OHNISHI HIROYUKI 大西浩之

… Alternative Names

OHNISHI Hiroyuki 大西浩之

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Researcher Number	90523316
Affiliation (Current)	2025: 大阪夕陽丘学園短期大学, その他部局等, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 北里大学, 医療衛生学部, 講師 2012 – 2015: 金城学院大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Biological pharmacy / General pharmacology Except Principal Investigator Eating habits / Basic Section 08030:Family and consumer sciences, and culture and living-related
Keywords	Principal Investigator マンノース受容体 / 肝細胞増殖因子 / M2マクロファージ / STAT3 / IL-4 / IL-10 / Mannose receptor / HGF / HGF-β / 貪食作用 / マクロファージ … More Except Principal Investigator … More 多価不飽和脂肪酸 / サチャインチオイル / 食用植物油 / 高血圧 / トコフェロール / 肥満 / n-3系多価不飽和脂肪酸 / 生活習慣病 / α－リノレン酸 / 食と栄養 / アミロイドβ / 細胞死 / 認知症 / シナプス小胞 / 神経保護 / 神経栄養因子 / ストレス / 周産期 / 脳神経系 Less

Analysis of the effects of novel n-3 polyunsaturated fatty acid-containing edible vegetable oils on lifestyle-related diseases
- Principal Investigator
  
  Naito Yukiko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Kitasato University
Basic research on improvement of lipid nutrition for dementia
- Principal Investigator
  
  Miyazawa Daisuke
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Kinjo Gakuin University
Regulation of macrophage immune response by HGF-beta/mannose receptor axis.Principal Investigator
- Principal Investigator
  
  OHNISHI Hiroyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kinjo Gakuin University
Basic study on improvement of lipid nutrition for perinatal mental disorder
- Principal Investigator
  
  MIYAZAWA Dasiuke
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Kinjo Gakuin University
Molecular mechanisms of HGF-beta-induced macrophage phagocytosisPrincipal Investigator
- Principal Investigator
  
  OHNISHI Hiroyuki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kinjo Gakuin University

All 2019 2018 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis. In"Biochemical Basis and Therapeutic Implications of Angiogenesis"2013
- Author(s)
  Ohnishi H, Oka K, Mizuno S, Nakamura T
- Publisher
  Springer Science + Business Media New York
- Data Source
  KAKENHI-PROJECT-24790250
[Book] Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis2013
- Author(s)
  Ohnishi H, Oka K, Mizuno S, Nakamura T.
- Total Pages
  30
- Publisher
  Springer Science+Business Media New York. (印刷中)
- Data Source
  KAKENHI-PROJECT-24790250
[Journal Article] 糠漬けに伴うナスの物性変化と品種間差2019
- Author(s)
  大西浩之、宮澤大介、吉岡弘毅
- Journal Title
  
  大阪夕陽丘学園短期大学紀要
  
  Volume: 62 Pages: 53-60
- NAID
  40022116601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K00876
[Journal Article] Stromal cell-derived factor-1 (SDF1)-dependent recruitment of bone marrow-derived renal endothelium-like cells in a mouse model of acute kidney injury2015
- Author(s)
  Ohnishi H, Mizuno S, Mizuno-Horikawa Y and Kato T.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 77 Issue: 3 Pages: 313-319
- DOI
  10.1292/jvms.14-0562
- NAID
  130005060999
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860046, KAKENHI-PROJECT-26860268, KAKENHI-PROJECT-23590458
[Journal Article] Dissociation of c-Met phosphotyrosine sites in human cells in response to mouse hepatocyte growth factor but not human hepatocyte growth factor : the possible roles of different amino acids in different species2013
- Author(s)
  Ikebuchi F, Oka K, Mizuno S, Fukuta K, Hayata D, Ohnishi H, Nakamura T
- Journal Title
  
  Cell Biochem. Funct
  
  Volume: 31 Pages: 298-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790250
[Journal Article] Dissociation of c-Met phospho-tyrosine sites in human cells in response to mouse HGF, but not human HGF: The possible roles of different amino acids in different species.2013
- Author(s)
  Ikebuchi F, Oka K, Mizuno S, Fukuta K, Hayata D, Ohnishi H and Nakamura T:
- Journal Title
  
  Cell Biochem Function
  
  Volume: 31 Issue: 4 Pages: 298-304
- DOI
  10.1002/cbf.2898
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590458, KAKENHI-PROJECT-24790250
[Journal Article] Identification of mannose receptor as a receptor for HGFβ-chain : A novel ligand-receptor pathway for enhancing macrophage phagocytosis2012
- Author(s)
  Ohnishi H, Oka K, Mizuno S and NakamuraT.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Issue: 16 Pages: 13371-13381
- DOI
  10.1074/jbc.m111.318568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390079, KAKENHI-PROJECT-24790250
[Journal Article] Identification of mannose receptor as receptor for hepatocyte growth factorβ-chain : novel ligand-receptor pathway for enhancing macrophage phagocytosis2012
- Author(s)
  Ohnishi H, Oka K, Mizuno S, Nakamura T
- Journal Title
  
  J. Biol. Chem
  
  Volume: 287 Pages: 13371-1381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] Effects of butyrate-producing probiotics administration on obesity progression in ob/ob mice2019
- Author(s)
  内藤由紀子．大西浩之
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K02227
[Presentation] Effects of sacha inchi oil intake on lifestyle-related diseases in mice2018
- Author(s)
  Yukiko Naito, Hiroyuki Ohnishi, Naoki Ohara
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K02227
[Presentation] Canola oil toxicity in SHRSP and its sex difference2018
- Author(s)
  Naoki Ohara, Mai Nishikawa, Risako Ninomiya, Yukiko Naito, Kenjiro Tatematsu, Toshiaki Saito, Daisuke Miyazawa, Yoko Hashimoto, Hiroyuki Ohnishi, Harumi Okuyama
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K02227
[Presentation] 親の食餌脂肪酸が乳仔マウス脳のプロテインキナーゼに及ぼす影響2016
- Author(s)
  宮澤大介、大西浩之、浅井香穗、岩田真由香、郭麻美、北森一哉、山田和代、大原直樹、奥山治美
- Organizer
  日本病院薬剤師会東海ブロック・日本薬剤師会東海支部　合同学術大会2016
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-16K00876
[Presentation] 親の食餌脂肪酸が乳仔マウス脳のプロテインキナーゼに及ぼす影響2016
- Author(s)
  宮澤大介、大西浩之、浅井香穗、岩田真由香、郭麻美、北森一哉、山田和代、大原直樹、奥山治美
- Organizer
  日本病院薬剤師会東海ブロック・日本薬剤師会東海支部　合同学術大会2016
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] カノーラ油摂取がSHRSPのステロイドホルモン代謝に及ぼす影響 Changes by canola (rapeseed) oil ingestion of steroid hormone metabolism in SHRSP2016
- Author(s)
  八木聡美、西川真衣、花井仁美、鈴村紗世、内藤由紀子、立松憲次郎、宮澤大介、橋本洋子、山村彩、大西浩之、大原直樹、奥山治美
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-26860046
[Presentation] ２種のWistar系ラットに高脂肪食の及ぼす影響2016
- Author(s)
  山田和代、黒田詩織、後藤芹菜、大西浩之、宮澤大介、津嶋宏美、大久保剛、日比野英彦、大原直樹、奥山治美
- Organizer
  日本脂質栄養学会　第25回大会
- Place of Presentation
  秋田
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-16K00876
[Presentation] 親の食餌脂肪酸が乳仔マウス脳の神経栄養因子産生とプロテインキナーゼに及ぼす影響2016
- Author(s)
  宮澤大介、大西浩之、浅井香穗、岩田真由香、郭麻美、北森一哉、山田和代、大原直樹、奥山治美
- Organizer
  日本脂質栄養学会　第25回大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-16K00876
[Presentation] 親の食餌脂肪酸が乳仔マウス脳の神経栄養因子産生とプロテインキナーゼに及ぼす影響2016
- Author(s)
  宮澤大介、大西浩之、浅井香穗、岩田真由香、郭麻美、北森一哉、山田和代、大原直樹、奥山治美
- Organizer
  日本脂質栄養学会　第25回大会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] Changes by canola (rapeseed) oil ingestion of steroid hormone production in SHRSP2016
- Author(s)
  S Yagi, M Nishikawa, H Hanai, S Suzumura, Y Naito, K Tatematsu, D Miyazawa, Y Hashimoto, A Yamamura, H Ohnishi, N Ohara, H Okuyama
- Organizer
  日本薬理学会第89回年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] ２種のWistar系ラットに高脂肪食の及ぼす影響2016
- Author(s)
  山田和代、黒田詩織、後藤芹菜、大西浩之、宮澤大介、津嶋宏美、大久保剛、日比野英彦、大原直樹、奥山治美
- Organizer
  日本脂質栄養学会　第25回大会
- Place of Presentation
  秋田
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] カノーラ油の有害効果－SHRSPのステロイドホルモン代謝におよぼす影響－2015
- Author(s)
  花井仁美、西川真衣、髙木彩菜、寺町仁那、立松憲次郎、宮澤大介、橋本洋子、山村彩、大西浩之、大原直樹、奥山治美
- Organizer
  日本薬病院剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  名古屋
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26860046
[Presentation] カノーラ油の有害効果　　－SHRSPのステロイドホルモン代謝におよぼす影響－2015
- Author(s)
  花井仁美、西川真衣、髙木彩菜、寺町仁那、立松憲次郎、宮澤大介、橋本洋子、山村　彩、大西浩之、大原直樹、奥山治美
- Organizer
  日本薬病院剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  名古屋
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] HGF-β鎖/マンノース受容体系はIL-4-STAT3シグナルの亢進によりマクロファージからのIL-10産生を高める2015
- Author(s)
  大西浩之、宮澤大介、小島亜衣梨、山田和代、水谷秀樹、岡清正、水野信哉、大原直樹、中村敏一
- Organizer
  第79回日本生化学会中部支部例会
- Place of Presentation
  松本
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26860046
[Presentation] がん細胞・マクロファージ間相互作用におけるc-Metとマンノース受容体の機能解析2015
- Author(s)
  大西浩之、稲山里美、宮澤大介、山田和代、水谷秀樹、大原直樹
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  名古屋
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26860046
[Presentation] 親の食餌脂肪酸が乳仔マウス脳の神経栄養因子産生に及ぼす影響2014
- Author(s)
  宮澤大介、大西浩之、内田優希、坂本康子、木村愛莉、木村里奈、山田和代、北森一哉、大原直樹
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] HGFβ鎖/マンノース受容体系がマクロファージのサイトカイン産生に及ぼす影響2014
- Author(s)
  大西浩之、小島亜衣梨、宮澤大介、山田和代、大原直樹、水谷秀樹、岡清正、水野信哉、中村敏一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-25350151
[Presentation] 炎症性プロテアーゼによるHGF断片化で生じたHGFβ鎖の生物活性2013
- Author(s)
  大西浩之
- Organizer
  名古屋市立大学第137回薬学談話会
- Place of Presentation
  名古屋市立大学薬学部
- Invited
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] 炎症性プロテアーゼによるHGF断片化で生じたHGFβ鎖の生物活性2013
- Author(s)
  大西浩之
- Organizer
  第137回薬学談話会
- Place of Presentation
  名古屋市立大学(愛知県)
- Year and Date
  2013-06-12
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] HGF β-chain受容体としてのマンノース受容体の同定2012
- Author(s)
  大西浩之、岡清正、水野信哉、中村敏一
- Organizer
  第58回日本薬学会東海支部会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] HGFβ-chain受容体としてのマンノースレセプターの同定と新規貪食促進機構の可能性2012
- Author(s)
  大西浩之, 岡清正, 水野信哉, 中村敏一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡県)
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] HGF-β受容体としてのマンノースレセプターの同定と新規貪食促進機構の可能性2012
- Author(s)
  大西浩之、岡清正、水野信哉、中村敏一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] HGFβ-chain受容体としてのマンノース受容体の同定2012
- Author(s)
  大西浩之, 岡清正, 水野信哉, 中村敏一
- Organizer
  第58回日本薬学会東海支部会
- Place of Presentation
  静岡県立大学(静岡県)
- Year and Date
  2012-07-07
- Data Source
  KAKENHI-PROJECT-24790250
[Presentation] HGF-β鎖/マンノース受容体系がマクロファージのサイトカイン産生に及ぼす影響
- Author(s)
  大西浩之、小島亜衣梨、宮澤大介、山田和代、大原直樹、水谷秀樹、岡清正、水野信哉、中村敏一
- Organizer
  第87回　日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26860046

1. MIYAZAWA Dasiuke (70434553)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. OHARA Naoki (20426422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. YAMADA Kazuyo (90080217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. Naito Yukiko (80426428)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 水野信哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 岡清正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中村敏一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OHNISHI HIROYUKI 大西 浩之

OHNISHI Hiroyuki 大西 浩之

Research Projects

Research Products

Co-Researchers

Analysis of the effects of novel n-3 polyunsaturated fatty acid-containing edible vegetable oils on lifestyle-related diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Basic research on improvement of lipid nutrition for dementia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of macrophage immune response by HGF-beta/mannose receptor axis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study on improvement of lipid nutrition for perinatal mental disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of HGF-beta-induced macrophage phagocytosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis. In"Biochemical Basis and Therapeutic Implications of Angiogenesis"2013

Author(s)

Publisher

Data Source

[Book] Physiological Roles and Therapeutic Implications of Hepatocyte Growth Factor for Angiogenesis2013

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] 糠漬けに伴うナ スの物性変化と品種間差2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Stromal cell-derived factor-1 (SDF1)-dependent recruitment of bone marrow-derived renal endothelium-like cells in a mouse model of acute kidney injury2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Dissociation of c-Met phosphotyrosine sites in human cells in response to mouse hepatocyte growth factor but not human hepatocyte growth factor : the possible roles of different amino acids in different species2013

Author(s)

Journal Title

Data Source

[Journal Article] Dissociation of c-Met phospho-tyrosine sites in human cells in response to mouse HGF, but not human HGF: The possible roles of different amino acids in different species.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of mannose receptor as a receptor for HGFβ-chain : A novel ligand-receptor pathway for enhancing macrophage phagocytosis2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of mannose receptor as receptor for hepatocyte growth factorβ-chain : novel ligand-receptor pathway for enhancing macrophage phagocytosis2012

Author(s)

Journal Title

Data Source

[Presentation] Effects of butyrate-producing probiotics administration on obesity progression in ob/ob mice2019

Author(s)

Organizer

Data Source

[Presentation] Effects of sacha inchi oil intake on lifestyle-related diseases in mice2018

OHNISHI HIROYUKI 大西浩之

OHNISHI Hiroyuki 大西浩之

[Journal Article] 糠漬けに伴うナスの物性変化と品種間差2019

[Presentation] カノーラ油の有害効果　　－SHRSPのステロイドホルモン代謝におよぼす影響－2015