OOE Hidekazu 大栄秀和

Researcher Number	90452979
Affiliation (based on the past Project Information) *help	2008 – 2011: Sapporo Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Experimental pathology Except Principal Investigator General surgery
Keywords	Principal Investigator follistatin / 小型肝細胞 / 肝再生 / 癌幹細胞 / 癌 / 再生医学 Except Principal Investigator 細胞相互作用 / 組織化 / 遺伝子導入 / 再生医学 … More / 組織形成 / 移植 / 幹・前駆細胞 / 肝臓 / 3次元培養 / 胆管形成 / CD44 / 成熟化 / 小型肝細胞 / 人工肝臓 / 肝発生 / 肝組織形成 / 分化 / 増殖 / 細胞移植 / 肝幹・前駆細胞 / 肝再生 Less

Basic research for the production of human hepatocytes and the transplantation of hepatic tissues
- Principal Investigator
  
  MITAKA Toshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Sapporo Medical University
Gene expression analysis in small hepatocytes and cancer stem cells for searching cancer related genes.Principal Investigator
- Principal Investigator
  
  OOE Hidekazu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Experimental pathology
- Research Institution
  Sapporo Medical University

All 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 「各種肝病態における肝オーバル細胞・小型肝細胞の同定」再生医学叢書第5巻、第5章肝細胞の機能制御・分化誘導2012
- Author(s)
  市戸義久、大栄秀和、谷水直樹、三高俊広
- Publisher
  朝倉書店(印刷中)
- Data Source
  KAKENHI-PROJECT-21390365
[Journal Article] Growth ability and repopulation efficiency of transplanted hepatic stem, progenitor cells, and mature hepatocytes in retrorsine-treated rat livers2012
- Author(s)
  Ichinohe N, Kon J, Sasaki K, Nakamura Y, Ooe H, Tanimizu N, Mitaka T
- Journal Title
  
  Cell Transplant
  
  Volume: 21 Issue: 1 Pages: 11-22
- DOI
  10.3727/096368911x580626
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390365, KAKENHI-PROJECT-22790385, KAKENHI-PROJECT-22790386
[Journal Article] Proliferation of rat small hepatocytes depends on follistatin expression2012
- Author(s)
  Ooe H, Chen Q, Kon J, Sasaki K, Miyoshi H, Ichinohe N, Tanimizu N, Mitaka T
- Journal Title
  
  J Cell Physiol
  
  Volume: 227 Issue: 6 Pages: 2363-2370
- DOI
  10.1002/jcp.22971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390365, KAKENHI-PROJECT-22390259, KAKENHI-PROJECT-22790385, KAKENHI-PROJECT-22790386, KAKENHI-PROJECT-24390304, KAKENHI-PROJECT-24790389
[Journal Article] Drug Metabolism Reviews focusing on drug transporter interactions in the liver : Characterization of hepatic-organoid cultures2010
- Author(s)
  Mitaka T, Ooe H
- Journal Title
  
  Drug Metab Rev
  
  Volume: 42 Issue: 3 Pages: 472-481
- DOI
  10.3109/03602530903492020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390365
[Journal Article] Drug Metabolism Reviews focusing on drug transporter interactions in the liver : Characterization of hepatic-organoid cultures2010
- Author(s)
  Mitaka T, Ooe H.
- Journal Title
  
  Drug Metab Rev 42
  
  Pages: 472-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890179
[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes.2009
- Author(s)
  Ooe H, Kon J, Oshima J, Mitaka T
- Journal Title
  
  Drug Metabol Dispos 37
  
  Pages: 1963-1969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890179
[Journal Article] Thy1-positive cells have bipotential ability to differentiate into hepatocytes and biliary epithelial cells in galactosamine-induced rat liver regeneration.2009
- Author(s)
  Kon J, Ichinohe N, Ooe H, Chen Q, Sasaki K, Mitaka T
- Journal Title
  
  Am J Pathol 175(6)
  
  Pages: 2362-2371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890179
[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes2009
- Author(s)
  Ooe H, Kon J, Oshima H, Mitaka T
- Journal Title
  
  Drug Metabol Dispos
  
  Volume: 37 Issue: 9 Pages: 1963-1969
- DOI
  10.1124/dmd.108.022905
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390365
[Journal Article] 肝臓における幹細胞2009
- Author(s)
  市戸義久、今純子、大栄秀和、三高俊広
- Journal Title
  
  肝胆膵
  
  Volume: 59巻4号 Pages: 573-580
- Data Source
  KAKENHI-PROJECT-21390365
[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes2009
- Author(s)
  Ooe H, et al.
- Journal Title
  
  Drug Metabol Dispos 37
  
  Pages: 1963-1969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890179
[Journal Article] Thy1-positive cells have bipotential ability to differentiate into hepatocytes and biliary epithelial cells in galactosamine-induced rat liver regeneration2009
- Author(s)
  Kon J, Ichinohe N, Ooe H, Chen Q, Sasaki K, Mitaka T
- Journal Title
  
  Am J Pathol
  
  Volume: 175(6) Pages: 2362-2371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390365
[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes2009
- Author(s)
  Ooe H, et al.
- Journal Title
  
  Drug Metabol Dispos 37
  
  Pages: 1963-1969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390365
[Journal Article] 肝臓における幹細胞.2009
- Author(s)
  市戸義久、今純子、大栄秀和、三高俊広
- Journal Title
  
  肝胆膵 59巻4号
  
  Pages: 573-580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890179
[Journal Article] Drug Metabolism Reviews focusing on drug transporter interactions in the liver: Characterization of hepatic-organoid cultures.
- Author(s)
  Mitaka T, Ooe H
- Journal Title
  
  Drug Metab Rev (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の増殖機序2011
- Author(s)
  大栄秀和
- Organizer
  第18回肝細胞研究会
- Place of Presentation
  東京ガーデンパレス
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21390365
[Presentation] Thy1陽性未分化肝幹細胞の分化機序の解析2010
- Author(s)
  市戸義久、大栄秀和、中村幸雄、今純子、三高俊広
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島市
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の増殖における Follistatin/Activin の役割2009
- Author(s)
  大栄秀和, 他
- Organizer
  第89回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌市
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21390365
[Presentation] Thy1/CD44両陽性肝前駆細胞の分化機序の解析2009
- Author(s)
  市戸義久、今純子、大栄秀和、中村幸雄、三高俊広
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸、肝臓(Supplement)
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の増殖における Follistatin/Activin の役割2009
- Author(s)
  大栄秀和, 他
- Organizer
  第89回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌市
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の増殖機序の解析2009
- Author(s)
  大栄秀和、市戸義久、三高俊広
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸市
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] Thy1/CD44両陽性肝前駆細胞の分化機序の解析2009
- Author(s)
  市戸義久、今純子、大栄秀和、中村幸雄、三高俊広
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-05
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の増殖機序の解析2009
- Author(s)
  大栄秀和, 他
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  神戸市
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-21390365
[Presentation] ラット小型肝細胞の増殖におけるFollistatin/Activinの役割2009
- Author(s)
  大栄秀和、陳其潔、今純子、三高俊広
- Organizer
  第89回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌市
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] 肝前駆細胞の分化機序の解析2009
- Author(s)
  市戸義久、今純子、大栄秀和、中村幸雄、三高俊広
- Organizer
  第98回日本病理学会総会
- Place of Presentation
  京都
- Year and Date
  2009-05-02
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] Thy1/CD44両陽性肝前駆細胞の分化機序の解析2009
- Author(s)
  市戸義久、今純子、大栄秀和、中村幸雄、三高俊広
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形市
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-21390365
[Presentation] Thy1/CD44両陽性肝前駆細胞の分化機序の解析2009
- Author(s)
  市戸義久、今純子、大栄秀和、中村幸雄、三高俊広
- Organizer
  第89回北海道医学大会腫瘍系分科会
- Place of Presentation
  札幌市
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] Thy1/CD44両陽性肝前駆細胞の分化機序の解析2009
- Author(s)
  市戸義久、今純子、大栄秀和、中村幸雄、三高俊広
- Organizer
  第16回肝細胞研究会
- Place of Presentation
  山形市
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の成熟化による遺伝子発現変動の解析2008
- Author(s)
  大栄秀和, 他
- Organizer
  第15回肝細胞研究会
- Place of Presentation
  静岡市
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット肝前駆細胞の増殖および成熟化における遺伝子発現の網羅的解析2008
- Author(s)
  大栄秀和, 他
- Organizer
  第44回日本肝臓学会総会
- Place of Presentation
  松山市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット肝前駆細胞の成熟化による肝細胞機能遺伝子及び増殖関連遺伝子の発現変動解析2008
- Author(s)
  大栄秀和、陳其潔、今純子、市戸義久、三高俊広
- Organizer
  第88回北海道医学大会腫瘍系分科会
- Place of Presentation
  旭川市
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] ラット小型肝細胞の成熟化による肝細胞機能遺伝子および増殖関連遺伝子の発現変動解析2008
- Author(s)
  大栄秀和, 他
- Organizer
  第88回北海道医学大会腫瘍系分科会
- Place of Presentation
  旭川市
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-20890179
[Presentation] 肝障害モデルラットにおけるOval細胞の分化機構の解析2008
- Author(s)
  市戸義久、今純子、大栄秀和、三高俊広
- Organizer
  第88回北海道医学大会病理系分科会
- Place of Presentation
  札幌市
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-20890179

1. MITAKA Toshihiro (50231618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. TANIMIZU Naoki (00333386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. ICHINOHE Norihisa (80452978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. MIZUGUCHI Toru (30347174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HIRATA Koichi (50136959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIKKAWA Yamato (20274227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANISHITA Kazuo (10101776)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OOE Hidekazu 大栄 秀和

Research Projects

Research Products

Co-Researchers

Basic research for the production of human hepatocytes and the transplantation of hepatic tissues

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene expression analysis in small hepatocytes and cancer stem cells for searching cancer related genes.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「各種肝病態における肝オーバル細胞・小型肝細胞の同定」再生医学叢書第5巻、第5章肝細胞の機能制御・分化誘導2012

Author(s)

Publisher

Data Source

[Journal Article] Growth ability and repopulation efficiency of transplanted hepatic stem, progenitor cells, and mature hepatocytes in retrorsine-treated rat livers2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Proliferation of rat small hepatocytes depends on follistatin expression2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drug Metabolism Reviews focusing on drug transporter interactions in the liver : Characterization of hepatic-organoid cultures2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drug Metabolism Reviews focusing on drug transporter interactions in the liver : Characterization of hepatic-organoid cultures2010

Author(s)

Journal Title

Data Source

[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Thy1-positive cells have bipotential ability to differentiate into hepatocytes and biliary epithelial cells in galactosamine-induced rat liver regeneration.2009

Author(s)

Journal Title

Data Source

[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes2009

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 肝臓における幹細胞2009

Author(s)

Journal Title

Data Source

[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes2009

Author(s)

Journal Title

Data Source

[Journal Article] Thy1-positive cells have bipotential ability to differentiate into hepatocytes and biliary epithelial cells in galactosamine-induced rat liver regeneration2009

Author(s)

Journal Title

Data Source

[Journal Article] Thyroid hormone is necessary for expression of constitutive androstane receptor in rat hepatocytes2009

Author(s)

Journal Title

Data Source

[Journal Article] 肝臓における幹細胞.2009

Author(s)

Journal Title

Data Source

[Journal Article] Drug Metabolism Reviews focusing on drug transporter interactions in the liver: Characterization of hepatic-organoid cultures.

Author(s)

Journal Title

Data Source

[Presentation] ラット小型肝細胞の増殖機序2011

Author(s)

Organizer

Place of Presentation

OOE Hidekazu 大栄秀和