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Denda Tadamichi  傳田 忠道

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傳田 忠道  デンダ タダミチ

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Researcher Number 90466053
Affiliation (Current) 2025: 千葉県がんセンター(研究所), 消化器内科, 部長
Affiliation (based on the past Project Information) *help 2016 – 2019: 千葉県がんセンター(研究所), 消化器内科, 部長
Review Section/Research Field
Principal Investigator
Gastroenterology
Keywords
Principal Investigator
遺伝子 / トランスレーショナルリサーチ / 癌 / KRAS / ピロールイミダゾール含有ポリアミド / リッキドバイオプシー / 大腸がん / リキッドバイオプシー / ctDNA / KRAS変異 / PIポリアミド
  • Research Projects

    (1 results)
  • Research Products

    (37 results)
  • Co-Researchers

    (4 People)
  •  Development of highly sensitive genotyping method by blood circulating tumor DNA enrichment using PIP polyamidePrincipal Investigator

    • Principal Investigator
      Denda Tadamichi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Chiba Cancer Center (Research Institute)

All 2019 2018 2017 2016 Other

All Journal Article Presentation Other

  • [Journal Article] Phase II trial of aflibercept with FOLFIRI as a second-line treatment for Japanese patients with metastatic colorectal cancer.2019

    • Author(s)
      Denda T, Sakai D, Hamaguchi T, Sugimoto N, Ura T, Yamazaki K, Fujii H, Kajiwara T, Nakajima TE, Takahashi S, Otsu S, Komatsu Y, Nagashima F, Moriwaki T, Esaki T, Sato T, Itabashi M, Oki E, Sasaki T, Sunaga Y, Ziti-Ljajic S, Brillac C, Yoshino T.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 3 Pages: 1032-1043

    • DOI

      10.1111/cas.13943

    • NAID

      120007128072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Observational study of first-line chemotherapy including cetuximab in patients with metastatic colorectal cancer: CORAL trial.2019

    • Author(s)
      Muro K, Itabashi M, Hashida H, Masuishi T, Bando H, Denda T, Yamanaka T, Ohashi Y, Sugihara K.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 49(4) Issue: 4 Pages: 339-346

    • DOI

      10.1093/jjco/hyy189

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Exploration of potential prognostic biomarkers in aflibercept plus FOLFIRI in Japanese patients with metastatic colorectal cancer.2019

    • Author(s)
      Hamaguchi T, Denda T, Kudo T, Sugimoto N, Ura T, Yamazaki K, Fujii H, Kajiwara T, Nakajima TE, Takahashi S, Otsu S, Komatsu Y, Nagashima F, Moriwaki T, Esaki T, Sato T, Itabashi M, Oki E, Sasaki T, Chiron M, Yoshino T.
    • Journal Title

      Cancer Sci.

      Volume: 110(11) Issue: 11 Pages: 3565-3572

    • DOI

      10.1111/cas.14198

    • NAID

      120007127702

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Enrichment technique to allow early detection and monitor emergence of KRAS mutation in response to treatment.2019

    • Author(s)
      Kitagawa Y, Okumura K, Watanabe T, Tsukamoto K, Kitano S, Nankinzan R, Suzuki T, Hara T, Soda H, Denda T, Yamaguchi T, Nagase H.
    • Journal Title

      Sci Rep.

      Volume: 9 Issue: 1 Pages: 11346-11346

    • DOI

      10.1038/s41598-019-47700-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17508, KAKENHI-PROJECT-17H03602, KAKENHI-PROJECT-16K09333
  • [Journal Article] A multicentre, prospective study of plasma circulating tumour DNA test for detecting RAS mutation in patients with metastatic colorectal cancer.2019

    • Author(s)
      Bando H, Kagawa Y, Kato T, Akagi K, Denda T, Nishina T, Komatsu Y, Oki E, Kudo T, Kumamoto H, Yamanaka T, Yoshino T.
    • Journal Title

      Br J Cancer.

      Volume: 120(10) Issue: 8 Pages: 982-986

    • DOI

      10.1038/s41416-020-0766-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] A phase II trial to evaluate the efficacy of panitumumab combined with fluorouracil-based chemotherapy for metastatic colorectal cancer: the PF trial.2018

    • Author(s)
      Munemoto Y, Kanda M, Oba K, Kim HM, Takemoto H, Denda T, Nagata N, Takano N, Fukunaga M, Kataoka M, Tokunaga Y, Sakamoto J, Mishima H.
    • Journal Title

      Cancer Chemother Pharmacol.

      Volume: 81 Issue: 5 Pages: 829-838

    • DOI

      10.1007/s00280-018-3556-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333, KAKENHI-PROJECT-15H05661
  • [Journal Article] Relationship Between Thymidine Kinase 1 Expression and Trifluridine/Tipiracil Therapy in Refractory Metastatic Colorectal Cancer: A Pooled Analysis of 2 Randomized Clinical Trials.2018

    • Author(s)
      Yoshino T, Yamazaki K, Shinozaki E, Komatsu Y, Nishina T, Baba H, Tsuji A, Tsuji Y, Yamaguchi K, Sugimoto N, Denda T, Muro K, Takayama T, Esaki T, Hamamoto Y, Moriwaki T, Shimada Y, Goto M, Nakayama N, Fujii H, Tanase T, Ohtsu A
    • Journal Title

      Clin Colorectal Cancer.

      Volume: 17 Issue: 4 Pages: 719-732

    • DOI

      10.1016/j.clcc.2018.07.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Clinical Validation of Newly Developed Multiplex Kit Using Luminex xMAP Technology for Detecting Simultaneous RAS and BRAF Mutations in Colorectal Cancer: Results of the RASKET-B Study.2018

    • Author(s)
      Taniguchi H, Okamoto W, Muro K, Akagi K, Hara H, Nishina T, Kajiwara T, Denda T, Hironaka S, Kudo T, Satoh T, Yamanaka T, Abe Y, Fukushima Y, Yoshino T.
    • Journal Title

      Neoplasia.

      Volume: 20 Issue: 12 Pages: 1219-1226

    • DOI

      10.1016/j.neo.2018.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Tumor Sidedness and Enriched Gene Groups for Efficacy of First-line Cetuximab Treatment in Metastatic Colorectal Cancer.2018

    • Author(s)
      Sunakawa Y, Mogushi K, Lenz HJ, Zhang W, Tsuji A, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Segawa Y, Tanioka H, Negoro Y, Moran M, Astrow SH, Hsiang J, Stephens C, Fujii M, Ichikawa W.
    • Journal Title

      Mol Cancer Ther.

      Volume: 17 Issue: 12 Pages: 2788-2795

    • DOI

      10.1158/1535-7163.mct-18-0694

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09333, KAKENHI-PROJECT-16K10552, KAKENHI-PROJECT-18K06198
  • [Journal Article] Role of Predictive Value of the Modified Glasgow Prognostic Score for Later-line Chemotherapy in Patients With Metastatic Colorectal Cancer.2018

    • Author(s)
      suchihashi K, Ito M, Moriwaki T, Fukuoka S, Taniguchi H, Takashima A, Kumekawa Y, Kajiwara T, Yamazaki K, Esaki T, Makiyama A, Denda T, Satake H, Suto T, Sugimoto N, Katsumata K, Ishikawa T, Kashiwada T, Oki E, Komatsu Y, Okuyama H, Sakai D, Ueno H, Tamura T, Yamashita K, Kishimoto J, Shimada Y, Baba E
    • Journal Title

      Clin Colorectal Cancer.

      Volume: 17 Issue: 4 Pages: 687-697

    • DOI

      10.1016/j.clcc.2018.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Propensity Score Analysis of Regorafenib Versus Trifluridine/Tipiracil in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapy (REGOTAS): A Japanese Society for Cancer of the Colon and Rectum Multicenter Observational Study.2018

    • Author(s)
      Moriwaki T, Fukuoka S, Taniguchi H, Takashima A, Kumekawa Y, Kajiwara T, Yamazaki K, Esaki T, Makiyama C, Denda T, Satake H, Suto T, Sugimoto N, Enomoto M, Ishikawa T, Kashiwada T, Sugiyama M, Komatsu Y, Okuyama H, Baba E, Sakai D, Watanabe T, Tamura T, Yamashita K, Gosho M, Shimada Y.
    • Journal Title

      Oncologist.

      Volume: 23 Issue: 1 Pages: 7-15

    • DOI

      10.1634/theoncologist.2017-0275

    • NAID

      120007134517

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Cumulative incidence, risk factors and prognostic impact of venous thromboembolism in Japanese patients with advanced gastric cancer.2017

    • Author(s)
      Arai H, Hironaka S, Minashi K, Denda T, Shimokawa M, Yamaguchi T.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 47 Issue: 10 Pages: 942-948

    • DOI

      10.1093/jjco/hyx107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] The subgroups of the phase III RECOURSE trial of trifluridine/tipiracil (TAS-102) versus placebo with best supportive care in patients with metastatic colorectal cancer.2017

    • Author(s)
      Van Cutsem E, Mayer RJ, Laurent S, Winkler R, Gravalos C, Benavides M, Longo-Munoz F, Portales F, Ciardiello F, Siena S, Yamaguchi K, Muro K, Denda T, Tsuji Y, Makris L, Loehrer P, Lenz HJ, Ohtsu A; RECOURSE Study Group.
    • Journal Title

      Eur J Cancer.

      Volume: 90 Pages: 63-72

    • DOI

      10.1016/j.ejca.2017.10.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Phase II study of S-1 plus leucovorin in patients with metastatic colorectal cancer: Regimen of 1 week on, 1 week off.2017

    • Author(s)
      Li J, Xu R, Xu J, Denda T, Ikejiri K, Shen L, Toh Y, Shimada K, Kato T, Sakai K, Yamamoto M, Mishima H, Wang J, Baba H.
    • Journal Title

      Cancer Sci.

      Volume: 108 Issue: 10 Pages: 2045-2051

    • DOI

      10.1111/cas.13335

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09333, KAKENHI-PROJECT-16K10525
  • [Journal Article] CEA Response and Depth of Response (DpR) to Predict Clinical Outcomes of First-Line Cetuximab Treatment for Metastatic Colorectal Cancer.2017

    • Author(s)
      Sunakawa Y, Tsuji A, Denda T, Segawa Y, Negoro Y, Shimada K, Kochi M, Nakamura M, Kotaka M, Tanioka H, Takagane A, Tani S, Yamaguchi T, Watanabe T, Takeuchi M, Fujii M, Ichikawa W.
    • Journal Title

      Target Oncol.

      Volume: 12 Issue: 6 Pages: 787-794

    • DOI

      10.1007/s11523-017-0527-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Early morphological change for predicting outcome in metastatic colorectal cancer after regorafenib.2017

    • Author(s)
      Arai H, Miyakawa K, Denda T, Mizukami T, Horie Y, Izawa N, Hirakawa M, Ogura T, Tsuda T, Sunakawa Y, Nakajima TE.
    • Journal Title

      Oncotarget.

      Volume: 8 Issue: 66 Pages: 110530-110539

    • DOI

      10.18632/oncotarget.22807

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Prognostic Impact of Primary Tumor Location on Clinical Outcomes of Metastatic Colorectal Cancer Treated With Cetuximab Plus Oxaliplatin-Based Chemotherapy: A Subgroup Analysis of the JACCRO CC-05/06 Trials.2016

    • Author(s)
      Sunakawa Y, Ichikawa W, Tsuji A, Denda T, Segawa Y, Negoro Y, Shimada K, Kochi M, Nakamura M, Kotaka M, Tanioka H, Takagane A, Tani S, Yamaguchi T, Watanabe T, Takeuchi M, Fujii M, Nakajima T.
    • Journal Title

      Clin Colorectal Cancer.

      Volume: S1533-0028 Issue: 3 Pages: 30204-3

    • DOI

      10.1016/j.clcc.2016.09.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Randomized study of FOLFIRI plus either panitumumab or bevacizumab for wild-type KRAS colorectal cancer-WJOG 6210G.2016

    • Author(s)
      Shitara K, Yonesaka K, Denda T, Yamazaki K, Moriwaki T, Tsuda M, Takano T, Okuda H, Nishina T, Sakai K, Nishio K, Tokunaga S, Yamanaka T, Boku N, Hyodo I, Muro K.
    • Journal Title

      Cancer Sci.

      Volume: 107 Issue: 12 Pages: 1843-1850

    • DOI

      10.1111/cas.13098

    • NAID

      120007135107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Combined assessment of EGFR-related molecules to predict outcome of 1st-line cetuximab-containing chemotherapy for metastatic colorectal cancer.2016

    • Author(s)
      Sunakawa Y, Yang D, Moran M, Astrow SH, Tsuji A, Stephens C, Zhang W, Cao S, Takahashi T, Denda T, Shimada K, Kochi M, Nakamura M, Kotaka M, Segawa Y, Masuishi T, Takeuchi M, Fujii M, Nakajima T, Ichikawa W, Lenz HJ.
    • Journal Title

      Cancer Biol Ther.

      Volume: 17 Pages: 751-759

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Early Tumor Shrinkage and Depth of Response as Predictors of Favorable Treatment Outcomes in Patients with Metastatic Colorectal Cancer Treated with FOLFOX Plus Cetuximab (JACCRO CC-05).2016

    • Author(s)
      Tsuji A, Sunakawa Y, Ichikawa W, Nakamura M, Kochi M, Denda T, Yamaguchi T, Shimada K, Takagane A, Tani S, Kotaka M, Kuramochi H, Furushima K, Koike J, Yonemura Y, Takeuchi M, Fujii M, Nakajima T.
    • Journal Title

      Target Oncol.

      Volume: 11 Pages: 799-806

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Pharmacokinetic dose adjustment of 5-FU in modified FOLFOX7 plus bevacizumab for metastatic colorectal cancer in Japanese patients: a-JUST phase II clinical trial.2016

    • Author(s)
      Denda T, Kanda M, Morita Y, Kim HM, Kashiwada T, Matsuda C, Fujieda S, Nakata K, Murotani K, Oba K, Sakamoto J, Mishima H.
    • Journal Title

      Cancer Chemother Pharmacol.

      Volume: 78 Issue: 7 Pages: 1253-1261

    • DOI

      10.1080/15384047.2016.1178426

    • NAID

      120006220413

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Journal Article] Phase II trial of panitumumab with irinotecan as salvage therapy for patients with advanced or recurrent colorectal cancer (TOPIC study).2016

    • Author(s)
      Nishi T, Hamamoto Y, Nagase M, Denda T, Yamaguchi K, Amagai K, Miyata Y, Yamanaka Y, Yanai K, Ishikawa T, Kuroki Y, Fujii H.
    • Journal Title

      Oncol Lett.

      Volume: 11 Pages: 4049-4054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] TRICOLORE試験(大腸癌第3相試験: mFOLFOX6/CapeOX+Bev vs S-1/CPT-11+Bev)のQOL解析2019

    • Author(s)
      佐藤温,高島淳生,傳田忠道,蒲生真紀夫,高畑武功,天貝賢二,倉持英和,近藤仁,的場周一郎,有岡仁,小松嘉人,山口達郎,嶋田顕,森田智視,石岡千加史
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] TRICOLORE試験に基づいた転移を有する大腸癌に対する一次治療の費用効果分析2019

    • Author(s)
      後藤励,高島淳生,傳田忠道,蒲生真紀夫,倉持英和,天貝賢二,近藤仁,杉山克郎,中村路夫,畑中一映,石岡千加史,小松嘉人,山口達郎,嶋田顕,森田智視
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] Whole-exome sequencing in metastatic or locally advanced pancreatic cancer patients with long-term survival2019

    • Author(s)
      須藤研太郎,横井左奈,小原收,中村和貴,辻本彰子,喜多絵美里,長谷川嘉則,中山学,石井浩,傳田忠道,山口武人
    • Organizer
      第17回日本臨床腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 抗血栓薬内服者における胃ESD後のセカンドルック内視鏡についての検討2019

    • Author(s)
      石垣飛鳥,鈴木拓人,南金山理乃,北川善康,傳田忠道,山口武人
    • Organizer
      JDDW
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 抗血栓薬内服下における早期胃癌に対する内視鏡的粘膜下層剥離術のセカンドルック内視鏡に関する検討2019

    • Author(s)
      石垣飛鳥,鈴木拓人,南金山理乃,北川善康,傳田忠道,山口武人
    • Organizer
      第108回日本消化器内視鏡学会関東支部例会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] ESD 治療により診断、治療し得たDysplasiaを伴う尖圭コンジローマの一例2019

    • Author(s)
      橋本佳恵,石垣飛鳥,喜多絵美里,辻本彰子,天沼祐介,須藤研太郎,中村和貴,三梨桂子,傳田忠道,山口武人,鈴木拓人,南金山理乃,北川善康,荒木章伸,伊丹真紀子
    • Organizer
      日本消化器病学会関東支部第356回例会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 結腸直腸癌の原発部位別遺伝子プロファイル解析 GI-Screen 2013-01-CRC 付随研究2019

    • Author(s)
      水上拓郎,高橋政樹,砂川優,結城敏志,賀川義規,高島淳生,舛石俊樹,原浩樹,傳田忠道,森脇俊和,塩澤学,沖英次,岡本渉,吉野孝之,中島貴子
    • Organizer
      第57回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 微小陥凹形態を呈した十二指腸Neuroendocrine tumor の一例2019

    • Author(s)
      橋本佳恵,石垣飛鳥,辻本彰子,喜多絵美里,天沼裕介,須藤研太郎,中村和貴,三梨桂子,傳田忠道,石井浩,山口武人,鈴木拓人,南金山理乃,北川善康,川名秀忠,荒木彰伸,伊丹真紀子
    • Organizer
      日本消化器病学会関東支部第357回例会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 血中微量二本鎖核酸分子を標的とした PI ポリアミドを用いたがん遺伝子変異同定法の開発と臨床応用の検討2018

    • Author(s)
      北川善康、奥村和弘、鈴木拓人、渡部隆義、早田浩明、傳田忠道、永瀬浩喜、山口武人
    • Organizer
      日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] PIポリアミドを用いた高感度ctDNA検出技術の開発と臨床応用の検討2018

    • Author(s)
      北川善康,傳田忠道,山口武人
    • Organizer
      消化器病学会・消化器内視鏡学会・消化器外科学会・消化器がん検診学会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 血中微量二本鎖核酸分子を標的とした PI ポリアミドを用いたがん遺伝子変異同定法の開発と臨床応用の検討2017

    • Author(s)
      北川善康、奥村和弘、鈴木拓人、渡部隆義、早田浩明、傳田忠道、永瀬浩喜、山口武人
    • Organizer
      第26回日本癌病態治療研究会
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] Cetuximab併用療法耐性大腸癌に対するS-1/CPT-11/bevacizumabの第Ⅱ相試験2016

    • Author(s)
      谷岡 洋亮,辻 晃仁, 東風 貢, 高橋 孝夫, 傳田忠道, 小川 雅彰, 渡邉 貴紀, 金 浩敏, 嶋田 顕:
    • Organizer
      第54回日本癌治療学会学術集会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2016-10-20
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] 切除不能な大腸癌症例におけるセツキシマブを含む一次治療の観察研究 (CORAL)2016

    • Author(s)
      傳田忠道,室圭, 板橋道朗, 大橋靖雄, 杉原健一
    • Organizer
      第54回日本癌治療学会学術集会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2016-10-20
    • Data Source
      KAKENHI-PROJECT-16K09333
  • [Presentation] RAS野生型大腸癌における原発部位とcetuximab併用療法の予後との相関: JACCRO CC-05/062016

    • Author(s)
      砂川 優, 辻 晃仁, 傳田忠道, 嶋田 顕, 東風 貢, 中村 将人, 小高 雅人, 畝川 芳彦, 谷岡 洋亮, 根来 裕二, 山口 達郎, 竹内 正弘, 藤井 雅志, 市川 度, 中島 聰總
    • Organizer
      第54回日本癌治療学会学術集会
    • Place of Presentation
      神奈川県横浜市
    • Year and Date
      2016-10-20
    • Data Source
      KAKENHI-PROJECT-16K09333
  • []

  • 1.  渡部 隆義 (60526060)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  奥村 和弘 (80584680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  永瀬 浩喜 (90322073)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  北川 善康
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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