Kamon Masayoshi 加門正義

Researcher Number	90557224
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所疾病研究第五部, リサーチフェロー
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所疾病研究第五部, リサーチフェロー 2020 – 2022: 愛媛大学, 医学系研究科, 助教 2019: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所疾病研究第五部, 科研費研究員 2017 – 2018: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所疾病研究第五部, 流動研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords	Principal Investigator iPS細胞 / リピート病 / DM1 / 筋分化 / エピゲノム / DNAメチル化 / DNAミスマッチ修復 / 疾患iPS細胞 / スクリーニング / 筋強直性ジストロフィー / スプライシング異常 / Splicing

新規エピゲノム編集技術を用いたiPS細胞の筋分化におけるDNAメチル化機能の解明Principal Investigator
- Principal Investigator
  
  加門正義
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  National Center of Neurology and Psychiatry
The repeat expansion mechanism in Myotonic dystrophy type 1 patient-derived iPSCs.Principal Investigator
- Principal Investigator
  
  Masayoshi Kamon
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Ehime University
  National Center of Neurology and Psychiatry
Myotonic dystrophy type 1 patient-derived iPS cells and splicing reporter for drug screeningPrincipal Investigator
- Principal Investigator
  
  Kamon Masayoshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  National Center of Neurology and Psychiatry

All 2022 2021 2020 2018 2017

All Journal Article Presentation Book

[Book] Myotonic Dystrophy: Disease Modeling and Drug Development with DM12018
- Author(s)
  Toshiyuki Araki, Masayoshi Kamon, and Hidetoshi Sakurai
- Total Pages
  214
- Publisher
  Springer
- ISBN
  9789811305078
- Data Source
  KAKENHI-PROJECT-17K16711
[Journal Article] A mutation in DOK7 in congenital myasthenic syndrome forms aggresome in cultured cells, and reduces DOK7 expression and MuSK phosphorylation in patient-derived iPS cells2022
- Author(s)
  Zhang Shaochuan、Ohkawara Bisei、Ito Mikako、Huang Zhizhou、Zhao Fei、Nakata Tomohiko、Takeuchi Tomoya、Sakurai Hidetoshi、Komaki Hirofumi、Kamon Masayoshi、Araki Toshiyuki、Ohno Kinji
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 32 Issue: 9 Pages: 1511-1523
- DOI
  10.1093/hmg/ddac306
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06392, KAKENHI-PROJECT-21H04815, KAKENHI-PROJECT-20H03561, KAKENHI-PROJECT-19K09565, KAKENHI-PROJECT-23K06412, KAKENHI-PROJECT-20K06925, KAKENHI-PROJECT-23K27485
[Journal Article] Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells.2020
- Author(s)
  Huang K, Masuda A, Chen G, Bushra S, Kamon M, Araki T, Kinoshita M, Ohkawara B, Ito M, Ohno K
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 2558-2558
- DOI
  10.1038/s41598-020-59517-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06058, KAKENHI-PROJECT-19K09565, KAKENHI-PROJECT-19K22802, KAKENHI-PROJECT-17K07094
[Journal Article] Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability.2017
- Author(s)
  Ueki J, Nakamori M, Nakamura M, Nishikawa M, Yoshida Y, Tanaka A, Morizane A, Kamon M, Araki T, Takahashi MP, Watanabe A, Inagaki N, Sakurai H.
- Journal Title
  
  Sci Rep.
  
  Volume: 13 Issue: 1 Pages: 42522-42522
- DOI
  10.1038/srep42522
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05326, KAKENHI-PROJECT-15J04853, KAKENHI-PROJECT-25713034, KAKENHI-PROJECT-26430053, KAKENHI-PROJECT-15K15339, KAKENHI-PROJECT-15K21113, KAKENHI-PROJECT-17K16711, KAKENHI-PROJECT-16H05321
[Presentation] AMNION FORMATION IS THE FIRST EMT PROGRAM IN HUMAN DEVELOPMEN2021
- Author(s)
  Masayoshi Kamon, Hidemasa Kato
- Organizer
  ISSCR TOKYO Symposium, 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09565
[Presentation] 不死化ヒト結膜上皮細胞株(iHCjEC)を用いた杯細胞分化誘導条件の検討2021
- Author(s)
  竹澤由起、加門正義、加門啓子、加藤英政、白石敦
- Organizer
  2021年度分子生物学会
- Data Source
  KAKENHI-PROJECT-19K09565
[Presentation] QUANTITATIVE DNA METHYLATION ANALYSIS OF BIVALENT DOMAINS ALLOWS SELECTING TUMOR-PRONE HUMAN IPS CELL CLONES2021
- Author(s)
  Keiko Hiraki-Kamon, Makoto Motono, Masayoshi Kamon, Hideki Masaki, Ayaka Saito, Hidenori Kiyosawa, Yoichi Kondo and Hidemasa Kato
- Organizer
  ISSCR, 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09565
[Presentation] WNTシグナルが引き起こすヒト羊膜上皮細胞分化過程における上皮間葉転換2021
- Author(s)
  加門正義、加藤英政
- Organizer
  2021年度分子生物学会
- Data Source
  KAKENHI-PROJECT-19K09565
[Presentation] ヒトiPS細胞由来の細胞を用いた神経筋接合部モデルの構築2020
- Author(s)
  加門正義、若月修二、蕭淑麗(SIEW SOKELEE)、荒木敏之
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K09565
[Presentation] DM1疾患特異的iPS細胞におけるCTGリピート伸長メカニズムの解明2018
- Author(s)
  加門正義、若月修二、荒木敏之
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-17K16711
[Presentation] DM1疾患特異的iPS細胞におけるCTGリピート伸長メカニズムの解明2018
- Author(s)
  加門正義、若月修二、荒木敏之
- Organizer
  再生医療学会
- Data Source
  KAKENHI-PROJECT-17K16711
[Presentation] DM1疾患特異的iPS細胞におけるCTGリピート伸長メカニズムの解明2017
- Author(s)
  加門正義、若月修二、荒木敏之
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-17K16711

1. 大河原美静

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 稲垣暢也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 増田章男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kamon Masayoshi 加門 正義

Research Projects

Research Products

Co-Researchers

新規エピゲノム編集技術を用いたiPS細胞の筋分化におけるDNAメチル化機能の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The repeat expansion mechanism in Myotonic dystrophy type 1 patient-derived iPSCs.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Myotonic dystrophy type 1 patient-derived iPS cells and splicing reporter for drug screeningPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Myotonic Dystrophy: Disease Modeling and Drug Development with DM12018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] A mutation in DOK7 in congenital myasthenic syndrome forms aggresome in cultured cells, and reduces DOK7 expression and MuSK phosphorylation in patient-derived iPS cells2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of cyclooxygenase-1 by nonsteroidal anti-inflammatory drugs demethylates MeR2 enhancer and promotes Mbnl1 transcription in myogenic cells.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myotonic dystrophy type 1 patient-derived iPSCs for the investigation of CTG repeat instability.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] AMNION FORMATION IS THE FIRST EMT PROGRAM IN HUMAN DEVELOPMEN2021

Author(s)

Organizer

Data Source

[Presentation] 不死化ヒト結膜上皮細胞株(iHCjEC)を用いた杯細胞分化誘導条件の検討2021

Author(s)

Organizer

Data Source

[Presentation] QUANTITATIVE DNA METHYLATION ANALYSIS OF BIVALENT DOMAINS ALLOWS SELECTING TUMOR-PRONE HUMAN IPS CELL CLONES2021

Author(s)

Organizer

Data Source

[Presentation] WNTシグナルが引き起こすヒト羊膜上皮細胞分化過程における上皮間葉転換2021

Author(s)

Organizer

Data Source

[Presentation] ヒトiPS細胞由来の細胞を用いた神経筋接合部モデルの構築2020

Author(s)

Organizer

Data Source

[Presentation] DM1疾患特異的iPS細胞におけるCTGリピート伸長メカニズムの解明2018

Author(s)

Organizer

Data Source

[Presentation] DM1疾患特異的iPS細胞におけるCTGリピート伸長メカニズムの解明2018

Author(s)

Organizer

Data Source

[Presentation] DM1疾患特異的iPS細胞におけるCTGリピート伸長メカニズムの解明2017

Author(s)

Organizer

Data Source

Kamon Masayoshi 加門正義