Masugi Yohei 眞杉洋平

… Alternative Names

MASUGI Yohei 眞杉洋平

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Researcher Number	90528598
Other IDs
Affiliation (Current)	2025: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 東海大学, 医学部, 教授 2018 – 2024: 慶應義塾大学, 医学部(信濃町), 講師 2012 – 2014: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / Human pathology Except Principal Investigator Basic Section 49020:Human pathology-related
Keywords	Principal Investigator 膵がん / 膵癌 / 免疫抑制 / 画像解析 / 腫瘍内不均一 / 間質療法 / 腫瘍免疫 / 腫瘍微小環境 / 免疫療法 / 人体病理学 … More / 不均一 / 線維芽細胞亜型 / 免疫 / Ｔリンパ球 / 腫瘍不均一 / 間質標的治療 / ITGB4 / SMAD3 / マイクロアレイ / 予後 / 上皮間葉移行 / 弧在性浸潤 … More Except Principal Investigator 多重蛍光染色 / 分子病理疫学 / ヒト / 疫学コホート / 腫瘍免疫 / 膵癌 Less

膵癌の分子病理学的多様性に由来する特異的糖鎖変化の同定、液状検体診断への応用Principal Investigator
- Principal Investigator
  
  眞杉洋平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tokai University
ヒト膵癌の免疫微小環境の超多重染色と大規模コホート解析による新規治療戦略の確立
- Principal Investigator
  
  濱田毅
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  The University of Tokyo
Heterogeneity of the desmoplastic stroma of human pancreatic cancer: Clinicopathological significance and molecular chanisms shaping the heterogeneityPrincipal Investigator
- Principal Investigator
  
  Masugi Yohei
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Keio University
Image analysis-based subtyping of immunosuppressive tumor-immune microenvironment in pancreatic cancer tissuePrincipal Investigator
- Principal Investigator
  
  Masugi Yohei
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Keio University
Molecular mechanism of solitary cell infiltration in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  MASUGI Yohei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  Keio University

All 2024 2023 2022 2021 2020 2019 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] 膵癌における癌関連線維芽細胞の多様性2024
- Author(s)
  眞杉　洋平
- Journal Title
  
  肝胆膵
  
  Volume: 88
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] Post-operative mortality and recurrence patterns in pancreatic cancer according to KRAS mutation and CDKN2A, p53, and SMAD4 expression.2023
- Author(s)
  Masugi Y, Takamatsu M, Tanaka M(Co-first author), Hara K, Inoue Y, Hamada T, Suzuki T, Arita J, Hirose Y, Kawaguchi Y, Nakai Y, Oba A, Sasahira N, Shimane G, Takeda T, Tateishi K, Uemura S, Fujishiro M, Hasegawa K, Kitago M, Takahashi Y, Ushiku T, Takeuchi K, Sakamoto M; GTK Pancreatic Cancer Study Group in Japan.
- Journal Title
  
  J Pathol Clin Res.
  
  Volume: 9 Issue: 5 Pages: 339-353
- DOI
  10.1002/cjp2.323
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06976, KAKENHI-PROJECT-20K07414
[Journal Article] Pancreatic cancer stromal heterogeneity characterized by multiplex immunohistochemistry-based image analyses2023
- Author(s)
  MASUGI Yohei
- Journal Title
  
  Suizo
  
  Volume: 38 Issue: 1 Pages: 28-36
- DOI
  10.2958/suizo.38.28
- ISSN
  0913-0071, 1881-2805
- Year and Date
  2023-02-28
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] 【膵臓の発生・生理・解剖から膵炎・膵癌の病態解明に至る最新の知見】膵癌組織イメージングにより見出された3種類の膵癌間質タイプ2022
- Author(s)
  眞杉　洋平
- Journal Title
  
  胆と膵
  
  Volume: 43 Pages: 801-807
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] 膵癌の診断・治療の近未来.(座談会)2022
- Author(s)
  坂元亨宇, 眞杉洋平, 波多野悦朗, 正宗淳.
- Journal Title
  
  肝胆膵
  
  Volume: 84 Pages: 245-255
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] Three Distinct Stroma Types in Human Pancreatic Cancer Identified by Image Analysis of Fibroblast Subpopulations and Collagen-Response2022
- Author(s)
  Y. Masugi, T. Abe, K. Yamazaki, A. Ueno, M Sakamoto
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 28 Issue: 2 Pages: 427-427
- DOI
  10.1158/1078-0432.ccr-21-3693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] 【膵癌診療のパラダイムシフト】膵癌研究における最近の知見　膵癌における線維性間質、線維芽細胞サブタイプの意義2022
- Author(s)
  眞杉　洋平
- Journal Title
  
  肝胆膵
  
  Volume: 84 Pages: 239-244
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] KRAS variant allele frequency, but not mutation positivity, associates with survival of patients with pancreatic cancer2022
- Author(s)
  Suzuki T, Masugi Y, Inoue Y, Hamada T, Tanaka M, Takamatsu M, Arita J, Kato T, Kawaguchi Y, Kunita A, Nakai Y, Nakano Y, Ono Y, Sasahira N, Takeda T, Tateishi K, Uemura S, Koike K, Ushiku T, Takeuchi K, Sakamoto M, Hasegawa K, Kitago M, Takahashi Y, Fujishiro M.
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 9 Pages: 3097-3109
- DOI
  10.1111/cas.15398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08362, KAKENHI-PROJECT-20K07414, KAKENHI-PROJECT-21K07886, KAKENHI-PROJECT-22K06976, KAKENHI-PROJECT-20K07422
[Journal Article] Three Distinct Stroma Types in Human Pancreatic Cancer Identified by Image Analysis of Fibroblast Subpopulations and Collagen.2021
- Author(s)
  Ogawa Y., Masugi Y., Abe T., Yamazaki K., Ueno A., Fujii-Nishimura Y., Hori S., Yagi H., Abe Y., Kitago M., Sakamoto M.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 27 Issue: 1 Pages: 107-119
- DOI
  10.1158/1078-0432.ccr-20-2298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07414
[Journal Article] Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis2020
- Author(s)
  Fujita, Y. Matsuda, S. Sasaki, Y. Masugi, Y. Kitago, M. Yagi, H. Abe, Y. Shinoda, M. Tokino, T. Sakamoto, M. Kitagawa, Y.
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Issue: 2 Pages: 739-748
- DOI
  10.1111/cas.14268
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09354, KAKENHI-PROJECT-19K07645, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-18K15094, KAKENHI-PROJECT-16H06279
[Journal Article] Characterization of spatial distribution of tumor-infiltrating CD8(+) T cells refines their prognostic utility for pancreatic cancer survival2019
- Author(s)
  Masugi Y, Abe T, Ueno A, Fujii-Nishimura Y, Ojima H, Endo Y, Fujita Y, Kitago M, Shinoda M, Kitagawa Y, Sakamoto M
- Journal Title
  
  Modern Pathology
  
  Volume: 32 Issue: 10 Pages: 1495-1507
- DOI
  10.1038/s41379-019-0291-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15094
[Journal Article] Upregulation of integrin beta4 promotes epithelial-mesenchymal transition and is a novel prognostic marker in pancreatic ductal adenocarcinoma2015
- Author(s)
  Masugi Y, Yamazaki K, Emoto K, Effendi K, Tsujikawa H, Kitago M, Itano O, Kitagawa Y, Sakamoto M
- Journal Title
  
  Labolatory Investigation
  
  Volume: 95 Issue: 3 Pages: 308-19
- DOI
  10.1038/labinvest.2014.166
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24790362
[Journal Article] Upregulated SMAD3 promotes epithelial-mesenchymal transition and predicts poor prognosis in pancreatic ductal adenocarcinoma2014
- Author(s)
  Yamazaki K, Masugi Y, Effendi K, Tsujikawa H, Hiraoka N, Kitago M, Shinoda M, Itano O, Tanabe M, Kitagawa Y, Sakamoto M
- Journal Title
  
  Laboratory investigation
  
  Volume: 印刷中 Issue: 4 Pages: 817-25
- DOI
  10.1016/j.humpath.2013.11.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790362, KAKENHI-PROJECT-26860246
[Presentation] Heterogeneity of the pancreatic cancer microenvironment.2023
- Author(s)
  Masugi Y
- Organizer
  35th European Congress of Pathology, Special Session (Dublin, Ireland)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07414
[Presentation] Droplet digital PCR for KRAS mutations in pancreatic cancer: An analysis of clinical samples in a multicenter cohort.2022
- Author(s)
  鈴木辰典, 眞杉洋平, 高松学, 濱田毅, 田中麻理子, 国田朱子, 中野容, 立石敬介, 小池和彦, 牛久哲男, 坂元亨宇, 竹内賢吾, 北郷実, 藤城光弘.
- Organizer
  第81回日本癌学会学術集会　臓器別シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07414
[Presentation] 膵管癌の悪性度を規定する特徴的病理像に係る分子病理基盤の解析2022
- Author(s)
  眞杉洋平
- Organizer
  第68回日本病理学会秋季特別総会学術研究賞演説
- Invited
- Data Source
  KAKENHI-PROJECT-20K07414
[Presentation] Pancreatic cancer subtypes according to immune/stromal heterogeneity: real-world data from pathology imaging informatics.2021
- Author(s)
  眞杉洋平, 阿部時也, 山崎剣, 上野彰久, 西村瑶子, 北郷実, 坂元亨宇
- Organizer
  第80回日本癌学会総会　臓器別シンポジウム２　肝胆膵がんにおける基礎および臨床研究の進展
- Data Source
  KAKENHI-PROJECT-20K07414
[Presentation] 膵癌組織イメージングによる線維芽細胞亜型の同定：間質多様性の意義に係る新知見2021
- Author(s)
  眞杉洋平, 北郷実
- Organizer
  第52回日本膵臓学会　ワークショップ２　臨床研究の基盤になる膵臓の発生、解剖、生理、病理の新知見
- Data Source
  KAKENHI-PROJECT-20K07414
[Presentation] 線維芽細胞亜型とコラーゲン量により規定される膵がん間質3タイプの分子病理学的特徴2021
- Author(s)
  眞杉洋平、阿部時也、山崎剣、上野彰久、西村瑶子、坂元亨宇
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K07414
[Presentation] Characterization of tumor heterogeneity in pancreatic cancer desmoplastic stroma by multiplex immunohistochemistry-based image analysis2020
- Author(s)
  Masugi Y, Abe T, Ogawa Y, Sakamoto M
- Organizer
  USCAP annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] CD8+ cell density in the tumor center relates to pancreatic cancer survival differentially by the abundance of CD8+ cell infiltrates in the tumor margin2019
- Author(s)
  Masugi Y, Abe T, Kitago M, Shinoda M, Sakamoto M
- Organizer
  American Pancreatic Association Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] ヒト膵癌組織に浸潤する細胞傷害性T細胞の空間的定量画像解析2019
- Author(s)
  眞杉洋平
- Organizer
  第一回日本医学会連合Rising Starリトリート
- Invited
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] 多発膵管癌の二つの異なる発生経路に関する分子病理学的解析2019
- Author(s)
  眞杉洋平, 藤田優裕, 北郷実, 北川雄光
- Organizer
  第50回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] Characterization of spatial distribution of tumor-infiltrating CD8+ T cells refines their prognostic impact in pancreatic cancer2019
- Author(s)
  Masugi Y, Abe T, Kitago M, Shinoda M, Sakamoto M
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] Prognostic value of CD8+ T-cell density computed by quantitative image analysis using whole tissue sections of pancreatic ductal adenocarcinoma2019
- Author(s)
  Yohei Masugi, Tokiya Abe, Minoru Kitago, Masahiro Shinoda, Michiie Sakamoto
- Organizer
  AACR Special Conference on Pancreatic Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] 膵癌組織におけるCD8陽性T細胞浸潤の空間分布・密度解析は精緻な予後予測に有用である2019
- Author(s)
  眞杉洋平、阿部時也、西村瑤子、上野彰久、久保田直人、川井田みほ、辻川華子、尾島英知、坂元亨宇
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] 膵癌組織におけるCD8陽性T細胞浸潤の空間分布・密度解析は精緻な予後予測に有用である2019
- Author(s)
  眞杉洋平, 阿部時也, 西村瑶子, 久保田直人, 上野彰久, 川井田みほ, 辻川華子, 尾島英知, 坂元亨宇
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] Characterization of spatial distribution of tumor-infiltrating CD8+ T cells refines their prognostic impact in pancreatic cancer2019
- Author(s)
  Yohei Masugi, Tokiya Abe, Minoru Kitago, Masahiro Shinoda, Michiie Sakamoto
- Organizer
  American Association for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15094
[Presentation] Up-regulation of integrin beta 4 promotes epithelial-mesenchymal transition and is a novel prognostic marker in pancreatic cancer2014
- Author(s)
  Yohei Masugi, Ken Yamazaki, Katsura Emoto, Kathryn Effendi, Hanako Tsujikawa, Minoru Kitago, Osamu Itano, Yuko Kitagawa, Michiie Sakamoto
- Organizer
  American Association for Cancer Research annual meeting 2014
- Place of Presentation
  サンディエゴ（アメリカ）
- Data Source
  KAKENHI-PROJECT-24790362
[Presentation] SMAD3 upregulation is a novel biomarker of poor prognosis and epithelial-mesenchymal transition in pancreatic cancer2013
- Author(s)
  Ken Yamazaki, Yohei Masugi, Kathryn Effendi, Michiie Sakamoto.
- Organizer
  American Association of Cancer Research annual meeting 2013
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-24790362
[Presentation] SMAD3 upregulation is a novel biomarker of poor prognosis and epithelial-mesenchymal transition in pancreatic cancer2013
- Author(s)
  Ken Yamazaki, Yohei Masugi, Kathryn Effendi, Michiie Sakamoto
- Organizer
  American Association for Cancer Research annual meeting 2013
- Place of Presentation
  ワシントンDC（アメリカ）
- Data Source
  KAKENHI-PROJECT-24790362
[Presentation] Up-regulation of integrin beta 4 promotes epithelial-mesenchymal transition and is a novel prognostic marker in pancreatic cancer.
- Author(s)
  Masugi Y, Yamazaki K, Emoto K, Effendi K, Kitago M, Itano O, Kitagawa Y, Sakamoto M.
- Organizer
  American Association of Cancer Research Annual meeting
- Place of Presentation
  San Diego Convention Center (San Diego, USA)
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24790362

1. 濱田毅 (90723461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 中村正裕 (40634449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TATEISHI Keisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 田中麻理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 佐々木泰史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 中井陽介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Masugi Yohei 眞杉 洋平

MASUGI Yohei 眞杉 洋平

Research Projects

Research Products

Co-Researchers

膵癌の分子病理学的多様性に由来する特異的糖鎖変化の同定、液状検体診断への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒト膵癌の免疫微小環境の超多重染色と大規模コホート解析による新規治療戦略の確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Heterogeneity of the desmoplastic stroma of human pancreatic cancer: Clinicopathological significance and molecular chanisms shaping the heterogeneityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Image analysis-based subtyping of immunosuppressive tumor-immune microenvironment in pancreatic cancer tissuePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of solitary cell infiltration in pancreatic cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 膵癌における癌関連線維芽細胞の多様性2024

Author(s)

Journal Title

Data Source

[Journal Article] Post-operative mortality and recurrence patterns in pancreatic cancer according to KRAS mutation and CDKN2A, p53, and SMAD4 expression.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pancreatic cancer stromal heterogeneity characterized by multiplex immunohistochemistry-based image analyses2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] 【膵臓の発生・生理・解剖から膵炎・膵癌の病態解明に至る最新の知見】膵癌組織イメージングにより見出された3種類の膵癌間質タイプ2022

Author(s)

Journal Title

Data Source

[Journal Article] 膵癌の診断・治療の近未来.(座談会)2022

Author(s)

Journal Title

Data Source

[Journal Article] Three Distinct Stroma Types in Human Pancreatic Cancer Identified by Image Analysis of Fibroblast Subpopulations and Collagen-Response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 【膵癌診療のパラダイムシフト】膵癌研究における最近の知見 膵癌における線維性間質、線維芽細胞サブタイプの意義2022

Author(s)

Journal Title

Data Source

[Journal Article] KRAS variant allele frequency, but not mutation positivity, associates with survival of patients with pancreatic cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three Distinct Stroma Types in Human Pancreatic Cancer Identified by Image Analysis of Fibroblast Subpopulations and Collagen.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathogenesis of multiple pancreatic cancers involves multicentric carcinogenesis and intrapancreatic metastasis2020

Masugi Yohei 眞杉洋平

MASUGI Yohei 眞杉洋平

[Journal Article] 【膵癌診療のパラダイムシフト】膵癌研究における最近の知見　膵癌における線維性間質、線維芽細胞サブタイプの意義2022