Sato Wakiro 佐藤和貴郎

… Alternative Names

佐藤和貴郎サトウワキロウ

SATO Wakiro 佐藤和貴郎

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Researcher Number	90469990
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立精神・神経医療研究センター, トランスレーショナル・メディカルセンター, 室長
Affiliation (based on the past Project Information) *help	2024 – 2025: 国立研究開発法人国立精神・神経医療研究センター, トランスレーショナル・メディカルセンター, 室長 2018 – 2022: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所免疫研究部, 室長 2009: National Center of Neurology and Psychiatry, 免疫研究, 厚生科学研究員 2009: 精神神経セ, 研究員 2008: National Center of Neurology and Psychiatry, 神経研究所・免疫研究部, 厚生科学研究員
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator Medium-sized Section 51:Brain sciences and related fields / Medium-sized Section 52:General internal medicine and related fields / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator IL-17 / 多勢性硬化症 / 脳脊髄液 / CD180 / CCR2 / ケモカイン受容体 / B細胞 / Th17細胞 / 多発性硬化症 / 神経病態免疫学 … More Except Principal Investigator … More Eomes陽性Th細胞 / NRP1陽性Th細胞 / 神経免疫 / Th17細胞 / 甲状腺ホルモン / EAE / 神経・内分泌・免疫制御 / 神経・免疫・内分泌連関 / 中枢神経慢性炎症 / 神経・免疫・内分泌相関 / 内分泌性制御因子 / Eomes+ Th細胞 / プロラクチン / 環境因子 / 内分泌性免疫制御因子 / 免疫性神経疾患 / 多様性 / 抗自律神経節アセチルコリン受容体抗体 / 自律神経外障害 / 小児神経 / サルコイドーシス / 膠原病 / 能動免疫 / 自律神経節アセチルコリン受容体 / 自律神経障害 / 動物モデル / 自己抗体 / 自律神経節 / 自己免疫性自律神経節障害 Less

Neuroinflammatory and degenerative pathogenesis mediated by new T cell subsets
- Principal Investigator
  
  山村隆
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 51:Brain sciences and related fields
- Research Institution
  National Center of Neurology and Psychiatry
Multidisciplinary analysis of heterogeneity in autoimmune autonomic ganglionopathy
- Principal Investigator
  
  Nakane Shunya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nippon Medical School
  Kumamoto University
Cross-talk between endocrine and environmental factors in neuroimmune disorders
- Principal Investigator
  
  Yamamura Takashi
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  National Center of Neurology and Psychiatry
Interaction between Th17 cells and B cells in the pathogenesis of multiple sclerosisPrincipal Investigator
- Principal Investigator
  
  SATO Wakiro
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry

All 2023 2022 2021 2020 2019 2018 2009 2008

All Journal Article Presentation Book Patent

[Book] Annual Review 神経2019 （鈴木則宏/荒木信夫/宇川義一/桑原　聡/塩川芳昭編） 7.脱髄・免疫性疾患の1.腸内細菌叢と多発性硬化症2019
- Author(s)
  山村　隆, 佐藤和貴郎
- Total Pages
  327
- Publisher
  中外医学社
- ISBN
  9784498328303
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] First-in-human clinical trial of the NKT cell-stimulatory glycolipid OCH in multiple sclerosis2023
- Author(s)
  Sato Wakiro、Noto Daisuke、Araki Manabu、Okamoto Tomoko、Lin Youwei、Yamaguchi Hiromi、Kadowaki-Saga Ryoko、Kimura Atsuko、Kimura Yukio、Sato Noriko、Ishizuka Takami、Nakamura Harumasa、Miyake Sachiko、Yamamura Takashi
- Journal Title
  
  Therapeutic Advances in Neurological Disorders
  
  Volume: 16
- DOI
  10.1177/17562864231162153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04045, KAKENHI-PROJECT-21H02964
[Journal Article] Ratio of lymphocyte to monocyte area under the curve as a novel predictive factor for severe infection in multiple sclerosis2023
- Author(s)
  Takahashi Junichiro、Okamoto Tomoko、Lin Youwei、Saika Reiko、Katsumoto Atsuko、Sato Wakiro、Yamamura Takashi、Takahashi Yuji
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14
- DOI
  10.3389/fimmu.2023.1133444
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease.2022
- Author(s)
  Raveney BJ, El-Darawish Y, Sato W, Arinuma Y, Yamaoka K, Hori S, Yamamura T, Oki S
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 14 Issue: 10 Pages: 1-20
- DOI
  10.15252/emmm.202215864
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19422, KAKENHI-PLANNED-22H05191, KAKENHI-PROJECT-18H04045, KAKENHI-PROJECT-21H04801, KAKENHI-PROJECT-20K07775, KAKENHI-PROJECT-20K07895
[Journal Article] Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis2021
- Author(s)
  Raveney Ben J. E.、Sato Wakiro、Takewaki Daiki、Zhang Chenyang、Kanazawa Tomomi、Lin Youwei、Okamoto Tomoko、Araki Manabu、Kimura Yukio、Sato Noriko、Sano Terunori、Saito Yuko、Oki Shinji、Yamamura Takashi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 11 Pages: 2021818118-2021818118
- DOI
  10.1073/pnas.2021818118
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07775, KAKENHI-PROJECT-20K07895, KAKENHI-PROJECT-20K16294, KAKENHI-PROJECT-18H04045
[Journal Article] Th1-CD11c+ B cell axis associated with response to plasmapheresis in multiple sclerosis2021
- Author(s)
  Kimura, K., Y. Lin, H. Yamaguchi, W. Sato, D. Takewaki, M. Minote, Y. Doi, T. Okamoto, R. Takahashi, T. Kondo, and T. Yamamura
- Journal Title
  
  Ann Neurol
  
  Volume: 90 Issue: 4 Pages: 595-611
- DOI
  10.1002/ana.26202
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] Skewing of the B cell receptor repertoire in myaligic encephalomyelitis/chronic fatigue syndrome2021
- Author(s)
  Sato, W., H. Ono, T. Matsutani, M. Nakamura, I. Shin, K. Amano, R. Suzuki, and T. Yamamura
- Journal Title
  
  Brain Behav Immun
  
  Volume: 95 Pages: 245-255
- DOI
  10.1016/j.bbi.2021.03.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis2020
- Author(s)
  Takewaki D, Suda W, Sato W, Takayasu L, Kumar N, Kimura K, Kaga N, Mizuno T, Miyake S, Hattori M, Yamamura T
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 117 Issue: 36 Pages: 22402-22412
- DOI
  10.1073/pnas.2011703117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-18H04045
[Journal Article] Gut microbiota-dependent CCR9+CD4+ T cells are altered in secondary progressive multiple sclerosis2019
- Author(s)
  Kadowaki, A., R. Saga, Y. Lin, W. Sato, and T. Yamamura
- Journal Title
  
  Brain
  
  Volume: 142(4) Issue: 4 Pages: 916-931
- DOI
  10.1093/brain/awz012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] Multiple sclerosis: Possibility of a gut environment-induced disease2019
- Author(s)
  Sato W, Yamamura T
- Journal Title
  
  Neurochem Int
  
  Volume: 130 Pages: 104517-104517
- DOI
  10.1016/j.neuint.2019.104475
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] 腸内細菌と多発性硬化症2018
- Author(s)
  佐藤和貴郎, 山村隆
- Journal Title
  
  神経内科
  
  Volume: 89（2） Pages: 186-191
- Data Source
  KAKENHI-PROJECT-18H04045
[Journal Article] 多発性硬化症におけるTh17細胞とB細胞の相互作用の解析2008
- Author(s)
  佐藤和貴
- Journal Title
  
  日本多発性硬化症協会ニュースレター No.32
  
  Pages: 1-4
- Data Source
  KAKENHI-PROJECT-20790632
[Journal Article] 多発性硬化症におけるTh17細胞とB細胞の相互作用の解析2008
- Author(s)
  佐藤和貴郎
- Journal Title
  
  日本多発性硬化症協会ニュース・レター No.32
  
  Pages: 1-4
- Data Source
  KAKENHI-PROJECT-20790632
[Patent] 多発性硬化症抑制剤2018
- Inventor(s)
  大木　伸司、山村　隆、佐藤和貴郎、ベン・レイバニー
- Industrial Property Rights Holder
  国立精神・神経医療センター
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Biomarkers for precision medicine of MS/NMO2021
- Author(s)
  Yamamura T, Raveney, B., Sato, W., and Oki, S
- Organizer
  20th Annual Congress. Israel Society of Neuroimmunology. Joint Meeting with the Japanese Society of Neuroimmunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Elucidation of Gut Microbial Species and Functions Associated with Secondary Progressive Multiple Sclerosis2021
- Author(s)
  Takewaki D, Sato W, Suda W, Miyake S, Hattori M, and Yamamura T
- Organizer
  ACTRIMS FORUM 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Development of blood biomarker using deviated B cell receptor repertoire in ME/CFS2021
- Author(s)
  Sato W, Yamamura T
- Organizer
  2021 IACFS/ME Virtual Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Alterations of the Gut Ecological and Functional Microenvironment in Different Stages of Multiple Sclerosis2020
- Author(s)
  Takewaki D, Sato W, Suda W, Takayasu L, Kumar N, Miyake S, Hattori M, and Yamamura T
- Organizer
  FOCIS 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Alterations of the gut ecological and functional microenvironment in different stages of MS2020
- Author(s)
  竹脇大貴, 佐藤和貴郎, 須田亙, 高安伶奈, Naveen Kumar, 三宅幸子, 服部正平, 山村隆
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Ecological and functional alterations of the gut microbiome in different stages of multiple sclerosis2020
- Author(s)
  Takewaki D, Suda W, Sato W, Takayasu L, Miyake S, Hattori M, and Yamamura T
- Organizer
  MS Virtual 2020; 8th Joint ACTRIMS-ECTRIMS Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] Increases in Eomes-expressing Th cells in secondary progressive multiple sclerosis reveal patients at risk of increased disability2018
- Author(s)
  Ben JE Raveney, Wakiro Sato, Daiki Takewaki, Youwei Lin, Tomoko Okamoto, Manabu Araki, Shinji Oki and Takashi Yamamura
- Organizer
  14th ISNI．Brisbane
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] ncreases in Eomes-expressing Th cells in secondary progressive multiple sclerosis reveal patients at risk of Increased disability2018
- Author(s)
  Ben Raveney, Wakiro Sato, Daiki Takewaki, Youwei Lin, Tomoko Okamoto, Manabu Araki, Shinji Oki, Takashi Yamamura
- Organizer
  FOCIS2018．San Francisco
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] 二次進行型多発性硬化症の病態とEomes陽性Th細胞2018
- Author(s)
  山村隆、佐藤和貴郎、大木伸司
- Organizer
  第36回日本神経治療学会学術集会．東京
- Data Source
  KAKENHI-PROJECT-18H04045
[Presentation] ケモカイン受容体の発説を用いた多発性硬化症患者におけるヒトTh17細胞の検討2009
- Author(s)
  佐藤和貴郎
- Organizer
  日本神経免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20790632
[Presentation] ケモカイン受容体の発現を用いた多発性硬化症患者におけるヒトTh17細胞の検討2009
- Author(s)
  佐藤和貴
- Organizer
  日本神経免疫学会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20790632
[Presentation] ケモカイン受容体の発現によって特徴づけられる二つのTh17細胞2008
- Author(s)
  佐藤和貴
- Organizer
  日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20790632
[Presentation] ケモカイン受容体の発現によって特徴づけられる二つのヒトTh17細胞2008
- Author(s)
  佐藤和貴郎
- Organizer
  日本免疫学会
- Place of Presentation
  大阪
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20790632
[Presentation] ヒトTh17細胞のケモカイン受容体の解析2008
- Author(s)
  佐藤和貴郎、荒浪利昌、山村隆
- Organizer
  日本神経免疫学会
- Place of Presentation
  新潟
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-20790632
[Presentation] Two different human Th17 cells defined by chemokine receptor expression2008
- Author(s)
  Wakiro Sato, Toshimasa Aranami and Takashi Yamamura
- Organizer
  Experimental Biology2008
- Place of Presentation
  米国サン・ディエゴ
- Year and Date
  2008-04-08
- Data Source
  KAKENHI-PROJECT-20790632
[Presentation] Two different human Th17 cells defined by chemokine receptor expression2008
- Author(s)
  Wakiro Sato, Toshimasa Aranami, Takashi Yamamura
- Organizer
  Experimental Biology2008
- Place of Presentation
  SanDiego
- Year and Date
  2008-04-08
- Data Source
  KAKENHI-PROJECT-20790632

1. Yamamura Takashi (90231670)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. 大木伸司 (50260328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. Nakane Shunya (70398022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 池田徳典 (00613530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 佐藤伸一 (20215792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 田村直人 (20227284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 樋口理 (50361720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 鈴木隆二 (70373470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 坪井洋人 (80580505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 伊原栄吉 (80612390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宋文杰 (90216573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 川上純 (90325639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 北條浩彦 (60238722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 林幼偉 (80392439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. 大島登志男 (20311334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 服部正平 (70175537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 土居芳充 (20597174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 須田亙 (20590847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 荒木敏之 (70263275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. TAKA Hikari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. KAGA Naoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. Raveney Benjamin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 堀昌平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sato Wakiro 佐藤 和貴郎

佐藤 和貴郎 サトウ ワキロウ

SATO Wakiro 佐藤 和貴郎

Research Projects

Research Products

Co-Researchers

Neuroinflammatory and degenerative pathogenesis mediated by new T cell subsets

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multidisciplinary analysis of heterogeneity in autoimmune autonomic ganglionopathy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cross-talk between endocrine and environmental factors in neuroimmune disorders

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Interaction between Th17 cells and B cells in the pathogenesis of multiple sclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Annual Review 神経2019 （鈴木則宏/荒木信夫/宇川義一/桑原 聡/塩川芳昭 編） 7.脱髄・免疫性疾患の1.腸内細菌叢と多発性硬化症2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] First-in-human clinical trial of the NKT cell-stimulatory glycolipid OCH in multiple sclerosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ratio of lymphocyte to monocyte area under the curve as a novel predictive factor for severe infection in multiple sclerosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuropilin-1 (NRP1) expression distinguishes self-reactive helper T cells in systemic autoimmune disease.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Involvement of cytotoxic Eomes-expressing CD4+ T cells in secondary progressive multiple sclerosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Th1-CD11c+ B cell axis associated with response to plasmapheresis in multiple sclerosis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Skewing of the B cell receptor repertoire in myaligic encephalomyelitis/chronic fatigue syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Alterations of the gut ecological and functional microenvironment in different stages of multiple sclerosis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gut microbiota-dependent CCR9+CD4+ T cells are altered in secondary progressive multiple sclerosis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiple sclerosis: Possibility of a gut environment-induced disease2019

Author(s)

Journal Title

DOI

Sato Wakiro 佐藤和貴郎

佐藤和貴郎サトウワキロウ

SATO Wakiro 佐藤和貴郎

[Book] Annual Review 神経2019 （鈴木則宏/荒木信夫/宇川義一/桑原　聡/塩川芳昭編） 7.脱髄・免疫性疾患の1.腸内細菌叢と多発性硬化症2019