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KOTANI YASUHIRO  小谷 恭弘

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… Alternative Names

Kotani Yasuhiro  小谷 恭弘

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Researcher Number 90534678
Other IDs
Affiliation (Current) 2026: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2026: 岡山大学, 医歯薬学域, 准教授
2019 – 2023: 岡山大学, 医歯薬学総合研究科, 准教授
2017: 岡山大学, 大学病院, 助教
2016 – 2017: 岡山大学, 医歯薬学総合研究科, 助教
2015: 岡山大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55060:Emergency medicine-related / Cardiovascular surgery
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Basic Section 55060:Emergency medicine-related / Basic Section 90110:Biomedical engineering-related / Basic Section 90130:Medical systems-related / Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
心不全 / フォンタン不全 / フォンタン循環 / 心臓移植 / 心筋保護 / 補助循環 / 右心不全 / 右心補助 / Ex vivo perfusion / Ex-vivo perfusion … More / 心機能 / 調節再灌流 / 心停止ドナー / 再還流 … More
Except Principal Investigator
先天性心疾患 / ゲノム解析 / 心臓移植 / 肺静脈狭窄予防 / 肺静脈狭窄 / 全ゲノム解析 / 総肺静脈還流異常症 / 心移植 / 心停止ドナー / 心筋虚血再灌流障害 / 心筋虚血再還流障害 / 心臓マイクロダイアリシス / 血行動態 / シミュレーション / 自律神経機能 / 心拍変動解析 / 完全大血管転位症 / 完全大血管転位 / シングルセル解析 / 心臓手術 / 総肺静脈環流異常症 / 病態解明 / 血管修復 / 創薬ターゲット / 心臓血管外科 / 空間的シングルセルRNA解析 / 成人先天性心疾患 / 二次性三尖弁閉鎖不全症 / 房室中隔欠損症 / レジストリ / 左心低形成症候群 / Vascular Surgery / Hemocompatibility / Albumin Coating / Vascular Graft / 人工血管 / ePTFE / アルブミン / Diamond-like Carbon / 血液適合性 / 生体適合性 / 異物界面反応 / タンパク吸着 / アルブミン付着 / ePTFE人工血管 / ダイヤモンドライクカーボン / Cardiac surgery / Etiological Analysis / NG sequencer / Whole genome sequence / TAPVC / 原因遺伝子 / 病因解明 / トリオ解析 / 次世代シーケンサー / 純型肺動脈閉鎖症 / 植込み型補助人工心臓 / 植え込み型補助人工心臓 / 心筋虚血再灌流傷害 / セロトニン / カーボンファイバー / FrankーStarlingの法則 / 単離心筋細胞の力学機能評価 / 長さ張力関係 / Frank -Starlingの法則 / Force-Length relation / 力学機能評価 / frank-starlingの法則 / 機械伸展刺激 / ヒト単離心筋細胞 / Force-Length reration / 体外式搬送システム / 心機能評価 / 心筋保護 / β3アドレナリン受容体 / カテコラミン / ミオグロビン / β3受容体作動薬 / β3受容体作動薬 / ベッドサイド Less
  • Research Projects

    (20 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (31 People)
  •  呼吸停止による心停止における心筋障害の解明

    • Principal Investigator
      徳田 雄平
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  Development of a prognostic biomarker for Fontan circulatory failure in patients with single-ventricle syndrome using heart rate variability analysis

    • Principal Investigator
      福家 聡一郎
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Japanese Red Cross Okayama Hospital(Clinical Research Center)
  •  左心低形成症候群の予後予測を目指した国内患者レジストリと生体試料レポジトリの構築

    • Principal Investigator
      笠原 真悟
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  房室中隔欠損症のトリオゲノム解析

    • Principal Investigator
      森岡 慧
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  先天性心疾患術後の二次性三尖弁閉鎖不全症の手術適応決定のためのエビデンス創出

    • Principal Investigator
      杜 徳尚
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      Okayama University
  •  Exploration of Therapeutic Targets for the Prevention of Pulmonary Vein Stenosis Following Surgical Repair of Total Anomalous Pulmonary Venous Connection

    • Principal Investigator
      枝木 大治
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Iwate Medical University
  •  Identification of the gene responsible for transposition of the great arteries

    • Principal Investigator
      加藤 源太郎
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  フォンタン循環不全に対する最適な左心補助循環の検討Principal Investigator

    • Principal Investigator
      小谷 恭弘
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  両心室機能評価装置を搭載した体外式搬送システムによる心停止ドナー心の選別

    • Principal Investigator
      廣田 真規
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Showa University
      Okayama University
  •  Cause analysis of TAPVC generation using whole-genome analysis by next-generation sequencer

    • Principal Investigator
      辻 龍典
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Iwate Medical University
  •  Development of albumin pre-coating DLC coated artificial vascular graft

    • Principal Investigator
      大澤 晋
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  心虚血・再灌流時のセロトニン動態への薬理学的介入による心筋細胞傷害軽減

    • Principal Investigator
      黒子 洋介
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  Development of a hemodynamic simulator of implantable ventricular assist devices for congenital heart diseases

    • Principal Investigator
      清水 秀二
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Investigation of gene expression in pulmonary atresia and intact ventricular septum

    • Principal Investigator
      木佐森 永理
    • Project Period (FY)
      2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  Evaluation of isolated human cardiomyocyte function via the force–length relationship

    • Principal Investigator
      Komatsu Hiroaki
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Okayama University
  •  Mechanical support for right heart failure in single ventricle physiologyPrincipal Investigator

    • Principal Investigator
      Kotani Yasuhiro
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  Development of an ex-vivo heart perfusion system to monitor pre-transplant cardiac function for a DCD donor heart

    • Principal Investigator
      hirota masanori
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Showa University
      Okayama University
  •  Development of a bed-side hemodynamic simulator for complex congenital heart anomaly

    • Principal Investigator
      Shimizu Shuji
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      National Cardiovascular Center Research Institute
  •  Effects of beta3 adrenergic receptor agonist on Myocardial Ischemia and Reperfusion

    • Principal Investigator
      Kuroko Yosuke
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Okayama University
  •  Heart Transplantation using Ex-vivo Heart PerfusionPrincipal Investigator

    • Principal Investigator
      KOTANI YASUHIRO
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cardiovascular surgery
    • Research Institution
      Okayama University

All 2024 2023 2022 2020 2017

All Journal Article Presentation

  • [Journal Article] Effects of systemic ventricular assist in failing Fontan patients: a theoretical analysis using a computational model2024

    • Author(s)
      Kisamori Eiri、Kotani Yasuhiro、Shishido Toshiaki、Kasahara Shingo、Shimizu Shuji
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 74 Issue: 1 Pages: 53-53

    • DOI

      10.1186/s12576-024-00946-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K12794, KAKENHI-PROJECT-24K12155
  • [Journal Article] Evaluation of the effects of fenestration in Fontan circulation using a lumped parameter model2024

    • Author(s)
      Horio Naohiro、Shimizu Shuji、Kotani Yasuhiro、Miyahara Yoshinori、Kasahara Shingo
    • Journal Title

      The Journal of Physiological Sciences

      Volume: 74 Issue: 1 Pages: 58-58

    • DOI

      10.1186/s12576-024-00947-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K12794, KAKENHI-PROJECT-24K12155
  • [Journal Article] Intracoronary Cardiac Progenitor Cells in Single Ventricle Physiology: The PERSEUS (Cardiac Progenitor Cell Infusion to Treat Univentricular Heart Disease) Randomized Phase 2 Trial.2017

    • Author(s)
      Ishigami S, Ohtsuki S, Eitoku T, Ousaka D, Kondo M, Kurita Y, Hirai K, Fukushima Y, Baba K, Goto T, Horio N, Kobayashi J, Kuroko Y, Kotani Y, Arai S, Iwasaki T, Sato S, Kasahara S, Sano S, Oh H.
    • Journal Title

      Circ Res

      Volume: 120 Pages: 1162-1173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10215
  • [Presentation] Understanding of Fontan Circulation: The introduction of Hemodynamic Simulation2024

    • Author(s)
      Shuji Shimizu, Yasuhiro Kotani, Koji Uemura, Shingo Kasahara, Toshiaki Shishido
    • Organizer
      第101回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-22K12794
  • [Presentation] コンピュータ・シミュレーションを用いたフォンタン循環における植え込み型補助人工心臓の効果の検証2023

    • Author(s)
      清水秀二、木佐森永理、小谷恭弘、笠原真悟、宍戸稔聡
    • Organizer
      第62回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-22K12794
  • [Presentation] フォンタン不全における左心補助循環とフェネストレーションの有効性の検討2023

    • Author(s)
      清水秀二、小谷恭弘、笠原真悟、宍戸稔聡
    • Organizer
      第44回日本循環制御医学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-22K12794
  • [Presentation] Fenestration improves the hemodynamics in the failing Fontan patients under mechanical circulatory support2023

    • Author(s)
      Shuji Shimizu, Yasuhiro Kotani, Toshiaki Shishido
    • Organizer
      日本生理学会第100回記念大会
    • Data Source
      KAKENHI-PROJECT-22K12794
  • [Presentation] Effects of ventricular assist device with a fenestration in the failing Fontan circulation: a theoretical analysis using a lumped parameter model2023

    • Author(s)
      Shuji Shimizu, Yasuhiro Kotani, Naohiro Horio, Eiri Kisamori, Koji Uemura, Shingo Kasahara, Toshiaki Shishido
    • Organizer
      ESC Congress 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K12794
  • [Presentation] Fenestration improves the hemodynamics in the failing Fontan patients under mechanical circulatory support2023

    • Author(s)
      Shuji Shimizu, Yasuhiro Kotani, Toshiaki Shishido
    • Organizer
      日本生理学会第100回記念大会
    • Data Source
      KAKENHI-PROJECT-19K09282
  • [Presentation] フォンタン不全における左心補助循環とフェネストレーションの有効性の検討2023

    • Author(s)
      清水秀二、小谷恭弘、笠原真悟、宍戸稔聡
    • Organizer
      第44回日本循環制御医学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-20K09266
  • [Presentation] What is the optimal circulatory assist for failing Fontan? : Experimental study for clinical implication2022

    • Author(s)
      Naoya Sakoda, Yasuhiro Kotani, Yasuyuki Kobayashi, Daichi Edaki, Shingo Kasahara
    • Organizer
      The 102nd Annual meeting of American Society for Thoracic Surgery
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09266
  • [Presentation] What is the optimal circulatory assist for failing Fontan? : Experimental study for clinical implication2022

    • Author(s)
      迫田直也、小谷恭弘、小林泰幸、枝木大治、笠原真悟
    • Organizer
      American Association for Thoracic Surgery 102nd Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09266
  • [Presentation] 左室心筋粘性の存在は不全心の左室心筋弾性を見かけ上、低下させる2022

    • Author(s)
      清水秀二、小谷恭弘、宍戸稔聡
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-19K09282
  • [Presentation] Effects of the left ventricular viscosity on a failed heart: An in-silico an alysis2020

    • Author(s)
      Shimizu Shuji、Kotani Yasuhiro、Shishido Toshiaki
    • Organizer
      第59回日本生体医工学会大会
    • Data Source
      KAKENHI-PROJECT-19K09282
  • 1.  Shimizu Shuji (80443498)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 11 results
  • 2.  笠原 真悟 (90233692)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 3 results
  • 3.  Kuroko Yosuke (20459184)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  山崎 悟 (70348796)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  中谷 明弘 (60301149)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  野村 征太郎 (10722118)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  藤井 泰宏 (40534673)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  hirota masanori (90407528)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  宍戸 稔聡 (60300977)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 10.  朔 啓太 (40567385)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  徳田 雄平 (50998226)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  鈴木 浩之 (80969204)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  森岡 慧 (70976258)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  OH Hidemasa (50372579)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  Komatsu Hiroaki (40894952)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  貝原 恵子 (60638641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  入部 玄太郎 (90284885)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  秋山 剛 (70202554)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  木佐森 永理 (60894954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  辻 龍典 (10839004)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  大澤 晋 (20643414)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  中谷 達行 (50520920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  逢坂 大樹 (70839141)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  杜 徳尚 (70600641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  石津 智子 (10507859)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  赤木 禎治 (80231801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  椎名 由美 (90436361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  建部 俊介 (90456062)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  枝木 大治 (90969205)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  加藤 源太郎 (10365744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  福家 聡一郎 (10816101)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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