Kijima Toshiki 木島敏樹

… Alternative Names

木島敏樹キジマトシキ

KIJIMA Toshiki 木島敏樹

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Researcher Number	90569500
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 獨協医科大学, 医学部, 講師 2019: 獨協医科大学, 医学部, 講師 2018: 東京医科歯科大学, 医学部附属病院, 助教 2014: 東京医科歯科大学, 医学部附属病院, その他 2011 – 2012: 東京医科歯科大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 56030:Urology-related / Urology
Keywords	Principal Investigator 前立腺癌 / 熱ショック蛋白質 / 化学療法 / プロテアゾーム / ユビキチン / 蛋白質分解 / ブロモドメイン蛋白質 / 去勢抵抗性前立腺癌 / アンドロゲン受容体 / 去勢抵抗性 … More / 熱ショックタンパク質 / 熱ショック因子 / ホルモン療法 / 膀胱癌 / 腎細胞癌 / 放射線療法 / 泌尿器癌 / 放射線治療 / ビスホスホネート Less

Research Projects
(4 results)
Research Products
(16 results)

CHAperone-Mediated Protein degradation (CHAMP) based novel therapy for castration resistant prostate cancerPrincipal Investigator
- Principal Investigator
  
  木島敏樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Dokkyo Medical University
Novel therapy targeting androgen receptor splice variants by inhibiting heat shock factor 1 (HSF1) for the treatment of castration-resistant prostate cancerPrincipal Investigator
- Principal Investigator
  
  Kijima Toshiki
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Dokkyo Medical University
  Tokyo Medical and Dental University
ビスホスホネートによるSTAT1抑制機構および泌尿器癌治療増感作用の解析Principal Investigator
- Principal Investigator
  
  木島敏樹
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Tokyo Medical and Dental University
Sensitizing effects of bisphosphonate to radiotherapy and chemotherapy in urologic cancers.Principal Investigator
- Principal Investigator
  
  KIJIMA Toshiki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2019 2018 2013

All Journal Article Presentation

[Journal Article] Prostate-specific antigen kinetics contributes to decision making for biopsy referral: the predictive implication for PSA retest in patients with elevated PSA levels.2023
- Author(s)
  Kobayashi M, Kijima T, Yashi M, Kamai T.
- Journal Title
  
  Prostate Int
  
  Volume: 11 Issue: 1 Pages: 27-33
- DOI
  10.1016/j.prnil.2022.08.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09534
[Journal Article] A case of adrenal undifferentiated pleomorphic sarcoma with tertiary lymphoid structures responded to pembrolizumab.2023
- Author(s)
  Kokubun H, Kijima T, Takada-Owada A, Mamiya D, Kurashina R, Okubo N, Uematsu T, Takei K, Ishida K, Kamai T.
- Journal Title
  
  IJU Case Rep
  
  Volume: 6 Issue: 6 Pages: 440-444
- DOI
  10.1002/iju5.12643
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09534
[Journal Article] Association between Immune Checkpoint Inhibitor Treatment Outcomes and Body Composition Factors in Metastatic Renal Cell Carcinoma Patients.2023
- Author(s)
  Takei K, Kijima T, Okubo N, Kurashina R, Kokubun H, Uematsu T, Betsunoh H, Yashi M, Kamai T.
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 23 Pages: 5591-5591
- DOI
  10.3390/cancers15235591
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09534
[Journal Article] A case of perirenal extra-adrenal myelolipoma mimicking liposarcoma.2023
- Author(s)
  Shimoda H, Kijima T, Takada-Owada A, Ishida K, Kamai T.
- Journal Title
  
  Urol Case Rep
  
  Volume: 50 Pages: 102523-102523
- DOI
  10.1016/j.eucr.2023.102523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09534
[Journal Article] Increased co-expression of stromal HHLA2 and fibroblast activation protein in upper tract urothelial carcinoma2023
- Author(s)
  Nishihara Daisaku、Kijima Toshiki、Arai Kyoko、Kamai Takao
- Journal Title
  
  International Urology and Nephrology
  
  Volume: 55 Issue: 4 Pages: 867-874
- DOI
  10.1007/s11255-022-03458-0
- Data Source
  KAKENHI-PROJECT-22K09534
[Journal Article] Monitoring of the Heat Shock Response with a Real-Time Luciferase Reporter.2023
- Author(s)
  Ackerman A, Kijima T, Eguchi T, Prince TL.
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2693 Pages: 1-11
- DOI
  10.1007/978-1-0716-3342-7_1
- ISBN
  9781071633410, 9781071633427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09534
[Journal Article] Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation2022
- Author(s)
  Kamai Takao、Murakami Satoshi、Arai Kyoko、Nishihara Daisaku、Uematsu Toshitaka、Ishida Kazuyuki、Kijima Toshiki
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 289-289
- DOI
  10.1186/s12885-022-09415-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09534, KAKENHI-PROJECT-20K09546
[Journal Article] Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma2022
- Author(s)
  Kamai Takao、Murakami Satoshi、Arai Kyoko、Ishida Kazuyuki、Kijima Toshiki
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 7 Pages: 2368-2377
- DOI
  10.1111/cas.15379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K09534, KAKENHI-PROJECT-20K09546
[Journal Article] Cancer immunohistogram representing cancer-immunity cycle by immunohistochemistry predicts the efficacy of immune checkpoint inhibitors in urological cancer patients2022
- Author(s)
  Kijima Toshiki、Kubo Terufumi、Nishihara Daisaku、Nukui Akinori、Hirohashi Yoshihiko、Torigoe Toshihiko、Kamai Takao
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 10617-10617
- DOI
  10.1038/s41598-022-14700-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09534, KAKENHI-PROJECT-21K18257
[Journal Article] Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress.2019
- Author(s)
  Kijima T, Prince T, Neckers L, Koga F, Fujii Y.
- Journal Title
  
  Expert Opin Ther Targets.
  
  Volume: 23 Issue: 5 Pages: 369-377
- DOI
  10.1080/14728222.2019.1602119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16686
[Journal Article] ZOLEDRONIC ACID SENSITIZES RENAL CELL CARCINOMA CELLS TO RADIATION BY DOWNREGULATING STAT12013
- Author(s)
  Toshiki Kijima
- Journal Title
  
  PLOS ONE
  
  Volume: in press. Issue: 5 Pages: e64615-e64615
- DOI
  10.1371/journal.pone.0064615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791745
[Presentation] Tertiary lymphoid structures correlate with better prognosis in retroperitoneal sarcoma2024
- Author(s)
  Kijima Toshiki, Takada-Owada Atsuko, Shimoda Hiroki, Imasato Naoki, Nakamura Gaku, Kokubun Hidetoshi, Suzuki Issei, Takei Kohei, Nishihara Daisaku, Betsunoh Hironori, Nakazato Yoshimasa, Yashi Masahiro, Ishida Kazuyuki, Kamai Takao.
- Organizer
  the 38th Annual European Association of Urology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09534
[Presentation] Tertiary lymphoid structures correlate with better prognosis in retroperitoneal sarcoma2023
- Author(s)
  Kijima Toshiki, Takada-Owada Atsuko, Shimoda Hiroki, Imasato Naoki, Nakamura Gaku, Kokubun Hidetoshi, Suzuki Issei, Takei Kohei, Nishihara Daisaku, Betsunoh Hironori, Nakazato Yoshimasa, Yashi Masahiro, Ishida Kazuyuki, Kamai Takao.
- Organizer
  the 38th Annual European Association of Urology Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09534
[Presentation] Novel therapy targeting androgen receptor splice variants by inhibiting heat shock factor 1 (HSF1) for the treatment of castration-resistant prostate cancer2018
- Author(s)
  木島敏樹、吉田宗一郎、横山みなと、石岡淳一郎、松岡陽、斎藤一隆、木原和徳、藤井靖久
- Organizer
  日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K16686
[Presentation] Radiosensitizing effect of zoledronic acid on renal cell carcinoma cells by downregulating STAT12013
- Author(s)
  Toshiki Kijima
- Organizer
  American Urological Association, 2013 annual meeting
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2013-05-08
- Data Source
  KAKENHI-PROJECT-23791745
[Presentation] Zoledronic acid sensitizes renal cell carcinoma cells to radiation by downregulating STAT12013
- Author(s)
  Toshiki Kijima
- Organizer
  European Association of Urology, 28th annual congress
- Place of Presentation
  Milan, Italy
- Year and Date
  2013-03-19
- Data Source
  KAKENHI-PROJECT-23791745

Kijima Toshiki 木島 敏樹

木島 敏樹 キジマ トシキ

KIJIMA Toshiki 木島 敏樹

Research Projects

Research Products

CHAperone-Mediated Protein degradation (CHAMP) based novel therapy for castration resistant prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Novel therapy targeting androgen receptor splice variants by inhibiting heat shock factor 1 (HSF1) for the treatment of castration-resistant prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ビスホスホネートによるSTAT1抑制機構および泌尿器癌治療増感作用の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sensitizing effects of bisphosphonate to radiotherapy and chemotherapy in urologic cancers.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Prostate-specific antigen kinetics contributes to decision making for biopsy referral: the predictive implication for PSA retest in patients with elevated PSA levels.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of adrenal undifferentiated pleomorphic sarcoma with tertiary lymphoid structures responded to pembrolizumab.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association between Immune Checkpoint Inhibitor Treatment Outcomes and Body Composition Factors in Metastatic Renal Cell Carcinoma Patients.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of perirenal extra-adrenal myelolipoma mimicking liposarcoma.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased co-expression of stromal HHLA2 and fibroblast activation protein in upper tract urothelial carcinoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monitoring of the Heat Shock Response with a Real-Time Luciferase Reporter.2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Increased expression of Nrf2 and elevated glucose uptake in pheochromocytoma and paraganglioma with SDHB gene mutation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Association of Nrf2 expression and mutation with Weiss and Helsinki scores in adrenocortical carcinoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cancer immunohistogram representing cancer-immunity cycle by immunohistochemistry predicts the efficacy of immune checkpoint inhibitors in urological cancer patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress.2019

Author(s)

Journal Title

DOI

Data Source

Kijima Toshiki 木島敏樹

木島敏樹キジマトシキ

KIJIMA Toshiki 木島敏樹