Awazawa Motoharu 粟澤元晴

… Alternative Names

粟澤元晴アワザウモトハル

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Researcher Number	90466764
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立国際医療研究センター, 研究所, 糖尿病研究センター分子糖尿病医学研究部統合生理学研究室長
Affiliation (based on the past Project Information) *help	2019 – 2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 糖尿病研究センター分子糖尿病医学研究部統合生理学研究室長 2018: 国立国際医療研究センター, 室長 2011: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics Except Principal Investigator Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Pathological medical chemistry
Keywords	Principal Investigator 糖尿病 / マイクロRNA / 無汗性外胚葉形成不全症 / 脂肪肝 / 血糖 / シングルセル解析 / 熱放散 / 肥満 / 代謝 / 皮膚 … More / EDA / 肝臓 / メタボリック症候群 / STAT3 / IRS-2 / IL-6 / アディポネクチン … More Except Principal Investigator 糖尿病 / 肥満 / 体温調節 / 代謝 / 熱放散 / 糖代謝 / シングルセル解析 / 皮膚 / Mek/Erk経路 / インスリン分泌 / Mek/Erkシグナル / 膵島 / 細胞増殖 / インスリン / 2型糖尿病 / MEK/ERKシグナル / 膵β細胞 Less

Re-understanding of Systemic Metabolism through Skin-mediated Thermal Regulation
- Principal Investigator
  
  Ueki Kohjiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  National Center for Global Health and Medicine
Research of EDA and its associated moleculesPrincipal Investigator
- Principal Investigator
  
  Awazawa Motoharu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  National Center for Global Health and Medicine
Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes
- Principal Investigator
  
  Ikushima Yoshiko M
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Center for Global Health and Medicine
アディポネクチン新規受容体の同定と,その抗糖尿病作用の解明Principal Investigator
- Principal Investigator
  
  粟澤元晴
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

All 2022 2021 2019 2011

All Journal Article Presentation

[Journal Article] An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance2022
- Author(s)
  Matsushita Maya、Awazawa Motoharu、Kobayashi Naoki、Ikushima Yoshiko Matsumoto、Soeda Kotaro、Tamura-Nakano Miwa、Muratani Masafumi、Kobayashi Kenta、Bl?her Matthias、Br?ning Jens C.、Ueki Kohjiro
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 29 Issue: 4 Pages: 680-689.e6
- DOI
  10.1016/j.chembiol.2021.12.008
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09037, KAKENHI-PROJECT-18K15075
[Journal Article] Exploring regulatory network of metabolism through liver research2021
- Author(s)
  Awazawa Motoharu
- Journal Title
  
  Diabetology International
  
  Volume: 12 Issue: 4 Pages: 343-348
- DOI
  10.1007/s13340-021-00536-z
- NAID
  130008145819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09037
[Journal Article] MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis2021
- Author(s)
  Ikushima Yoshiko Matsumoto、Awazawa Motoharu、Kobayashi Naoki、Osonoi Sho、Takemiya Seiichi、Kobayashi Hiroshi、Suwanai Hirotsugu、Morimoto Yuichi、Soeda Kotaro、Adachi Jun、Muratani Masafumi、Charron Jean、Mizukami Hiroki、Takahashi Noriko、Ueki Kohjiro
- Journal Title
  
  Diabetes
  
  Volume: 70 Issue: 7 Pages: 1519-1535
- DOI
  10.2337/db20-1295
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09037, KAKENHI-PROJECT-19K16547, KAKENHI-PROJECT-20K07280, KAKENHI-PROJECT-18K15075
[Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage妖erived IL-6 dependent pathway2011
- Author(s)
  Awazawa M, Ueki K, Yamauchi T, Kubota, Kadowaki T
- Journal Title
  
  Cell Metabolism
  
  Volume: 13 Issue: 4 Pages: 401-412
- DOI
  10.1016/j.cmet.2011.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20229008, KAKENHI-PROJECT-21390278, KAKENHI-PROJECT-23791019
[Presentation] インスリン抵抗性と脂肪肝を形成をつなぐ新たな分子機構2022
- Author(s)
  粟澤元晴
- Organizer
  第8回肝臓と糖尿病・代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09037
[Presentation] インスリン抵抗性と脂肪肝形成の新規メカニズム2021
- Author(s)
  粟澤元晴
- Organizer
  第36回日本糖尿病合併症学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09037
[Presentation] 肝臓を中心とした臓器間クロストークによる代謝制御機構の解明2021
- Author(s)
  粟澤元晴
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K09037
[Presentation] 肝臓を中心とした臓器間クロストークによる代謝制御機構の解明2021
- Author(s)
  粟澤元晴
- Organizer
  第64回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21620
[Presentation] 糖尿病合併 NASH における血糖とインスリンによる腸内細菌叢の変化2019
- Author(s)
  添田光太郎，小林直樹，生島芳子，笹子敬洋，戸田郷太郎，粟澤元晴，門脇孝，植木浩二郎
- Organizer
  第33日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] 膵β細胞制御におけるMek/Erkシグナルの役割の解明2019
- Author(s)
  生島芳子，小林直樹，粟澤元晴，諏訪内浩紹，添田光太郎，村谷匡史，高橋倫子，植木浩二郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] Mek/Erkシグナルは膵β細胞の量と分泌能を制御する2019
- Author(s)
  生島芳子、小林直樹、粟澤元晴、竹宮聖一、諏訪内浩紹、添田光太郎、守本祐一、村谷匡史、高橋倫子、植木浩二郎
- Organizer
  第33日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] アディポネクチンによる新たなインスリン感受性亢進作用の同定2011
- Author(s)
  粟澤元晴
- Organizer
  日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23791019
[Presentation] アディポネクチンによる抗糖尿病作用の新規メカニズム2011
- Author(s)
  粟澤元晴
- Organizer
  日本糖尿病・肥満動物学会
- Place of Presentation
  東京
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23791019

1. Ueki Kohjiro (00396714)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. Ikushima Yoshiko M (00571366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. Kobayashi Naoki (80750728)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. Suwanai Hirotsugu (60624939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Muratani Masafumi (50730199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 門脇孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 山内敏正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 窪田直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Awazawa Motoharu 粟澤 元晴

粟澤 元晴 アワザウ モトハル

Research Projects

Research Products

Co-Researchers

Re-understanding of Systemic Metabolism through Skin-mediated Thermal Regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research of EDA and its associated moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アディポネクチン新規受容体の同定と,その抗糖尿病作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An antisense transcript transcribed from Irs2 locus contributes to the pathogenesis of hepatic steatosis in insulin resistance2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exploring regulatory network of metabolism through liver research2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] MEK/ERK Signaling in β-Cells Bifunctionally Regulates β-Cell Mass and Glucose-Stimulated Insulin Secretion Response to Maintain Glucose Homeostasis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage妖erived IL-6 dependent pathway2011

Author(s)

Journal Title

DOI

Data Source

[Presentation] インスリン抵抗性と脂肪肝を形成をつなぐ新たな分子機構2022

Author(s)

Organizer

Data Source

[Presentation] インスリン抵抗性と脂肪肝形成の新規メカニズム2021

Author(s)

Organizer

Data Source

[Presentation] 肝臓を中心とした臓器間クロストークによる代謝制御機構の解明2021

Author(s)

Organizer

Data Source

[Presentation] 肝臓を中心とした臓器間クロストークによる代謝制御機構の解明2021

Author(s)

Organizer

Data Source

[Presentation] 糖尿病合併 NASH における血糖とインスリンによる腸内細菌叢の変化2019

Author(s)

Organizer

Data Source

[Presentation] 膵β細胞制御におけるMek/Erkシグナルの役割の解明2019

Author(s)

Organizer

Data Source

[Presentation] Mek/Erkシグナルは膵β細胞の量と分泌能を制御する2019

Author(s)

Organizer

Data Source

[Presentation] アディポネクチンによる新たなインスリン感受性亢進作用の同定2011

Author(s)

Awazawa Motoharu 粟澤元晴

粟澤元晴アワザウモトハル