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Ishikawa Chie  石川 千恵

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ISHIKAWA Chie  石川 千恵

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Researcher Number 90542358
Other IDs
Affiliation (Current) 2025: 琉球大学, 亜熱帯島嶼科学超域研究推進機構, 助教
Affiliation (based on the past Project Information) *help 2013 – 2019: 琉球大学, 亜熱帯島嶼科学超域研究推進機構, 助教
Review Section/Research Field
Principal Investigator
Tumor biology
Keywords
Principal Investigator
HTLV-1 / 成人T細胞白血病 / Tax / 発現制御 / シグナル伝達 / 癌 / ウイルス / Ivermectin / Importazole / 原発性体腔液性リンパ腫 … More / AP-1 / NF-κB / イベルメクチン / インポータゾル / インポーチン / c-myc / ISL-1 / 成人T細胞白血病(ATL) / インターフェロン調節因子(IRF)5 / 成人T細胞白血病・リンパ腫 / TNF-α / インターフェロン(IFN)調節因子(IRF)5 / 成人T細胞白血病・リンパ腫(ATLL) Less
  • Research Projects

    (3 results)
  • Research Products

    (55 results)
  • Co-Researchers

    (2 People)
  •  Elucidation of pathogenesis and development of therapeutic strategy of adult T-cell leukemia with a focus on nuclear transport protein importinPrincipal Investigator

    • Principal Investigator
      Ishikawa Chie
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      University of the Ryukyus
  •  The role of LIM homeodomain transcription factor ISL-1 in leukemogenesis in ATLPrincipal Investigator

    • Principal Investigator
      ISHIKAWA Chie
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      University of the Ryukyus
  •  Constitutive expression of interferon regulatory factor, IRF5 in HTLV-1-infected T cells.Principal Investigator

    • Principal Investigator
      ISHIKAWA Chie
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      University of the Ryukyus

All 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

  • [Journal Article] Evaluation of artesunate for the treatment of adult T-cell leukemia/lymphoma2020

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori
    • Journal Title

      European Journal of Pharmacology

      Volume: 872 Pages: 172953-172953

    • DOI

      10.1016/j.ejphar.2020.172953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Effects of NVP-BEZ235, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, on HTLV-1-infected T-cell lines2018

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori.
    • Journal Title

      Oncology Letters

      Volume: 15 Pages: 5311-5317

    • DOI

      10.3892/ol.2018.7979

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Mitotic kinase PBK/TOPK as a therapeutic target for adult T-cell leukemia/lymphoma2018

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori.
    • Journal Title

      International Journal of Oncology

      Volume: 53 Pages: 801-814

    • DOI

      10.3892/ijo.2018.4427

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Mitotic kinase PBK/TOPK as a therapeutic target for adult T-cell leukemia/lymphoma2018

    • Author(s)
      Ishikawa Chie、Senba Masachika、Mori Naoki
    • Journal Title

      International Journal of Oncology

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Anti-adult T-cell leukemia/lymphoma activity of cerdulatinib, a dual SYK/JAK kinase inhibitor2018

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori.
    • Journal Title

      International Journal of Oncology

      Volume: 53 Pages: 1681-1690

    • DOI

      10.3892/ijo.2018.4513

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Butein inhibits NF-κB, AP-1 and Akt activation in adult T-cell leukemia/lymphoma2017

    • Author(s)
      Ishikawa Chie、Senba Masachika、Mori Naoki
    • Journal Title

      International Journal of Oncology

      Volume: 51 Issue: 2 Pages: 633-643

    • DOI

      10.3892/ijo.2017.4026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] In vitro and in vivo anti-primary effusion lymphoma activities of fucoidan extracted from Cladosiphon okamuranus Tokida2017

    • Author(s)
      Ishikawa Chie、Mori Naoki
    • Journal Title

      Oncology Reports

      Volume: 38 Issue: 5 Pages: 3197-3204

    • DOI

      10.3892/or.2017.5978

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Effects of NVP-BEZ235, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, on HTLV-1-infected T-cell lines.2017

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori.
    • Journal Title

      Oncology Letters

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Journal Article] Expression and significance of Pim-3 kinase in adult T-cell leukemia2017

    • Author(s)
      Ishikawa Chie、Senba Masachika、Hashimoto Tadashi、Imaizumi Atsushi、Mori Naoki
    • Journal Title

      European Journal of Haematology

      Volume: 99 Issue: 6 Pages: 495-504

    • DOI

      10.1111/ejh.12940

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Journal Article] Peridinin, a carotenoid, inhibits proliferation and survival of HTLV-1-infected T-cel lines.2016

    • Author(s)
      Chie Ishikawa, Takahiro Jomori, Junichi Tanaka, Masachika Senba, Naoki Mori.
    • Journal Title

      International Journal of Oncology

      Volume: 49 Issue: 4 Pages: 1713-1721

    • DOI

      10.3892/ijo.2016.3648

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Journal Article] Efficiency of AUY922 in mice with adult T-cell leukemia/lymphoma2016

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori.
    • Journal Title

      Oncology Letters

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Journal Article] Activation of PKC-δ in HTLV-1-infected T cells.2015

    • Author(s)
      Mori N, Ishikawa C, Senba M.
    • Journal Title

      Int J Oncol

      Volume: 46 Issue: 4 Pages: 1609-1618

    • DOI

      10.3892/ijo.2015.2848

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24592432, KAKENHI-PROJECT-25461428, KAKENHI-PROJECT-25830085
  • [Journal Article] Constitutive expression of IRF-5 in HTLV-1-infected T cells.2015

    • Author(s)
      Chie Ishikawa, Masachika Senba, Betsy J. Barnes, Naoki Mori.
    • Journal Title

      International Journal of Oncology

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Journal Article] Induction of IκB-ζ by Epstein-Barr virus latent membrane protein-1 and CD302015

    • Author(s)
      Chie Ishikawa, Masachika Senba, Naoki Mori.
    • Journal Title

      International Journal of Oncology

      Volume: 47 Issue: 6 Pages: 2197-2207

    • DOI

      10.3892/ijo.2015.3218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K18414, KAKENHI-PROJECT-25461428
  • [Journal Article] Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia2013

    • Author(s)
      Naoki Mori, Chie Ishikawa, Jun-Nosuke Uchihara, Takeshi Yasumoto
    • Journal Title

      Current Cancer Drug Targets

      Volume: VOL. 13 Issue: 8 Pages: 829-842

    • DOI

      10.2174/156800961131300093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461428, KAKENHI-PROJECT-25830085
  • [Journal Article] Hippuristanol reduces the viability of primary effusion lymphoma cells both in vitro and in vivo.2013

    • Author(s)
      Ishikawa C, Tanaka J, Katano H, Senba M, Mori N.
    • Journal Title

      Mar Drugs

      Volume: 11 Issue: 9 Pages: 3410-3423

    • DOI

      10.3390/md11093410

    • NAID

      120006986055

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592432, KAKENHI-PROJECT-25461428, KAKENHI-PROJECT-25830085
  • [Journal Article] Epstein-Barr virus latent membrane protein 1 induces CD69 expression through activation of nuclear factor-κB2013

    • Author(s)
      Chie Ishikawa, Naoki Mori
    • Journal Title

      International Journal of Oncology

      Volume: VOL. 42 Issue: 5 Pages: 1786-1792

    • DOI

      10.3892/ijo.2013.1871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461428, KAKENHI-PROJECT-25830085
  • [Journal Article] CD69 overexpression by human T-cell leukemia virus type 1 Tax transactivation.2013

    • Author(s)
      Ishikawa C, Kawakami H, Uchihara JN, Senba M, Mori N.
    • Journal Title

      Biochem Biophys Acta - Molecular Cell Research (BBA-Mol Cell Res),

      Volume: 1833 Issue: 6 Pages: 1542-1552

    • DOI

      10.1016/j.bbamcr.2013.03.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24592432, KAKENHI-PROJECT-25461428, KAKENHI-PROJECT-25830085
  • [Presentation] 成人T細胞白血病の新規治療標的MALT12019

    • Author(s)
      森直樹, 石川千恵
    • Organizer
      第6回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Importin β1 regulates cell growth and survival of KSHV-infected primary effusion lymphoma2019

    • Author(s)
      Naoki Mori, Chie Ishikawa
    • Organizer
      The 67th Annual Meeting of the Japanese Society for Virology
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] MALT1 as a novel therapeutic target for adult T-cell leukemia2019

    • Author(s)
      Naoki Mori, Chie Ishikawa
    • Organizer
      The 81st Annual Meeting of the Japanese Society of Hematology
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] CUDC-907, a new dual PI3K and HDAC inhibitor, blocks multiple signaling pathways in primary effusion lymphoma2019

    • Author(s)
      Naoki Mori, Chie Ishikawa
    • Organizer
      The 78th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] CUDC-907, a new dual PI3K and HDAC inhibitor, as ATL therapeutics.2018

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 77th Annual Meeting of the Japanese Cancer Association.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Evaluation of artesunate for the treatment of adult T-cell leukemia.2018

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 80th Annual Meeting of the Japanese Society of Hematology.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] 成人T細胞白血病の治療候補薬アルテスネイト.2018

    • Author(s)
      森直樹, 石川千恵.
    • Organizer
      第5回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Evaluation of artesunate for the treatment of primary effusion lymphoma.2018

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 77th Annual Meeting of the Japanese Cancer Association.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] SENP1, a new molecular target for ATL therapy.2018

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 66th Annual Meeting of the Japanese Society for Virology.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] PBK is a therapeutic target for KSHV-related primary effusion lymphoma.2017

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 65th Annual Meeting of the Japanese Society for Virology.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] インポーチンを標的としたATL治療戦略.2017

    • Author(s)
      森直樹, 石川千恵.
    • Organizer
      第4回日本HTLV-1学会学術集会.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] PBK, a serin-threonin kinase, as a therapeutic target for Hodgkin’s lymphoma.2017

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 76th Annual Meeting of the Japanese Cancer Association.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Targeting importins for therapy in adult T-cell leukemia.2017

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 79th Annual Meeting of the Japanese Society of Hematology.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Importin as a therapeutic target for ATL.2017

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 76th Annual Meeting of the Japanese Cancer Association.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Anti-ATL activity of dual PI3K and HDAC inhibitor CUDC-907.2017

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 65th Annual Meeting of the Japanese Society for Virology.
    • Data Source
      KAKENHI-PROJECT-17K07175
  • [Presentation] Mitotic kinase PBK/TOPK as a therapeutic target for ATL.2016

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 75th Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Activity of the novel dual SYK/JAK kinase inhibitor cerdulatinib against ATL.2016

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 75th Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Anti-ATL activity of cerdulatinib, a novel dual SYK/JAK kinase inhibitor.2016

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 64th Annual Meeting of the Japanese Society for Virology.
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Targeting mitotic kinase PBK/TOPK decreases growth and survival of HTLV-1-infected T-cell lines.2016

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 78th Annucal Meeting of the Japanese Society of Hematology.
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-10-13
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Effets of fucoidan against KSHV-related primary effusion lymphoma both in vitro and in vivo.2016

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 64th Annual Meeting of the Japanese Society for Virology.
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-10-23
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] ATLの新規治療標的分子PBK/TOPK2016

    • Author(s)
      森直樹、石川千恵
    • Organizer
      第3回日本HTLV-1学会学術集会
    • Place of Presentation
      鹿児島県市町村自治会館(鹿児島県鹿児島市)
    • Year and Date
      2016-08-26
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] ATLに選択的に発現しているPim-3を分子標的とした新たな治療法の開発2015

    • Author(s)
      森直樹、石川千恵
    • Organizer
      第2回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所講堂(東京都港区)
    • Year and Date
      2015-08-21
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Pim-3 kinase as a therapeutic target for ATL.2015

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 77th Annucal Meeting of the Japanese Society of Hematology.
    • Place of Presentation
      石川県立音楽堂(金沢市)
    • Year and Date
      2015-10-16
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Inhibition of proliferation and survival of HTLV-1-infected T-cell lines by peridinin.2015

    • Author(s)
      Naoki Mori, Chie Ishikawa, Jun-ichi Tanaka.
    • Organizer
      The 63rd Annual Meeting of the Japanese Society for Virology.
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Activity of the novel dual PI3K/mTOR inhibitor BEZ235 against ATL.2015

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 74th Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Activity of the novel dual PI3K/mTOR inhibitor BEZ235 against ATL.2015

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      The 63rd Annual Meeting of the Japanese Society for Virology.
    • Place of Presentation
      福岡国際会議場(福岡市)
    • Year and Date
      2015-11-22
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] Pim-3 kinase as a therapeutic target for ATL.2015

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      The 74th Annual Meeting of the Japanese Cancer Association.
    • Place of Presentation
      名古屋国際会議場(名古屋市)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-15K18414
  • [Presentation] HTLV-1感染T細胞株における恒常的IRF-5発現.2013

    • Author(s)
      石川千恵, 森直樹.
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] PP2AはATLの治療標的分子か?2013

    • Author(s)
      森直樹, 石川千恵.
    • Organizer
      第6回HTLV-1研究会
    • Place of Presentation
      東京大学医科学研究所講堂(東京)
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] HTLV-1感染T細胞株における恒常的IRF5発現.2013

    • Author(s)
      石川千恵, 森直樹.
    • Organizer
      第61回日本ウイルス学会学術集会
    • Place of Presentation
      神戸国際会議場(神戸)
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] Protein phosphatase 2A as a potential target for treatment of adult T cell leukemia.2013

    • Author(s)
      Mori N, Ishikawa C.
    • Organizer
      第75回日本血液学会学術集会
    • Place of Presentation
      ロトイン札幌(札幌)
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] Epstein-Barr virus latent membrane protein-1- and CD30-incuced IκB-ζ

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] PKC-δ activation in HTLV-1-infected T cells.

    • Author(s)
      Naoki Mori, Chie Ishikawa.
    • Organizer
      第76回日本血液学会学術集会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2014-10-31 – 2014-11-02
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] フラボノイド類化合物ブテインの抗成人T細胞白血病効果

    • Author(s)
      石川千恵、森直樹
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] Anti-adult T-cell leukemia effects of natural flavonoid, butein.

    • Author(s)
      Chie Ishikawa, Naoki Mori.
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] フラボノイド類化合物ブテインの抗成人T細胞白血病効果

    • Author(s)
      森直樹、石川千恵
    • Organizer
      第1回日本HTLV-1学会学術集会
    • Place of Presentation
      東京大学医科学研究所講堂(東京都港区)
    • Year and Date
      2014-08-22 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-25830085
  • [Presentation] EBウイルスLMP-1タンパク質によるNF-κB制御因子IκB-ζの発現誘導

    • Author(s)
      森直樹、石川千恵
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-11-10 – 2014-11-12
    • Data Source
      KAKENHI-PROJECT-25830085
  • 1.  森 直樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 2.  千馬 正敬
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

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