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NAGAI Yasuhiro  永井 康裕

ORCIDConnect your ORCID iD *help
Researcher Number 90508962
Affiliation (based on the past Project Information) *help 2011: Tohoku University, 歯学研究科(研究院), 助教
2008 – 2010: Tohoku University, 大学院・歯学研究科, 助教
2009: 東北大, 歯学研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Morphological basic dentistry
Except Principal Investigator
Surgical dentistry
Keywords
Principal Investigator
免疫不応答 / 免疫寛容 / 食事性肥満 / 金属アレルギー / 舌下免疫 / アレルギー / 肥満 / 免疫 / B7-H3 / 制御性T細胞 / 共刺激分子 / 間葉系幹細胞 … More
Except Principal Investigator
… More 薬物副作用 / 壊死 / 炎症 / 骨吸収抑制薬 / 顎骨壊死 / ビスフォスフォネート Less
  • Research Projects

    (4 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (3 People)
  •  舌下免疫療法を利用した腸管炎症疾患への治療法の開発Principal Investigator

    • Principal Investigator
      永井 康裕
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Bisphosphonate-induced jawbone necrosis : studies for its mechanism, prevention, and treatment

    • Principal Investigator
      ENDO Yasuo
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tohoku University
  •  Effect of diet-induced obesity and its immuno-defect on sublingual immunotherapy.Principal Investigator

    • Principal Investigator
      NAGAI Yasuhiro
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  口腔粘膜の間葉系幹細胞が制御する免疫抑制機構の解明Principal Investigator

    • Principal Investigator
      永井 康裕
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University

All 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.2010

    • Author(s)
      Yosuke Shikama, Yasuhiro Nagai , Satoru Okada, Takefumi Oizum i, Hidetoshi Shimauchi, Shunji Sugawara, Yasuo Endo.
    • Journal Title

      Toxicology Letters

      Volume: 199 Pages: 123-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Journal Article] Pro-IL-1β accumulation in macrophages by alendronate and its prevention by clodronate.2010

    • Author(s)
      Shikama Y, Nagai Y, Okada S1, Oizumi T, Shimauchi H, Sugawara S, Endo Y.
    • Journal Title

      Toxicol Lett 199(2)

      Pages: 123-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Journal Article] Pro-IL-1ss accumulation in macrophages by alendronate and its prevention by clodronate2010

    • Author(s)
      Yosuke Shikama, Yasuhiro Nagai, Satoru Okada, Takefumi Oizumi, Hidetoshi Shimauchi, Shunji Sugawara, Yasuo Endo
    • Journal Title

      Toxicol Lett

      Volume: 199 Pages: 123-128

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Journal Article] Muramyldipeptide augments the actions of lipopolysaccharide in mice by stimulating macrophages to produce pro-IL-1 and by down-regulation of the suppressor of cytokine signaling 1 (SOCS1).2009

    • Author(s)
      Shikama Y, Kuroishi T, Nagai Y, Iwakura Y, Shimauchi H, Takada T, Sugawara S, Endo Y.
    • Journal Title

      Innate Immunity 17(1)

      Pages: 3-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Journal Article] Biotin status affects nickel allergy via regulation of interleukin-1beta production in mice.2009

    • Author(s)
      Kuroishi T, Kinbara M, Sato N, Tanaka Y, Nagai Y, Iwakura Y, Endo Y, Sugawara S.
    • Journal Title

      Journal of Nutrition 139

      Pages: 1031-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Journal Article] Biotin status affects nickel allergy via regulation of interleukin-1beta production in mice2009

    • Author(s)
      Kuroishi T, Kinbara M, Sato N, Tanaka Y, Nagai Y, Iwakura Y, Endo Y, Sugawara S.
    • Journal Title

      Journal of Nutrition 139

      Pages: 1031-1036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Journal Article] Anterior Pituitary Progenitor Cells Express Costimulatory Molecule 4Ig-B7-H32008

    • Author(s)
      Nagai Y., Aso H., Ogasawara H., Tanaka S., Taketa Y., Watanabe K., Ohwada S., Rose M. T., Kitazawa H., Yamaguchi T
    • Journal Title

      Journal of immunology 181

      Pages: 6073-6081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890020
  • [Journal Article] Anterior pituitary progenitor cells that express IL-18 and IL-18Rs serve as immuno-endocrine modulators2008

    • Author(s)
      Nagai Y., Ogasawara H., Taketa Y., Aso H., Tanaka S., Kanaya T., Watanabe K., Ohwada S., Muneta Y., Yamaguchi T
    • Journal Title

      Journal of Neuroendocrinology 20

      Pages: 1233-1241

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20890020
  • [Presentation] 骨吸収抑制作用とは関連しないbisphosphonates(BPs)の鎮痛作用.2010

    • Author(s)
      金始瑛, 永井康裕, 山本照子, 菅原俊二, 遠藤康男.
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Presentation] Histamine Reduces Susceptibility to NK Cells via Down-Regulation of NKG2D Ligand Expression on Human Monocytic Leukemia THP-1 Cells.2010

    • Author(s)
      Nagai Y., Tanaka Y., Kuroishi T., Sato R., Endo Y., Sugawara S.
    • Organizer
      8th joint conference of the ICS and ISICR
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Histamine Reduces Susceptibility to NK Cells via Down-Regulation of NKG2D Ligand Expression on Human Monocytic Leukemia THP-1 Cells2010

    • Author(s)
      Nagai Y., Tanaka Y., Kuroishi T., Sato R., Endo Y., Sugawara S
    • Organizer
      8^<th> joint conference of the ICS and ISICR
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2010-10-05
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Bisphosphonates(BPs)の炎症・壊死作用:マウス耳介皮膚での検討.2010

    • Author(s)
      岡田諭, 大泉丈史, 山口晃史, 永井康裕, 菅原俊二, 遠藤康男.
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Presentation] Analysis of antigen incorporating and processing cells in sublingal immunotherapy2010

    • Author(s)
      Shiraishi D., Nagai Y., Tanaka Y., Endo Y., Shimauchi H., Sugawara S
    • Organizer
      第39回日本免疫学会総会
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2010-10-04
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Histamine Reduces Susceptibility to NK Cells via Down-Regulation of NKG2D Ligand Expression on Human Monocytic Leukemia THP-1 Cells.2010

    • Author(s)
      Nagai Y., Tanaka Y., Endo Y., Sugawara S.
    • Organizer
      14th International Congress of Immunology.
    • Place of Presentation
      神戸
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] マクロファージにおけるAlendronateによるpro-IL-1b産生誘導とそのclodronateによる抑制2010

    • Author(s)
      四釜洋介, 永井康裕, 岡田諭, 大泉丈史, 島内英俊, 菅原俊二, 遠藤康男
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Presentation] 骨吸収抑制作用とは関連しないbisphosphonates(BPs)の鎮痛作用2010

    • Author(s)
      金始瑛, 永井康裕, 山本照子, 菅原俊二, 遠藤康男
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Presentation] マウスNiアレルギーにおける免疫記憶型CD3+NK1.1+細胞の関与2010

    • Author(s)
      永井康裕、金原正敬、田中志典、遠藤康男、菅原俊二
    • Organizer
      第52回歯科基礎医学会
    • Place of Presentation
      東京
    • Year and Date
      2010-09-09
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Bisphosphonates(BPs)の炎症・壊死作用:マウス耳介皮膚での検討2010

    • Author(s)
      岡田諭, 大泉丈史, 山口晃史, 永井康裕, 菅原俊二, 遠藤康男
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Presentation] マクロファーシにおけるAlendronateによるpro-IL-1β産生誘導とそのclodronateによる抑制.2010

    • Author(s)
      四釜洋介, 永井康裕, 岡田諭, 大泉丈史, 島内英俊, 菅原俊二, 遠藤康男.
    • Organizer
      歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21390529
  • [Presentation] Analysis of antigen incorporating and processing cells in sublingal immunotherapy.2010

    • Author(s)
      Shiraishi D., Nagai Y., Tanaka Y., Endo Y., Shimauchi H., Sugawara S.
    • Organizer
      8th joint conference of the ICS and ISICR
    • Place of Presentation
      Chicago, USA
    • Year and Date
      2010-10-04
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Histamine Reduces Susceptibility to NK Cells via Down-Regulation of NKG2D Ligand Expression on Human Monocytic Leukemia THP-1 Cells2010

    • Author(s)
      Nagai Y., Tanaka Y., Endo Y., Sugawara S
    • Organizer
      14^<th> International Congress of Immunology
    • Place of Presentation
      神戸
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Analysis of antigen incorporating and processing cells in sublingal immunotherapy2009

    • Author(s)
      Shiraishi D., Nagai Y., Tanaka Y., Endo Y., Shimauchi H., Sugawara S.
    • Organizer
      第39回日本免疫学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] ヒト歯肉由来間葉系幹細胞が発現するB7-H3分子による制御性T細胞誘導とその機能解析2009

    • Author(s)
      永井康裕、黒石智誠、白石大祐、大木亜紀子、島内英俊、菅原俊二
    • Organizer
      第51回歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Induction of Treg from PBMC by interacting with immunosuppressive B7-H3 molecule on oral mesenchymal stem cells from human gingival fibroblasts.2009

    • Author(s)
      Nagai Y., Shiraishi D., Ohki A., Tanaka Y., Aso H., Sugawara S.
    • Organizer
      第39回日本免疫学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Analysis of antigen incorporating and processing cells in subling al immunotherapy2009

    • Author(s)
      Shiraishi D., Nagai Y., Tanaka Y., Endo Y., Shimauchi H., Sugawara S
    • Organizer
      第39回日本免疫学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] 舌下粘膜の抗原取り込み機構と舌下粘膜免疫療法2009

    • Author(s)
      白石大祐、永井康裕、遠藤康男、島内英俊、菅原俊二
    • Organizer
      第51回歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21791781
  • [Presentation] Induction of Treg from PBMC by interacting with immunosuppressive molecules B7-H3 on oral mesenchymal stem cells from human ginaival fibroblasts2009

    • Author(s)
      Nagai Y, Kuroishi T, Ohki A, Sugawara S
    • Organizer
      Interface Oral Health Science
    • Place of Presentation
      仙台
    • Year and Date
      2009-01-15
    • Data Source
      KAKENHI-PROJECT-20890020
  • [Presentation] ヒト歯肉線維芽細胞からの間葉系幹細胞の樹立と共刺激分子の発現解析2009

    • Author(s)
      永井康裕、黒石智誠、白石大祐、大木亜紀子、菅原俊二
    • Organizer
      第50回歯科基礎医学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-23
    • Data Source
      KAKENHI-PROJECT-20890020
  • [Presentation] Induction of Treg from PBMC by interacting with immunosuppressive molecules on oral mesenchvmal stem cells from human gingival fibroblasts2008

    • Author(s)
      Nagai Y, Kuroishi T, Ohki A, Sugawara S
    • Organizer
      日本免疫学会学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-01
    • Data Source
      KAKENHI-PROJECT-20890020
  • [Presentation] Induction of Treg from PBMC by interacting with immunosuppressive molecules on oral mesenchvmal stem cells from human gingival fibroblasts2008

    • Author(s)
      Nagai Y, Kuroishi T, Ohki A, Sugawara S
    • Organizer
      The American society for cell biology 48^<th> annual meetig
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2008-12-16
    • Data Source
      KAKENHI-PROJECT-20890020
  • 1.  ENDO Yasuo (50005039)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  YAMAGUCHI Kouji (10372319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  横山 政宣 (20396500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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