Anazawa Takayuki 穴澤貴行

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ANAZAWA Takayuki 穴澤貴行

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Researcher Number	90566811
Other IDs
Affiliation (Current)	2023: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2016 – 2022: 京都大学, 医学研究科, 助教 2015: 京都大学, 医学(系)研究科(研究院), 助教 2010 – 2014: 福島県立医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator Digestive surgery / General surgery
Keywords	Principal Investigator 膵島移植 / 糖尿病 / 細胞移植 / 移植・再生医療 / 外科学 / 再生医療 / 免疫寛容 / 皮下移植 / 膵島分離 / イオンチャネル … More / 細胞・組織 / 外科 / 小胞体ストレス / 移植外科学 / 免疫抑制 / 免疫抑制剤 … More Except Principal Investigator calreticulin / 細胞死 / 膵島 / 亜致死刺激 / 免疫寛容 / 細胞周期停止 / Mitomycin C / HMGB1 / 移植 / 酸化ストレス / 小胞体ストレス / 膵島移植 / High-mobility group box 1 / binding immunoglobulin protein / DAMPｓ / HMGB-1 / マイトマイシンC / Supported Molecular Matrix Electrophoresis(SMME)法 / ムチン / polyethylene glycol / polyvinyl alcohol / O-結合型糖鎖 / 免疫療法 / 担癌状態 / MDSC / 膵癌 / 骨髄由来抑制細胞 / 腫瘍免疫 / 徐放物質 / フィブリン / OK-432 Less

Development of Immune Tolerance Space Construction Method for Cell Transplantation Based on Elucidation of Mechanism of Subcutaneous Vascular Induction ResponsePrincipal Investigator
- Principal Investigator
  
  穴澤貴行
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
Development of novel immunosuppressive method using MEK inhibitor to construct optimal environment for pancreatic islet transplantationPrincipal Investigator
- Principal Investigator
  
  Anazawa Takayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyoto University
Bioinformatics approach to establish preconditioning method for beta cell replacementPrincipal Investigator
- Principal Investigator
  
  Anazawa Takayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Induction of anti-tumor immune response using a Tissue Engineering technique
- Principal Investigator
  
  GOTOH Mitsukazu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University
Protection of pancreatic islets by controlling both the volume-sensitive chloride channel and endoplasmic reticulum stress responsePrincipal Investigator
- Principal Investigator
  
  ANAZAWA Takayuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University
Immunological effect of myeloid-derived suppressor cells in pancreatic cancer patients and its alteration after treatment
- Principal Investigator
  
  KENJO Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University
Optimization of collagenase activity and regulation of ion channel associated with cell viability for improving pancreatic islet transplantationPrincipal Investigator
- Principal Investigator
  
  ANAZAWA Takayuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University
Immunological tolerance induced by surviving but not dying cellsfollowing sublethal stress
- Principal Investigator
  
  GOTOH Mitsukazu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University
Long-term islet graft survival induced by regulating HMGB-1
- Principal Investigator
  
  SAITO Takaharu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University
新規糖鎖解析システム(SMME法)を用いた癌特異的糖鎖抗原の探索
- Principal Investigator
  
  後藤満一
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Fukushima Medical University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

[Journal Article] The MEK Inhibitor Trametinib Suppresses Major Histocompatibility Antigen-mismatched Rejection Following Pancreatic Islet Transplantation2020
- Author(s)
  Seiichiro Tada, Takayuki Anazawa et al.
- Journal Title
  
  Transplantation Direct
  
  Volume: 6
- DOI
  10.1097/txd.0000000000001045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08593, KAKENHI-PROJECT-19K08812
[Journal Article] Current state and future evolution of pancreatic islet transplantation2018
- Author(s)
  Anazawa Takayuki、Okajima Hideaki、Masui Toshihiko、Uemoto Shinji
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 3 Pages: 34-42
- DOI
  10.1002/ags3.12214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08593, KAKENHI-PROJECT-18K08677
[Journal Article] β Cell Replacement Therapy: The Next 10 Years2018
- Author(s)
  Schuetz Christian、Anazawa Takayuki、Cross Sarah E.、Labriola Leticia、Meier Raphael P.H.、Redfield Robert R.、Scholz Hanne、Stock Peter G.、Zammit Nathan W.
- Journal Title
  
  Transplantation
  
  Volume: 102 Pages: 215-229
- DOI
  10.1097/tp.0000000000001937
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10033
[Journal Article] Ex vivo pretreatment of islets with mitomycin C: Reduction in immunogenic potential of islets by suppressing secretion of multiple chemotactic factors2017
- Author(s)
  Sato N, Anazawa T et al.
- Journal Title
  
  Cell Transplantation
  
  Volume: In press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10033
[Journal Article] Ex vivo Pretreatment of Islets with Mitomycin C: Reduction in Immunogenic Potential of Islets by Suppressing Secretion of Multiple Chemotactic Factors2017
- Author(s)
  Sato Naoya、Haga Junichiro、Anazawa Takayuki、Kenjo Akira、Kimura Takashi、Wada Ikuo、Mori Tsutomu、Marubashi Shigeru、Gotoh Mitsukazu
- Journal Title
  
  Cell Transplantation
  
  Volume: 26 Pages: 1392-1404
- DOI
  10.1177/0963689717721233
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16512, KAKENHI-PROJECT-15K10033, KAKENHI-PROJECT-17K19687
[Journal Article] Severely fibrotic pancreases from young patients with chronic pancreatitis: evidence for a ductal origin of islet neogenesis2013
- Author(s)
  （Soltani SM）、Anazawa T
- Journal Title
  
  Acta Diabetol
  
  Volume: 50 Pages: 807-814
- DOI
  10.1007/s00592-011-0306-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861208
[Journal Article] Serum levels of vascular endothelial growth factor are increased and correlate with malnutrition, immunosuppression involving MDSCs and systemic inflammation in patients with cancer of the digestive system.2013
- Author(s)
  Nakamura I, Shibata M, Gonda K, Yazawa T, Shimura T, Anazawa T, Suzuki S, Sakurai K, Koyama Y, Ohto H, Tomita R, Gotoh M, Takenoshita S.
- Journal Title
  
  Oncology Letters
  
  Volume: 5 Pages: 1682-1686
- DOI
  10.3892/ol.2013.1231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592035
[Journal Article] 膵島移植症例登録報告（2012）2013
- Author(s)
  穴澤　貴行
- Journal Title
  
  移植
  
  Volume: 48 Pages: 384-389
- Data Source
  KAKENHI-PROJECT-25861208
[Journal Article] Factors affecting transplant outcomes in diabetic nude mice receiving human, porcine, and nonhuman primate islets: analysis of 335 transplantations.2013
- Author(s)
  （Loganathan G）、Anazawa T
- Journal Title
  
  Transplantation
  
  Volume: 95 Pages: 1439-1447
- DOI
  10.1097/tp.0b013e318293b7b8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25861208
[Journal Article] Adenine nucleotide levels in a closed enzymatic digestion system for porcine islet isolation.2012
- Author(s)
  Oshibe I, Saito T, Sato Y, Saito T, Tsukada M, Ise K, Kenjo A, Kimura T, Anazawa T, Suzuki S, Hashimoto Y, Gotoh M
- Journal Title
  
  Cell Transplantation
  
  Volume: 21(2-3) Pages: 483-491
- DOI
  10.3727/096368911x605394
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591412
[Journal Article] 膵島移植症例登録報告（2011）2012
- Author(s)
  穴澤　貴行
- Journal Title
  
  移植
  
  Volume: 47 Pages: 443-449
- NAID
  10030209416
- Data Source
  KAKENHI-PROJECT-23791554
[Journal Article] A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products2012
- Author(s)
  （Balamurugan AN） Takayuki Anazawa
- Journal Title
  
  Transplantation
  
  Volume: 93 Pages: 693-702
- DOI
  10.1097/tp.0b013e318247281b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791554
[Journal Article] Mitomycin- C treatment significantly reduces central damage of islets in culture2012
- Author(s)
  Saito T, Saito T, Sato Y, Ise K, Anazawa T, Oshibe I, Haga J, Yamamoto M, Waguri S, Gotoh M.
- Journal Title
  
  Pancreas
  
  Volume: 41(2) Pages: 245-252
- DOI
  10.1097/mpa.0b013e31822461c7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591412, KAKENHI-PROJECT-22591527, KAKENHI-PROJECT-23791554
[Journal Article] A model to evaluate toxic factors influencing islets during collagenase digestion: the role of serine protease inhibitor in the protection of islets2012
- Author(s)
  Tsukada M, Saito T, Ise K, Kenjo A, Kimura T, Satoh Y, Sai to T, Anazawa T, Oshibe I, Suzuki S, Hashimoto Y, Gotoh M
- Journal Title
  
  Cell Transplantation
  
  Volume: 21(2-3) Pages: 473-482
- DOI
  10.3727/096368911x605385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591412
[Journal Article] Preservation of pancreatic islets in cold UW solution before transplantation.2012
- Author(s)
  Ishii S, Saito T, Ise K, Yamashita M, Sato Y, Saito T, Tsukada M, Oshibe I, Kenjo A, Kimura T, Anazawa T, Suzuki S, Gotoh M
- Journal Title
  
  Islets
  
  Volume: 4(1) Pages: 32-39
- DOI
  10.4161/isl.18607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591412, KAKENHI-PROJECT-23591507, KAKENHI-PROJECT-23591871
[Journal Article] Prediction of pancreatic tissue densities by an analytical test gradient system before purification maximizes human islet recovery for isletautotransplantation/allotransplantation2011
- Author(s)
  Anazawa T, Matsumoto S, Yonekawa Y, Loganathan G, Wilhelm JJ, Soltani SM, Papas KK, Sutherland DE, Hering BJ, Balamurugan AN
- Journal Title
  
  Transplantation
  
  Volume: 91(5) Pages: 508-514
- DOI
  10.1097/tp.0b013e3182066ecb
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791554
[Journal Article] Improved islet yield and function by use of a chloride channel blocker during collagenase digestion2011
- Author(s)
  Anazawa T, Sato Y, Saito T, Tsuchiya T, Kenjo A, Kimura T, Haga J, Miyake M, Waguri S, Hazama A, Gotoh M.
- Journal Title
  
  Transplantation
  
  Volume: 92(8) Pages: 871-877
- DOI
  10.1097/tp.0b013e31822e6eb4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248, KAKENHI-PROJECT-22591527, KAKENHI-PROJECT-23791554
[Journal Article] Actions of the Japanese Pancreas and Islet Transplantation Association Regarding Transplanted Human Islets Isolated Using Liberase HI2010
- Author(s)
  Saito T, Anazawa T, Gotoh M, Uemoto S, Kenmochi T, Kuroda Y, Satomi S, Itoh T, Yasunami Y, Kitamoto T, Mohri S, Teraoka S
- Journal Title
  
  Transplantation Proceedings.
  
  Volume: 42(10) Pages: 4213-4216
- DOI
  10.1016/j.transproceed.2010.09.142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390248
[Patent] 細胞分離用酵素溶液及び細胞分離方法、並びに膵島分離方法2013
- Inventor(s)
  穴澤貴行
- Industrial Property Rights Holder
  穴澤貴行、狹間章博、後藤満一
- Filing Date
  2013-01-29
- Overseas
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Islet Transplantation in Japan2021
- Author(s)
  Takayuki Anazawa
- Organizer
  The 2nd Congress of Asian Pancreas and Islet Transplant Association Pancreas and islet transplantation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] Efficacy and safety of islet transplantation in patients with type 1 diabetes:a Japanese single center experience2020
- Author(s)
  Takayuki Anazawa, et al.
- Organizer
  28th International Congress of The Transplantation Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] 膵島移植における新たな作用機序による免疫抑制療法の開発と今後の展望2019
- Author(s)
  多田誠一郎、穴澤貴行、他
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] 膵島移植におけるMEK阻害剤の可能性2019
- Author(s)
  多田誠一郎、穴澤貴行、他
- Organizer
  第55回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] 膵島移植における新たな作用機序による免疫抑制療法の開発：MEK阻害剤の応用可能性2019
- Author(s)
  多田誠一郎、穴澤貴行、他
- Organizer
  第46回日本膵膵島移植研究会
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] MEK阻害剤トラメチニブはMHC不適合マウス膵島移植で膵島毒性を示すことなく拒絶反応を抑制する2019
- Author(s)
  多田誠一郎、穴澤貴行、他
- Organizer
  第28回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] Establishment of islet allograft acceptance by mitogen-activated protein kinase kinase via suppression of alloreactive T cells2019
- Author(s)
  Seiichiro Tada, Takayuki Anazawa
- Organizer
  17th World Congress of the International Pancreas & Islet Transplant Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] 血管床の誘導が皮下膵島移植に与える免疫学的な影響因子の検討2018
- Author(s)
  多田誠一郎、穴澤貴行、他
- Organizer
  第45回日本臓器保存生物医学会
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] A simple and promising strategy for pancreatic islet preconditioning to reduce immunogenicity and improve islet graft longevity2018
- Author(s)
  Takayuki Anazawa, Kei Yamane, Seiichiro Tada, Kenta Inoguchi, Toshihiko Masui, Kazuyuki Nagai, Naoya Sato, Shoichiro Sumi, Hideaki Okajima, Shinji Uemoto
- Organizer
  27th International Congress of The Transplantation Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] レシピエントの免疫応答が血管床誘導による皮下膵島移植に与える影響2018
- Author(s)
  多田誠一郎、穴澤貴行、他
- Organizer
  第54回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] A simple and promising strategy for pancreatic islet preconditioning to reduce immunogenicity and improve islet graft longevity2018
- Author(s)
  Takayuki Anazawa, et al.
- Organizer
  27th International Congress of the transplantation society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08593
[Presentation] A comparative analysis of the clinical outcome of islet transplantation using donors after cardiac death vs intensive insulin therapy in patients with type 1 diabetes with severe hypoglycaemia unawareness: a 10-year follow-up at a single centre2017
- Author(s)
  Takayuki Anazawa, Hideaki Okajima, Yasuhiro Iwanaga, Toshihiko Masui, Seiichiro Tada, Kei Yamane,Kenta Inokuchi, Kyoichi Takaori, Yoshiya Kawaguchi, Shinji Uemoto
- Organizer
  16th International Congress of International Pancreas and Islet Transplant Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] 膵島移植の方向性：臨床経験からの成果と課題2017
- Author(s)
  穴澤貴行、岡島英明、増井俊彦、伊藤孝司、多田誠一郎、山根　佳、井ノ口健太、海道利美、上本伸二
- Organizer
  第53回日本移植学会
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] 膵島移植の現状と今後の展開：膵島移植技術は日本で活かせるのか？2017
- Author(s)
  穴澤貴行
- Organizer
  第72回日本消化器外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] 膵島移植が拓く近未来の組織・細胞治療2017
- Author(s)
  穴澤貴行
- Organizer
  第16回日本組織移植学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] 次世代の細胞移植療法開発における探索的医療研究の役割：膵島移植からの成果報告2016
- Author(s)
  穴澤貴行、他
- Organizer
  第116回日本外科学会定期学術集会（ワークショップ）
- Place of Presentation
  大阪
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] A 10-year outcome of pancreatic islet transplantation2016
- Author(s)
  Anazawa T, et al
- Organizer
  IAP and JPS and AOPA 2016
- Place of Presentation
  Sendai, Japan
- Year and Date
  2016-08-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] Comprehensive gene analysis on ex-vivo Mitomycin-C treatment as a potential protocol for inducing unresponsiveness to islet engraftment: harmonized downregulation of multiple chemotaxis factors2015
- Author(s)
  Naoya Sato, Takayuki Anazawa, et al.
- Organizer
  IPITA-IXA-CTS 2015 Joint Congress
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] Pancreatic islet culture induces tolerogenic effects as well as stimulates immune cell trafficking by regulating inflammatory cytokines2015
- Author(s)
  Takayuki Anazawa, et al.
- Organizer
  IPITA-IXA-CTS 2015 Joint Congress
- Place of Presentation
  Melbourne, Australia
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10033
[Presentation] Clinical islet transplantation in Japan2014
- Author(s)
  Takayuki Anazawa
- Organizer
  Japan Korea Transplantation Forum 2014
- Place of Presentation
  Tokyo
- Year and Date
  2014-09-12
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] 再生医学研究が変える膵島移植医療の近未来2013
- Author(s)
  穴澤　貴行
- Organizer
  日本外科学会定期学術集会
- Place of Presentation
  福岡県
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] 脳死ドナー膵島移植：期待と課題2013
- Author(s)
  穴澤　貴行
- Organizer
  日本移植学会総会
- Place of Presentation
  京都府
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] 本邦の臨床膵島移植の成績と課題2013
- Author(s)
  穴澤　貴行
- Organizer
  日本肝胆膵外科学会・学術集会
- Place of Presentation
  栃木県
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] Long-term follow-up of clinical islet transplantation using donors after cardiac death: Report of the Japan Islet Transplantation Registry2013
- Author(s)
  Takayuki Anazawa
- Organizer
  Congress of the Asian Society of Transplantation
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] "Long-term Outcomes of Clinical Islet Transplantation Using Donors After Cardiac Death: A Multicenter Experience in Japan"2013
- Author(s)
  Takayuki Anazawa
- Organizer
  World congress of International pancreas and islet transplantation association
- Place of Presentation
  Monterey, CA　USA
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] 膵島移植の現状と今後の展望2012
- Author(s)
  穴澤貴行, 土屋貴男, 見城明, 伊勢一哉, 芳賀淳一郎, 齋藤拓朗, 後藤満一
- Organizer
  第48回日本移植学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Disappeared islet graft after intraportal transplantation in the recipient suffered from recurrent sepsis2012
- Author(s)
  Takayuki Anazawa
- Organizer
  24th International Congress of The Transplantation Society
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Disappeared islet graft after intraportal transplantation in the recipient suffered from recurrent sepsis2012
- Author(s)
  Anazawa T, Tsuchiya T, Kenjo A, Haga J, Sato T, Sato N, Ise K, Saito T,Tasaki K, Gotoh M
- Organizer
  24th International Congress of the Transplantation Society
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] 先進的組織細胞移植医療発展の先駆的モデルとしての膵島移植臨床開発:その展望と課題2012
- Author(s)
  穴澤貴行, 土屋貴男, 見城明, 伊勢一哉, 齋藤拓朗, 後藤満一
- Organizer
  第11回日本組織移植学会学術集会
- Place of Presentation
  東京
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Inhibition of chloride ion influx into islet cells protects islets during pancreatic islet isolation2011
- Author(s)
  Anazawa T, Tsuchiya T, Kenjo A, Haga J, Sato T, Sato N, Saito T, Sato Y, Miyake M, Hazama A, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-22390248
[Presentation] Mitomycin-C treatment protects islets from the progression of central damage during culture2011
- Author(s)
  Haga J, Saito T, Anazawa T, Tsuchiya T, Kenjo A, Sato S, Sato N, Saito T, Ise K, Yamamoto M, Waguri S, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] Cl-チャネル阻害による細胞保護効果の膵島分離への応用-臨床膵島移植確立への細胞生理学的アプローチ-2011
- Author(s)
  穴澤貴行, 土屋貴男, 見城明, 芳賀淳一郎, 佐藤哲, 三宅将生, 狹間章博, 後藤満一
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] Inhibition of chloride ion influx into islet cells protects islets during pancreatic islet isolation2011
- Author(s)
  Anazawa T, Tsuchiya T, Kenjo A, Haga J, Sato T, Sato N, Saito T, Sato Y, Miyake M, Hazama A, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Cl^-チャネル阻害による細胞保護効果の膵島分離への応用-臨床膵島移植確立への細胞生理学的アプローチ-2011
- Author(s)
  穴澤貴行, 土屋貴男, 見城明, 芳賀淳一郎, 佐藤哲, 三宅将生, 狭間章博, 後藤満一
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京(誌上開催)
- Data Source
  KAKENHI-PROJECT-22390248
[Presentation] 重症低血糖発作を伴うインスリン依存性糖尿病に対する心停止ドナーからの膵島移植:日本膵・膵島移植研究会事務局報告2011
- Author(s)
  穴澤貴行,土屋貴男,見城明,芳賀淳一郎,佐藤哲,三宅将生,狹間章博,後藤満一
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22390248
[Presentation] Mitomycin-C treatment protects islets from the progression of central damage during culture.2011
- Author(s)
  Haga J, Saito T, Anazawa T, Tsuchiya T, Kenjo A, Sato S, Sato N, Saito T, Ise K, Yamamoto M, Waguri S, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Mitomycin-C treatment protects islets from the progression of central damage during culture2011
- Author(s)
  Haga J, Saito T, Anazawa T, Tsuchiya T, Kenjo A, Sato S, Sato N, Saito T, Ise K, Yamamoto M, Waguri S, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-22390248
[Presentation] Inhibition of chloride ion influx into islet cells protects islets during pancreatic islet isolation2011
- Author(s)
  Takayuki Anazawa
- Organizer
  13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  チェコ・プラハ
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Cl-チャネル阻害による細胞保護効果の膵島分離への応用-臨床膵島移植確立への細胞生理学的アプローチ-2011
- Author(s)
  穴澤貴行, 土屋貴男, 見城明, 芳賀淳一郎, 佐藤哲, 三宅将生, 狹間章博, 後藤満一
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] Inhibition of chloride ion influx into islet cells protects islets during pancreatic islet isolation2011
- Author(s)
  Anazawa T, Tsuchiya T, Kenjo A, Haga J, Sato T, Sato N, Saito T, Sato Y, Miyake M, Hazama A, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] Inhibition of chloride ion influx into islet cells protects islets during pancreatic islet isolation.2011
- Author(s)
  Anazawa T, Tsuchiya T, Kenjo A, Haga J, Sato T, Sato N, Saito T, Sat o Y, Miyake M, Hazama A, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic.
- Data Source
  KAKENHI-PROJECT-22390248
[Presentation] Predicting porcine islet yield by acute C-peptide response to arginine stimulation of donor pigs and pancreas dithizone scoring system.2011
- Author(s)
  Anazawa T, Graham M, Abouaish J, Loganathan G, Hering BJ, A.N. Balamurugan
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic.
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] 重症低血糖発作を伴うインスリン依存性糖尿病に対する心停止ドナーからの膵島移植:日本膵・膵島移植研究会事務局報告2011
- Author(s)
  穴澤貴行, 土屋貴男, 伊勢一哉, 見城明, 齋藤拓朗, 後藤満一
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] 重症低血糖発作を伴うインスリン依存性糖尿病に対する心停止ドナーからの膵島移植:日本膵・膵島移植研究会事務局報告2011
- Author(s)
  穴澤貴行, 土屋貴男, 伊勢一哉, 見城明, 齊藤拓朗, 後藤満一
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] Cl-チャネル阻害による細胞保護効果の膵島分離への応用-臨床膵島移植確立への細胞生理学的アプローチ-2011
- Author(s)
  穴澤貴行, 土屋貴男, 見城明, 芳賀淳一郎, 佐藤哲, 三宅将生, 狹間章博, 後藤満一
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  東京(誌上開催)
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] 重症低血糖発作を伴うインスリン依存性糖尿病に対する心停止ドナーからの膵島移植:日本膵・膵島移植研究会事務局報告.2011
- Author(s)
  穴澤貴行, 土屋貴男, 伊勢一哉, 見城明, 齋藤拓朗, 後藤満一
- Organizer
  第47回日本移植学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] Mitomycin-C treatment protects islets from the progression of central damage during culture2011
- Author(s)
  Haga J, Saito T, Anazawa T, Tsuchiya T, Kenjo A, Sato S, Sato N, Saito T, Ise K, Yamamoto M, Waguri S, Gotoh M
- Organizer
  The 13th World congress of International pancreas and islet transplantation association
- Place of Presentation
  Prague, Czech Republic.
- Data Source
  KAKENHI-PROJECT-22591527
[Presentation] 先進的組織細胞移植医療発展の先駆的モデルとしての膵島移植臨床開発：その展望と課題
- Author(s)
  穴澤　貴行
- Organizer
  第11回日本組織移植学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791554
[Presentation] β細胞置換療法発展へのバイオインフォマティクス的アプローチ
- Author(s)
  穴澤　貴行
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-04-16 – 2015-04-18
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] 術前Transarterial Immunoembolization(TIE: 経動脈免疫塞栓療法)による肝細胞癌切除後再発抑制効果に対する基礎研究
- Author(s)
  佐藤　哲、見城　明、土屋貴男、斎藤拓朗、佐藤直哉、芳賀淳一郎、穴澤貴行、木村　隆、後藤満一
- Organizer
  第114回日本外科学会定期学術集会
- Place of Presentation
  国立京都国際会館・グランドプリンスホテル京都（京都府京都市）
- Year and Date
  2014-04-03 – 2014-04-05
- Data Source
  KAKENHI-PROJECT-25670558
[Presentation] Comprehensive analysis of pancreatic islet gene expression suggests inflammatory response and immune cell trafficking following islet isolation and culture
- Author(s)
  Junichiro Haga, Takayuki Anazawa
- Organizer
  World Transplant Congress
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-07-26 – 2014-07-31
- Data Source
  KAKENHI-PROJECT-25861208
[Presentation] 膵島移植の臨床展開における問題点と展望
- Author(s)
  穴澤　貴行
- Organizer
  第41回日本臓器保存生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25861208

1. GOTOH Mitsukazu (50162160)

# of Collaborated Projects: 5 results

# of Collaborated Products: 20 results
2. KENJO Akira (40305355)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
3. SAITO Takuro (20305361)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
4. TSUCHIYA Takao (70343390)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
5. ISE Kazuya (90363746)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. KIMURA Takashi (00381369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. SUZUKI Hiroyuki (30322340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. SAITO Takaharu (60508795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. SATO Yoshihiro (60347218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. 藤本七恵 (00838691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAITO Takahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
12. YAMASHITA Michitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. ISHII Shou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. MASUI Toshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 高折晃史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 進藤岳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 佐藤直哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 森努

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 上本伸二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Anazawa Takayuki 穴澤 貴行

ANAZAWA Takayuki 穴澤 貴行

Research Projects

Research Products

Co-Researchers

Development of Immune Tolerance Space Construction Method for Cell Transplantation Based on Elucidation of Mechanism of Subcutaneous Vascular Induction ResponsePrincipal Investigator

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Development of novel immunosuppressive method using MEK inhibitor to construct optimal environment for pancreatic islet transplantationPrincipal Investigator

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Bioinformatics approach to establish preconditioning method for beta cell replacementPrincipal Investigator

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Induction of anti-tumor immune response using a Tissue Engineering technique

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Protection of pancreatic islets by controlling both the volume-sensitive chloride channel and endoplasmic reticulum stress responsePrincipal Investigator

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Immunological effect of myeloid-derived suppressor cells in pancreatic cancer patients and its alteration after treatment

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Optimization of collagenase activity and regulation of ion channel associated with cell viability for improving pancreatic islet transplantationPrincipal Investigator

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Immunological tolerance induced by surviving but not dying cellsfollowing sublethal stress

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Long-term islet graft survival induced by regulating HMGB-1

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新規糖鎖解析システム(SMME法)を用いた癌特異的糖鎖抗原の探索

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[Journal Article] The MEK Inhibitor Trametinib Suppresses Major Histocompatibility Antigen-mismatched Rejection Following Pancreatic Islet Transplantation2020

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[Journal Article] Current state and future evolution of pancreatic islet transplantation2018

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[Journal Article] β Cell Replacement Therapy: The Next 10 Years2018

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Anazawa Takayuki 穴澤貴行

ANAZAWA Takayuki 穴澤貴行