Matsui Takeshi 松井健

… Alternative Names

松井健マツイタケシ

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Researcher Number	90528605
Other IDs	https://orcid.org/0000-0002-1678-284X
Affiliation (Current)	2025: 関西医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2022: 島根大学, 学術研究院医学・看護学系, 特任講師 2019 – 2020: 奈良県立医科大学, 医学部, 助教 2013: 慶應義塾大学, 医学部, 助教 2010: Keio University, 医学部, 研究員 2009: Keio University, 医学部, 研究員(非常勤)
Review Section/Research Field	Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 51030:Pathophysiologic neuroscience-related / Neurophysiology / General neuroscience / General physiology Except Principal Investigator Basic Section 63020:Radiation influence-related / Basic Section 52020:Neurology-related
Keywords	Principal Investigator ヒト脳オルガノイド / オルガノイド / 血管 / 再生医療 / ミクログリア / 神経 / 発生 / 幹細胞 / 神経発生 / 人工多能性幹細胞 / 実験動物 … More Except Principal Investigator … More 脳オルガノイド / DNA修復欠損 / 色素性乾皮症 / 修復欠損 / 酸化的DNA損傷 / サイクロプリン / 神経障害 / RAN翻訳 / リピート病 / オルガノイド / laser micro-irradiation / ポリペプチド / 脊髄小脳変性症 / 脳幹オルガノイド / DNA修復 / 核内封入体病 / ALS / RAN translation / C9orf72 / FUS / 筋萎縮性側索硬化症 / 非翻訳領域リピート病 / 神経変性疾患 Less

Human organoid-based research on the regulation of neural development by vascular systemsPrincipal Investigator
- Principal Investigator
  
  松井健
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Shimane University
Mechanism analyses of progressive neurological diseases in xeroderma pigmentosum group A patients using their iPSCs-derived cerebral organoids
- Principal Investigator
  
  Mori Toshio
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Nara Medical University
Pathophysiological analysis of repeat disease causing neurodegenerative disease using human brain organoids.
- Principal Investigator
  
  Kiriyama Takao
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nara Medical University
The research in the human brain development by the use of microglia-containing human brain organoidsPrincipal Investigator
- Principal Investigator
  
  Matsui Takeshi
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Shimane University
  Nara Medical University
成体ヒト線維芽細胞を用いて迅速かつ高効率に神経幹細胞を誘導する直接誘導法の確立Principal Investigator
- Principal Investigator
  
  松井健
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Keio University
ヒト細胞の再生医療における移植源としての有用性を評価する新規動物システムの確立Principal Investigator
- Principal Investigator
  
  松井健
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Keio University

All 2021 2020 2019

All Journal Article Presentation

[Journal Article] Gene expression profiles of human cerebral organoids identify PPAR pathway and PKM2 as key markers for oxygen-glucose deprivation and reoxygenation2021
- Author(s)
  Naoki Iwasa, Takeshi K. Matsui, Naohiko Iguchi, Kaoru Kinugawa, Naritaka Morikawa, Yoshihiko M. Sakaguchi, Tomo Shiota, Shinko Kobashigawa et. al.
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: － Pages: 605030-605030
- DOI
  10.3389/fncel.2021.605030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23952, KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-21K06758, KAKENHI-PROJECT-21K18273, KAKENHI-PROJECT-20H03680, KAKENHI-PROJECT-19K08150
[Journal Article] Brainstem organoids from human pluripotent stem cells2020
- Author(s)
  Nobuyuki Eura, Takeshi K. Matsui, Joachim Luginbuhl, Masaya Matsubayashi, Hitoki Nanaura, Tomo Shiota, Kaoru Kinugawa, Naohiko Iguchi, Takao Kiriyama, Canbin Zheng, Tsukasa Kouno, Yan Jun Lan, Pornparn Kongpracha, Pattama Wiriyasermkul, Yoshihiko M. Sakaguchi, Riko Nagata, Tomoya Komeda, Naritaka Morikawa, et al.
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: - Pages: 00538-00538
- DOI
  10.3389/fnins.2020.00538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23952, KAKENHI-PROJECT-19K21306, KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K08150, KAKENHI-PROJECT-20K16583, KAKENHI-PROJECT-20K16606, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-18K06524, KAKENHI-PROJECT-19K16925, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02770
[Journal Article] Challenges in Modeling Human Neural Circuit Formation via Brain Organoid Technology2020
- Author(s)
  Matsui TK, Tsuru Y, Kuwako KI
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 14 Pages: 607399-607399
- DOI
  10.3389/fncel.2020.607399
- NAID
  120007002189
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22476, KAKENHI-PROJECT-20H03352, KAKENHI-PROJECT-19K16925
[Presentation] Rapid induction of midbrain-like organoids from human pluripotent stem cells2019
- Author(s)
  Hitoki Nanaura, Takeshi K. Matsui, Tomo Shiota, Nobuyuki Eura, Eiichiro Mori, Kazuma Sugie
- Organizer
  日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K16925
[Presentation] Human cerebral organoids recapitulate brain formation and genetic developmental disorders2019
- Author(s)
  Takeshi K. Matsui, Nobuyuki Eura, Hitoki Nanaura, Tomo Shiota, Eiichiro Mori, Kazuma Sugie
- Organizer
  日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K16925
[Presentation] Recapitulation of brain ischemia with human cerebral organoids2019
- Author(s)
  Tomo Shiota, Takeshi K. Matsui, Nobuyuki Eura, Hitoki Nanaura, Eiichiro Mori, Kazuma Sugie,
- Organizer
  日本神経学会総会
- Data Source
  KAKENHI-PROJECT-19K16925

1. Kiriyama Takao (80571025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. Mori Toshio (10115280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 杉江和馬 (60347549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 七浦仁紀 (00827909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 塩田智 (70837062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 井口直彦 (50838232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 森英一朗 (70803659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 桑子賢一郎 (30468475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 絹川薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Matsui Takeshi 松井 健

松井 健 マツイ タケシ

Research Projects

Research Products

Co-Researchers

Human organoid-based research on the regulation of neural development by vascular systemsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism analyses of progressive neurological diseases in xeroderma pigmentosum group A patients using their iPSCs-derived cerebral organoids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological analysis of repeat disease causing neurodegenerative disease using human brain organoids.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The research in the human brain development by the use of microglia-containing human brain organoidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

成体ヒト線維芽細胞を用いて迅速かつ高効率に神経幹細胞を誘導する直接誘導法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト細胞の再生医療における移植源としての有用性を評価する新規動物システムの確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gene expression profiles of human cerebral organoids identify PPAR pathway and PKM2 as key markers for oxygen-glucose deprivation and reoxygenation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brainstem organoids from human pluripotent stem cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Challenges in Modeling Human Neural Circuit Formation via Brain Organoid Technology2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Rapid induction of midbrain-like organoids from human pluripotent stem cells2019

Author(s)

Organizer

Data Source

[Presentation] Human cerebral organoids recapitulate brain formation and genetic developmental disorders2019

Author(s)

Organizer

Data Source

[Presentation] Recapitulation of brain ischemia with human cerebral organoids2019

Author(s)

Organizer

Data Source

Matsui Takeshi 松井健

松井健マツイタケシ