• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Maezawa So  前澤 創

Researcher Number 90548174
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-9060-2042
Affiliation (Current) 2025: 東京理科大学, 創域理工学部生命生物科学科, 教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 東京理科大学, 創域理工学部生命生物科学科, 准教授
2021 – 2023: 東京理科大学, 理工学部応用生物科学科, 准教授
2018 – 2019: 麻布大学, 獣医学部, 講師
Review Section/Research Field
Principal Investigator
Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Transformative Research Areas, Section (III) / Basic Section 42030:Animal life science-related / Biological Sciences / 0702:Biology at cellular to organismal levels, and related fields
Except Principal Investigator
Basic Section 46010:Neuroscience-general-related / Transformative Research Areas, Section (III)
Keywords
Principal Investigator
エピゲノム / 生殖科学 / 精子形成 / クロマチン / エピジェネティクス / 生殖細胞 / 分化 / 減数分裂 / 分化誘導 / エピゲノム編集 … More / 配偶子形成 / 性染色体 / 核ラミナ / 栄養 / 発生分化 / 発生 / メタボローム / 代謝 / 分化運命 / パイオニア因子 / 転写因子 / ATAC-seq / RNA-seq / A-MYB / エンハンサー … More
Except Principal Investigator
CAPSタンパク質 / 分泌障害 / 有芯小胞 / 開口放出 / アミラーゼ / 分泌顆粒 / Cadps2 / CAPS2 / 腺房細胞 / 膵外分泌 / ドーパミン / 中脳黒質緻密部 / 中脳被蓋野 / 慢性膵炎 / 膵腺房細胞 / エキソサイトーシス / 分泌小胞 / CAPS2/CADPS2 / エピゲノム / 栄養 / 代謝 / ライフスパン / 生殖細胞 Less
  • Research Projects

    (7 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (8 People)
  •  Multimodal regulation of chromatin structure during mouse spermatogenesisPrincipal Investigator

    • Principal Investigator
      前澤 創
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tokyo University of Science
  •  Metabolic regulation of reproductive lifespan

    • Principal Investigator
      林 陽平
    • Project Period (FY)
      2023 – 2027
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tohoku University
  •  単一細胞クロマチン接近性解析に基づいた、エピゲノム編集による配偶子形成制御Principal Investigator

    • Principal Investigator
      前澤 創
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 42:Veterinary medical science, animal science, and related fields
    • Research Institution
      Tokyo University of Science
  •  The role of CAPS in the activity-dependent dense-core vesicle exocytosis: function and impairment

    • Principal Investigator
      古市 貞一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46010:Neuroscience-general-related
    • Research Institution
      Tokyo University of Science
  •  Regulation of cell fate decision during mammalian spermatogenesisPrincipal Investigator

    • Principal Investigator
      前澤 創
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo University of Science
  •  Interplay between epigenetics and metabolism in transgenerational inheritancePrincipal Investigator

    • Principal Investigator
      Maezawa So
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42030:Animal life science-related
    • Research Institution
      Tokyo University of Science
  •  Establishment of germline-specific epigenome in mouse spermatogenesisPrincipal Investigator

    • Principal Investigator
      Maezawa So
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0702:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Azabu University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] CTCF-mediated 3D chromatin predetermines the gene expression program in the male germline2023

    • Author(s)
      Kitamura Yuka、Takahashi Kazuki、Maezawa So、Munakata Yasuhisa、Sakashita Akihiko、Kaplan Noam、Namekawa Satoshi H.
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2023.11.30.569508

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18084, KAKENHI-PUBLICLY-22H04700, KAKENHI-PROJECT-21H02383
  • [Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023

    • Author(s)
      Sakashita Akihiko、Ooga Masatoshi、Otsuka Kai、Maezawa So、Takeuchi Chikara、Wakayama Sayaka、Wakayama Teruhiko、Namekawa Satoshi?H
    • Journal Title

      Nucleic Acids Research

      Volume: 51 Issue: 13 Pages: 6668-6683

    • DOI

      10.1093/nar/gkad479

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18084, KAKENHI-PUBLICLY-22H04700, KAKENHI-PROJECT-21H02383
  • [Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023

    • Author(s)
      *Sakashita A, Ooga M, Otsuka K, Maezawa S, Takeuchi C, Wakayama S, Wakayama T, and *Namekawa SH
    • Journal Title

      Nucleic Acids Research

      Volume: in press

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02383
  • [Journal Article] KRAB-zinc-finger proteins regulate endogenous retroviruses to sculpt germline transcriptomes and genome evolution2023

    • Author(s)
      Otsuka Kai、Sakashita Akihiko、Maezawa So、Schultz Richard M.、Namekawa Satoshi H.
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2023.06.24.546405

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18084, KAKENHI-PUBLICLY-22H04700, KAKENHI-PROJECT-21H02383
  • [Journal Article] PRC1 directs PRC2-H3K27me3 deposition to shield adult spermatogonial stem cells from differentiation2023

    • Author(s)
      Hu Mengwen、Yeh Yu-Han、Maezawa So、Nakagawa Toshinori、Yoshida Shosei、Namekawa Satoshi?H
    • Journal Title

      Nucleic Acids Research

      Volume: 52 Issue: 5 Pages: 2306-2322

    • DOI

      10.1093/nar/gkad1203

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18084, KAKENHI-PLANNED-18H05551, KAKENHI-PROJECT-23H00380, KAKENHI-PROJECT-21H02383
  • [Journal Article] Polycomb protein SCML2 mediates paternal epigenetic inheritance through sperm chromatin2023

    • Author(s)
      *Sakashita A, Ooga M, Otsuka K, Maezawa S, Takeuchi C, Wakayama S, Wakayama T, and *Namekawa SH
    • Journal Title

      Nucleic Acids Research

      Volume: in press

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Journal Article] PRC1 suppresses a female gene regulatory network to ensure testicular differentiation2023

    • Author(s)
      Maezawa So、Yukawa Masashi、Hasegawa Kazuteru、Sugiyama Ryo、Iizuka Mizuho、Hu Mengwen、Sakashita Akihiko、Vidal Miguel、Koseki Haruhiko、Barski Artem、DeFalco Tony、Namekawa Satoshi H.
    • Journal Title

      Cell Death & Disease

      Volume: 14 Issue: 8

    • DOI

      10.1038/s41419-023-05996-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18084, KAKENHI-PLANNED-19H05745, KAKENHI-PUBLICLY-22H04700, KAKENHI-PROJECT-21H02383
  • [Journal Article] PRC1-mediated epigenetic programming is required to generate the ovarian reserve2022

    • Author(s)
      Hu Mengwen、Yeh Yu-Han、Munakata Yasuhisa、Abe Hironori、Sakashita Akihiko、Maezawa So、Vidal Miguel、Koseki Haruhiko、Hunter Neil、Schultz Richard M.、Namekawa Satoshi H.
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1

    • DOI

      10.1038/s41467-022-31759-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02383, KAKENHI-PROJECT-21K15108, KAKENHI-PLANNED-19H05745, KAKENHI-PUBLICLY-21H00233, KAKENHI-PUBLICLY-22H04700
  • [Journal Article] Bioinformatics Pipelines for Identification of Super-Enhancers and 3D Chromatin Contacts2022

    • Author(s)
      Sakashita Akihiko、Takeuchi Chikara、Maezawa So、Namekawa Satoshi H.
    • Journal Title

      Methods Mol. Biol.

      Volume: 2577 Pages: 123-146

    • DOI

      10.1007/978-1-0716-2724-2_9

    • ISBN
      9781071627235, 9781071627242
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02383, KAKENHI-PROJECT-22KJ2696, KAKENHI-PUBLICLY-21H00233, KAKENHI-PUBLICLY-22H04700
  • [Journal Article] Loss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice2022

    • Author(s)
      Sato Y、Tsuyusaki M、Takahashi-Iwanaga H、Fujisawa R、Masamune A、Hamada S、Matsumoto R、Tanaka Y、Kakuta Y、Yamaguchi-Kabata Y、Furuse T、Wakana S、Shimura T、Kobayashi R、Shinoda Y、Goitsuka R、Maezawa S、Sadakata T、Sano Y、Furuichi T
    • Journal Title

      Frontiers in Molecular Biosciences

      Volume: 9 Pages: 1-18

    • DOI

      10.3389/fmolb.2022.1040237

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07236, KAKENHI-PROJECT-22K06447, KAKENHI-PROJECT-21H02372, KAKENHI-PUBLICLY-21H05611, KAKENHI-PROJECT-23K23977
  • [Journal Article] ATAC-Seq Analysis of Accessible Chromatin: From Experimental Steps to Data Analysis2022

    • Author(s)
      Tatara Mayu、Ikeda Taiyo、Namekawa Satoshi H.、Maezawa So
    • Journal Title

      Methods Mol. Biol.

      Volume: 2577 Pages: 65-81

    • DOI

      10.1007/978-1-0716-2724-2_5

    • ISBN
      9781071627235, 9781071627242
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02383, KAKENHI-PUBLICLY-21H00233
  • [Journal Article] Use of Visual Information by Ant Species Occurring in Similar Urban Anthropogenic Environments2022

    • Author(s)
      Notomi Yusuke、Kazawa Tomoki、Maezawa So、Kanzaki Ryohei、Haupt Stephan Shuichi
    • Journal Title

      Zoological Science

      Volume: 39 Issue: 6 Pages: 529-544

    • DOI

      10.2108/zs220035

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02383, KAKENHI-PUBLICLY-21H00233
  • [Journal Article] Meiotic sex chromosome inactivation and the XY body: a phase separation hypothesis2021

    • Author(s)
      Alavattam Kris G.、Maezawa So、Andreassen Paul R.、Namekawa Satoshi H.
    • Journal Title

      Cellular and Molecular Life Sciences

      Volume: 79 Issue: 1

    • DOI

      10.1007/s00018-021-04075-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H00233, KAKENHI-PROJECT-21H02383
  • [Journal Article] Endogenous retroviruses drive species-specific germline transcriptomes in mammals2020

    • Author(s)
      Sakashita Akihiko、Maezawa So、Alavattam Kris G.、Yukawa Masashi、Barski Artem、Pavlicev Mihaela、Namekawa Satoshi H.
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2020.03.11.987230

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K21196
  • [Journal Article] Super-enhancer switching drives a burst in germline gene expression at the mitosis-to-meiosis transition2020

    • Author(s)
      Maezawa So、Yukawa Masashi、Chen Xiaoting、Sakashita Akihiko、Alavattam Kris G.、Weirauch Matthew T.、Barski Artem、Namekawa Satoshi H.
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2020.03.11.987180

    • Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K21196
  • [Presentation] マウス精子形成期におけるエピゲノムおよびクロマチン制御機構2023

    • Author(s)
      前澤創
    • Organizer
      第3回有性生殖研究会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] マウス精子形成期におけるエピゲノムおよびクロマチン制御機構2023

    • Author(s)
      前澤創
    • Organizer
      第3回有性生殖研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02383
  • [Presentation] Dynamic nuclear lamina-chromatin interactions during spermatogenesis2022

    • Author(s)
      前澤創
    • Organizer
      The International Symposium "Totipotency and Germ Cell Development"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] 生命の連続性を担う、生殖細胞のエピゲノム形成機構2022

    • Author(s)
      前澤創
    • Organizer
      日本医科大学・東京理科大学 第9回合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] マウス精子形成過程における分化運命決定機構の解明2022

    • Author(s)
      前澤創
    • Organizer
      NGS EXPO 2022
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] Dynamic nuclear lamina-chromatin interactions during spermatogenesis2022

    • Author(s)
      前澤創
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-21H02383
  • [Presentation] Polycomb suppresses a female gene regulatory network in Sertoli cells2022

    • Author(s)
      前澤創
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] 生命の連続性を担う、生殖細胞のエピゲノム形成機構2022

    • Author(s)
      前澤創
    • Organizer
      日本医科大学・東京理科大学 第9回合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-21H02383
  • [Presentation] Polycomb suppresses a female gene regulatory network in Sertoli cells2022

    • Author(s)
      前澤創
    • Organizer
      第15回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-21H02383
  • [Presentation] Dynamic nuclear lamina-chromatin interactions during spermatogenesis2022

    • Author(s)
      前澤創
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] Dynamic nuclear lamina-chromatin interactions during spermatogenesis2022

    • Author(s)
      前澤創
    • Organizer
      The International Symposium "Totipotency and Germ Cell Development"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02383
  • [Presentation] 生命の連続性を担う生殖細胞のエピゲノム形成機構2021

    • Author(s)
      前澤創
    • Organizer
      第114回 日本繁殖生物学会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00233
  • [Presentation] 生命の連続性に迫るー生殖細胞のエピゲノム形成機構2019

    • Author(s)
      前澤創
    • Organizer
      形態解析ワークショップー多様な顕微鏡を用いて
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K21196
  • [Presentation] Super-enhancer switching drives a burst in germline gene expression at the mitosis-to-meiosis transition2019

    • Author(s)
      前澤創
    • Organizer
      EpiBio2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K21196
  • [Presentation] Super-enhancer switching drives a burst in germline gene expression at the mitosis-to-meiosis transition2019

    • Author(s)
      前澤創
    • Organizer
      第13回エピジェネティクス 研究会
    • Data Source
      KAKENHI-PROJECT-19K21196
  • [Presentation] マウス精子形成期におけるクロマチン構造変化による遺伝子発現制御機構2018

    • Author(s)
      前澤創
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K21196
  • [Presentation] Genome-wide establishment of meiotic super-enhancers drives expression of spermatogenesis- specific genes2018

    • Author(s)
      前澤創
    • Organizer
      3R&3C Symposium 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K21196
  • 1.  林 陽平 (00588056)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  大我 政敏 (40644886)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  平山 明由 (00572405)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  森 大 (00588981)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  古市 貞一 (50219094)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  篠田 陽 (80403096)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  定方 哲史 (90391961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  岩永 ひろみ
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi