onodera taishi 小野寺大志

… Alternative Names

Onodera Taishi 小野寺大志

ONODERA Taishi 小野寺大志

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Researcher Number	90513143
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所ワクチン開発研究センター, 室長
Affiliation (based on the past Project Information) *help	2024: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 主任研究官 2017 – 2020: 国立感染症研究所, 免疫部, 主任研究官 2015: 国立感染症研究所, その他部局等, 研究員 2013 – 2015: 国立感染症研究所, その他部局等, 主任研究官 2011 – 2012: 国立感染症研究所, 免疫部, 主任研究官
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related Except Principal Investigator Immunology
Keywords	Principal Investigator ワクチン / インフルエンザ / 抗体 / 長期生存型抗体産生細胞 / 免疫記憶 / ウイルス感染 / 免疫学 / インフルエンザウイルス / 記憶B細胞 / Single RNA seq … More / Bリンパ球 / I型IFNシグナル / ウイルス感染症 / 抗体産生細胞 / B細胞 / インフルエンザウイルス感染症 / 感染症 / インフルエンザ感染 / 記憶免疫応答 / Toll様受容体 … More Except Principal Investigator 免疫学 / 抗体 / B細胞 / 腸内細菌 / インフルエンザ Less

Bioinformatics infrastructure of memory B cells for sustainability and broad reactivity against vaccinesPrincipal Investigator
- Principal Investigator
  
  小野寺大志
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Institute of Infectious Diseases
Development of the induction method of the long-lived plasma cells for new vaccine strategiesPrincipal Investigator
- Principal Investigator
  
  Onodera Taishi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Infectious Diseases
Regulation of influenza protective antibody responses by microbiota
- Principal Investigator
  
  Takahashi Yoshimasa
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  National Institute of Infectious Diseases
Maintenace mechanisms of long-lived plasma cells in influenza infectious diseasePrincipal Investigator
- Principal Investigator
  
  Onodera Taishi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Infectious Diseases
Elucidation of new reactivation mechanisms of influenza virus specific memory B cells in mouse model for influenza infectionPrincipal Investigator
- Principal Investigator
  
  ONODERA Taishi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  National Institute of Infectious Diseases

All 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] B細胞内因性TLRシグナルによるB細胞応答の制御機構、臨床免疫・アレルギー科58巻2012
- Author(s)
  小野寺大志、高橋宜聖、小林和夫
- Data Source
  KAKENHI-PROJECT-23790553
[Journal Article] Myeloid cell dynamics correlating with clinical outcomes of severe COVID-19 in Japan2021
- Author(s)
  2.Takano T, Matsumura T, Adachi Y, Terahara K, Moriyama S, Onodera T, Nishiyama A, Kawana-Tachikawa A, Miki S, Hosoya-Nakayama K, Nakamura-Hoshi M, Seki S, Tachikawa N, Yoshimura Y, Miyata N, Horiuchi H, Sasaki H, Miyazaki K, Kinoshita N, Sudo T, Akiyama Y, Sato R, Suzuki T, Matano T, Takahashi Y
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 4 Pages: 241-247
- DOI
  10.1093/intimm/dxab005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08895
[Journal Article] Association of Human Leukocyte Antigen DRB1*09:01 with severe COVID-192021
- Author(s)
  3.Anzurez A, Naka I, Miki S, Hosoya-Nakayama K, Isshiki M, Watanabe Y, Nakamura-Hoshi M, Seki S, Matsumura T, Takano T, Onodera T, Tanaka K, Takahashi Y, Suzuki T, Matano T, Ohashi J, Kawana-Tachikawa A.
- Journal Title
  
  HLA
  
  Volume: 18 Issue: 1 Pages: 1-6
- DOI
  10.1111/tan.14256
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08895
[Journal Article] Identification of Two Critical Neutralizing Epitopes in the Receptor Binding Domain of Hepatitis B Virus preS12020
- Author(s)
  Yato Keigo、Onodera Taishi、Matsuda Mami、Moriyama Saya、Fujimoto Akira、Watashi Koichi、Aizaki Hideki、Tanaka Tomohisa、Moriishi Kohji、Nishitsuji Hironori、Shimotohno Kunitada、Tamura Koji、Takahashi Yoshimasa、Wakita Takaji、Muramatsu Masamichi、Kato Takanobu、Suzuki Ryosuke
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 5
- DOI
  10.1128/jvi.01680-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07583, KAKENHI-PROJECT-20K08380, KAKENHI-PROJECT-17K08895, KAKENHI-PROJECT-18K07161
[Journal Article] Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope2019
- Author(s)
  Bajic G, Maron MJ, Adachi Y, Onodera T, McCarthy KR, McGee CE, Sempowski GD, Takahashi Y, Kelsoe G, Kuraoka M, Schmidt AG.Influenza
- Journal Title
  
  Cell Host and Microbe
  
  Volume: 25(6) Issue: 6 Pages: 827-835
- DOI
  10.1016/j.chom.2019.04.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08895, KAKENHI-PROJECT-19K17656
[Journal Article] Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses2019
- Author(s)
  Onodera T, Hashi K, Shukla RK, Miki M, Takai-Todaka R, Fujimoto A, Kuraoka M, Miyoshi T, Kobayashi K, Hasegawa H, Ato M, Kelsoe G, Katayama K, Takahashi Y
- Journal Title
  
  Journal of Immunology
  
  Volume: 203(12) Issue: 12 Pages: 3282-3292
- DOI
  10.4049/jimmunol.1900481
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08895
[Journal Article] Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism2019
- Author(s)
  Watanabe A, McCarthy KR, Kuraoka M, Schmidt AG, Adachi Y, Onodera T, Tonouchi K, Caradonna TM, Bajic G, Song S, McGee CE, Sempowski GD, Feng F, Urick P, Kepler TB, Takahashi Y, Harrison SC, Kelsoe G.Influenza
- Journal Title
  
  Cell
  
  Volume: 177(5) Issue: 5 Pages: 1124-1135
- DOI
  10.1016/j.cell.2019.03.048
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08895, KAKENHI-PROJECT-19K17656
[Journal Article] Adaptive B cell responses to influenza virus infection in the lung.2017
- Author(s)
  Takahashi, Y., Onodera, T., Adachi, Y., Ato, M
- Journal Title
  
  Viral Immunology
  
  Volume: 30 Issue: 6 Pages: 431-437
- DOI
  10.1089/vim.2017.0025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08895, KAKENHI-PROJECT-16K19167
[Journal Article] Whole-Virion Influenza Vaccine Recalls an Early Burst of High-Affinity Memory B Cell Response through TLR Signaling2016
- Author(s)
  Taishi Onodera, Akira Hosono, Takato Odagiri, Masato Tashiro, Shuichi Kaminogawa, Yoshinobu Okuno, Tomohiro Kurosaki, Manabu Ato, Kazuo Kobayashi, and Yoshimasa Takahashi
- Journal Title
  
  Journal of Immunology
  
  Volume: 196(10) Issue: 10 Pages: 4172-84
- DOI
  10.4049/jimmunol.1600046
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860377, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-16K15289
[Journal Article] Primary and Secondary B-Cell Responses to Pulmonary influenza infection.2012
- Author(s)
  Yoshimasa Takahashi, Taishi Onodera, Kazuo Kobayashi, Tomohiro Kurosaki
- Journal Title
  
  Infectious Disorders Drug Targets
  
  Volume: 12 Pages: 232-40
- Data Source
  KAKENHI-PROJECT-23790553
[Journal Article] Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection.2012
- Author(s)
  Taishi Onodera, Yoshimasa Takahashi, Yusuke Yokoi, Manabu Ato, Yuichi Kodama, Satoshi Hachimura, Tomohiro Kurosaki, Kazuo Kobayashi
- Journal Title
  
  PNAS
  
  Volume: 109(7) Pages: 2485-90
- Data Source
  KAKENHI-PROJECT-23790553
[Journal Article] Primary and Secondary B-Cell Responses to Pulmonary Virus Infection2012
- Author(s)
  Yoshimasa Takahashi, Taishi Onodera, Kazuo Kobayashi, Tomohiro Kurosaki
- Journal Title
  
  Infect Disorders Drug Targets
  
  Volume: Vol 12, Issue 3 Pages: 232-240
- Data Source
  KAKENHI-PROJECT-23790553
[Journal Article] Primary and Secondary B-Cell Responses to Pulmonary Virus Infection.2012
- Author(s)
  Yoshimasa Takahashi, Taishi Onodera, Kazuo Kobayashi, Tomohiro Kurosaki
- Journal Title
  
  Infectious Disorders Drug Targets
  
  Volume: Vol12 Pages: 232-240
- Data Source
  KAKENHI-PROJECT-23790553
[Journal Article] B 細胞内因性TLRシグナルによる B 細胞応答の制御機構2012
- Author(s)
  小野寺大志、高橋宜聖、小林和夫
- Journal Title
  
  臨床免疫アレルギー科
  
  Volume: 第58巻
- Data Source
  KAKENHI-PROJECT-23790553
[Journal Article] Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection2012
- Author(s)
  Onodera, T., Takahashi, Y., Yokoi, Y., Ato, M., Kodama, Y., Hachimura, S., Kurosaki, T., and Kobayashi, K
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 109 Issue: 7 Pages: 2485-90
- DOI
  10.1073/pnas.1115369109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229007, KAKENHI-PROJECT-23380073, KAKENHI-PROJECT-23790553
[Journal Article] Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection.2012
- Author(s)
  Taishi Onodera, Yoshimasa Takahashi, Yusuke Yokoi, Manabu Ato, Yuichi Kodama, Satoshi Hachimura, Tomohiro Kurosaki, Kazuo Kobayashi
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States
  
  Volume: Vol109 Pages: 2485-2490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] Virus-like particle structure enhances protective IgA antibody responses against noroviruses2018
- Author(s)
  Taishi Onodera, Manabu Ato, Yoshimasa Takahashi
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-17K08895
[Presentation] Regulation of antibody breadth to mutating viruses through distinct germinal center selection.2017
- Author(s)
  Takahashi, Y., Adachi, Y., Onodera, T., Ato, M.
- Organizer
  The 16th Awaji International Forum on Infection and Immunity
- Invited
- Data Source
  KAKENHI-PROJECT-16K15296
[Presentation] Follicular helper NKT cells induce protective effect of a protein-based pneumococcal vaccine through stimulation of IgG production by B cells.2016
- Author(s)
  Nakahara M, Takatsuka S, Ueno K, Onodera T, Takahashi Y, Kawakami K, Kubo M, Kinjo Y
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-16K15296
[Presentation] Broadly cross-reactive human memory B cells against norovirus express dual B cell antigen receptors.2016
- Author(s)
  Onodera T, Ato M, Takahashi T
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-16K15296
[Presentation] Distinct germinal center selection at local sites shapes memory B cell response to viral escape2015
- Author(s)
  ADACHI Yu, ONODERA Taishi, ATO Manabu, TAKAHASHI Yoshimasa
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25860377
[Presentation] Visualization of anti-nuclearAb producing B cells by flow-cytometry in a SLE mouse model2015
- Author(s)
  ONODERA Taishi, ADACHI Takahiro, TSUBATA Takeshi, ATO Manabu, TAKAHASHI Yoshimasa
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25860377
[Presentation] Intravital imaging of Ca2+ signals in lymphocytes of the Ca2+ biosensor YC3.60 transgenic mice2015
- Author(s)
  ADACHI Takahiro, YOSHIKAWA Soichiro, KARASUYAMA Hajime, ONODERA Taishi, TAKAHASHI Yoshimasa, KIKUTA Junichi, ISHI Masaru, TEDDER F. Tomas
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25860377
[Presentation] B-cell intrinsic Toll-like receptor signaling accelerates memory B cell response to booster influenza Vaccination2013
- Author(s)
  Taishi Onodera, Tomohiro Kurosaki, Kazuo, Kobayashi, Yoshimasa Takahashi
- Organizer
  Keystone Symposia B cell development and function
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] Replenishment of Long-Live Plasma Cells is constitutively restricted by CD4+T cells in their maintenance phase after influenza vaccination2013
- Author(s)
  Taishi Onodera, ADACHI Takahiro, TSUBATA Takeshi, KUROSAKI Tomohiro, ADACHI Yu, ATO Manabu, TAKAHASHI Yoshimasa
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  千葉県千葉市　幕張メッセ
- Data Source
  KAKENHI-PROJECT-25860377
[Presentation] B-cell intrinsic Toll-like receptor signaling accelerates memory B cell response to booster influenza vaccination2013
- Author(s)
  Taishi Onodera, Tomohiro Kurosaki, Kazuo Kobayashi,Yoshimasa Takahashi
- Organizer
  Keystone Symposia
- Place of Presentation
  Keystone、Denver, USA
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection2012
- Author(s)
  Takahashi, Y.Onodera, T., Yokoi, Y., Ato, M.,Hachimura, S., Kurosaki, T., Kobayashi, K
- Organizer
  Keystone symposia, Viral Immunity and Host Gene Influence
- Place of Presentation
  Colorado, USA
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] B-cell intrinsic Toll-like receptor signaling accelerates memory B cell response to booster influenza Vaccination2012
- Author(s)
  Taishi Onodera, Tomohiro Kurosaki, Kazuo, Kobayashi, Yoshimasa Takahashi
- Organizer
  The 41^<th> JSI annual meeting
- Place of Presentation
  Kobe
- Year and Date
  2012-05-07
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] Role of Toll-like receptor signaling for the development and reactivation of virus-specific memory B cells2011
- Author(s)
  ONODERA Taishi, AIZAWA Ryutaro, HOSONO Akira, KAMINOGAWA Shuichi, KOBAYASHI Kazuo, TAKAHASHI Yoshimasa
- Organizer
  The 40^<th> JSI annual meeting
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] Protective memory B cell responses to influenza virus infection2011
- Author(s)
  Takahashi, Y., Onodera, T., Yokoi, Y., Kurosaki, T., Kobayashi, K.
- Organizer
  The 40^<th> JSI annual meeting
- Place of Presentation
  Chiba
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] CD273+ memory B cells replenish bone marrow plasma cells in the steady state after influenza vaccination
- Author(s)
  Taishi Onodera, Takahiro Adachi, Takeshi Tsubata, Tomohiro Kurosaki, Yu Adachi, Manabu Ato, Yoshimasa Takahashi
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25860377
[Presentation] Protective memory B cell responses to influenza virus infection
- Author(s)
  Takahashi, Y., Onodera, T., Yokoi, Y., Kurosaki, T., Kobayashi, K
- Organizer
  日本免疫学会総会(招待講演)
- Place of Presentation
  千葉県　幕張メッセ
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection
- Author(s)
  Takahashi, Y.Onodera, T., Yokoi, Y., Ato, M., Hachimura, S., Kurosaki, T., Kobayashi, K.
- Organizer
  Keystone symposia, Viral Immunity and Host Gene Influence(招待講演)
- Place of Presentation
  Colorado, USA
- Data Source
  KAKENHI-PROJECT-23790553
[Presentation] B細胞内因性TLRシグナルによるインフルエンザワクチンの奏功機序
- Author(s)
  小野寺大志、田代眞人、黒崎知博、阿戸学、高橋宜聖
- Organizer
  第7回アジュバント研究会
- Place of Presentation
  大阪府豊中市　千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-25860377
[Presentation] Role of Toll-like receptor signaling for the development and reactivation of virus-specific memory B cells
- Author(s)
  ONODERA Taishi, AIZAWA Ryutaro,　 HOSONO Akira, KAMINOGAWA Shuichi, KOBAYASHI Kazuo, TAKAHASHI Yoshimasa
- Organizer
  日本免疫学会総会
- Place of Presentation
  千葉県　幕張メッセ
- Data Source
  KAKENHI-PROJECT-23790553

1. Takahashi Yoshimasa (60311403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 八村敏志 (40238019)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 村松正道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 黒崎知博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

onodera taishi 小野寺 大志

Onodera Taishi 小野寺 大志

ONODERA Taishi 小野寺 大志

Research Projects

Research Products

Co-Researchers

Bioinformatics infrastructure of memory B cells for sustainability and broad reactivity against vaccinesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the induction method of the long-lived plasma cells for new vaccine strategiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of influenza protective antibody responses by microbiota

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maintenace mechanisms of long-lived plasma cells in influenza infectious diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of new reactivation mechanisms of influenza virus specific memory B cells in mouse model for influenza infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] B細胞内因性TLRシグナルによるB細胞応答の制御機構、臨床免疫・アレルギー科58巻2012

Author(s)

Data Source

[Journal Article] Myeloid cell dynamics correlating with clinical outcomes of severe COVID-19 in Japan2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of Human Leukocyte Antigen DRB1*09:01 with severe COVID-192021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Two Critical Neutralizing Epitopes in the Receptor Binding Domain of Hepatitis B Virus preS12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adaptive B cell responses to influenza virus infection in the lung.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Whole-Virion Influenza Vaccine Recalls an Early Burst of High-Affinity Memory B Cell Response through TLR Signaling2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Primary and Secondary B-Cell Responses to Pulmonary influenza infection.2012

onodera taishi 小野寺大志

Onodera Taishi 小野寺大志

ONODERA Taishi 小野寺大志