NABEYAMA Wataru 鍋山航

Researcher Number	90448952
Affiliation (based on the past Project Information) *help	2008: 学習院大学, 理学部・化学科, 客員研究員 2007: 学習院大学, 理学部, 客員研究員
Review Section/Research Field	Except Principal Investigator Chemistry related to living body
Keywords	Except Principal Investigator インデノピラゾール / 内皮細胞増殖因子受容体 / HIF-1α / チロシンキナーゼ / シグナル伝達 / 阻害剤 / 癌 / 蛋白質 / ポストゲノム創薬

Development of Tyrosine Kinase Inhibitors Based on the Structures of Target Protein
- Principal Investigator
  
  NAKAMURA Hiroyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Gakushuin University

All 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] de novo Design and Synthesis of N-Benzylanilines as New Candidates for VEGFR Tyrosine Kinase Inhibitors,Org.2008
- Author(s)
  M.Uno, H.S.Ban, W.Nabeyama, H.Nakamura
- Journal Title
  
  Biomol. Chem 6
  
  Pages: 979-981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18350090
[Journal Article] de novo Design and Synthesis of N-Benzylanilines as New Candidates for VEGFR Tyrosine Kinase Inhibitors2008
- Author(s)
  M. Uno, H. S. Ban, W. Nabeyama, H. Nakamura
- Journal Title
  
  Org. Biomol. Chem. 6
  
  Pages: 979-981
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18350090
[Journal Article] Allene as an Alternative Functional Group for DrugDesign : Effect of C-C Multiple Bonds Conjugated with Quinazolines on EGFR Tyrosine Kinase Inhibition2008
- Author(s)
  H.S.Ban, S.Onagi, M.Uno, W.Nabeyama, H.Nakamura
- Journal Title
  
  ChemMedChem 3
  
  Pages: 1094-1103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18350090
[Journal Article] Allene as an Alternative Functional Group for Drug Design : Effect of C-C Multiple Bonds Conjugated with Quinazolines on EGFR Tyrosine Kinase Inhibition2008
- Author(s)
  H. S. Ban, S. Onagi, M. Uno, W. Nabeyama, H. Nakamura
- Journal Title
  
  ChemMedChem 3
  
  Pages: 1094-1103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18350090
[Journal Article] Selective Inhibition of EGFR and VEGER Tyrosine Kinases Controlled by a Boronic Acid Substituent on 4-Anilinoquinazolines2006
- Author(s)
  Nakamura, H.; Usui, T.; Horikoshi, R.; Nabeyama, W.; Ban, H.S.
- Journal Title
  
  YAKUGAKU ZASSHI 126
  
  Pages: 164-165
- Data Source
  KAKENHI-PROJECT-18350090
[Journal Article] Selective Inhibition of EGFR and VEGER Tyrosine Kinases Controlled by a Boronic Acid Substituent on 4-Anilinoquinazolines2006
- Author(s)
  Nakamura, H. Usui, T. Horikoshi, R. Nabeyama, W. Ban, H. S.
- Journal Title
  
  YAKUGAKU ZASSHI 126
  
  Pages: 164-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] ホウ素含有4-アニリノキナゾリンによるEGFRチロシンキナーゼ持続的抑制作用2009
- Author(s)
  鍋山航, 臼井大晃, 潘鉉承, 中村浩之
- Organizer
  日本薬学会第129 回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] ホウ素含有4-アニリノキナゾリンによるEGFRチロシンキナーゼ持続的抑制作用2009
- Author(s)
  鍋山航、臼井大晃、潘鉉承、中村浩之
- Organizer
  日本薬学会第129回年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] de novo分子設計法を用いた血管内皮増殖因子受容体チロシンキナーゼ阻害剤の開2008
- Author(s)
  宇野正治、潘鉉承、鍋山航、中村浩之
- Organizer
  日本薬学会第128回年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] 4-アニリノキナゾリン骨格におけるホウ素置換部位によるチロシンキナーゼ選択的阻害活性2007
- Author(s)
  Ban Hyun Seung、堀越良爾、鍋山航、中村浩之
- Organizer
  日本薬学会第127回年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] アレニルキナゾリン化合物の合成と生物活性評価2007
- Author(s)
  鍋山航、小名木信耶、Ban Hyun Seung、中村浩之
- Organizer
  日本薬学会第127回年会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] 新しいホウ素デリバリーシステムにむけた基礎的研究とJRR4における動物実験の実際2007
- Author(s)
  中井啓、山本哲哉、鶴淵隆、吉田文代、鶴田和太郎、松田真秀、松村明、上野学、丸山美菜子、鍋山航、潘鉱承、中村浩之、新保敬史、金田安史、藤井仁、李千萬
- Organizer
  第4回日本中性子捕捉療法学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] ynthesis of Boron Containing Quinazolines2006
- Author(s)
  中村浩之、臼井大晃、堀越良爾、鍋山航、潘鉉承
- Organizer
  Unprecedented Control of Inhibitions toward EGFR and VEGFR2 Protein Tyrosine Kinases by a Boronic Acid Substituent
- Place of Presentation
  サンファン(プエルトリコ)
- Data Source
  KAKENHI-PROJECT-18350090
[Presentation] 第28回生体膜と薬物の相互作用シンポジウム、4-アニリノキナゾリン骨格へのホウ酸基導入によるEGFRおよびVEGFRチロシンキナーゼ阻害活性制御2006
- Author(s)
  中村浩之、臼井大晃、堀越良爾、鍋山航、潘鉉承
- Organizer
  第28回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-18350090

1. NAKAMURA Hiroyuki (30274434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. BAN Hyonsun (60433710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results

NABEYAMA Wataru 鍋山 航

Research Projects

Research Products

Co-Researchers

Development of Tyrosine Kinase Inhibitors Based on the Structures of Target Protein

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] de novo Design and Synthesis of N-Benzylanilines as New Candidates for VEGFR Tyrosine Kinase Inhibitors,Org.2008

Author(s)

Journal Title

Data Source

[Journal Article] de novo Design and Synthesis of N-Benzylanilines as New Candidates for VEGFR Tyrosine Kinase Inhibitors2008

Author(s)

Journal Title

Data Source

[Journal Article] Allene as an Alternative Functional Group for DrugDesign : Effect of C-C Multiple Bonds Conjugated with Quinazolines on EGFR Tyrosine Kinase Inhibition2008

Author(s)

Journal Title

Data Source

[Journal Article] Allene as an Alternative Functional Group for Drug Design : Effect of C-C Multiple Bonds Conjugated with Quinazolines on EGFR Tyrosine Kinase Inhibition2008

Author(s)

Journal Title

Data Source

[Journal Article] Selective Inhibition of EGFR and VEGER Tyrosine Kinases Controlled by a Boronic Acid Substituent on 4-Anilinoquinazolines2006

Author(s)

Journal Title

Data Source

[Journal Article] Selective Inhibition of EGFR and VEGER Tyrosine Kinases Controlled by a Boronic Acid Substituent on 4-Anilinoquinazolines2006

Author(s)

Journal Title

Data Source

[Presentation] ホウ素含有4-アニリノキナゾリンによるEGFRチロシンキナーゼ持続的抑制作用2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ホウ素含有4-アニリノキナゾリンによるEGFRチロシンキナーゼ持続的抑制作用2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] de novo分子設計法を用いた血管内皮増殖因子受容体チロシンキナーゼ阻害剤の開2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 4-アニリノキナゾリン骨格におけるホウ素置換部位によるチロシンキナーゼ選択的阻害活性2007

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] アレニルキナゾリン化合物の合成と生物活性評価2007

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 新しいホウ素デリバリーシステムにむけた基礎的研究とJRR4における動物実験の実際2007

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ynthesis of Boron Containing Quinazolines2006

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 第28回生体膜と薬物の相互作用シンポジウム、4-アニリノキナゾリン骨格へのホウ酸基導入によるEGFRおよびVEGFRチロシンキナーゼ阻害活性制御2006

Author(s)

Organizer

Place of Presentation

Data Source

NABEYAMA Wataru 鍋山航