Terashima Yuya 寺島裕也

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TERASHIMA Yuya 寺島裕也

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Researcher Number	90538729
Other IDs
Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2025: 東京大学, 医学部附属病院, 客員研究員
Affiliation (based on the past Project Information) *help	2025: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2018 – 2024: 東京理科大学, 研究推進機構生命医科学研究所, 講師 2023: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2021 – 2023: 東京大学, 医学部附属病院, 客員研究員 2016 – 2017: 東京大学, 大学院医学系研究科(医学部), 助教 2012 – 2015: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Hygiene and public health / Basic Section 49070:Immunology-related / Immunology Except Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Basic Section 53030:Respiratory medicine-related / Basic Section 56010:Neurosurgery-related / Basic Section 55040:Respiratory surgery-related / Basic Section 56020:Orthopedics-related / Basic Section 49070:Immunology-related
Keywords	Principal Investigator ケモカイン / 創薬 / 白血球遊走 / 細胞内シグナル / PI3K / FROUNT / 炎症 / 細胞遊走 / 予防医学 / 予防・治療 … More / シグナル制御 / ケモカイン受容体 / ペプチド / 創薬標的 / GPCR / 遺伝子改変マウス … More Except Principal Investigator ケモカイン / マクロファージ / 炎症シグナリング / 生体内分子置換反応 / ＭＲＩ / ＮＭＲ / システイン / フロント / ドラッグデザイン / がん / タンパク質の立体構造 / ケモカイン受容体 / ドラッグリポジショニング / 血管性認知症 / 慢性拒絶 / 拒絶反応 / 拒絶 / 急性拒絶反応 / 急性拒絶 / 肺移植 / 急性呼吸窮迫症候群 / COVID-19 / 間質性肺炎 / 間質性肺疾患 / 肺気腫 / マクロファージ活性化症候群 / 炎症性サイトカイン / MRI / NMR / 滑膜マクロファージ / 滑膜 / 変形性関節症 / osteoarthritis / osteoclast / osteoporosis / Disulfiram / Frount / 細胞形態 / 白血球遊走 / 細胞遊走 / 単球 / FROUNT / 肺線維症 / 気腫 / 線維化 / フロント阻害剤 / 気道炎症 / 難治性重症呼吸器疾患 Less

NMR・MRIを用いた新規作用機序の抗炎症化合物の開発
- Principal Investigator
  
  吉永壮佐
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kumamoto University
機能性システインの化学修飾に基づく新規作用機序の炎症制御化合物の開発
- Principal Investigator
  
  寺沢宏明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kumamoto University
ケモカイン受容体デュアル制御分子に着目した血管性認知症に対する疾患修飾薬の確立
- Principal Investigator
  
  須田智
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Saitama Medical University
  Nippon Medical School
The activation mechanism of PI3K by FROUNT in leukocyte chemotaxisPrincipal Investigator
- Principal Investigator
  
  寺島裕也
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
重症COVID-19合併ARDS・マクロファージ活性化症候群の新規治療戦略の確立
- Principal Investigator
  
  漆山博和
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  The University of Tokyo
The role of macrophages in chronic rejection after lung transplantation and regulatioon of macrophage activities by FROUNT inhibition
- Principal Investigator
  
  Sato Masaaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Tokyo
疾患病態を反映するマクロファージの免疫形態学的指標の探索
- Principal Investigator
  
  遠田悦子
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Nippon Medical School
A possible and novel treatment for osteoporosis by controlling the Frount signal pathway.
- Principal Investigator
  
  Yamagami Ryota
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  The University of Tokyo
A study of in vivo cysteine-mediated molecular replacement reactions, based on NMR and MRI methods
- Principal Investigator
  
  Terasawa Hiroaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kumamoto University
Development of new treatment strategy for intractable severe respiratory disease focusing on the macrophage-FROUNT
- Principal Investigator
  
  Yamauchi Yasuhiro
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tokyo University of Foreign Studies
  The University of Tokyo
Cellular and molecular signals mediated by chemokine receptor-associating molecule FROUNTPrincipal Investigator
- Principal Investigator
  
  Terashima Yuya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene and public health
- Research Institution
  Tokyo University of Science
  The University of Tokyo
Exploration of alpha helix domains for drug targetPrincipal Investigator
- Principal Investigator
  
  Terashima Yuya
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene and public health
- Research Institution
  The University of Tokyo
Expressional and functional analysis of FROUNT in micePrincipal Investigator
- Principal Investigator
  
  TERASHIMA Yuya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] がん基盤生物学「ケモカイン受容体シグナル制御分子フロント(フロント)へのパラダイムシフト」2013
- Author(s)
  寺島裕也, 他
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24790462
[Journal Article] Disulfiram treatment suppresses antibody-producing reactions by inhibiting macrophage activation and B cell pyrimidine metabolism2024
- Author(s)
  Chen Weili、Toda Etsuko、Takeuchi Kazuhiro、Sawa Yurika、Wakamatsu Kyoko、Kuwahara Naomi、Ishikawa Arimi、Igarashi Yuri、Terasaki Mika、Kunugi Shinobu、Terasaki Yasuhiro、Yamada Kazuhiko、Terashima Yuya、Shimizu Akira
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1
- DOI
  10.1038/s42003-024-06183-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07553
[Journal Article] Disulfiram, an Anti-alcoholic Drug, Targets Macrophages and Attenuates Acute Rejection in Rat Lung Allografts2024
- Author(s)
  Yoshiyasu Nobuyuki、Matsuki Rei、Sato Masaaki、Urushiyama Hirokazu、Toda Etsuko、Terasaki Yasuhiro、Suzuki Masaki、Shinozaki-Ushiku Aya、Terashima Yuya、Nakajima Jun
- Journal Title
  
  Transplant International
  
  Volume: 37
- DOI
  10.3389/ti.2024.12556
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07553, KAKENHI-PROJECT-20K08553, KAKENHI-PROJECT-21K08898
[Journal Article] Disulfiram Ophthalmic Solution Inhibited Macrophage Infiltration by Suppressing Macrophage Pseudopodia Formation in a Rat Corneal Alkali Burn Model2023
- Author(s)
  Ikebukuro Toyo、Arima Takeshi、Kasamatsu Momoko、Nakano Yuji、Tobita Yutaro、Uchiyama Masaaki、Terashima Yuya、Toda Etsuko、Shimizu Akira、Takahashi Hiroshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 1 Pages: 735-735
- DOI
  10.3390/ijms24010735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07553
[Journal Article] Inhibition of the chemokine signal regulator FROUNT by disulfiram ameliorates crescentic glomerulonephritis2022
- Author(s)
  Toda Etsuko、Sawada Anri、Takeuchi Kazuhiro、Wakamatsu Kyoko、Ishikawa Arimi、Kuwahara Naomi、Sawa Yurika、Hatanaka Saeko、Kokubo Kana、Makino Kosho、Takahashi Hideyo、Endo Yoko、Kunugi Shinobu、Terasaki Mika、Terasaki Yasuhiro、Matsushima Kouji、Terashima Yuya、Shimizu Akira
- Journal Title
  
  Kidney International
  
  Volume: 102 Issue: 6 Pages: 1276-1290
- DOI
  10.1016/j.kint.2022.07.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07553, KAKENHI-PROJECT-20K08553, KAKENHI-PROJECT-20K09680, KAKENHI-PROJECT-17K11299
[Journal Article] Disulfiram Produces Potent Anxiolytic-Like Effects Without Benzodiazepine Anxiolytics-Related Adverse Effects in Mice2022
- Author(s)
  Saitoh Akiyoshi、Nagayama Yoshifumi、Yamada Daisuke、Makino Kosho、Yoshioka Toshinori、Yamanaka Nanami、Nakatani Momoka、Takahashi Yoshino、Yamazaki Mayuna、Shigemoto Chihiro、Ohashi Misaki、Okano Kotaro、Omata Tomoki、Toda Etsuko、Sano Yoshitake、Takahashi Hideyo、Matsushima Kouji、Terashima Yuya
- Journal Title
  
  Frontiers in Pharmacology
  
  Volume: 13
- DOI
  10.3389/fphar.2022.826783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15716, KAKENHI-PROJECT-20K07553
[Journal Article] マクロファージの動きを制御するFROUNTによるがん免疫応答の修飾作用2021
- Author(s)
  遠田悦子、寺島裕也
- Journal Title
  
  Medical Science Digest
  
  Volume: 47 Pages: 52-53
- Data Source
  KAKENHI-PROJECT-20K07553
[Journal Article] アルコール依存症治療薬ジスルフィラムによるがん抑制効果の分子標的2021
- Author(s)
  遠田悦子、寺島裕也
- Journal Title
  
  糖尿病・内分泌代謝科
  
  Volume: 53 Pages: 37-44
- NAID
  40022472572
- Data Source
  KAKENHI-PROJECT-20K07553
[Journal Article] Rational Design of Monodispersed Mutants of Proteins by Identifying Aggregation Contact Sites Using Solubilizing Agents2020
- Author(s)
  Tsuji Tatsuichiro、Yoshinaga Sosuke、Takeda Mitsuhiro、Sato Takafumi、Sonoda Akihiro、Ishida Norihito、Yunoki Kaori、Toda Etsuko、Terashima Yuya、Matsushima Kouji、Terasawa Hiroaki
- Journal Title
  
  Biochemistry
  
  Volume: 59 Issue: 39 Pages: 3639-3649
- DOI
  10.1021/acs.biochem.0c00414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07000, KAKENHI-PROJECT-20H03376
[Journal Article] 1H, 13C and 15N resonance assignments for a chemokine receptor-binding domain of FROUNT, a cytoplasmic regulator of chemotaxis2018
- Author(s)
  Yoshinaga Sosuke、Ishida Norihito、Tsuji Tatsuichiro、Sonoda Akihiro、Yunoki Kaori、Takeda Mitsuhiro、Toda Etsuko、Terashima Yuya、Matsushima Kouji、Terasawa Hiroaki
- Journal Title
  
  Biomolecular NMR Assignments
  
  Volume: 印刷中 Issue: 2 Pages: 259-262
- DOI
  10.1007/s12104-018-9819-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09095, KAKENHI-PROJECT-17K15716, KAKENHI-PROJECT-17K08241
[Journal Article] Efficient identification of compounds suppressing protein precipitation via solvent screening using serial deletion mutants of the target protein2018
- Author(s)
  Yunoki Kaori、Yoshinaga Sosuke、Takeda Mitsuhiro、Nagano Ryohei、Tsuchiya Yusuke、Sonoda Akihiro、Tsuji Tatsuichiro、Hirakane Makoto、Toda Etsuko、Terashima Yuya、Matsushima Kouji、Terasawa Hiroaki
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 2 Pages: 70-79
- DOI
  10.1111/gtc.12554
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09095, KAKENHI-PROJECT-17K15716, KAKENHI-ORGANIZER-17H06391
[Journal Article] Identification and Preparation of a Novel Chemokine Receptor-Binding Domain in the Cytoplasmic Regulator FROUNT.2017
- Author(s)
  Sonoda A, Yoshinaga S, Yunoki K, Ezaki S, Yano K, Takeda M, Toda E, Terashima Y, Matsushima K, Terasawa H.
- Journal Title
  
  Mol Biotechnol
  
  Volume: 印刷中 Issue: 4-5 Pages: 141-150
- DOI
  10.1007/s12033-017-0002-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-26860317, KAKENHI-PROJECT-16K09095, KAKENHI-PROJECT-17K15716
[Journal Article] Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage.2016
- Author(s)
  Tan X, Fujiu K, Manabe I, Nishida J, Yamagishi R, Terashima Y, Matsushima K, Kaburaki T, Nagai R, Yanagi Y.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 8 Pages: e0160985-e0160985
- DOI
  10.1371/journal.pone.0160985
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04824, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-16H05840, KAKENHI-PROJECT-16K09095
[Journal Article] Robust　anti-tumor effects of combined anti-CD4 depleting antibody and anti-PD-1/PD-L1　immune checkpoint antibody treatment in mice.2015
- Author(s)
  Ueha S, Yokochi S, Ishiwata Y, Ogiwara H, Chand K, Nakajima T, Hachiga K,　Shichino S, Terashima Y, Toda E, Shand FH, Kakimi K, Ito S, Matshushima K.
- Journal Title
  
  Cancer Immunol Res.
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670326
[Journal Article] ケモカインシグナル2015
- Author(s)
  遠田悦子、寺島裕也、松島綱治
- Journal Title
  
  生体の科学
  
  Volume: 66 Pages: 412-413
- Data Source
  KAKENHI-PROJECT-26670326
[Journal Article] Structural basis for the binding of the membrane-proximal C-terminal region of chemokine receptor CCR2 with the cytosolic regulator FROUNT2014
- Author(s)
  Esaki K, Yoshinaga S, Tsuji T, Toda E, Terashima Y, Saitoh T, Kohda D, Kohno T, Osawa M, Ueda T, Shimada I, Matsushima K, Terasawa H
- Journal Title
  
  FEBS J
  
  Volume: 281 Issue: 24 Pages: 552-566
- DOI
  10.1111/febs.13096
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-21121001, KAKENHI-PROJECT-24590048, KAKENHI-PUBLICLY-25121707, KAKENHI-PROJECT-26670326, KAKENHI-PROJECT-26860317
[Journal Article] Identification of a binding element for the cytoplasmic regulator FROUNTin the membrane-proximal C-terminal region of chemokine receptors CCR2 and CCR5.2014
- Author(s)
  Toda E, Terashlma Y, Esakii K, Yoshinaga S, Sugihara M, Kofuku Y, Shimada I, Suwa M, Kanegasaki S, Terasawa H, Matsushima K.
- Journal Title
  
  Biochemical Journal
  
  Volume: Vol.457 Issue: 2 Pages: 313-322
- DOI
  10.1042/bj20130827
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J40099, KAKENHI-ORGANIZER-21121001, KAKENHI-PLANNED-21121002, KAKENHI-PROJECT-24790462, KAKENHI-PROJECT-26670326, KAKENHI-PROJECT-26860317
[Journal Article] 腫瘍会合性マクロファージ2013
- Author(s)
  松島綱治、上羽悟史、寺島裕也
- Journal Title
  
  腫瘍免疫学とがん免疫療法
  
  Volume: 実験医学増刊号 Pages: 48-52
- Data Source
  KAKENHI-PROJECT-24790462
[Journal Article] ケモカイン受容体CCR2, CCR5とシグナル促進分子フロント2013
- Author(s)
  遠田悦子、寺島裕也、松島綱治
- Journal Title
  
  臨床免疫・アレルギー科(科学評論社)
  
  Pages: 386-391
- NAID
  40019636502
- Data Source
  KAKENHI-PROJECT-24790462
[Journal Article] ケモカイン受容体CCR2, CCR5とシグナル促進分子フロント2013
- Author(s)
  遠田悦子、寺島裕也、松島綱治
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 59巻 Pages: 386-391
- NAID
  40019636502
- Data Source
  KAKENHI-PROJECT-24790462
[Journal Article] 腫瘍免疫学とがん免疫療法2013
- Author(s)
  松島綱治、上羽悟史、寺島裕也
- Journal Title
  
  実験医学増刊号(羊土社)
  
  Pages: 48-52
- Data Source
  KAKENHI-PROJECT-24790462
[Journal Article] ケモカイン受容体シグナル制御分子フロント（フロント）へのパラダイムシフト2013
- Author(s)
  寺島裕也、遠田悦子、松島綱治
- Journal Title
  
  がん基盤生物学
  
  Volume: 次世代がん研究Update Pages: 130-136
- Data Source
  KAKENHI-PROJECT-24790462
[Presentation] CCR2/5-associated FROUNT regulates macrophage cytokine expression through modulation of MAP kinase pathway2024
- Author(s)
  Etsuko Toda,Kouji Matsushima,Yuya Terashima,Akira Shimizu
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07553
[Presentation] Functional MRI analyses of pain transmission in brains of chronic pain model animals2024
- Author(s)
  Kawachi, Y., Shinjo, T., Terashima, Y., Toda, E., Matsushima, K., 〇Yoshinaga, S., and Terasawa, H.
- Organizer
  The 11th Takeda Science Foundation Symposium on PharmaSciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27315
[Presentation] ケモカイン受容体CCR2/CCR5シグナル制御因子FROUNTはマクロファージの炎症性サイトカイン発現を調節する2024
- Author(s)
  遠田悦子,竹内和博,寺崎美佳,功刀しのぶ,寺崎泰弘,寺島裕也,清水章
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K07553
[Presentation] FROUNT阻害剤ジスルフィラムによる半月体形成性糸球体腎炎抑制効果2023
- Author(s)
  遠田悦子,澤田杏理,竹内和博,畑中彩恵子,寺崎美佳,功刀しのぶ,寺崎泰弘,松島綱治,寺島裕也,清水章
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K07553
[Presentation] Preparation of phosphorylated FROUNT protein, a regulator of chemokine receptors, for structural and functional analyses2022
- Author(s)
  Uchida, K., Yoshinaga, S., Sato, T., Takeda, M., Terashima, Y., Toda, E., Matsushima, K., and Terasawa, H.
- Organizer
  日本生物物理学会第６０回年会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] In-cell NMR analysis of the structure of a chemokine-signaling protein and the interaction with its inhibitory compound2022
- Author(s)
  Sato, T., Udatsu, H., Higashi, A., Takeda, M., Terashima, Y., Toda, Et., Matsushima, K., Yoshinaga, S., and Terasawa, H.
- Organizer
  第50回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] 細胞遊走シグナル制御因子R1-15の立体構造解析と細胞内NMR解析に向けた試料調製2022
- Author(s)
  松村早姫、吉永壮佐、佐藤貴文、武田光広、寺島裕也、遠田悦子、松島綱治、寺沢宏明
- Organizer
  第１６回日本分子イメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] 熱安定性の低いタンパク質のIn-cell NMR解析に向けたタンパク質の培養細胞への導入法の検討2022
- Author(s)
  宇田津晴香、東愛理、佐藤貴文、武田光広、寺島裕也、遠田悦子、松島綱治、吉永壮佐、寺沢宏明
- Organizer
  第１６回日本分子イメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] FROUNT inhibitor disulfiram ameliorates crescentic glomerulonephritis through the inhibition of monocytes/macrophage migration and activation2022
- Author(s)
  Etsuko Toda, Anri Sawada, Kazuhiro Takeuchi, Yuya Terashima, Kouji Matsushima, A, Shinobu Kunugi, Mika Terasaki, Yasuhiro Terasaki, Akira Shimizu
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07553
[Presentation] ケモカイン受容体制御因子FROUNTのリン酸化による立体構造とケモカイン受容体結合能への影響の解析2021
- Author(s)
  内田恵介、吉永壮佐、佐藤貴文、武田光広、寺島裕也、遠田悦子、松島綱治、寺沢宏明
- Organizer
  第１５回日本分子イメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] A cell migration-promoting molecule FROUNT regulates macrophage activation2021
- Author(s)
  Etsuko Toda, Yuya Terashima and Kouji Matsushima
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07553
[Presentation] In-cell NMRを用いたケモカインシグナル制御タンパク質の細胞内における構造評価2021
- Author(s)
  佐藤貴文、吉永壮佐、東愛理、宇田津晴香、武田光広、寺島裕也、遠田悦子、松島綱治、寺沢宏明
- Organizer
  第１５回日本分子イメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] NMRを用いたタンパク質の細胞内解析に向けた自己会合抑制変異体の利用によるスペクトル改善の試み2021
- Author(s)
  Higashi, A., Sato, T., Udatsu, H., Yoshinaga, S., Takeda, M., Toda, E., Terashima, Y., Matsusima, K., and Terasawa, H
- Organizer
  第49回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] In-cell NMR analysis of an anticancer candidate compound against a chemokine-signaling protein FROUNT2020
- Author(s)
  Yoshinaga, S., Sato, T., Higashi, A., Takeda, M., Terashima, Y., Toda, E., Matsushima, K., and Terasawa, H.
- Organizer
  日本生物物理学会第５８回年会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] In-cell analysis of an inhibitory compound against a chemokine-signaling protein with the in-cell NMR method2020
- Author(s)
  Sato, T., Yoshinaga, S., Higashi, A., Takeda, M., Terashima, Y., Toda, E., Matsushima, K., and Terasawa, H.
- Organizer
  第４８回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-20H03376
[Presentation] Chemokine receptor-associating molecule FROUNT is a new class of target to control tumor-associated macrophages2019
- Author(s)
  Yuya Terashima, Etsuko Toda and Kouji Matsushima
- Organizer
  KeystoneSymposia
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] 腫瘍促進性マクロファージ制御分子、フロントの機能を阻害する抗がん薬の開発研究2018
- Author(s)
  寺島裕也、遠田悦子、奥村和弘、板倉明司、大辻幹哉、永瀬浩喜、松島綱治
- Organizer
  第２２回　日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] 腫瘍促進性マクロファージ制御分子、フロントの阻害を機序とした抗がん薬の非臨床研究2018
- Author(s)
  寺島裕也、遠田悦子、板倉明司、松島綱治
- Organizer
  第17回分子予防環境医学研究会
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] ケモカイン受容体会合分子フロントを標的とした腫瘍促進性マクロファージ制御抗がん薬の開発2018
- Author(s)
  寺島裕也、遠田悦子、板倉明司、松島綱治
- Organizer
  第８３回日本インターフェロン・サイトカイン学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] FROUNT is a novel target to control chemotactic response of tumor-associated macrophage2017
- Author(s)
  Yuya Terashima, Etsuko Toda, Meiji Itakura and Kouji Matsushima
- Organizer
  5th Annual Meeting of the International Cytokine and Interferon Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] ケモカイン受容体シグナル促進分子フロント（FROUNT）を創薬標的として腫瘍促進性マクロファージを制御する2017
- Author(s)
  寺島裕也、遠田悦子、大辻幹哉、松島綱治
- Organizer
  第3回骨免疫学会
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] 細胞動態の分子メカニズムに着目した疾患の診断/治療/予防法の研究開発2017
- Author(s)
  寺島裕也
- Organizer
  第87回日本衛生学会学術総会
- Place of Presentation
  宮崎県シーガイヤ・コンベンションセンター
- Year and Date
  2017-03-26
- Invited
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] ケモカイン受容体シグナル制御分子、フロント（FROUNT）の機能を阻害して腫瘍促進性マクロファージを制御する2017
- Author(s)
  寺島裕也、遠田悦子、大辻幹哉、松島綱治
- Organizer
  第16回分子予防環境医学研究会
- Place of Presentation
  熊本市国際交流会館
- Year and Date
  2017-02-03
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] アカデミア発創薬探索研究、疾患に関わる細胞動態のメカニズムとその制御法2016
- Author(s)
  寺島裕也
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター・東北大学
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] ケモカイン受容体シグナル制御分子FROUNT（フロント）を標的とした新規抗がん剤開発2016
- Author(s)
  寺島裕也、松島綱治
- Organizer
  第86回日本衛生学会学術総会
- Place of Presentation
  旭川市民文化会館
- Year and Date
  2016-05-11
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] 疾患の発症/悪化の鍵となる免疫細胞の動くメカニズムを解明してコントロールする2016
- Author(s)
  寺島裕也、松島綱治
- Organizer
  第14回日本予防医学会学術総会
- Place of Presentation
  日本科学未来館（東京）
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-16K09095
[Presentation] A chemokine receptor-associating molecule FROUNT is required for macrophage infiltraion and tumor progression.2015
- Author(s)
  Yuya Terashima, Etsuko Toda, and Kouji Matsushima
- Organizer
  International Conference of Cancer Immunotherapy and Macrophages (ICCIM) 2015
- Place of Presentation
  Tokyo
- Year and Date
  2015-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670326
[Presentation] Identification of Small-Molecule Inhibitors of FROUNT.2013
- Author(s)
  寺島裕也
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24790462
[Presentation] Identification of Small-Molecule Inhibitors of FROUNT2013
- Author(s)
  寺島裕也、松島綱治
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-24790462
[Presentation] ケモカイン受容体とフロント間相互作用を阻害する低分子化合物の探索2013
- Author(s)
  遠田悦子、寺島裕也、松島綱治, 他
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-24790462
[Presentation] ケモカイン受容体とフロント間相互作用を阻害する低分子化合物の探索2012
- Author(s)
  寺島裕也、遠田悦子、松島綱治, 他
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-24790462
[Presentation] ケモカイン受容体CCR2/5と受容体会合分子フロントとの相互作用様式の解析2012
- Author(s)
  遠田悦子、寺島裕也、松島綱治
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡県福岡市
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-24790462
[Presentation] Intracellular blockade of chemotaxis via targeting GPCR helix8-associating molecule FROUNT
- Author(s)
  Yuya Terashima, Etsuko Toda, and Kouji Matsushima
- Organizer
  Keystone Synposia; The Biological Code of Cell Signaling
- Place of Presentation
  Steamboat Springs, Colorado USA
- Year and Date
  2015-01-01 – 2015-01-16
- Data Source
  KAKENHI-PROJECT-26670326
[Presentation] A chemokine receptor-associating molecule, FROUNT is required for tumor metastasis by regulating tumor microenvironment
- Author(s)
  Yuya Terashima and Kouji Matsushima
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670326

1. 漆山博和 (20725303)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 松島綱治 (50222427)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. 吉永壮佐 (00448515)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
4. Terasawa Hiroaki (10300956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
5. Sato Masaaki (00623109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 遠田悦子 (00589327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
7. 牧野宏章 (40784369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Yamauchi Yasuhiro (00323585)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Yamagami Ryota (00722191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 相馬邦彦 (20806583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 城大祐 (30376470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 千々松良太 (60803210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 矢野文子 (80529040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 武田光広 (90508558)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
15. 齋藤朗 (90591412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 寺崎泰弘 (50332870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 須田智 (00366733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 仁藤智香子 (30409172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 横堀将司 (70449271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 澤智裕 (30284756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 高橋秀依 (10266348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 永井良三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 嶋田一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 神田大輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Terashima Yuya 寺島 裕也

TERASHIMA Yuya 寺島 裕也

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The activation mechanism of PI3K by FROUNT in leukocyte chemotaxisPrincipal Investigator

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Cellular and molecular signals mediated by chemokine receptor-associating molecule FROUNTPrincipal Investigator

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Exploration of alpha helix domains for drug targetPrincipal Investigator

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Expressional and functional analysis of FROUNT in micePrincipal Investigator

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[Book] がん基盤生物学「ケモカイン受容体シグナル制御分子フロント(フロント)へのパラダイムシフト」2013

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[Journal Article] Disulfiram treatment suppresses antibody-producing reactions by inhibiting macrophage activation and B cell pyrimidine metabolism2024

Author(s)

Terashima Yuya 寺島裕也

TERASHIMA Yuya 寺島裕也

[Journal Article] Robust　anti-tumor effects of combined anti-CD4 depleting antibody and anti-PD-1/PD-L1　immune checkpoint antibody treatment in mice.2015