EHATA SHOGO 江幡正悟

… Alternative Names

Ehata Shogo 江幡正悟

EHATA Shogo 江幡正悟

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Researcher Number	90506726
Other IDs
Affiliation (Current)	2025: 和歌山県立医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 和歌山県立医科大学, 医学部, 教授 2021 – 2022: 和歌山県立医科大学, 医学部, 教授 2019 – 2020: 東京大学, 環境安全研究センター, 准教授 2016 – 2017: 東京大学, 大学院医学系研究科(医学部), 特任准教授 2015: 東京大学, 医学(系)研究科(研究院), 講師 … More 2015: 東京大学, 大学院医学系研究科, 特任講師 2013: 東京大学, 医学(系)研究科(研究院), 講師 2012 – 2013: 東京大学, 医学(系)研究科(研究院), 助教 2008 – 2011: The University of Tokyo, 大学院・医学系研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Tumor biology / Experimental pathology Except Principal Investigator Complex systems / Biological Sciences / Biological Sciences
Keywords	Principal Investigator がん微小環境 / 腎がん / アポトーシス / 転移 / 脳転移 / 骨転移 / エピジェネティクス / 炎症性サイトカイン / スーパーエンハンサー / 好中球 … More / 薬剤感受性 / 癌微小環境 / 腎癌 / DNAメチル化 / 炎症 / エピゲノム / TGF-beta/BMP / Erk / 大腸癌 / DUSP5 / Erk MAPK / BMP-4 / Apoptosis / Colorectal cancer / 前立腺癌 / TGF-β / ALDH1 / ABCG2/BCRP / 癌幹細胞 / スキルス胃癌 / TGF-beta / 薬剤反応性 / 病理学 / シグナル伝達 / 癌 / 遺伝子 … More Except Principal Investigator シグナル伝達 / 発生・分化 / 血管新生 / 転移 / がん幹細胞 / TGF-β / 癌 / BMP / リンパ管新生 / がん浸潤 / 微小環境 / ゲノム科学 / 生体イメージング / 生体材料 / がん微小環境 / Smad7 / DDS / 乳がん / 膵臓がん / がん朝細胞 / 脳腫瘍 / 胃がん / シグナル伝逹 / 分子標的治療 Less

融合遺伝子TLS-CHOPを中心とした粘液型脂肪肉腫の転移メカニズムの解明Principal Investigator
- Principal Investigator
  
  江幡正悟
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Wakayama Medical University
微小環境に着目した腎癌骨転移の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  江幡正悟
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Wakayama Medical University
Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasisPrincipal Investigator
- Principal Investigator
  
  Ehata Shogo
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Wakayama Medical University
  The University of Tokyo
Molecular mechanisms of cell differentiation and diversity by TGF-beta family members
- Principal Investigator
  
  Miyazono Kohei
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
BMP-4 as a new therapeutic target in colorectal cancerPrincipal Investigator
- Principal Investigator
  
  Ehata Shogo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Molecular mechanism of prostate cancer metastasis to bonePrincipal Investigator
- Principal Investigator
  
  EHATA Shogo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Tumorigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-beta.Principal Investigator
- Principal Investigator
  
  EHATA Shogo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Effects of TGF-beta family on cancer microenvironment and strategies for cancer therapy
- Principal Investigator
  
  MIYAZONO Kohei
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
TGF-beta decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cellsPrincipal Investigator
- Principal Investigator
  
  EHATA Shogo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Establishment of New Strategies for Treatment of Cancer Using TGF-beta Signaling
- Principal Investigator
  
  MIYAZONO Kohei
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] 胃癌におけるTGF-betaシグナルの役割、別冊「医学のあゆみ」TGF-betaシグナル研究、メカニズムの解明から新たな治療へ2011
- Author(s)
  江幡正悟
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22700876
[Journal Article] An in vivo orthotopic serial passaging model for a metastatic renal cancer study2022
- Author(s)
  Jun Nishida, Kosuke Miyakuni, Kohei Miyazono, Shogo Ehata
- Journal Title
  
  STAR Protocols
  
  Volume: 3 Issue: 2 Pages: 101306-101306
- DOI
  10.1016/j.xpro.2022.101306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J12321, KAKENHI-PLANNED-17H06326
[Journal Article] An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis2022
- Author(s)
  Takahashi K, Abe K, Kubota SI, Fukatsu N, Morishita Y, Yoshimatsu Y, Satoshi Hirakawa, Yoshiaki Kubota, Tetsuro Watabe, Shogo Ehata, Hiroki R. Ueda, Teppei Shimamura, Kohei Miyazono
- Journal Title
  
  Nature Communiactions
  
  Volume: 13 Issue: 1 Pages: 5239-5239
- DOI
  10.1038/s41467-022-32848-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07094, KAKENHI-PROJECT-22K15435, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-20H03851, KAKENHI-PROJECT-20H04281, KAKENHI-PROJECT-20K21832, KAKENHI-PUBLICLY-22H04839, KAKENHI-PLANNED-17H06326, KAKENHI-ORGANIZER-19H05794, KAKENHI-PROJECT-20H00513
[Journal Article] Genome-wide analysis of DNA methylation identifies the apoptosis-related gene UQCRH as a tumor suppressor in renal cancer2022
- Author(s)
  Kosuke Miyakuni, Jun Nishida, Daizo Koinuma, Genta Nagae, Hiroyuki Aburatani, Kohei Miyazono, Shogo Ehata
- Journal Title
  
  Molecular Oncology
  
  Volume: 16 Issue: 3 Pages: 732-749
- DOI
  10.1002/1878-0261.13040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21J12321, KAKENHI-PROJECT-19K07684, KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-23K21431
[Journal Article] Bone Morphogenetic Protein Signaling in Cancer; Some Topics in the Recent 10 Years2022
- Author(s)
  Ehata Shogo、Miyazono Kohei
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 101306-101306
- DOI
  10.3389/fcell.2022.883523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07684, KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-20H00513
[Journal Article] Heterogenous expression of endoglin marks advanced renal cancer with distinct tumor microenvironment fitness.2021
- Author(s)
  Yusaku Momoi, Jun Nishida, Kosuke Miyakuni, Masafumi Kuroda, Shimpei I Kubota, Kohei Miyazono, Shogo Ehata
- Journal Title
  
  Cancer science
  
  Volume: 112 Issue: 8 Pages: 3136-3149
- DOI
  10.1111/cas.15007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16212, KAKENHI-PROJECT-21J12321, KAKENHI-PROJECT-19K07684, KAKENHI-PLANNED-17H06326
[Journal Article] Whole-organ analysis of TGF-β-mediated remodelling of the tumour microenvironment by tissue clearing.2021
- Author(s)
  Kubota SI, Takahashi K, Mano T, Matsumoto K, Katsumata T, Shi S, Tainaka K, Ueda HR, Ehata S, Miyazono K.
- Journal Title
  
  Commun. Biol.
  
  Volume: 4 Issue: 1 Pages: 294-294
- DOI
  10.1038/s42003-021-01786-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21246, KAKENHI-PROJECT-15H05774, KAKENHI-PLANNED-17H06326, KAKENHI-PUBLICLY-20H04700, KAKENHI-PROJECT-18H02105, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-19J13071, KAKENHI-PROJECT-20K16212, KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-19K16487, KAKENHI-PLANNED-20H05903
[Journal Article] Visualization of the cancer cell cycle by tissue-clearing technology using the Fucci reporter system.2021
- Author(s)
  Kei Takahashi, Ryo Tanabe, Shogo Ehata, Shimpei I Kubota, Yasuyuki Morishita, Hiroki R Ueda, Kohei Miyazono
- Journal Title
  
  Cancer science
  
  Volume: 112 Issue: 9 Pages: 3796-3809
- DOI
  10.1111/cas.15034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16212, KAKENHI-PROJECT-20H00513, KAKENHI-PLANNED-17H06326
[Journal Article] Neurotensin receptor 1 signaling promotes pancreatic cancer progression2020
- Author(s)
  Takahashi Kei、Ehata Shogo、Miyauchi Kensuke、Morishita Yasuyuki、Miyazawa Keiji、Miyazono Kohei
- Journal Title
  
  Molecular Oncology
  
  Volume: 15 Issue: 1 Pages: 151-166
- DOI
  10.1002/1878-0261.12815
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06326
[Journal Article] Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis2020
- Author(s)
  Nishida Jun、Momoi Yusaku、Miyakuni Kosuke、Tamura Yusuke、Takahashi Kei、Koinuma Daizo、Miyazono Kohei、Ehata Shogo
- Journal Title
  
  Nature Cell Biology
  
  Volume: 110 Issue: 4 Pages: 2063-2074
- DOI
  10.1038/s41556-020-0491-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07684, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06326
[Journal Article] Protocol for Imaging and Analysis of Mouse Tumor Models with CUBIC Tissue Clearing2020
- Author(s)
  Takahashi Kei, Kubota Shimpei I., Ehata Shogo, Ueda Hiroki R., Miyazono Kohei
- Journal Title
  
  STAR Protocols
  
  Volume: 1 Issue: 3 Pages: 100191-100191
- DOI
  10.1016/j.xpro.2020.100191
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05774, KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-18H05270, KAKENHI-PROJECT-19K16604, KAKENHI-PROJECT-20H00513
[Journal Article] c‐Ski accelerates renal cancer progression by attenuating transforming growth factor β signaling2019
- Author(s)
  Taguchi Luna、Miyakuni Kosuke、Morishita Yasuyuki、Morikawa Teppei、Fukayama Masashi、Miyazono Kohei、Ehata Shogo
- Journal Title
  
  Cancer Science
  
  Volume: 22 Issue: 6 Pages: 465-475
- DOI
  10.1111/cas.14018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07684, KAKENHI-PROJECT-15H05774
[Journal Article] Intracellular and extracellular TGF-β signaling in cancer: some recent topics.2018
- Author(s)
  Kohei Miyazono, Yoko Katsuno, Daizo Koinuma, Shogo Ehata, Masato Morikawa
- Journal Title
  
  Frontiers of Medicine
  
  Volume: 12 Issue: 4 Pages: 387-411
- DOI
  10.1007/s11684-018-0646-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-17H06324, KAKENHI-PROJECT-15H05774, KAKENHI-PLANNED-17H06326
[Journal Article] Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cells2018
- Author(s)
  Takahashi K, Ehata S, Koinuma D, Morishita Y, Soda M, Mano H, Miyazono K.
- Journal Title
  
  Oncogene
  
  Volume: - Issue: 21 Pages: 2757-2772
- DOI
  10.1038/s41388-018-0144-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06326, KAKENHI-PROJECT-15H05774
[Journal Article] Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer2017
- Author(s)
  Yokoyama Y, Watanabe T, Tamura Y, Hashizume Y, Miyazono K, Ehata S.
- Journal Title
  
  Cancer Research
  
  Volume: 77 Issue: 15 Pages: 4026-4038
- DOI
  10.1158/0008-5472.can-17-0112
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-15K08393
[Journal Article] Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution2017
- Author(s)
  Kubota Shimpei I.、Takahashi Kei、Nishida Jun、Morishita Yasuyuki、Ehata Shogo、Tainaka Kazuki、Miyazono Kohei、Ueda Hiroki R.
- Journal Title
  
  Cell Reports
  
  Volume: 20 Issue: 1 Pages: 236-250
- DOI
  10.1016/j.celrep.2017.06.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05688, KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-25221004, KAKENHI-PROJECT-16J05993, KAKENHI-PROJECT-17J30007, KAKENHI-PROJECT-15K08393, KAKENHI-PROJECT-16K15124
[Journal Article] Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program2016
- Author(s)
  Vasilaki E, Morikawa M, Koinuma D, Mizutani A, Hirano Y, Ehata S, Sundqvist A, Kawasaki N, Cedervall J, Olsson AK, Aburatani H, Moustakas A, Miyazono K, Heldin CH.
- Journal Title
  
  Sci Signal.
  
  Volume: 9 Issue: 442
- DOI
  10.1126/scisignal.aag3232
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05774, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-15K08393
[Journal Article] EZH2 promotes progression of small cell lung cancer by suppressing the TGF-β-Smad-ASCL1 pathway2015
- Author(s)
  Fumihiko Murai, Daizo Koinuma, Aya Shinozaki-Ushiku, Masashi Fukayama, Kohei Miyaozono, Shogo Ehata
- Journal Title
  
  Cell Discovery
  
  Volume: 1 Issue: 1 Pages: 15026-15026
- DOI
  10.1038/celldisc.2015.26
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08393, KAKENHI-PLANNED-22112002
[Journal Article] Smad4 Decreases the Population of Pancreatic Cancer-Initiating Cells through Transcriptional Repression of ALDH1A12015
- Author(s)
  Hoshino Y, Nishida J, Katsuno Y, Koinuma D, Aoki T, Kokudo N, Miyazono K, Ehata S.
- Journal Title
  
  American Journal of Pathology
  
  Volume: 印刷中 Issue: 5 Pages: 1457-1470
- DOI
  10.1016/j.ajpath.2015.01.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112002
[Journal Article] Bi-directional roles of bone morphogenetic proteins in cancer : another molecular Jekyll and Hyde?2013
- Author(s)
  Shogo Ehata, Yuichiro Yokoyama and Kei Takahashi, Kohei Miyazono
- Journal Title
  
  Pathology International
  
  Volume: 63 Issue: 6 Pages: 287-296
- DOI
  10.1111/pin.12067
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J10991, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24390070, KAKENHI-PROJECT-24700967
[Journal Article] TGF-β-inducedapoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20.2013
- Author(s)
  Kawabata KC, Ehata S, Komuro A, Takeuchi K, Miyazono K.
- Journal Title
  
  Oncogene
  
  Volume: 32(16) Issue: 16 Pages: 2096-106
- DOI
  10.1038/onc.2012.219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J09414, KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24700967
[Journal Article] Prostate cancer cells and bone stromal cells mutually interact with each other through bone morphogenetic protein-mediated signals2012
- Author(s)
  Nishimori H
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 24 Pages: 20037-20046
- DOI
  10.1074/jbc.m112.353094
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-24689018, KAKENHI-PROJECT-24700967, KAKENHI-PUBLICLY-23112702
[Journal Article] Tumor-promoting functions of transforming growth factor-β in progression of cancer2012
- Author(s)
  Miyazono K
- Journal Title
  
  Ups J Med Sci
  
  Volume: 117 Issue: 2 Pages: 143-152
- DOI
  10.3109/03009734.2011.638729
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22700876, KAKENHI-PROJECT-24700967
[Journal Article] Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β2012
- Author(s)
  Katsuno Y
- Journal Title
  
  J Pathol
  
  Volume: 228 Issue: 3 Pages: 391-404
- DOI
  10.1002/path.4020
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112002, KAKENHI-PROJECT-22700876, KAKENHI-PROJECT-23390329, KAKENHI-PROJECT-24700967
[Journal Article] Transforming growth factor-beta decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells2011
- Author(s)
  Ehata S、Johansson E、Katayama R、Koike S、Watanabe A、Hoshino Y、Katsuno Y、Komuro A、Koinuma D、Kano MR、Yashiro M、Hirakawa K、Aburatani H、Fujita N、Miyazono K
- Journal Title
  
  Oncogene
  
  Volume: Vol.30、No.14 Issue: 14 Pages: 1693-1705
- DOI
  10.1038/onc.2010.546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700876
[Journal Article] Transforming growth factor-beta decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells2011
- Author(s)
  江幡正悟
- Journal Title
  
  Oncogene
  
  Volume: (掲載確定(印刷中))
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700876
[Journal Article] Transforming growth factor-β decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cells2011
- Author(s)
  Ehata S, et al
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 783-795
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112002
[Journal Article] Bone morphogenetic protein-2/4 play tumor suppressive roles in human diffuse-type gastric carcinoma2011
- Author(s)
  Shirai YT、Ehata S、Yashiro M、Yanagihara K、Hirakawa K、Miyazono K
- Journal Title
  
  Amerian Journal of Pathology
  
  Volume: Vol.179、No.6 Pages: 2920-2930
- URL
  http://dx.doi.org/10.1016/j.ajpath.2011.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700876
[Journal Article] 胃癌におけるTGF-βシグナルの役割2010
- Author(s)
  江幡正悟
- Journal Title
  
  週刊医学のあゆみ
  
  Volume: 10号 Pages: 937-941
- Data Source
  KAKENHI-PROJECT-22700876
[Journal Article] Bone morphogenetic protein signaling enhances invasion and bone metastasis of breast cancer cells through Smad pathway.2008
- Author(s)
  Katsuno, Y., Hanyu, A., Kanda, H., Ishikawa, Y., Akiyama, F., Iwase, T., Ogata, E., Ehata, S., Miyazono, K., Imamura, T.
- Journal Title
  
  Oncogene 27(49)
  
  Pages: 6322-6333
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Transforming growth factor-βpromotes survival of mammary carcinoma cells through induction of anti-apoptotic transcription factor DEC1.2007
- Author(s)
  Ehata, S., Hanyu, A., Hayashi, M., Aburatani, H., Kato, Y., Fujime, M., Saitoh, M., Miyazawa, K., Imamura, T., Miyazono, K.
- Journal Title
  
  Cancer Res. 67(20)
  
  Pages: 9694-9703
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Transforming growth factor-β promotes survival of mammary carcino-ma cells through induction of anti-apoptotic transcription factor DEC12007
- Author(s)
  Ehata, S., et. al.
- Journal Title
  
  Cancer Research 67
  
  Pages: 9694-9703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Ki26894, a novel transforming growth factor-βtype I receptor kinase inhibitor, inhibits in vitro cell motility and invasion and in vivo bone metastasis of a human breast cancer cell line.2007
- Author(s)
  Ehata, S., Hanyu, A., Katsuno, Y., Fukunaga, E., Goto, K., Ishikawa, Y., Nomura, K., Ogata, E., Fujime, M., Miyazono, K., Shimizu, K., Imamura, T.
- Journal Title
  
  Cancer Sci. 98(1)
  
  Pages: 127-133
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Ki26894, a novel transforming growth factor-β type I receptor kinase inhibitor, inhibits in vitro cell motility and invasion and in vivo bone metastasis of a human breast cancer cell line.2007
- Author(s)
  Ehata, S., et al.
- Journal Title
  
  Cancer Sci. 98 (1)
  
  Pages: 127-133
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Nuclear and cytoplasmic c-Ski differentially modulate cellular functions.2006
- Author(s)
  Nagata, M., Goto, K., Ehata, S., Kobayashi, N., Saitoh, M., Miyoshi, H., Imamura, T., Miyazawa, K., Miyazono, K.
- Journal Title
  
  Genes Cells 11(11)
  
  Pages: 1267-1280
- Data Source
  KAKENHI-PROJECT-17016011
[Journal Article] Effect of Smad7 expression on metastasis of mouse mammary carcinoma JygMC(A) cells.2005
- Author(s)
  Azuma, H., Ehata, S., Miyazaki, H., Watabe, T., Maruyama, O., Imamura, T., Sakamoto, T., Kiyama, S., Kiyama, Y., Ubai, T., Inamoto, T., Takahara, S., Itoh, Y., Otsuki, Y., Katsuoka, Y., Miyazono, K., Horie, S.
- Journal Title
  
  J. Natl. Cancer Inst. 97(23)
  
  Pages: 1734-1746
- Data Source
  KAKENHI-PROJECT-17016011
[Patent] TGFβ阻害機能を持つキメラタンパク質2014
- Inventor(s)
  渡部徹郎、宮園浩平、鯉沼代造、江幡正悟、赤津裕一
- Industrial Property Rights Holder
  日本化薬株式会社、国立大学法人東京大学
- Industrial Property Rights Type
  特許
- Filing Date
  2014-08-11
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 卵巣がんにおける電子伝達系構成分子UQCRH 発現低下の機能解析2023
- Author(s)
  西川瑞希、中西雅子、松崎生笛、村田晋一、江幡正悟
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Genome-wide analysis of DNA methylation identifies molecular mechanism of anti-apoptotic ability in renal cancer cells2022
- Author(s)
  Kosuke Miyakuni, Jun Nishida, Daizo Koinuma, Shogo Ehata, Kohei Miyazono
- Organizer
  第21回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 腎細胞がんにおける脳転移の分子メカニズム解析2022
- Author(s)
  宮國昂介、西田純、荻窪一貴、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K07214
[Presentation] 淡明細胞型腎細胞癌におけるendoglin陽性細胞のがん幹細胞としての評価2021
- Author(s)
  桃井悠作、西田純、宮國昂介、江幡正悟、宮園浩平
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] DNA methylation enhances apoptosis resistance of renal cell carcinoma cells2021
- Author(s)
  宮國昂介、西田純、江幡正悟、宮園浩平
- Organizer
  第24回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Identification of genes and their regulatory mechanisms related to the metastasis of triple-negative breast cancer (Oral)2021
- Author(s)
  Ogikubo K, Tamura Y, Nishida J, Takahashi K, Morikawa M, Ehata S, Koinuma D, Miyazono K.
- Organizer
  第80回日本癌学会学術総会（横浜、hybrid）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Molecular mechanism of neutrophil-dependent metastasis of inflammatory renal cancer (Symposium)2021
- Author(s)
  Ehata S, Nishida J, Miyakuni K, Koinuma D, Miyazono K.
- Organizer
  第80回日本癌学会学術総会（横浜、hybrid）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 腎細胞がんはDNAメチル化を介してアポトーシス耐性を獲得する2021
- Author(s)
  宮國昂介、西田純、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 淡明細胞型腎細胞癌におけるendoglin陽性細胞のがん幹細胞としての評価（ワークショップ）2021
- Author(s)
  桃井悠作、西田純、宮國昂介、江幡正悟、宮園浩平
- Organizer
  第25回日本がん分子標的治療学会学術集会（online）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 腎細胞がんはDNAメチル化を介してアポトーシス耐性を獲得する（口演）2021
- Author(s)
  宮國昂介、西田純、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  第80回日本癌学会学術総会（横浜、hybrid）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 三次元病理解析に資する組織透明化手法の開発2021
- Author(s)
  久保田晋平、高橋恵生、田井中一貴、江幡正悟、上田泰己、宮園浩平
- Organizer
  第110回日本病理学会総会（東京、online）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Genome-wide analysis of DNA methylation identifies apoptosis-related gene UQCRH in renal cancer2021
- Author(s)
  江幡正悟、宮國昂介、西田純、宮園浩平
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 好中球を介した腎がん肺転移の分子メカニズムの解明と新たな治療の可能性2021
- Author(s)
  江幡正悟
- Organizer
  第49回和歌山腫瘍研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Molecular mechanism of neutrophil-dependent metastasis of inflammatory renal cancer2021
- Author(s)
  Ehata S, Nishida J, Miyakuni K, Koinuma D, Miyazono K.
- Organizer
  第80回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] トリプルネガティブ乳がんTNBCの高悪性化に伴うエピゲノム変化と治療標的遺伝子の同定（口演：優秀演題賞）2021
- Author(s)
  荻窪一貴、田村佑介、西田純、高橋恵生、江幡正悟、鯉沼代造、宮園浩平
- Organizer
  第25回日本がん分子標的治療学会学術集会（online）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Mitochondrial dysfunction in renal cancer progression2020
- Author(s)
  Shogo Ehata, Kosuke Miyakuni, Jun Nishida, Kohei Miyazono
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 腎がんの肺転移に対するBET阻害剤の有用性2020
- Author(s)
  江幡正悟、西田純、鯉沼代造、宮園浩平
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 腎がんは腎微小環境との相互作用を介してアポトーシス耐性を獲得する2020
- Author(s)
  宮國昂介、西田純、江幡正悟、宮園浩平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Whole-organ quantitative analysis of cancer metastasis with single cell resolution（Symposia: Single cell biology of cancer）2020
- Author(s)
  Kubota S, Takahashi K, Nishida J, Ehata S, Miyazono K.
- Organizer
  第79回日本癌学会学術総会（広島）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] BET inhibitor suppresses neutrophil-dependent lung metastasis of inflammatory renal cancer cells2020
- Author(s)
  Shogo Ehata, Jun Nishida, Kosuke Miyakuni, Daizo Koinuma, Kohei Miyazono
- Organizer
  AACR Virtual Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Analysis of tumor microenvironment with tissue-clearing technology （ワークショップ微小環境・血管新生・低酸素）2020
- Author(s)
  Takahashi K, Ehata S, Miyazono K.
- Organizer
  第24回日本がん分子標的治療学会学術集会（徳島）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Identification of key molecules in pancreatic cancer metastasis using a mouse orthotopic inoculation model （ワークショップ転移・浸潤）2020
- Author(s)
  Miyauchi K, Takahashi K, Ehata S, Miyazono K.
- Organizer
  第24回日本がん分子標的治療学会学術集会（徳島）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 腫瘍組織内ダイバーシティーの解析に資する全身全細胞解析技術の構築2020
- Author(s)
  久保田晋平、高橋恵生、西田純、江幡正悟、田井中一貴、上田泰己、宮園浩平
- Organizer
  新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第5回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Mechanisms of neutrophil-dependent metastasis of inflammatory renal cell caecinoma2020
- Author(s)
  Kohei Miyazono, Shogo Ehata, Jun Nishida, Kei Takahashi
- Organizer
  第79回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Mitochondrial dysfunction in renal cancer progression（Oral Sessions）2020
- Author(s)
  Ehata S, Miyakuni K, Nishida J, Miyazono K.
- Organizer
  第79回日本癌学会学術総会（広島）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] DNAメチル化を介した腎がん細胞のアポトーシス耐性獲得の分子機構2020
- Author(s)
  宮國昂介、西田純、江幡正悟、宮園浩平
- Organizer
  新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第5回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Mechanisms of neutrophi-dependent metastasis of inflammatory renal cell carcinoma （International Sessions: New therapeutic strategy for controlling metastasis and relapse in cancer）2020
- Author(s)
  Miyazono K, Ehata S, Nishida J, Takahashi K.
- Organizer
  第79回日本癌学会学術総会（広島）
- Invited
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] DNAメチル化を介した腎がん細胞のアポトーシス耐性獲得の分子機構2020
- Author(s)
  宮國昂介、西田純、江幡正悟、宮園浩平
- Organizer
  文部科学省　科学研究費補助金　新学術領域研究　細胞社会ダイバーシティーの統合的解明と制御　第5回公開シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] DNA methylation enhances apoptosis resistance of renal cancer cells through the control of mitochondria related gene expression2020
- Author(s)
  Kosuke Miyakuni, Jun Nishida, Shogo Ehata, Kohei Miyazono
- Organizer
  AACR Virtual Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Analysis of molecular mechanism of renal cancer progression using serial orthotopic transplantation model2019
- Author(s)
  Shogo Ehata, Kosuke Miyakuni, Jun Nishida, Kohei Miyazono
- Organizer
  FASEB “The TGF-beta Superfamily Conference: Signaling in Development and Disease”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 腎細胞がんのエンハンサーリモデリングは好中球を介した肺転移機構を誘導する2019
- Author(s)
  西田純、高橋恵生、江幡正悟、宮園浩平
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 膵微小環境によるがん細胞の悪性形質の獲得機構2019
- Author(s)
  高橋恵生、江幡正悟、宮園浩平
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] マウス移植モデルを用いた膵がん新規標的分子の探索2019
- Author(s)
  高橋恵生、江幡正悟、宮園浩平
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Renal cancer cells acquire additional anti-apoptotic ability through the interactions with renal microenvironment2019
- Author(s)
  Miyakuni K, Nishida J, Ehata S, Miyazono K.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 微小環境との相互作用を介した腎がん細胞のアポトーシス耐性獲得2019
- Author(s)
  宮國昂介、西田純、江幡正悟、宮園浩平
- Organizer
  文部科学省　科学研究費補助金　新学術領域研究　細胞社会ダイバーシティーの統合的解明と制御　第4回公開シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 腎細胞がんの好中球を介した肺転移機構に対するBET阻害剤の効果の検討2019
- Author(s)
  西田純、高橋恵生、江幡正悟、宮園浩平
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 腎細胞がんの好中球を介した肺転移機構に対するBET阻害剤の効果の検討2019
- Author(s)
  西田純、高橋恵生、江幡正悟、宮園浩平
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 腎細胞がんのエンハンサーリモデリングは好中球を介した肺転移機構を誘導する2019
- Author(s)
  西田純、高橋恵生、江幡正悟、宮園浩平
- Organizer
  第28回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 同所性移植を応用した腎癌の進展の分子メカニズムの解析2019
- Author(s)
  江幡正悟、宮國昂介、西田純、宮園浩平
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Analyses of cancer metastasis regulated by tumor microenvironments using orthotopic transplantation models2019
- Author(s)
  Miyazono K, Takahashi K, Kubota SI, Miyakuni K, Nishida J, Ehata S.
- Organizer
  第78回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] BET阻害剤の炎症を標的とした腎がん転移抑制効果2019
- Author(s)
  西田純、田村佑介、高橋恵生、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] 微小環境との相互作用を介した腎がん細胞のアポトーシス耐性獲得2019
- Author(s)
  宮國昂介、西田純、江幡正悟、宮園浩平
- Organizer
  新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第4回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] BET阻害剤の炎症を標的とした腎がん転移抑制効果2019
- Author(s)
  西田純、桃井悠作、田村佑介、高橋恵生、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  文部科学省　科学研究費補助金　新学術領域研究　細胞社会ダイバーシティーの統合的解明と制御　第4回公開シンポジウム
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] BET阻害剤の炎症を標的とした腎がん転移抑制効果2019
- Author(s)
  西田純、桃井悠作、田村佑介、高橋恵生、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  新学術領域研究「細胞社会ダイバーシティーの統合的解明と制御」第4回公開シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Analysis of molecular mechanism of renal cancer progression using serial orthotopic transplantation model2019
- Author(s)
  Miyakuni K, Nishida J, Ehata S, Miyazono K.
- Organizer
  Elventh AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 微小環境との相互作用を介した腎がん細胞のアポトーシス耐性獲得2019
- Author(s)
  江幡正悟、宮國昂介、西田純、宮園浩平
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K07684
[Presentation] Targeting metastasis-associated inflammation in renal cancer by BET inhibitor2019
- Author(s)
  Nishida J, Tamura Y, Takahashi K, Koinuma D, Ehata S, Miyazono K.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] Epigenetic remodeling of renal cancer cells in primary tumor microenvironment triggers neutrophil-dependent lung metastasis2018
- Author(s)
  Nishida J, Tamura Y, Takahashi K, Koinuma D, Ehata S, Miyazono K.
- Organizer
  第18回東京大学生命科学シンポジウム
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] 好中球依存的な腎細胞がん細胞肺転移機構を説明するエピゲノムの探索2018
- Author(s)
  西田純、高橋恵生、江幡正悟、宮園浩平
- Organizer
  第27回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] BMP阻害剤を応用した大腸がんの分子標的治療2017
- Author(s)
  江幡正悟、横山雄一郎、宮園浩平
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Whole-body/organ profiling of cancer metastasis with CUBIC-Cancer analysis2017
- Author(s)
  Shimpei I Kubota, Kei Takahashi, Jun Nishida, Shogo Ehata, Kazuki Tainaka, Ueda R. Hiroki, Kohei Miyazono
- Organizer
  2017年度生命科学系学会合同年次大会（第４０回日本分子生物学会年会、第９０回日本生化学会大会）（神戸）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] がん微小環境との相互作用により悪性化した腎細胞がん細胞は好中球の動態変化を誘発して肺転移を促進する2017
- Author(s)
  西田純、高橋恵生、江幡正悟、宮園浩平
- Organizer
  2017年度生命科学系学会合同年次大会（第４０回日本分子生物学会年会、第９０回日本生化学会大会）（神戸）
- Data Source
  KAKENHI-PLANNED-17H06326
[Presentation] BMP阻害剤を使用した大腸癌治療の試み2017
- Author(s)
  江幡正悟、横山雄一郎、渡邉聡明、田村佑介、宮園浩平
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Autocrine bone morphogenetic protein 4 signaling in colorectal cancer as a target for treatment.2017
- Author(s)
  Ehata S, Yokoyama Y, Watanabe T, Tamura Y, Hashizume Y, Miyazono K.
- Organizer
  FASEB “The TGF-beta Superfamily: Signaling in Development and Disease”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Autocrine BMP-4 accelerates proteasomal degradation of Bim and protects colorectal cancer cells from apoptosis2016
- Author(s)
  Yuichiro Yokoyama, Shogo Ehata, Toshiaki Watanabe, Kohei Miyazono
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Autocrine BMP-4 is a novel therapeutic target for colorectal cancer2016
- Author(s)
  Yuichiro Yokoyama, Shogo Ehata, Yasuyuki Morishita, Toshiaki Watanabe, Kohei Miyazono
- Organizer
  第10回日米癌合同会議
- Place of Presentation
  Maui, United States of America
- Year and Date
  2016-02-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Analysis of pancreatic microenvironment with an orthotopic injection model and in vivo bioluminescence imagine system2015
- Author(s)
  Ehata S, Takahashi K, Koinuma D, Miyazono K.
- Organizer
  日本癌学会シンポジウム／共同利用・共同研究拠点シンポジウム : がん幹細胞・微小環境・分子標的～がん進展制御への挑戦
- Place of Presentation
  石川県立音楽堂交流ホール（石川県・金沢市）
- Year and Date
  2015-01-21
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 大腸癌細胞はBMP-4を自己分泌しBimタンパクの分解を促進することでアポトーシスを抑制する2015
- Author(s)
  横山雄一郎、江幡正悟、宮園浩平
- Organizer
  第19回日本がん分子標的治療学会学術集会
- Place of Presentation
  松山全日空ホテル（愛媛県松山市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Autocrine BMP-4 accelerates proteasomal degradation of Bim and protects colorectal cancer cells from apoptosis2015
- Author(s)
  Yuichiro Yokoyama, Shogo Ehata, Toshiaki Watanabe, Kohei Miyazono
- Organizer
  第74回日本癌学会総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] Autocrine BMP-4 protects colorectal cancer cells from apoptosis through down-regulation of Bim2015
- Author(s)
  横山雄一郎、江幡正悟、渡邉聡明、宮園浩平
- Organizer
  平成27年度がん若手研究者ワークショップ
- Place of Presentation
  蓼科グランドホテル滝の湯（長野県茅野市）
- Year and Date
  2015-09-03
- Data Source
  KAKENHI-PROJECT-15K08393
[Presentation] 小細胞肺がんにおけるTGF-βシグナルの機能解析（ワークショップ）2014
- Author(s)
  村井文彦、江幡正悟、宮園浩平
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ（宮城県・仙台市）
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] Regulation of EMT and related phenotypes by TGF-β in cancer cells (Symposium)2014
- Author(s)
  Koinuma D, Isogaya K, Sakurai T, Kawasaki N, Ehata S, Tsutsumi S, Saito A, Miyazawa K, Aburatani H, Miyazono K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] Autocrine BMP-4 protects colorectal cancer cells from apoptosis through down-regulation of Bim (English Oral Session)2014
- Author(s)
  Yokoyama Y, Ehata S, Miyazono K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 肺線癌におけるTGF-β標的遺伝子RBM47の発現と作用機構の解析2014
- Author(s)
  櫻井翼、鯉沼代造、磯谷一暢、坂井慧、森川真大、森下保幸、江幡正悟、宮園浩平
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2014-10-15
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] Emerging regulatory mechanism of mTOR signaling by a novel TGF-β target gene (English Oral Session)2014
- Author(s)
  Kawasaki N, Isogaya K, Koinuma D, Ehata S, Miyazono K.
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 腎癌幹細胞における TGF-β の機能解析2014
- Author(s)
  西田純、江幡正悟、宮園浩平
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 小細胞肺癌の進展におけるTGF-βの機能解析2014
- Author(s)
  江幡正悟、村井文彦、宮園浩平
- Organizer
  第103回日本病理学会総会
- Place of Presentation
  広島国際会議場（広島県・広島市）
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 小細胞肺がんにおける TGF-β シグナルの機能解析2014
- Author(s)
  村井文彦、江幡正悟、鯉沼代造、牛久綾、深山正久、宮園浩平
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 肺線癌におけるTGF-β標的遺伝子RBM47の発現と作用機構の解析2014
- Author(s)
  櫻井翼、鯉沼代造、江幡正悟、宮園浩平
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ（宮城県・仙台市）
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 大腸癌細胞はBMP-4を自己分泌し、アポトーシスを抑制する2014
- Author(s)
  横山雄一郎、江幡正悟、宮園浩平
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  仙台市情報・産業プラザ（宮城県・仙台市）
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] 大腸癌におけるBMP-4の機能解析2014
- Author(s)
  江幡正悟、横山雄一郎、宮園浩平
- Organizer
  第21回BMP研究会
- Place of Presentation
  大阪大学中之島センター（大阪府・大阪市）
- Year and Date
  2014-07-27
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] Prostate cancer cells and bone stromal cells mutually interact with each other through BMP-mediated signals2013
- Author(s)
  Shogo Ehata、Hikaru Nishimori、Hiroshi Suzuki、Yoko Katsuno、Kohei Miyazono
- Place of Presentation
  アメリカ合衆国ハワイ州ハイアットリージェンシー
- Year and Date
  2013-02-22
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] Prostate cancer cells and bone stromal cells mutually interact with each other through BMP-mediated signals2012
- Author(s)
  Shogo Ehata、Hikaru Nishimori、Hiroshi Suzuki、Yoko Katsuno、Kohei Miyazono
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  北海道札幌市ホテルロイトン札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] The role of TGF-beta/BMP signaling in cancer progression2012
- Author(s)
  Shogo Ehata、Yoko Katsuno、Yukari Hoshino、Aki Hanyu、Haruhito Azuma、Takeshi Imamura、Kohei Miyazono
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  北海道札幌市ホテルロイトン札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] 前立腺癌細胞と骨間質細胞の相互作用におけるBMPの機能解析2012
- Author(s)
  江幡正悟、西森光、宮園浩平
- Organizer
  第19回BMP研究会
- Place of Presentation
  東京都新宿区慶應義塾大学
- Year and Date
  2012-07-22
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] 前立腺癌細胞と骨間質細胞の相互作用におけるBMPの機能解析2012
- Author(s)
  江幡正悟、西森光、宮園浩平
- Organizer
  第16回日本がん分子標的治療学会学術集会
- Place of Presentation
  福岡県北九州市西日本総合展示場
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] TGF-beta diminishes the Side Population fraction of the diffuse-type gastric cancer cells2011
- Author(s)
  Shogo Ehata、Erik Johansson、Ryohei Katayama、Sumie Koike、Akira Watanabe、Yukari Hoshino、Yoko Katsuno、Akiyoshi Komuro、Daizo Koinuma、Mitsunobu R. Kano、Masakazu Yashiro、Kosei Hirakawa、Hiroyuki Aburatani、Naoya Fujita、Kohei Miyazono
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] Cancer-initiating cell population in diffuse-type gastric carcinoma cells has high ALDH1 activity2011
- Author(s)
  Yoko Katsuno、Shogo Ehata、Masakazu Yashiro、Kazuyoshi Yanagihara、Kosei Hirakawa、Kohei Miyazono
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  愛知県名古屋市名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] Bone morphogenetic protin-2/4 play tumor suppressive roles in human diffuse-type gastric carcinoma2011
- Author(s)
  Yo-taro Shirai、Shogo Ehata、Masakazu Yashiro、Kosei Hirakawa、Kohei Miyazono
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  愛知県名古屋市名古屋国際会議場
- Year and Date
  2011-10-05
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] TGF-beta diminishes the SP fraction of the diffuse-type gastric carcinoma cells2010
- Author(s)
  Shogo Ehata、Ryohei Katayama、Sumie Koike、Yukari Hoshino、Yoko Katsuno、Daizo Koinuma、Mitsunobu Kano、Masakazu Yashiro、Kosei Hirakawa、Naoya Fujita、Kohei Miyazono
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] Cancer-initiating cell population in diffuse-type gastric carcinoma cells has high ALDH1 activity2010
- Author(s)
  Yoko Katsuno、Shogo Ehata、Masakazu Yashiro、Kosei Hirakawa、Kohei Miyazono
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] BMP plays a tumor suppressive role in diffuse-type gastric carcinoma development2010
- Author(s)
  Yo-Taro Shirai、Shogo Ehata、Masakazu Yashiro、Kosei Hirakawa、Kohei Miyazono
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪府大阪市大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] TGF-beta diminishes the SP fraction of the diffuse-type gastric carcinoma cells.2010
- Author(s)
  江幡正悟
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  リーガロイヤルホテル大阪(大阪府大阪市)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22700876
[Presentation] TGF-β diminishes the SP fraction of the diffuse-type gastric cancer cells.2009
- Author(s)
  江幡正悟
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20890049
[Presentation] TGF-β diminishes the SP fraction of the diffuse-type gastric cancer cells2009
- Author(s)
  Shogo Ehata, Ryohei Katayama, Sumie Koike, Yukari Hoshino, Yoko Katsuno, Mitsunobu Kano, Masakazu Yashiro, Kosei Hirakawa, Hiroyuki Aburatani, Naoya Fujita, Kohei Miyazono
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20890049
[Presentation] TGF-β promotes survival of mammary carcinoma cells through induction of antiapoptotic transcription factor DEC12008
- Author(s)
  Ehata S, et al.
- Organizer
  TGF-β Meeting in Leiden
- Place of Presentation
  Leiden, Netherlands(ライデン大学医学センター)
- Data Source
  KAKENHI-PROJECT-17016011
[Presentation] Prostate cancer cells and bone stromal cells mutually interact with each other through BMP-mediated signals.
- Author(s)
  Shogo Ehata, Hikaru Nishimori, Hiroshi Suzuki, Yoko Katsuno, Kohei Miyazono
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  北海道（ロイトン札幌）
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] TGF-βは小細胞肺がんの進展を抑制する
- Author(s)
  村井文彦、江幡正悟、宮園浩平
- Organizer
  第17回日本がん分子標的治療学会学術集会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2013-06-12 – 2013-06-14
- Data Source
  KAKENHI-PLANNED-22112002
[Presentation] Prostate cancer cells and bone stromal cells mutually interact with each other through BMP-mediated signals.
- Author(s)
  Shogo Ehata, Hikaru Nishimori, Hiroshi I. Suzuki, Kohei Miyazono
- Organizer
  第9回日米癌合同会議
- Place of Presentation
  米国ハワイ州マウイ島（ハイアットリージェンシー）
- Data Source
  KAKENHI-PROJECT-24700967
[Presentation] 前立腺癌細胞と骨間質細胞の相互作用におけるBMPの機能解析
- Author(s)
  江幡正悟、西森光、宮園浩平
- Organizer
  第19回BMP研究会
- Place of Presentation
  東京都（慶應義塾大学）
- Data Source
  KAKENHI-PROJECT-24700967
[]
[]

1. MIYAZONO Kohei (90209908)

# of Collaborated Projects: 3 results

# of Collaborated Products: 53 results
2. KOINUMA Daizo (80375071)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. WATABE Tetsuro (00334235)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MIYAZAWA Keiji (40209896)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. IMAMURA Takeshi (70264421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. MAEDA Shingo (60353463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SAITOH Masao (90345041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KANO Mitsunobu (80447383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. JO Jun-ichiro (60511243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 森川真大 (80775833)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. Yokoyama Yuichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
13. 久保田晋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 田井中一貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 吉松康裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

EHATA SHOGO 江幡 正悟

Ehata Shogo 江幡 正悟

EHATA Shogo 江幡 正悟

Research Projects

Research Products

Co-Researchers

融合遺伝子TLS-CHOPを中心とした粘液型脂肪肉腫の転移メカニズムの解明Principal Investigator

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微小環境に着目した腎癌骨転移の分子メカニズムの解明Principal Investigator

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Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasisPrincipal Investigator

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Molecular mechanisms of cell differentiation and diversity by TGF-beta family members

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BMP-4 as a new therapeutic target in colorectal cancerPrincipal Investigator

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Molecular mechanism of prostate cancer metastasis to bonePrincipal Investigator

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Tumorigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-beta.Principal Investigator

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Effects of TGF-beta family on cancer microenvironment and strategies for cancer therapy

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TGF-beta decreases the cancer-initiating cell population within diffuse-type gastric carcinoma cellsPrincipal Investigator

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Establishment of New Strategies for Treatment of Cancer Using TGF-beta Signaling

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[Book] 胃癌におけるTGF-betaシグナルの役割、別冊「医学のあゆみ」TGF-betaシグナル研究、メカニズムの解明から新たな治療へ2011

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[Journal Article] An in vivo orthotopic serial passaging model for a metastatic renal cancer study2022

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[Journal Article] An analysis modality for vascular structures combining tissue-clearing technology and topological data analysis2022

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EHATA SHOGO 江幡正悟

Ehata Shogo 江幡正悟

EHATA Shogo 江幡正悟