Kai Kentaro 甲斐健太郎

… Alternative Names

KAI Kentaro 甲斐健太郎

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Researcher Number	90457622
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 大分大学, 医学部, 講師 2018 – 2024: 大分大学, 医学部, 助教 2015 – 2017: 大分大学, 医学部, 客員研究員 2013 – 2015: 大分大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 子宮内膜症 / マイクロRNA / 細胞増殖 / エピジェネティクス / COL8A1 / 線維化 / スフィロイド / 細胞増殖能 / 細胞遊走能 / 細胞郵送能 … More / 細胞死 / miRNA / IGFBP1 / Prolactin / プロラクチン / インスリン様成長因子 / 子宮内膜 / プロゲスチン / マイクロアレイ / ネットワーク解析 / ジエノゲスト / 脱落膜化 / ヒストン脱アセチル化酵素阻害薬 / デスレセプター6 / エピジェネティック / アポトーシス / ヒストン脱アセチル化酵素阻害剤 / DR6 / 生殖内分泌学 … More Except Principal Investigator 子宮内膜症 / アポトーシス / 細胞増殖 / ヒストン脱アセチル化酵素 / 細胞周期 / マイクロRNA / 薬物療法 / 瘢痕化 / 腫瘍病理学 / 低侵襲手術 / 腹腔鏡 / 子宮頸癌 / 3次元培養 / ケモカイン / cDNAマイクロアレイ / 線維化 / コラーゲンゲル3次元培養 / 細胞外マトリックス / 収縮能 / 瘢痕形成 / VEGF / microRNA / 病態 / STAT3 / miR-210 / エピジェネティクス / mTOR / Akt / PI3 kinase / Ras homology A / ゲルコントラクションアッセイ / コラーゲンゲル3次元培養法 / statin / mevalonate / Ras homology Less

子宮内膜症の病態形成におけるヒストン脱アセチル化酵素の役割の解明と薬物療法の開発
- Principal Investigator
  
  奈須家栄
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Oita University
子宮内膜症の線維化におけるCOL8A1の役割解明と新規抗線維化療法の開発Principal Investigator
- Principal Investigator
  
  甲斐健太郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Oita University
リアルワールドデータを用いた子宮頸癌診療における低侵襲手術のインパクトの検証
- Principal Investigator
  
  小林栄仁
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Oita University
miR-132をバイオマーカーとした子宮内膜症の早期診断・治療介入の構築Principal Investigator
- Principal Investigator
  
  甲斐健太郎
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Oita University
Pathgenesis of endometriosis-associated fibrosis and development of novel medical treatment
- Principal Investigator
  
  Nasu Kaei
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Oita University
MicroRNA promotes the decidualization of eutopic and ectopic endometrium.Principal Investigator
- Principal Investigator
  
  KAI Kentaro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Oita University
Enhanced miR-210 expression promotes the pathogenesis of endometriosis through activation of signal transducer and activator of transcription 3
- Principal Investigator
  
  Narahara Hisashi
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Oita University
attenuated DR6 expression in endometriosisPrincipal Investigator
- Principal Investigator
  
  KAI Kentaro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Oita University
Pathogenesis and medical treatment of endometriosis-associated fibrosis
- Principal Investigator
  
  Nasu Kaei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Oita University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] I部子宮内膜症　4章治療指針の立て方挙児前の管理　1)痛みのコントロール子宮内膜症・子宮腺筋症　診断アトラス＆新たな治療戦略2021
- Author(s)
  青柳　陽子、甲斐　健太郎、楢原　久司
- Total Pages
  304
- Publisher
  中山書店
- ISBN
  9784521749105
- Data Source
  KAKENHI-PROJECT-20K09602
[Journal Article] Coexistence of Ovarian Endometrioma and Ovarian Pregnancy: A Case Report2023
- Author(s)
  Aoyagi Yoko、Kai Kentaro、Aso Saki、Nishida Masakazu、Kawano Yasushi
- Journal Title
  
  Cureus
  
  Volume: 28
- DOI
  10.7759/cureus.35608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09602, KAKENHI-PROJECT-22K16862
[Journal Article] MicroRNA-210-3p Regulates Endometriotic Lesion Development by Targeting IGFBP3 in Baboons and Women with Endometriosis.2023
- Author(s)
  Kai K, Joshi NR, Burns GW, Hrbek SM, Vegter EL, Ochoa-Bernal MA, Song Y, Moldovan GE, Sempere LF, Miyadahira EH, Serafini PC, Fazleabas AT.
- Journal Title
  
  Reprod Sci.
  
  Volume: 30 Issue: 10 Pages: 2932-2944
- DOI
  10.1007/s43032-023-01253-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09602
[Journal Article] Promising therapeutic targets of endometriosis obtained from microRNA studies2022
- Author(s)
  Kaei Nasu, Yoko Aoyagi, Ruofei Zhu, Mamiko Okamoto, Kentaro Kai, Yasushi Kawano
- Journal Title
  
  Medical Molecular Morphology
  
  Volume: 55 Issue: 2 Pages: 85-90
- DOI
  10.1007/s00795-021-00308-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09622
[Journal Article] Role of repressed microRNAs in endometriosis.2021
- Author(s)
  Kaei Nasu, Yoko Aoyagi, Ruofei Zhu, Mamiko Okamoto, Mitsutake Yano, Kentaro Kai, Yasuhi Kawano.
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 55 Issue: 1 Pages: 1-7
- DOI
  10.1007/s00795-021-00303-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09602, KAKENHI-PROJECT-20K09622, KAKENHI-PROJECT-19K16778
[Journal Article] Endometriosis Epigenetics2018
- Author(s)
  Kentaro Kai, Kaei Nasu, Yoko Aoyagi, Hisashi Narahara
- Journal Title
  
  Curr Womens Health Rev
  
  Volume: 14 Pages: 154-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10679
[Journal Article] Endometriosis Epigenetics2018
- Author(s)
  Kai Kentaro、Nasu Kaei、Aoyagi Yoko、Narahara Hisashi
- Journal Title
  
  Current Women's Health Reviews
  
  Volume: 14 Pages: 154-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20200
[Journal Article] Decidualization Differentially Regulates microRNA Expression in Eutopic and Ectopic Endometrial Stromal Cells.2017
- Author(s)
  Aoyagi Y, Nasu K, Kai K, Hirakawa T, Okamoto M, Kawano Y, Abe W, Tsukamoto Y, Moriyama M, Narahara H.
- Journal Title
  
  Reproductive Sciences
  
  Volume: 24 Issue: 3 Pages: 445-455
- DOI
  10.1177/1933719116657894
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10679, KAKENHI-PROJECT-16K11093, KAKENHI-PROJECT-16K20200
[Journal Article] Endometriosis Epigenetics.2017
- Author(s)
  Kentaro Kai, Kaei Nasu, Yoko Aoyagi, Hisashi Narahara.
- Journal Title
  
  Curr Womens Health Rev.
  
  Volume: 13
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K20200
[Journal Article] 稀少部位子宮内膜症　膀胱・尿管子宮内膜症2017
- Author(s)
  甲斐　健太郎、青柳　陽子、楢原　久司
- Journal Title
  
  産科と婦人科
  
  Volume: 84 Pages: 1347-1354
- Data Source
  KAKENHI-PROJECT-16K20200
[Journal Article] miR-503, a microRNA epigenetically repressed in endometriosis, induces apoptosis and cell-cycle arrest and inhibits cell proliferation, angiogenesis, and contractility of human ovarian endometriotic stromal cells.2016
- Author(s)
  Hirakawa T, Nasu K, Abe W, Aoyagi Y, Okamoto M, Kai K, Takebayashi K, Narahara H.
- Journal Title
  
  Human Reproduction
  
  Volume: 31 Issue: 11 Pages: 2587-2597
- DOI
  10.1093/humrep/dew217
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10679, KAKENHI-PROJECT-16K11093
[Journal Article] miR-503, a microRNA epigenetically repressed in endometriosis, induces apoptosis and cell-cycle arrest and inhibits cell proliferation, angiogenesis, and contractility of human ovarian endometriotic stromal cells.2016
- Author(s)
  Hirakawa T, Nasu K, Abe W, Aoyagi Y, Okamoto M, Kai K, Takebayashi K, Narahara H.
- Journal Title
  
  Hum Reprod.
  
  Volume: 31 Pages: 2587-2597
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K20200
[Journal Article] Enhanced miR-210 expression promotes the pathogenesis of endometriosis through activation of signal transducer and activator of transcription 3.2015
- Author(s)
  Okamoto M, Nasu K, Abe W, Aoyagi Y, Kawano Y, Kai K, Moriyama M et al.
- Journal Title
  
  JOURNAL OF Human Reproduction
  
  Volume: 30 Issue: 3 Pages: 632-641
- DOI
  10.1093/humrep/deu332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460420, KAKENHI-PROJECT-26861335
[Journal Article] Wisteria floribunda agglutinin-binding glycan expression is decreased in endometriomata.2014
- Author(s)
  Hirakawa T, Nasu K, Kai K, Aoyagi Y, Ishii T, Uemura T, Yano M, Narahara H.
- Journal Title
  
  Reprod Biol Endocrinol.
  
  Volume: 12 Issue: 1 Pages: 100-100
- DOI
  10.1186/1477-7827-12-100
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26861335
[Journal Article] Aberrant histone modification in endometriosis.2014
- Author(s)
  Nasu K, Kawano Y, Kai K, Aoyagi Y, Abe W, Okamoto M, Narahara H.
- Journal Title
  
  Front Biosci (Landmark Ed).
  
  Volume: 19 Pages: 1202-1214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861335
[Journal Article] CCAAT/enhancer-binding protein  is epigenetically silenced by histone deacetylation in endometriosis and promotes the pathogenesis of endometriosis.2013
- Author(s)
  Kawano Y, Nasu K, Hijiya N, Tsukamoto Y, Amada K, Abe W, Kai K, Moriyama M, Narahara H
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 98 Issue: 9 Pages: E1474-E1482
- DOI
  10.1210/jc.2013-1608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592407, KAKENHI-PROJECT-25460419, KAKENHI-PROJECT-25462564, KAKENHI-PROJECT-25861500
[Journal Article] Death receptor 6 is epigenetically silenced by histone deacetylation in endometriosis and promotes the pathogenesis of endometriosis.2013
- Author(s)
  Kai K, Nasu K, Kawano Y, Aoyagi Y, Tsukamoto Y, Hijiya N, Abe W, Okamoto M, Moriyama M, Narahara H.
- Journal Title
  
  Am J Reprod Immunol
  
  Volume: 70 Issue: 6 Pages: 485-496
- DOI
  10.1111/aji.12155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592407, KAKENHI-PROJECT-24591952, KAKENHI-PROJECT-25460419, KAKENHI-PROJECT-25462564
[Presentation] HDAC10阻害剤による子宮内膜症の治療効果2024
- Author(s)
  麻生咲季，奈須家栄，青柳陽子，甲斐健太郎，岡本真実子，小林栄仁
- Organizer
  第45回日本エンドメトリオーシス学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09622
[Presentation] miR-132はAkt1を介して子宮内膜症の病態形成に関与する2023
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，河野康志，楢原久司
- Organizer
  令和4年度大分産科婦人科学会・大分県産婦人科医会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09622
[Presentation] SIRT5選択的阻害剤による子宮内膜症の治療効果2023
- Author(s)
  麻生咲季、奈須家栄、甲斐健太郎、岡本真実子、小林英仁
- Organizer
  第68回日本生殖医学会学術講演会・総会
- Data Source
  KAKENHI-PROJECT-20K09602
[Presentation] 選択的SIRT5阻害剤による子宮内膜症の治療効果に関する検討2023
- Author(s)
  麻生咲季、奈須家栄、甲斐健太郎、青柳陽子
- Organizer
  第44回日本エンドメトリオーシス学会
- Data Source
  KAKENHI-PROJECT-20K09602
[Presentation] SIRT5 選択的阻害剤による子宮内膜症の治療効果2023
- Author(s)
  麻生咲季，奈須家栄，青柳陽子，甲斐健太郎，岡本真実子，小林栄仁
- Organizer
  第68回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09622
[Presentation] シンポジウム2「難治性産婦人科疾患における組織形態異常に基づく新規治療戦略への展望」 miR-210は子宮内膜症を促進するのか、抑制するのか？2021
- Author(s)
  甲斐健太郎
- Organizer
  第53回日本臨床分子形態学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09602
[Presentation] miR-132はAkt1を介して子宮内膜症の病態形成に関与する2019
- Author(s)
  青柳陽子，奈須家栄，平川東望子，竹林兼利，朱若菲，甲斐健太郎，楢原久司
- Organizer
  第40回日本エンドメトリオーシス学会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] miR-132 is overexpressed in human ovarian endometriotic stromal cells and promotes the acquisition of endometriotic phenotype2019
- Author(s)
  Yoko Aoyagi, Kaei Nasu, Tomoko Hirakawa, Kanetoshi Takebayashi, Ruofei Zhu, Kentaro Kai, Hisashi Narahara
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症へのAkt経路阻害薬の効果2018
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，平川東望子，竹林兼利，朱若菲，楢原久司
- Organizer
  第63回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症の治療薬としてのAkt 経路阻害薬の効果2018
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，平川東望子，竹林兼利，朱若菲，楢原久司
- Organizer
  第36回日本受精着床学会学術講演会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症におけるmicroRNAの関与　－miR-132はAkt1を介して子宮内膜症の病態形成に関与する－2017
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，平川東望子，竹林兼利，楢原久司
- Organizer
  第38回日本エンドメトリオーシス学会学術講演会
- Place of Presentation
  東京コンベンションホール（東京都中央区）
- Year and Date
  2017-01-21
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] Enhanced miR-132 expression promotes the pathogenesis of endometriosis through the activation of AKT serine/threonine kinase 12017
- Author(s)
  Aoyagi Yoko、Nasu Kaei、Kai Kentaro、Hirakawa Tomoko、Takebayashi Kanetoshi、Narahara Hisashi
- Organizer
  第69回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] Enhanced miR-132 expression promotes the pathogenesis of endometriosis through the activation of AKT serine/threonine kinase 12017
- Author(s)
  Kai Kentaro、Aoyagi Yoko、Nasu Kaei、Hirakawa Tomoko、Takebayashi Kanetoshi、Narahara Hisashi
- Organizer
  日本人類遺伝学会　第62回大会
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] miRNAを介した正常子宮内膜における脱落膜化機構の解明と異所性子宮内膜におけるその異常2017
- Author(s)
  青柳　陽子、奈須　家栄、甲斐　健太郎、平川　東望子、竹林　兼利、楢原　久司
- Organizer
  第22回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] miR-132はAkt1を介して子宮内膜症の病態形成に関与する2017
- Author(s)
  青柳　陽子、奈須　家栄、甲斐　健太郎、平川　東望子、竹林　兼利、楢原　久司
- Organizer
  第62回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] 子宮内膜症におけるmiRNAの関与―miR-132はAkt1を介して子宮内膜症の病態形成に関与する―2017
- Author(s)
  青柳陽子，甲斐健太郎，奈須家栄，平川東望子，竹林兼利，楢原久司
- Organizer
  第38回日本エンドメトリーシス学会
- Place of Presentation
  東京コンベンションホール（東京都中央区）
- Year and Date
  2017-01-21
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] miRNA を介した正常子宮内膜における脱落膜化機構の解明と異所性子宮内膜におけるその異常2017
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，平川東望子，竹林兼利，楢原久司
- Organizer
  第22回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] miR-132はAkt1を介して子宮内膜症の病態形成に関与する2017
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，平川東望子，竹林兼利，楢原久司
- Organizer
  第62回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症におけるmiRNAの関与ーmiR-132はAkt1を介して子宮内膜症の病態形成に関与するー2017
- Author(s)
  青柳　陽子、甲斐　健太郎、奈須　家栄、平川　東望子、竹林　兼利、楢原久司
- Organizer
  第38回日本エンドメトリオーシス学会
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] Enhanced miR-132 expression promotes the pathogenesis of endometriosis through activation of AKT serine/threonine kinase 12017
- Author(s)
  Yoko Aoyagi, Kaei Nasu, Kentaro Kai, Tomoko Hirakawa, Kanetoshi Takebayashi, Hisashi Narahara
- Organizer
  第69回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] miRNAを介した脱落膜化機構の異常による子宮内膜症の発症メカニズム2016
- Author(s)
  青柳陽子，甲斐健太郎，奈須家栄，平川東望子，竹林兼利，楢原久司
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症におけるmiRNAを介した脱落膜化機構の異常2016
- Author(s)
  竹林兼利，甲斐健太郎，奈須家栄，青柳陽子，平川東望子，楢原久司
- Organizer
  第48回日本分子形態学会学術集会
- Place of Presentation
  くまもと県民交流館パレア（熊本県熊本市）
- Year and Date
  2016-09-23
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症におけるmiRNAを介した脱落膜化機構の異常2016
- Author(s)
  青柳陽子，奈須家栄，甲斐健太郎，平川東望子，竹林兼利，楢原久司
- Organizer
  第34回日本受精着床学会学術講演会
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県北佐久郡軽井沢町）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] MicroRNA promotes the decidualization of eutopic and ectopic endometrial stromal cells.2016
- Author(s)
  Kentaro Kai, Yoko Aoyagi, Kaei Nasu, Tomoko Hirakawa, Kanetoshi Takebayashi, Hisashi Narahara.
- Organizer
  The 13th International Congress of Human Genetics
- Place of Presentation
  Kyoto International Conference Center （京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] Decidualization differentially regulates microRNA expression in eutopic and ectopic endometrial stromal cells.2016
- Author(s)
  Yoko Aoyagi, Kaei Nasu, Kentaro Kai, Tomoko Hirakawa, Kanetoshi Takebayashi, Hisashi Narahara.
- Organizer
  5th Asian Conference on Endometriosis (ACE 2016)
- Place of Presentation
  Osaka International Convention Center（大阪府大阪市）
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] miR-503による子宮内膜症間質細胞の細胞外マトリックス収縮能の調節メカニズム2016
- Author(s)
  平川東望子，奈須家栄，青柳陽子，竹林兼利，甲斐健太郎，楢原久司
- Organizer
  第68回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] Decidualization diferrentially regulate microRNA expression in eutopic and ectopic endometrial stromal cells2016
- Author(s)
  Yoko Aoyagi, Kaei Nasu, Kentaro Kai, Tomoko Hirakawa, Kanetoshi Takebayashi, Hisashi Narahara
- Organizer
  5th Asian Conference on Endometriosis (ACE2016)
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2016-09-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] Decidualization differentially regulates microRNA expression in eutopic and ectopic endometrial stromal cells.2016
- Author(s)
  Yoko Aoyagi, Kaei Nasu, Kentaro Kai, Tomoko Hirakawa, Kanetoshi Takebayashi, and Hisashi Narahara
- Organizer
  第68回日本参加婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Year and Date
  2016-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] miR-503による卵巣子宮内膜症間質細胞の細胞外マトリックス収縮能の調節メカニズム2016
- Author(s)
  平川東望子，奈須家栄，青柳陽子，竹林兼利，甲斐健太郎，楢原久司
- Organizer
  第37回日本エンドメトリオーシス学会学術講演会
- Place of Presentation
  熊本市・ホテル日航熊本
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] miR-503による子宮内膜症間質細胞の細胞外マトリックス収縮能の調節メカニズム2016
- Author(s)
  平川東望子，奈須家栄，青柳陽子，竹林兼利，甲斐健太郎，楢原久司
- Organizer
  日本産科婦人科学会第68回学術講演会
- Place of Presentation
  東京都・東京国際フォーラム
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症におけるmiRNAを介した脱落膜化機構の異常2016
- Author(s)
  甲斐健太郎
- Organizer
  神澤医学研究振興財団　第18回講演会
- Place of Presentation
  ホテルオークラ東京（東京都港区）
- Invited
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] Decidualization differentially regulates microRNA expression in eutopic and ectopic endometrial stromal cells.2016
- Author(s)
  Yoko Aoyagi, Kaei Nasu, Kentaro Kai, Tomoko Hirakawa, Kanetoshi Takebayashi, Hisashi Narahara.
- Organizer
  第34回日本授精着床学学術講演会
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県北佐久郡軽井沢町）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-16K20200
[Presentation] miRNAを介した脱落膜化機構の異常による子宮内膜症の発症メカニズム2016
- Author(s)
  青柳陽子，甲斐健太郎，奈須家栄，平川東望子，竹林兼利，楢原久司
- Organizer
  日本産科婦人科学会第68回学術講演会
- Place of Presentation
  東京都・東京国際フォーラム
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症の病態形成におけるmiR-100の発現亢進の意義2016
- Author(s)
  竹林兼利，奈須家栄，平川東望子，甲斐健太郎，青柳陽子，楢原久司
- Organizer
  第34回日本受精着床学会学術講演会
- Place of Presentation
  軽井沢プリンスホテルウエスト（長野県北佐久郡軽井沢町）
- Year and Date
  2016-09-15
- Data Source
  KAKENHI-PROJECT-15K10679
[Presentation] 子宮内膜症におけるmiRNAを介した脱落膜化機構の異常2016
- Author(s)
  青柳陽子，甲斐健太郎，奈須家栄，平川東望子，竹林兼利，楢原久司
- Organizer
  第37回日本エンドメトリオーシス学会学術講演会
- Place of Presentation
  熊本市・ホテル日航熊本
- Year and Date
  2016-01-23
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症の病態形成におけるmiR-210の発現増加の意義2015
- Author(s)
  岡本真実子，奈須家栄，甲斐健太郎，平川東望子，青柳陽子，楢原久司
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜市・パシフィコ横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] Wisteria floribunda agglutinin-binding glycan expression is decreased in endometriosis2015
- Author(s)
  Kentaro Kai, Kaei Nasu, Tomoko Hirakawa, Yoko Aoyagi, Terukazu Ishii, Tetsuya Uemura, Mitsutake Yano, Hisashi Narahara
- Organizer
  Society for Reproductive Investigation 62nd Annual Scientific Meeting
- Place of Presentation
  Hilton San Francisco Union Square, San Francisco, CA, USA
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PROJECT-26861335
[Presentation] 子宮内膜症におけるmiR-210の発現低下は病態形成に関与する2015
- Author(s)
  奈須家栄，岡本真実子，青柳陽子，甲斐健太郎，平川東望子，竹林兼利，河野康志，楢原久司
- Organizer
  第33回日本受精着床学会総会・学術講演会
- Place of Presentation
  東京都江東区・TFTホール
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 卵巣子宮内膜症が卵巣反応性および卵発育能に及ぼす影響2015
- Author(s)
  原田枝美，河野康志，山下由貴，甲斐由布子，奈須家栄，楢原久司
- Organizer
  第33回日本受精着床学会総会・学術講演会
- Place of Presentation
  東京都江東区・TFTホール
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] miR-210を介した子宮内膜間質細胞の脱落膜化とその意義2015
- Author(s)
  甲斐健太郎，奈須家栄, 青柳陽子, 岡本真実子, 平川東望子, 楢原久司
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  東京都千代田区・ホテルニューオータニ東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] Death Receptor 6 is Epigenetically Silenced by Histone Deacetylation in Endometriosis and Promotes the Pathogenesis of Endometriosis2015
- Author(s)
  Kentaro Kai, Kaei Nasu, Yoko Aoyagi, Mamiko Okamoto, Hirakawa Tomoko, Hisashi Narahara
- Organizer
  IFFS/JSRM International Meeting 2015 in Yokohama
- Place of Presentation
  Pacifico Yokohama（神奈川県横浜市）
- Year and Date
  2015-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861335
[Presentation] 子宮内膜症間質細胞におけるSTAT3 inhibitorの効果2015
- Author(s)
  岡本真実子，奈須家栄，青柳陽子，甲斐健太郎，平川東望子，楢原久司
- Organizer
  第30回日本生殖免疫学会学術集会
- Place of Presentation
  熊本市・熊本県民交流館パレア
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症ではmiR-503発現低下によりRho-ROCK pathway活性化を介して収縮能が亢進する2015
- Author(s)
  平川東望子，奈須家栄，青柳陽子，竹林兼利，岡本真実子，甲斐健太郎，楢原久司
- Organizer
  第47回日本臨床分子形態学会学術集会
- Place of Presentation
  長崎市・長崎大学医学部良順会館、ポンペ会館
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] miR-503は卵巣子宮内膜症性嚢胞間質細胞のアポトーシスを誘導し細胞周期を停止させる2015
- Author(s)
  平川東望子，奈須家栄，甲斐健太郎，青柳陽子，岡本真実子，河野康志，楢原久司
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜市・パシフィコ横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症でmiR-503の発現が低下している2015
- Author(s)
  平川東望子，奈須家栄，青柳陽子，岡本真実子，甲斐健太郎，楢原久司
- Organizer
  第57回日本婦人科腫瘍学会
- Place of Presentation
  盛岡市・イーナいわて県民情報交流センター・マリオス盛岡地域交流センター
- Year and Date
  2015-08-07
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症におけるアポトーシス受容体DR6の発現低下と病態形成への関与2014
- Author(s)
  甲斐健太郎，奈須家栄，川野由紀枝，阿部若菜，岡本真実子，楢原久司
- Organizer
  第35回日本エンドメトリオーシス学会
- Place of Presentation
  鹿児島市・城山観光ホテル
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] レクチンマイクロアレイを用いた子宮内膜症における糖鎖プロファイリングの解析2014
- Author(s)
  平川東望子，奈須家栄，甲斐健太郎，青柳陽子，植村徹也，川野由紀枝，石井照和，楢原久司
- Organizer
  第35回日本エンドメトリオーシス学会
- Place of Presentation
  鹿児島市・城山観光ホテル
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症病態形成におけるがん抑制遺伝子C/EBPαの関与についての検討2013
- Author(s)
  川野由紀枝，奈須家栄，阿部若菜，甲斐健太郎，岡本真実子，河野康志，楢原久司
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  札幌市・ロイトン札幌，ホテルさっぽろ芸文館，札幌プリンスホテル，札幌市教育文化会館
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症におけるエピジェネティクス異常2013
- Author(s)
  川野由紀枝，奈須家栄，阿部若菜，甲斐健太郎，岡本真実子，河野康志，楢原久司
- Organizer
  第45回日本臨床分子形態学会学術講演会
- Place of Presentation
  福岡市・アクロス福岡
- Invited
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] 子宮内膜症間質細胞におけるmiR-196bの発現低下は子宮内膜症の病態形成に関与する2013
- Author(s)
  奈須家栄，阿部若菜，川野由紀枝，甲斐健太郎，岡本真実子，河野康志，楢原久司
- Organizer
  第65回日本産科婦人科学会学術講演会
- Place of Presentation
  札幌市・ロイトン札幌，ホテルさっぽろ芸文館，札幌プリンスホテル，札幌市教育文化会館
- Data Source
  KAKENHI-PROJECT-25462564
[Presentation] DR6 is epigenetically involved in the pathogenesis of endometriosis by creating the proliferative and anti-apoptotic characteristics
- Author(s)
  Kentaro Kai, Kaei Nasu, Yoko Aoyagi, Yoshiyuki Tsukamoto, Naoki Hijiya, Mamiko Okamoto, Masatsugu Moriyama, Hisashi Narahara
- Organizer
  第29回日本生殖免疫学会
- Place of Presentation
  文京区・伊藤国際学術研究センター
- Year and Date
  2014-12-12 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-26861335
[Presentation] Death receptor 6 is epigenetically silenced by histone deacetylation in endometriosis and promotes the pathogenesis of endometriosis
- Author(s)
  Kentaro Kai, Kaei Nasu, Yukie Kawano, Wakana Abe, Mamiko Okamoto, Hisashi Narahara
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  千代田区・東京国際フォーラム
- Year and Date
  2014-04-18 – 2015-04-20
- Data Source
  KAKENHI-PROJECT-26861335
[Presentation] Death receptor 6 is epigenetically silenced by histone deacetylation in endometriosis
- Author(s)
  Kentaro Kai, Kaei Nasu, Yoko Aoyagi, Yoshiyuki Tsukamoto, Naoki Hijiya, Mamiko Okamoto, Masatsugu Moriyama, Hisashi Narahara
- Organizer
  第59回日本人類遺伝学会
- Place of Presentation
  江戸川区・タワーホール船堀
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26861335
[Presentation] Death receptor 6 is epigenetically silenced by histone deacetylation in Endometriosis and Promotes the Pathogenesis of Endometriosis
- Author(s)
  Kentaro Kai, Kaei Nasu, Yoko Aoyagi, Yoshiyuki Tsukamoto, Naoki Hijiya, Mamiko Okamoto, Masatsugu Moriyama, Hisashi Narahara
- Organizer
  3rd Asian Conference of Endometriosis
- Place of Presentation
  Songeui Medical Campus, The Catholic University of Korea, Seoul, Korea
- Year and Date
  2014-10-24 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-26861335
[Presentation] 子宮内膜症におけるDNAメチル化の異常
- Author(s)
  川野由紀枝，奈須家栄，阿部若菜，甲斐健太郎，河野康志，楢原久司
- Organizer
  第70回九州・沖縄生殖医学会
- Place of Presentation
  福岡市・エルガーラホール
- Data Source
  KAKENHI-PROJECT-25462564

1. Nasu Kaei (30274757)

# of Collaborated Projects: 6 results

# of Collaborated Products: 44 results
2. KAWANO YASUSHI (40274758)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. NARAHARA HISASHI (60211447)

# of Collaborated Projects: 2 results

# of Collaborated Products: 37 results
4. 平川東望子 (20516132)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
5. 西田正和 (90404384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 小林栄仁 (50614773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ABE WAKANA (30457618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. KAWANO YUKIE (60516128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. YUGE AKITOSHI (90452911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 青柳陽子 (00883828)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 麻生咲季 (60962074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 上田豊 (10346215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 八木麻未 (30793450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中谷英仁 (80627670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 守山正胤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kai Kentaro 甲斐 健太郎

KAI Kentaro 甲斐 健太郎

Research Projects

Research Products

Co-Researchers

子宮内膜症の病態形成におけるヒストン脱アセチル化酵素の役割の解明と薬物療法の開発

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子宮内膜症の線維化におけるCOL8A1の役割解明と新規抗線維化療法の開発Principal Investigator

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リアルワールドデータを用いた子宮頸癌診療における低侵襲手術のインパクトの検証

Principal Investigator

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miR-132をバイオマーカーとした子宮内膜症の早期診断・治療介入の構築Principal Investigator

Principal Investigator

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Pathgenesis of endometriosis-associated fibrosis and development of novel medical treatment

Principal Investigator

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MicroRNA promotes the decidualization of eutopic and ectopic endometrium.Principal Investigator

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Enhanced miR-210 expression promotes the pathogenesis of endometriosis through activation of signal transducer and activator of transcription 3

Principal Investigator

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attenuated DR6 expression in endometriosisPrincipal Investigator

Principal Investigator

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Pathogenesis and medical treatment of endometriosis-associated fibrosis

Principal Investigator

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[Book] I部子宮内膜症 4章治療指針の立て方 挙児前の管理 1)痛みのコントロール 子宮内膜症・子宮腺筋症 診断アトラス＆新たな治療戦略2021

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[Journal Article] Coexistence of Ovarian Endometrioma and Ovarian Pregnancy: A Case Report2023

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[Journal Article] MicroRNA-210-3p Regulates Endometriotic Lesion Development by Targeting IGFBP3 in Baboons and Women with Endometriosis.2023

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[Journal Article] Promising therapeutic targets of endometriosis obtained from microRNA studies2022

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Kai Kentaro 甲斐健太郎

KAI Kentaro 甲斐健太郎

[Book] I部子宮内膜症　4章治療指針の立て方挙児前の管理　1)痛みのコントロール子宮内膜症・子宮腺筋症　診断アトラス＆新たな治療戦略2021

[Journal Article] 稀少部位子宮内膜症　膀胱・尿管子宮内膜症2017

[Journal Article] CCAAT/enhancer-binding protein  is epigenetically silenced by histone deacetylation in endometriosis and promotes the pathogenesis of endometriosis.2013