Nakamura Tomomi 中村朝美

Researcher Number	90457490
Other IDs
Affiliation (based on the past Project Information) *help	2021 – 2023: 佐賀大学, 医学部, 助教 2013 – 2019: 佐賀大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Tumor diagnostics / Respiratory organ internal medicine Except Principal Investigator Tumor diagnostics / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator T790M / EGFR-TKI / テーラーメード治療 / Liqud biopsy / 再生検 / 獲得耐性 / 獲得耐性機序 / liquid biopsy / re-biopsy / EGFR-TKI再投与 / T790M再投与 / HGF / 血漿遊離DNA … More Except Principal Investigator … More metastasis / EGFR T790M / 次世代シークエンス / Molecular dynamics / CTOS / PDX / 病的意義不明変異 / がんゲノム / 肺癌 / 液体生検 / circulating tumor DNA / extracellular vesicle / EGFR / circulating free DNA / ｍｏｕｓｅ　ｍｏｄｅｌ / ｍｅｔａｓｔａｓｉｓ / ｐｌａｓｍａ　ＤＮＡ / ＥＧＦＲ　Ｔ７９０Ｍ / mouse model / plasma DNA / 血漿DNA / バイオマーカー / リキッドバイオプシー Less

Cancer comprehensive genomic analysis and establishment of drug efficacy assessment system
- Principal Investigator
  
  Aragane Naoko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Saga University
Basic analysis of characteristics of circulating free DNA on cancer patients
- Principal Investigator
  
  Aragane Naoko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Saga University
Optimization of re-biopsy and liquid biopsy to detect mutations relevant to acquired resistancePrincipal Investigator
- Principal Investigator
  
  Tomomi Nakamura
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Saga University
Analysis how circulating plasma DNA release to peripheral blood and that applies to metastatic animal model using human lung cancer cells
- Principal Investigator
  
  Aragane Naoko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Saga University
A non-invasive system for monitoring molecular markers with plasma DNA for tailored medicunePrincipal Investigator
- Principal Investigator
  
  Nakamura Tomomi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Saga University

All 2023 2022 2019 2018 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer2023
- Author(s)
  Harada Yohei、Sato Akemi、Nakamura Hideaki、Kai Keita、Kitamura Sho、Nakamura Tomomi、Kurihara Yuki、Ikeda Sadakatsu、Sueoka Eisaburo、Kimura Shinya、Sueoka-Aragane Naoko
- Journal Title
  
  BMC Cancer
  
  Volume: 23 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12885-022-10428-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07194, KAKENHI-PROJECT-22K15585
[Journal Article] Absence of copy number gain of <i>EGFR</i> : A possible predictive marker of long‐term response to afatinib2022
- Author(s)
  Nakamura Tomomi、Sato Akemi、Nakashima Chiho、Abe Tomonori、Iwanaga Kentaro、Umeguchi Hitomi、Kawaguchi Atsushi、Sueoka‐Aragane Naoko
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 3 Pages: 1045-1055
- DOI
  10.1111/cas.15655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07194
[Journal Article] Discontinuation due to immune-related adverse events is a possible predictive factor for immune checkpoint inhibitors in patients with non-small cell lung cancer.2019
- Author(s)
  1.Komiya K, Nakamura T, Abe T, Ogusu S, Nakashima C, Takahashi K, Kimura S, Sueoka-Aragane N
- Journal Title
  
  Thorac Cancer.
  
  Volume: 10 Issue: 9 Pages: 1798-1804
- DOI
  10.1111/1759-7714.13149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07197
[Journal Article] Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy2018
- Author(s)
  3.Sato A, Nakashima C, Abe T, Kato J, Hirai M, Nakamura T, Komiya K, Kimura S, Sueoka E, Sueoka-Aragane N
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 61 Pages: 31904-31914
- DOI
  10.18632/oncotarget.25881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07197, KAKENHI-PROJECT-18K07451, KAKENHI-PROJECT-16K09850
[Journal Article] Current Status and Problems of T790M Detection, a Molecular Biomarker of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors, with Liquid Biopsy and Re-biopsy2018
- Author(s)
  5.Komiya K, Nakashima C, Nakamura T, Hirakawa H, Abe T, Ogusu S, Takahashi K, Takeda Y, Egashira Y, Kimura S, Sueoka-Aragane N
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Issue: 6 Pages: 3559-3566
- DOI
  10.21873/anticanres.12628
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07197, KAKENHI-PROJECT-17K07198
[Journal Article] Mechanisms of acquired resistance to afatinib clarified with liquid biopsy.2018
- Author(s)
  1.Nakamura T, Nakashima C, Komiya K, Kitera K, Hirai M, Kimura S, Aragane N.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 12 Pages: e0209384-e0209384
- DOI
  10.1371/journal.pone.0209384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07197
[Journal Article] Automated DNA extraction using cellulose magnetic beads can improve EGFR point mutation detection with liquid biopsy by efficiently recovering short and long DNA fragments2018
- Author(s)
  4.Nakashima C, Sato A, Abe T, Kato J, Hirai M, Nakamura T, Komiya K, Sueoka E, Kimura S, Sueoka-Aragane N
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 38 Pages: 25181-25192
- DOI
  10.18632/oncotarget.25388
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07197, KAKENHI-PROJECT-16K09850
[Journal Article] SPARC is a Possible Predictive Marker for Albumin-bound Paclitaxel in Non-small Cell Lung Cancer2016
- Author(s)
  Komiya K, Nakamura T, Nakashima C, Takahashi K, Umeguchi H, Watanabe N, Sato A, Takeda Y, Kimura S, Sueoka-Aragane N
- Journal Title
  
  Onco Targets Ther
  
  Volume: 9 Pages: 6663-6668
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430144
[Journal Article] Usefulness of plasma HGF level for monitoring acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer2015
- Author(s)
  Umeguchi H, Sueoka-Aragane N, Kobayashi N, Nakamura H, Sato A, Takeda Y, Hayashi S, Sueoka E, Kimura S
- Journal Title
  
  Oncol Rep
  
  Volume: 33 Issue: 1 Pages: 391-6
- DOI
  10.3892/or.2014.3560
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430144
[Presentation] Heat Map Analysis, A New Integrated Pathway Scoring System for Cancer Genome Profiling.2023
- Author(s)
  Nakashima C, Shiotsu Y, Harada Y, Katsuya H, Okuma E, Nishi M, Sato A, Nakamura H, Sueoka-Aragane N.
- Organizer
  AACR Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] Cancer Pathway Index, A new analytical method for cancer genome profiling test, Cancer Pathway Index －包括的がんゲノムプロファイリング検査のための新規解析手法2023
- Author(s)
  中島千穂、小坂井康宏、塩津行正、原田陽平、勝屋弘雄、西正範、中村秀明、佐藤明美、荒金尚子
- Organizer
  第21回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] Cancer Pathway Index, A new analytical method for cancer genome profiling test2023
- Author(s)
  Nakashima C, Shiotsu Y, Kosakai Y, Harada Y, Katsuya H, Nishi M, Sato A, Nakamura H, Sueoka-Aragaen N.
- Organizer
  The 82nd Annual meeting of the Japanese cancer association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] Cancer Pathway Index - がんゲノムプロファイリング検査のためのパスウェイスコアリングシステム.2023
- Author(s)
  中島千穂、小坂井康宏、塩津行正、原田陽平、勝屋弘雄、西正範、中村秀明、佐藤明美、荒金尚子
- Organizer
  第27回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] Liquid biopsyによる肺がんゲノムプロファイリングとEGFRチロシンキナーゼ阻害剤効果予測2022
- Author(s)
  中島千穂、中村朝美、佐藤明美、荒金尚子.
- Organizer
  第63回日本肺癌学会学術集会, 2022.12.1-12.3
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] 当院での胸部悪性腫瘍に対するがんゲノム検査の現状2022
- Author(s)
  中島千穂、瀬戸香織、佐藤明美、中村秀明、梶原心、桑原雄紀、小宮奈津子、小楠真典、中村朝美、荒金尚子
- Organizer
  第89回日本呼吸器学会・日本結核非結核性抗酸菌症学会・日本サルコイドーシス/肉芽腫性疾患学会九州支部秋季学術講演会, 2022.
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] ctDNAを用いた網羅的遺伝子解析によるアファチニブ長期奏効予測因子の検討2022
- Author(s)
  中村朝美、佐藤明美、中島千穂、岩永健太郎、井上周、荒金尚子
- Organizer
  第63回日本肺癌学会学術集会, 2022.12.1-12.3
- Data Source
  KAKENHI-PROJECT-21K07194
[Presentation] 血漿を用いたEGFR-TKIs獲得耐性機序の解明2016
- Author(s)
  中村朝美、小林直美、梅口仁美、小宮一利、木村晋也、荒金尚子
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-26430144
[Presentation] 血漿を用いたafatinib再投与効果予測因子の検討2015
- Author(s)
  中村朝美
- Organizer
  第75回日本呼吸器学会九州支部秋季学術講演会
- Place of Presentation
  佐賀
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたafatinib再投与効果予測因子の検討2015
- Author(s)
  中村朝美
- Organizer
  第55回日本呼吸器学会総会
- Place of Presentation
  東京
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたafatinib再投与効果予測因子の検討2015
- Author(s)
  中村朝美
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  愛媛
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] Potential predictive markers for re-challenge with first generation and second generation EGFR-TKI2015
- Author(s)
  Tomomi Nakamura
- Organizer
  第16回世界肺癌学会
- Place of Presentation
  アメリカ、デンバー
- Year and Date
  2015-09-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたafatinib再投与効果予測因子の検討2015
- Author(s)
  中村朝美、荒金尚子、小宮一利、小林直美、林真一郎、木村晋也
- Organizer
  第55回日本呼吸器学会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-26430144
[Presentation] 血漿を用いたEGFR-TKIs効果予測因子の検討2015
- Author(s)
  中村朝美
- Organizer
  第56回日本肺癌学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討2014
- Author(s)
  中村　朝美
- Organizer
  第54回日本呼吸器学会学術講演会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討2014
- Author(s)
  中村　朝美
- Organizer
  第54回日本肺癌学会九州支部会
- Place of Presentation
  ホルトホール大分
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] EGFR-TKI再投与症例における血漿DNAを用いたEGFR遺伝子変異モニタリング2013
- Author(s)
  中村　朝美
- Organizer
  第54回日本肺癌学会総会
- Place of Presentation
  ホテルニューオータニ東京
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿DNAを用いたEGFR活性化型変異モニタリングシステムの確立2013
- Author(s)
  中村　朝美
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討
- Author(s)
  中村　朝美
- Organizer
  第54回日本呼吸器学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-04-25 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討
- Author(s)
  中村　朝美
- Organizer
  第73回日本呼吸器学会日本結核病学会九州支部秋季学術講演会
- Place of Presentation
  鹿児島県医師会館
- Year and Date
  2014-10-10 – 2014-10-11
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] Non-invasive monitoring system for acquired resistance to EGFR-tyrosine kinase inhibitors using circulating plasma DNA
- Author(s)
  Naoko Sueoka-Aragane, Tomomi Nakamura, Akemi Sato, Naomi Kobayashi, Kentaro Iwanaga, Kazutoshi Komiya, Toshiya Hosomi, Mitsuharu Hirai, Eisaburo Sueoka, Seiji Okada, Shinya Kimura
- Organizer
  73th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  横浜市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26430144
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討
- Author(s)
  中村　朝美
- Organizer
  第55回日本肺癌学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-11-14 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討
- Author(s)
  中村　朝美
- Organizer
  第12回日本臨床腫瘍学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25870518
[Presentation] Usefulness of peripheral blood for monitoring of acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer
- Author(s)
  Naomi Kobayashi, Naoko Sueoka-Aragane, Hitomi Umeguchi, Tomomi Nakamura, Akemi Sato, Kazutoshi Komiya, Yuji Takeda, Shinichiro Hayashi, Eisaburo Sueoka, Shinya Kimura
- Organizer
  American Association for Cancer Research Annual Meeting 2014
- Place of Presentation
  米国サンディエゴ
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26430144
[Presentation] 血漿を用いたEGFR-TKI再投与効果予測因子の検討
- Author(s)
  中村　朝美
- Organizer
  第55回日本肺癌学会九州支部学術集会
- Place of Presentation
  電気ビル共創館
- Year and Date
  2015-02-27 – 2015-02-28
- Data Source
  KAKENHI-PROJECT-25870518

1. Aragane Naoko (20321846)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. 佐藤明美 (20568357)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
3. KIMURA SHINYA (80359794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 渡邊裕之 (40710786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 木村寛之 (50437240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中島千穂 (40858502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. 末岡尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 20 results

Nakamura Tomomi 中村 朝美

Research Projects

Research Products

Co-Researchers

Cancer comprehensive genomic analysis and establishment of drug efficacy assessment system

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic analysis of characteristics of circulating free DNA on cancer patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Optimization of re-biopsy and liquid biopsy to detect mutations relevant to acquired resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis how circulating plasma DNA release to peripheral blood and that applies to metastatic animal model using human lung cancer cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A non-invasive system for monitoring molecular markers with plasma DNA for tailored medicunePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Anti-cancer effect of afatinib, dual inhibitor of HER2 and EGFR, on novel mutation HER2 E401G in models of patient-derived cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Absence of copy number gain of <i>EGFR</i> : A possible predictive marker of long‐term response to afatinib2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Discontinuation due to immune-related adverse events is a possible predictive factor for immune checkpoint inhibitors in patients with non-small cell lung cancer.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Investigation of appropriate pre-analytical procedure for circulating free DNA from liquid biopsy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current Status and Problems of T790M Detection, a Molecular Biomarker of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors, with Liquid Biopsy and Re-biopsy2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanisms of acquired resistance to afatinib clarified with liquid biopsy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Automated DNA extraction using cellulose magnetic beads can improve EGFR point mutation detection with liquid biopsy by efficiently recovering short and long DNA fragments2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SPARC is a Possible Predictive Marker for Albumin-bound Paclitaxel in Non-small Cell Lung Cancer2016

Author(s)

Journal Title

Data Source

[Journal Article] Usefulness of plasma HGF level for monitoring acquired resistance to EGFR tyrosine kinase inhibitors in non-small cell lung cancer2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Heat Map Analysis, A New Integrated Pathway Scoring System for Cancer Genome Profiling.2023

Author(s)

Nakamura Tomomi 中村朝美