Konishi Hiroyuki 小西博之

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KONISHI Hiroyuki 小西博之

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Researcher Number	90448746
Other IDs
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 教授 2025: 名古屋大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 名古屋大学, 医学系研究科, 准教授 2021: 名古屋大学, 医学系研究科, 准教授 2019 – 2020: 名古屋大学, 医学系研究科, 講師 2018: 名古屋大学, 大学院医学系研究科, 講師 2016 – 2018: 名古屋大学, 医学系研究科, 助教 … More 2015: 名古屋大学, 大学院医学系研究科, 助教 2012 – 2015: 名古屋大学, 医学(系)研究科(研究院), 助教 2011 – 2012: 名古屋大学, 大学院・医学系研究科, 助教 2011: 名古屋大学, 医学系研究科, 助教 2007 – 2010: 大阪市立大学, 大学院・医学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 46010:Neuroscience-general-related / Neurochemistry/Neuropharmacology / Transformative Research Areas, Section (III) / Neurochemistry/Neuropharmacology Except Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including histology/embryology) / Biological Sciences / Biological Sciences
Keywords	Principal Investigator 神経損傷 / ミクログリア / グリア / 炎症 / 損傷 / 硬膜 / リンパ管 / マーカー / マクロファージ / 再生医学 … More / 神経再生 / 脳梗塞 / 髄膜 / アストロサイト / 末梢神経 / 神経障害性疼痛 / サイトカイン / DAP12 / TREM2 / ミクログリアマーカー / アロディニア / 疼痛 / 神経炎症 / モノクローナル抗体 / 抗体 / 糖鎖 / 細胞・組織 / 脳・神経 / 神経科学 / グリア細胞 … More Except Principal Investigator 運動ニューロン / 軸索再生 / ATF3 / DINE / 神経再生 / 神経損傷 / トランスジェニック / 解剖学 / 末梢神経 / シュワン細胞 / 脳・神経 / 脳神経疾患 / 細胞・組織 / 軸索損傷 / 神経変性 / オルガネラ / 運動神経 / 軸索障害 / ミトコンドリア / プロテーオミクス / 国際情報交換（イギリス） / 国際研究者交流 / ECEL1 / DA5D / 先天性間接拘縮症 / グリア / DINE/ECEL1 / ノックアウト / DINE / ECEL1 / 神経筋接合部 / プロテアーゼ / 組織再生 / STAT3 / 転写因子 / 再生医学 / 脳神経 / シュワン増殖 / Regファミリー / Reg / PAP / ラッフリング / アネキシン / サイトカイン / マクロファージ / CCR5 / ミクログリア / 舌下神経 / マウス Less

グリアとリンパ管のインターラクションによる脳病態制御Principal Investigator
- Principal Investigator
  
  小西博之
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nagoya University
脳損傷後に起こる硬膜リモデリングのメカニズムと意義Principal Investigator
- Principal Investigator
  
  小西博之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Nagoya University
Origin and function of macrophages in the peripheral nervous systemPrincipal Investigator
- Principal Investigator
  
  Konishi Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Nagoya University
Effects of a DAP12-mediated signal on microglial activation after injuryPrincipal Investigator
- Principal Investigator
  
  Konishi Hiroyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya University
Organelle dynamics for fate determination of injured neurons
- Principal Investigator
  
  Kiyama Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Nagoya University
Expression and function of Siglec-H in the nervous systemPrincipal Investigator
- Principal Investigator
  
  Konishi Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya University
Functional consequences of glia-neuron interactions in degenerating and regenerating neurons
- Principal Investigator
  
  Kiyama HIroshi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
An involvement of damage induced neuronal endopeptidase DINE in construction of neuro-muscular junction.
- Principal Investigator
  
  KIYAMA Hiroshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Nagoya University
  Osaka City University
Analyses of N-terminal processing of secretory lectin PAP-III in neuronal regenerationPrincipal Investigator
- Principal Investigator
  
  KONISHI Hiroyuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya University
  Osaka City University
Identification of a transcription factor complex which promotes nerve regeneration
- Principal Investigator
  
  KIYAMA Hiroshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Osaka City University
グリア・ニュロン相互作用による神経機能維持メカニズムとその加齢変化の解析
- Principal Investigator
  
  KIYAMA Hiroshi
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka City University

[Journal Article] Repeated cold stress, an animal model for fibromyalgia, elicits proprioceptor-induced chronic pain with microglial activation in mice2024
- Author(s)
  Wakatsuki K, Kiryu-Seo S, Yasui M, Yokota H, Kida H, Konishi H, Kiyama H
- Journal Title
  
  J Neuroinflammation
  
  Volume: 21 Issue: 1 Pages: 25-25
- DOI
  10.1186/s12974-024-03018-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05962, KAKENHI-PROJECT-21K11688, KAKENHI-PROJECT-21K19310, KAKENHI-PUBLICLY-23H04162, KAKENHI-PUBLICLY-23H04229, KAKENHI-PROJECT-23K24695
[Journal Article] Phagocytic astrocytes: Emerging from the shadows of microglia2022
- Author(s)
  Konishi Hiroyuki、Koizumi Schuichi、Kiyama Hiroshi
- Journal Title
  
  Glia
  
  Volume: － Issue: 6 Pages: 1009-1026
- DOI
  10.1002/glia.24145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19H03395, KAKENHI-PLANNED-20H05902, KAKENHI-PROJECT-21H04786, KAKENHI-PROJECT-23K24695
[Journal Article] A mouse model of microglia-specific ablation in the embryonic central nervous system2021
- Author(s)
  Li Chenmin、Konishi Hiroyuki、Nishiwaki Kimitoshi、Sato Katsuaki、Miyata Takaki、Kiyama Hiroshi
- Journal Title
  
  Neuroscience Research
  
  Volume: 173 Pages: 54-61
- DOI
  10.1016/j.neures.2021.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19H03395
[Journal Article] Morphology, localization, and postnatal development of dural macrophages.2021
- Author(s)
  Sato T, Konishi H, Tamada H, Nishiwaki K, Kiyama H
- Journal Title
  
  Cell Tissue Res
  
  Volume: 384(1) Issue: 1 Pages: 49-58
- DOI
  10.1007/s00441-020-03346-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08355, KAKENHI-PROJECT-19H03395, KAKENHI-PROJECT-19K06904
[Journal Article] Non-pathological roles of microglial TREM2/DAP12: TREM2/DAP12 regulates the physiological functions of microglia from development to aging2020
- Author(s)
  Konishi Hiroyuki、Kiyama Hiroshi
- Journal Title
  
  Neurochemistry International
  
  Volume: 141 Pages: 104878-104878
- DOI
  10.1016/j.neuint.2020.104878
- NAID
  120007145980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19H03395
[Journal Article] Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction2020
- Author(s)
  Konishi Hiroyuki、Okamoto Takayuki、Hara Yuichiro、Komine Okiru、Tamada Hiromi、Maeda Mitsuyo、Osako Fumika、Kobayashi Masaaki、Nishiyama Akira、Kataoka Yosky、Takai Toshiyuki、Udagawa Nobuyuki、Jung Steffen、Ozato Keiko、Tamura Tomohiko、Tsuda Makoto、Yamanaka Koji、Ogi Tomoo、Sato Katsuaki、Kiyama Hiroshi
- Journal Title
  
  The EMBO Journal
  
  Volume: 39 Issue: 22
- DOI
  10.15252/embj.2020104464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19K07372, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-20K21689, KAKENHI-PROJECT-19H05658, KAKENHI-PROJECT-18H02724, KAKENHI-PROJECT-19H03395, KAKENHI-PROJECT-17KK0191
[Journal Article] Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model2020
- Author(s)
  Koshimizu Hiroyuki、Ohkawara Bisei、Nakashima Hiroaki、Ota Kyotaro、Kanbara Shunsuke、Inoue Taro、Tomita Hiroyuki、Sayo Akira、Kiryu-Seo Sumiko、Konishi Hiroyuki、Ito Mikako、Masuda Akio、Ishiguro Naoki、Imagama Shiro、Kiyama Hiroshi、Ohno Kinji
- Journal Title
  
  Life Sciences
  
  Volume: 263 Pages: 118577-118577
- DOI
  10.1016/j.lfs.2020.118577
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06483, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-19K24067, KAKENHI-PROJECT-18H02524, KAKENHI-PROJECT-19H03779, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-17K07094
[Journal Article] 活性化ミクログリアの新たなタイプとその活性化誘導のメカニズム2019
- Author(s)
  小西博之、木山博資
- Journal Title
  
  実験医学
  
  Volume: 37 Pages: 872-877
- Data Source
  KAKENHI-PROJECT-19K06904
[Journal Article] 損傷神経細胞にみられる分子とオルガネラの再編とその意義2019
- Author(s)
  木山博資、小西博之、桐生寿美子
- Journal Title
  
  生体の科学
  
  Volume: 70 Pages: 58-62
- Data Source
  KAKENHI-PROJECT-16H05117
[Journal Article] GPR34 in spinal microglia exacerbates neuropathic pain in mice2019
- Author(s)
  Sayo Akira、Konishi Hiroyuki、Kobayashi Masaaki、Kano Kuniyuki、Kobayashi Hiroki、Hibi Hideharu、Aoki Junken、Kiyama Hiroshi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 16 Issue: 1 Pages: 23-33
- DOI
  10.1186/s12974-019-1458-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05494, KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19K24067, KAKENHI-PROJECT-19H03395
[Journal Article] Dual functions of microglia in the formation and refinement of neural circuits during development2019
- Author(s)
  Konishi H, Kiyama H, Ueno M
- Journal Title
  
  Int J Developmental Neuroscience
  
  Volume: 印刷中 Issue: 1 Pages: 18-25
- DOI
  10.1016/j.ijdevneu.2018.09.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05743, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-17K19443, KAKENHI-PROJECT-19H03395, KAKENHI-PROJECT-17H04985
[Journal Article] Dual microglia effects on blood brain barrier permeability induced by systemic inflammation2019
- Author(s)
  Haruwaka Koichiro、Ikegami Ako、Tachibana Yoshihisa、Ohno Nobuhiko、Konishi Hiroyuki、Hashimoto Akari、Matsumoto Mami、Kato Daisuke、Ono Riho、Kiyama Hiroshi、Moorhouse Andrew J.、Nabekura Junichi、Wake Hiroaki
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 5816-5816
- DOI
  10.1038/s41467-019-13812-z
- NAID
  120006786954
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06852, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-18KK0070, KAKENHI-PUBLICLY-18H04946, KAKENHI-PUBLICLY-19H04753, KAKENHI-PUBLICLY-19H05219, KAKENHI-PROJECT-18H02598, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-17H01530
[Journal Article] Necroptosis of intestinal epithelial cells induces type 3 innate lymphoid cell-dependent lethal ileitis.2019
- Author(s)
  Shindo R, Ohmuraya M, Komazawa-Sakon S, Miyake S, Deguchi Y, Yamazaki S, Nishina T, Yoshimoto T, Kakuta S, Koike M, Uchiyama Y, Konishi H, Kiyama H, Mikami T, Moriwaki K, Araki K, Nakano H.
- Journal Title
  
  iScience
  
  Volume: 15 Pages: 536-551
- DOI
  10.1016/j.isci.2019.05.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07333, KAKENHI-PROJECT-18K11658, KAKENHI-PROJECT-19K06570, KAKENHI-PROJECT-19K06904, KAKENHI-PROJECT-19K07516, KAKENHI-PROJECT-19K08405, KAKENHI-PROJECT-19K09105, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-17K08522, KAKENHI-PROJECT-17K08994, KAKENHI-PROJECT-19K07391
[Journal Article] Microglial TREM2/DAP12 Signaling: A Double-Edged Sword in Neural Diseases2018
- Author(s)
  Konishi Hiroyuki、Kiyama Hiroshi
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 12:206
- DOI
  10.3389/fncel.2018.00206
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05743, KAKENHI-PROJECT-16K07055
[Journal Article] Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters2018
- Author(s)
  Ito Kenyu、Ohkawara Bisei、Yagi Hideki、Nakashima Hiroaki、Tsushima Mikito、Ota Kyotaro、Konishi Hiroyuki、Masuda Akio、Imagama Shiro、Kiyama Hiroshi、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  Sceintific Reports
  
  Volume: 8 Issue: 1 Pages: 434-434
- DOI
  10.1038/s41598-017-18753-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-17K16688, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-16H05446, KAKENHI-PROJECT-15K06755
[Journal Article] Branched Sialylated <i>N</i>-glycans Are Accumulated in Brain Synaptosomes and Interact with Siglec-H2018
- Author(s)
  M. Handa-Narumi, T. Yoshimura, H. Konishi, Y. Fukata, Y. Manabe, K. Tanaka, G.-m. Bao, H. Kiyama, K. Fukase, K. Ikenaka
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 43 Issue: 2 Pages: 141-152
- DOI
  10.1247/csf.18009
- NAID
  130007439439
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19154, KAKENHI-PLANNED-15H05836, KAKENHI-PLANNED-15H05843, KAKENHI-PROJECT-16H01885, KAKENHI-PROJECT-16H03287, KAKENHI-PROJECT-16H05924, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-17K19201
[Journal Article] Agonists for G-protein-coupled receptor 84 (GPR84) alter cellular morphology and motility but do not induce pro-inflammatory responses in microglia2017
- Author(s)
  Wei Li、Tokizane Kyohei、Konishi Hiroyuki、Yu Hua-Rong、Kiyama Hiroshi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 14 Issue: 1 Pages: 198-198
- DOI
  10.1186/s12974-017-0970-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07055, KAKENHI-PUBLICLY-17H05743, KAKENHI-PROJECT-16K15170
[Journal Article] Siglec-H is a microglia-specific marker that discriminates microglia from CNS-associated macrophages and CNS-infiltrating monocytes2017
- Author(s)
  Konishi Hiroyuki、Kobayashi Masaaki、Kunisawa Taikan、Imai Kenta、Sayo Akira、Malissen Bernard、Crocker Paul R.、Sato Katsuaki、Kiyama Hiroshi
- Journal Title
  
  Glia
  
  Volume: 65 Issue: 12 Pages: 1927-1943
- DOI
  10.1002/glia.23204
- NAID
  120006375875
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07055, KAKENHI-PUBLICLY-17H05743
[Journal Article] Exposure to diphtheria toxin during the juvenile period impairs both inner and outer hair cells in C57BL/6 mice2017
- Author(s)
  Konishi H, Ohgami N, Matsushita A, Kondo Y, Aoyama Y, Kobayashi M, Nagai T, Ugawa S, Yamada K, Kato M, Kiyama H
- Journal Title
  
  Neuroscience
  
  Volume: 印刷中 Pages: 15-23
- DOI
  10.1016/j.neuroscience.2017.03.028
- NAID
  120006331816
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-16K08343, KAKENHI-PROJECT-17K19483, KAKENHI-PUBLICLY-16H01639, KAKENHI-PROJECT-15H01743, KAKENHI-PROJECT-17H02220, KAKENHI-ORGANIZER-15H05935
[Journal Article] Phospholipid localization implies microglial morphology and function via Cdc42 in vitro2017
- Author(s)
  Kyohei Tokizane, Hiroyuki Konishi, Kumiko Makide, Hiroki Kawana, Shinichi Nakamuta, Kozo Kaibuchi, Tomohiko Ohwada, Junken Aoki, Hiroshi Kiyama
- Journal Title
  
  Glia
  
  Volume: 65 Issue: 5 Pages: 740-755
- DOI
  10.1002/glia.23123
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J02662, KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-16K15113, KAKENHI-PROJECT-16H05085, KAKENHI-PROJECT-16H05117
[Journal Article] TREM2/DAP12 Signal Elicits Proinflammatory Response in Microglia and Exacerbates Neuropathic Pain2016
- Author(s)
  Kobayashi M, Konishi H, Sayo A, Takai T, Kiyama H
- Journal Title
  
  J Neurosci
  
  Volume: 36(43) Issue: 43 Pages: 11138-11150
- DOI
  10.1523/jneurosci.1238-16.2016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K07055, KAKENHI-PROJECT-16K15170
[Journal Article] R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5.2016
- Author(s)
  Nakashima H., Ohkawara B., Ishigaki S., Fukudome T., Ito K., Tsushima M., Konishi H., Okuno T., Yoshimura T., Ito M., Masuda A., Sobue G., Kiyama H., Ishiguro N., Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 22 Issue: 1 Pages: 28512-28512
- DOI
  10.1038/srep28512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26117002, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-25430049, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-15K09310, KAKENHI-PROJECT-16K07055, KAKENHI-ORGANIZER-26117001
[Journal Article] Ontogeny and innervation of taste buds in mouse palatal gustatory epithelium2016
- Author(s)
  Rashwan A, Konishi H, El-Sharaby A, Kiyama H
- Journal Title
  
  J Chemical Neuroanatomy
  
  Volume: 71 Pages: 26-40
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23111007
[Journal Article] Phenylbutazone induces expression of MBNL1 and suppresses formation of MBNL1-CUG RNA foci in a mouse model of myotonic dystrophy2016
- Author(s)
  1.Chen G, Masuda A, Konishi H, Ohkawara B, Ito M, Kinoshita M, Kiyama H, Matsuura T, Ohno K.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 25317-25317
- DOI
  10.1038/srep25317
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-26670170, KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15K06755, KAKENHI-PROJECT-16K07055
[Journal Article] Increase of transcription factor EB (TFEB) and lysosomes in rat DRG neurons and their transportation to the central nerve terminal in dorsal horn after nerve injury2016
- Author(s)
  Jung J, Uesugi N, Jeong NY, Park BS, Konishi H, Kiyama H
- Journal Title
  
  Neuroscience
  
  Volume: 313 Pages: 10-22
- DOI
  10.1016/j.neuroscience.2015.11.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830050, KAKENHI-PLANNED-23111007
[Journal Article] Ontogeny and innervation of taste buds in mouse palatal gustatory epithelium2016
- Author(s)
  Rashwan A, Konishi H, El-Sharaby A, Kiyama H
- Journal Title
  
  J Chem Neuroanat
  
  Volume: 71 Pages: 26-40
- DOI
  10.1016/j.jchemneu.2015.11.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830050
[Journal Article] A DAP12-Dependent Signal Promotes Pro-Inflammatory Polarization in Microglia Following Nerve Injury and Exacerbates Degeneration of Injured Neurons.2015
- Author(s)
  Kobayashi M, Konishi H, Takai T, Kiyama H.
- Journal Title
  
  Glia
  
  Volume: 63 Issue: 6 Pages: 1073-1082
- DOI
  10.1002/glia.22802
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461597, KAKENHI-PROJECT-25830050, KAKENHI-PLANNED-23111007
[Journal Article] Dysfunction in the hypothalamo- hypophyseal system under chronic stress and fatigue2013
- Author(s)
  Ogawa T., Konishi H., Kiyama H
- Journal Title
  
  Advance in Neuroimmune Biology
  
  Volume: 4 Issue: 4 Pages: 219-228
- DOI
  10.3233/nib-130070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590240, KAKENHI-PROJECT-25830050
[Journal Article] Continuous stress promotes expression of VGF in melanotroph via suppression of dopamine2013
- Author(s)
  Kyohei Tokizane
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 372 Issue: 1-2 Pages: 4956-4956
- DOI
  10.1016/j.mce.2013.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023, KAKENHI-PROJECT-23310155, KAKENHI-PROJECT-23590240, KAKENHI-PROJECT-25461402, KAKENHI-PROJECT-25670093, KAKENHI-PROJECT-25830050
[Journal Article] N-terminal Cleaved Pancreatitis-Associated Protein-III (PAP-III) Serves as a Scaffold for Neurites and Promotes Neurite Outgrowth2013
- Author(s)
  Konishi H, Matsumoto S, Namikawa K, Kiyama H
- Journal Title
  
  J Biol Chem
  
  Volume: 288(15) Pages: 10205-10213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390035
[Journal Article] N-terminal Cleaved Pancreatitis-associated Protein-III (PAP-III) Serves as a Scaffold for Neurites and Promotes Neurite Outgrowth.2013
- Author(s)
  H. Konishi, S. Mateumoto, K. Namikawa, H. Kiyama
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 288(15) Issue: 15 Pages: 10205-10213
- DOI
  10.1074/jbc.m112.395301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07370, KAKENHI-PROJECT-25830050, KAKENHI-PLANNED-23111007
[Journal Article] Analysis on expression of the regenerating gene(Reg) family members Reg-IIIβand Reg-IIIγin the mouse during deve lopment2012
- Author(s)
  Matsumoto S, Konishi H, Maeda R, Kiryu-Seo S, Kiyama H.
- Journal Title
  
  J Comp Neuro
  
  Volume: 520(3) Pages: 479-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Expression analysis of the regenerating gene (Reg) family members Reg-IIIβand Reg-IIIγin the mouse during development2012
- Author(s)
  Matsumoto S, Konishi H, Maeda R, Kiryu-Seo S, Kiyama H
- Journal Title
  
  J Comp Nuerol
  
  Volume: 520 Issue: 3 Pages: 479-494
- DOI
  10.1002/cne.22705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500314, KAKENHI-PROJECT-22700398
[Journal Article] Expression analysis of the regenerating gene (Reg) family members Reg-IIIβ and Reg-IIIγ in the mouse during development2012
- Author(s)
  Matsumoto S, Konishi H, Maeda R, Kiryu-Seo S, Kiyama H
- Journal Title
  
  The Journal of Comparative Neurology
  
  Volume: 520-3 Pages: 479-494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390035
[Journal Article] Pancreatitis- associated protein-I and pancreatitis associated protein-III expression in a rat model of kainic acid-induced seizure2011
- Author(s)
  Kawahara S, Konishi H, Morino M, Ohata K, Kiyama H
- Journal Title
  
  Neuroscience
  
  Volume: 175 Pages: 273-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390035
[Journal Article] Analysis on expression of the regenerating gene (Reg) family members Reg-IIIb and Reg-IIIg in the mouse during development2011
- Author(s)
  Matsumoto S, Konishi H, Maeda R, Kiryu-Seo S, Kiyama H
- Journal Title
  
  J Comp Neurol
  
  Volume: 520(3) Pages: 479-494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390035
[Journal Article] Pancreatitis-associated protein-I and pancreatitis-associated protein-III expression in a rat model of kainic acid-induced seizure2011
- Author(s)
  Kawahara S, Konishi H, Morino M, Ohata K, Kiyama H.
- Journal Title
  
  Neuroscienc
  
  Volume: 175 Pages: 273-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Continuous stress-induced dopamine dysregulation augments PAP-I and PAP-II expression in melanotrophs of the pituitary gland2011
- Author(s)
  小西博之、小川登紀子、川原慎一、松本早紀子、木山博資
- Journal Title
  
  Biochemical and Biophysical Research Communication
  
  Volume: 407(1) Issue: 1 Pages: 7-12
- DOI
  10.1016/j.bbrc.2011.02.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Pancreatitis-associated protein-I and pancreatitis associated protein-III expression in a rat model of kainic acid-induced seizure2011
- Author(s)
  Kawahara S, Konishi H, Morino M, Ohata K, Kiyama H
- Journal Title
  
  Neuroscience
  
  Volume: 175 Pages: 273-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390035
[Journal Article] Continuous stress-induced dopamine dysregulation augments PAP-I and PAP-II expression in melanotrophs of the pituitary gland2011
- Author(s)
  Konishi H, Ogawa T, Kawahara S, Matsumoto S, Kiyama H.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407(1) Pages: 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Id1, Id2 and Id3 are induced in rat melanotrophs of the pituitary gland by dopamine suppression under continuous stress2010
- Author(s)
  小西博之
- Journal Title
  
  Neuroscience
  
  Volume: 169(4) Pages: 1527-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Id1, Id2 and Id3 are induced in rat melanotrophs of the pituitary gland by dopamine suppression under continuousstress2010
- Author(s)
  Konishi H, Ogawa T, Nakagomi S, Inoue K, Tohyama M, Kiyama H.
- Journal Title
  
  Neuroscienc
  
  Volume: 169(4) Pages: 1527-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Local ventilation system successfully reduced formaldehyde exposure during gross anatomy dissection classes2010
- Author(s)
  Takahashi M, Abe M, Yamagishi T, Nakatani K, Okade T, Ogawa T, Konishi H, Kiryu-Seo S, Kiyama H, Nakajima Y.
- Journal Title
  
  Anat Sci Int
  
  Volume: 85(4) Pages: 251-2
- NAID
  10031162230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Journal Article] Simultaneous expression of glutathione, thioredoxin-1, and their reductases in nerve transected hypoglossal motor neurons of rat.2010
- Author(s)
  Hama I, Nakagomi S, Konishi H, Kiyama H
- Journal Title
  
  Brain Res 1306
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] Induction of pancreatitis-associated protein (PAP) family members in neurons following traumatic brain injury2009
- Author(s)
  Ampo K, Suzuki A, Konishi H, Kivama H
- Journal Title
  
  J Neurotrauma 26(10)
  
  Pages: 1683-1693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] Induction of pancreatitis-associated protein (PAP) family members in neurons following traumatic brain injury2009
- Author(s)
  Ampo K, Suzuki A, Konishi H, Kiyama H
- Journal Title
  
  J Neurotrauma 26(10)
  
  Pages: 1683-1693
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] Simultaneous expression of glutathione, thioredoxin-1, and their reductases in nerve transected hypoglossal motor neurons of rat2009
- Author(s)
  Hama I, Nakagomi S, Konishi H, Kiyama H
- Journal Title
  
  Brain Res 1306
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] G protein coupled receptor screen reveals a role for chemokine receptor CCR5 in suppressing microglial neurotoxicity2008
- Author(s)
  Gamo K, Kiryu-Seo S, Konishi H, Aoki S, Matsushima K, Wada K, Kiyama H
- Journal Title
  
  J Neurosci 28(46)
  
  Pages: 11980-11988
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] Identification of peripherin as a novel Akt substrate in neurons2007
- Author(s)
  Konishi H, Namikawa K, Shikata K, Kobatake Y, Tachibana T, Kiyama H
- Journal Title
  
  J Biol Chem 282(32)
  
  Pages: 23491-23499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] Identification of peripherin as a Akt substrate in neurons2007
- Author(s)
  Konishi H, Namikawa K, Shikata K, Kobatake Y, Tachibana T, Kiyama H
- Journal Title
  
  J Biol Chem 282(32)
  
  Pages: 23491-23499
- Data Source
  KAKENHI-PROJECT-19209005
[Journal Article] Identification of peripherin as a novel Akt substrate in neurons2007
- Author(s)
  Konishi H, Namikawa K, Shikata K, Kobatake Y, Tachibana T, Kiyama H
- Journal Title
  
  J Biol Chem 282(32)
  
  Pages: 23491-23499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15082205
[Journal Article] Pancreatitis-associated protein-III (PAP-III) is a novel macrophage chemoattractant implicated in nerve regeneration2006
- Author(s)
  Namikawa K, Okamoto T, Suzuki A, Konishi H, Kiyama H
- Journal Title
  
  J Neurosci 26(28)
  
  Pages: 7460-7467
- Data Source
  KAKENHI-PROJECT-15082205
[Journal Article] Annexin III implicated in the microglial response to motor nerve injury.2006
- Author(s)
  Konishi H, Namikawa K, Kiyama H
- Journal Title
  
  Glia in press
- Data Source
  KAKENHI-PROJECT-15082205
[Journal Article] The p53-independent nuclear translocation of Cyclin G1 in degenerating neurons by ischemic and traumatic insults.2005
- Author(s)
  Maeda M, Ampo K, Kiryu-Seo S, Konishi H, Ohba N, Kadono C, Kiyama H
- Journal Title
  
  Exp Neurol 193(2)
  
  Pages: 350-360
- Data Source
  KAKENHI-PROJECT-15082205
[Journal Article] Continuous stress-induced dopamine dysregulation augments PAP-I and PAP-II expression in melanotrophs of the pituitary gland
- Author(s)
  小西博之
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] 硬膜内リンパ管のリモデリングによる脳病態制御2024
- Author(s)
  小西博之、木山博資
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-23K05962
[Presentation] 硬膜内リンパ管のリモデリングによる脳損傷部位からの細胞残骸排出2024
- Author(s)
  小西博之
- Organizer
  第7回包括的神経グリア研究会
- Data Source
  KAKENHI-PUBLICLY-23H04162
[Presentation] 硬膜内リンパ管のリモデリングによる脳損傷部位からの細胞残骸排出2024
- Author(s)
  小西博之
- Organizer
  第7回包括的神経グリア研究会
- Data Source
  KAKENHI-PROJECT-23K05962
[Presentation] 硬膜内リンパ管のリモデリングによる脳病態制御2024
- Author(s)
  小西博之、木山博資
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PUBLICLY-23H04162
[Presentation] Interactions of glial cells with lymphatic vessels in the injured brain2023
- Author(s)
  小西博之、木山博資
- Organizer
  第64回日本神経病理学会総会学術研究会・第66回日本神経化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-23K05962
[Presentation] リンパ管のリモデリングによる脳病態制御2023
- Author(s)
  小西博之、木山博資
- Organizer
  第83回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PUBLICLY-23H04162
[Presentation] Interactions of glial cells with lymphatic vessels in the injured brain2023
- Author(s)
  小西博之、木山博資
- Organizer
  第64回日本神経病理学会総会学術研究会・第66回日本神経化学会大会合同大会
- Data Source
  KAKENHI-PUBLICLY-23H04162
[Presentation] 脳損傷部位に形成されるリンパ管網による細胞残骸排出システム2023
- Author(s)
  小西博之、木山博資
- Organizer
  第42回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04162
[Presentation] Interactions of glial cells with lymphatic vessels in the injured brain2023
- Author(s)
  Konishi H, Kiyama H
- Organizer
  The 50th Naito Conference on Glia World
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04162
[Presentation] リンパ管のリモデリングによる脳病態制御2023
- Author(s)
  小西博之、木山博資
- Organizer
  第83回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-23K05962
[Presentation] 脳損傷部位に形成されるリンパ管網による細胞残骸排出システム2023
- Author(s)
  小西博之、木山博資
- Organizer
  第42回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K05962
[Presentation] Interactions of glial cells with lymphatic vessels in the injured brain2023
- Author(s)
  Konishi H, Kiyama H
- Organizer
  The 50th Naito Conference on Glia World
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05962
[Presentation] Interplay of microglia and astrocytes in phagocytosis2022
- Author(s)
  Konishi Hiroyuki
- Organizer
  The third international symposium on brain science: University of Yamanashi
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] ミクログリアを含めた神経系マクロファージのサブタイプ2022
- Author(s)
  小西博之、木山博資
- Organizer
  第127回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction2021
- Author(s)
  Hiroyuki Konishi
- Organizer
  第3回名古屋大学CIBoGリトリート
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] 貪食におけるミクログリアとアストロサイトの連携2021
- Author(s)
  小西博之、木山博資
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] ミクログリアと中枢神経系境界部に存在するマクロファージの相違点2021
- Author(s)
  小西博之、木山博資
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] アストロサイトはミクログリア機能低下時に貪食作用を発揮する2021
- Author(s)
  小西博之、岡本峻幸、佐藤克明、木山博資
- Organizer
  第126回日本解剖学会総会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] 胎児ミクログリア機能を研究するためのミクログリア特異的アブレーションシステム2021
- Author(s)
  李晨旻、小西博之、西脇公俊、佐藤克明、宮田卓樹、木山博資
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] 発達期白質のMac2陽性細胞の分布2021
- Author(s)
  Tomoko Ishibashi, Takei Yuika, Ohshima Shiho, Hashimoto Kouichi, Konishi Hiroyuki, Kiyama Hiroshi, Baba Hiroko
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] 脳虚血は硬膜の組織的構造を変化させる2021
- Author(s)
  髙橋優太、小西博之、木山博資
- Organizer
  第126回日本解剖学会総会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] Astrocytic phagocytosis compensates for microglial dysfunction2020
- Author(s)
  小西博之、岡本峻幸、佐藤克明、木山博資
- Organizer
  第63回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] アストロサイトの貪食作用はミクログリア機能不全を補完する2020
- Author(s)
  小西博之、岡本峻幸、佐藤克明、木山博資
- Organizer
  第80回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] ミクログリア貪食能低下はアストロサイトにより補完される2020
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第125回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] 末梢神経の発達や恒常性維持における末梢神経内マクロファージの機能解析2019
- Author(s)
  大迫史佳、小西博之、木山博資
- Organizer
  第9回生理学研究所・名古屋大学医学系研究科　合同シンポジウム
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] ミクログリア貪食能不全はアストロサイトにより補完される2019
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第79回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] Astrocytic phagocytosis as a compensated function of microglial dysfunction2019
- Author(s)
  Konishi H, Kiyama H
- Organizer
  XIV European Meeting on Glial Cell Function in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] アストロサイトによるミクログリア貪食作用の補完性2019
- Author(s)
  小西博之、木山博資
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] Complementarity between microglia and astrocytes in phagocytosis2019
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第42回日本神経科学大会・第62回日本神経化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-19K06904
[Presentation] ミクログリアの貪食能低下はアストロサイトにより補完される2019
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第124回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Astrocytic phagocytic activity compensates for microglial dysfunction2019
- Author(s)
  Hiroyuki Konishi
- Organizer
  第11回Nagoyaグローバルリトリート
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] ミクログリア除去時に現れるアストロサイトの貪食能2018
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第78回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] ミクログリア除去モデルマウスにおけるミクログリア残骸のアストロサイトによる貪食2018
- Author(s)
  小西博之、岡本峻幸、佐藤克明、木山博資
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会　合同年会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] GPR34はミクログリアにおける炎症性反応を惹起し神経障害性疼痛を増悪させる2018
- Author(s)
  佐世暁、小西博之、小林正明、日比英晴、青木淳賢、木山博資
- Organizer
  第40回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Phagocytic clearance of microglial debris by astrocytes in microglial depletion model mice2018
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第22回グリア研究会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] 脳シナプトソームに集積している枝分かれしたシアル酸化N結合型糖鎖はシグレックHと相互作用する2018
- Author(s)
  吉村武、半田麻衣、小西博之、深田優子、真鍋良幸、田中克典、Guangming Bao、木山博資、深瀬浩一、池中一裕
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会　合同年会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Siglec-Hのミクログリアマーカーとしての有用性と機能2018
- Author(s)
  小西博之、小林正明、佐藤克明、木山博資
- Organizer
  第123回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] ミクログリア除去時に現れるアストロサイトの貪食能2018
- Author(s)
  小西博之、木山博資
- Organizer
  第8回生理学研究所・名古屋大学医学系研究科　合同シンポジウム
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] 脊髄後角のミクログリアに発現する GPR34 は神経障害性疼痛を悪化させる2018
- Author(s)
  佐世暁、小西博之、小林正明、日比英晴、青木淳賢、木山博資
- Organizer
  第8回生理学研究所・名古屋大学医学系研究科　合同シンポジウム
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Microglial debris are phagocytosed by astrocytes under absence of functional microglia2017
- Author(s)
  小西博之、佐藤克明、木山博資
- Organizer
  第22回グリア研究会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] ミクログリアマーカーSiglec-Hの発現特性と機能2017
- Author(s)
  小西博之、木山博資
- Organizer
  第7回名古屋大学医学系研究科・生理学研究所合同シンポジウム
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Siglec-H is a specific marker for microglia in mice2017
- Author(s)
  小西博之、小林正明、佐藤克明、木山博資
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] ミクログリアマーカーSiglec-Hの発現特性と機能2017
- Author(s)
  小西博之、小林正明、佐藤克明、木山博資
- Organizer
  第77回日本解剖学会中部支部学術集会
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] 先天性関節拘縮症の原因遺伝子としてのDINEと軸索再生におけるミトコンドリアダイナミクス2016
- Author(s)
  木山博資, 松本早紀子、永田健一、玉田宏美、時實恭平、小西博之、桐生寿美子
- Organizer
  第17回ORIGIN 神経科学研究会
- Place of Presentation
  まつや千千（福井県・あわら市）
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-16H05117
[Presentation] TREM2/DAP12 を介する神経損傷後のミクログリア活性化2016
- Author(s)
  小西博之、小林正明、木山博資
- Organizer
  第6回生理学研究所・名古屋大学医学系研究科合同シンポジウム
- Place of Presentation
  名古屋大学医学部（愛知県名古屋市）
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] TREM2/DAP12 signal in microglia exacerbates neuropathic pain2016
- Author(s)
  小西博之、小林正明、木山博資
- Organizer
  第21回グリア研究会
- Place of Presentation
  千里ライフセンター（大阪府豊中市）
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] TREM2/DAP12を介するミクログリア活性化は神経障害性疼痛を増悪させる2016
- Author(s)
  小西博之、小林正明、高井俊行、木山博資
- Organizer
  第59回日本神経化学会大会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Alteration of phospholipid localization induces microglial ramification2016
- Author(s)
  Tokizane K, Konishi H, Makide K, Kawana H, Nakamuta S, Kaibuchi K, Ohwada T, Aoki J, Kiyama H
- Organizer
  Cold Spring Harbor Asia Conferences, New insights into Glia function & Dysfunction
- Place of Presentation
  World Hotel Grand Dushulake Suzhou (Suzhou, China)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07055
[Presentation] Augmentation of neuropathic pain by DAP12 mediated signal in microglia2015
- Author(s)
  Konishi H, Kobayashi M, Takai T, Kiyama H
- Organizer
  XII European Meeting on Glial Cell Function in Health and Disease
- Place of Presentation
  Bilbao, Spain
- Year and Date
  2015-07-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] 6-sialyl-lewisc on n-glycan may be involved in microglial phagocytosis of neuron2015
- Author(s)
  Handa M, Yoshimura T, Torii T, Konishi H, Kiyama H, Ikenaka K
- Organizer
  25th Biennial Meeting of the International Society for Neurochemistry
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] A DAP12-dependent signal promotes pro-Inflammatory polarization in microglia following nerve injury and exacerbates degeneration of injured neurons2015
- Author(s)
  Kobayashi M, Konishi H, Takai T, Kiyama H
- Organizer
  XII European Meeting on Glial Cell Function in Health and Disease
- Place of Presentation
  Bilbao, Spain
- Year and Date
  2015-07-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] DAP12を介した神経損傷後のミクログリア活性化2014
- Author(s)
  小西博之、小林正明、高井俊行、木山博資
- Organizer
  第119回日本解剖学会総会全国学術総会
- Place of Presentation
  自治医科大学（下野市）
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] 持続的ストレス負荷により下垂体のメラノトロフに発現するVGFとその発現制御2013
- Author(s)
  時實恭平、小西博之、安井正佐也、小川登紀子、佐々木一樹、南野直人、木山博資
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  京都国際会館（京都市）
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] Siglec-H is an anti-inflammatory molecule expressed in microglia in response to nerve injury2013
- Author(s)
  Kobayashi M, Konishi H, Kiyama H
- Organizer
  Neuro2013　（第56回日本神経化学会総会）
- Place of Presentation
  京都国際会館、京都
- Data Source
  KAKENHI-PLANNED-23111007
[Presentation] ミクログリアの抗炎症作用機序-神経損傷反応性に発現するSiglec-Hについて2013
- Author(s)
  小林正明、小西博之、木山博資
- Organizer
  第56回日本神経化学会大会
- Place of Presentation
  京都国際会館（京都市）
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] PAP-Ш(Reg-IIIγ)は N 末端切断により線維状構造を形成し軸検索伸長の足場となる2011
- Author(s)
  小西博之、松本早紀子、木山博資
- Organizer
  第54回日本神経化学大会
- Place of Presentation
  山代温泉瑠璃光、石川
- Data Source
  KAKENHI-PROJECT-22390035
[Presentation] PAP-III(Reg-2)はN末端切断により線維状構造を形成し軸索伸長の足場となる2011
- Author(s)
  小西博之、松本早紀子、川原慎一、前田理亜、木山博資
- Organizer
  第88回日本生理学会大会・第116回日本解剖学会総会・全国学術集会
- Place of Presentation
  横浜コンベンションセンター(横浜)
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] PAP-III (Reg-IIIgamma)はN末端切断により線維状構造を形成し軸索伸長の足場となる2011
- Author(s)
  小西博之、松本早紀子、木山博資
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光(金沢)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] PAP-IIIはN末端切断により線維状構造を形成し軸索伸長の足場となる2011
- Author(s)
  小西博之、松本早紀子、木山博資
- Organizer
  第2回名古屋大学医学部・生理学研究所合同シンポジウム
- Place of Presentation
  名古屋大学(名古屋)
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] PAP-III(Reg-IIIgamma)はN末端切断により線維状構造を形成し軸索伸長の足場となる2011
- Author(s)
  小西博之、松本早紀子、木山博資
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  瑠璃光(金沢)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] マウス個体発生におけるレクチン様タンパクReg-IIIβとReg-IIIγの発現解析2011
- Author(s)
  松本早紀子、小西博之、前田理亞、木山博資
- Organizer
  第88回日本生理学会大会・第116回日本解剖学会総会・全国集会合同大会
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-22390035
[Presentation] PAP-IIIはN末端切断により線維状構造を形成する2010
- Author(s)
  小西博之、松本早紀子、木山博資
- Organizer
  第12回ORIGIN夏のワークショプ
- Place of Presentation
  レイクフォレストリゾート(京都)
- Year and Date
  2010-09-05
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] The pancreatitis-associated protein-III (PAP-III) is polymerized into a fibrillar structure by the cleavage of its N-terminus2010
- Author(s)
  小西博之
- Organizer
  Society for Neuroscience 40th Annual Meeting
- Place of Presentation
  San Diego Convention Center (米国サンディエゴ)
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] Pancreatitis-associated protein-III (PAP-III)はN末端切断により線維状構造を形成する2010
- Author(s)
  小西博之
- Organizer
  第33回日本神経科学大会・第53回日本神経化学会大会・第20回日本神経回路学会大会・合同大会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] Thepancreatit is-associated protein-III(PAP-III) is polymerized into a fibrillarstructure by the cleavage of its N-terminus2010
- Author(s)
  Konishi H, Matsumoto S, Kawahara S, Maeda R, Kiyama H
- Organizer
  Society for Neuroscience 40thAnnual Meeting
- Place of Presentation
  San Diego Convention Center(San Diego), USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] Pancreatitis-associated protein-III(PAP-III)はN末端切断により線維状構造を形成する2010
- Author(s)
  小西博之、川原慎一、松本早紀子、前田理亜、木山博資
- Organizer
  第33回日本神経科学大会・第53回日本神経化学会大会・第20回日本神経回路学会大会・合同大会
- Place of Presentation
  神戸コンベンションセンター(神戸)
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22700398
[Presentation] 脳外傷後におけるPAP/Regファミリー分子の発現解析2008
- Author(s)
  安保恵一、鈴木了暢、小西博之、木山博資
- Organizer
  第113回日本解剖学会
- Place of Presentation
  大分医科大学、大分
- Data Source
  KAKENHI-PROJECT-19209005
[Presentation] 脳外傷後におけるPAP/Regファミリー分子の発現解析2008
- Author(s)
  安保恵一、鈴木了暢、小西博之、木山博資
- Organizer
  日本解剖学会、第113回総会全国学術集会
- Place of Presentation
  大分大学・医学部構内
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19209005
[Presentation] ミクログリアが形成する脳内環境と損傷運動ニューロンの運命
- Author(s)
  小西博之、小林正明、木山博資
- Organizer
  第120回日本解剖学会総会・全国学術集会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] ミクログリアDAP12による炎症反応は神経損傷後の神経細胞死を増悪させる
- Author(s)
  小林正明、小西博之、高井俊行、木山博資
- Organizer
  第37回日本神経科学学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] 神経損傷後のミクログリア活性化制御因子
- Author(s)
  小西博之、小林正明、木山博資
- Organizer
  第37回日本神経科学学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25830050
[Presentation] 神経損傷後のミクログリア活性化制御因子
- Author(s)
  小西博之,小林正明,木山博資
- Organizer
  第37回日本神経科学学会
- Place of Presentation
  パシフィコ横浜　（神奈川県、横浜市）
- Year and Date
  2014-09-11 – 2014-09-13
- Invited
- Data Source
  KAKENHI-PLANNED-23111007

1. KIYAMA Hiroshi (00192021)

# of Collaborated Projects: 5 results

# of Collaborated Products: 26 results
2. KIRYU Sumiko (70311529)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
3. NAKAGOMI Saya (60423894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 前田光代 (40122080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 濤川一彦 (50312468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. ITO kengo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. OGAWA Tokiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. TACHIBANA Yoshihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 祖父江元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 大河原美静

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 青木淳賢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 大野欽司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 玉田宏美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 高井俊行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 善本隆之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Konishi Hiroyuki 小西 博之

KONISHI Hiroyuki 小西 博之

Research Projects

Research Products

Co-Researchers

グリアとリンパ管のインターラクションによる脳病態制御Principal Investigator

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脳損傷後に起こる硬膜リモデリングのメカニズムと意義Principal Investigator

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Origin and function of macrophages in the peripheral nervous systemPrincipal Investigator

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Effects of a DAP12-mediated signal on microglial activation after injuryPrincipal Investigator

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Organelle dynamics for fate determination of injured neurons

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Expression and function of Siglec-H in the nervous systemPrincipal Investigator

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Functional consequences of glia-neuron interactions in degenerating and regenerating neurons

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An involvement of damage induced neuronal endopeptidase DINE in construction of neuro-muscular junction.

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Analyses of N-terminal processing of secretory lectin PAP-III in neuronal regenerationPrincipal Investigator

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Identification of a transcription factor complex which promotes nerve regeneration

Principal Investigator

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グリア・ニュ ロン相互作用による神経機能維持メカニズムとその加齢変化の解析

Principal Investigator

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[Journal Article] Repeated cold stress, an animal model for fibromyalgia, elicits proprioceptor-induced chronic pain with microglial activation in mice2024

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[Journal Article] Phagocytic astrocytes: Emerging from the shadows of microglia2022

Author(s)

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Konishi Hiroyuki 小西博之

KONISHI Hiroyuki 小西博之

グリア・ニュロン相互作用による神経機能維持メカニズムとその加齢変化の解析