NAKANO MASAHIRO 中野雅博

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NAKANO Masahiro 中野雅博

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Researcher Number	90456997
Other IDs	https://orcid.org/0000-0003-4247-9008
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所感染病理部, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, 感染病理部, 主任研究官 2022 – 2023: 京都大学, 医生物学研究所, 助教 2016 – 2021: 京都大学, ウイルス・再生医科学研究所, 助教 2017: 京都大学ウイルス, 再生医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Virology Except Principal Investigator Veterinary medical science
Keywords	Principal Investigator 高速原子間力顕微鏡 / インフルエンザウイルス / 二本鎖RNA / 自然免疫 / 原子間力顕微鏡 / リボ核タンパク質複合体 / トゴトウイルス / リボヌクレオタンパク質複合体 / 自然免疫応答 / リボヌクレオタンパク質 … More / 免疫蛍光染色 / マスキング / ライブイメージング / RNAウイルス / 複製 / 転写 … More Except Principal Investigator リコンビナントRNP / RNP / 複製 / 転写 / インフルエンザウイルス Less

Ultrastructural analysis of the Thogoto virus ribonucleoprotein complexPrincipal Investigator
- Principal Investigator
  
  中野雅博
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Japan Institute for Health Security
インフルエンザウイルスが産生する二本鎖RNAとその自然免疫誘導に関する研究Principal Investigator
- Principal Investigator
  
  中野雅博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto University
Masking of double-stranded RNA by the influenza A virus NS1 proteinPrincipal Investigator
- Principal Investigator
  
  Nakano Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kyoto University
Ultrastructural analysis of the virus ribonucleoprotein complexes by high-speed atomic force microsccopyPrincipal Investigator
- Principal Investigator
  
  Nakano Masahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Kyoto University
Toward the live imaging analysis of functional influenza virus RNPs
- Principal Investigator
  
  Keiko Shindo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Cryoelectron microscopic structure of the nucleoprotein?RNA complex of the European filovirus, Lloviu virus2023
- Author(s)
  Hu Shangfan、Fujita-Fujiharu Yoko、Sugita Yukihiko、Wendt Lisa、Muramoto Yukiko、Nakano Masahiro、Hoenen Thomas、Noda Takeshi
- Journal Title
  
  PNAS Nexus
  
  Volume: 2 Issue: 4 Pages: 1-10
- DOI
  10.1093/pnasnexus/pgad120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07052, KAKENHI-PROJECT-22K07086, KAKENHI-PROJECT-22K07099, KAKENHI-PROJECT-22K19431
[Journal Article] Evaluation of Broad Anti-Coronavirus Activity of Autophagy-Related Compounds Using Human Airway Organoids2023
- Author(s)
  Hashimoto Rina、Tamura Tomokazu、Watanabe Yukio、Sakamoto Ayaka、Yasuhara Naoko、Ito Hayato、Nakano Masahiro、Fuse Hiromitsu、Ohta Akira、Noda Takeshi、Matsumura Yasufumi、Nagao Miki、Yamamoto Takuya、Fukuhara Takasuke、Takayama Kazuo
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 20 Issue: 4 Pages: 2276-2287
- DOI
  10.1021/acs.molpharmaceut.3c00114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23KJ1155, KAKENHI-PROJECT-22K07099, KAKENHI-PROJECT-21H03795
[Journal Article] Contribution of RNA-RNA Interactions Mediated by the Genome Packaging Signals for the Selective Genome Packaging of Influenza A Virus.2022
- Author(s)
  Miyamoto S, Muramoto Y, Shindo K, Fujita-Fujiharu Y, Morikawa T, Tamura R, Gilmore JL, Nakano M, Noda T.
- Journal Title
  
  J Virol
  
  Volume: 96 Issue: 6
- DOI
  10.1128/jvi.01641-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22529, KAKENHI-PROJECT-21J12207, KAKENHI-PROJECT-21K20768, KAKENHI-PROJECT-22K07099, KAKENHI-PROJECT-22K19431, KAKENHI-PROJECT-20H03494
[Journal Article] Structural insight into Marburg virus nucleoprotein?RNA complex formation2022
- Author(s)
  Fujita-Fujiharu Yoko、Sugita Yukihiko、Takamatsu Yuki、Houri Kazuya、Igarashi Manabu、Muramoto Yukiko、Nakano Masahiro、Tsunoda Yugo、Taniguchi Ichiro、Becker Stephan、Noda Takeshi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41467-022-28802-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21J12207, KAKENHI-PROJECT-21K06016, KAKENHI-PROJECT-21K07052, KAKENHI-PROJECT-21K07059, KAKENHI-PROJECT-22K07099, KAKENHI-PROJECT-22K19431, KAKENHI-PROJECT-22KK0115, KAKENHI-PROJECT-20H03494, KAKENHI-PROJECT-20H03140
[Journal Article] Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis2022
- Author(s)
  Shinoda Hajime、Iida Tatsuya、Makino Asami、Yoshimura Mami、Ishikawa Junichiro、Ando Jun、Murai Kazue、Sugiyama Katsumi、Muramoto Yukiko、Nakano Masahiro、Kiga Kotaro、Cui Longzhu、Nureki Osamu、Takeuchi Hiroaki、Noda Takeshi、Nishimasu Hiroshi、Watanabe Rikiya
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 473-473
- DOI
  10.1038/s42003-022-03433-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07086, KAKENHI-PROJECT-22K07099, KAKENHI-PROJECT-21H04645, KAKENHI-PROJECT-21K19488, KAKENHI-PLANNED-20H05931, KAKENHI-PROJECT-23K21171
[Journal Article] Migration of Influenza Virus Nucleoprotein into the Nucleolus Is Essential for Ribonucleoprotein Complex Formation2022
- Author(s)
  Sho Miyamoto, Masahiro Nakano, Takeshi Morikawa, Ai Hirabayashi, Ryoma Tamura, Yoko Fujita-Fujiharu, Nanami Hirose, Yukiko Muramoto, and Takeshi Noda
- Journal Title
  
  mBio
  
  Volume: 13 Issue: 1
- DOI
  10.1128/mbio.03315-21
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07575, KAKENHI-PROJECT-19K22529, KAKENHI-PROJECT-20H03494, KAKENHI-PROJECT-21J12207, KAKENHI-PROJECT-21K20768, KAKENHI-PROJECT-22K19431
[Journal Article] CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor2021
- Author(s)
  Takenaga T, Zhang Z, Muramoto Y, Fehling SK, Hirabayashi A, Takamatsu Y, Kajikawa J, Miyamoto S, Nakano M, Urata S, Groseth A, Strecker T, Noda T.
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 9 Pages: 1763-1763
- DOI
  10.3390/v13091763
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06401, KAKENHI-PROJECT-19K07575, KAKENHI-PROJECT-21K07059, KAKENHI-PROJECT-21K20768
[Journal Article] Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis2021
- Author(s)
  Sharma Mahima、Abayakoon Palika、Epa Ruwan、Jin Yi、Lingford James P.、Shimada Tomohiro、Nakano Masahiro、Mui Janice W.-Y.、Ishihama Akira、Goddard-Borger Ethan D.、Davies Gideon J.、Williams Spencer J.
- Journal Title
  
  ACS Central Science
  
  Volume: 7 Issue: 3 Pages: 476-487
- DOI
  10.1021/acscentsci.0c01285
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07575
[Journal Article] Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis2021
- Author(s)
  Masahiro Nakano, Yukihiko Sugita, Noriyuki Kodera, Sho Miyamoto, Yukiko Muramoto, Matthias Wolf, and Takeshi Noda
- Journal Title
  
  Commun. Biol.
  
  Volume: 4 Issue: 1 Pages: 858-858
- DOI
  10.1038/s42003-021-02388-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07575, KAKENHI-PROJECT-19K22529, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-20H03494, KAKENHI-PROJECT-21K07052
[Journal Article] Amplification-free RNA detection with CRISPR?Cas132021
- Author(s)
  Shinoda Hajime、Taguchi Yuya、Nakagawa Ryoya、Makino Asami、Okazaki Sae、Nakano Masahiro、Muramoto Yukiko、Takahashi Chiharu、Takahashi Ikuko、Ando Jun、Noda Takeshi、Nureki Osamu、Nishimasu Hiroshi、Watanabe Rikiya
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 476-476
- DOI
  10.1038/s42003-021-02001-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06401, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PROJECT-19K07575, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-20H05931, KAKENHI-PROJECT-21H04645, KAKENHI-PROJECT-22KJ0608
[Journal Article] Acetylation of the influenza A virus polymerase subunit PA in the N‐terminal domain positively regulates its endonuclease activity2021
- Author(s)
  Hatakeyama Dai、Shoji Masaki、Ogata Seiryo、Masuda Takeshi、Nakano Masahiro、Komatsu Tsugunori、Saitoh Ayaka、Makiyama Kyoko、Tsuneishi Hazuki、Miyatake Asuka、Takahira Mizuki、Nishikawa Erina、Ohkubo Ayana、Noda Takeshi、Kawaoka Yoshihiro、Ohtsuki Sumio、Kuzuhara Takashi
- Journal Title
  
  The FEBS Journal
  
  Volume: 289 Issue: 1 Pages: 231-245
- DOI
  10.1111/febs.16123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06645, KAKENHI-PROJECT-19K05544, KAKENHI-PROJECT-19K07575, KAKENHI-PROJECT-21K06569, KAKENHI-PROJECT-21K07058
[Journal Article] Influenza A virus NS1 optimises virus infectivity by enhancing genome packaging in a dsRNA-binding dependent manner2020
- Author(s)
  Sha Tim Wai、Weber Michaela、Kasumba Dacquin M.、Noda Takeshi、Nakano Masahiro、Kato Hiroki、Fujita Takashi
- Journal Title
  
  Virology Journal
  
  Volume: 17 Issue: 1 Pages: 107-107
- DOI
  10.1186/s12985-020-01357-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07575, KAKENHI-PROJECT-19K22529, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PUBLICLY-19H04831, KAKENHI-PROJECT-20H03494, KAKENHI-ORGANIZER-16H06429
[Journal Article] vRNA-vRNA interactions in influenza A virus HA vRNA packaging.2020
- Author(s)
  Miyamoto, S., Muramoto, Y., Shindo, K., Fujita, Y., Morikawa, T., Tamura, R., Gilmore, J.L., Nakano, M., Noda, T.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2020.01.15.907295
- Open Access
- Data Source
  KAKENHI-PROJECT-19K07575, KAKENHI-PROJECT-19J14928
[Journal Article] Microtubule-dependent transport of arenavirus matrix protein demonstrated using live-cell imaging microscopy.2019
- Author(s)
  Takamatsu Y, Kajikawa J, Muramoto Y, Nakano M, Noda T.
- Journal Title
  
  Microscopy (Oxf)
  
  Volume: 68 Pages: 450-456
- DOI
  10.1093/jmicro/dfz034
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06401, KAKENHI-PROJECT-19K07575, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-19H04831, KAKENHI-PROJECT-18J01631, KAKENHI-PROJECT-19K16666
[Journal Article] Generation of a purely clonal defective interfering influenza virus.2019
- Author(s)
  Yamagata Y, Muramoto Y, Miyamoto S, Shindo K, Nakano M, Noda T.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 63 Issue: 5 Pages: 164-171
- DOI
  10.1111/1348-0421.12681
- NAID
  40021927501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06401, KAKENHI-PROJECT-19K07575, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-17H04082, KAKENHI-PROJECT-17J00495, KAKENHI-PROJECT-19J14928
[Presentation] Influenza A virus circumvents the innate immune response through the concealment of double-stranded RNA2023
- Author(s)
  Masahiro Nakano, Chiho Ohnishi, Yukiko Muramoto, and Takeshi Noda
- Organizer
  第21回あわじ感染と免疫国際フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07099
[Presentation] インフルエンザウイルス二本鎖RNA による自然免疫応答の誘導2022
- Author(s)
  中野　雅博
- Organizer
  第23回生命科学研究科シンポジウム
- Data Source
  KAKENHI-PROJECT-22K07099
[Presentation] Roles of non-structural proteins against production of double-stranded RNA in influenza virus-infected cells2021
- Author(s)
  Masahiro Nakano, S Junichi Kajikawa, Sho Miyamoto, Chiho Ohnishi, Yukiko Muramoto, and Takeshi Noda
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07575
[Presentation] NS1欠損インフルエンザウイルス感染により誘導される二本鎖RNAの合成とその細胞内局在2020
- Author(s)
  中野　雅博，宮本　翔，梶川　純一，村本　裕紀子，野田　岳志
- Organizer
  9th Negative Strand Virus-Japan Symposium
- Data Source
  KAKENHI-PROJECT-19K07575
[Presentation] Identification of amino acid residues of influenza virus NS1 important for masking of double-stranded viral RNAs2019
- Author(s)
  Masahiro Nakano, Sho Miyamoto, Junichi Kajikawa, Yukiko Muramoto, and Takeshi Noda
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07575
[Presentation] Association of the influenza A virus NS1 with double-stranded RNA produced by the ribonucleoprotein complex in vitro2018
- Author(s)
  中野雅博
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08808
[Presentation] Ultrastructure of the influenza virus ribonucleoprotein complexes producing viral RNAs2018
- Author(s)
  Masahiro Nakano
- Organizer
  17th NSV 2018（Verona, Italy）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08808
[Presentation] 原子間力顕微鏡を用いたA型インフルエンザウイルスNS1の二本鎖RNAに対する結合機構の解析2018
- Author(s)
  中野　雅博
- Organizer
  7th Negative Strand Virus-Japan Symposium
- Data Source
  KAKENHI-PROJECT-16K08808
[Presentation] 原子間力顕微鏡を用いたA型インフルエンザウイルスNS1の二本鎖RNAに対する結合機構の解析2018
- Author(s)
  中野雅博
- Organizer
  7th Negative Strand Virus-Japan Symposium
- Data Source
  KAKENHI-PROJECT-16K08808
[Presentation] インフルエンザウイルスRNPが合成するRNAの微細構造解析2017
- Author(s)
  中野　雅博，神道　慶子，野田　岳志
- Organizer
  RNAフロンティアミーティング
- Data Source
  KAKENHI-PROJECT-16K08808
[Presentation] 高速原子間力顕微鏡を用いたインフルエンザウイルスのゲノム転写・複製機構の解明2017
- Author(s)
  中野　雅博
- Organizer
  6th Negative Strand Virus-Japan Symposium
- Place of Presentation
  沖縄
- Year and Date
  2017-01-16
- Data Source
  KAKENHI-PROJECT-16K08808

1. Keiko Shindo (00771312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. KODERA NORIYUKI

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 村本裕紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
4. 野田岳志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 杉田征彦(杉田征彦)

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 葛原隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKANO MASAHIRO 中野 雅博

NAKANO Masahiro 中野 雅博

Research Projects

Research Products

Co-Researchers

Ultrastructural analysis of the Thogoto virus ribonucleoprotein complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

インフルエンザウイルスが産生する二本鎖RNAとその自然免疫誘導に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Masking of double-stranded RNA by the influenza A virus NS1 proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Ultrastructural analysis of the virus ribonucleoprotein complexes by high-speed atomic force microsccopyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Toward the live imaging analysis of functional influenza virus RNPs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cryoelectron microscopic structure of the nucleoprotein?RNA complex of the European filovirus, Lloviu virus2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of Broad Anti-Coronavirus Activity of Autophagy-Related Compounds Using Human Airway Organoids2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contribution of RNA-RNA Interactions Mediated by the Genome Packaging Signals for the Selective Genome Packaging of Influenza A Virus.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural insight into Marburg virus nucleoprotein?RNA complex formation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Migration of Influenza Virus Nucleoprotein into the Nucleolus Is Essential for Ribonucleoprotein Complex Formation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CP100356 Hydrochloride, a P-Glycoprotein Inhibitor, Inhibits Lassa Virus Entry: Implication of a Candidate Pan-Mammarenavirus Entry Inhibitor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis2021

Author(s)

Journal Title

DOI

Data Source

NAKANO MASAHIRO 中野雅博

NAKANO Masahiro 中野雅博