KANEKO Tsuyoshi 金子剛

Researcher Number	90510181
Affiliation (based on the past Project Information) *help	2011 – 2014: 筑波大学, 医学医療系, 講師 2008 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 講師
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Radiation science / Gastroenterology
Keywords	Principal Investigator 細胞膜流動性 / 光学的生検 / 蛍光偏光解消法 / 悪性腫瘍 / 大腸癌 / アベラントクリプト / アゾキシメタン誘発大腸腺腫 / RGM-1細胞 / 消化器内視鏡 / 膜流動性 … More Except Principal Investigator … More ポルフィリン / 62Zn / がん画像診断 / PET / 陽電子放出型同位体 / 亜鉛ポルフィリン / 放射線腫瘍学 / スクリーニン / がんスクリーニング / 蛍光内視鏡 / 尿中ポルフィリン / がん固有蛍光 / 尿ポルフィリン類 / アミノレブリン酸 / 胃がん Less

An Optical Cancer Diagnosis with Fluorescence Polarization.Principal Investigator
- Principal Investigator
  
  KANEKO TSUYOSHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
A new tracer development for positron emission tomographic imaging with an isotope62Zn containing porphyrins
- Principal Investigator
  
  MATSUI Hirofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  University of Tsukuba
A screening test using urinal porphyrins for gastric cancer patients.
- Principal Investigator
  
  MATSUI Hirofumu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba
The Possibility of Cancer Diagnosis with Fluidity Sensitive Fluorescence MeasurementPrincipal Investigator
- Principal Investigator
  
  KANEKO Tsuyoshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Gastroenterology
- Research Institution
  University of Tsukuba

All 2015 2014 2013 2012 2010 2009 2008 Other

All Journal Article Presentation Patent

[Journal Article] 超高齢社会におけるレーザー治療の意義高齢者に対する消化器領域の光線力学療法2015
- Author(s)
  金子剛, 松井裕史, 下川治, 間宮孝, 溝上裕士, 兵頭一之介
- Journal Title
  
  日本レーザー医学会誌
  
  Volume: 35 Pages: 468-474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591024
[Journal Article] Qing Dai attenuates nonsteroidal anti-inflammatory drug-induced mitochondrial reactive oxygen species in gastrointestinal epithelial cells2015
- Author(s)
  Saito R, Tamura M, Matsui H, Nagano Y, Suzuki H, Kaneko T, Mizokami Y, Hyodo I.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 56 Issue: 1 Pages: 8-14
- DOI
  10.3164/jcbn.14-59
- NAID
  130004704975
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591024
[Journal Article] Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion2014
- Author(s)
  Masato Tamura, Hirofumi Matsui, Tsutomu Tomita, Hisato Sadakata, Hiroko P. Indo, Hideyuki J. Majima, Tsuyoshi Kaneko, Ichinosuke Hyodo.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 54 Issue: 1 Pages: 12-17
- DOI
  10.3164/jcbn.13-36
- NAID
  130004466736
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00241, KAKENHI-PROJECT-23592774, KAKENHI-PUBLICLY-24106503, KAKENHI-PROJECT-24591024
[Journal Article] Salt is an oxidative stressor for gastric epithelial cells.2013
- Author(s)
  Tamura M. Matsui H. Nagano Y. N. Kaneko T. Indo H. P. Majima H. J. and Hyodo I.
- Journal Title
  
  J Physiol Pharmacol
  
  Volume: 64 Pages: 89-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591024
[Journal Article] Alcohol is an oxidative stressor for gastric epithelial cells: detection of superoxide in living cells2013
- Author(s)
  Masato Tamura, Hirofumi Matsui, Tsuyoshi Kaneko and Ichinosuke Hyodo.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 53 Issue: 2 Pages: 75-80
- DOI
  10.3164/jcbn.13-32
- NAID
  130004466720
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J00241, KAKENHI-PROJECT-24591024
[Journal Article] Bishophonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation2012
- Author(s)
  Nagano Y, Matsui H, Shimokawa O, Nakamura Y, Tamura M, Rai K, Kaneko T, Hyodo I
- Journal Title
  
  J Clin Biochem Nutr
  
  Volume: 51(3) Pages: 196-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659576
[Journal Article] Cancer cells uptake porphyrins via heme carrier protein 12012
- Author(s)
  Kazuhiro Hiyama, Hirofumi Matsui, Masato Tamura, Osamu Shimokawa, Mariko Hiyama, Tsuyoshi Kaneko, Yumiko Nagano, Ichinosuke Hyodo, Junko Tanaka, Yoshihiro Miwa, Tetsuo Ogawa, Takeo Nakanishi and Ikumi Tamai
- Journal Title
  
  Journal of Porphyrins and Phthalocyanines
  
  Volume: 16 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659576
[Journal Article] NSAIDs and acidic environment induce gastric mucosal cellular mitochondrial dysfunction2012
- Author(s)
  Nagano Y, Matsui H, Tamura M, Shimokawa O, Nakamura Y, Kaneko T, Hyodo I
- Journal Title
  
  Digestion
  
  Volume: 85(2) Pages: 131-5
- NAID
  10031061679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659576
[Journal Article] Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID)-induced lipid peroxidation by the MnSOD overexpression in gastrointestinal epithelial cells.2012
- Author(s)
  Nagano Y, Matsui H, Shimokawa O, Tamura M, Rai K, Nakamura Y, Kaneko T, Indo HP, Majima HJ, Hyodo I.
- Journal Title
  
  J Physiol Pharmacol.
  
  Volume: 63 Pages: 137-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591024
[Journal Article] Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation2012
- Author(s)
  Nagano Y, Matsui H, Shimokawa O, Nakamura Y, Tamura M, Rai K, Kaneko T, Hyodo I.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 51 Issue: 3 Pages: 196-203
- DOI
  10.3164/jcbn.12-41
- NAID
  130004466701
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591024, KAKENHI-PROJECT-24591224, KAKENHI-PUBLICLY-24106503
[Journal Article] Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID)-induced lipid peroxidation by the MnSOD overexpression in gastrointestinal epithelial cells2012
- Author(s)
  Nagano Y, Matsui H, Shimokawa O, Tamura M, Rai K, Nakamura Y, Kaneko T, Indo HP, Majima HJ, Hyodo I
- Journal Title
  
  J Physiol Pharmacol
  
  Volume: 63 (2) Pages: 137-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659576
[Journal Article] Cancer cells uptake porphyrins via heme carrier protein 12012
- Author(s)
  Hiyama K, Matsui H, Kaneko T
- Journal Title
  
  Journal of Porphyrins and Phthalocyanines
  
  Volume: 16 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591024
[Journal Article] がん特異的ポルフィリン取り込みはNO→HIF-1α→EPO/EPOR→HCP-1によって誘導される2010
- Author(s)
  檜山和寛, 松井裕史, 長野由美子, 頼冠甫, 金子剛, 下川治, 兵頭一之介
- Journal Title
  
  G.I.Research
  
  Volume: 18巻 Pages: 376-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590717
[Journal Article] 【やっぱり大切、基本手技】上部消化管[治療]PDTの基本(解説/特集)2010
- Author(s)
  松井裕史,金子剛
- Journal Title
  
  消化器内視鏡 22巻
  
  Pages: 562-565
- Data Source
  KAKENHI-PROJECT-20590717
[Journal Article] 【色素内視鏡を見直す-画像強調観察法との比較】ALAを用いた胃癌の光線力学的診断2009
- Author(s)
  松井裕史,金子剛,中原朗,兵頭一之介
- Journal Title
  
  臨床消化器内科 24(10)
  
  Pages: 1379-1386
- Data Source
  KAKENHI-PROJECT-20590717
[Journal Article] ALAを用いた胃癌の光線力学的診断2009
- Author(s)
  松井裕史, 金子剛
- Journal Title
  
  臨床消化器内科 24巻
  
  Pages: 1379-1386
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] 【消化管症候群(第2版)その他の消化管疾患を含めて】食道食道腫瘍2009
- Author(s)
  中原朗、松井裕史、鈴木英雄、金子剛
- Journal Title
  
  日本臨床別冊
  
  Pages: 93-97
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] 【色素内視鏡を見直す画像強調観察法との比較】ALAを用いた胃癌の光線力学的診断2009
- Author(s)
  松井裕史、金子剛
- Journal Title
  
  臨床消化器内科 24巻
  
  Pages: 1379-1386
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] 【消化管症候群(第2版)その他の消化管疾患を含めて】食道食道dysplasia2009
- Author(s)
  中原朗、松井裕史、鈴木英雄、金子剛
- Journal Title
  
  日本臨床別冊
  
  Pages: 41-44
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] Neoplastic transformation and induction of H^+,K^+-adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line2008
- Author(s)
  O. Shimokawa, H. Matsui, Y. Nagano, T. Kaneko, T.
- Journal Title
  
  In Vitro Cellular & Developmental Biology 44(1-2)
  
  Pages: 26-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] アミノレブリン酸投与によるがん固有蛍光と一酸化窒素2008
- Author(s)
  松井裕史、宇土潤平、金子剛、下川治、兵頭一之介
- Journal Title
  
  日本レーザー医学会誌 29巻
  
  Pages: 153-159
- NAID
  10024378835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590717
[Journal Article] アミノレブリン酸投与によるがん固有蛍光と-酸化窒素2008
- Author(s)
  松井裕史、宇土潤平、金子剛他2人
- Journal Title
  
  日本レーザー医学会誌 29
  
  Pages: 153-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] Neoplastic transformation and induction of H+, K+ -adenosine triphosphatase by N-methyl-N'-nitro-N-nitrosoguanidine in the gastric epithelial RGM-1 cell line.2008
- Author(s)
  O. Shimokawa, H. Matsui, Y. Nagano, T. Kaneko 他7人
- Journal Title
  
  In Vitro Cellular & Developmental Biology 44
  
  Pages: 26-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890029
[Journal Article] アミノレブリン酸投与によるがん固有蛍光と一酸化窒素2008
- Author(s)
  松井裕史、宇土潤平、金子剛、下川治、兵頭一之介
- Journal Title
  
  日本レーザー医学会誌 Vol. 29
  
  Pages: 153-159
- NAID
  10024378835
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590717
[Patent] 大腸癌検出方法及び大腸癌検出キット・内視鏡2013
- Inventor(s)
  金子　剛
- Industrial Property Rights Holder
  金子　剛
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-002956
- Filing Date
  2013-01-10
- Data Source
  KAKENHI-PROJECT-24591024
[Patent] 大腸癌検出方法及び大腸癌検出キット2013
- Inventor(s)
  金子　剛
- Industrial Property Rights Holder
  金子　剛
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-002956
- Filing Date
  2013-01-10
- Data Source
  KAKENHI-PROJECT-24591024
[Patent] がん領域鮮鋭化薬剤2008
- Inventor(s)
  金子剛松井裕史
- Industrial Property Rights Holder
  金子剛松井裕史
- Filing Date
  2008-12-22
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] A new screening method for colon cancer by measuring iron concentration in the gut lavage fluid2013
- Author(s)
  Kaneko T, Matsui H, Mizokami Y
- Organizer
  DDW2013
- Place of Presentation
  Orlando, Florida（USA）
- Data Source
  KAKENHI-PROJECT-24591024
[Presentation] ミトコンドリア障害による消化管酸化ストレスとしてのNSAIDs投与と酸環境曝露2012
- Author(s)
  長野由美子、松井裕史、下川治、田村磨聖、中村幸夫、頼冠甫、金子剛、兵頭一之介
- Organizer
  第65回酸化ストレス学会
- Place of Presentation
  Y-3,徳島
- Year and Date
  2012-06-08
- Data Source
  KAKENHI-PROJECT-23659576
[Presentation] Salt as an oxidative stress in gastric mucosal cells2012
- Author(s)
  Matsui H, Tamura M, Nagano Y, Kaneko Tand Hyodo I
- Organizer
  7th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
- Place of Presentation
  Honolulu(USA)
- Year and Date
  2012-09-10
- Data Source
  KAKENHI-PROJECT-23659576
[Presentation] An Optical Diagnosis for Gastric Cancer with Fluorescence Observation2012
- Author(s)
  Kaneko T, Matsui H, Suzuki H, Narasaka T, Mizokami M and Hydo I
- Organizer
  5th International Gastrointestinal Consensus Symposium
- Place of Presentation
  Sendai
- Year and Date
  2012-02-11
- Data Source
  KAKENHI-PROJECT-23659576
[Presentation] Plenary Lecture Heme carrier protein 1 involves a cancer specific porphyrin accumulation2012
- Author(s)
  Matsui H, Kaneko T, Hyodo I
- Organizer
  221st ECS Meeting
- Place of Presentation
  Seattle(USA)
- Year and Date
  2012-05-08
- Data Source
  KAKENHI-PROJECT-23659576
[Presentation] Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation2012
- Author(s)
  Nagano Y, Matsui H, Shimokawa O, Hirayama A, Nakamura Y, Tamura M, Kaneko T and Hyodo I
- Organizer
  7th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
- Place of Presentation
  Honolulu(USA)
- Year and Date
  2012-09-10
- Data Source
  KAKENHI-PROJECT-23659576
[Presentation] An Optical Cancer Diagnosis with Fluorescence Polarization2012
- Author(s)
  Kaneko T, Matsui H.
- Organizer
  DDW2012
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-24591024
[Presentation] がん特異的ポルフィリン取り込み現象はHeme carrier protein 1を介して行われる2010
- Author(s)
  檜山和寛、金子剛、松井裕史
- Organizer
  日本光線力学会
- Place of Presentation
  福井AOSSA
- Year and Date
  2010-06-12
- Data Source
  KAKENHI-PROJECT-20590717
[Presentation] 米国消化器病週間 (DDW2009)2009
- Author(s)
  Kaneko T
- Organizer
  The fluorescence assessment of cellular membrane fluidity in human gastric cancer specimens
- Place of Presentation
  Chicago USA
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] The fluorescence assessment of cellular membrane fluidity in human gastric cancer specimens.2009
- Author(s)
  Kaneko T
- Organizer
  米国消化器病学会(第40回・DDW2009)
- Place of Presentation
  McCormick Place(Chicago・USA)
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] 蛍光偏光解消法によるNSAIDs起因性胃粘膜細胞傷害の捕捉2009
- Author(s)
  金子剛, ほか
- Organizer
  第27回サイトプロテクション研究会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] 「がん細胞の膜は柔らかい」-蛍光偏光解消法による光生物学的膜流動性の捕捉2009
- Author(s)
  金子剛
- Organizer
  第27回サイトプロテクション研究会
- Place of Presentation
  ホテルグランヴィア(京都)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] Nitoric Oxide Mediates the Warburg Effect in Gastric Epithelial and Cancer cells2008
- Author(s)
  H. Matsui, O. Shimokawa, T. kaneko 他6人
- Organizer
  第108回米国消化器病学会
- Place of Presentation
  サンディエゴ
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] Cell membrane fluidity assays of fluorescence anisotropy and excimer formation in indomethacin-treated gastric epithelial cell-line RGM-12008
- Author(s)
  T. kaneko
- Organizer
  A Joint Conference of 13th In Vivo EPR Spectroscopy and Imaging 10th International EPR Spin Trapping/Spin Labeling
- Place of Presentation
  福岡
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] Malignant Transtbrmation of Rat Gastric Epithelial RGM-1 Cell Line Induced By Carcinogen N-methyl-N'-nitro-Nnitrosoguanidine treatment Was Accompanied with the Ectopic Expression of H+. K+Adenosine Trinhosnhatase2008
- Author(s)
  O. Shimokawa, H. Matsui, T. kaneko 他6人
- Organizer
  第108回米国消化器病学会
- Place of Presentation
  サンデイエゴ
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] 米国消化器病週間 (DDW2008)2008
- Author(s)
  Shimokawa O, Kaneko T
- Organizer
  Malignant Transformation of Rat Gastric Epithelial RGM-1 Cell Line Induced By Carcinogen N-methyl-N-nitro-N-Nitroso -guanidine treatment Was Accompanied with the Ectopic Expression of H^+, K^+ Adenosine Triphosphatase
- Place of Presentation
  San Diego USA
- Year and Date
  2008-05-21
- Data Source
  KAKENHI-PROJECT-20890029
[Presentation] The cancer treatment in aging society
- Author(s)
  Tsuyoshi Kaneko
- Organizer
  The 1st Japan-Tajikistan symposium on science, technology and innovation
- Place of Presentation
  Dushanbe, Tajikistan
- Year and Date
  2015-03-19 – 2015-03-22
- Invited
- Data Source
  KAKENHI-PROJECT-24591024

1. MATSUI Hirofumu (70272200)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results

KANEKO Tsuyoshi 金子 剛

Research Projects

Research Products

Co-Researchers

An Optical Cancer Diagnosis with Fluorescence Polarization.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A new tracer development for positron emission tomographic imaging with an isotope62Zn containing porphyrins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A screening test using urinal porphyrins for gastric cancer patients.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The Possibility of Cancer Diagnosis with Fluidity Sensitive Fluorescence MeasurementPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 超高齢社会におけるレーザー治療の意義 高齢者に対する消化器領域の光線力学療法2015

Author(s)

Journal Title

Data Source

[Journal Article] Qing Dai attenuates nonsteroidal anti-inflammatory drug-induced mitochondrial reactive oxygen species in gastrointestinal epithelial cells2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Salt is an oxidative stressor for gastric epithelial cells.2013

Author(s)

Journal Title

Data Source

[Journal Article] Alcohol is an oxidative stressor for gastric epithelial cells: detection of superoxide in living cells2013

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Bishophonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation2012

Author(s)

Journal Title

Data Source

[Journal Article] Cancer cells uptake porphyrins via heme carrier protein 12012

Author(s)

Journal Title

Data Source

[Journal Article] NSAIDs and acidic environment induce gastric mucosal cellular mitochondrial dysfunction2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Rebamipide attenuates nonsteroidal anti-inflammatory drugs (NSAID)-induced lipid peroxidation by the MnSOD overexpression in gastrointestinal epithelial cells.2012

Author(s)

Journal Title

Data Source

[Journal Article] Bisphosphonate-induced gastrointestinal mucosal injury is mediated by mitochondrial superoxide production and lipid peroxidation2012

Author(s)

Journal Title

KANEKO Tsuyoshi 金子剛

[Journal Article] 超高齢社会におけるレーザー治療の意義高齢者に対する消化器領域の光線力学療法2015

[Journal Article] 【消化管症候群(第2版)その他の消化管疾患を含めて】食道食道腫瘍2009

[Journal Article] 【色素内視鏡を見直す画像強調観察法との比較】ALAを用いた胃癌の光線力学的診断2009

[Journal Article] 【消化管症候群(第2版)その他の消化管疾患を含めて】食道食道dysplasia2009