Ohtomo Takayuki 大友隆之

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OHTOMO Takayuki 大友隆之

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Researcher Number	90463108
Other IDs
Affiliation (Current)	2024: 東京薬科大学, 薬学部, 講師 2024: 独立行政法人国立病院機構(相模原病院臨床研究センター), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 東京薬科大学, 薬学部, 講師 2018 – 2020: 東京薬科大学, 薬学部, 助教 2012 – 2013: 東京薬科大学, 薬学部, 助教 2011: 独立行政法人国立病院機構相模原病院, 臨床研究センター, 特別研究員 2010 – 2011: 独立行政法人国立病院機構(相模原病院臨床研究センター), 先端技術開発研究部, 研究員 2009: 独立行政法人国立病院機構(相模原病院臨床研究センター), 先端技術開発部, 特別研究員
Review Section/Research Field	Principal Investigator Biological pharmacy Except Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Respiratory organ internal medicine
Keywords	Principal Investigator T細胞 / アレルギー / 気管支喘息 Except Principal Investigator T細胞 / 気管支喘息 / 遅発型喘息反応 / メディエータ / 喘息 / 炎症 / ステロイド抵抗性 … More / アレルギー / 気管支平滑筋 / IL-5 / 細胞性免疫 / アレルゲン / 閉塞性肺疾患 Less

T細胞依存性遅発型喘息反応メディエータの解明
- Principal Investigator
  
  森晶夫
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
Investigation on steroid resistant airway inflammation
- Principal Investigator
  
  MORI AKIO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital
Development of new refractory asthma treatments of targeting OX40 ligand.Principal Investigator
- Principal Investigator
  
  OHTOMO TAKAYUKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Clarification of causal antigens of bronchial asthma in terms of cellular immune responses and mediators of bronchoconstriction
- Principal Investigator
  
  MORI Akio
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital

All 2023 2022 2021 2020 2019 2018 2013 2012 2010 2009

All Journal Article Presentation

[Journal Article] 重症喘息のステロイド抵抗性とその制御2022
- Author(s)
  森　晶夫、神山　智、大友　暁美、山口　美也子、組谷　智恵美、岩本　圭右、矢野　光一、藤田　教寛、岩田　真紀、永山　貴紗子、劉　楷、中村　祐人、濱田　祐斗、渡井　健太郎、上出　庸介、福冨　友馬、関谷　潔史、松本　幸一郎、谷本　安、小林　信之、大友　隆之、神沼　修
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 157 Pages: 293-298
- Data Source
  KAKENHI-PROJECT-21K08486
[Journal Article] Murine T cell-derived contractile activity for human bronchial smooth muscle cells2012
- Author(s)
  Abe, A., Koyama, S., Ohtomo, T., Kitamura, N., Kaminuma, O., and Mori, A.
- Journal Title
  
  Int. Arch. Allergy Immunol
  
  Volume: 158 Issue: Suppl. 1 Pages: 7-10
- DOI
  10.1159/000337743
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590978, KAKENHI-PROJECT-22790773
[Journal Article] Eosinophils are required for the induction of bronchial hyperresponsiveness in a Th transfer model of Balb/c background2010
- Author(s)
  Ohtomo, T., Kaminuma, O., Yamada, J., Kitamura, N., Abe, A., Kobayashi, N., Suko, M., and Mori, A.
- Journal Title
  
  Int. Arch. Allergy Immunol
  
  Volume: 152 Issue: Suppl. 1 Pages: 79-82
- DOI
  10.1159/000312130
- Data Source
  KAKENHI-PROJECT-21590978
[Journal Article] Murine Th clones confer late asthmatic response upon antigen challenge2009
- Author(s)
  Ohtomo, T., et al.
- Journal Title
  
  Int.Arch.Allergy Immunol. 149
  
  Pages: 2-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590978
[Presentation] Biological and biochemical analysis of T cell derived bronchoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasaki, Y., Iwata, M., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  European Respiratory Society 2023 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Pharmacological characterization of T cell-induced bronchoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasai, Y., Iwata, M., Nakamura, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  World Allergy Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Cellular Analysis of T cell-dependent steroid-resistant asthma2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasaki, Y., Nakamura, Y., Kamide, Y., Sekiya, K., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  Asia Pacific Association of Allergy, Asthma and Clinical Immunology International Conference 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Cellular and molecular analysis of T cell-dependent steroid-resistant asthma model2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasaki, Y., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  Asia Pacific Society of Respirology 2023 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Biochemical analysis of T cell dependent bronchoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Tawasaki, Y., Iwata, M., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O., and Mori, A.
- Organizer
  American Academy of Allergy Asthma & Immunology Annual Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Biochemical characterization of T cell derived bronvhoconstriction2023
- Author(s)
  Kouyama, S., Ohtomo-Abe, A., Kawasai, Y., Iwata, M., Nakamura, Y., Hamada, Y., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O. and Mori, A.
- Organizer
  European Academy of Allergy and Clinical Immunology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] T cell-dependent steroid-resistant asthma is mediated by tyrosine kinases of costimulatory signal2022
- Author(s)
  Mori, A., Kouyama, S., Ohtomo-Abe, A., Iwamoto, K., Yano, K., Fujita, N., Iwata, M., Nagayama, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology Hybrid Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Control of T cell-dependent steroid-resistant asthma model by several kinase inhibitors2022
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Ohtomo-Abe, A., Iwamoto, K., Yano, K., Fujita, N., Iwata, M., Nagayama K., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., Kaminuma, O.
- Organizer
  European Respiratory Society International Congress 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] 重症喘息のステロイド抵抗性とその制御2022
- Author(s)
  森　晶夫、神山　智、大友暁美、山口美也子、組谷千恵美、岩本圭右、矢野光一、藤田教寛、岩田真紀、永山貴紗子、劉　楷、中村祐人、濱田祐斗、渡井健太郎、上出庸介、福冨友馬、関谷潔史、松元幸一郎、谷口　安、小林信之、大友隆之、神沼　修
- Organizer
  第95回日本薬理学会年会　シンポジウム27　難治性ぜんそく治療への新たな挑戦
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Pharmacological characterization of T cell-induced bronchoconstriction in vivo and in vitro2021
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, Y., Kumitani, C., Ohtomo-Abe, A., Kawasaki, Y., Iwamoto, K., Yano, K., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Ohtomo, T., and Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology Hybrid Congress 2021　(Madrid-Krakow, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Possible mechanisms of T cell-induced bronchoconstriction2021
- Author(s)
  Mori, A., Kouyama, S., Ohtomo-Abe, A., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Ohtomo, T., Kaminuma, O.
- Organizer
  Asia Pacific Association of Allergy, Asthma and Clinical Immunology International Conference 2021 (Taipei, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Molecular characterization of bronchoconstriction induced by activated T cells2021
- Author(s)
  Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Kawasaki, Y., Iwamoto, K., Yano, K., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Ohtomo, T., Kaminuma, O, and Mori, A.
- Organizer
  European Respiratory Society 2021 International Congress (London, on line)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08486
[Presentation] Pharmacological analysis of T cell-dependent steroid-resistant asthma2020
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Yano, K., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Taniguchi, Ohtomo, T., and Kaminuma, O.
- Organizer
  European Respiratory Society 2020 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Pharmacological analysis of helper T cell-dependent, steroid-resistant asthma2020
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Synergistic suppression of T cell-induced eosinophilia by glucocorticoid and CTLA4-Ig2019
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  American Academy of Allergy Asthma & Immunology Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Control of steroid resistance by blocking costimulatory signal2019
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  WAO International Scientific Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] CD28 signal blockade as a treatment for steroid resistant asthma2019
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  17th International Congress of Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] T cell-induced bronchoconstriction in mice2018
- Author(s)
  Kouyama, S., Ohtomo, T., Kaminuma, O., and Mori, A.
- Organizer
  American College of Allergy and Immunology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Mechanisms of nonatopic, T cell-induced bronchoconstriction.2018
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Ohtomo-Abe, A., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  WAO International Scientific Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] Pharmacological characterization of T cell-induced broncho-constriction in vitro and in vivo.2018
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Kumitani, C., Fujita, N., Iwata, M., Nagayama, K., Ryu, K., Nakamura, Y., Tomita, Y., Hamada, Y., Hayashi, H., Watai, K., Kamide, Y., Sekiya, K., Fukutomi, Y., T., Taniguchi, M., Ohtomo, T., Kaminuma, O.
- Organizer
  European Respiratory Society 2018 International Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08422
[Presentation] 非アトピー型喘息のマウスモデル作成と解析2013
- Author(s)
  神山智、大友暁美、大友隆之、山口美也子,飯島葉、森晶夫
- Organizer
  第44回日本職業・環境アレルギー学会総会・学術大会
- Place of Presentation
  相模原市
- Data Source
  KAKENHI-PROJECT-24790093
[Presentation] Adoptive transfer of Th clones confer late-phase asthmatic response in mice.2013
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Iijima, Y., Itoh, J., Saito, N., Minami, T ., Watarai, K., Mitsui, C., Oshikata, C., Tanimoto, H., Fukutomi, Y., Sekiya, K. , Tsuburai, T., Taniguchi, M., Maeda, Y., Ohtomo, M., Hasegawa, M., Akiyama, K., Ohtomo, T., and Kaminuma, O.
- Organizer
  European Academy of Allergy and Clinical Immunology-World Allergy Organization World Allergy & Asthma Congress 2013
- Place of Presentation
  Milan, Italy
- Data Source
  KAKENHI-PROJECT-24790093
[Presentation] Adoptive transfer of Th clones confer late-phase asthmatic response in mice, European Academy of Allergy and Clinical Immunology-World Allergy2013
- Author(s)
  Mori, A., Kouyama, S., Yamaguchi, M., Iijima, Y., Itoh, J., Saito, N., Minami, T., Watarai, K., Mitsui, C., Oshikata, C., Tanimoto, H., Fukutomi, Y., Sekiya, K., Tsuburai, T., Taniguchi, M., Maeda, Y., Ohtomo, M., Hasegawa, M., Akiyama, K., Ohtomo, T., Kaminuma, O
- Organizer
  Organization World Allergy &Asthma Congress
- Place of Presentation
  Italy
- Data Source
  KAKENHI-PROJECT-24790093

1. MORI Akio (80251247)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
2. 神山智 (20626783)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
3. 神沼修 (80342921)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results

Ohtomo Takayuki 大友 隆之

OHTOMO Takayuki 大友 隆之

Research Projects

Research Products

Co-Researchers

T細胞依存性遅発型喘息反応メディエータの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation on steroid resistant airway inflammation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new refractory asthma treatments of targeting OX40 ligand.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clarification of causal antigens of bronchial asthma in terms of cellular immune responses and mediators of bronchoconstriction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 重症喘息のステロイド抵抗性とその制御2022

Author(s)

Journal Title

Data Source

[Journal Article] Murine T cell-derived contractile activity for human bronchial smooth muscle cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Eosinophils are required for the induction of bronchial hyperresponsiveness in a Th transfer model of Balb/c background2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Murine Th clones confer late asthmatic response upon antigen challenge2009

Author(s)

Journal Title

Data Source

[Presentation] Biological and biochemical analysis of T cell derived bronchoconstriction2023

Author(s)

Organizer

Data Source

[Presentation] Pharmacological characterization of T cell-induced bronchoconstriction2023

Author(s)

Organizer

Data Source

[Presentation] Cellular Analysis of T cell-dependent steroid-resistant asthma2023

Author(s)

Organizer

Data Source

[Presentation] Cellular and molecular analysis of T cell-dependent steroid-resistant asthma model2023

Author(s)

Organizer

Data Source

[Presentation] Biochemical analysis of T cell dependent bronchoconstriction2023

Author(s)

Organizer

Data Source

[Presentation] Biochemical characterization of T cell derived bronvhoconstriction2023

Author(s)

Organizer

Data Source

[Presentation] T cell-dependent steroid-resistant asthma is mediated by tyrosine kinases of costimulatory signal2022

Author(s)

Organizer

Data Source

[Presentation] Control of T cell-dependent steroid-resistant asthma model by several kinase inhibitors2022

Author(s)

Organizer

Data Source

[Presentation] 重症喘息のステロイド抵抗性とその制御2022

Ohtomo Takayuki 大友隆之

OHTOMO Takayuki 大友隆之