ASADA Hiromi 浅田裕美

Researcher Number	90526906
Affiliation (based on the past Project Information) *help	2014 – 2017: 山口大学, 医学部附属病院, 講師 2010 – 2013: 山口大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 子宮筋腫 / DNAメチル化 / 生殖医学 / MED12遺伝子 / 異種移植 / エストロゲンレセプターα Except Principal Investigator 活性酸素 / 加齢 / 卵子 / 卵巣 / メラトニン

MED12遺伝子の突然変異の有無による子宮筋腫発生機序の違いの解析Principal Investigator
- Principal Investigator
  
  浅田裕美
- Project Period (FY)
  2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Identification of molecules involved in the development and progression of uterine leiomyomasPrincipal Investigator
- Principal Investigator
  
  ASADA Hiromi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Long-term melatonin treatment for the prevention of ovarian aging.
- Principal Investigator
  
  TAMURA Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Search for the genes involved in the development of uterine leiomyomaPrincipal Investigator
- Principal Investigator
  
  ASADA Hiromi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
DNA methylation profile of tissue dependent and differentially methylated region in human estrogen receptor-alpha promoter regionPrincipal Investigator
- Principal Investigator
  
  ASADA Hiromi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University

All 2015 2014 2013 2012 2011 2010

All Journal Article Presentation Book

[Book] 実験医学子宮筋腫のゲノムワイドDNAメチル化プロファイル解析2010
- Author(s)
  杉野法広、前川亮、浅田裕美、山縣芳明
- Data Source
  KAKENHI-PROJECT-22791534
[Journal Article] Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice2015
- Author(s)
  Tanabe M, Tamura H, Taketani T, Okada M, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y, Sugino N.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 61 Issue: 1 Pages: 35-41
- DOI
  10.1262/jrd.2014-105
- NAID
  130004703737
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462559
[Journal Article] Importance of C/EBP β binding and histone acetylation status in the promoter regions for induction of IGFBP-1, PRL, and Mn-SOD by cAMP in human endometrial stromal cells2014
- Author(s)
  I. Tamura, S. Sato, M. Okada, M. Tanabe, L. Lee, R. Maekawa, H. Asada (他 3名)
- Journal Title
  
  Endocrinology
  
  Volume: 155 Pages: 275-286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791704
[Journal Article] Potential Mechanisms of Aberrant DNA Hypomethylation on the X Chromosome in Uterine Leiomyomas2014
- Author(s)
  S.Sato, R.Maekawa, Y.Yamagata, H.Asada (他5名)
- Journal Title
  
  J Reprod Dev
  
  Volume: 60 Pages: 47-54
- NAID
  130003381861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791704
[Journal Article] Melatonin and female reproduction2014
- Author(s)
  Tamura H, Takasaki A, Taketani T, Tanabe M, Lee L, Tamura I, Maekawa R, Aasada H, Yamagata Y, Sugino N.
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume: 40 Issue: 1 Pages: 1-11
- DOI
  10.1111/jog.12177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462559
[Journal Article] Changes in histone modification and DNA methylation of the StAR and Cyp19a1 promoter regions in granulosa cells undergoing luteinization during ovulation in female rats2013
- Author(s)
  L. lee, H. Asada (他8名)
- Journal Title
  
  Endocrinology
  
  Volume: 154 Pages: 458-470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791704
[Journal Article] Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.2013
- Author(s)
  Maekawa R, Sato S, Yamagata Y, Asada H, Tamura I, Lee L, Okada M, Tamura H, Takaki E, Nakai A, Sugino N
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 6 Pages: e66632-e66632
- DOI
  10.1371/journal.pone.0066632
- NAID
  120005652007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592471, KAKENHI-PROJECT-24790316, KAKENHI-PROJECT-24791704
[Journal Article] Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the oromoter region in human endometrial stromal cells2012
- Author(s)
  I. Tamura, H. Asada (他7名)
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 5612-5621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791704
[Journal Article] Protective role of melatonin in progesterone production by human luteal cells2011
- Author(s)
  Taketani T, Tamura H, Takasaki A, Lee L, Kizuka F, Tamura I, Taniguchi K, Maekawa R, Asada H(他3名、9番目)
- Journal Title
  
  J Pineal Res
  
  Volume: 51 Pages: 207-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791534
[Journal Article] Differential effects of progesterone on COX-2 and Mn-SOD expressions are associated with histone acetylation status of the promoter region in human endometrial stromal cells2011
- Author(s)
  Tamura I, Taketani T, Lee L, Kizuka F, Taniguchi K, Maekawa R, Asada H(他2名、7番目)
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 96 Pages: 1073-1082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791534
[Journal Article] Luteal blood flow in patients undergoing GnRH agonist long protocol2011
- Author(s)
  Takasaki A, Tamura I, Kizuka F, Lee L, Maekawa R, Asada H(他5名、6番目)
- Journal Title
  
  J Ovarian Res
  
  Volume: 4 Issue: 1 Pages: 2-2
- DOI
  10.1186/1757-2215-4-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791534
[Journal Article] Disease-dependent differently methylated regions(D-DMRs) of DNA are enriched on the X chromosome in Uterine Leiomyoma2011
- Author(s)
  Maekawa R, Yagi S, Ohgane J, Yamagata Y, Asada H(他3名、5番目)
- Journal Title
  
  J Reprod Dev
  
  Volume: 57 Pages: 604-612
- NAID
  10029878313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791534
[Journal Article] Progesterone Increases Manganese Superoxide Dismutase Expression via a cAMP-Dependent Signaling Mediated by Noncanonical Wnt5a Pathway in Human Endometrial Stromal Cells2010
- Author(s)
  Matsuoka A, Kizuka F, Lee L, Tamura I, Taniguchi K, Asada H(他3名、6番目)
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 95 Pages: 291-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791534
[Journal Article] Prostaglandin F2alpha stimulates cyclooxygenase-2 expression and prostaglandin F2alpha synthesis through NF-kB activation via reactive oxygen species in the corpus luteum of pseudopregnant rats2010
- Author(s)
  Taniguchi K, Matsuoka A, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H(他3名、7番目)
- Journal Title
  
  Reproduction
  
  Volume: 140 Pages: 885-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791534
[Presentation] Tissue-Specific expression of estrogen receptor 1　IS regulated by DNA methylation in A T-DMR （tissuedep endent and differentially methylated region）.2015
- Author(s)
  H. Asada, M.Okada, H.Tamura, N.Sugino
- Organizer
  The Annual Meeting of the American Sciety for Reproductive Medicine, ASRM2015
- Place of Presentation
  Baltimore Convention Center（USA）
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2015
- Author(s)
  田村博史、河本　舞、品川征大、岡田真紀、澁谷文恵、竹谷俊明、浅田裕美、杉野法広
- Organizer
  第33回日本受精着床学会学術総会
- Place of Presentation
  TFTホール（東京都江東区）
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2015
- Author(s)
  田村博史、河本　舞、品川征大、岡田真紀、澁谷文恵、竹谷俊明、浅田裕美、杉野法広
- Organizer
  第15回日本抗加齢医学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2014
- Author(s)
  田村博史，田邊学，岡田真紀、田村功，浅田裕美，山縣芳明，杉野法広
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2014
- Author(s)
  田村博史，田邊学，岡田真紀、田村功，浅田裕美，山縣芳明，杉野法広
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] 子宮筋腫における X 染色体の低メチル化変異機構2013
- Author(s)
  佐藤俊, 前川亮, 山縣芳明, 浅田裕美, 田村功, 李理華, 岡田真紀, 田村博史, 杉野法広
- Organizer
  第18回日本生殖内分泌学会学術集会
- Place of Presentation
  東京.シェーンバッハ・サボー
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-24791704
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2013
- Author(s)
  田村博史，田邊学，岡田真紀、田村功，浅田裕美，山縣芳明，杉野法広
- Organizer
  第31回日本受精着床学会総会学術講演会
- Place of Presentation
  別府国際コンベンションセンター（大分県）
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] 子宮筋腫のゲノムワイドDNAメチル化解析2012
- Author(s)
  前川亮、山縣芳明、田村功、李理華、浅田裕美、杉野法広
- Organizer
  第64回日本産科婦人科学会
- Place of Presentation
  神戸（神戸ポートピアホテル）
- Data Source
  KAKENHI-PROJECT-24791704
[Presentation] 卵巣子宮内膜症性嚢胞のゲノムワイドDNAメチル化プロファイル解析2012
- Author(s)
  山縣芳明、西野光一郎、田邊学、李理華、田村功、前川亮、竹谷俊明、浅田裕美、佐藤俊、田村博史、杉野法広
- Organizer
  第33回日本エンドメトリオーシス学会
- Place of Presentation
  長崎.ホテルニュー長崎.
- Year and Date
  2012-01-21
- Data Source
  KAKENHI-PROJECT-22791534
[Presentation] 子宮筋腫のゲノムワイドDNAメチル化解析2012
- Author(s)
  前川亮, 山縣芳明, 浅田裕美, 田村功, 李理華, 田邊学, 田村博史, 杉野法広
- Organizer
  第85回日本内分泌学会
- Place of Presentation
  愛知.名古屋国際会議場
- Year and Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-24791704
[Presentation] ヒト子宮内膜間質細胞(ESC)の脱落膜化によって誘導されるIGFBP-1、PRL遺伝子発現におけるepigenetic調節機構の関与2011
- Author(s)
  田村功、浅田裕美、田邊学、李理華、木塚文恵、前川亮、竹谷俊明、山縣芳明、田村博史、杉野法広
- Organizer
  第63回日本産科婦人科学会学術講演会
- Place of Presentation
  大阪.リーガロイヤルホテル大阪および大阪国際会議場
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22791534
[Presentation] ラット顆粒膜細胞の黄体化に伴うSteroidogenic Acute Regulatory(StAR)遺伝子、Cyp19a1(aromatase)遺伝子発現のepigenetics制御の関与2011
- Author(s)
  李理華、浅田裕美、田邊学、木塚文恵、田村功、前川亮、竹谷俊明、山縣芳明、田村博史、杉野法広
- Organizer
  第16回日本生殖内分泌学会
- Place of Presentation
  東京.シェーンバッハ・サボー
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-22791534
[Presentation] 子宮筋腫ではDNA低メチル化異常を呈する遺伝子がX染色体に集積する2011
- Author(s)
  前川亮、山縣芳明、浅田裕美、田村功、李理華、田邊学、竹谷俊明、田村博史、杉野法広
- Organizer
  第63回日本産科婦人科学会学術講演会
- Place of Presentation
  大阪.リーガロイヤルホテル大阪および大阪国際会議場
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22791534
[Presentation] DNA methylation and histone acethylation status in the promoter regions of IGFBP-1 and PRL in human endometrial stromal cells2011
- Author(s)
  I. Tamura, H. Asada, T. Taketani, H. Tamura, N. Sugino
- Organizer
  27th Annual meeting of the Wuropean Society of Human Reproduction and Embryology
- Place of Presentation
  ストックホルム.スウェーデン
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-22791534
[Presentation] ヒト子宮内膜間質細胞(ESC)において脱落膜化により特異的に発現するIGFBP-1遺伝子のpromoter領域のDNAメチル化とヒストンアセチル化の解析2010
- Author(s)
  田村功、木塚文恵、李理華、前川亮、浅田裕美、竹谷俊明、山縣芳明、田村博史、杉野法広
- Organizer
  第28回日本受精着床学会学術講演会
- Place of Presentation
  横浜.パシフィコ横浜
- Year and Date
  2010-07-28
- Data Source
  KAKENHI-PROJECT-22791534

1. TAMURA Hiroshi (50379947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. 佐藤俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ASADA Hiromi 浅田 裕美

Research Projects

Research Products

Co-Researchers

MED12遺伝子の突然変異の有無による子宮筋腫発生機序の違いの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of molecules involved in the development and progression of uterine leiomyomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Long-term melatonin treatment for the prevention of ovarian aging.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for the genes involved in the development of uterine leiomyomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

DNA methylation profile of tissue dependent and differentially methylated region in human estrogen receptor-alpha promoter regionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 実験医学子宮筋腫のゲノムワイドDNAメチル化プロファイル解析2010

Author(s)

Data Source

[Journal Article] Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Importance of C/EBP β binding and histone acetylation status in the promoter regions for induction of IGFBP-1, PRL, and Mn-SOD by cAMP in human endometrial stromal cells2014

Author(s)

Journal Title

Data Source

[Journal Article] Potential Mechanisms of Aberrant DNA Hypomethylation on the X Chromosome in Uterine Leiomyomas2014

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Melatonin and female reproduction2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in histone modification and DNA methylation of the StAR and Cyp19a1 promoter regions in granulosa cells undergoing luteinization during ovulation in female rats2013

Author(s)

Journal Title

Data Source

[Journal Article] Genome-wide DNA methylation analysis reveals a potential mechanism for the pathogenesis and development of uterine leiomyomas.2013

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Induction of IGFBP-1 expression by cAMP is associated with histone acetylation status of the oromoter region in human endometrial stromal cells2012

Author(s)

Journal Title

Data Source

[Journal Article] Protective role of melatonin in progesterone production by human luteal cells2011

Author(s)

Journal Title

Data Source

[Journal Article] Differential effects of progesterone on COX-2 and Mn-SOD expressions are associated with histone acetylation status of the promoter region in human endometrial stromal cells2011

Author(s)

Journal Title

ASADA Hiromi 浅田裕美

[Presentation] Tissue-Specific expression of estrogen receptor 1　IS regulated by DNA methylation in A T-DMR （tissuedep endent and differentially methylated region）.2015