derivatives2014
- Author(s)
  Takahiro Katano, Yuko Ito, Kinya Ohta, Tomoya Yasujima, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 29 Issue: 4 Pages: 348-351
- DOI
  10.2133/dmpk.DMPK-13-NT-139
- NAID
  130004463387
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460194
[Journal Article] Evaluation of 4',6-diamidino-2-phenylindole as a fluorescent probe substrate for rapid assays of the functionality of human multidrug and toxin extrusion proteins.2010
- Author(s)
  Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Munenori Ishimaru, Hiroaki Yuasa
- Journal Title
  
  Drug Metab. Dispos. 38
  
  Pages: 715-721
- Data Source
  KAKENHI-PROJECT-21790155
[Journal Article] Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.2008
- Author(s)
  Yuriko Ohgusu, Kinya Ohta, Megumi Ishii, Takahiro Katano, Kimihiko Urano, Jun Watanabe, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Drug Metab.Pharmacokinet. 23
  
  Pages: 279-284
- NAID
  10021956401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590151
[Journal Article] Dual functional characteristic of human aquaporin 10 for solute transport.
- Author(s)
  Megumi Ishii, Kinya Ohta, Takahiro Katano, Kimihiko Urano, Jun Watanabe, Aki Miyamoto, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  Cell.Physiol.Biochem. in press
- NAID
  130004639733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590151
[Journal Article] Characterization of human OCT1-mediated transport of DAPI as a fluorescent probe substrate.
- Author(s)
  Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa
- Journal Title
  
  J. Pharm. Sci. in press.
- NAID
  130004639870
- Data Source
  KAKENHI-PROJECT-21790155
[Presentation] 消化管における各種医薬品の吸収を担うOATP2B1に対するコーヒーの影響2016
- Author(s)
  中村恭子, 関口裕太朗, 保嶋智也, 太田欣哉, 湯浅博昭
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2016
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-15K18930
[Presentation] 核酸塩基類似薬物の腸管吸収機構：ヒトとラットとの比較2016
- Author(s)
  湯浅博昭，水野加奈子，保嶋智也，太田欣哉
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  岐阜
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Characterization of OATP2B1-Mediated Transport of 5-Carboxyfluorescein for its Utilization for Fluorometric Rapid Assessment of the Functionality of OATP2B12015
- Author(s)
  関口裕太朗，太田欣哉，保嶋智也，井上勝央，湯浅博昭
- Organizer
  薬物動態学会，30回年会
- Place of Presentation
  東京
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-15K18930
[Presentation] 核酸塩基利用における核酸塩基トランスポーターENBT1と核酸代謝酵素との協働的効果2014
- Author(s)
  古川純士、井上勝央、太田欣哉、湯浅博昭
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-20
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] Functional characterization of a novel nucleobase transporter: cooperation with salvage enzymes in cellular nucleobase utilization2014
- Author(s)
  Furukawa J, Inoue K, Ohta K and Yuasa H
- Organizer
  19th North American International Society for the Study of Xenobiotics / 29th Japanese Society for the Study of Xenobiotics Meeting
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] aquaporin 10の新たな機能としての核酸塩基輸送：HEK293細胞一過性発現系におけるuracil輸送の解析2014
- Author(s)
  伊藤悠子，太田欣哉，井上勝央，湯浅博昭
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] aquaporin 10の新たな機能としての核酸塩基輸送：HEK293細胞一過性発現系におけるuracil輸送の解析2014
- Author(s)
  伊藤悠子，太田欣哉，井上勝央，湯浅博昭
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] 新規促進拡散型核酸塩基トランスポーターの機能解析：核酸代謝酵素との機能的協働2014
- Author(s)
  古川純士、井上勝央、太田欣哉、湯浅博昭
- Organizer
  第9回トランスポーター研究会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] 核酸塩基利用における新規核酸塩基トランスポーターと核酸代謝酵素の機能的協働効果2013
- Author(s)
  古川純士，井上勝央，太田欣哉，湯浅博昭
- Organizer
  日本薬物動態学会第28回年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590202
[Presentation] ヒトOCT1の蛍光性プローブ基質としてのDAPIの輸送特性の評価.2010
- Author(s)
  保嶋智也, 太田欣哉, 井上勝央, 湯浅博昭
- Organizer
  第25回日本薬物動態学会年会,要旨集,p.267(1-P-17).
- Place of Presentation
  さいたま
- Data Source
  KAKENHI-PROJECT-21790155
[Presentation] ヒトアクアポリン3のグリセロール輸送特性2010
- Author(s)
  宮本明希, 太田欣哉, 片野貴大, 浦野公彦, 渡辺淳, 井上勝央, 湯浅博昭
- Organizer
  第25回日本薬物動態学会年会
- Place of Presentation
  さいたま
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] Characterization of the transport of DAPI by hOCT1 for its utilization for rapid uptake assays.2010
- Author(s)
  Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa
- Organizer
  Pharmaceutical Sciences World Congress 2010 (4th),AAPS J, 12(S2), Abstract T3402.
- Place of Presentation
  New Orleans, Louisiana, U.S.A.
- Data Source
  KAKENHI-PROJECT-21790155
[Presentation] Rapid screening of inhibitors for human organic cation transporter 1 using DAPI.2010
- Author(s)
  Tomoya Yasujima, Kinya Ohta, Katsuhisa Inoue, Hiroaki Yuasa
- Organizer
  第4回次世代を担う若手医療薬科学シンポジウム,要旨集,p.77(P32).
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21790155
[Presentation] hOCT1による蛍光性核染色剤DAPIの輸送:迅速機能評価への応用の可能性2010
- Author(s)
  保嶋智也, 太田欣哉, 井上勝央, 石丸宗徳, 湯浅博昭
- Organizer
  日本薬学会第130年会,要旨集,No.4,p.209(28P-am026).
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21790155
[Presentation] ヒトアクアポリン3のglycerol輸送機構の双機能的特性2009
- Author(s)
  片野貴大, 杉本さや香, 浦野公彦, 宮本明希, 太田欣哉, 井上勝央, 渡辺淳, 湯浅博昭
- Organizer
  第55回日本薬学会東海支部大会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] ヒトアクアポリン10の物質輸送における双機能的特性2009
- Author(s)
  石井めぐみ, 太田欣哉, 片野貴大, 浦野公彦, 渡辺淳, 井上勝央, 湯浅博昭
- Organizer
  第24回日本薬物動態学会年会
- Place of Presentation
  京都
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] ヒトアクアポリン10の促進拡散型グリセロール輸送担体としての機能解析2008
- Author(s)
  石井めぐみ, 太田欣哉, 片野貴大, 浦野公彦, 渡辺淳, 井上勝央, 湯浅博昭
- Organizer
  第23回日本薬物動態学会年会
- Place of Presentation
  熊本
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20590151
[Presentation] 蛍光性色素DAPIを用いたMATE輸送機能の迅速評価法2008
- Author(s)
  保嶋智也, 太田欣哉, 井上勝央, 湯浅博昭
- Organizer
  第23回日本薬物動態学会年会,要旨集,p.257(31B11-5).
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-21790155
[Presentation] Caco-2細胞におけるプリン型核酸塩基類の輸送の解析
- Author(s)
  田島健太郎, 水野加奈子, 太田欣哉, 湯浅博昭
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Caco-2細胞における5-fluorouracil輸送の解析
- Author(s)
  水野加奈子，太田欣哉，湯浅博昭
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  さいたま
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Carrier-mediated uptake of adenine in Caco-2 cells
- Author(s)
  Kentaro Tajima, Kanako Mizuno, Kinya Ohta, Hiroaki Yuasa
- Organizer
  19th NA ISSX/29th JSSX Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25460194
[Presentation] Caco-2細胞における6-mercaptopurine輸送の解析
- Author(s)
  水野加奈子, 田島健太郎, 太田欣哉, 湯浅博昭
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460194

1. YUASA Hiroaki (20191471)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
2. INOUE KATSUHISA (50315892)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results

OHTA Kinya 太田 欣哉

Research Projects

Research Products

Co-Researchers

Development of rapid functional assay system of OATP and screening of OATP inhibitor contained in food and drinkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nucleobase Transport Function of Aquaporin 10: Its Role in the Intestinal Absorption of Nucleobases and Analogous Drugs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological role of a novel nucleobase transporter in the utilization of extracellular purine nucleobases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional Characteristics of a Novel Transporter Specifically Expressed in the Endoplasmic Reticulum in Dendritic Cells and its Role in Immune System

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel assay system for the functionality of organic cation transporters using fluorescent probe substratePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and Functional Analysis of the Na^+-Dependent Glycerol Transporter in HCT-15 Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Functional Characteristics of Aquaporin 7 as a Facilitative Glycerol Carrier2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Competitive Inhibition of AQP7-mediated Glycerol Transport by Glycerol Derivatives2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Evaluation of 4',6-diamidino-2-phenylindole as a fluorescent probe substrate for rapid assays of the functionality of human multidrug and toxin extrusion proteins.2010

Author(s)

Journal Title

Data Source

[Journal Article] Functional characterization of human aquaporin 9 as a facilitative glycerol carrier.2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Dual functional characteristic of human aquaporin 10 for solute transport.

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Characterization of human OCT1-mediated transport of DAPI as a fluorescent probe substrate.

Author(s)

Journal Title

NAID

Data Source

[Presentation] 消化管における各種医薬品の吸収を担うOATP2B1に対するコーヒーの影響2016

Author(s)

Organizer

Place of Presentation

Data Source

OHTA Kinya 太田欣哉