Furukawa Ayako 古川亜矢子

… Alternative Names

古川亜矢子フルカワアヤコ

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Researcher Number	90453050
Other IDs
Affiliation (Current)	2025: 京都大学, 農学研究科, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 京都大学, 農学研究科, 准教授 2021 – 2022: 横浜市立大学, 生命医科学研究科, 特任助教 2017: 横浜市立大学, その他の研究科, その他 2016: 横浜市立大学, 生命医科学研究科, 特任助教 2015: 横浜市立大学, 生命医科学, 特任助教 2014: 公益財団法人サントリー生命科学財団, その他部局等, 研究員 2010: Yokohama City University, その他
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 43040:Biophysics-related / Complex systems / Functional biochemistry / Structural biochemistry
Keywords	Principal Investigator 溶液NMR / 動的な相互作用 / ヒストンテイル / ヌクレオソーム / 動的構造解析 / NMR / 天然変性領域 / リンカーヒストンH1 / ヒストン / ヘテロクロマチンタンパク質HP1α … More / 液液相分離 / HP1α / 相関構造解析 / 液-液相分離 / ヘテロクロマチン / DNAのメチル化 / 酵素反応 / リアルタイムNMR / DNAメチル化 / 蛋白質の動的構造解析 / 酵素の調節機構 / タンパク質の動的構造解析 / 酵素 Less

Elucidation of dynamic interactions between histone tails and DNA in chromatosome.Principal Investigator
- Principal Investigator
  
  古川亜矢子
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kyoto University
Elucidation of phase separation mechanism of HP1a by phosphorylationPrincipal Investigator
- Principal Investigator
  
  Furukawa Ayako
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
  Yokohama City University
Elucidation of dynamic interactions of histone tails with nucleosomal DNA or linker DNAPrincipal Investigator
- Principal Investigator
  
  古川亜矢子
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Yokohama City University
インプリント遺伝子のDNAメチル化模様を制御するDnmt3aの過渡的複合体Principal Investigator
- Principal Investigator
  
  古川亜矢子
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Yokohama City University
Regulation of heme oxygenase-2 activity elucidated by the analysis of structural dynamicsPrincipal Investigator
- Principal Investigator
  
  Furukawa Ayako
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Yokohama City University
  Suntory Foundation for Life Sciences
HIV感染阻害宿主因子APOBEC3Gを生かした新規抗HIV薬の開発基盤の確立Principal Investigator
- Principal Investigator
  
  古川亜矢子
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Yokohama City University

All 2023 2022 2021 2016 2014 Other

All Journal Article Presentation

[Journal Article] H2A Ubiquitination Alters H3-tail Dynamics on Linker-DNA to Enhance H3K27 Methylation2023
- Author(s)
  Ohtomo H., Ito S., McKenzie NJ., Uckelmann M., Wakamori M., Ehara H., Furukawa A., Tsunaka Y., Shibata M., Sekine S., Umehara T., Davidovich C., Koseki H. *Nishimura Y.
- Journal Title
  
  J. Mol. Biol.
  
  Volume: 435 Issue: 4 Pages: 167936-167936
- DOI
  10.1016/j.jmb.2022.167936
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H05756
[Journal Article] Histone tail network and modulation in a nucleosome2022
- Author(s)
  Tsunaka Yasuo、Furukawa Ayako、Nishimura Yoshifumi
- Journal Title
  
  Current Opinion in Structural Biology
  
  Volume: 75 Pages: 102436-102436
- DOI
  10.1016/j.sbi.2022.102436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06021, KAKENHI-PUBLICLY-21H05756, KAKENHI-PROJECT-18K06064
[Journal Article] Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome2022
- Author(s)
  Furukawa A., Wakamori M., Arimura Y., Ohtomo H., Tsunaka Y., Kurumizaka H., Umehara T., *Nishimura Y.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 3 Pages: 103937-103937
- DOI
  10.1016/j.isci.2022.103937
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21H05756
[Journal Article] Quantitative analysis of protein–ligand interactions by NMR2016
- Author(s)
  Furukawa A., Konuma T., Yanaka S., Sugase K.
- Journal Title
  
  Progress in Nuclear Magnetic Resonance Spectroscopy
  
  Volume: 96 Pages: 47-57
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01653
[Journal Article] Quantitative analysis of protein–ligand interactions by NMR2016
- Author(s)
  Furukawa A., Konuma T., Yanaka S., Sugase K.,
- Journal Title
  
  Progress in Nuclear Magnetic Resonance Spectroscopy
  
  Volume: 96 Pages: 47-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26840040
[Journal Article] Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy2014
- Author(s)
  Furukawa, A., Sugase, K., Morishita, R., Nagata, T., Kodaki, T., Takaori-Kondo, A., Ryo, A., Katahira, M.
- Journal Title
  
  Angew. Chem. Int. Ed. Engl.
  
  Volume: 53 Issue: 9 Pages: 2349-2352
- DOI
  10.1002/anie.201309940
- NAID
  120005647511
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21113003, KAKENHI-PROJECT-23390110, KAKENHI-PROJECT-23570146, KAKENHI-PUBLICLY-24113710, KAKENHI-PUBLICLY-24121714, KAKENHI-PROJECT-24390115, KAKENHI-PUBLICLY-25115507, KAKENHI-PROJECT-25650056, KAKENHI-PUBLICLY-26104520, KAKENHI-PROJECT-26840040
[Presentation] Elucidation of Dynamic Interactions of Histone H3 N-terminal Tail with DNA in a Nucleosome2023
- Author(s)
  Ayako Furukawa
- Organizer
  2023 Asia-Pacific Nuclear Magnetic Resonance (APNMR) Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04289
[Presentation] ヌクレオソーム中のヒストンH3のN末テイルとDNAとの動的な相互作用の解明2023
- Author(s)
  古川亜矢子
- Organizer
  第16回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04289
[Presentation] 溶液 NMR によるヌクレオソーム中のヒストンテイルの動的構造解析2023
- Author(s)
  古川亜矢子
- Organizer
  第 2 回ゲノムモデリング研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04289
[Presentation] ヌクレオソーム中のヒストンH3のN末テイルとDNAとの動的な相互作用の解明2022
- Author(s)
  古川亜矢子
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05756
[Presentation] リン酸化によるHP1αの液-液相分離機構の解明2022
- Author(s)
  古川亜矢子, 米澤健人, 根上樹, 吉村ゆり子, 林亜紀, 中山潤一, 安達成彦, 千田俊哉, 清水謙多郎, 寺田透, 清水伸隆, 西村善文
- Organizer
  日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-21K06100
[Presentation] ヘテロクロマチン関連タンパク質HP1aのリン酸化による液-液相分離機構の解明2022
- Author(s)
  古川亜矢子, 米澤健人, 根上樹, 吉村ゆり子, 林亜紀, 中山潤一, 安達成彦, 千田俊哉, 清水謙多郎, 寺田透, 清水伸隆, 西村善文
- Organizer
  日本分光学会ＮＭＲ分光部会
- Data Source
  KAKENHI-PROJECT-21K06100
[Presentation] ヌクレオソーム中のヒストンH3のN末テイルとDNAとの動的な相互作用の解明2021
- Author(s)
  古川亜矢子, 若森昌聡, 有村泰宏, 大友秀明, 津中康央,胡桃坂仁志, 梅原崇史, 西村善文
- Organizer
  第39回染色体ワークショップ第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PUBLICLY-21H05756
[Presentation] ヘテロクロマチンタンパク質HP1のNMR構造解析2021
- Author(s)
  古川亜矢子
- Organizer
  BINDS-NMR報告会
- Data Source
  KAKENHI-PROJECT-21K06100
[Presentation] Regulation of heme oxygenase-2 activity elucidated by the analysis of structural dynamics
- Author(s)
  Furukawa A.,, Yamamoto T., Matsuki Y., Suematsu M., Sugase K.
- Organizer
  International Conference on Magnetic Resonance in Biological Systems
- Place of Presentation
  Dallas, USA
- Year and Date
  2014-08-24 – 2014-08-29
- Data Source
  KAKENHI-PROJECT-26840040

1. TSUNAKA Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 菅瀬謙治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Furukawa Ayako 古川 亜矢子

古川 亜矢子 フルカワ アヤコ

Research Projects

Research Products

Co-Researchers

Elucidation of dynamic interactions between histone tails and DNA in chromatosome.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of phase separation mechanism of HP1a by phosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of dynamic interactions of histone tails with nucleosomal DNA or linker DNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

インプリント遺伝子のDNAメチル化模様を制御するDnmt3aの過渡的複合体Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of heme oxygenase-2 activity elucidated by the analysis of structural dynamicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HIV感染阻害宿主因子APOBEC3Gを生かした新規抗HIV薬の開発基盤の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] H2A Ubiquitination Alters H3-tail Dynamics on Linker-DNA to Enhance H3K27 Methylation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histone tail network and modulation in a nucleosome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characteristic H3 N-tail dynamics in the nucleosome core particle, nucleosome, and chromatosome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quantitative analysis of protein&#8211;ligand interactions by NMR2016

Author(s)

Journal Title

Data Source

[Journal Article] Quantitative analysis of protein&#8211;ligand interactions by NMR2016

Author(s)

Journal Title

Data Source

[Journal Article] Quantitative analysis of location- and sequence-dependent deamination by APOBEC3G using real-time NMR spectroscopy2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Elucidation of Dynamic Interactions of Histone H3 N-terminal Tail with DNA in a Nucleosome2023

Author(s)

Organizer

Data Source

[Presentation] ヌクレオソーム中のヒストンH3のN末テイルとDNAとの動的な相互作用の解明2023

Author(s)

Organizer

Data Source

[Presentation] 溶液 NMR によるヌクレオソーム中のヒストンテイルの動的構造解析2023

Author(s)

Furukawa Ayako 古川亜矢子

古川亜矢子フルカワアヤコ

[Journal Article] Quantitative analysis of protein–ligand interactions by NMR2016

[Journal Article] Quantitative analysis of protein–ligand interactions by NMR2016

[Presentation] ヌクレオソーム中のヒストンH3のN末テイルとDNAとの動的な相互作用の解明2021