YOSHIMOTO RYO 善本亮

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YOSHIMOTO Ryo 善本亮

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Researcher Number	90568817
Other IDs
Affiliation (Current)	2025: 麻布大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 麻布大学, 獣医学部, 教授 2010 – 2011: 独立行政法人国立循環器病研究センター, 血管生理学部, 室長
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / General pharmacology
Keywords	Principal Investigator ミルク / 乳児栄養 / DOHaD / 中鎖脂肪酸 / SHR / NASH / 酸化LDL / 非アルコール性脂肪肝炎(NASH) / LOX-1

母乳の中鎖脂肪酸は乳児や成長後のエネルギー代謝にどのような影響を与えるか？Principal Investigator
- Principal Investigator
  
  善本亮
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Azabu University
Role of LOX-1 in the development of non-alcoholic steat ohepatitis(NASH)Principal Investigator
- Principal Investigator
  
  YOSHIMOTO Ryo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  National Cardiovascular Center Research Institute

All 2011 2010

All Journal Article Presentation

[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox2011
- Author(s)
  Nishizuka T., Fujita Y, Sato Y, Nakano A, Kakino A, Ohshima S, Kanda T, Yoshimoto R, Sawamura T
- Journal Title
  
  Proceedings of the Japan Academy, Series B Physical and Biological Sciences
  
  Volume: 87 Pages: 104-113
- NAID
  130000669114
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] An alternative protein standard to measure activity of LOX-1 ligand containing apoB(LAB)-utilization of anti-LOX-1 single-chain antibody fused to aopB fragment2011
- Author(s)
  Iwamoto S, Fujita Y, Kakino A, Yanagida K, Matsuda H, Yoshimoto R, Sawamura T
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 18 Pages: 818-828
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox2011
- Author(s)
  Nishizuka T., Fujita Y, Sato Y, Nakano A, Kakino A, Ohshima S, Kanda T, Yoshimoto R, Sawamura T
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci
  
  Volume: 87 Pages: 104-113
- NAID
  130000669114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox.2011
- Author(s)
  Nishizuka T., Fujita Y, Sato Y, Nakano A, Kakino A, Ohshima S, Kanda T, Yoshimoto R, Sawamura T
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci
  
  Volume: 87 Pages: 104-113
- NAID
  130000669114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] The discovery of LOX-1, its ligands and clinical significance2011
- Author(s)
  Yoshimoto R, Fujita Y, Kakino A, Iwamoto S, Takaya T, Sawamura T
- Journal Title
  
  Cardiovascular Drugs and Therapy
  
  Volume: 25 Pages: 79-391
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] Lectin-like oxidized LDL receptor 1 is in volved in CRP-mediated complement activation2011
- Author(s)
  Fujita Y, Yamaguchi S, Kakino A, Iwamoto S, Yoshimoto R, Sawamura T
- Journal Title
  
  Clinical Chemistry
  
  Volume: 57 Pages: 1398-1405
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] C-reactive protein uptake by macrophage cell line via class-A sc avenger receptor2010
- Author(s)
  Fujita Y, Kakino A, Harada-Shiba M, Sato Y, Otsui K, Yoshimoto R, Saw amura T
- Journal Title
  
  Clinical Chemistry
  
  Volume: 56 Pages: 478-481
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] LOX Index, a novel predictive biochemical marker for coronary heart disease and stroke2010
- Author(s)
  Inoue N, Okamura T, Kokubo Y, Fujita Y, Sato Y, Nakanishi M, Yanagida K, Kakino A, Iwamoto S, Watanabe M, Ogura S, Otsui K, Matsuda H, Uchida K, Yoshimoto R, Sawamura T
- Journal Title
  
  Cli Chem
  
  Volume: 56 Pages: 550-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] C-reactive protein uptake by macrophage cell line via class-A scavenger receptor.2010
- Author(s)
  Fujita Y, Kakino A, Harada-Shiba M, Sato Y, Otsui K, Yoshimoto R, Sawamura T
- Journal Title
  
  Cli Chem
  
  Volume: 56 Pages: 478-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790267
[Journal Article] LOX Index, a novel predictive biochemical marker for coronary heart disease and stroke2010
- Author(s)
  Inoue N, Okamura T, Kokubo Y, Fujita Y, Sato Y, Nakanishi M, Yanagida K, Kakino A, Iwamoto S, Watanabe M, Ogura S, Otsui K, Matsuda H, Uchida K, Yoshimoto R, Sawamura T
- Journal Title
  
  Clinical Chemistry
  
  Volume: 56 Pages: 550-558
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] 抗肥満薬の開発について(標的分子の決定から臨床開発品の選定まで)2011
- Author(s)
  善本亮
- Organizer
  第151回日本獣医学会
- Place of Presentation
  府中
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] Procyanidin inhibits oxidized LDL binding to LOX-1 and suppresses vascular lipid accumulation in SHR-SP rats2011
- Author(s)
  Yoshimoto R, Nishizuka T, Fujita Y, Sato Y, Nakano A, Kakino A, Ohshima S, Kanda T, Sawamura T
- Organizer
  日本動脈硬化学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] Procyanidin is a naturally-occurnig LOX-1 antagonist and inhibits lipid accumulation in vascular wall2011
- Author(s)
  善本亮、西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、沢村達也
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] Procyanidin is a naturally-occurnig LOX-1 antagonist and inhibits lipid accumulation in vascular wall.2011
- Author(s)
  善本亮、西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、沢村達也
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] 抗肥満薬の開発について(標的分子の決定から臨床開発品の選定まで):シンポジウム2011
- Author(s)
  善本亮
- Organizer
  第151回日本獣医学会
- Place of Presentation
  府中
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] プロシアニジンは酸化LDL受容体LOX-1のアンタゴニストであり、ラット血管壁への脂質沈着を抑制する2010
- Author(s)
  西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、善本亮、沢村達也
- Organizer
  第38回薬物活性シンポジウム・第20回日本循環薬理学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] Pancreatic islet regeneration in type I diabetes mice receiving portal islet transplantation.2010
- Author(s)
  Yoshimoto R, Saito M, Fushiki H, Yoshimoto R, Seo T
- Organizer
  70th American Diabetes Association
- Place of Presentation
  Orland, Florida
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] 酸化LDL測定のための人工標準蛋白作成2010
- Author(s)
  岩元真、藤田佳子、垣野明美、柳田一樹、善本亮、沢村達也
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790267
[Presentation] Pancreatic islet regeneration in type I diabetes mice receiving portal islet transplantation2010
- Author(s)
  Yoshimoto R, Saito M, Fushiki H, Yoshimoto R, Seo T
- Organizer
  70th American Diabetes Association
- Place of Presentation
  Orland, Florida
- Data Source
  KAKENHI-PROJECT-22790267

1. 原馬明子 (80727917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOSHIMOTO RYO 善本 亮

YOSHIMOTO Ryo 善本 亮

Research Projects

Research Products

Co-Researchers

母乳の中鎖脂肪酸は乳児や成長後のエネルギー代謝にどのような影響を与えるか？Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of LOX-1 in the development of non-alcoholic steat ohepatitis(NASH)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] An alternative protein standard to measure activity of LOX-1 ligand containing apoB(LAB)-utilization of anti-LOX-1 single-chain antibody fused to aopB fragment2011

Author(s)

Journal Title

Data Source

[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The discovery of LOX-1, its ligands and clinical significance2011

Author(s)

Journal Title

Data Source

[Journal Article] Lectin-like oxidized LDL receptor 1 is in volved in CRP-mediated complement activation2011

Author(s)

Journal Title

Data Source

[Journal Article] C-reactive protein uptake by macrophage cell line via class-A sc avenger receptor2010

Author(s)

Journal Title

Data Source

[Journal Article] LOX Index, a novel predictive biochemical marker for coronary heart disease and stroke2010

Author(s)

Journal Title

Data Source

[Journal Article] C-reactive protein uptake by macrophage cell line via class-A scavenger receptor.2010

Author(s)

Journal Title

Data Source

[Journal Article] LOX Index, a novel predictive biochemical marker for coronary heart disease and stroke2010

Author(s)

Journal Title

Data Source

[Presentation] 抗肥満薬の開発について(標的分子の決定から臨床開発品の選定まで)2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Procyanidin inhibits oxidized LDL binding to LOX-1 and suppresses vascular lipid accumulation in SHR-SP rats2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Procyanidin is a naturally-occurnig LOX-1 antagonist and inhibits lipid accumulation in vascular wall2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Procyanidin is a naturally-occurnig LOX-1 antagonist and inhibits lipid accumulation in vascular wall.2011

Author(s)

Organizer

Place of Presentation

YOSHIMOTO RYO 善本亮

YOSHIMOTO Ryo 善本亮