Kozuma Yukinori 上妻行則

… Alternative Names

KOZUMA Yukinori 上妻行則

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Researcher Number	90550145
Affiliation (Current)	2025: 熊本保健科学大学, 保健科学部, 准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 熊本保健科学大学, 保健科学部, 准教授 2018 – 2021: 熊本保健科学大学, 保健科学部, 准教授 2011 – 2017: 筑波大学, 医学医療系, 助教 2009 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 助教
Review Section/Research Field	Principal Investigator Hematology / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55030:Cardiovascular surgery-related Except Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 54010:Hematology and medical oncology-related / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 血小板 / 巨核球 / 人工肺 / 体外循環 / 体外式膜型人工肺 / 止血 / 外科手術 / 血小板機能 / 止血薬 / 抗血小板薬 … More / 人工髄液 / 細胞周期 / apoptosis / Bim … More Except Principal Investigator CD42b / 肝細胞 / 脱シアル化血小板 / 血小板 / 発作性夜間ヘモグロビン尿症 / フィーダー細胞 / バイオリアクター / 細胞・組織 / 移植・再生医療 / ティッシュ・エンジニアリング / 共培養 / 三次元培養 / 分化・増殖 / 凍結保存 / さい帯血 / ストローマ細胞 / 造血幹細胞 Less

体外循環時に生じる人工肺内圧の上昇および術後出血を防止するための革新的戦略Principal Investigator
- Principal Investigator
  
  上妻行則
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kumamoto Health Science University
抗補体療法下の PNH 血小板異常と血栓メカニズムの解析
- Principal Investigator
  
  上野志貴子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kumamoto University
老化血小板を用いた肝疾患における新規治療法確立を目指した基礎研究
- Principal Investigator
  
  登尾一平
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto Health Science University
体外式膜型人工肺（ECMO）における血栓形成ゼロを目指した新たな制御戦略Principal Investigator
- Principal Investigator
  
  上妻行則
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto Health Science University
Development of the new hemostatic which is available by emergency surgery and the platelet agentPrincipal Investigator
- Principal Investigator
  
  Kozuma Yukinori
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto Health Science University
Ex vivo reconstruction of hematopoietic functions using three-dimensional freeze-thawed feeder cell layer
- Principal Investigator
  
  Hirotoshi Miyoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  University of Tsukuba
Systematic analysis of megakaryopoiesis and platelet functionPrincipal Investigator
- Principal Investigator
  
  Kozuma Yukinori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
Analysis of the molecular mechanism regulated during megakaryopoiesis and platelet functionPrincipal Investigator
- Principal Investigator
  
  KOZUMA Yukinori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba
Systematic analysis of megakaryopoiesis and platelet production by using genetically modified mice.Principal Investigator
- Principal Investigator
  
  KOZUMA Yukinori
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba

All 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

[Book] 若葉マーク臨床検査技師エッセンス・ノート2臨床形態検査、止血・凝固・線溶機構2013
- Author(s)
  編集:山内一由、分担:上妻行則
- Total Pages
  217
- Publisher
  メジカルビュー社
- Data Source
  KAKENHI-PROJECT-23791069
[Journal Article] 医療系大学の双方向型授業におけるインフルエンザ感染拡大のリスクと対策2021
- Author(s)
  山本隆敏、田邊香野、登尾一平、水本豪、川口辰哉、池田勝義、楢原真二、上妻行則
- Journal Title
  
  厚生の指標
  
  Volume: 68 Pages: 33-39
- NAID
  40022496682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation.2020
- Author(s)
  Furugaki T, Shigeta O, Kozuma Y, Tsukada T, Nakajima T, Sakamoto H,Mathis BJ, Hiramatsu Y, Suzuki Y.
- Journal Title
  
  Journal of
  
  Volume: －
- NAID
  120007169660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] 学内における交差混合試験理解のための Rivaroxaban の応用2020
- Author(s)
  登尾一平、山本隆敏、平野京介、佛淵悠大、渡邊一史、田邊香野、川口辰哉、上妻行則
- Journal Title
  
  熊本保健科学大学研究誌
  
  Volume: 17 Pages: 59-70
- NAID
  120006841028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] 巨核球造血におけるアポトーシス関連タンパクの役割2020
- Author(s)
  上妻行則、登尾一平
- Journal Title
  
  熊本保健科学大学研究誌
  
  Volume: 17 Pages: 1-9
- NAID
  40022193889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] 交差混合試験の新規実習教材の開発：直接経口抗凝固薬を用いたインヒビター疑似検体の可能性2019
- Author(s)
  登尾一平、山本隆敏、坂本亜理紗、田邊香野、川口辰哉、楢原真二、杉内博幸、上妻行則
- Journal Title
  
  臨床検査学教育
  
  Volume: 11 Pages: 175-181
- NAID
  40022025394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] Rivaroxaban は学内実習における交差混合試験の凝固因子インヒビターとして有用である2019
- Author(s)
  登尾一平、山本隆敏、上妻行則
- Journal Title
  
  熊本保健科学大学研究誌
  
  Volume: 16 Pages: 131-140
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] Stratifin inhibits SCFFBW7 formation and blocks ubiqutination of oncoproteins during the course of lung adenocartinogenesis.2019
- Author(s)
  1.Shiba-Ishi A, Hong J, Hirokawa T, Kim Y, Nakagawa T, Sakashita S, Sakamoto N, Kozuma Y, Sato Y, Noguchi M.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 25 Issue: 9 Pages: 2809-2820
- DOI
  10.1158/1078-0432.ccr-18-3631
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] calpain はがん転移における腫瘍細胞の遊走および浸潤に関与するが、腫瘍細胞によって誘導される血小板凝集には関与しない2019
- Author(s)
  上妻行則、田代ゆう子、登尾一平、二宮治彦
- Journal Title
  
  熊本保健科学大学研究誌
  
  Volume: 16 Pages: 17-28
- NAID
  120006631841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08587
[Journal Article] 血小板寿命とクリアランス2017
- Author(s)
  上妻行則
- Journal Title
  
  血液フロンティア
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-26860718
[Journal Article] Sodium bicarbonate facilitates hemostasis in the presence of cerebrospinal fluid through amplification of platelet aggregation.2016
- Author(s)
  Yukinori Kozuma, Tetsuya Yamamoto, Eiichi Ishikawa, Fumiyo Yoshida, Hiroyoshi Akutsu, Masahide Matsuda, Kei Nakai, Wataro Tsuruta, Shingo Takano, Akira Matsumura, Haruhiko Ninomiya
- Journal Title
  
  Neurosurgery
  
  Volume: 78 Issue: 2 Pages: 274-284
- DOI
  10.1227/neu.0000000000001058
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860718
[Journal Article] Clgalt1-deficient mice exhibit thrombocytopenia due to abnormal terminal differentiation of megakaryocytes2013
- Author(s)
  Kudo T, et al. (13人中8番目)
- Journal Title
  
  Blood
  
  Volume: 122 Issue: 9 Pages: 1649-1657
- DOI
  10.1182/blood-2012-12-471102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J00028, KAKENHI-PROJECT-23500488, KAKENHI-PROJECT-23791069, KAKENHI-PLANNED-24108006, KAKENHI-PROJECT-24241073, KAKENHI-PROJECT-24300152, KAKENHI-PROJECT-24590498, KAKENHI-PUBLICLY-25122702
[Journal Article] Human platelets promoto liver regenerartion with kupper cells in SCID mice.2013
- Author(s)
  Kazuhiro Takahashi, Yukinori Kozuma, Hidenori Suzuki, Takafumi Tamura, Takehito Maruyama, Kiyoshi Fukunaga, Soichiro Murata, Nobuhiro Ohkohchi
- Journal Title
  
  Journal of Surgical Research
  
  Volume: 180 Pages: 62-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791069
[Journal Article] Human platelets promote liver regeneration with kupffer cells in SCID mice2013
- Author(s)
  Takahashi K, Kozuma Y, Suzuki H, Tamura T, Maruyama T, Fukunaga K, Murata S, Ohkohchi N
- Journal Title
  
  J Surg Res
  
  Volume: 180 Pages: 62-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791069
[Journal Article] 巨核球造血とアポトーシス2012
- Author(s)
  上妻行則
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 23 Pages: 552-558
- NAID
  130003367325
- Data Source
  KAKENHI-PROJECT-23791069
[Journal Article] Procoagulant properties of microparticles released from red blood cells in paroxysmal nocturnal haemoglobinuria.2011
- Author(s)
  Kozuma Y, Sawahata Y, Takei Y, Chiba S, Ninomiya H.
- Journal Title
  
  Br J Haematol. vol.152
  
  Pages: 631-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] Procoagulant properties of microparticles released from red blood cells in paroxysmal nocturnal haemoglobinuria.2011
- Author(s)
  Yukinori Kozuma
- Journal Title
  
  British Journal of Haematology
  
  Volume: VOL.152 Pages: 631-639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] Ham試験ほか,PNHに関する血液検査2010
- Author(s)
  上妻行則
- Journal Title
  
  日本臨床増刊広範囲血液・尿化学検査免疫学的検査 68
  
  Pages: 629-631
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 巨核球分化におけるカスパーゼ活性化の意義2010
- Author(s)
  上妻行則、小島寛
- Journal Title
  
  血液・腫瘍科 60
  
  Pages: 192-199
- NAID
  40019064705
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] (ショ糖水)試験,Ham試験2010
- Author(s)
  上妻行則、二宮治彦,砂糖水
- Journal Title
  
  Medicina 47巻
  
  Pages: 60-62
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] Ham試験ほか,PNHに関する血液検査2010
- Author(s)
  上妻行則、二宮治彦
- Journal Title
  
  日本臨床(広範囲血液・尿化学検査免疫学的検査) 増刊号 68巻
  
  Pages: 629-631
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] The pro-apoptotic BH3-only protein Bim regulates cell cycle progression of hematopoietic progenitors during megakaryopoiesis.2010
- Author(s)
  Kozuma Y, Ninomiya H, Murata S, Kono T, Mukai HY, Kojima H.
- Journal Title
  
  J Thromb Haemost. vol.8
  
  Pages: 1088-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] Enhanced expression of CD71, transferrin receptor, on immature reticulocytes in patientswith paroxysmal nocturnal hemoglobinuria.2010
- Author(s)
  Sato S, Kozuma Y, Hasegawa Y, Kojima H, Chiba S, Ninomiya H.
- Journal Title
  
  Int J Lab Hematol. 32(1 Pt 1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 貧血の検査法b)溶血に関する検査2010
- Author(s)
  上妻行則、二宮治彦
- Journal Title
  
  血液診療エキスパート貧血
  
  Pages: 48-53
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] The pro-apoptotic BH-3-only protein Bim regulates cell cycle progression of hematopoietic progenitors during megakaryopoiesis2010
- Author(s)
  Yukinori Kozuma
- Journal Title
  
  Journal of Thrombosis and Haemostasis (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] The pro-apoptotic BH-3-only protein Bim regulates cell cycle progression of hematopoietic progenitors during megakaryopoiesis2010
- Author(s)
  Yukinori Kozuma
- Journal Title
  
  Journal of Thrombosis and Haemostasis
  
  Volume: VOL.8 Pages: 1088-1097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 砂糖水(ショ糖水)試験,Ham試験2010
- Author(s)
  上妻行則
- Journal Title
  
  Medicina
  
  Volume: VOL.47 Pages: 60-62
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 貧血の検査法b)溶血に関する検査2010
- Author(s)
  上妻行則
- Journal Title
  
  血液診療エキスパート貧血
  
  Pages: 48-53
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 巨核球分化におけるカスパーゼ活性化の意義2010
- Author(s)
  上妻行則
- Journal Title
  
  血液・腫瘍科 60(2)
  
  Pages: 192-199
- NAID
  40019064705
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 発作性夜間ヘモグロビン尿症(PNH)診断のためのCD55,CD59検査2009
- Author(s)
  上妻行則
- Journal Title
  
  診断と治療 97(9)
  
  Pages: 1924-1926
- Data Source
  KAKENHI-PROJECT-21890024
[Journal Article] 発作性夜間血色素尿症(PNH)診断のためのCD55,CD59検査2009
- Author(s)
  上妻行則、二宮治彦
- Journal Title
  
  診断と治療 97巻
  
  Pages: 1924-1926
- Data Source
  KAKENHI-PROJECT-21890024
[Patent] 重炭酸イオンまたは重炭酸塩を含有する血小板機能の維持及び/又は増強剤2016
- Inventor(s)
  上妻行則、山本哲哉
- Industrial Property Rights Holder
  株式会社大塚製薬工場　国立大学法人筑波大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-078983
- Filing Date
  2016-03-10
- Data Source
  KAKENHI-PROJECT-26860718
[Presentation] Significance of measuring microparticles derived from stored platelets.2021
- Author(s)
  Noboruo I, Nambu M, Kawaguchi T, Kozuma Y.
- Organizer
  The 6th Allied Health Sciences International Symposium 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] Daratumumab の輸血検査干渉の回避を目指した基礎研究2020
- Author(s)
  登尾一平、山本隆敏、田邊香野、池田勝義、川口辰哉、上妻行則.
- Organizer
  第68回日本輸血・細胞治療学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] Microparticles released from stored platelet increase coagulation ability.2020
- Author(s)
  Noboruo I, Yamamoto T, Tanabe K, Kawaguchi T, Ikeda K, Kozuma Y.
- Organizer
  The XXVIII Congress of the International Society on Thrombosis and Haemostasis.
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 保管血小板における MP の経時的変化とその役割2020
- Author(s)
  登尾一平、山本隆敏、田邊香野、川口辰哉、上妻行則.
- Organizer
  第42回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 保存血小板における老化マーカーの有用性の検討2019
- Author(s)
  登尾一平、山本隆敏、田邊香野、川口辰哉、上妻行則
- Organizer
  日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 医療系大学における遺伝子技術教育教材の開発と飲酒に関する生活指導への応用の可能性2019
- Author(s)
  田邊香野、楢原真二、上妻行則、山本隆敏、川口辰哉
- Organizer
  日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 交差混合試験の新規実習教材の開発－直接経口抗凝固薬、ribaroxaban を用いたインヒビター疑似検体の有用性の検討ー2019
- Author(s)
  渡邊一史、平野京介、佛淵悠大、登尾一平、山本隆敏、上妻行則
- Organizer
  日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 保存血小板における老化マーカーの変化2019
- Author(s)
  登尾一平、山本隆敏、田邊香野、川口辰哉、上妻行則
- Organizer
  日本輸血細胞治療学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] MMP is involved in platelet senescence on platelet concentrates.2019
- Author(s)
  I, Noboruo, T. Yamamoto, K. Tanabe, T. Kawaguchi, Y. Kozuma
- Organizer
  Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] Artificial cerebrospinal fluid can recover platelet function inhibited by aspirin.2019
- Author(s)
  Y. Kozuma, I. Noboruo, T. Kawaguchi, H. Ninomiya, T. Yamamoto
- Organizer
  Congress of International Society on Thrombosis and Haemostasis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 保存血小板における老化マーカーの変化2019
- Author(s)
  登尾一平、山本隆敏、田邊香野、川口辰哉、上妻行則
- Organizer
  日本臨床検査学教育学会学術大会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 神経内視鏡手術で用いられる人工髄液による aspirin 添加血小板の活性化増強効果2018
- Author(s)
  上妻行則、井上智佐子、山本哲哉、二宮治彦
- Organizer
  第40回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08587
[Presentation] 巨核球造血における抗血小板抗体の影響-免疫性血小板減少症モデルマウスを用いた検討-2017
- Author(s)
  上妻行則、小島寛、沼知奈保子、二宮治彦
- Organizer
  第39回日本血栓止血学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2017-06-08
- Data Source
  KAKENHI-PROJECT-26860718
[Presentation] 神経内視鏡手術で用いられる人工髄液による止血メカニズム-Sodium bicarbonate の有用性を探る-2016
- Author(s)
  上妻行則、山本哲哉、阿久津博義、石川栄一、松田真秀、吉田文代、高野晋吾、松村明、二宮治彦
- Organizer
  第38回日本血栓止血学会学術集会
- Place of Presentation
  奈良春日野国際フォーラム(奈良県奈良市）
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-26860718
[Presentation] Anti-GPIIb antibody inhibits platelet production from megakaryocytes, but not megakaryocyte maturation, analyzed in a murine model of immune thrombocytopenia.2015
- Author(s)
  Yukinori Kozuma, Hiroshi Kojima, Haruhiko Ninomiya.
- Organizer
  XXV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Toronto, Canada
- Year and Date
  2015-06-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860718
[Presentation] 顕微鏡下脳神経外科手術で用いられる人工髄液は血小板活性化を増幅させ、止血促進に寄与する2015
- Author(s)
  上妻行則、山本哲哉、石川栄一、吉田文代、阿久津博義、松田真秀、中井啓、鶴田和太郎、高野晋吾、松村明、二宮治彦
- Organizer
  第37回日本血栓止血学会
- Place of Presentation
  甲府市総合市民会館（山梨）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26860718
[Presentation] 人工髄液灌流による止血メカニズム- Sodium bicarbonate による血小板凝集の増強-2015
- Author(s)
  上妻行則、山本哲哉、阿久津博義、石川栄一、松田真秀、吉田文代、高野晋吾、松村明、二宮治彦
- Organizer
  第22回日本神経内視鏡学会
- Place of Presentation
  ホテル松島大観荘（宮城）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26860718
[Presentation] 血小板におけるcaspase-3活性化の意義の検討2013
- Author(s)
  上妻行則,関崎沙織,田代ゆう子,小島寛,二宮治彦
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] Caspase-3 activation regulates platelet lifespan but it is not involved in microparticle (MP) formation and phosphatidylserine (PS) exposure.2013
- Author(s)
  Yukinori Kozuma, Hiroshi Kojima, Yuko Tashiro, Haruhiko Ninomiya
- Organizer
  XXIV Congress of The International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam RAI(Amsterdam、Netherlands)
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] 血小板におけるcaspase-3活性化の意義の検討2013
- Author(s)
  上妻行則、関崎沙織、田代ゆう子、小島寛、二宮治彦
- Organizer
  第35回日本血栓止血学会学術集会
- Place of Presentation
  山形国際ホテル(山形市）
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] Caspase-3 activation regulates platelet lifespan but it is not involved in microparticle (MP) formation and phosphatidylserine (PS) exposure2013
- Author(s)
  Kozuma Y, Kojima H, Tashiro Y, Ninomiya H
- Organizer
  XXIV Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Amsterdam (Nethrlands)
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation]2012
- Author(s)
  高橋一広,村田聡一郎,上妻行則,鈴木英紀,野渡剛之,丸山岳人,田村孝史,野崎礼次,池田直哉,川崎卓也,大河内信弘
- Organizer
  第112回日本外科学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] Human platelets promote liver regeneration with Kupffer cells in SCID mice2012
- Author(s)
  Takahashi K, Kozuma Y, Suzuki H, Ohkihchi N
- Organizer
  The 7^<th> Tsukuba Medical Science Research Meeting
- Place of Presentation
  Tsukuba (Japan)
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation]2012
- Author(s)
  高橋一広,上妻行則,鈴木英紀,野渡剛之,丸山岳人,田村孝史,野崎礼次,村田聡一郎,大河内信弘
- Organizer
  第48回日本肝臓学会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] Platalet activation is negatively regulated by the molecular interaction of platelet surface CD226 with CD112 expressed on endothelial cells2011
- Author(s)
  Kozuma Y, Ninomiya H, Shibuya K, Shibuya A, Kojima H
- Organizer
  XXIII Congress of the International Society on Thrombosis and Haemostasis
- Place of Presentation
  Kyoto (Japan)
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] Platelet activation in negatively regulated by the molecular interaction of platelet surface CD226 with CD112 expressed on endothelial cells.2011
- Author(s)
  上妻行則、二宮治彦、渋谷和子、渋谷彰、小島寛
- Organizer
  第23回国際血栓止血学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-23791069
[Presentation] 巨核球造血における細胞間接着因子CD226(DNAM-1)の役割2010
- Author(s)
  上妻行則
- Organizer
  第33回日本血栓止血学会学術集会
- Place of Presentation
  城山観光ホテル(鹿児島県)
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21890024
[Presentation] 巨核球造血における細胞間接着因子CD226(DNAM-1)の役割2010
- Author(s)
  上妻行則
- Organizer
  日本血栓止血学会学術集会
- Place of Presentation
  城山観光ホテル(鹿児島県)
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21890024
[Presentation] 巨核球造血におけるapoptosis関連タンパクの役割2009
- Author(s)
  上妻行則
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890024
[Presentation] 巨核球造血・血1小板産生に対する抗血1小板抗体の影響2009
- Author(s)
  上妻行則
- Organizer
  第32回日本血栓止血学会学術集会
- Place of Presentation
  リーガロイヤルホテル小倉・北九州国際会議場(福岡県)
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-21890024
[Presentation] 巨核球造血におけるapoptosis関連タンパクの役割2009
- Author(s)
  上妻行則
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21890024
[Presentation] 血小板活性化制御における calpastatin の役割
- Author(s)
  生田理紗、上妻行則、田代ゆう子、佐川このみ、高野二郎、西道隆臣、小島寛、二宮治彦
- Organizer
  第 36 回日本血栓止血学会
- Place of Presentation
  大阪国際交流センター
- Year and Date
  2014-05-29 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-26860718

1. 二宮治彦 (10198533)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 登尾一平 (00832007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. Hirotoshi Miyoshi (70292547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山本隆敏 (10746233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. 田邊香野 (20761282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 上野志貴子 (40571047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 川口辰哉 (50244116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高橋一広 (80794528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 内場光浩 (90315292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 平松祐司 (30302417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 鈴木保之 (60344595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kozuma Yukinori 上妻 行則

KOZUMA Yukinori 上妻 行則

Research Projects

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Co-Researchers

体外循環時に生じる人工肺内圧の上昇および術後出血を防止するための革新的戦略Principal Investigator

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抗補体療法下の PNH 血小板異常と血栓メカニズムの解析

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老化血小板を用いた肝疾患における新規治療法確立を目指した基礎研究

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体外式膜型人工肺（ECMO）における血栓形成ゼロを目指した新たな制御戦略Principal Investigator

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Development of the new hemostatic which is available by emergency surgery and the platelet agentPrincipal Investigator

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Ex vivo reconstruction of hematopoietic functions using three-dimensional freeze-thawed feeder cell layer

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Systematic analysis of megakaryopoiesis and platelet functionPrincipal Investigator

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Analysis of the molecular mechanism regulated during megakaryopoiesis and platelet functionPrincipal Investigator

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Systematic analysis of megakaryopoiesis and platelet production by using genetically modified mice.Principal Investigator

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[Book] 若葉マーク臨床検査技師エッセンス・ノート2臨床形態検査、止血・凝固・線溶機構2013

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[Journal Article] 医療系大学の双方向型授業におけるインフルエンザ感染拡大のリスクと対策2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation.2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 学内における交差混合試験理解のための Rivaroxaban の応用2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 巨核球造血におけるアポトーシス関連タンパクの役割2020

Kozuma Yukinori 上妻行則

KOZUMA Yukinori 上妻行則