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Komekado Hideyuki  米門 秀行

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KOMEKADO Hideyuki  米門 秀行

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Researcher Number 90452359
Affiliation (Current) 2025: 京都大学, 医学研究科, 非常勤講師
Affiliation (based on the past Project Information) *help 2014: 京都大学, 医学(系)研究科(研究院), その他
2012 – 2014: 京都大学, 医学(系)研究科(研究院), 非常勤講師
2008 – 2011: Kyoto University, 医学研究科, 助教
Review Section/Research Field
Principal Investigator
Gastroenterology
Keywords
Principal Investigator
胃癌 / ナルディライジン / 抗癌剤 / 大腸癌 / 微小環境 / シェディング / 胃 / 癌 / 上部消化管学 / 上部消化管学(食道、胃、十二指腸) … More / Stat3 / Wntシグナル / 下部消化管学 / 消化管Wntシグナル / 下部消化管学(小腸・大腸) Less
  • Research Projects

    (3 results)
  • Research Products

    (6 results)
  •  Therapeutic strategy against gastrointestinal cancers targeting nardilysinPrincipal Investigator

    • Principal Investigator
      KOMEKADO Hideyuki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Roles of nardilysin and ADAM proteases in the regulation of gastric cancer cell growth.Principal Investigator

    • Principal Investigator
      KOMEKADO Hideyuki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University
  •  Regulation of Wnt signaling by activated innate immunity in intestinal epithelium.Principal Investigator

    • Principal Investigator
      KOMEKADO Hideyuki
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyoto University

All 2014 2012 2011 2010

All Journal Article Presentation

  • [Journal Article] Deletion of nardilysin prevents the development of steatohepatitis and liver fibrosis.2014

    • Author(s)
      Ishizu-Higashi S, Seno H, Nishi E, Matsumoto Y, Ikuta K, Tsuda M, Kimura Y, Takada Y, Kimura Y, Nakanishi Y, Kanda K, Komekado H, Chiba T.
    • Journal Title

      Plos One

      Volume: 9 Issue: 5 Pages: e98017-e98017

    • DOI

      10.1371/journal.pone.0098017

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590914, KAKENHI-PROJECT-24659363, KAKENHI-PUBLICLY-25112707, KAKENHI-PUBLICLY-25130706, KAKENHI-PROJECT-25860533, KAKENHI-PUBLICLY-26116715, KAKENHI-PROJECT-26293068, KAKENHI-PROJECT-26293173, KAKENHI-PROJECT-26670139
  • [Journal Article] Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signaling via enhanced ectodomain shedding of TNF-a2012

    • Author(s)
      Kanda K, Komekado H, Kawada M, et al
    • Journal Title

      EMBO Molecular Medicine

      Volume: (印刷中) Issue: 5 Pages: 396-411

    • DOI

      10.1002/emmm.201200216

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J40033, KAKENHI-PROJECT-10J02434, KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-22790641, KAKENHI-PUBLICLY-23122510, KAKENHI-PROJECT-23300117, KAKENHI-PROJECT-23590937, KAKENHI-PROJECT-23659154, KAKENHI-PROJECT-23659755, KAKENHI-PROJECT-24590914, KAKENHI-PROJECT-24659363, KAKENHI-PROJECT-24700366, KAKENHI-PUBLICLY-23117519, KAKENHI-PUBLICLY-24113713
  • [Presentation] ナルディライジンはTNF-αのシェディングを促進し内因性サイトカインシグナル経路を活性化して胃癌細胞の増殖を制御する2011

    • Author(s)
      神田啓太郎、米門秀行、妹尾浩、千葉勉、西英一郎
    • Organizer
      第70回日本癌学会総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2011-11-03
    • Data Source
      KAKENHI-PROJECT-22790641
  • [Presentation] ナルディライジンによるIL-6/Stat3シグナルを介した胃癌細胞の増殖制御2010

    • Author(s)
      神田啓太郎、米門秀行、妹尾浩、千葉勉、西英一郎
    • Organizer
      第69回日本癌学会総会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22790641
  • [Presentation] ナルディライジンによるIL-6/Stat3シグナルを介した胃癌細胞の増殖制御2010

    • Author(s)
      神田啓太郎、米門秀行、妹尾浩、千葉勉、西英一郎
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(口演)
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-22790641
  • [Presentation] マウス内視鏡モデルを用いた新規大腸粘膜傷害・再生モデルの検討2010

    • Author(s)
      秋武玲子、神田啓太郎、米門秀行、河田真由美、妹尾浩、千葉勉
    • Organizer
      第51回日本消化器病学会大会
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2010-10-15
    • Data Source
      KAKENHI-PROJECT-20790492

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