Honda Shinya 本田真也

… Alternative Names

HONDA Shinya 本田真也

Less

Researcher Number	90532672
Other IDs
Affiliation (Current)	2025: 東京科学大学, 総合研究院, プロジェクト准教授
Affiliation (based on the past Project Information) *help	2023: 東京医科歯科大学, 難治疾患研究所, 講師 2019 – 2022: 東京医科歯科大学, 難治疾患研究所, プロジェクト講師 2015 – 2018: 東京医科歯科大学, 難治疾患研究所, 助教 2009 – 2010: National Center of Neurology and Psychiatry, 神経研究所疾病研究第一部, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 54010:Hematology and medical oncology-related / Pathological medical chemistry / General medical chemistry / Neurology
Keywords	Principal Investigator オートファジー / 中心体 / がん / 赤血球 / 神経変性疾患 / 病理学 / 筋疾患 / 筋病理

新規オートファジーによるタウオパチー制御機構の解明Principal Investigator
- Principal Investigator
  
  本田真也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Tokyo Medical and Dental University
An analysis of mechanism of mitochondria clearance by alternative autophagy during erythrocyte differentiationPrincipal Investigator
- Principal Investigator
  
  Honda Shinya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokyo Medical and Dental University
Analysis of tumorigenesis by autophagy failure and centrosomal dysregulation.Principal Investigator
- Principal Investigator
  
  HONDA Shinya
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
An analysis of the mechanism of the alternative autophagyPrincipal Investigator
- Principal Investigator
  
  Honda Shinya
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tokyo Medical and Dental University
An analysis of molecular mechanism of XMEAPrincipal Investigator
- Principal Investigator
  
  HONDA Shinya
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurology
- Research Institution
  National Center of Neurology and Psychiatry

All 2024 2023 2020 2019 2018 2017 2016 2015 2010

All Journal Article Presentation

[Journal Article] Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes2024
- Author(s)
  Hasegawa Tatsuya、Noguchi Saori、Nakashima Masaya、Miyai Masashi、Goto Makiko、Matsumoto Yuko、Torii Satoru、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 4 Pages: 107173-107173
- DOI
  10.1016/j.jbc.2024.107173
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07345
[Journal Article] Subcellular localization and ER-mediated cytotoxic function of α1A and α1ACT in spinocerebellar ataxia type 62024
- Author(s)
  Wang Di、Honda Shinya、Shin Min Kyoung、Watase Kei、Mizusawa Hidehiro、Ishikawa Kinya、Shimizu Shigeomi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 695 Pages: 149481-149481
- DOI
  10.1016/j.bbrc.2024.149481
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07345, KAKENHI-PROJECT-23K06960, KAKENHI-PROJECT-21K07432
[Journal Article] An Overview of Golgi Membrane-Associated Degradation (GOMED) and Its Detection Methods2023
- Author(s)
  Sakurai Hajime Tajima、Arakawa Satoko、Yamaguchi Hirofumi、Torii Satoru、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Cells
  
  Volume: 12 Issue: 24 Pages: 2817-2817
- DOI
  10.3390/cells12242817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06909, KAKENHI-PROJECT-22K07345, KAKENHI-PROJECT-23K05748
[Journal Article] Absence of ULK1 decreases AMPK activity in the kidney, leading to chronic kidney disease progression2023
- Author(s)
  Tomoki Yanagi, Hiroaki Kikuchi, Koichiro Susa, Naohiro Takahashi, Naohiro Takahashi, Hiroki Bamba, Takefumi Suzuki, Yuta Nakano, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Shintaro Mandai, Takayasu Mori, Koh Takeuchi, Shinya Honda, Satoru Torii, Shigeomi Shimizu, Tatemitsu Rai, Shinichi Uchida, Eisei Sohara
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 1 Pages: 5-14
- DOI
  10.1111/gtc.12989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08223, KAKENHI-PROJECT-21K08249, KAKENHI-PROJECT-22K07345, KAKENHI-PROJECT-22K19518, KAKENHI-PROJECT-20H00467, KAKENHI-PROJECT-21K20710, KAKENHI-WRAPUP-22H04899, KAKENHI-PROJECT-23K19610, KAKENHI-PUBLICLY-22H04639, KAKENHI-PROJECT-20H03378
[Journal Article] Association Between Atg5-independent Alternative Autophagy and Neurodegenerative Diseases.2020
- Author(s)
  Honda S, Arakawa S, Yamaguchi H, Torii S, Tajima Sakurai H, Tsujioka M, Murohashi M, Shimizu S.
- Journal Title
  
  Journal of molecular biology
  
  Volume: 432 Issue: 8 Pages: 2622-2632
- DOI
  10.1016/j.jmb.2020.01.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K08859, KAKENHI-PROJECT-19K16119, KAKENHI-PROJECT-19K07382, KAKENHI-PROJECT-20K07353, KAKENHI-PUBLICLY-20H05314
[Journal Article] Autophagy involvement in oncogenesis2020
- Author(s)
  Torii Satoru、Honda Shinya、Murohashi Michiko、Yamaguchi Hirofumi、Shimizu Shigeomi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 11 Pages: 3993-3999
- DOI
  10.1111/cas.14646
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07382, KAKENHI-PROJECT-19K08859, KAKENHI-PROJECT-18K06210
[Journal Article] Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration2020
- Author(s)
  Yamaguchi Hirofumi、Honda Shinya、Torii Satoru、Shimizu Kimiko、Katoh Kaoru、Miyake Koichi、Miyake Noriko、Fujikake Nobuhiro、Sakurai Hajime Tajima、Arakawa Satoko、Shimizu Shigeomi
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5311-5311
- DOI
  10.1038/s41467-020-18892-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07382, KAKENHI-PROJECT-19K08859, KAKENHI-PROJECT-20K07353, KAKENHI-PUBLICLY-20H05314, KAKENHI-PROJECT-18K06210, KAKENHI-PROJECT-19K16119, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
[Journal Article] Prediction of intracellular targets of a small compound by analyzing peptides presented on MHC class I2019
- Author(s)
  Sugimoto Yuna、Murohashi Michiko、Arakawa Satoko、Honda Shinya、Shimizu Shigeomi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Issue: 2 Pages: 480-486
- DOI
  10.1016/j.bbrc.2018.11.089
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K15613
[Journal Article] Beclin 1 regulates recycling endosome and is required for skin development in mice2019
- Author(s)
  Noguchi Saori、Honda Shinya、Saitoh Tatsuya、Matsumura Hiroyuki、Nishimura Emi、Akira Shizuo、Shimizu Shigeomi
- Journal Title
  
  Communications Biology
  
  Volume: 2 Issue: 1 Pages: 37-37
- DOI
  10.1038/s42003-018-0279-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KK0229, KAKENHI-PUBLICLY-17H05614, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-17H06415, KAKENHI-PROJECT-17H01533, KAKENHI-PROJECT-17K19514, KAKENHI-PROJECT-17K15613, KAKENHI-PROJECT-18H02637, KAKENHI-PLANNED-26115003, KAKENHI-PROJECT-26221303
[Journal Article] Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy2017
- Author(s)
  Arakawa S, Honda S, Yamaguchi H, Shimizu S.
- Journal Title
  
  Proceedings of the Japan Academy, Series B
  
  Volume: 93 Issue: 6 Pages: 378-385
- DOI
  10.2183/pjab.93.023
- NAID
  130005696809
- ISSN
  0386-2208, 1349-2896
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15613, KAKENHI-PUBLICLY-17H05691, KAKENHI-PLANNED-26110005
[Journal Article] Monitoring of Atg5-Independent Mitophagy2017
- Author(s)
  Arakawa Satoko、Honda Shinya、Torii Satoru、Tsujioka Masatsune、Shimizu Shigeomi
- Journal Title
  
  Methods Mol Biol.
  
  Volume: - Pages: 125-132
- DOI
  10.1007/7651_2017_16
- ISBN
  9781493977499, 9781493977505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15613, KAKENHI-PLANNED-26110005
[Journal Article] Autophagy controls centrosome number.2017
- Author(s)
  Honda S, Shimizu S
- Journal Title
  
  Oncotarget
  
  Volume: 8 Issue: 9 Pages: 14277-14278
- DOI
  10.18632/oncotarget.15362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-17K15613
[Journal Article] Identification of PPM1D as an essential Ulk1 phosphatase for genotoxic stress-induced autophagy.2016
- Author(s)
  Torii S, Yoshida T, Arakawa S, Honda S, Nakanishi A, Shimizu S.
- Journal Title
  
  EMBO Rep.
  
  Volume: 17 Pages: 1552-1564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19004
[Journal Article] Autophagy suppresses cell migration by degrading GEF-H1, a RhoA GEF2016
- Author(s)
  T. Yoshida, M. Tsujioka, S. Honda, S. Shimizu
- Journal Title
  
  Oncotarget
  
  Volume: 7 Issue: 23 Pages: 34420-9
- DOI
  10.18632/oncotarget.8883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110006, KAKENHI-PROJECT-26293089, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-16K15230
[Journal Article] Autophagy controls centrosome number by degrading Cep63.2016
- Author(s)
  Watanabe Y, Honda S, Konishi A, Satoko Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13508-13508
- DOI
  10.1038/ncomms13508
- NAID
  120007129257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-26430051, KAKENHI-PROJECT-26460485, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] 筋疾患とオートファジー2010
- Author(s)
  本田真也, 西野一三
- Journal Title
  
  BIO Clinica. 25
  
  Pages: 42-46
- Data Source
  KAKENHI-PROJECT-21890313
[Presentation] GOMED関連分子の探索及び同定分子の解析2023
- Author(s)
  本田　真也
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K07345
[Presentation] オートファジーは中心体数を制御することで腫瘍形成を抑制する2018
- Author(s)
  本田真也、清水重臣
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K15613
[Presentation] オートファジーは中心体数を制御することで腫瘍形成を抑制する2017
- Author(s)
  本田真也・清水重臣
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K15613
[Presentation] オートファジーによる中心体蛋白質Cep63の分解を介した中心体数の制御2017
- Author(s)
  本田真也
- Organizer
  細胞競合・ダイイングコード若手合同会議
- Place of Presentation
  ホテルコスモスクエア国際交流センター（大阪府）
- Year and Date
  2017-01-17
- Data Source
  KAKENHI-PROJECT-15K19004
[Presentation] オートファジーによる中心体タンパク質Cep63の分解を介した中心体数の制御2016
- Author(s)
  本田真也
- Organizer
  第10回オートファジー研究会
- Place of Presentation
  NASPAニューオータニ（新潟県）
- Year and Date
  2016-11-14
- Data Source
  KAKENHI-PROJECT-15K19004
[Presentation] オートファジーによるCep63の分解を介した中心体数の制御2016
- Author(s)
  本田真也、渡辺雄一郎、小西昭充、室橋道子、荒川聡子、山口啓史、清水重臣
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K19004
[Presentation] 赤血球成熟段階のミトコンドリア除去における新規オートファジーの役割2016
- Author(s)
  本田真也
- Organizer
  酸素生物学・ダイイングコード合同若手会議
- Place of Presentation
  一の宮シーサイドオーツカ (千葉県)
- Year and Date
  2016-01-26
- Data Source
  KAKENHI-PROJECT-15K19004
[Presentation] 赤血球成熟段階のミトコンドリア除去における新規オートファジーの役割2015
- Author(s)
  本田真也
- Organizer
  第９回オートファジー研究会・第３回新学術「オートファジー」班会議
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路島）
- Year and Date
  2015-11-15
- Data Source
  KAKENHI-PROJECT-15K19004
[Presentation] XMEAの分子病態の解析2010
- Author(s)
  本田真也
- Organizer
  第33回日本分子生物学会第83回日本生化学会合同大会
- Place of Presentation
  神戸・神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21890313
[Presentation] XMEAの分子病態の解析2010
- Author(s)
  本田真也
- Organizer
  第33回日本分子生物学会大会第83回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21890313

1. TORII Satoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. SAITOH Tatsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山口啓史

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. 清水重臣

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 須佐紘一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Honda Shinya 本田 真也

HONDA Shinya 本田 真也

Research Projects

Research Products

Co-Researchers

新規オートファジーによるタウオパチー制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An analysis of mechanism of mitochondria clearance by alternative autophagy during erythrocyte differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of tumorigenesis by autophagy failure and centrosomal dysregulation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An analysis of the mechanism of the alternative autophagyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An analysis of molecular mechanism of XMEAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Alternative autophagy dampens UVB-induced NLRP3 inflammasome activation in human keratinocytes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Subcellular localization and ER-mediated cytotoxic function of α1A and α1ACT in spinocerebellar ataxia type 62024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Overview of Golgi Membrane-Associated Degradation (GOMED) and Its Detection Methods2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Absence of ULK1 decreases AMPK activity in the kidney, leading to chronic kidney disease progression2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association Between Atg5-independent Alternative Autophagy and Neurodegenerative Diseases.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autophagy involvement in oncogenesis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of intracellular targets of a small compound by analyzing peptides presented on MHC class I2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Beclin 1 regulates recycling endosome and is required for skin development in mice2019

Author(s)

Journal Title

DOI

Data Source

Honda Shinya 本田真也

HONDA Shinya 本田真也