nakatsukasa kunio 中務邦雄

… Alternative Names

NAKATSUKASA Kunio 中務邦雄

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Researcher Number	90547522
Other IDs	https://orcid.org/0000-0002-8894-051X
Affiliation (Current)	2025: 名古屋市立大学, 大学院理学研究科, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 名古屋市立大学, 大学院理学研究科, 教授 2023: 名古屋市立大学, 大学院理学研究科, 准教授 2019 – 2021: 名古屋市立大学, 大学院理学研究科, 准教授 2017 – 2019: 名古屋市立大学, 大学院システム自然科学研究科, 准教授 2016: 名古屋大学, 理学研究科, 講師 … More 2015: 名古屋大学, 理学(系)研究科(研究院), 講師 2013 – 2014: 名古屋大学, 理学(系)研究科(研究院), 助教 2010 – 2011: 名古屋大学, 理学研究科, 助教 2010: Nagoya University, 理学(系)研究科(研究院), 助教 2009: Nagoya University, 大学院・理学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Functional biochemistry / Basic Section 38060:Applied molecular and cellular biology-related / Transformative Research Areas, Section (III) / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Cell biology / Biological Sciences Except Principal Investigator Functional biochemistry
Keywords	Principal Investigator 小胞体 / ユビキチン / 膜タンパク質 / 分解 / 出芽酵母 / 品質管理機構 / タンパク質分解 / タンパク質 / 代謝 / プロテアソーム … More / 品質管理 / 代謝制御 / ミトコンドリア / 栄養応答 / タンパク質寿命 / 微生物 / 脂肪滴 / リボソーム / ステロール / 解糖系 / 代謝酵素 / トリアシルグリセロール / リポリシス / 炭素代謝系 / ERAD / 金属イオン輸送体 / 生体膜 / タンパク質複合体 / ユビキチンリガーゼ / 構造 / 光架橋 … More Except Principal Investigator タンパク質分解 / ユビキチン / 転写因子 / ストレス応答 Less

タンパク質半減期の網羅測定を軸とした細胞の栄養応答・適応機構の解析Principal Investigator
- Principal Investigator
  
  中務邦雄
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nagoya City University
微生物におけるユビキチン修飾を介した脂質代謝・エネルギー代謝のストレス応答機構Principal Investigator
- Principal Investigator
  
  中務邦雄
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Nagoya City University
Environmental response mechanism of carbon metabolic system via ubiquitin modificationPrincipal Investigator
- Principal Investigator
  
  Nakatsukasa Kunio
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Nagoya City University
Genetic and biochemical analysis of the ER quality control of membrane proteinsPrincipal Investigator
- Principal Investigator
  
  Nakatsukasa Kunio
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Nagoya City University
Elucidation of novel function of Saccharomyces cerevisiae SCF complex
- Principal Investigator
  
  Kamura Takumi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Analysis of budding yeast E3 ubiquitin ligases that regulate the degradation of short life protein
- Principal Investigator
  
  Kamura Takumi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Physiological roles of ER-associated degradation beyond the protein quality controlPrincipal Investigator
- Principal Investigator
  
  Nakatsukasa Kunio
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
Analysis of a dynamic behavior of the E3 ubiquitin ligase in the endoplasmic reticulumPrincipal Investigator
- Principal Investigator
  
  NAKATSUKASA Kunio
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Nagoya University
試験管内アッセイ系による小胞体膜タンパク質の逆行輸送メカニズムの解明Principal Investigator
- Principal Investigator
  
  中務邦雄
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
In vivo site-sp ecific cross-linking analysis of substrate recognition mechanisms of membrane-associated E3 ligase enzymesPrincipal Investigator
- Principal Investigator
  
  NAKATSUKASA Kunio
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University
試験管内アッセイ系を用いたERAD(小胞体関連分解)の解析Principal Investigator
- Principal Investigator
  
  中務邦雄
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Functional biochemistry
- Research Institution
  Nagoya University

[Book] 実験医学2011年増刊2011
- Author(s)
  中務邦雄嘉村巧
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22657034
[Book] 実験医学2011年増刊(103-107ページ)2011
- Author(s)
  中務邦雄, 嘉村巧
- Total Pages
  241
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22657034
[Journal Article] Metabolomics analysis of an AAA-ATPase Cdc48-deficient yeast strain2023
- Author(s)
  Kawarasaki Tomoyuki、Nakatsukasa Kunio
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 2 Pages: e13219-e13219
- DOI
  10.1016/j.heliyon.2023.e13219
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H02923
[Journal Article] A positive genetic selection for transmembrane domain mutations in HRD1 underscores the importance of Hrd1 complex integrity during ERAD2022
- Author(s)
  Nakatsukasa Kunio、Wigge Sylvia、Takano Yuki、Kawarasaki Tomoyuki、Kamura Takumi、Brodsky Jeffrey L.
- Journal Title
  
  Current Genetics
  
  Volume: 68 Issue: 2 Pages: 227-242
- DOI
  10.1007/s00294-022-01227-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-19H02923
[Journal Article] Dot6/Tod6 degradation fine-tunes the repression of ribosome biogenesis under nutrient-limited conditions2022
- Author(s)
  Kusama Kino、Suzuki Yuta、Kurita Ena、Kawarasaki Tomoyuki、Obara Keisuke、Okumura Fumihiko、Kamura Takumi、Nakatsukasa Kunio
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 3 Pages: 103986-103986
- DOI
  10.1016/j.isci.2022.103986
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-19H02923
[Journal Article] Triacylglycerol lipase Tgl4 is a stable protein and its dephosphorylation is regulated in a cell cycle-dependent manner in Saccharomyces cerevisiae2022
- Author(s)
  Nakatsukasa Kunio、Fujisawa Munetaka、Yang Xiaotan、Kawarasaki Tomoyuki、Okumura Fumihiko、Kamura Takumi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 626 Pages: 85-91
- DOI
  10.1016/j.bbrc.2022.08.022
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-19H02923
[Journal Article] Proteolysis of adaptor protein Mmr1 during budding is necessary for mitochondrial homeostasis in Saccharomyces cerevisiae2022
- Author(s)
  Obara Keisuke、Yoshikawa Taku、Yamaguchi Ryu、Kuwata Keiko、Nakatsukasa Kunio、Nishimura Kohei、Kamura Takumi
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 1-15
- DOI
  10.1038/s41467-022-29704-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-19H02923
[Journal Article] Potential Physiological Relevance of ERAD to the Biosynthesis of GPI-Anchored Proteins in Yeast2021
- Author(s)
  Nakatsukasa K.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 22(3) Issue: 3 Pages: 1061-1061
- DOI
  10.3390/ijms22031061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-19H02923
[Journal Article] ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation2021
- Author(s)
  Okumura Fumihiko、Oki Nodoka、Fujiki Yuha、Ikuta Rio、Osaki Kana、Hamada Shun、Nakatsukasa Kunio、Hisamoto Naoki、Hara Taichi、Kamura Takumi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20880-20880
- DOI
  10.1038/s41598-021-00306-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-20H03208, KAKENHI-PROJECT-20H03408, KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-19H02923
[Journal Article] Cul5-type Ubiquitin Ligase KLHDC1 Contributes to the Elimination of Truncated SELENOS Produced by Failed UGA/Sec Decoding2020
- Author(s)
  Okumura Fumihiko、Fujiki Yuha、Oki Nodoka、Osaki Kana、Nishikimi Akihiko、Fukui Yoshinori、Nakatsukasa Kunio、Kamura Takumi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 3 Pages: 100970-100970
- DOI
  10.1016/j.isci.2020.100970
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06213, KAKENHI-PROJECT-19K06569, KAKENHI-PUBLICLY-19H04957, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-19H00983, KAKENHI-PROJECT-19H02923
[Journal Article] Msp1 Clears Mistargeted Proteins by Facilitating Their Transfer from Mitochondria to the ER2019
- Author(s)
  Matsumoto S., Nakatsukasa K., Kakuta C., Tamura Y., Esaki M., and *Endo T.
- Journal Title
  
  Molecular Cell
  
  Volume: 76 Issue: 1 Pages: 191-205
- DOI
  10.1016/j.molcel.2019.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-19H03174, KAKENHI-PROJECT-15H05705
[Journal Article] Harmonizing Experimental Data with Modeling to Predict Membrane Protein Insertion in Yeast2019
- Author(s)
  Guerriero C.J., Gomez Y.K., Daskivich G.J., Reutter K.R., Augustine A.A., Weiberth K.F., Nakatsukasa K., Grabe M., and *Brodsky J.L.
- Journal Title
  
  Biophysical Journal
  
  Volume: 117 Issue: 4 Pages: 668-678
- DOI
  10.1016/j.bpj.2019.07.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19306
[Journal Article] Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism2019
- Author(s)
  Sasako T., Ohsugi M., Kubota N., Itoh S., Okazaki Y, Terai A., Kubota T., Yamashita S., Nakatsukasa K., Kamura T., Iwayama K., Tokuyama K., Kiyonari H., Furuta Y., Shibahara J., Fukayama M., Enooku K., Okushin K., Tsutsumi T., Tateishi R., Tobe K., Asahara H., Koike K., *Kadowaki T. & *Ueki K.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41467-019-08591-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-18H02860
[Journal Article] Heterologous expression and functional analysis of the F-box protein Ucc1 from other yeast species in Saccharomyces cerevisiae2019
- Author(s)
  *Nakatsukasa K., Kawarasaki T., and Moriyama A.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 128 Issue: 6 Pages: 704-709
- DOI
  10.1016/j.jbiosc.2019.06.003
- NAID
  40022099990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02923
[Journal Article] The HECT-type ubiquitin ligase Tom1 contributes to the turnover of Spo12, a component of the FEAR network, in G2/M phase.2018
- Author(s)
  *Nakatsukasa K., Sone M., Alemayehu D.H., Okumura F., and *Kamura T.
- Journal Title
  
  FEBS Letters
  
  Volume: 592 Issue: 10 Pages: 1716-1724
- DOI
  10.1002/1873-3468.13066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19306, KAKENHI-PROJECT-17H03652
[Journal Article] Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.2017
- Author(s)
  1.Okumura, F., Joo-Okumura, A., Obara, K., Petersen, A., Nishikimi, A., Fukui, Y., Nakatsukasa, K., and Kamura, T
- Journal Title
  
  Mol Biol Cell
  
  Volume: 28 Issue: 24 Pages: 3532-3541
- DOI
  10.1091/mbc.e17-07-0450
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-17J40101, KAKENHI-PROJECT-15K21056
[Journal Article] Hypoxia-inducible factor-2α stabilizes the von Hippel-Lindau (VHL) disease suppressor, Myb-related protein 2.2017
- Author(s)
  Okumura F, Joo-Okumura A, Nakatsukasa K, Kamura T.
- Journal Title
  
  PLoS One
  
  Volume: 12(4):e0175593. Issue: 4 Pages: 1-10
- DOI
  10.1371/journal.pone.0175593
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21056, KAKENHI-PROJECT-17H03652, KAKENHI-PROJECT-17J40101
[Journal Article] The role of cullin 5-containing ubiquitin ligases2016
- Author(s)
  Okumura, F. , Joo-Okumura, A., Nakatsukasa, K. & Kamura, T.
- Journal Title
  
  Cell Division.
  
  Volume: N/A Issue: 1 Pages: 1-1
- DOI
  10.1186/s13008-016-0016-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21056, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-25291023, KAKENHI-PROJECT-15K18503
[Journal Article] Subcellular Fractionation Analysis of the Extraction of Ubiquitinated Polytopic Membrane Substrate during ER-Associated Degradation.2016
- Author(s)
  Nakatsukasa, K., Kamura, T
- Journal Title
  
  Plos one
  
  Volume: 11 Issue: 2 Pages: 1-17
- DOI
  10.1371/journal.pone.0148327
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14474, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-15K18503
[Journal Article] Parallel Regulation of von Hippel-Lindau Disease by pVHL-Mediated Degradation of B-Myb and Hypoxia-Inducible Factor α.2016
- Author(s)
  Okumura F, Uematsu K, Byrne SD, Hirano M, Joo-Okumura A, Nishikimi A, Shuin T, Fukui Y, Nakatsukasa K, Kamura T.
- Journal Title
  
  Molecular Cellular Biology
  
  Volume: 36 Issue: 12 Pages: 1803-1817
- DOI
  10.1128/mcb.00067-16
- NAID
  120005844088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01330, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-13J40160, KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503, KAKENHI-PROJECT-15K21056
[Journal Article] ASB7 regulates spindle dynamics and genome integrity by targeting DDA3 for proteasomal degradation.2016
- Author(s)
  Uematsu K, Okumura F, Tonogai S, Joo-Okumura A, Alemayehu DH, Nishikimi A, Fukui Y, Nakatsukasa K, Kamura T.
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 215 Issue: 1 Pages: 95-106
- DOI
  10.1083/jcb.201603062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01330, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503
[Journal Article] The ubiquitin ligase SCFUcc1 acts as a metabolic switch for the glyoxylate cycle.2015
- Author(s)
  Nakatsukasa, K., Nishimura, T., Byrne, D., Okamoto, M., Takahashi-Nakaguchi, A., Chibana, H., Okumura, F., Kamura, T.
- Journal Title
  
  Molecular Cell
  
  Volume: 59 Issue: 1 Pages: 22-34
- DOI
  10.1016/j.molcel.2015.04.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503, KAKENHI-PROJECT-15K21056, KAKENHI-PLANNED-24112006
[Journal Article] SCFUcc1ユビキチンリガーゼはグリオキシル酸回路の代謝スイッチとして機能する2015
- Author(s)
  Nakatsukasa, K. and Kamura T.
- Journal Title
  
  実験医学
  
  Volume: 33 Pages: 2613-2616
- Data Source
  KAKENHI-PROJECT-15K18503
[Journal Article] Proteolytic regulation of metabolic enzymes by E3 ubiquitin ligase complexes: lessons from yeast.2015
- Author(s)
  Nakatsukasa, K., Okumura, F., Kamura, T
- Journal Title
  
  Crit Rev Biochem Mol Biol.
  
  Volume: 50 Issue: 6 Pages: 489-502
- DOI
  10.3109/10409238.2015.1081869
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K14474, KAKENHI-PROJECT-15K18503, KAKENHI-PROJECT-15K21056, KAKENHI-PLANNED-24112006
[Journal Article] Recent technical developments in the study of ER-associated degradation.2014
- Author(s)
  Nakatsukasa, K., Kamura T., Brodsky, JL.
- Journal Title
  
  Current Opinion in Cell Biology
  
  Volume: 29 Pages: 82-91
- DOI
  10.1016/j.ceb.2014.04.008
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-25870312
[Journal Article] The nutrient stress-induced small GTPase Rab5 contributes to the activation of vesicle trafficking and vacuolar activity.2014
- Author(s)
  Nakatsukasa, K., Kanada, A., Matsuzaki, M., Byrne, SD., Okumura, F., Kamura, T.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Issue: 30 Pages: 20970-20978
- DOI
  10.1074/jbc.m114.548297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-25870312
[Journal Article] A stalled retrotranslocation complex reveals physical linkage between substrate recognition and proteasomal degradation during ER associated degradation2013
- Author(s)
  Kunio Nakatsukasa. Jeffrey L. Brodsky, Takumi Kamura
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: (印刷中) Issue: 11 Pages: 1765-1775
- DOI
  10.1091/mbc.e12-12-0907
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020017, KAKENHI-PROJECT-22370051, KAKENHI-PROJECT-23657088, KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-25291023, KAKENHI-PROJECT-25870312
[Journal Article] Regulation of cellular functions by Elongin BC based E3 ubiquitin ligase2013
- Author(s)
  Okumura F, Okumura A, Nakatsukasa K, Kamura T.
- Journal Title
  
  Seikagaku
  
  Volume: 85 Pages: 76-88
- NAID
  10031156446
- Data Source
  KAKENHI-PUBLICLY-22020017
[Journal Article] The Role of Elongin BC-Containing Ubiquitin Ligases.2012
- Author(s)
  Fumihiko Okumura, Mariko Matsuzaki, Kunio Nakatsukasa, Takumi Kamura
- Journal Title
  
  Regulation of cellular functions by Elongin BC based E3 ubiquitin ligase
  
  Volume: 2 Pages: 1-13
- DOI
  10.3389/fonc.2012.00010
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020017, KAKENHI-PROJECT-22370051, KAKENHI-PUBLICLY-23117501, KAKENHI-PROJECT-23657088
[Journal Article] Non-SCF type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function.2011
- Author(s)
  Liu Y, Nakatsukasa K, Kotera M, Kanada A, Nishimura T, Kishi T, Mimura S, Kamura T
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 印刷中(未定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657034
[Journal Article] Non-SCF type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function.2011
- Author(s)
  Liu Y, Nakatsukasa K, Kotera M, Kanada A, Nishimura T, Kishi T, Mimura S, Kamura T
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: (印刷中未定)
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22020017
[Journal Article] Non-SCF type F-box protein Roy1/Ymr258c interacts with a Rab5-like GTPase Ypt52 and inhibits Ypt52 function2011
- Author(s)
  Liu Y, Nakatsukasa K, Kotera M, Kanada A, Nishimura T, Kishi T, Mimura S, Kamura T
- Journal Title
  
  Molecular Biology of the Cell
  
  Volume: 22 Pages: 1575-1584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Excess non-imported mitochondrial metabolic enzyme elicits ectopic metabolic stress2022
- Author(s)
  川原崎智之、西尾和也、杉浦悠毅、此島彩乃、水島恒裕、中務邦雄
- Organizer
  第74回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] Accumulation of non-imported mitochondrial metabolic enzyme elicits ectopic metabolic stress2022
- Author(s)
  中務邦雄
- Organizer
  第15回小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] モデル基質を用いた核膜孔複合体の品質管理機構の解析2022
- Author(s)
  池田貴成、中務邦雄
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] Defective import of mitochondrial metabolic enzyme elicits ectopic metabolic stress2022
- Author(s)
  川原崎智之、西尾和也、杉浦悠毅、此島彩乃、水島恒裕、中務邦雄
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] 細胞質に蓄積したミトコンドリア代謝酵素によって引き起こされる異所性代謝ストレス2022
- Author(s)
  中務邦雄
- Organizer
  第74回日本生物工学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] Quality control of enzymatically active mitochondrial precursor protects cells against ectopic metabolite stress2021
- Author(s)
  中務邦雄
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] Quality control of enzymatically active mitochondrial precursor protects cells against ectopic metabolite stress2021
- Author(s)
  中務邦雄
- Organizer
  第73回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] 細胞質に誤局在したクエン酸合成酵素の分解による代謝恒常性の維持2020
- Author(s)
  中務邦雄
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] Maintenance of metabolic homeostasis by the proteasomal degradation of cytosolically mislocalized citrate synthase.2020
- Author(s)
  川原﨑智之, 中務邦雄
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] 細胞質に誤局在したクエン酸合成酵素の分解による代謝恒常性の維持2020
- Author(s)
  中務邦雄
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] A possible novel mechanism for the regulation of ribosome biogenesis under starvation conditions2020
- Author(s)
  草間幾乃, 中務邦雄
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] A possible novel mechanism for the regulation of ribosome biogenesis under starvation conditions2020
- Author(s)
  草間幾乃, 中務邦雄
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] Maintenance of metabolic homeostasis by the proteasomal degradation of cytosolically mislocalized citrate synthase.2020
- Author(s)
  川原﨑智之, 中務邦雄
- Organizer
  第72回日本細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-19H02923
[Presentation] ＨＩＦ-２alphaによるフォン・ヒッペル・リンドウ病抑制因子Ｂ－Ｍｙｂの安定化2019
- Author(s)
  奥村文彦, 奥村晶子, 中務邦雄, 嘉村巧
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 栄養ストレス条件下におけるリボソーム生合成の調節機構2019
- Author(s)
  中務邦雄
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] Regulation of metabolic pathways by the ubiquitin-proteasome system2018
- Author(s)
  Kunio Nakatsukasa
- Organizer
  International Symposium - Proteins: From the Cradle to the Grave
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] 出芽酵母E3リガーゼ複合体SCFMet30によるAry34の分解制御2018
- Author(s)
  山口竜, 小原圭介, 奥村文彦, 嘉村巧, 中務邦雄
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母E3リガーゼ複合体SCFMet30によるAry34の分解制御2018
- Author(s)
  〇山口竜1、小原圭介1、奥村文彦1、嘉村巧1、中務邦雄2
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] 可溶性の代謝酵素の分解におけるAAA ATPase Cdc48/p97の役割2018
- Author(s)
  川原﨑智之2、森山昭彦2、〇中務邦雄1
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] ２つのAAA-ATPアーゼによるミトコンドリア外膜に誤局在したテイルアンカータンパク質の分解機構2018
- Author(s)
  〇松本俊介1、角田千香1、中務邦雄2、田村康3、江崎雅俊4、遠藤斗志也1
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] 小胞体および小胞体から形成される膜系を舞台とした膜タンパク質の分解経路2018
- Author(s)
  〇中務邦雄
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] ユビキチンリガーゼSPSB4はEphB2を介した細胞間反発運動を抑制する2018
- Author(s)
  〇奥村文彦1、奥村（城尾）晶子1、小原圭介1、錦見昭彦3、福井宣規2、中務邦雄4、嘉村巧1
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K19306
[Presentation] 出芽酵母E3リガーゼSCFMet30によるAry34の分解制御機構の解析2017
- Author(s)
  山口竜、中務邦雄、奥村文彦、小原圭介、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] ユビキチンリガーゼASB7によるDDA3の発現制御は、適切な紡錘体形成と染色体分配に必要である2017
- Author(s)
  奥村文彦、植松桂司、外海駿輔、奥村(城尾) 晶子、Alemayehu Dawit、錦見昭彦、福井宣規、中務邦雄、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Invited
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] pVHL依存的なB-MybとHIFαの分解はそれぞれ独立してVHL病を制御している2017
- Author(s)
  奥村文彦, 植松桂司, Byrne STUART D., 平野みえ, 奥村(城尾) 晶子, 錦見昭彦, 執印太郎, 福井宣規, 中務邦雄, 嘉村巧
- Organizer
  日本薬学会第１３７年会
- Place of Presentation
  東北大学、仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] リボソーム生合成を負に制御するDot6とTod6は飢餓条件においてプロテアソーム依存的に分解される2017
- Author(s)
  鈴木優太、中務邦雄、小原圭介、奥村文彦、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母トリアシルグリセロールリパーゼの制御メカニズムの解析2017
- Author(s)
  藤澤宗隆、中務邦雄、小原圭介、奥村文彦、嘉村巧
- Organizer
  2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17H03652
[Presentation] 出芽酵母E3リガーゼSCFDia2の新奇基質Prl1の同定2016
- Author(s)
  Dawit Hailu Alemayehu1、中務邦雄1、奥村文彦1、嘉村巧1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] 出芽酵母E3リガーゼSCFDia2の新奇基質Prl1の同定2016
- Author(s)
  Alemayehu Dawit Hailu、中務邦雄、奥村文彦、嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] ユビキチンリガーゼASB7によるDDA3の発現制御は適切な紡錘体形成と染色体分配に必要である2016
- Author(s)
  奥村文彦1、植松桂司1、外海駿輔1、奥村（城尾）晶子1、Dawit Hailu Alemayehu1、錦見昭彦2、福井宣規2、中務邦雄1、嘉村巧1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] 出芽酵母タンパク質BDF2の機能解析2016
- Author(s)
  大谷悠貴、中務邦雄、奥村文彦、嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] ユビキチンリガーゼASB7によるDDA3の発現制御は適切な紡錘体形成と染色体分配に必要である2016
- Author(s)
  奥村文彦、植松桂司、外海　駿輔、奥村(城尾) 晶子、Alemayehu Dawit Hailu、錦見昭彦、福井宣規、中務邦雄、嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] クエン酸合成酵素Cit2およびリガンド複合体の結晶構造解析2016
- Author(s)
  森山周1、西尾和也1、中務邦雄2、嘉村巧2、水島恒裕1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] リボソーム生合成を負に調節する転写制御因子Dot6およびTod6は窒素源飢餓条件でプロテアソーム依存的に分解される2016
- Author(s)
  鈴木優太、栗田英奈、中務邦雄、奥村文彦、嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] 出芽酵母におけるトリアシルグリセロールリパーゼの活性制御機構の解析2016
- Author(s)
  藤澤宗隆1、中務邦雄1、奥村文彦1、嘉村巧1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] The Ubiquitin Ligase SCFUcc1 Acts as a Metabolic Switch for the Glyoxylate Cycle2016
- Author(s)
  中務　邦雄、嘉村　巧
- Organizer
  ICY14 (The 14th International Congress on Yeasts)
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] 出芽酵母タンパク質Bdf2の機能解析2016
- Author(s)
  大谷悠貴1、中務邦雄1、奥村文彦1、嘉村巧1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] 出芽酵母E3リガーゼ複合体SCFMet30によるAry34の分解制御2016
- Author(s)
  山口竜1、中務邦雄1、奥村文彦1、嘉村巧1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] F-boxタンパク質Ucc1によるクエン酸合成酵素Cit2の認識機構2016
- Author(s)
  西尾和也1、森山周1、中務邦雄2、嘉村巧2、水島恒裕1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] 出芽酵母におけるトリアシルグリセロールリパーゼの活性制御機構の解析2016
- Author(s)
  藤澤宗隆、中務邦雄、奥村文彦、嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] 出芽酵母E3リガーゼ複合体SCFMet30によるAry34の分解制御2016
- Author(s)
  山口竜、中務邦雄、奥村文彦、嘉村巧
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] リボソーム生合成を負に調節する転写制御因子Dot6およびTod6は窒素源飢餓条件でプロテアソーム依存的に分解される2016
- Author(s)
  鈴木優太1、栗田英奈1、中務邦雄1、奥村文彦1、嘉村巧1
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] 出芽酵母E3リガーゼSCFDia2の新奇基質Prl1の同定2015
- Author(s)
  Dawit Hailu Alemayehu、中務邦雄、奥村文彦、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] Fボックスタンパク質Ucc1による代謝制御機構の解析2015
- Author(s)
  中務邦雄、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] ユビキチンリガーゼSCFMet30の新規基質p17の同定と機能解析2015
- Author(s)
  富澤優貴、中務邦雄、奥村文彦、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] 染色体安定性の維持におけるCRL5ASB7ユビキチンリガーゼの機能2015
- Author(s)
  植松桂司、奥村文彦、中務邦雄、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] pVHL依存的なFOBとHIFαの分解はそれぞれ独立してVHL病を制御している2015
- Author(s)
  奥村文彦、植松桂司、Stuart D. Byrne、平野みえ、奥村(城尾) 晶子、錦見昭彦、執印太郎、福井宣規、中務邦雄、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] Hect型E3リガーゼTom1によるFEARネットワーク構成因子Spol2の分解制御2015
- Author(s)
  栗田英奈、中務邦雄、曽根恵、奥村文彦、嘉村巧
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K14474
[Presentation] Fボックスタンパク質Ucc1による代謝制御機構の解析2015
- Author(s)
  中務邦雄
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K18503
[Presentation] The dynamic and controlled assembly of the Hrdl ubiquitin ligase complex is essential to maintain ER homeostasis2012
- Author(s)
  Kunio Nakatsukasa, Jeffrey L. Brodsky, Takumi Kamura
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PUBLICLY-22020017
[Presentation] ERADにおける小胞体膜ユビキチンリガーゼ複合体の機能解析2011
- Author(s)
  Nakatsukasa K, and Kamura T
- Organizer
  第11回蛋白質科学会年会(招待講演)
- Place of Presentation
  大阪
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] ERADにおける小胞体膜ユビキチンリガーゼ複合体の機能解析2011
- Author(s)
  Nakatsukasa K, Kamura T
- Organizer
  第11回蛋白質科学会年会
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2011-06-07
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Molecular dissection of the ER-associated degradation2011
- Author(s)
  Nakatsukasa K
- Organizer
  Global COE Mini-symposium : Toward Systems Glycobiology-Biosynthesis and catabolism of glycoproteins
- Place of Presentation
  名古屋
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Molecular dissection of the ER-associated degradation2011
- Author(s)
  Nakatsukasa K
- Organizer
  Global COE Mini-symposium : Toward Systems Glycobiology-Biosynthesis and catabolism of glycoproteins
- Place of Presentation
  名古屋(招待講演)
- Year and Date
  2011-11-07
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Regulatory mechanisms for the membrane extraction of ERAD substrates at a post-ubiquitination step2010
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  BMB2010
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Regulatory mechanisms for the membrane extraction of ERAD substrates at a post-ubiquitination step2010
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  BMB2010
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-22020017
[Presentation] Regulatory mechanisms for the membrane extraction of ERAD substrates at a post-ubiquitination step2010
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  特定領域研究・タンパク質分解班会議
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Regulatory mechanisms for the membrane extraction of ERAD substrates at a post-ubiquitination step2010
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  特定領域研究・タンパク質社会国際班会議
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-22657034
[Presentation] Regulatory mechanisms for the membrane extraction of ERAD substrates at a post-ubiquitination step2010
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  特定領域研究・タンパク質分解班会議
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-22020017
[Presentation] Regulatory mechanisms for the membrane extraction of ERAD substrates at a post-ubiquitination step2010
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  特定領域研究・タンパク質社会国際班会議
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PUBLICLY-22020017
[Presentation] 膜タンパク質の小胞体関連分解(ERAD)の生化学および遺伝学的手法による解析2009
- Author(s)
  中務邦雄・嘉村巧
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21870013
[Presentation] Subcellular fractionation analysis of the extraction of ubiquitinated polytopic substrates during ER-associated degradation
- Author(s)
  Nakatsukasa K., Kamura T.
- Organizer
  American Society for Cell Biology
- Place of Presentation
  フィラデルフィア
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-25870312

1. Kamura Takumi (40333455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 26 results
2. 奥村文彦 (00507212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
3. 錦見昭彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

nakatsukasa kunio 中務 邦雄

NAKATSUKASA Kunio 中務 邦雄

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タンパク質半減期の網羅測定を軸とした細胞の栄養応答・適応機構の解析Principal Investigator

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微生物におけるユビキチン修飾を介した脂質代謝・エネルギー代謝のストレス応答機構Principal Investigator

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Environmental response mechanism of carbon metabolic system via ubiquitin modificationPrincipal Investigator

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Genetic and biochemical analysis of the ER quality control of membrane proteinsPrincipal Investigator

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Elucidation of novel function of Saccharomyces cerevisiae SCF complex

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Analysis of budding yeast E3 ubiquitin ligases that regulate the degradation of short life protein

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Physiological roles of ER-associated degradation beyond the protein quality controlPrincipal Investigator

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Analysis of a dynamic behavior of the E3 ubiquitin ligase in the endoplasmic reticulumPrincipal Investigator

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試験管内アッセイ系による小胞体膜タンパク質の逆行輸送メカニズムの解明Principal Investigator

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In vivo site-sp ecific cross-linking analysis of substrate recognition mechanisms of membrane-associated E3 ligase enzymesPrincipal Investigator

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試験管内アッセイ系を用いたERAD(小胞体関連分解)の解析Principal Investigator

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[Book] 実験医学2011年増刊2011

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[Book] 実験医学2011年増刊(103-107ページ)2011

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nakatsukasa kunio 中務邦雄

NAKATSUKASA Kunio 中務邦雄