Takahashi Hidekazu 高橋秀和

… Alternative Names

Researcher Number	90450402
Other IDs
Affiliation (Current)	2019: 岡山理科大学, 獣医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2018: 山口大学, 大学院医学系研究科, 講師 2013 – 2016: 山口大学, 医学(系)研究科(研究院), 講師 2015: 山口大学, 医学系研究科, 講師 2013: 山口大学, 医学系研究科, 講師 2013: 山口大学, 大学院・医学系研究科, 講師 … More
Review Section/Research Field	Principal Investigator Hygiene and public health / Genetics/Genome dynamics / Hygiene Except Principal Investigator Biological Sciences / Hygiene / Hygiene and public health / Laboratory medicine
Keywords	Principal Investigator 免疫学 / 疫学 / 遺伝子 / 遺伝学 / アセチル化 / ミトコンドリア / SOD / 活性酸素 / 翻訳後修飾 / 分裂酵母 … More Except Principal Investigator バイオマーカー / メチル化 / S-アデノシルメチオニン / 線虫 / S-adenosylmethionine / アセチルCoA / 転写 / LC-MS/MS / メチオニン代謝 / 栄養 / 寿命 / -adenosylmethionine / ストレス耐性 / 老化 / 予防医学 / アレルギー / アルギナーゼ / 喘息 / 糖尿病 / 肥満 / 一酸化窒素 / アルギナーゼI / L-アルギニン / 酸化ストレス / 呼気NO / IgE / インスリン / アルギニン / 炎症バイオマーカー / hsCRP / ELISA / 非ウイルス性肝がん / microRNA / エクソソーム / ctDNA / 早期診断 / 非B非C肝がん / マイクロRNA / 骨髄移植 / 遺伝子多型 / 炎症関連因子 / NLRP / インフラマソーム / 移植片対宿主病 / GVHD / 多変量解析 / 遺伝子多型解析 / 骨髄移植後合併症 / SNP Less

Development of method detecting early stage non-viral liver cancer using innate immune factors as new biomarker.Ongoing
- Principal Investigator
  
  田邉剛
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Yamaguchi University
造血幹細胞移植の予後に対するＨＬＡと非ＨＬＡ遺伝子の相互作用の効果の解析Principal InvestigatorOngoing
- Principal Investigator
  
  高橋秀和
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Yamaguchi University
Inhibitory co-receptors as new biomarkers for bone marrow transplantationPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hidekazu
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Yamaguchi University
Development of novel preventive and therapeutic methods for complications after bone marrow transplantation: Genetic analysis and regulation of inflammation-related factors
- Principal Investigator
  
  YAMAGUCHI Natsu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Yamaguchi University
Study on role of protein nitrosylation in the nitric oxide-mediated prevention of asthmaPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hidekazu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Yamaguchi University
  Okayama University
Crosstalk of transcriptional status and amino acid metabolism
- Principal Investigator
  
  FUKAMIZU Akiyoshi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Evaluation of arginase as an inflammatory biomarker.
- Principal Investigator
  
  OGINO Keiki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Okayama University
High-throughput screening for the mitochondrial enzyme that acetylates SODPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Hidekazu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  The Institute of Physical and Chemical Research

All 2018 2017 2014 2013 2012 2011 2009 2008 Other

All Journal Article Presentation

[Journal Article] Associations of interactions between NLRP3 SNPs and HLA mismatch with acute and extensive chronic graft-versus-host diseases2017
- Author(s)
  Hidekazu Takahashi, Naoko Okayama, Natsu Yamaguchi, Yuta Miyahara, Yasuo Morishima, Yutaka Suehiro, Takahiro Yamasaki, Koji Tamada, Satoshi Takahashi, Arinobu Tojo, Shigetaka Asano & Tsuyoshi Tanabe
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 13097-13097
- DOI
  10.1038/s41598-017-13506-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09159, KAKENHI-PROJECT-26460802
[Journal Article] Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population.2017
- Author(s)
  Yamaguchi N, Mahbub MH, Takahashi H, Hase R, Ishimaru Y, Sunagawa H, Amano H, Kobayashi-Miura M, Kanda H, Fujita Y, Yamamoto H, Yamamoto M, Kikuchi S, Ikeda A, Takasu M, Kageyama N, Nakamura M, Tanabe T.
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 22 Pages: 22-35
- DOI
  10.1186/s12199-017-0642-7
- NAID
  210000130210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01821, KAKENHI-PROJECT-17K09159
[Journal Article] The different roles of innate immune receptors in inflammation and carcinogenesis between races2017
- Author(s)
  Natsu Yamaguchi, Yoshimi Suzuki, M. H. Mahbub, Hidekazu Takahashi, Ryosuke Hase, Yasutaka Ishimaru, Hiroshi Sunagawa, Rie Watanabe, Yoshinobu Eishi, Tsuyoshi Tanabe
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 22 Pages: 70-70
- DOI
  10.1186/s12199-017-0678-8
- NAID
  210000130245
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09159
[Journal Article] Association of plasma free amino acids with hyperuricemia in relation to diabetes mellitus, dyslipidemia, hypertension and metabolic syndrome2017
- Author(s)
  Mahbub MH, Yamaguchi N, Takahashi H, Hase R, Ishimaru Y, Sunagawa H, Amano H, Kobayashi-Miura M, Kanda H, Fujita Y, Yamamoto H, Yamamoto M, Kikuchi S, Ikeda A, Kageyama N, Nakamura M, Tanabe T
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 1-12
- DOI
  10.1038/s41598-017-17710-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01821, KAKENHI-PROJECT-17K09159
[Journal Article] Inflammatory airway responses by nasal inoculation of suspended particulate matter in NC/Nga mice.2014
- Author(s)
  Ogino K, Takahashi N, Kubo M, Takeuchi A, Nakagiri M, Fujikura Y
- Journal Title
  
  Environ Toxicol
  
  Volume: (in press) Pages: 642-654
- DOI
  10.1002/tox.21791
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390163, KAKENHI-PROJECT-26670331
[Journal Article] Association of serum arginase I with L-arginine, 3-nitrotyrosine, and exhaled nitric oxide in healthy Japanese workers.2014
- Author(s)
  Ogino K, Wang DH, Kubo M, Obase Y, Setiawan H, Yan F, Takahashi H, Zhang R, Tsukiyama Y, Yoshida J, Zou Y
- Journal Title
  
  Free radical research
  
  Volume: Vol. 48 Pages: 137-145
- DOI
  10.3109/10715762.2013.842979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390163
[Journal Article] Comparison of serum ferritin and oxidative stress biomarkers between Japanese workers with and without metabolic syndrome.2014
- Author(s)
  Iwanaga S, Sakano N, Taketa K, Takahashi N, Wang DH, Takahashi H, Kubo M, Miyatake N, Ogino K
- Journal Title
  
  Obes Res Clin Pract
  
  Volume: (in press) Pages: 271-282
- DOI
  10.1016/j.orcp.2013.01.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390163, KAKENHI-PROJECT-26293152
[Journal Article] Relationship between ceruloplasmin and oxidative biomarkers including ferritin among healthy Japanese2013
- Author(s)
  Inoue Kiyomi, Ogino Keiki; Sakano Noriko; Wang　Da-Hong; Yoshida Junko; Akazawa Yuji; Kanbara Sakiko; Kubo Masayuki; Takahashi Hidekazu
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 52(2) Issue: 2 Pages: 160-166
- DOI
  10.3164/jcbn.12-122
- NAID
  130004466707
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792295, KAKENHI-PROJECT-23390163
[Journal Article] Evaluation of serum arginase I as an oxidative stress biomarker in a healthy Japanese population using a newly established ELISA2013
- Author(s)
  Ogino K, Murakami I, Wang DH, Tsukiyama Y, Takahashi H, Kubo M, Sakano N, Setiawan H, Bando M, Ohmoto Y
- Journal Title
  
  Clinical Biochemistry
  
  Volume: Vol. 46 Pages: 1717-1722
- DOI
  10.1016/j.clinbiochem.2013.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390163
[Journal Article] Anti-inflammatory effect of arginase inhibitor and corticosteroid on airway allergic reactions in a Dermatophogoides farinae-induced NC/Nga mouse model.2013
- Author(s)
  Ogino K, Kubo M, Takahashi H, Zhang R, Zou Y, Fujikura Y
- Journal Title
  
  Inflammation
  
  Volume: Vol. 36 Pages: 141-151
- DOI
  10.1007/s10753-012-9529-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390163, KAKENHI-PROJECT-24790587
[Journal Article] Inhibition of arginase ameliorates experimental ulcerative colitis in mice.2013
- Author(s)
  Akazawa Y, Kubo M, Zhang R, Matsumoto K, Yan F, Setiawan H, Takahashi H, Fujikura Y, Ogino K
- Journal Title
  
  Free radical research
  
  Volume: Vol. 47 Pages: 137-145
- DOI
  10.3109/10715762.2012.756980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390163
[Journal Article] Evaluation of urinary hydrogen peroxide as an oxidative stress biomarker in a healthy Japanese population2013
- Author(s)
  Sato Yoshie; Ogino Keiki; Sakano Noriko; Wang,Da-Hong; Yoshida Junko; Akazawa Yuji; kanbara Sakiko; Inoue Kiyomi; Kubo Masayuki; Takahashi Hidekazu
- Journal Title
  
  Free Radical Research
  
  Volume: 47(3) Pages: 181-191
- DOI
  10.3109/10715762.2012.759218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792295, KAKENHI-PROJECT-23390163
[Presentation] 非血縁骨髄移植の予後とインフラマソーム遺伝子多型との関連2018
- Author(s)
  髙橋秀和、岡山直子、山口奈津、宮原悠太、MH Mahbub、長谷亮佑、森島泰雄、末廣寛、山﨑隆弘、玉田耕治、高橋聡、東條有伸、浅野茂隆、田邉剛
- Organizer
  第40回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-26460802
[Presentation] 自然免疫関連疾患の発症機構2017
- Author(s)
  田邉剛、高橋秀和、山口奈津、長谷亮佑、Hossain Mahbub
- Organizer
  第16回分子予防環境医学研究会
- Place of Presentation
  熊本市国際交流会館
- Year and Date
  2017-02-03
- Data Source
  KAKENHI-PROJECT-25860408
[Presentation] Functional analysis for histidine protein methyltransferase in Caenorhabditis elegans.2013
- Author(s)
  Ishihara, S., Hirota, K., Kako, K., Tanaka, Y., Daitoku, H. Takahashi, Y. and Fukamizu, A.
- Organizer
  International Symposium on Transcription and Metabolism
- Place of Presentation
  兵庫（淡路夢舞台国際会議場）
- Data Source
  KAKENHI-PLANNED-23116004
[Presentation] S-adenosyl-L-methionine synthetase-1 (SAMS-1) regulates short-term-starvation-induced lifespan extension in Caenorhabditis elegans2013
- Author(s)
  Sakuta, G., Hirota, K., Takahashi, Y., Daitoku, H. Kako, K. and Fukamizu, A.
- Organizer
  International Symposium on Transcription and Metabolism
- Place of Presentation
  兵庫（淡路夢舞台国際会議場）
- Data Source
  KAKENHI-PLANNED-23116004
[Presentation] 職業従事者におけるストレスに関するスコアと生活習慣及び血液バイオマーカーとの関連性についての検討2013
- Author(s)
  三宅優紀, 髙橋秀和, 久保正幸, 汪達紘, 佐藤美恵, 吉田純子, 張燃, 築山依果, 鄒宇, 舟久保徳美, 叶欽霞, 石井香代子, 井上清美, 荻野景規
- Organizer
  第86回日本産業衛生学会学術総会
- Place of Presentation
  愛媛県
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] 職業従事者におけるストレスに関するスコアと生活習慣及び血液バイオマーカーとの関連性についての検討2013
- Author(s)
  三宅優紀, 高橋秀和, 久保正幸, 汪達紘, 佐藤美恵, 吉田純子, 張燃, 築山依果, 鄒宇, 舟久保徳美, 叶欽霞, 石井香代子, 井上清美, 荻野景規
- Organizer
  第86回日本産業衛生学会学術総会
- Place of Presentation
  ひめぎんホール (愛媛)
- Year and Date
  2013-05-17
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] 肥満マウスモデルにおける血中アルギナーゼ活性およびアルギニン量の変化2013
- Author(s)
  高橋秀和, 中田信也, 張燃, ヘリ・セティアワン, 村上育郎, 久保正幸, 荻野景規
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス (石川)
- Year and Date
  2013-03-25
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] 健診受診者における尿中過酸化水素について2012
- Author(s)
  佐藤美恵, 荻野景規, 坂野紀子, 汪達紘, 吉田純子, 赤澤裕二, 神原咲子, 井上清美, 久保正幸, 高橋秀和
- Organizer
  第10回日本予防医学会学術総会
- Place of Presentation
  広島大学霞キャンパス広仁会館 (広島)
- Year and Date
  2012-11-25
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] 企業健診受診者における酸化ストレスバイオマーカーと動脈硬化および冠動脈疾患リスクについて2012
- Author(s)
  佐藤美恵, 荻野景規, 坂野紀子, 汪達紘, 吉田純子, 赤澤裕二, 神原咲子, 井上清美, 久保正幸, 高橋秀和
- Organizer
  第56回中国四国合同産業衛生学会
- Place of Presentation
  岡山大学創立五十周年記念館 (岡山)
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] 企業従事者における抗酸化炎症バイオマーカーセルロプラスミンに関する研究2012
- Author(s)
  井上清美, 坂野紀子, 佐藤美恵, 汪達紘, 久保正幸, 高橋秀和, 宮武伸行, 荻野景規
- Organizer
  第56回中国四国合同産業衛生学会
- Place of Presentation
  岡山大学創立五十周年記念館 (岡山)
- Year and Date
  2012-12-09
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] セルロプラスミンは抗酸化炎症バイオマーカーの一種か?2012
- Author(s)
  井上清美, 坂野紀子, 佐藤美恵, 久保正幸, 汪達紘, 高橋秀和, 宮武伸行, 荻野景規
- Organizer
  第10回日本予防医学会学術総会
- Place of Presentation
  広島大学霞キャンパス広仁会館 (広島)
- Year and Date
  2012-11-25
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] Asymmetric arginine dimethylation determines lifespan in Caenorhabditis elegans by regulating 　forkhead transcription factor DAF-162012
- Author(s)
  Takahashi, Y.
- Organizer
  第33回内藤カンファレンス
- Place of Presentation
  シャトレーゼ　ガトーキングダム　サッポロ
- Year and Date
  2012-06-27
- Data Source
  KAKENHI-PLANNED-23116004
[Presentation] 健康成人及び喘息患者における血清3-nitrotyrosine の疫学的評価2011
- Author(s)
  荻野景規, 高橋紀子, ヘリ・セティアワン, 赤澤裕二, 高橋秀和, 汪達紘
- Organizer
  第17回MPO 研究会シンポジウム
- Place of Presentation
  アークホテル熊本(熊本)
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23390163
[Presentation] 分裂酵母のミトコンドリアSODの翻訳後修飾の解析2009
- Author(s)
  高橋秀和, 鈴木健裕, 白井温子, 松山晃久, 堂前直, 吉田稔
- Organizer
  酵母遺伝学フォーラム第42回研究報告会
- Place of Presentation
  つくば日本
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20770009
[Presentation] 分裂酵母のミトコンドリアSODの翻訳後修飾の解析2009
- Author(s)
  高橋秀和
- Organizer
  酵母遺伝学フォーラム第42回研究報告会
- Place of Presentation
  つくば市
- Year and Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-20770009
[Presentation] Screening for the mitochondrial SOD acetyltransferase2008
- Author(s)
  Takahashi H., Shirai A., Matsuyama A., Yoshida M
- Organizer
  1st RIKEN Chemical Biology Department International Symposium
- Place of Presentation
  Atami, Japan
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-20770009
[Presentation] Asymmetric Arginine Dimethylation Determines Lifespan in C. elegans by Regulating Forkhead Transcription Factor DAF-16.
- Author(s)
  Takahashi, Y.
- Organizer
  18th International C. elegans Meeting
- Place of Presentation
  アメリカ合衆国・ロサンゼル
- Data Source
  KAKENHI-PLANNED-23116004
[Presentation] 肥満マウスモデルにおける血中アルギナーゼ活性およびアルギニン量の変化
- Author(s)
  髙橋秀和
- Organizer
  第83回日本衛生学会学術総会
- Place of Presentation
  金沢大学鶴間キャンパス(石川県）
- Data Source
  KAKENHI-PROJECT-23390163

1. TANABE Tsuyoshi (80260678)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. YAMAGUCHI Natsu (40450671)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. FUKAMIZU Akiyoshi (60199172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. DAITOKU Hiroaki (30361314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. HIROTA Keiko (00375370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. OGINO Keiki (70204104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
7. WANG Da-hong (90294404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
8. KUBO Masayuki (60420519)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
9. OUCHI Kazunobu (80351899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OBASE Yasushi (40399762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MATSUI Hideki (30157234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TOJO Arinobu (00211681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. 玉田耕治 (00615841)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. KANBARA Sakiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. MIURA Mikiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Takahashi Hidekazu 高橋 秀和

TAKAHASHI Hidekazu 高橋 秀和

Research Projects

Research Products

Co-Researchers

Development of method detecting early stage non-viral liver cancer using innate immune factors as new biomarker.Ongoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

造血幹細胞移植の予後に対するＨＬＡと非ＨＬＡ遺伝子の相互作用の効果の解析Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Inhibitory co-receptors as new biomarkers for bone marrow transplantationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel preventive and therapeutic methods for complications after bone marrow transplantation: Genetic analysis and regulation of inflammation-related factors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on role of protein nitrosylation in the nitric oxide-mediated prevention of asthmaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Crosstalk of transcriptional status and amino acid metabolism

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Evaluation of arginase as an inflammatory biomarker.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

High-throughput screening for the mitochondrial enzyme that acetylates SODPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Associations of interactions between NLRP3 SNPs and HLA mismatch with acute and extensive chronic graft-versus-host diseases2017

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[Journal Article] Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population.2017

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NAID

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[Journal Article] The different roles of innate immune receptors in inflammation and carcinogenesis between races2017

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NAID

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[Journal Article] Association of plasma free amino acids with hyperuricemia in relation to diabetes mellitus, dyslipidemia, hypertension and metabolic syndrome2017

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[Journal Article] Inflammatory airway responses by nasal inoculation of suspended particulate matter in NC/Nga mice.2014

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Takahashi Hidekazu 高橋秀和

TAKAHASHI Hidekazu 高橋秀和