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Ooi Kazuhiro  大井 一浩

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OOI Kazuhiro  大井 一浩

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Researcher Number 90451450
Affiliation (Current) 2025: 金沢大学, 附属病院, 講師
Affiliation (based on the past Project Information) *help 2016 – 2024: 金沢大学, 附属病院, 講師
2015: 金沢大学, 大学病院, 講師
Review Section/Research Field
Principal Investigator
Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Except Principal Investigator
Basic Section 20010:Mechanics and mechatronics-related / Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry
Keywords
Principal Investigator
STR/Ortマウス / STR/ortマウス / 進行性下顎頭吸収 / 選択的軟骨破壊抑制 / 改変型TIMP-3 / 変形性顎関節症 / アグリカネーゼ / CBAマウス / 抑制効果 / 下顎頭軟骨破壊 … More / [-1A]TIMP-3 / 発症抑制 / 発症メカニズム / マウスモデル / 発症原因 / 病態 / 野生型Str/Ortマウス / 保護 / 下顎頭軟骨 / [-1A] TIMP-3 / アグリカナーゼ / TMJ-OA / STR / Ortマウス / -1AlaTIMP3 / PSG / CT / 上気道通気状態 / 顎矯正手術 / 気道 / 睡眠時咬筋活動 / 周術期管理 / ポリソムノグラフィー / 睡眠呼吸障害 / 気道通気状態 / 顎変形症 … More
Except Principal Investigator
骨切削 / 顎変形症手術 / 時系列解析 / 振動モニタリング / 小児 / OSA / 流体解析 / 原因部位 / CT値 / CT / CFD / 閉塞性睡眠時無呼吸 / 口蓋扁桃 / 小児OSAS / 睡眠呼吸モデル / 小児OSAS / 3次元モデル / 小児OSA Less
  • Research Projects

    (7 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (8 People)
  •  ベイズモデリングによるデータ同化と位相的データ解析を用いた顎骨切削手術技能評価

    • Principal Investigator
      中野 寛
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 20010:Mechanics and mechatronics-related
    • Research Institution
      Tokyo Institute of Technology
  •  Development of an osteotomy surgery support system by geometric analysis of auditory-tactile fusion data

    • Principal Investigator
      Nakano Yutaka
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 20010:Mechanics and mechatronics-related
    • Research Institution
      Tokyo Institute of Technology
  •  Inhibition for progressive mandibular condylar resorption by selective cartilage destruction inhibition using modified TIMP-3Principal Investigator

    • Principal Investigator
      Ooi Kazuhiro
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kanazawa University
  •  Identification of the causative site of pediatric OSA using physical properties of peri-airway tissue calculated from CT values

    • Principal Investigator
      IWASAKI Tomonori
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      The University of Tokushima
  •  Elucidation of the pathophysiology and cause of progressive mandibular condylar resorptionPrincipal Investigator

    • Principal Investigator
      Ooi Kazuhiro
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Kanazawa University
  •  The identification of the cause site of pediatric OSAS by the three-dimensional sleep breath model built using new technology

    • Principal Investigator
      Iwasaki Tomonori
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthodontics/Pediatric dentistry
    • Research Institution
      Kagoshima University
  •  Evaluation of perioperative obstructive sleep apnea in patient with dentofacial deformityPrincipal Investigator

    • Principal Investigator
      OOI Kazuhiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kanazawa University

All 2023 2022 2021 2019 2017

All Journal Article Presentation

  • [Journal Article] Metalloelastase-12 is involved in the temporomandibular joint inflammatory response as well as cartilage degradation by aggrecanases in STR/Ort mice2021

    • Author(s)
      Yamashita-futani Yoko、Jokaji Rei、Ooi Kazuhiro、Kobayashi Kazuhiko、Kanakis Ioannis、Liu Ke、Kawashiri Shuichi、Bou-gharios George、Nakamura Hiroyuki
    • Journal Title

      Biomedical Reports

      Volume: 14 Issue: 6 Pages: 1-8

    • DOI

      10.3892/br.2021.1427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09764, KAKENHI-PROJECT-21K10135
  • [Presentation] Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice2023

    • Author(s)
      1.Kazuhiro Ooi, Yutaka Kobayashi, Kazuhiro Yamamoto, Ioannis Kanakis, Yoko Yamashita, Takao Sakai, Fadi Jarad, Hiroyuki Nakamura, George Bou-Gharios, Shuichi Kawashiri
    • Organizer
      Cutting Edge Osteoarthritis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10135
  • [Presentation] Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice2023

    • Author(s)
      3.Kazuhiro Ooi, Yutaka Kobayashi, Kazuhiro Yamamoto, Ioannis Kanakis, Yoko Yamashita, Takao Sakai, Fadi Jarad, Hiroyuki Nakamura, Shuichi Kawashiri, George Bou-Gharios
    • Organizer
      European Society for Temporomandibular Joint Surgeons meeting 2023
    • Data Source
      KAKENHI-PROJECT-21K10135
  • [Presentation] 回転切削器具の振動モニタリングによる顎変形症手術支援に関する研究(スペクトル平均による軟質層到達判定精度の評価)2023

    • Author(s)
      中野 寛、吉田 尚史、大井 一浩、高原 弘樹
    • Organizer
      Dynamics and Design Conference 2023
    • Data Source
      KAKENHI-PROJECT-21H01273
  • [Presentation] 遺伝子改変STR/Ortマウスを用いた変形性顎関節症の病態解明と発症抑制の試み2022

    • Author(s)
      大井一浩
    • Organizer
      第35回一般社団法人日本顎関節学会総会・学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K10135
  • [Presentation] Targeted inhibition of aggrecanases inhibits the progression of age-dependent cartilage degradation in a temporomandibular joint in the STR/Ort mice2022

    • Author(s)
      Yutaka Kobayashi1,2, Kazuhiro Yamamoto1, Ioannis Kanakis3, Akinobu Kawano2, Yoko Yamashita2, Takao Sakai4, Fadi Jarad5, Hiroyuki Nakamura6, Shuichi Kawashiri2, George Bou-Gharios1, Kazuhiro Ooi2.
    • Organizer
      Cutting Edge Osteoarthritis Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K10135
  • [Presentation] Temporomandibular joint osteoarthritis in the STR/Ort mouse model of spontaneous osteoarthritis and effect of targeted inhibition of aggrecanases for mandibular condylar cartilage degradation2019

    • Author(s)
      Kazuhiro Ooi, Ioannis Kanakis, Yoko Yamashita, Hiroyuki Nakamura, Shuichi Kawashiri, George Bou-Gharios
    • Organizer
      American Society for Temporomandibular Joint Surgeon Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09764
  • [Presentation] Effect of targeted inhibition of aggrecanases for mandibular condylar cartilage degradation in the STR/Ort spontaneous mouse model of temporomandibular joint osteoarthritis2019

    • Author(s)
      OOI K, KANAKIS I, YAMASHITA Y, IDE K, FUTANI Y, KOBAYASHI Y, KOBAYASHI K, JOKAJI R, NAKAMURA H, YAMAMOTO K, SAKAI T, BOU-GHARIOS G, KAWASHIRI S
    • Organizer
      The 6th Asian Academy congress for TMJ
    • Data Source
      KAKENHI-PROJECT-18K09764
  • [Presentation] 下顎前突症患者における周術期の閉塞性睡眠呼吸障害の評価とその予測因子2017

    • Author(s)
      大井一浩,定梶嶺,井手健太郎,大矢明日香,小林泰,野口夏代,加藤広禄,中村博幸,川尻秀一
    • Organizer
      日本口腔外科学会総会
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] 全身麻酔下で埋伏智歯抜歯術を行った骨格性顎変形症患者の術前後における睡眠相の変化2017

    • Author(s)
      小林泰、 大井一浩, 麸谷 圭昭, 井手 健太郎2, 定梶 嶺
    • Organizer
      日本睡眠歯科学会総会
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] PERIOPERATIVE EVALUATION AND MANAGEMENT OF OBSTRUCTIVE SLEEP APNEA AFTER MANDIBULAR SETBACK BY SAGGITAL SPLITTING RAMUS OSTEOTOMY2017

    • Author(s)
      R. Jokaji, K. Ooi, K. Ide, M. Ishimiya, Y. Kobayashi, H. Kitahara, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
    • Organizer
      International Conference of Oral and Maxillofacial Surgery 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEAUSING PERIPHERAL ARTERIAL TONOMETRY DURING PERIOPERATIVE PERIOD AFTER REMOVAL OF IMPACTED THIRD MOLAR WITH DENTOFACIAL DEFOTMITY IN GENERAL ANETHESIA2017

    • Author(s)
      Y. Kobayashi, K. Ooi, R. Jyokaji, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, N. Nakata, T. Kasahara, S. Kawashiri
    • Organizer
      International conference for oral and maxillofacial surgery 2017
    • Place of Presentation
      香港
    • Year and Date
      2017-03-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEA AND SLEEP QUALITY IN PATIENTS WITH SKELETAL CLASS Ⅲ MALOCCLUSION2017

    • Author(s)
      K. Ooi, R. Jokaji, K. Ide, Y. Kobayashi, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
    • Organizer
      International Conference on Oral and Maxillofacial Surgery 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] 簡易型睡眠評価装置を用いた顎矯正手術の周術期における睡眠呼吸状態の評価2017

    • Author(s)
      井手 健太郎,大井 一浩,麩谷 圭昭,小林 泰,定梶 嶺
    • Organizer
      日本睡眠歯科学会総会
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEA USING PERIPHERAL ARTERIAL TONOMETRY DURING PERIOPERATIVE PERIOD AFTER REMOVAL OF IMPACTED THIRD MOLAR WITH DENTOFACIAL DEFOTMITY IN GENERAL ANETHESIA2017

    • Author(s)
      Y. Kobayashi, K. Ooi, K. Ide, R. Jokaji, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri,
    • Organizer
      International Conference of Oral and Maxillofacial Surgery 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] PERIOPERATIVE EVALUATION AND MANAGEMENT OF OBSTRUCTIVE SLEEP APNEA AFTER MANDIBULAR SETBACK BY SAGGITAL SPLITTING RAMUS OSTEOTOMY2017

    • Author(s)
      R. Jokaji, K. Ooi, K. Ide, M. Ishimiya, Y. Kobayashi, H. Kitahara, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
    • Organizer
      International conference for oral and maxillofacial surgery 2017
    • Place of Presentation
      香港
    • Year and Date
      2017-03-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11310
  • [Presentation] EVALUATION OF OBSTRUCTIVE SLEEP APNEA AND SLEEP QUALITY IN PATIENTS WITH SKELETAL CLASS Ⅲ MALOCCLUSION2017

    • Author(s)
      K. Ooi, R. Jokaji, K. Ide, Y. Kobayashi, N. Noguchi, K. Katoh, H. Nakamura, S. Takamichi, M. Nakata, K. Kasahara, S. Kawashiri
    • Organizer
      International conference for oral and maxillofacial surgery 2017
    • Place of Presentation
      香港
    • Year and Date
      2017-03-31
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K11310
  • 1.  Iwasaki Tomonori (10264433)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  Nakano Yutaka (70433068)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  中村 博幸 (30542253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 4.  山崎 要一 (30200645)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  原 浩貴 (90274167)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  原田 みずえ (20585103)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  大廣 洋一 (40301915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  格口 渉 (70740645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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