Hontsu Shigeto 本津茂人

… Alternative Names

Shigeto Hontsu 本津茂人

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Researcher Number	90458034
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2025: 奈良県立医科大学, 医学部, 准教授 2017 – 2022: 奈良県立医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine Except Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 制御性Ｔ細胞 / 合併肺癌 / 特発性肺線維症 / 特発性間質性肺炎合併肺癌 / 肺癌 / 肺線維症 / 肺線維症合併肺癌 / 制御性T細胞 Except Principal Investigator 線維芽細胞 / ANGPTL4 … More / 肺線維症 / 病原性線維芽細胞 / 線維化 / シングルセル遺伝子発現解析 / TGF-beta / 増悪化因子 / 筋線維芽細胞 / 特発性肺線維症 Less

特発性肺線維症合併肺癌における腫瘍と線維化を同時制御する新たな治療戦略の開発Principal Investigator
- Principal Investigator
  
  本津茂人
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nara Medical University
肺線維症における病原性線維芽細胞の持続活性化制御による新規治療戦略の確立
- Principal Investigator
  
  北畠正大
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nara Medical University
Elucidation of pathology of pulmonary fibrosis by a lipid metabolism-related molecule ANGPTL4.
- Principal Investigator
  
  Maahiro Kitabatake
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nara Medical University
Search for new therapeutic strategies targeting regulatory T cells for lung cancer with pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  Shigeto Hontsu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nara Medical University

All 2023 2022 2021 2020 2019 2017

All Journal Article Presentation

[Journal Article] Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development2023
- Author(s)
  Shoichiro Saito, Masahiro Kitabatake, Noriko Ouji-Sageshima, Tatsuro Ogawa, Akihisa Oda, Tomoko Nishimura, Tatsuki Nishioka, Satoki Fushimi, Atsushi Hara, Shigeyuki Shichino, Makiko Kumamoto, Shigeto Hontsu, Takeshi Kawaguchi, Satoshi Ueha, Noriyoshi Sawabata, Shigeo Muro, Kouji Matsushima, Toshihiro Ito
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: - Issue: 3 Pages: 328-339
- DOI
  10.1165/rcmb.2022-0304oc
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08661, KAKENHI-PROJECT-23K07632, KAKENHI-PROJECT-21K07825, KAKENHI-PROJECT-21K08162, KAKENHI-PLANNED-22H05064
[Journal Article] TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.2022
- Author(s)
  Shichino S, Ueha S, Hashimoto S, Ogawa T, Aoki H, Wu B, Chen CY, Kitabatake M, Ouji-Sageshima N, Sawabata N, Kawaguchi T, Okayama T, Sugihara E, Hontsu S, Ito T, Iwata Y, Wada T, Ikeo K, Sato TA, Matsushima K.
- Journal Title
  
  Commun Biol
  
  Volume: 5 Issue: 1 Pages: 602-602
- DOI
  10.1038/s42003-022-03536-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08162, KAKENHI-PROJECT-21K08224, KAKENHI-PROJECT-22K07179, KAKENHI-PROJECT-20H03474, KAKENHI-WRAPUP-22H04906
[Journal Article] Remarkable response of non‐small cell lung cancer to nintedanib treatment in a patient with idiopathic pulmonary fibrosis2021
- Author(s)
  Kai Yoshiro、Matsuda Masayuki、Fukuoka Atsuhiko、Hontsu Shigeto、Yamauchi Motoo、Yoshikawa Masanori、Muro Shigeo
- Journal Title
  
  Thoracic Cancer
  
  Volume: 12 Issue: 9 Pages: 1457-1460
- DOI
  10.1111/1759-7714.13935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09315, KAKENHI-PROJECT-17K09663
[Journal Article] Human Adipose-Derived Mesenchymal Stem Cells Ameliorate Elastase-Induced Emphysema in Mice by Mesenchymal-Epithelial Transition.2021
- Author(s)
  Fujioka N, Kitabatake M, Ouji-Sageshima N, Ibaraki T, Kumamoto M, Fujita Y, Hontsu S, Yamauchi M, Yoshikawa M, Muro S, Ito T.
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 8 Pages: 2783-2793
- DOI
  10.2147/copd.s324952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17642, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
[Journal Article] Linac-Based Fractionated Stereotactic Radiotherapy With a Micro-Multileaf Collimator for Brainstem Metastasis2019
- Author(s)
  T Sugimoto , R Matsuda , T Tamamoto , S Hontsu , K Yamaki , S Miura , Y-S Park , H Nakase , M Hasegawa
- Journal Title
  
  World Neurosurg
  
  Volume: 132 Pages: 680-686
- DOI
  10.1016/j.wneu.2019.08.049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09663, KAKENHI-PROJECT-18H02915
[Presentation] 肺線維症の病態制御因子としてのAngiopoietin-like 4の役割2023
- Author(s)
  齊藤正一郎、北畠正大、王寺典子、古川龍太郎、西村知子、本津茂人、川口剛史、澤端章好、室繁郎、伊藤利洋
- Organizer
  第62日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K08162
[Presentation] Angiopoietin-like 4は肺線維症の病態を制御する―肺線維症患者肺検体とマウスモデルでの解析2022
- Author(s)
  齊藤正一郎、北畠正大、王寺典子、古川龍太郎、西村知子、本津茂人、川口剛史、澤端章好、室繁郎、伊藤利洋
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K08162
[Presentation] 免疫チェックポイント阻害剤投与中に免疫関連有害事象としての心筋炎が疑われた4例2020
- Author(s)
  大田正秀、長　敬翁、田﨑正人、太田浩世、藤田幸男、山本佳史、本津茂人、山内基雄、吉川雅則、室　繁郎、中川　仁、大林千穂
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 当科におけるデュルバルマブ維持療法の臨床経験2020
- Author(s)
  本津茂人、田﨑正人、太田浩世、熊本牧子、長　敬翁、藤田幸男、山本佳史、山内基雄、吉川雅則、室繁郎
- Organizer
  第60回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 肺線維症の病因・病態　特発性肺線維症におけるAngiopoietin-like 4の役割　ヒト肺検体とマウスモデルでの検討2020
- Author(s)
  斎藤正一郎、北畠正大、王寺典子、熊本牧子、西村知子、本津茂人、安川元章、川口剛史、澤端章好、谷口繁樹、室繁郎、伊藤利洋
- Organizer
  第60回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 細胞診塗抹標本より回収した肺腺癌細胞から遺伝子変異検出をし得た一例2020
- Author(s)
  藤井智美、内山智子、武田麻衣子、鈴木久恵、龍見重信、西川武、大田正秀、本津茂人、大林千穂
- Organizer
  第61回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 特発性肺線維症に対する脂肪由来間葉系幹細胞療法への試み2019
- Author(s)
  伊藤利洋　檜山愛子　熊本牧子　北畠正大　王寺典子　本津茂人　安川元章　川口剛史　澤端章好　谷口繁樹　室　繁郎
- Organizer
  第59回　日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 当院におけるデュルバルマブ維持療法の治療経験2019
- Author(s)
  本津茂人　田崎正人　太田浩世　熊本牧子　長　敬翁　藤田　幸男　山本佳史　山内基雄　吉川雅則　室　繁郎
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 胸部放射線治療後の免疫チェックポイント阻害剤の安全性、有効性の検討2019
- Author(s)
  本津茂人　田崎正人　太田浩世　熊本牧子　長　敬翁　鵜山広樹　藤田幸男　山本佳史　友田恒一　山内基雄　吉川雅則　室　繁郎
- Organizer
  第59回　日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] 当院におけるEGFR uncommon mutation陽性肺癌の検討2019
- Author(s)
  田﨑正人　本津茂人　山本佳史　藤田幸男　熊本牧子　太田浩世　長　敬翁　山内基雄　吉川雅則　室　繁郎
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] The safety assessment of crizotinib and alectinib from real world date of 840 ALK-inhibitor naive patients with NSCLC harboring ALK-rearrangement (WJOG9516L)2019
- Author(s)
  K. Kunimasa, K. Ito, T. Yamanaka, D. Fujimoto, M. Mori, K. Maeno, K. Tomomatsu, A. Tamura, H. Tanaka, S. Watanabe, S. Teraoka, O. Hataji, K. Suzuki, S. Hontsu, S. Hara15, A. Bessho, A. Kubo, M. Okuno, K. Nakagawa, N. Yamamoto
- Organizer
  ESMO 2019 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09663
[Presentation] T790M変異の検索目的で再生検を施行したEGFR遺伝子変異陽性肺腺癌の検討2017
- Author(s)
  本津茂人、田崎正人、藤田幸男、長　敬翁、熊本牧子、太田浩世、山本佳史、山内基雄、友田恒一、吉川雅則、木村　弘
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09663

1. Maahiro Kitabatake (60457588)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. 上羽悟史 (00447385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 伊藤利洋 (00595712)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 小田朗永 (80547703)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MURO Shigeo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. YAMAUCHI Motoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 熊本牧子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 吉川雅則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 藤田幸男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hontsu Shigeto 本津 茂人

Shigeto Hontsu 本津 茂人

Research Projects

Research Products

Co-Researchers

特発性肺線維症合併肺癌における腫瘍と線維化を同時制御する新たな治療戦略の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肺線維症における病原性線維芽細胞の持続活性化制御による新規治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathology of pulmonary fibrosis by a lipid metabolism-related molecule ANGPTL4.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for new therapeutic strategies targeting regulatory T cells for lung cancer with pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Angiopoietin-like 4 is a critical regulator of fibroblasts during pulmonary fibrosis development2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TAS-Seq is a robust and sensitive amplification method for bead-based scRNA-seq.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Remarkable response of non‐small cell lung cancer to nintedanib treatment in a patient with idiopathic pulmonary fibrosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human Adipose-Derived Mesenchymal Stem Cells Ameliorate Elastase-Induced Emphysema in Mice by Mesenchymal-Epithelial Transition.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Linac-Based Fractionated Stereotactic Radiotherapy With a Micro-Multileaf Collimator for Brainstem Metastasis2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 肺線維症の病態制御因子としてのAngiopoietin-like 4の役割2023

Author(s)

Organizer

Data Source

[Presentation] Angiopoietin-like 4は肺線維症の病態を制御する―肺線維症患者肺検体とマウスモデルでの解析2022

Author(s)

Organizer

Data Source

[Presentation] 免疫チェックポイント阻害剤投与中に免疫関連有害事象としての心筋炎が疑われた4例2020

Author(s)

Organizer

Data Source

[Presentation] 当科におけるデュルバルマブ維持療法の臨床経験2020

Author(s)

Organizer

Data Source

[Presentation] 肺線維症の病因・病態 特発性肺線維症におけるAngiopoietin-like 4の役割 ヒト肺検体とマウスモデルでの検討2020

Author(s)

Organizer

Data Source

[Presentation] 細胞診塗抹標本より回収した肺腺癌細胞から遺伝子変異検出をし得た一例2020

Author(s)

Organizer

Data Source

[Presentation] 特発性肺線維症に対する脂肪由来間葉系幹細胞療法への試み2019

Author(s)

Hontsu Shigeto 本津茂人

Shigeto Hontsu 本津茂人

[Presentation] 肺線維症の病因・病態　特発性肺線維症におけるAngiopoietin-like 4の役割　ヒト肺検体とマウスモデルでの検討2020