Izawa Yoshikane 伊澤良兼

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IZAWA Yoshikane 伊澤良兼

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Researcher Number	90468471
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師
Affiliation (based on the past Project Information) *help	2025: 慶應義塾大学, 医学部(信濃町), 講師 2018 – 2023: 慶應義塾大学, 医学部(信濃町), 講師 2017: 慶應義塾大学, 医学部, 助教 2014: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology Except Principal Investigator Basic Section 46030:Function of nervous system-related / Basic Section 52020:Neurology-related / Neurology
Keywords	Principal Investigator β１インテグリン / neurovascular unit / 血管内皮細胞 / 脳血管障害 / タイトジャンクション / 血液脳関門 / 血管透過性 / 血管内皮 / 脳出血 / β1インテグリン … More / 脳卒中 / 二光子顕微鏡 / 凝固因子 / トロンビン / 脳虚血 / 脳小血管病 / 遺伝性脳小血管病 / Neurovascular unit / 血管内皮障害 / 虚血性神経障害 / 脳梗塞 / 神経分子病態学 / 脳神経疾患 / 神経科学 / シグナル伝達 / 内皮透過性 / 脳浮腫 … More Except Principal Investigator アストロサイト / 脳虚血 / Neurovascular unit / 脳微小循環 / ペントースリン酸経路 / アストログリア / 脱髄 / 髄鞘 / オリゴデンドロサイト前駆細胞 / NG2グリア / オリゴデンドロサイト / 神経科学 / オプトジェネティクス / 脳微小塞栓 / ペリサイト / 光遺伝学 / ヒトiPSC / 14Cグルコース / 脊髄運動ニューロン / 代謝コンパートメント / 脳梗塞 / ヒトiPS細胞 / ニューロン / ミクログリア / glycolysis / ER stress / TLR4 / LPS / PPP / Keap1/Nrf2 / astroglia / ケトン体 / 酸化ストレス / 高血糖 / 認知症 / 糖尿病 Less

HANAC症候群におけるiPS細胞樹立とβ１インテグリンシグナル作動薬による治療法の確立Principal Investigator
- Principal Investigator
  
  伊澤良兼
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Keio University
Evaluation of the regulation mechanism of NG2 glia and remyelination under impaired conditions of the central nervous system
- Principal Investigator
  
  Unekawa Miyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Keio University
脳血管内皮透過性制御機構の解明による新規神経疾患治療法の確立Principal Investigator
- Principal Investigator
  
  伊澤良兼
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Keio University
Mechanisms of microvascular flow regulation in neurovascular coupling and responsiveness to ischemia by using optogenetics
- Principal Investigator
  
  Tomita Yutaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Keio University
A novel treatment of cerebral infarction with neuroprotective astrocytes induced by inflammatory microglia
- Principal Investigator
  
  TAKAHASHI Shinichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Keio University
beta1 integrin-pMLC endothelial permeability regulatory signaling as a novel therapeutic approach for neurological diseasesPrincipal Investigator
- Principal Investigator
  
  IZAWA Yoshikane
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Keio University
Elucidation of novel beta 1 integrin-dependent mechanisms regulating vascular permeabilityPrincipal Investigator
- Principal Investigator
  
  Izawa Yoshikane
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Keio University
Astrocytic neuroprotective mechanism against diabetic encephalopathy through metabolic stress response
- Principal Investigator
  
  TAKAHASHI Shinichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020 2019 2018 2017 2013 2012

All Journal Article Presentation

[Journal Article] Striatal blood flow changes by middle cerebral artery occlusion and its effect on neurological deficits in mice.2024
- Author(s)
  Unekawa M., Tsukada N., Takizawa T., Tomita Y., Nakahara J., Izawa Y.
- Journal Title
  
  Microcirculation
  
  Volume: － Issue: 6
- DOI
  10.1111/micc.12861
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443
[Journal Article] Acceleration of the Development of Microcirculation Embolism in the Brain due to Capillary Narrowing2023
- Author(s)
  Murata Juri、Unekawa Miyuki、Kudo Yuya、Kotani Maho、Kanno Iwao、Izawa Yoshikane、Tomita Yutaka、Tanaka Kenji F.、Nakahara Jin、Masamoto Kazuto
- Journal Title
  
  Stroke
  
  Volume: 54 Issue: 8 Pages: 2135-2144
- DOI
  10.1161/strokeaha.122.042416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07443, KAKENHI-PROJECT-22K07317, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443, KAKENHI-PLANNED-20H05896
[Journal Article] Effect of Goreisan, a Japanese Traditional Medicine, on Cortical Spreading Depolarization in Mice.2022
- Author(s)
  Iba C, Unekawa M, Izawa Y, Nakahara J, Takizawa T
- Journal Title
  
  Int J Mol Sci
  
  Volume: 23 Issue: 22 Pages: 13803-13803
- DOI
  10.3390/ijms232213803
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06443
[Journal Article] Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice.2022
- Author(s)
  Unekawa M, Tomita Y, Masamoto K, Kanno I, Nakahara J, Izawa Y
- Journal Title
  
  Brain Res
  
  Volume: 1792 Pages: 148023-148023
- DOI
  10.1016/j.brainres.2022.148023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443, KAKENHI-PROJECT-21K07443
[Journal Article] Time Series Tracking of Cerebral Microvascular Adaptation to Hypoxia and Hyperoxia Imaged with Repeated In Vivo Two-Photon Microscopy.2021
- Author(s)
  Sugashi T., Niizawa T., Suzuki H., Takuwa H., Unekawa M., Tomita Y., Kanno I., Masamoto K.
- Journal Title
  
  Adv. Exp. Med. Biol.
  
  Volume: 1269 Pages: 323-327
- DOI
  10.1007/978-3-030-48238-1_51
- ISBN
  9783030482367, 9783030482381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-21K06443
[Journal Article] Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 22020
- Author(s)
  Tang Chunhua、Unekawa Miyuki、Shibata Mamoru、Tomita Yutaka、Izawa Yoshikane、Sugimoto Hiroki、Ikeda Keiko、Kawakami Kiyoshi、Suzuki Norihiro、Nakahara Jin
- Journal Title
  
  Cephalalgia
  
  Volume: 40 Issue: 11 Pages: 1177-1190
- DOI
  10.1177/0333102420929028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07849, KAKENHI-PROJECT-20K06929, KAKENHI-PROJECT-19K17018
[Journal Article] Neuroimaging pattern and pathophysiology of cerebellar stroke-like lesions in MELAS with m.3243A>G mutation: a case report2020
- Author(s)
  Oyama M, Iizuka T, Nakahara J, Izawa Y.
- Journal Title
  
  BMC Neurol
  
  Volume: 20 Issue: 1
- DOI
  10.1186/s12883-020-01748-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17018
[Journal Article] β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.2018
- Author(s)
  Izawa Y, Gu YH, Osada T, Kanazawa M, Hawkins BT, Koziol JA, Papayannopoulou T, Spatz M, Del Zoppo GJ.
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: 38 Issue: 4 Pages: 641-658
- DOI
  10.1177/0271678x17722108
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16129, KAKENHI-PROJECT-15K19478
[Journal Article] "Neuro-protective role of astroglia in Parkinson disease by reducing oxidative stress through dopamine-induced activation of pentose-phosphate pathway2018
- Author(s)
  Mahima K, Takahashi S, Minami K, Izawa Y, Abe T, Tsukada N, Hishiki T, Suematsu M, Kajimura M, Suzuki N
- Journal Title
  
  ASN neuro
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16129
[Journal Article] NVUにおけるBBBの役割とcellular metabolic compartment2013
- Author(s)
  髙橋愼一、安部貴人、伊澤良兼、飯泉琢矢、鈴木則宏
- Journal Title
  
  脳循環代謝
  
  Volume: 24 Pages: 75-82
- Data Source
  KAKENHI-PROJECT-24591276
[Journal Article] Astroglial pentose phosphate pathway rates in response to high-glucose environments.2012
- Author(s)
  Shinichi Takahashi, Yoshikane Izawa, Norihiro Suzuki
- Journal Title
  
  ASN NEURO
  
  Volume: 4(2) Issue: 2
- DOI
  10.1042/an20120002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591276
[Journal Article] Effects of fluctuating glucose concentrations on oxidative metabolism of glucose in cultured neurons and astroglia.2012
- Author(s)
  Shinichi Takahashi, Yoshikane Izawa, Norihiro Suzuki
- Journal Title
  
  Journal of Diabetes Mellitus
  
  Volume: 2(1) Issue: 01 Pages: 19-26
- DOI
  10.4236/jdm.2012.21004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591276
[Journal Article] Astrogliopathy as a loss of astroglial protective function against glycoxidative stress under hyperglycemia2012
- Author(s)
  Shinichi Takahashi, Yoshikane Izawa, Norihiro Suzuki
- Journal Title
  
  Rinsho Shinkeigaku
  
  Volume: 52 Issue: 1 Pages: 41-51
- DOI
  10.5692/clinicalneurol.52.41
- NAID
  130004505025
- ISSN
  0009-918X, 1882-0654
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591276
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex in stroke model mice.2023
- Author(s)
  Unekawa M., Tsukada N., Takizawa T., Tomita Y., Nakahara J., Izawa Y.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Pathophysiology and Management of Stroke. From an Internist's Perspective2023
- Author(s)
  伊澤良兼
- Organizer
  微小循環学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07443
[Presentation] ミクログリアの個性を示す画像化手法の提案：生体二光子顕微鏡による検討2023
- Author(s)
  工藤雄也, 須貸琢磨, 結城浩弥, 曽我直人, 畝川美悠紀, 冨田裕, 伊澤良兼, 中原仁, 菅野巖, 正本和人.
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Capillary constriction enhances microcirculation embolism in the mouse cortex.2023
- Author(s)
  Kudo Y, Murata J, Unekawa M, Kanno I, Izawa Y, Tomita Y, Tanaka KF, Nakahara J, Masamoto K
- Organizer
  US-Japan Joint Workshop on the Neurovascular Unit 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Capillary constriction enhances microcirculation embolism in the mouse cortex.2023
- Author(s)
  Kudo Y, Murata J, Unekawa M, Kanno I, Izawa Y, Tomita Y, Tanaka KF, Nakahara J, Masamoto K
- Organizer
  US-Japan Joint Workshop on the Neurovascular Unit 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex by transient occlusion of middle cerebral artery in mice.2023
- Author(s)
  Unekawa M, Takizawa T, Tomita Y, Nakahara J, Izawa Y
- Organizer
  第48回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Quantitative characterization of the microglial response to chronic hypoxia in the mouse cortex.2023
- Author(s)
  Kudo Y., Sugashi T., Yuki H., Soga N., Unekawa M., Tomita Y., Izawa Y., Nakahara J., Kanno I., Masamoto K.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex in stroke model mice.2023
- Author(s)
  Unekawa M., Tsukada N., Takizawa T., Tomita Y., Nakahara J., Izawa Y.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] ミクログリアの個性を示す画像化手法の提案：生体二光子顕微鏡による検討2023
- Author(s)
  工藤雄也, 須貸琢磨, 結城浩弥, 曽我直人, 畝川美悠紀, 冨田裕, 伊澤良兼, 中原仁, 菅野巖, 正本和人
- Organizer
  第66回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流変化と虚血・梗塞巣の形成2023
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第48回日本脳卒中会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流変化と虚血・梗塞巣の形成2023
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第48回日本脳卒中会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Hemodynamics and infarct formation at the striatum and cerebral cortex by transient occlusion of middle cerebral artery in mice2023
- Author(s)
  Unekawa M, Takizawa T, Tomita Y, Nakahara J, Izawa Y
- Organizer
  第48回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Quantitative characterization of the microglial response to chronic hypoxia in the mouse cortex.2023
- Author(s)
  Kudo Y., Sugashi T., Yuki H., Soga N., Unekawa M., Tomita Y., Izawa Y., Nakahara J., Kanno I., Masamoto K.
- Organizer
  31st International Symposium on Cerebral Blood Flow and Metabolism
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Effects of goreisan, an herbal medicine, on cortical spreading depolarization.2022
- Author(s)
  Iba C, Unekawa M, Izawa Y, Nakahara J, Takizawa T
- Organizer
  64th Annual Scientific Meeting of the American Headache Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流動態と梗塞形成2022
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 脳微小血管の収縮による微小塞栓の形成2022
- Author(s)
  工藤雄也, 村田樹里, 小谷真穂, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] 脳微小血管の収縮による微小塞栓の形成2022
- Author(s)
  工藤雄也, 村田樹里, 小谷真穂, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] 塞栓糸を用いた中大脳動脈一過性閉塞術による大脳皮質および線条体の血流動態と梗塞形成2022
- Author(s)
  畝川美悠紀, 塚田直己, 滝沢翼, 冨田裕, 中原仁, 伊澤良兼
- Organizer
  第65回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] オプトジェネティクスを用いた脳微小血管の操作2021
- Author(s)
  小谷真穂, 村田樹里, 大石光洋, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第25回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Imaging of Cerebral Microcirculation and Expectations for Biomedical Engineering2021
- Author(s)
  Tomita Y, Unekawa M, Izawa Y, Masamoto K, Kanno I, Nakahara J
- Organizer
  第46回日本微小循環学会総会
- Data Source
  KAKENHI-PROJECT-19K17018
[Presentation] 喫煙が皮質拡延性脱分極に及ぼす影響について2021
- Author(s)
  滝沢翼, 畝川美悠紀, 伊庭知里, 加川志津子, 渡邊成美, 中山真吾, 桜井香, 宮崎直己, 石田典之, 竹村亮, 柴田護, 伊澤良兼, 中鉢正太郎, 福永興壱, 中原仁
- Organizer
  第64回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] Imaging of Cerebral Microcirculation and Expectations for Biomedical Engineering2021
- Author(s)
  Tomita Y., Unekawa M., Izawa Y., Masamoto K., Kanno I., Nakahara J.
- Organizer
  第46回日本微小循環学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Vasoconstriction and hypoperfusion induced by photoactivation of the ChR2-expressing vascular cells.2021
- Author(s)
  冨田裕, 村田樹里, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巌, 田中謙二, 正本和人, 中原仁
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K06443
[Presentation] オプトジェネティクスを用いた脳微小血管の操作2021
- Author(s)
  小谷真穂, 村田樹里, 大石光洋, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巖, 冨田裕, 田中謙二, 中原仁, 正本和人
- Organizer
  第25回酸素ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Vasoconstriction and hypoperfusion induced by photoactivation of the ChR2-expressing vascular cells.2021
- Author(s)
  冨田裕, 村田樹里, 畠山菜緒, 畝川美悠紀, 伊澤良兼, 菅野巌, 田中謙二, 正本和人, 中原仁
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Analysis of red blood cell velocity in intraparenchymal capillaries and arterial diameter in mice.2020
- Author(s)
  冨田裕, 畝川美悠紀, 伊澤良兼, 正本和人, 菅野巌, 中原仁
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K17018
[Presentation] Analysis of red blood cell velocity in intraparenchymal capillaries and arterial diameter in mice.2020
- Author(s)
  冨田裕, 畝川美悠紀, 伊澤良兼, 正本和人, 菅野巌, 中原仁.
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K06929
[Presentation] Keap1/Nrf2 System-dependent Astroglial Neuroprotection Against Dopamine2019
- Author(s)
  Shinichi Takahashi, Kyoko Mahima, Kazushi Minami, Yoshikane Izawa, Takato Abe, Naoki Tsukada, Takako Hishiki, Mayumi Kajimura, Norihiro Suzuki
- Organizer
  BRAIN & BRAIN PET 2019
- Data Source
  KAKENHI-PROJECT-19K08002
[Presentation] Neurovascular unit という微小世界からみた神経内科の実臨床2018
- Author(s)
  伊澤良兼
- Organizer
  第61回日本脳循環代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16129
[Presentation] β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.2018
- Author(s)
  伊澤良兼
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16129
[Presentation] β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.2018
- Author(s)
  Izawa Y, Gu YH, Osada T, Kanazawa M, Hawkins BT, Koziol JA, Papayannopoulou T, Spatz M, Del Zoppo GJ.
- Organizer
  第59回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-17K16129
[Presentation] 「ミエリンマップ」を用いた無症候性大脳白質病変における髄鞘障害の検討2017
- Author(s)
  伊澤良兼　髙橋愼一　中原仁　谷川万里子　陣崎雅弘　中村雅也　岡野栄之　鈴木則宏
- Organizer
  第60回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16129
[Presentation] β1-integrin modulates cerebral microvascular tight junction expression and permeability2017
- Author(s)
  Izawa Y, Gu YH, Osada T, Kanazawa M, Hawkins BT, Koziol JA, Papayannopoulou T, Spatz M, Del Zoppo GJ.
- Organizer
  第60回日本脳循環代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16129
[Presentation] β1-integrin-matrix interactions modulate cerebral microvessel endothelial cell tight junction expression and permeability.2017
- Author(s)
  Izawa Y, Gu YH, Osada T, Kanazawa M, Hawkins BT, Koziol JA, Papayannopoulou T, Spatz M, Del Zoppo GJ.
- Organizer
  8th Korean-Japan Joint Stroke Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16129

1. Unekawa Miyuki (10548481)

# of Collaborated Projects: 4 results

# of Collaborated Products: 29 results
2. TAKAHASHI Shinichi (20236285)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. Tomita Yutaka (60276251)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
4. 滝沢翼 (30778874)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. 塚田直己 (80868563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. ABE Takato (30365233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 森本悟 (00816952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 馬島恭子 (30812440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 岡野栄之 (60160694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 阿部貴人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 柴田護

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Izawa Yoshikane 伊澤 良兼

IZAWA Yoshikane 伊澤 良兼

Research Projects

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HANAC症候群におけるiPS細胞樹立とβ１インテグリンシグナル作動薬による治療法の確立Principal Investigator

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Evaluation of the regulation mechanism of NG2 glia and remyelination under impaired conditions of the central nervous system

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脳血管内皮透過性制御機構の解明による新規神経疾患治療法の確立Principal Investigator

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Mechanisms of microvascular flow regulation in neurovascular coupling and responsiveness to ischemia by using optogenetics

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A novel treatment of cerebral infarction with neuroprotective astrocytes induced by inflammatory microglia

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beta1 integrin-pMLC endothelial permeability regulatory signaling as a novel therapeutic approach for neurological diseasesPrincipal Investigator

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Elucidation of novel beta 1 integrin-dependent mechanisms regulating vascular permeabilityPrincipal Investigator

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Astrocytic neuroprotective mechanism against diabetic encephalopathy through metabolic stress response

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[Journal Article] Striatal blood flow changes by middle cerebral artery occlusion and its effect on neurological deficits in mice.2024

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[Journal Article] Acceleration of the Development of Microcirculation Embolism in the Brain due to Capillary Narrowing2023

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[Journal Article] Effect of Goreisan, a Japanese Traditional Medicine, on Cortical Spreading Depolarization in Mice.2022

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[Journal Article] Close association between spreading depolarization and development of infarction under experimental ischemia in anesthetized male mice.2022

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[Journal Article] Time Series Tracking of Cerebral Microvascular Adaptation to Hypoxia and Hyperoxia Imaged with Repeated In Vivo Two-Photon Microscopy.2021

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[Journal Article] Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 22020

Izawa Yoshikane 伊澤良兼

IZAWA Yoshikane 伊澤良兼