Suita Kenji 吹田憲治

… Alternative Names

SUITA KENJI 吹田憲治

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Researcher Number	90569542
Affiliation (Current)	2025: 鶴見大学, 歯学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2023: 鶴見大学, 歯学部, 助教 2016 – 2018: 鶴見大学, 歯学部, 学部助手 2012 – 2015: 横浜市立大学, 医学(系)研究科(研究院), 特任助手
Review Section/Research Field	Principal Investigator Basic Section 57080:Social dentistry-related / General physiology
Keywords	Principal Investigator Epac / cAMP / ベータアドレナリン受容体 / アデニル酸シクラーゼ / 分子標的薬 / 不整脈 / 心疾患 / 咬合不調和 / 心機能障害 / 口腔機能異常 … More / 心機能 / 自律神経系 / ストレス / 心臓リモデリング / 心臓組織リモデリング / βアドレナリン受容体シグナル / 心房細動 / 口腔疾患 / 抗ヘルペス剤 / ベータアドレナリン受容体シグナル / 治療薬 / βアドレナリン受容体 / Epac1 / サイクリックAMP / カテコラミン / セカンドメッセンジャー / ベータアドレナリン受容体シグナル伝達 Less

咬合不調和に対する心臓のストレス応答におけるEpac1の重要性Principal Investigator
- Principal Investigator
  
  吹田憲治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Tsurumi University
Analysis of the pathogenesis of atrial fibrillation induced by oral disease via a cAMP target molecule EpacPrincipal Investigator
- Principal Investigator
  
  Suita Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57080:Social dentistry-related
- Research Institution
  Tsurumi University
Development of new antiarrhythmic drugs alternative to beta blocker therapyPrincipal Investigator
- Principal Investigator
  
  Suita Kenji
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Tsurumi University
  Yokohama City University
Analysis of potential molecular targets in the beta-adrenergic receptor signal pathway for new drug therapy of catecholamine-induced arrhythmiasPrincipal Investigator
- Principal Investigator
  
  SUITA KENJI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Yokohama City University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 第57回日本生体医工学会大会　学会関連印象記2018
- Author(s)
  吹田憲治
- Total Pages
  3
- Publisher
  日本循環制御医学会
- Data Source
  KAKENHI-PROJECT-15K18973
[Journal Article] Effects of the angiotensin-converting enzyme inhibitor captopril on occlusal-disharmony-induced cardiac dysfunction in mice2023
- Author(s)
  Ito Aiko、Ohnuki Yoshiki、Suita Kenji、Matsuo Ichiro、Ishikawa Misao、Mitsubayashi Takao、Mototani Yasumasa、Kiyomoto Kenichi、Tsunoda Michinori、Morii Akinaka、Nariyama Megumi、Hayakawa Yoshio、Tomonari Hiroshi、Okumura Satoshi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 199127-199127
- DOI
  10.1038/s41598-023-43099-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17171, KAKENHI-PROJECT-21K10242, KAKENHI-PROJECT-22K10255, KAKENHI-PROJECT-23K09448, KAKENHI-PROJECT-23K09493, KAKENHI-PROJECT-23K09517
[Journal Article] Vidarabine, an anti-herpes agent, improves Porphyromonas gingivalis lipopolysaccharide-induced cardiac dysfunction in mice2023
- Author(s)
  Tsunoda Michinori、Matsuo Ichiro、Ohnuki Yoshiki、Suita Kenji、Ishikawa Misao、Mitsubayashi Takao、Ito Aiko、Mototani Yasumasa、Kiyomoto Kenichi、Morii Akinaka、Nariyama Megumi、Hayakawa Yoshio、Gomi Kazuhiro、Okumura Satoshi
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 73 Issue: 1 Pages: 18-18
- DOI
  10.1186/s12576-023-00873-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17171, KAKENHI-PROJECT-21K10242, KAKENHI-PROJECT-22K10255, KAKENHI-PROJECT-23K09448, KAKENHI-PROJECT-23K09493, KAKENHI-PROJECT-20K10304
[Journal Article] Oral angiotensin-converting enzyme inhibitor captopril protects the heart from Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice2023
- Author(s)
  Kiyomoto Kenichi、Matsuo Ichiro、Suita Kenji、Ohnuki Yoshiki、Ishikawa Misao、Ito Aiko、Mototani Yasumasa、Tsunoda Michinori、Morii Akinaka、Nariyama Megumi、Hayakawa Yoshio、Amitani Yasuharu、Gomi Kazuhiro、Okumura Satoshi
- Journal Title
  
  PLOS ONE
  
  Volume: 18 Issue: 11 Pages: 0292624-0292624
- DOI
  10.1371/journal.pone.0292624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17171, KAKENHI-PROJECT-21K10242, KAKENHI-PROJECT-22K10255, KAKENHI-PROJECT-23K09448, KAKENHI-PROJECT-23K09493, KAKENHI-PROJECT-23K09517, KAKENHI-PROJECT-22K21003
[Journal Article] Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice2022
- Author(s)
  Matsuo Ichiro、Kawamura Naoya、Ohnuki Yoshiki、Suita Kenji、Ishikawa Misao、Matsubara Takehiro、Mototani Yasumasa、Ito Aiko、Hayakawa Yoshio、Nariyama Megumi、Morii Akinaka、Kiyomoto Kenichi、Tsunoda Michinori、Gomi Kazuhiro、Okumura Satoshi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 6 Pages: e0258823-e0258823
- DOI
  10.1371/journal.pone.0258823
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10304, KAKENHI-PROJECT-21K10242, KAKENHI-PROJECT-22K10255, KAKENHI-PROJECT-17K11977, KAKENHI-PROJECT-20K10305
[Journal Article] Vidarabine, an anti-herpes agent, prevents occlusal-disharmony-induced cardiac dysfunction in mice2022
- Author(s)
  Hayakawa Y, Suita K, Ohnuki Y, Mototani Y, Ishikawa M, Ito A, Nariyama M, Morii A, Kiyomoto K, Tsunoda M, Matsuo I, Kawahara H, Okumura S
- Journal Title
  
  J Physiol Sci
  
  Volume: 72 Issue: 1 Pages: 2-16
- DOI
  10.1186/s12576-022-00826-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-18K09848, KAKENHI-PROJECT-19K24109, KAKENHI-PROJECT-21K17171, KAKENHI-PROJECT-21K10242, KAKENHI-PROJECT-22K10255, KAKENHI-PROJECT-17K11977, KAKENHI-PROJECT-20K10305
[Journal Article] Effects of chronic Porphylomonas gingivalis lipopolysaccharide infusion on cardiac dysfunction in mice2021
- Author(s)
  Matsuo I, Ohnuki Y, Suita K, Ishikawa M, Mototani Y, Ito A, Hayakawa Y, Nariyama M, Morii A, Kiyomoto K, Tsunoda M, Gomi K, Okumura S
- Journal Title
  
  J Oral Biosci
  
  Volume: 63 Issue: 4 Pages: 397-400
- DOI
  10.1016/j.job.2021.10.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-18K09848, KAKENHI-PROJECT-19K24109, KAKENHI-PROJECT-17K11977, KAKENHI-PROJECT-20K10304, KAKENHI-PROJECT-20K10305, KAKENHI-PROJECT-21K10242, KAKENHI-PROJECT-21K17171
[Journal Article] 実験的咬合異常がマウスの心機能に及ぼす影響について2020
- Author(s)
  八木澤由佳、吹田憲治、大貫芳樹、伊藤愛子、梅木大輔、友成　博、奥村　敏
- Journal Title
  
  循環制御
  
  Volume: 41 Pages: 38-45
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10305
[Journal Article] Effects of occlusal disharmony on susceptibility to atrial fibrillation in mice2020
- Author(s)
  Suita K, Yagisawa Y, Ohnuki Y, Umeki D, Nariyama M, Ito A, Hayakawa Y, Matsuo I, Mototani Y, Saeki Y, Okumura S
- Journal Title
  
  Sci Rep
  
  Volume: 10(1) Issue: 1 Pages: 13765-13765
- DOI
  10.1038/s41598-020-70791-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11977, KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-20K10305, KAKENHI-PROJECT-17K12067
[Journal Article] Effects of occlusal disharmony on cardiac fibrosis, myocyte apoptosis and myocyte oxidative DNA damage in mice.2020
- Author(s)
  Yagisawa Y, Suita K, Ohnuki Y, Ishikawa M, Mototani Y, Ito A, Matsuo I, Hayakawa Y, Nariyama M, Umeki D, Saeki Y, Amitani Y, Nakamura Y, Tomonari H, Okumura
- Journal Title
  
  PLoS One
  
  Volume: 15(7) Issue: 7 Pages: e0236547-e0236547
- DOI
  10.1371/journal.pone.0236547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11977, KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-18K09848, KAKENHI-PROJECT-20K10304, KAKENHI-PROJECT-20K10305, KAKENHI-PROJECT-17K12067
[Journal Article] Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice2019
- Author(s)
  Prajapati R, Fujita T, Suita K, Nakamura T, Cai W, Hidaka Y, Umemura M, Yokoyama U, Knollmann BC, Okumura S, Ishikawa Y
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 2 Pages: 295-303
- DOI
  10.1253/circj.CJ-18-0743
- NAID
  130007557004
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-17K15560, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-19K08563, KAKENHI-PROJECT-18K15013
[Journal Article] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced arrhythmias without adverse effect on heart function in mice2018
- Author(s)
  Suita Kenji、Fujita Takayuki、Cai Wenqian、Hidaka Yuko、Jin Huiling、Prajapati Rajesh、Umemura Masanari、Yokoyama Utako、Sato Motohiko、Knollmann Bj?rn C.、Okumura Satoshi、Ishikawa Yoshihiro
- Journal Title
  
  Pfl?gers Archiv - European Journal of Physiology
  
  Volume: 未定 Issue: 6 Pages: 923-935
- DOI
  10.1007/s00424-018-2121-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-17K01828, KAKENHI-PROJECT-18K06862, KAKENHI-PROJECT-18KT0073, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16H05358
[Journal Article] A New Drug Therapy for Heart Failure by Anti-Herpesvirus Agent, an Inhibitor of Cardiac Adenylyl Cyclase2017
- Author(s)
  吹田憲治
- Journal Title
  
  CIRCULATION CONTROL
  
  Volume: 38 Issue: 2 Pages: 126-132
- DOI
  10.11312/ccm.38.126
- NAID
  130006067759
- ISSN
  0389-1844
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K18973
[Journal Article] Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.2017
- Author(s)
  Huiling Jin, Takayuki Fujita, Meihua Jin, Reiko Kurotani, Iyuki Namekata, Shogo Hamaguchi, Yuko Hidaka, Wenqian Cai, Kenji Suita, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Rajesh Prajapati, Chen Liang, Masanari Umemura, Utako Yokoyama, Motohiko Sato, Hikaru Tanaka, Satoshi Okumura, Yoshihiro Ishikawa.
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 108 Pages: 170-180
- DOI
  10.1016/j.yjmcc.2017.05.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-17K15460, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K08247, KAKENHI-PROJECT-15K09208, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300
[Journal Article] Vidarabine, an Anti-Herpes Virus Agent, Protects Against the Development of Heart Failure With Relatively Mild Side-Effects on Cardiac Function in a Canine Model of Pacing-Induced Dilated Cardiomyopathy2016
- Author(s)
  T. Nakamura, T. Fujita, M. Kishimura, K. Suita, Y. Hidaka, W. Cai, M. Umemura, U. Yokoyama, M. Uechi, and Y. Ishikawa
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 12 Pages: 2496-2505
- DOI
  10.1253/circj.CJ-16-0736
- NAID
  130005284971
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-15K18973
[Journal Article] Disruption of Epac1 protects the heart from adenylyl cyclase type 5-mediated cardiac dysfunction．2016
- Author(s)
  Cai W，Fujita T，Hidaka Y，Jin H，Suita K，Prajapati R，Liang C，Umemura M，Yokoyama U，Sato M，Okumura S，Ishikawa Y
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 475 Issue: 1 Pages: 1-7
- DOI
  10.1016/j.bbrc.2016.04.123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-16K08508, KAKENHI-PROJECT-15K18973
[Journal Article] Role of phosphodiesterase 4 expression in the epac1 signaling-dependent skeletal muscle hypertrophic action of clenbuterol．2016
- Author(s)
  Ohnuki Y，Umeki D，Mototani Y，Shiozawa K，Nariyama M，Ito A，Kawamura N，Yagisawa Y，Jin H，Cai W，Suita K，Saeki Y，Fujita T，Ishikawa Y，Okumura S.
- Journal Title
  
  Physiological reports.
  
  Volume: 4 Issue: 10 Pages: e12791-e12791
- DOI
  10.14814/phy2.12791
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05300, KAKENHI-PROJECT-26463127, KAKENHI-PROJECT-16K15205, KAKENHI-PROJECT-26463103, KAKENHI-PROJECT-15K18973
[Journal Article] Oscillation of cAMP and Ca(2+) in cardiac myocytes: a systems biology approach2015
- Author(s)
  Kamide T, Okumura S, Ghosh S, Shinoda Y, Mototani Y, Ohnuki Y, Jin H, Cai W, Suita K, Sato I, Umemura M, Fujita T, Yokoyama U, Sato M, Furutani K, Kitano H, Ishikawa Y
- Journal Title
  
  The Journal of Physiological Sciences
  
  Volume: 65(2) Issue: 2 Pages: 195-200
- DOI
  10.1007/s12576-014-0354-3
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136003, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24590319, KAKENHI-PROJECT-24790219, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506, KAKENHI-PLANNED-22136002, KAKENHI-PROJECT-25293236
[Journal Article] Norepinephrine-induced adrenergic activation strikingly increased the atrial fibrillation duration through β1- and α1-adrenergic receptor-mediated signaling in mice.2015
- Author(s)
  Suita K, Fujita T, Hasegawa N, Cai W, Jin H, Hidaka Y, Prajapati R, Umemura M, Yokoyama U, Sato M, Okumura S, Ishikawa Y.
- Journal Title
  
  PLoS One.
  
  Volume: 23;10(7) Issue: 7 Pages: e0133664-e0133664
- DOI
  10.1371/journal.pone.0133664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293236
[Journal Article] Protective Effects of Clenbuterol against Dexamethasone-Induced Masseter Muscle Atrophy and Myosin Heavy Chain Transition2015
- Author(s)
  Umeki D, Ohnuki Y, Mototani Y, Shiozawa K, Suita K, Fujita T, Nakamura Y, Saeki Y, Okumura S
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 6 Pages: e0128263-e0128263
- DOI
  10.1371/journal.pone.0128263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K11356, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-26861803
[Journal Article] Coupling of beta1-adrenergic receptor to type 5 adenylyl cyclase and its physiological relevance in cardiac myocytes.2015
- Author(s)
  Tsunematsu T, Okumura S, Mototani Y, Ohnuki Y, Jin H, Cai W, SuitaK, Sato I, Umemura M, Yokoyama U, Sato M, Fujita T, and Ishikawa Y.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 458 Issue: 3 Pages: 531-535
- DOI
  10.1016/j.bbrc.2015.01.149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24590280, KAKENHI-PROJECT-24790219, KAKENHI-PUBLICLY-25116719, KAKENHI-PUBLICLY-25136721, KAKENHI-PROJECT-25670131, KAKENHI-PROJECT-26670506, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-25293236
[Journal Article] Disruption of Epac1 decreases phosphorylation of phospholamban and protects the heart against stresses2014
- Author(s)
  Okumura S, Fujita T, Cai W, Jin M, Namekata I, Mototani Y, Jin H, Ohnuki Y, Tsuneoka Y, Kurotani R, Suita K, Kawakami Y, Hamaguchi S, Abe T, Kiyonari H, Tsunematsu T, Bai Y, Suzuki S, Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko H, Adachi-Akahane S, Tanaka H, Ishikawa Y
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] Epac1による心筋収縮性およびミオシン軽鎖２リン酸化の制御機構2024
- Author(s)
  大貫芳樹、吹田憲治、奥村敏
- Organizer
  第101回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] 咬合不調和は心筋カルシウムシグナルの異常を介して心機能障害を引き起こす　～抗ヘルペス薬ビダラビンを用いたアデニル酸シクラーゼ阻害の有効性～2024
- Author(s)
  吹田憲治、早川佳男、大貫芳樹、奥村敏
- Organizer
  第101回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] アンジオテンシン変換酵素阻害薬カプトプリルの咬合異常に起因する心機能障害に対する影響2023
- Author(s)
  伊藤愛子、大貫芳樹、吹田憲治、石川美佐緒、松尾一朗、早川佳男、成山明具美、友成博、奥村敏
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] Mitf遺伝子変異による咬筋組織リモデリングの誘発機序の解明2023
- Author(s)
  成山明具美、大貫芳樹、吹田憲治、石川美佐緒、伊藤愛子、松尾一朗、早川佳男、朝田芳信、奥村敏
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] 咬合不調和による心機能障害に対するキサンチンオキシターゼ阻害薬アロプリノールの効果の検討2023
- Author(s)
  三ツ林喬央、吹田憲治、松尾一朗、伊藤愛子、清本賢一、角田通則、成山明具美、森井彰仲、大貫芳樹、奥村敏
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] Porphyromonas gingivalis 由来LPSの慢性投与で発症する心機能障害に対する心臓型アデニル酸シクラーゼの抑制効果2023
- Author(s)
  角田通則、大貫芳樹、吹田憲治、松尾一朗、早川佳男、清本賢一、森井彰仲、成山明具美、五味一博、奥村敏
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] レニン-アンジオテンシン系がPorphyromonas gingivalis 由来LPSによる心機能の低下に及ぼす影響2023
- Author(s)
  清本賢一、吹田憲治、大貫芳樹、松尾一朗、角田通則、森井彰仲、三ツ林喬央、伊藤愛子、五味一博、奥村敏
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] Porphyromonas gingivalis 由来LPSの慢性投与下におけるβアドレナリン受容体シグナルの重要性2023
- Author(s)
  松尾一朗、吹田憲治、早川佳男、伊藤愛子、石川美佐緒、成山明具美、成山明具美、大貫芳樹、五味一博、奥村敏
- Organizer
  第65回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-23K09493
[Presentation] レニンアンジオテンシン系の抑制は咬合異常に起因する心機能障害に対する心臓保護効果を示す2022
- Author(s)
  伊藤愛子、大貫芳樹、吹田憲治、石川美佐緒、松尾一朗、早川佳男、成山明具美、友成博、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 酸化ストレス阻害薬 (アロプリノール) の Porphylomonas gingivalis 由来 LPS (PG-LPS) による心機能障害に対する効果2022
- Author(s)
  森井彰仲、吹田憲治、松尾一朗、伊藤愛子、清本賢一、角田通則、成山明具美、大貫芳樹、五味一博、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] レニン-アンジオテンシン系が歯周病による心機能低下に及ぼす影響2022
- Author(s)
  清本賢一、吹田憲治、大貫芳樹、松尾一朗、角田通則、森井彰仲、伊藤愛子、石川美佐緒、五味一博、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 歯周病菌由来 LPS に起因する心疾患発症過程における心臓型アデニル酸シクラーゼの役割2022
- Author(s)
  角田通則、大貫芳樹、吹田憲治、松尾一朗、早川佳男、清本賢一、森井彰仲、成山明具美、五味一博、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] Mitf 遺伝子変異による咬筋リモデリングの誘導2022
- Author(s)
  成山明具美、大貫芳樹、吹田憲治、石川美佐緒、伊藤愛子、松尾一朗、早川佳男、朝田芳信、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] Porphlomonas gingivalis 由来 LPS の慢性投与下における心疾患発症過程には TLR4-NOX4 シグナルが重要である2022
- Author(s)
  松尾一朗、吹田憲治、早川佳男、伊藤愛子、石川美佐緒、成山明具美、大貫芳樹、五味一博、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 心臓型アデニル酸シクラーゼ遮断薬 (ビダラビン) によるマウス咬合異常モデルに見られる心筋障害に対する保護効果の検討2022
- Author(s)
  早川佳男、大貫芳樹、吹田憲治、石川美佐緒、伊藤愛子、松尾一朗、清本賢一、角田通則、河原博、奥村敏
- Organizer
  第64回歯科基礎医学会学術集会、徳島大学
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] レニン-アンジオテンシン系が歯周病由来LPSによる心筋線維化に及ぼす影響2021
- Author(s)
  清本賢一、吹田憲治、大貫芳樹、松尾一朗、角田通則、森井彰仲、伊藤愛子、石川美佐緒、奥村敏、五味一博
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] Porphylomonas gingivalis 由来LPSの慢性投与下における心疾患発症メカニズムの解明2021
- Author(s)
  松尾一朗、吹田憲治、早川佳男、伊藤愛子、石川美佐緒、清本賢一、角田通則、大貫芳樹、五味一博、奥村敏
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 咬合異常によるストレスは、レニン-アンジオテンシン系を介して心筋のアポトーシスを引き起こす2021
- Author(s)
  伊藤愛子、大貫芳樹、吹田憲治、石川美佐緒、松尾一朗、早川佳男、成山明具美、友成博、奥村敏
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] Porphylomonas gingivalis 由来LPSの慢性投与下で発症する心機能障害に対する心臓型アデニル酸シクラーゼの抑制効果2021
- Author(s)
  角田通則、大貫芳樹、吹田憲治、松尾一朗、早川佳男、清本賢一、森井彰仲、成山明具美、五味一博、奥村敏
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 咬合異常により惹起された慢性交感神経刺激状態による心機能障害に対する抗ヘルペス薬（ビダラビン）の予防効果2021
- Author(s)
  早川佳男、大貫芳樹、吹田憲治、石川美佐緒、伊藤愛子、松尾一朗、清本賢一、角田通則、河原博、奥村敏
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 酸化ストレス阻害薬（アロプリノール）のPorphylomonas gingivalis由来LPS（PG-LPS) による心機能障害に対する抑制効果2021
- Author(s)
  森井彰仲、吹田憲治、松尾一朗、伊藤愛子、清本賢一、角田通則、成山明具美、大貫芳樹、五味一博、奥村敏
- Organizer
  第63回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] Effect of occlusal disharmony-induced stress on heart function in mice.2020
- Author(s)
  Suita K, Ohnuki Y, Okumura S
- Organizer
  第126回日本解剖学会総会・全国学術集会、第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] 咬合不調和による慢性的な交感神経系の活性化は心房細動に対する脆弱性を高める．2020
- Author(s)
  吹田憲治，八木澤由佳，早川佳男，伊藤愛子，松尾一朗，梅木大輔，大貫芳樹，奥村　敏
- Organizer
  第62回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K10305
[Presentation] Usefulness of anti-arrhythmic drug therapy targeting cardiac adenylyl cyclase.2019
- Author(s)
  Suita K, Fujita T, Okumura S, Ishikawa Y
- Organizer
  FAOPS 9th Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] 心臓型アデニル酸シクラーゼを標的とした新しい不整脈薬物治療．2018
- Author(s)
  吹田憲治，奥村敏，石川義弘
- Organizer
  第57回日本生体医工学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] Effect of enforced bite-opening on heart in mice.2018
- Author(s)
  Suita K, Ohnuki Y, Okumura S
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] 抗ヘルペス剤ビダラビンによる酸化ストレスの低減を介した不整脈抑制作用．2018
- Author(s)
  吹田憲治，奥村敏，石川義弘
- Organizer
  第27回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] 強制的開口負荷が心機能および心筋細胞内シグナル伝達に与える影響の解析．2018
- Author(s)
  吹田憲治，八木澤由佳，大貫芳樹，梅木大輔，石川美佐緒, 伊藤愛子，川村直矢，中村芳樹，奥村敏
- Organizer
  第60回日本歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] 開口負荷がマウスの心房に与える影響．2017
- Author(s)
  吹田憲治，八木澤由佳，大貫芳樹，梅木大輔，石川美佐緒, 伊藤愛子，川村直矢，中村芳樹，奥村敏
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] Inhibition of cardiac adenylyl cyclase suppresses catecholamine-induced arrhythmias without deteriorating heart function．2017
- Author(s)
  Suita K, Fujita T, Okumura S, Ishikawa Y
- Organizer
  第94回日本生理学会大会，日本病態生理学会連携シンポジウム「自律神経研究の新しい流れと病態生理学」
- Place of Presentation
  アクトシティ浜松（静岡）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K18973
[Presentation] 抗ヘルペス薬による心房細動抑制．2014
- Author(s)
  吹田憲治、藤田孝之、奥村敏、石川義弘
- Organizer
  第131回日本薬理学会関東部会
- Place of Presentation
  横浜市立大学福浦キャンパス看護棟（横浜）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] Vidarabine, an anti-herpesvirus agent, attenuates Ca2+ leak from sarcoplasmic reticulum in cardiomyocytes and prevents atrial fibrillation in mice2014
- Author(s)
  Suita K, Cai W, Jin H, Jin M, Fujita T, Okumura S, Ishikawa Y
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤はCalsequestrin 2ノックアウトマウスに誘発した心室性不整脈を抑制する2014
- Author(s)
  吹田憲治、藤田孝之、金慧玲、蔡文倩、奥村敏、石川義弘
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス（鹿児島県）
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] 抗ヘルペス剤ビダラビンはマウスの心房細動を抑制する2013
- Author(s)
  吹田憲治
- Organizer
  第９０回日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] Inhibitor of cardiac adenylyl cyclase prevents atrial fibrillation in mice2013
- Author(s)
  Suita K, Cai W, Jin H, Jin M, Fujita T, Okumura S, Ishikawa Y
- Organizer
  HD Physiology, the 2nd International Symposium 2013
- Place of Presentation
  MARUNOUCHI MY PLAZA Hall（東京都）
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤ビダラビンによる不整脈治療の可能性2013
- Author(s)
  吹田憲治、藤田孝之、石川義弘
- Organizer
  生理学研究所研究会2013
- Place of Presentation
  生理学研究所（愛知県）
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] 心臓型アデニル酸シクラーゼの選択的阻害剤ビダラビンによる心房細動抑制．
- Author(s)
  吹田憲治、藤田孝之、蔡文倩、金、奥村敏、石川義弘
- Organizer
  第35回日本循環制御医学会総会
- Place of Presentation
  九州大学医学部百年講堂（福岡）
- Year and Date
  2014-07-04 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-24790219
[Presentation] Vidarabine, an anti-herpesvirus agent, prevents catecholamine-induced atrial fibrillation in mice.
- Author(s)
  Suita K, Fujita T, Cai W, Hidaka Y, Jin H, Jin M, Okumura S, Ishikawa Y
- Organizer
  European Society of Cardiology, Annual Congress 2014
- Place of Presentation
  バルセロナ（スペイン）
- Year and Date
  2014-08-30 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-24790219

1. ISHIKAWA Yoshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. OKUMURA Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
3. NARIYAMA Megumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
4. NAMEKATA Iyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. YOKOYAMA Utako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. NAKAMURA Yoshiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 伊藤愛子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 大貫芳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 佐藤元彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 北野宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 梅村将就

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 藤田孝之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suita Kenji 吹田 憲治

SUITA KENJI 吹田 憲治

Research Projects

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Co-Researchers

咬合不調和に対する心臓のストレス応答におけるEpac1の重要性Principal Investigator

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Analysis of the pathogenesis of atrial fibrillation induced by oral disease via a cAMP target molecule EpacPrincipal Investigator

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Development of new antiarrhythmic drugs alternative to beta blocker therapyPrincipal Investigator

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Analysis of potential molecular targets in the beta-adrenergic receptor signal pathway for new drug therapy of catecholamine-induced arrhythmiasPrincipal Investigator

Principal Investigator

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[Book] 第57回日本生体医工学会大会 学会関連印象記2018

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[Journal Article] Effects of the angiotensin-converting enzyme inhibitor captopril on occlusal-disharmony-induced cardiac dysfunction in mice2023

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[Journal Article] Vidarabine, an anti-herpes agent, improves Porphyromonas gingivalis lipopolysaccharide-induced cardiac dysfunction in mice2023

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[Journal Article] Oral angiotensin-converting enzyme inhibitor captopril protects the heart from Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice2023

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[Journal Article] Role of TLR4 signaling on Porphyromonas gingivalis LPS-induced cardiac dysfunction in mice2022

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[Journal Article] Vidarabine, an anti-herpes agent, prevents occlusal-disharmony-induced cardiac dysfunction in mice2022

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[Journal Article] Effects of chronic Porphylomonas gingivalis lipopolysaccharide infusion on cardiac dysfunction in mice2021

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[Journal Article] 実験的咬合異常がマウスの心機能に及ぼす影響について2020

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[Journal Article] Effects of occlusal disharmony on susceptibility to atrial fibrillation in mice2020

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[Journal Article] Effects of occlusal disharmony on cardiac fibrosis, myocyte apoptosis and myocyte oxidative DNA damage in mice.2020

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[Journal Article] Usefulness of Exchanged Protein Directly Activated by cAMP (Epac)1-Inhibiting Therapy for Prevention of Atrial and Ventricular Arrhythmias in Mice2019

Author(s)

Suita Kenji 吹田憲治

SUITA KENJI 吹田憲治

[Book] 第57回日本生体医工学会大会　学会関連印象記2018