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Awazawa Motoharu  粟澤 元晴

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… Alternative Names

粟澤 元晴  アワザウ モトハル

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Researcher Number 90466764
Other IDs
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立国際医療研究所, 室長
Affiliation (based on the past Project Information) *help 2019 – 2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 糖尿病研究センター 分子糖尿病医学研究部 統合生理学研究室長
2018: 国立国際医療研究センター, 室長
2011: 東京大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 54040:Metabolism and endocrinology-related / Metabolomics
Except Principal Investigator
Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Pathological medical chemistry
Keywords
Principal Investigator
糖尿病 / マイクロRNA / 無汗性外胚葉形成不全症 / 脂肪肝 / 血糖 / シングルセル解析 / 熱放散 / 肥満 / 代謝 / 皮膚 … More / EDA / 肝臓 / メタボリック症候群 / STAT3 / IRS-2 / IL-6 / アディポネクチン … More
Except Principal Investigator
糖尿病 / 肥満 / 体温調節 / 代謝 / 熱放散 / 糖代謝 / シングルセル解析 / 皮膚 / Mek/Erk経路 / インスリン分泌 / Mek/Erkシグナル / 膵島 / 細胞増殖 / インスリン / 2型糖尿病 / MEK/ERKシグナル / 膵β細胞 Less
  • Research Projects

    (4 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (8 People)
  •  Re-understanding of Systemic Metabolism through Skin-mediated Thermal Regulation

    • Principal Investigator
      Ueki Kohjiro
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
    • Research Institution
      National Center for Global Health and Medicine
  •  Research of EDA and its associated moleculesPrincipal Investigator

    • Principal Investigator
      Awazawa Motoharu
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54040:Metabolism and endocrinology-related
    • Research Institution
      National Center for Global Health and Medicine
  •  Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes

    • Principal Investigator
      Ikushima Yoshiko M
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center for Global Health and Medicine
  •  アディポネクチン新規受容体の同定と,その抗糖尿病作用の解明Principal Investigator

    • Principal Investigator
      粟澤 元晴
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokyo

All 2022 2021 2019 2011

All Journal Article Presentation

  • [Journal Article] An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance2022

    • Author(s)
      Matsushita Maya、Awazawa Motoharu、Kobayashi Naoki、Ikushima Yoshiko Matsumoto、Soeda Kotaro、Tamura-Nakano Miwa、Muratani Masafumi、Kobayashi Kenta、Bl?her Matthias、Br?ning Jens C.、Ueki Kohjiro
    • Journal Title

      Cell Chemical Biology

      Volume: 29 Issue: 4 Pages: 680-689.e6

    • DOI

      10.1016/j.chembiol.2021.12.008

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09037, KAKENHI-PROJECT-18K15075
  • [Journal Article] Exploring regulatory network of metabolism through liver research2021

    • Author(s)
      Awazawa Motoharu
    • Journal Title

      Diabetology International

      Volume: 12 Issue: 4 Pages: 343-348

    • DOI

      10.1007/s13340-021-00536-z

    • NAID

      130008145819

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09037
  • [Journal Article] MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis2021

    • Author(s)
      Ikushima Yoshiko Matsumoto、Awazawa Motoharu、Kobayashi Naoki、Osonoi Sho、Takemiya Seiichi、Kobayashi Hiroshi、Suwanai Hirotsugu、Morimoto Yuichi、Soeda Kotaro、Adachi Jun、Muratani Masafumi、Charron Jean、Mizukami Hiroki、Takahashi Noriko、Ueki Kohjiro
    • Journal Title

      Diabetes

      Volume: 70 Issue: 7 Pages: 1519-1535

    • DOI

      10.2337/db20-1295

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09037, KAKENHI-PROJECT-19K16547, KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-18K15075
  • [Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage妖erived IL-6 dependent pathway2011

    • Author(s)
      Awazawa M, Ueki K, Yamauchi T, Kubota, Kadowaki T
    • Journal Title

      Cell Metabolism

      Volume: 13 Issue: 4 Pages: 401-412

    • DOI

      10.1016/j.cmet.2011.02.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-23791019
  • [Presentation] インスリン抵抗性と脂肪肝を形成をつなぐ新たな分子機構2022

    • Author(s)
      粟澤元晴
    • Organizer
      第8回肝臓と糖尿病・代謝研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09037
  • [Presentation] インスリン抵抗性と脂肪肝形成の新規メカニズム2021

    • Author(s)
      粟澤元晴
    • Organizer
      第36回日本糖尿病合併症学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K09037
  • [Presentation] 肝臓を中心とした臓器間クロストークによる代謝制御機構の解明2021

    • Author(s)
      粟澤元晴
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-19K09037
  • [Presentation] 肝臓を中心とした臓器間クロストークによる代謝制御機構の解明2021

    • Author(s)
      粟澤元晴
    • Organizer
      第64回日本糖尿病学会年次学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K21620
  • [Presentation] 糖尿病合併 NASH における血糖とインスリンによる腸内細菌叢の変化2019

    • Author(s)
      添田 光太郎,小林 直樹,生島 芳子,笹子 敬洋,戸田 郷太郎,粟澤 元晴, 門脇 孝,植木 浩二郎
    • Organizer
      第33日本糖尿病・肥満動物学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-16K19067
  • [Presentation] 膵β細胞制御におけるMek/Erkシグナルの役割の解明2019

    • Author(s)
      生島 芳子,小林 直樹,粟澤 元晴,諏訪内浩紹,添田光太郎,村谷 匡史,高橋 倫子,植木浩二郎
    • Organizer
      第62回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-16K19067
  • [Presentation] Mek/Erkシグナルは膵β細胞の量と分泌能を制御する2019

    • Author(s)
      生島芳子、小林直樹、粟澤元晴、竹宮聖一、諏訪内浩紹、 添田光太郎、守本祐一、村谷匡史、高橋倫子、植木浩二郎
    • Organizer
      第33日本糖尿病・肥満動物学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-16K19067
  • [Presentation] アディポネクチンによる新たなインスリン感受性亢進作用の同定2011

    • Author(s)
      粟澤元晴
    • Organizer
      日本糖尿病学会
    • Place of Presentation
      札幌
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-23791019
  • [Presentation] アディポネクチンによる抗糖尿病作用の新規メカニズム2011

    • Author(s)
      粟澤元晴
    • Organizer
      日本糖尿病・肥満動物学会
    • Place of Presentation
      東京
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PROJECT-23791019
  • 1.  Ueki Kohjiro (00396714)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 2.  Ikushima Yoshiko M (00571366)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  Kobayashi Naoki (80750728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  Suwanai Hirotsugu (60624939)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  Muratani Masafumi (50730199)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  門脇 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  山内 敏正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  窪田 直人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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